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BREAST CANCER OVERVIEW Polly Stephens, M.D.
BREAST ANATOMY
breastcancer.org
Ductal Carcinoma In Situ
CALCIFICATIONS
The
Invasive Ductal Carcinoma
Breast cancer
Breast cancer
Vascular/Lymphatic Invasion
Bone scan
Liver metastases
MAMMOGRAPHY
In America, most breast cancers are diagnosed on mammogram
• 1st mammogram age 35 – Or 10 years before your mother was
diagnosed with breast cancer• Yearly starting age 40• About 10% of cancers are not seen on
mammogram. DO YOUR OWN EXAM
BIOPSY
• Ultrasound-guided• Stereotactic• MRI guided biopsy
STEREOTACTIC BIOPSY
ULTRASOUND BIOPSY
INVASIVE DUCTAL CARCINOMA
• Overall survival 75%• Stage
– 0 Ductal carcinoma in situ– I tumor <2cm, no lymph nodes– II tumor 2-5cm, <4 lymph nodes– III tumor >5cm, >4 lymph nodes– IV distant metastases
INFLAMMATORY BREAST CANCER
• P’eau d’orange
Treatment
• Local control– Lumpectomy/mastectomy– Radiation
• Distal control– Chemotherapy
Mammosite
External Beam Radiation
Who needs chemotherapy?
• If there is a risk of cells in the blood stream looking for a place to settle– Bone, Liver, Lung, Brain
• There is no blood test for breast cancer cells in the blood stream
Genetics
• BRCA 1 and 2– Alterations or mutations in these genes
increase ones risk for breast and ovarian cancer
– Only about 5% of breast cancer patients are BRCA +