Breyner, N.M., Hell, R.C.R., Carvalho, L.R.P., Machado, C.B ...Sircol Assay Citations in Scientific...

Sircol Assay Citations in Scientific Literature 2009

Allograft Collagen

Abreu,E.L., Palmer,M.P. and Murray,M.M. (2009) Storage conditions do not have detrimental effect on allograft collagen or scaffold performance. Cell and Tissue Banking, 10, 333-340.

Murine Colon

Alexandra,M., Arthur,W., Van,P. and Derek,M. (2009) Infection with Hymenolepis diminuta Is More Effective than Daily Corticosteroids in Blocking Chemically Induced Colitis in Mice. Journal of Biomedicine and Biotechnology, doi: 10.1155/2010/384523.

MC3T3-E1 Pre-Osteoblasts

Alford,A.I., Terkhorn,S.P., Reddy,A.B. and Hankenson,K.D. (2009) Thrombospondin-2 regulates matrix mineralization in MC3T3-E1 pre-osteoblasts. Bone, doi: 10.1016/j.bone.2009.08.058.

Fibroblast Cells Aramwit,P., Kanokpanont,S., De-Eknamkul,W., Kamei,K. and Srichana,T. (2009) The Effect of Sericin with Variable

Amino-Acid Content from Different Silk Strains on the Production of Collagen and Nitric Oxide. Journal of Biomaterials Science, Polymer Edition, 20, 1295-1306.

Fibroblast Populated Fibrin Gels

Balestrini,J.L. and Billiar,K.L. (2009) Magnitude and Duration of Stretch Modulate Fibroblast Remodeling. Journal of Biomechanical Engineering, 131, 051005.

Osteoblasts

Ball,M.D., O’Connor,D. and Pandit,A. (2009) Use of tissue transglutaminase and fibronectin to influence osteoblast responses to tricalcium phosphate scaffolds. Journal of Materials Science: Materials in Medicine, 20, 113-122.

Murine Lung Tissue Banerjee,E.R., Jiang,Y., Henderson,W.R., Latchman,Y. and Papayannopoulou,T. (2009) Absence of α4 but not ß2

integrins restrains development of chronic allergic asthma using mouse genetic models. Experimental Hematology, 37, 715-727.

Murine Renal Tissue and a Proximal Tubule Epithelial Cell Line (HK-2 Cells)

Bani-Hani,A.H., Leslie,J.A., Asanuma,H., Dinarello,C.A., Campbell,M.T., Meldrum,D.R., Zhang,H., Hile,K. and Meldrum,K.K. (2009) IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney International, 76, 500-511.

Human Fibroblasts

Bendersky,A., Markovits,N. and Bank,I. (2009) Vγ9+ γδT cells in systemic sclerosis patients are numerically and functionally preserved and induce fibroblast apoptosis. Immunobiology, doi: 10.1016/j.imbio.2009.05.012.

Mesenchymal Stem Cells on Chitosan Scaffold

Breyner, N.M., Hell, R.C.R., Carvalho, L.R.P., Machado, C.B., Peixoto Filho, I.N., Valério, P., Pereira, M.M. and Goes, A.M. (2009) Effect of a Three-Dimensional Chitosan Porous Scaffold on the Differentiation of Mesenchymal Stem Cells into Chondrocytes. Cells Tissues Organs, doi: 10.1159/000231472.

NIH 3T3 Fibroblasts

Chen,M., Michaud,H. and Bhowmick,S. (2009) Controlled Vacuum Seeding as a Means of Generating Uniform Cellular Distribution in Electrospun Polycaprolactone (PCL) Scaffolds. Journal of Biomechanical Engineering, 131, 074521.

Human Fibroblasts

Choi,H., Kim,D., Kim,J.W., Ngadiran,S., Sarmidi,M.R. and Park,C.S. (2009) Labisia pumila extract protects skin cells from photoaging caused by UVB irradiation. Journal of Bioscience and Bioengineering, doi: 10.1016/j.biosc.2009.08.478.

Rat Dorsal Tissue Chung,P.S., Shin,J.I., Chang,S.Y. and Ahn,J.C. (2009) Histological Change and Collagen Formation on Laser Wounded

Rat using 808 Diode Laser and CO2 Laser. Science for the Life of Issue 1, 15, 81-86.

Murine Lung Tissue

Couillin,I., Vasseur,V., Charron,S., Gasse,P., Tavernier,M., Guillet,J., Lagente,V., Fick,L., Jacobs,M. and Coelho,F.R. (2009) IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema. The Journal of Immunology, 183, 8195.

Human Mucosal Myofibroblasts

Di Sabatino,A., Jackson,C.L., Pickard,K.M., Buckley,M., Rovedatti,L., Leakey,N.A.B., Picariello,L., Cazzola,P., Monteleone,G. and Tonelli,F. (2009) Transforming growth factor ß signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures. British Medical Journal, 58, 777-789.

Murine Lung Tissue

Du,G., Jin,L., Han,X., Song,Z., Zhang,H. and Liang,W. (2009) Naringenin: A Potential Immunomodulator for Inhibiting Lung Fibrosis and Metastasis. Cancer Research, 69, 3205.

Porcine Bone Marrow-Derived Mesenchymal Cells (bMSCs) Elder,S.H., Cooley Jr,A.J., Borazjani,A., Sowell,B.L., To,H. and Tran,S.C. (2009) Production of Hyaline-like Cartilage by

Bone Marrow Mesenchymal Stem Cells in a Self-Assembly Model. Tissue Engineering Part A, 15, 3025 – 3036.

Murine Lung Tissue

Failla,M., Genovese,T., Mazzon,E., Fruciano,M., Fagone,E., Gili,E., Barera,A., La Rosa,C., Conte,E. and Crimi,N. (2009) 16, 16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection from Bleomycin-Induced Lung Injury and Fibrosis. American Journal of Respiratory Cell and Molecular Biology, 41, 50 – 58.

Skeletal Muscle Construct from C2C12 Myoblast Cell Line

Fujita,H., Shimizu,K. and Nagamori,E. (2009) Novel method for fabrication of skeletal muscle construct from the C2C12 myoblast cell line using serum-free medium AIM-V. Biotechnology and Bioengineering, 103, 1034-1041.

Murine Lung Tissue

Fukumoto,J., Harada,C., Kawaguchi,T., Suetugu,S., Maeyama,T., Inoshima,I., Hamada,N., Kuwano,K. and Nakanishi,Y. (2009) Amphiregulin attenuates bleomycin-induced pneumopathy in mice. American Journal of Physiology- Lung Cellular and Molecular Physiology, doi: 10.1152/ajplung.90576.2008.

Murine Lung Tissue

Gill,S.E., Huizar,I., Bench,E.M., Sussman,S.W., Wang,Y., Khokha,R. and Parks,W.C. (2010) Tissue Inhibitor of Metalloproteinases 3 Regulates Resolution of Inflammation following Acute Lung Injury. American Journal of Pathology, 176, 64-73.

Murine Lung Tissue

Glass,W.G., Argentieri,R.L., Bracht,M., Farrell,F.X., Das,A.M., Del Vecchio,A.M., Hogaboam,C.M. and Murray,L.A.

(2009) Generation of bleomycin-induced lung fibrosis is independent of IL-16. Cytokine, 46, 17–23.

Atherosclerotic Carotid Plaques

Gonçalves,I., Stollenwerk,M.M., Lindholm,M.W., Dias,N., Pedro,L.M., Fernandes,J.F., Moses,J., Fredrikson,G.N., Nilsson,J. and Ares,M.P.S. (2009) Activator protein-1 in carotid plaques is related to cerebrovascular symptoms and cholesteryl ester content. Cardiovascular Pathology, doi: 10.1016/j.carpath.2009.09.003.

Human Bone Marrow Stromal Cells

Green,D.W., Bolland,B.J.R.F., Kanczler,J.M., Lanham,S.A., Walsh,D., Mann,S. and Oreffo,R.O.C. (2009) Augmentation of skeletal tissue formation in impaction bone grafting using vaterite microsphere biocomposites. Biomaterials, 30, 1918-1927.

Murine Colon Tissue

Guan,Q., Ma,Y., Hillman,C.L., Ma,A., Zhou,G., Qing,G. and Peng,Z. (2009) Development of recombinant vaccines against IL-12/IL-23 p40 and in vivo evaluation of their effects in the downregulation of intestinal inflammation in murine colitis. Vaccine, 27, 7096 – 7104.

Articular Cartilages from Human Knee Joint

Han,D.W., Bae,J.Y. and Hyon,S.H. (2009) Biochemical and Histological Evaluations of Articular Cartilages Preserved in Cold Storage Solution Containing Green Tea Catechin, EGCG. Tissue Engineering and Regenerative Medicine, 6, 380-387.

Murine Asthma Model

Hansen,G. (2009) Different role of CD30 in the development of acute and chronic airway inflammation in a murine asthma model. Eur.J.Immunol, 39, 1736-1742.

Bladder Smooth Muscle Cells

Heise,R.L., Ivanova,J., Parekh,A. and Sacks,M.S. (2009) Generating Elastin-Rich Small Intestinal Submucosa-Based Smooth Muscle Constructs Utilizing Exogenous Growth Factors and Cyclic Mechanical Stimulation. Tissue Engineering Part A, 15, 3951-3960.

Rat Renal Tissue

He,L., Qi,Y., Rong,X., Jiang,J., Yang,Q., Yamahara,J., Murray,M. and Li,Y. (2009) The Ayurvedic medicine Salacia oblonga attenuates diabetic renal fibrosis in rats: suppression of angiotensin II/AT1 signaling. Evidence-based Complementary and Alternative Medicine, doi: 10.1093/ecam/nep095.

Murine Lung Mesenchymal Cells and Myofibroblasts

Hecker,L., Vittal,R., Jones,T., Jagirdar,R., Luckhardt,T.R., Horowitz,J.C., Pennathur,S., Martinez,F.J. and Thannickal,V.J. (2009) NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nature Medicine, 15, 1077-1081.

Human Skin Fibroblasts Hemmatazad,H., Rodrigues,H.M., Maurer,B., Brentano,F., Pileckyte,M., Distler,J.H.W., Gay,R.E., Michel,B.A., Gay,S.

and Huber,L.C. (2009) Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis. Arthritis & Rheumatism, 60, 1519-1529.

Rabbit Subcutaneous Implant Model

Henry,J.A., Burugapalli,K., Neuenschwander,P. and Pandit,A. (2009) Structural variants of biodegradable polyesterurethane in vivo evoke a cellular and angiogenic response that is dictated by architecture. Acta Biomaterialia, 5, 29-42.

Rat Cardiac Fibroblasts

Hermida,N., Lopez,B., Gonzalez,A., Dotor,J., Lasarte,J.J., Sarobe,P., Borras-Cuesta,F. and Diez,J. (2009) A synthetic peptide from transforming growth factor-β 1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats. Cardiovascular Research, 81, 601.

Murine Embryonic Fibroblasts and Primary Hepatocytes

Hosui,A., Kimura,A., Yamaji,D., Zhu,B., Na,R. and Hennighausen,L. (2009) Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-ß and STAT3 activation. Journal of Experimental Medicine, doi:10.1084/jem.20080003.

Human Osteoarthritis Cartilage explants and a Rabbit Model of Osteoarthritis

Huh,J.E., Baek,Y.H., Ryu,S.R., Lee,J.D., Choi,D.Y. and Park,D.S. (2009) Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis. International Immunopharmacology, 9, 230-240.

Mouse Osteoclasts

Idris,A.I., Greig,I.R., Bassonga-Landao,E., Ralston,S.H. and van't Hof,R.J. (2009) Identification of Novel Biphenyl Carboxylic Acid Derivatives as Novel Antiresorptive Agents that Do Not Impair Parathyroid Hormone-Induced Bone Formation. Endocrinology, 150, 5-13.

Human Term Fetal Membranes

Jabareen,M., Mallik,A.S., Bilic,G., Zisch,A.H. and Mazza,E. (2009) Relation between mechanical properties and microstructure of human fetal membranes: An attempt towards a quantitative analysis. European Journal of Obstetrics and Gynecology, 144, 134-141.

Murine Lung Tissue

Kakizaki,T., Kohno,M., Watanabe,M., Tajima,A., Izumi,Y., Miyasho,T., Tasaka,S., Fukunaga,K., Maruyama,I. and Ishizaka,A. (2009) Exacerbation of Bleomycin-Induced Injury and Fibrosis by Pneumonectomy in the Residual Lung of Mice. Journal of Surgical Research, 154, 336-344.

Murine Lung Tissue

Kanda,A., Driss,V., Hornez,N., Abdallah,M., Roumier,T., Abboud,G., Legrand,F., Staumont-SalléD., Quéant,S. and Bertout,J. (2009) Eosinophil-derived IFN- induces airway hyperresponsiveness and lung inflammation in the absence of lymphocytes. The Journal of Allergy and Clinical Immunology, 124, 573-582.

Rat Renal Tissue and Cultured Mesangial Cells

Kang,Y.S., Ko,G.J., Lee,M.H., Song,H.K., Han,S.Y., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2009) Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrology Dialysis Transplantation, 24, 73-84.

Murine Skin Tissue

Kanno,Y., Kawashita,E., Minamida,M., Kaneiwa,A., Okada,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2009) α2-Antiplasmin Is Associated with the Progression of Fibrosis. American Journal of Pathology, doi: 10.2353/ajpath.2010.090150.

Human Dermal Fibroblasts

Kim,H.J., Song,S.B., Lee,J.Y., Cho,B.K., Cho,D.H. and Park,H.J. (2009) Interleukin-18 Downregulates Collagen Production in Human Dermal Fibroblasts via ERK pathway. The Journal of Immunology, 182, 98-14.

Rat Ear Fibroblast Cells

Kim, J.-H. and Choi, J.-Y. (2009) Study on thermosensitivity of chitosan scaffold and on its effects on fibroblast proliferation in cell therapy for soft tissue augmentation. J. Kor. Oral Maxillofac. Surg., 35, 146-152.

Rat Common Bile Duct Fibroblasts

Kim,T.H., Moon,J.H., Savard,C.E., Kuver,R. and Lee,S.P. (2009) Effects of lipopolysaccharide on platelet-derived growth factor isoform and receptor expression in cultured rat common bile duct fibroblasts and cholangiocytes. Journal of Gastroenterology and Hepatology, 24, 1218-1225.

Osteoblastic MC3T3-E1 Cells

Kim,Y.H. and Choi,E.M. (2009) Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract. Phytotherapy Research, 23, 737-739.

Immobilised Matrix Vesicle Model

Kinugawa,M., Fukuzawa,S. and Tachibana,K. (2009) Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine. Journal of Bone and Mineral Metabolism, 27, 303-314.

Mouse and Human Lung Fibroblasts

Königshoff,M., Kramer,M., Balsara,N., Wilhelm,J., Amarie,O.V., Jahn,A., Rose,F., Fink,L., Seeger,W. and Schaefer,L. (2009) WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. The Journal of Clinical Investigation, 119, 772-787.

Murine Bone Marrow Mesenchymal Stem Cells

Kumamoto,M., Nishiwaki,T., Matsuo,N., Kimura,H. and Matsushima,K. (2009) Minimally-cultured Bone Marrow mesenchymal stem cells ameliorate fibrotic lung injury. European Respiratory Journal, doi:10.1183/ 09031936-00128508.

Mouse Breast Cell Line Lee,C.G., Hartl,D., Lee,G.R., Koller,B., Matsuura,H., Da Silva,C.A., Sohn,M.H., Cohn,L., Homer,R.J. and Kozhich,A.A.

(2009) Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. Journal of Experimental Medicine, 206, 1149-1166.

Chondrocytes Lee,N.K., Oh,H.J., Hong,C.M., Suh,H. and Hong,S.H. (2009) Comparison of the synthetic biodegradable polymers,

polylactide (PLA), and polylactic-co-glycolic acid (PLGA) as scaffolds for artificial cartilage. Biotechnology and Bioprocess Engineering, 14, 180-186.

Murine Lung Tissue

Lee,J., Reddy,R., Barsky,L., Scholes,J., Chen,H., Shi,W. and Driscoll,B. (2009) Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. American Journal of Physiology- Lung Cellular and Molecular Physiology, 296, L57.


Lefler,A. and Ghanem,A. (2009) Development of bFGF-Chitosan Matrices and Their Interactions with Human Dermal Fibroblast Cells. Journal of Biomaterials Science, Polymer Edition, 20, 1335-1351.

Connective Tissue and Fibroblasts

Lin,Y.K. and Kuan,C.Y. (2009) Development of 4-hydroxyproline analysis kit and its application to collagen quantification. Food Chemistry, doi: 10.1016/j.foodchem.2009.08.009.

Rat Hepatic Stellate Cells

Lin,Y.L., Lin,C.Y., Chi,C.W. and Huang,Y.T. (2009) Study on antifibrotic effects of curcumin in rat hepatic stellate cells. Phytotherapy Research, 23, 927-932.

Rat Hepatic Stellate Cell Line (HSC-T6)

Lin,Y.L., Wu,C.F. and Huang,Y.T. (2009) Effects of rhubarb on migration of rat hepatic stellate cells. Journal of Gastroenterology and Hepatology, 24, 453-461.

Human Myocardium

Lopez,B., Querejeta,R., Gonzalez,A., Beaumont,J., Larman,M. and Diez,J. (2009) Impact of Treatment on Myocardial Lysyl Oxidase Expression and Collagen Cross-Linking in Patients With Heart Failure. Hypertension, 53, 236-242.

Osteoblastic Cell Cultures

Lozano,D., Manzano,M., Doadrio,J.C., Salinas,A.J., Vallet-RegíM., Gómez-Barrena,E. and Esbrit,P. (2009) Osteostatin-loaded bioceramics stimulate osteoblastic growth and differentiation. Acta Biomaterialia, doi: 10.1016/j.actbio.2009.08.033.

Bone Marrow Cultures and Osteoblastic MC3T3-E1 Cells

Lozano,D., de Castro,L.F., Dapía,S., Andrade-Zapata,I., Manzarbeitia,F., Ayvarez-Arroyo,M., Gómez-Barrena,E. and Esbrit,P. (2009) Role of Parathyroid Hormone-Related Protein in the Decreased Osteoblast Function in Diabetes-Related Osteopenia. Endocrinology, 150, 2027-2035.

Murine Lung Tissue

Manicone,A.M., Huizar,I. and McGuire,J.K. (2009) Matrilysin (Matrix Metalloproteinase-7) Regulates Anti-Inflammatory and Antifibrotic Pulmonary Dendritic Cells That Express CD103 αE ß7-Integrin). American Journal of Pathology, 175, 2319 – 2331.

Murine Lung Tissue

Markart,P., Luboeinski,T., Korfei,M., Schmidt,R., Wygrecka,M., Mahavadi,P., Mayer,K., Wilhelm,J., Seeger,W. and Guenther,A. (2009) Alveolar Oxidative Stress is Associated with Elevated Levels of Nonenzymatic Low-Molecular-Weight Antioxidants in Patients with Different Forms of Chronic Fibrosing Interstitial Lung Diseases. Antioxidants & Redox Signaling, 11, 227-240.

Human Fibrocytes

Mehrad,B., Burdick,M.D. and Strieter,R.M. (2009) Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis. International Journal of Biochemistry and Cell Biology, 41, 1708-1718.

Human Retinal Pigment (ARPE-19) Cell Line

Morales,S.A., Mareninov,S., Wadehra,M., Zhang,L., Goodglick,L., Braun,J. and Gordon,L.K. (2009) FAK Activation and the Role of Epithelial Membrane Protein 2 (EMP2) in Collagen Gel Contraction. Investigative Ophthalmology & Visual Science, 50, 462-469.

EpiDerm FT Engineered Skin, Murine Epidermal Cells (JB6 P+) and Immune-Competent Hairless SKH-1 Mice

Murray,A.R., Kisin,E., Leonard,S.S., Young,S.H., Kommineni,C., Kagan,V.E., Castranova,V. and Shvedova,A.A. (2009) Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology, 257, 161-171.

Murine Peritoneal Fibroblasts

Nakav,S., Kachko,L., Vorobiov,M., Rogachev,B., Chaimovitz,C., Zlotnik,M. and Douvdevani,A. (2009) Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models. Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfp041.

Bovine Chondrocytes Seeded in Non-Adherent Agarose Molds

Natoli,R.M., Revell,C.M. and Athanasiou,K.A. (2009) Chondroitinase ABC Treatment Results in Increased Tensile Properties of Self-Assembled Tissue Engineered Articular Cartilage. Tissue Engineering.Part A, 15, 3119 – 3128.

Murine Lung Tissue

Nicola,T., Hagood,J.S., James,M.L., MacEwen,M.W., Williams,T.A., Hewitt,M.M., Schwiebert,L., Bulger,A., Oparil,S. and Chen,Y.F. (2009) Loss of Thy-1 inhibits alveolar development in the newborn mouse lung. American Journal of Physiology- Lung Cellular and Molecular Physiology, 296, L738-L750.

Murine Lung Tissue Niese,K.A., Collier,A.R., Hajek,A.R., Cederbaum,S.D., O'Brien,W.E., Wills-Karp,M., Rothenberg,M.E. and

Zimmermann,N. (2009) Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunology, 10, 33.

Murine Lung Fibroblasts

Oga,T., Matsuoka,T., Yao,C., Nonomura,K., Kitaoka,S., Sakata,D., Kita,Y., Tanizawa,K., Taguchi,Y. and Chin,K. (2009) Prostaglandin F2 αreceptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-ß. Nature medicine, 15, 1426-1430.

Human Lung Fibroblasts

Okada,M., Suzuki,K., Matsumoto,M., Takada,K., Nakanishi,T., Horikoshi,H., Higuchi,T., Hosono,Y., Nakayama,M. and Ohsuzu,F. (2009) Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and matrix proteins in human lung fibroblasts. Journal of Clinical Pharmacy & Therapeutics, 34, 289-299.

Rat Calvariae Osteoblasts

Orriss,I.R., Key,M.L., Colston,K.W. and Arnett,T.R. (2009) Inhibition of osteoblast function in vitro by aminobisphosphonates. Journal of Cellular Biochemistry, 106, 109-118.

Swiss Mouse Intraplantar Region

Pareja-Santos,A., Saraiva,T.C., Costa,E.P., Santos,M.F., Zorn,T.T., Souza,V.M.O., Lopes-Ferreira,M. and Lima,C. (2009) Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular matrix degradation. International Journal of Experimental Pathology, 90, 34-43.


Park,H.J., Cho,D.H., Kim,H.J., Lee,J.Y., Cho,B.K., Bang,S.I., Song,S.Y., Yamasaki,K., Di Nardo,A. and Gallo,R.L. (2009) Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. The Journal of investigative dermatology, 129, 843-850.

Rat Respiratory Tract

Pauluhn,J. (2009) Subchronic 13-week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects are determined by Density of Agglomerate Structures, not fibrillar Structures. Toxicological Sciences, doi: 10.1093/toxsci/kfp247.

Tissue Engineered Valve Constructs Seeded With Mesenchymal Stem Cells

Ramaswamy,S., Gottlieb,D., Engelmayr,G.C., Aikawa,E., Schmidt,D.E., Gaitan-Leon,D.M., Sales,V.L., Mayer,J.E. and Sacks,M.S. (2010) The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials, 31, 1114-1125.

Murine Lung Tissue

Ryman-Rasmussen,J.P., Tewksbury,E.W., Moss,O.R., Cesta,M.F., Wong,B.A. and Bonner,J.C. (2009) Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. American Journal of Respiratory Cell and Molecular Biology, 40, 349-358.

Dermal Fibroblasts

Saesoo,S., Sramala,I., Soottitantawat,A., Charinpanitkul,T. and Ruktanonchai,U.R. (2009) Enhanced stability and in vitro bioactivity of surfactant-loaded liposomes containing Asiatic Pennywort extract. Journal of Microencapsulation, doi: 10.3109/02652040903447686.

Ovine Peripheral Blood Endothelial Progenitor Cells

Sales,V.L., Mettler,B.A., Engelmayr Jr,G.C., Aikawa,E., Bischoff,J., Martin,D.P., Exarhopoulos,A., Moses,M.A., Schoen,F.J. and Sacks,M.S. (2009) Endothelial Progenitor Cells as a Sole Source for Ex Vivo Seeding of Tissue-Engineered Heart Valves. Tissue Engineering Part A, doi: 10.1089/ten.tea.2009.0424.

Human Heart Valves

Schenke-Layland,K., Stock,U.A., Nsair,A., Xie,J., Angelis,E., Fonseca,C.G., Larbig,R., Mahajan,A., Shivkumar,K., Fishbein,M.C. and MacLellan, W.R. (2009) Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix. European Heart Journal, 30, 2254-2265.

Human Foreskin Fibroblasts

Schenke-Layland,K., Rofail,F., Heydarkhan,S., Gluck,J.M., Ingle,N.P., Angelis,E., Choi,C.H., MacLellan,W.R., Beygui,R.E. and Shemin,R.J. (2009) The use of three-dimensional nanostructures to instruct cells to produce extracellular matrix for regenerative medicine strategies. Biomaterials, 30, 4665-4675.

Mesenchymal Stem Cells

Schnabel,L.V., Lynch,M.E., van der Meulen,M.C.H., Yeager,A.E., Kornatowski,M.A. and Nixon,A.J. (2009) Mesenchymal stem cells and insulin-like growth factor-I gene-enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons. Journal of Orthopaedic Research, 27, 1392-1398.

Murine Airways

Schneider,D.J., Lindsay,J.C., Zhou,Y., Molina,J.G. and Blackburn,M.R. (2009) Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease. The FASEB Journal, doi: 10.1096/fj.09-140772.

Anterior Cruciatge Ligament Cell and T-Lymophocytes on Composite Silk Scaffolds

Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S. and Park,J.K. (2009) Increase in cell migration and angiogenesis in a composite silk scaffold for tissue-engineered ligaments. Journal of Orthopaedic Research, 27, 495-503.

Murine Skin and Lung Tissue

Servettaz,A., Goulvestre,C., Kavian,N., Nicco,C., Guilpain,P., Chereau,C., Vuiblet,V., Guillevin,L., Mouthon,L. and Weill,B. (2009) Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse. The Journal of Immunology, 182, 5855-5864.

Murine Conjunctival Tissue

Shii,D., Nakagawa,S., Shinomiya,K., Yoshimi,M., Katsuta,O., Oda,T. and Nakamura,M. (2009) Cyclosporin A Eye Drops Inhibit Fibrosis and Inflammatory Cell Infiltration in Murine Type I Allergic Conjunctivitis without Affecting the Early-Phase Reaction. Current Eye Research, 34, 426-437.

Smooth Muscle Cells

Shin,J.W., Lee,Y.J., Heo,S.J., Park,S.A., Kim,S.H., Kim,Y.J., Kim,D.H. and Shin,J.W. (2009) Manufacturing of Multi-Layered Nanofibrous Structures Composed of Polyurethane and Poly (ethylene oxide) as Potential Blood Vessel Scaffolds. Journal of Biomaterials Science, Polymer Edition, 20, 5, 757-771.

Rat Myogenic Cells from Large Thigh Muscle

Stern,M.M., Myers,R.L., Hammam,N., Stern,K.A., Eberli,D., Kritchevsky,S.B., Soker,S. and Van Dyke,M. (2009) The influence of extracellular matrix derived from skeletal muscle tissue on the proliferation and differentiation of myogenic progenitor cells ex vivo. Biomaterials, 30, 2393-2399.

Mesenchymal Progenitor Cells (Fibrocytes)

Strieter,R.M., Keeley,E.C., Hughes,M.A., Burdick,M.D. and Mehrad,B. (2009) The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. Journal of leukocyte biology, 86, 1111-1118.

Mouse Osteoblastic Cell Line (MC3T3-E1)

Suh,K.S., Choi,E.M., Kwon,M., Chon,S., Oh,S., Woo,J.T., Kim,S.W., Kim,J.W. and Kim,Y.S. (2009) Kaempferol Attenuates 2-Deoxy-D-ribose-Induced Oxidative Cell Damage in MC3T3-E1 Osteoblastic Cells. Biological & Pharmaceutical Bulletin, 32, 746-749.

Rat Pancreatic Tissue

Suzuki,N., Masamune,A., Kikuta,K., Watanabe,T., Satoh,K. and Shimosegawa,T. (2009) Ellagic Acid Inhibits Pancreatic Fibrosis in Male Wistar Bonn/Kobori Rats. Digestive Diseases and Sciences, 54, 802-810.

Murine Patellar Tendons

Szczodry,M., Zhang,J., Lim,C., Davitt,H.L., Yeager,T., Fu,F.H. and Wang,J.H.C. (2009) Treadmill running exercise results in the presence of numerous myofibroblasts in mouse patellar tendons. Journal of Orthopaedic Research, 27, 1373-1378.

Human Embryonic Stem Cells (hESCs) Toh,W.S., Guo,X-M., Choo,A.B., Lu,K., Lee,E.H. and Cao,T. (2009) Differentiation and Enrichment of Expandable

Chondrogenic Cells from Human Embryonic Stem Cells in Vitro. Journal of Cellular and Molecular Medicine, doi:10.1111/j.1582-4934.2009.00762.x.

Murine Hepatic Tissue

Tong,Z.Y., Chen,R., Alt,D.S., Kemper,S., Perbal,B. and Brigstock,D.R. (2009) Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes. Hepatology, 50, 939-947.

Rat Liver Tissue Tsai,P.C., Fu,T.W., Chen,Y.M.A., Ko,T.L., Chen,T.H., Shih,Y.H., Hung,S.C. and Fu,Y.S. (2009) The therapeutic

potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis. Liver Transplantation, 15, 484-495.

Rat Glomeruli and Cultured Mesangial Cells

Urushihara,M., Takamatsu,M., Shimizu,M., Kondo,S., Kinoshita,Y., Suga,K., Kitamura,A., Matsuura,S., Yoshizumi,M. and Tamaki,T. (2009) ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis. American Journal of Physiology- Renal Physiology, doi: 10.1152/ajprenal.00124.2009.

Primary Human Cardiac Fibroblasts Venkatachalam,K., Venkatesan,B., Valente,A.J., Melby,P.C., Nandish,S., Reusch,J.E.B., Clark,R.A. and

Chandrasekar,B. (2009) Wisp1, a pro-mitogenic, pro-survival factor, mediates TNF-alpha stimulated cardiac fibroblast proliferation, but inhibits TNF-alpha-induced cardiomyocyte death. Journal of Biological Chemistry, 284, 14414-14427.

Murine Diaphragm Vetrone,S.A., Montecino-Rodriguez,E., Kudryashova,E., Kramerova,I., Hoffman,E.P., Liu,S.D., Miceli,M.C. and

Spencer,M.J. (2009) Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-ß. The Journal of Clinical Investigation, 119, 1583-1594.

Human Palmar Fascia Cells

Vi,L., Njarlangattil,A., Wu,Y., Gan,B.S. and O'Gorman,D.B. (2009) Type-1 collagen differentially alters beta-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells. BMC Musculoskeletal Disorders, 10, 72.

Human Palmar Fascia Cells

Vi,L., Feng,L., Zhu,R.D., Wu,Y., Satish,L., Gan,B.S. and O'Gorman,D.B. (2009) Periostin differentially induces proliferation, contraction and apoptosis of primary Dupuytren's disease and adjacent palmar fascia cells. Experimental Cell Research, 315, 3574 – 3586.

Human Smooth Muscle Cells

Wang,C., Cen,L., Yin,S., Liu,Q., Liu,W., Cao,Y. and Cui,L. (2010) A small diameter elastic blood vessel wall prepared under pulsatile conditions from polyglycolic acid mesh and smooth muscle cells differentiated from adipose-derived stem cells. Biomaterials, 31, 621-630.

Murine Colonic Fibroblast Cells

Wang,H., Zhang,R., Wen,S., McCafferty,D.M., Beck,P.L. and MacNaughton,W.K. (2009) Nitric oxide increases Wnt-induced secreted protein-1 (WISP-1/CCN4) expression and function in colitis. Journal of Molecular Medicine, 87, 435-445.

Murine Calf Muscle

Watanuki,M., Kishimoto,K.N., Kotajima,S., Iwabuchi,S. and Kokubun,S. (2009) Effect of low-intensity pulsed ultrasound on scaffold-free ectopic bone formation in skeletal muscle. Upsala Journal of Medical Sciences, 114, 242-248.

Rat Stellate Liver Cell Line (HSC-T6)

Weng,T.C., Shen,C.C., Chiu,Y.T., Lin,Y.L., Kuo,C.D. and Huang,Y.T. (2009) Inhibitory effects of armepavine against hepatic fibrosis in rats. Journal of Biomedical Science, 16, 78.

Murine Lung Tissue

Wigenstam,E., Rocksén,D., Ekstrand-Hammarström,B. and Bucht,A. (2009) Treatment with dexamethasone or liposome-encapsuled vitamin E provides beneficial effects after chemical-induced lung injury. Inhalation Toxicology, 11, 958-964.

Murine Skin and Lung Tissue

Wu,M., Melichian,D.S., de la Garza,M., Gruner,K., Bhattacharyya,S., Barr,L., Nair,A., Shahrara,S., Sporn,P.H.S. and Mustoe,T.A. (2009) Essential Roles for Early Growth Response Transcription Factor Egr-1 in Tissue Fibrosis and Wound Healing. American Journal of Pathology, 175, 1041.

Murine Model of Scleroderma

Wu,M., Melichian,D.S., Chang,E., Warner-Blankenship,M., Ghosh,A.K. and Varga,J. (2009) Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γ. American Journal of Pathology, 174, 519.

Rat Liver Tissue

Yasoshima,M., Sato,Y., Furubo,S., Kizawa,K., Sanzen,T., Ozaki,S., Harada,K. and Nakanuma,Y. (2009) Matrix proteins of basement membrane of intrahepatic bile ducts are degraded in congenital hepatic fibrosis and Caroli's disease No conflicts of interest were declared. The Journal of Pathology, 217, 442-451.

Porcine Hind Leg Tibial Osteochondral Explants

Yeow,C.H., Lau,S.T., Lee,P.V.S. and Goh,J.C.H. (2009) Damage and degenerative changes in menisci-covered and exposed tibial osteochondral regions after simulated landing impact compression-a porcine study. Journal of Orthopaedic Research, 27, 1100-1108.

Equine Tendon Tissue

Young,N.J., Becker,D.L., Fleck,R.A., Goodship,A.E. and Patterson-Kane,J.C. (2009) Maturational alterations in gap junction expression and associated collagen synthesis in response to tendon function. Matrix Biology, 28, 311-323.

Mouse Embryonic Fibroblast Cell Line (NIH 3T3) Zhang,W., Rong,J., Wang,Q. and He,X. (2009) The encapsulation and intracellular delivery of trehalose using a

thermally responsive nanocapsule. Nanotechnology, 20, 275101.

Mouse Model of Atopic Dermatitis

Zheng,T., Oh,M., Oh,S., Wu,F., Myers,A. and Zhu,Z. (2009) IL-13 Regulation of Skin Remodeling in a Mouse Model of Atopic Dermatitis. The Journal of Allergy and Clinical Immunology, 123, 35.

Murine Lung Tissue Zhou,Y., Mohsenin,A., Morschl,E., Young,H.W.J., Molina,J.G., Ma,W., Sun,C.X., Martinez-Valdez,H. and Blackburn,M.R.

(2009) Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A2B Adenosine Receptor. The Journal of Immunology, 182, 8037-8046.

2008

Mouse Model of Dermal Fibrosis Akhmetshina,A., Dees,C., Pileckyte,M., Maurer,B., Axmann,R., Jungel,A., Zwerina,J., Gay,S., Schett,G. and Distler,O.

(2008) Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis. The FASEB Journal, 22, 2214-2222.

Scleroderma Fibroblasts

Akhmetshina,A., Dees,C., Pileckyte,M., Szucs,G., Spriewald,B.M., Zwerina,J., Distler,O., Schett,G. and Distler,J.H. (2008) Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts. Arthritis Rheum, 58, 2553-2564.

Rabbit Bone Marrow Cells Seeded on Porcine Small Intestine Submucosa

Almarza,A.J., Yang,G., Woo,S.L.Y., Nguyen,T. and Abramowitch,S.D. (2008) Positive Changes in Bone Marrow-Derived Cells in Response to Culture on an Aligned Bioscaffold. Tissue Engineering, 14, 1489-1495.


Antao-Menezes,A., Turpin,E.A., Bost,P.C., Ryman-Rasmussen,J.P. and Bonner,J.C. (2008) STAT-1 Signaling in Human Lung Fibroblasts Is Induced by Vanadium Pentoxide through an IFN-beta Autocrine Loop. The Journal of Immunology, 180, 4200-4207.

Cultured Human Intrahepatic (Myo) Fibroblasts (hIHFs)

Aoudjehane,L., Pissaia,A., Scatton,O., Podevin,P., Massault,P.P., Chouzenoux,S., Soubrane,O., Calmus,Y. and Conti,F. (2008) Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway. Laboratory Investigation, 88, 973-985.


Bhogal, R.K. and Bona, C.A. (2008) Regulatory Effect of Extracellular Signal- Regulated Kinases (ERK) on Type I Collagen Synthesis in Human Dermal Fibroblasts Stimulated by IL-4 and IL-13. International Reviews of Immunology, 27, 472 – 496.

Porcine Valvular Interstitial Cells from Various Regions of the Mitral Valve

Blevins,T.L., Peterson,S.B., Lee,E.L., Bailey,A.M., Frederick,J.D., Huynh,T.N., Gupta,V. and Grande-Allen,K. (2008) Mitral Valvular Interstitial Cells Demonstrate Regional, Adhesional, and Synthetic Heterogeneity. Cells Tissues Organs, 187, 113-122.

Human Lung Fibroblasts and Mouse Bleomycin Induced Lung Fibrosis

Borie,R., Fabre,A., Prost,F., Marchal-Somme,J., Lebtahi,R., Marchand-Adam,S., Aubier,M., Soler,P. and Crestani,B. (2008) Activation of somatostatin receptors attenuates pulmonary fibrosis. Thorax, 63, 251-258.

An Alloxan Rabbit Ear Ulcer Model

Breen,A.M., Dockery,P., O'Brien,T. and Pandit,A.S. (2008) The use of therapeutic gene eNOS delivered via a fibrin scaffold enhances wound healing in a compromised wound model. Biomaterials, 29, 3143-3151.

Polycarbonate Track-Etched Membranes

Bueno,E.M. and Ruberti,J.W. (2008) Optimizing collagen transport through track-etched nanopores. Journal of Membrane Science, 321, 250-263.


Caraci,F., Gili,E., Calafiore,M., Failla,M., La Rosa,C., Crimi,N., Sortino,M.A., Nicoletti,F., Copani,A. and Vancheri,C. (2008) TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts. Pharmacological Research, 57, 274-282.

Fetal Rat Lung Tissue

Chen,C.M., Chou,H.C., Wang,L.F. and Lang,Y.D. (2008) Experimental Oligohydramnios Decreases Collagen in Hypoplastic Fetal Rat Lungs. Experimental Biology and Medicine, 233, 1334-1340.

Rabbit Digitorum Extensor Tendon

Chen,C.H., Liu,H.W., Tsai,C.L., Yu,C.M. and Lin,I. (2008) Photoencapsulation of Bone Morphogenetic Protein-2 and Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel. The American Journal of Sports Medicine, 36, 461-473.

Murine Osteoblastic MC3T3-E1 Cells

Choi,E.M. and Kim,Y.H. (2008) Hesperetin attenuates the highly reducing sugar-triggered inhibition of osteoblast differentiation. Cell Biology and Toxicology, 24, 225-231.

Bone Marrow Derived Mesenchymal Stem Cells (MSCs)

Choi,K.M., Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S. and Park,J.K. (2008) Effect of ascorbic acid on bone marrow-derived mesenchymal stem cell proliferation and differentiation. Journal of Bioscience and Bioengineering, 105, 586-594.

Rabbit Autologous Cells from Vaginal Biopsy

De Philippo,R.E., Bishop,C.E., Freitas Filho,L., Yoo,J.J. and Atala,A. (2008) Tissue Engineering a Complete Vaginal Replacement From a Small Biopsy of Autologous Tissue. Transplantation, 86, 208-214.

Human Fibroblasts from Systemic Sclerotic Patients

Distler,J.H.W., Akhmetshina,A., Schett,G. and Distler,O. (2008) Monocyte chemoattractant proteins in the pathogenesis of systemic sclerosis. Rheumatology, 48, 98-103.

Atherosclerotic Lesions in Apo-E-Deficient Mice

Do,G.M., Kwon,E.Y., Kim,H.J., Jeon,S.M., Ha,T.Y., Park,T. and Choi,M.S. (2008) Long-term effects of resveratrol supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient mice. Biochemical and Biophysical Research Communications, 374, 55-59.

Rat Lung Tissue

Elgrabli,D., bella-Gallart,S., Robidel,F., Rogerieux,F., Boczkowski,J. and Lacroix,G. (2008) Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes. Toxicology, 253, 131-136.

Murine Lung Tissue

Fabre,A., Marchal-Somme,J., Marchand-Adam,S., Quesnel,C., Borie,R., Dehoux,M., Ruffie,C., Callebert,J., Launay,J.M. and Henin,D. (2008) Modulation of bleomycin induced lung fibrosis by serotonin receptor antagonists in mice. European Respiratory Journal, doi:10.1183/09031936-00126907.

Murine Lung Tissue

Failla,M., Genovese,T., Mazzon,E., Fruciano,M., Fagone,E., Gili,E., Barera,A., La Rosa,C., Conte,E., Crimi,N., Cuzzocrea, S. and Vaneheri, C. (2008) 16, 16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection from Bleomycin-induced Lung Injury and Fibrosis. American Journal of Respiratory Cell and Molecular Biology, doi:10.1165/rcmb.2007-04380C.

Mesenchymal Stem Cells

Fan,H., Liu,H., Toh,S.L. and Goh,J.C.H. (2008) Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold. Biomaterials, 29, 1017-1027.

Mesenchymal Stem Cells and Silk Scaffold

Fan,H., Liu,H., Wong,E.J.W., Toh,S.L. and Goh,J.C.H. (2008) In vivo study of anterior cruciate ligament regeneration using mesenchymal stem cells and silk scaffold. Biomaterials, 29, 3324-3337.

Murine Intestinal Myofibroblasts

Fichtner-Feigl,S., Young,C.A., Kitani,A., Geissler,E.K., Schlitt,H.J. and Strober,W. (2008) IL-13 Signaling via IL-13Ra2 Induces Major Downstream Fibrogenic Factors Mediating Fibrosis in Chronic TNBS Colitis. Gastroenterology, 135, 2003-2013.e7.

Bone Marrow Samples

Freyman, T. (2008) Decellularized bone marrow extracellular matrix. US Patent 7326571.

Cartilage Tissue

Furukawa,K.S., Imura,K., Tateishi,T. and Ushida,T. (2008) Scaffold-free cartilage by rotational culture for tissue engineering. Journal of Biotechnology, 133, 134-145.

Collagen Based Scaffolds

Garcia,Y., Wilkins,B., Collighan,R.J., Griffin,M. and Pandit,A. (2008) Towards development of a dermal rudiment for enhanced wound healing response. Biomaterials, 29, 857-868.

Hepatic Stellate Cells

Gardi,C., Arezzini,B., Monaco,B., De Montis,M.G., Vecchio,D. and Comporti,M. (2008) F 2-isoprostane receptors on hepatic stellate cells. Laboratory Investigation, 88, 124-131.

ECM Model of Fibroblast Monolayer and Endothelial Cell-Coated Beads

Ghajar,C.M., Chen,X., Harris,J.W., Suresh,V., Hughes,C.C.W., Jeon,N.L., Putnam,A.J. and George,S.C. (2008) The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis. Biophysical Journal, 94, 1930-1941.

Human Carotid Plaques

Gonçalves, I., Ares, M.P.S., Moberg, A., Moses, J., To, F., Montan, J., Pedro, L.M., Dias, N., e Fernandes, J.F., Fredrikson, G.N., Nilsson, J., Jovinge, S. and Bengtsson, E. (2008) Elastin- and Collagen-Rich Human Carotid Plaques Have Increased Levels of the Cysteine Protease Inhibitor Cystatin C. Journal of Vascular Research, 45, 395 – 401.

Murine Intestinal Tissue

Grassl,G.A., Valdez,Y., Bergstrom,K.S.B., Vallance,B.A. and Finlay,B.B. (2008) Chronic Enteric Salmonella Infection in Mice Leads to Severe and Persistent Intestinal Fibrosis. Gastroenterology, 134,768-780.e2.

293 T-Rex Cell Line

Greenspan,D., Zhang,Y. and GE,G. (2008) Method and composition for treating a fibrotic disorder. WIPO Patent Application WO/2008/024767.

Porcine Valvular Interstitial Cells from Distinct Regions of Mitral Valve

Gupta,V., Werdenberg,J.A., Mendez,J.S. and Jane Grande-Allen,K. (2008) Influence of strain on proteoglycan synthesis by valvular interstitial cells in three-dimensional culture. Acta Biomaterialia, 4, 88-96.

Porcine Valvular Interstitial Cells from Valve Leaflet and Chordae

Gupta,V., Werdenberg,J.A., Lawrence,B.D., Mendez,J.S., Stephens,E.H. and Grande-Allen,K.J. (2008) Reversible Secretion of Glycosaminoglycans and Proteoglycans by Cyclically Stretched Valvular Cells in 3D Culture. Annals of Biomedical Engineering, 36, 1092-1103.

Demineralized Bone Matrix

Han,B., Yang,Z. and Nimni,M. (2008) Effects of gamma irradiation on osteoinduction associated with demineralized bone matrix. Journal of Orthopaedic Research, 26, 75-82.

Murine Lung Tissue

Hardie,W.D., Davidson,C., Ikegami,M., Leikauf,G.D., Le Cras,T.D., Prestridge,A., Whitsett,J.A. and Korfhagen,T.R. (2008) EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-α-induced pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L1217-L1225.

Rabbit Fibrocartilaginous Tissues

Hashem,G., Zhang,Q., Hayami,T., Chen,J., Wang,W. and Kapila,S. (2008) Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis Research and Therapy, 8, R98.

Murine Lung Tissue

Hashimoto,S., Amaya,F., Matsuyama,H., Ueno,H., Kikuchi,S., Tanaka,M., Watanabe,Y., Ebina,M., Ishizaka,A. and Tsukita,S. (2008) Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L566-L574.

Human Annulus Fibrosus (HAF) Cells

Helen,W. and Gough,J.E. (2008) Cell viability, proliferation and extracellular matrix production of human annulus fibrosus cells cultured within PDLLA/Bioglass® composite foam scaffolds in vitro. Acta Biomaterialia, 4, 230-243.

Murine Lung Tissue

Hirata,H., Arima,M., Fukushima,Y., Ishii,Y., Tokuhisa,T. and Fukuda,T. (2008) Effects of Th2 pulmonary inflammation in mice with bleomycin-induced pulmonary fibrosis. Respirology, 13, 788-798.

Murine Liver Tissue

Hisamori,S., Tabata,C., Kadokawa,Y., Okoshi,K., Tabata,R., Mori,A., Nagayama,S., Watanabe,G., Kubo,H. and Sakai,Y. (2008) All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production. Liver International, 28, 1217-1225.

Rat Mesenchymal Stem Cells and Porcine Aortic Valve Leaflets.

Hong,H., Dong,G.N., Shi,W.J., Chen,S., Guo,C. and Hu,P. (2008) Fabrication of Biomatrix/Polymer Hybrid Scaffold for Heart Valve Tissue Engineering in Vitro. ASAIO Journal, 54, 627-632.

Murine Dorsum

Hong,H.J., Jin,S.E., Park,J.S., Ahn,W.S. and Kim,C.K. (2008) Accelerated wound healing by smad3 antisense oligonucleotides-impregnated chitosan/alginate polyelectrolyte complex. Biomaterials, 29, 4831-4837.

Mouse Model of Scleroderma

Hoyles,R.K., Khan,K., Shiwen,X., Howat,S.L., Lindahl,G.E., Leoni,P., du Bois,R.M., Wells,A.U., Black,C.M. and Abraham,D.J. (2008) Fibroblast-Specific Perturbation of Transforming Growth Factor Signaling Provides Insight Into Potential Pathogenic Mechanisms of Scleroderma-Associated Lung Fibrosis. Arthritis & Rheumatism, 58, 1175-1188.

Mouse Cardiac Fibroblasts

Hu,C., Dandapat,A., Sun,L., Khan,J.A., Liu,Y., Hermonat,P.L. and Mehta,J.L. (2008) Regulation of TGF β1-mediated Collagen Formation by LOX-1: Studies Based on Forced Overexpression of TGF β1 in Wild-Type and LOX-1 Knock-Out Mouse Cardiac Fibroblasts. Journal of Biological Chemistry, 283, 10226-10231.

Human Cartilage Culture and a Rabbit Model of Osteoarthritis

Huh,J.E., Baek,Y.H., Ryu,S.R., Lee,J.D., Choi,D.Y. and Park,D.S. (2008) Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis. International Immunopharmacology, 9, 230-240.

Osteoblasts In Vitro and Calvarial Osteoblasts In Vivo

Idris,A.I., Rojas,J., Greig,I.R., van’t Hof,R.J. and Ralston,S.H. (2008) Aminobisphosphonates Cause Osteoblast Apoptosis and Inhibit Bone Nodule Formation In Vitro. Calcified Tissue International, 82, 191-201.

Murine Cardiac Tissue

Inagaki,K., Koyanagi,T., Berry,N.C., Sun,L. and Mochly-Rosen,D. (2008) Pharmacological Inhibition of ε-Protein Kinase C Attenuates Cardiac Fibrosis and Dysfunction in Hypertension-Induced Heart Failure. Hypertension, 51, 1565.

Human Periodontal Ligament Cell Line (HPL)

Inubushi,T., Tanaka,E., Rego,E.B., Kitagawa,M., Kawazoe,A., Ohta,A., Okada,H., Koolstra,J.H., Miyauchi,M. and Takata,T. (2008) Effects of Ultrasound on the proliferation and differentiation of Cementoblast lineage Cells. Journal of Periodontology, 79, 1-2.

Primary Hepatic Stellate Cells from Wild Type and Sept 4-/-Mice

Iwaisako,K., Hatano,E., Taura,K., Nakajima,A., Tada,M., Seo,S., Tamaki,N., Sato,F., Ikai,I. and Uemoto,S. (2008) Loss of Sept4 exacerbates liver fibrosis through the dysregulation of hepatic stellate cells. Journal of Hepatology, 49, 768-778.

Murine Lung Tissue

Kakizaki,T., Kohno,M., Watanabe,M., Tajima,A., Izumi,Y., Miyasho,T., Tasaka,S., Fukunaga,K., Maruyama,I. and Ishizaka,A. (2008) Exacerbation of Bleomycin-Induced Injury and Fibrosis by Pneumonectomy in the Residual Lung of Mice. Journal of Surgical Research, doi:10.1016/j.jss.2008.06.021.


Kang,Y.S., Ko,G.J., Lee,M.H., Song,H.K., Han,S.Y., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2008) Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfn448.

Murine Skin

Kanno,Y., Kaneiwa,A., Minamida,M., Kanno,M., Tomogane,K., Takeuchi,K., Okada,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2008) The Absence of uPAR Is Associated with the Progression of Dermal Fibrosis. Journal of Investigative Dermatology, doi:10.1038/jid.2008.157.

Human Gingival Fibroblasts

Kim,J.Y., Park,S.H., Cho,K.S., Kim,H.J., Lee,C.K., Park,K.K., Choi,S.H. and Chung,W.Y. (2008) Mechanism of Azithromycin Treatment on Gingival Overgrowth. Journal of Dental Research, 87, 1075.

Mouse Primary and NIH/3T3 Fibroblasts

Kitowska,K., Zakrzewicz,D., Königshoff,M., Chrobak,I., Grimminger,F., Seeger,W., Bulau,P. and Eickelberg,O. (2008) Functional role and species-specific contribution of arginases in pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L34-L45.


Ko,G.J., Kang,Y.S., Han,S.Y., Lee,M.H., Song,H.K., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2008) Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrology Dialysis Transplantation, 23, 2750-2760.

Lung Epithelial Cells

Königshoff,M., Balsara,N., Pfaff,E.M., Kramer,M., Chrobak,I., Seeger,W. and Eickelberg,O. (2008) Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis. PLoS ONE, 3 (5) e2142.doi:1371/journal.pone.0002142.

Rat Bone Marrow-Derived Mesenchymal Stromal Cells (BMSCs)

Kwon,D.S., Gao,X., Liu,Y.B., Dulchavsky,D.S., Danyluk,A.L., Bansal,M., Chopp,M., McIntosh,K., Arbab,A.S. and Dulchavsky,S.A. (2008) Treatment with bone marrow-derived stromal cells accelerates wound healing in diabetic rats. International Wound Journal, 5, 453-463.

Mouse Osteoblastic MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2008) Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-d-ribose induced dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells. European Journal of Pharmacology, 591, 1-6.

Murine Lung Tissue

Lee,K.S., Park,S.J., Kim,S.R., Min,K.H., Lee,K.Y., Choe,Y.H., Hong,S.H., Lee,Y.R., Kim,J.S. and Hong,S.J. (2008) Inhibition of VEGF blocks TGF-β1 production through a PI3K/Akt signalling pathway. European Respiratory Journal, 31, 523-531.

Murine Tissue

Lee,S.J., Van Dyke,M., Atala,A. and Yoo,J.J. (2008) Host Cell Mobilization for In Situ Tissue Regeneration. Rejuvenation Research, 11, 747-756.

Murine Lung Tissue

Le Saux,O., Teeters,K., Miyasato,S., Choi,J., Nakamatsu,G., Richardson,J.A., Starcher,B., Davis,E.C., Tam,E.K. and Jourdan-Le Saux,C. (2008) The role of caveolin-1 in pulmonary matrix remodeling and mechanical properties. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L1007-L1017.

Renal Tissue of Zucker Diabetic Fatty Rats

Li,Y., Qi,Y., Kim,M.S., Xu,K.Z., Huang,T.H., Rong,X., Murray,M. and Yamahara,J. (2008) Increased renal collagen cross-linking and lipid accumulation in nephropathy of Zucker diabetic fatty rats. Diabetes Metab Res Rev., 24, 498-506.

Cardiac Fibroblasts

Lijnen,P., Petrov,V., van Pelt,J. and Fagard,R. (2008) Inhibition of Superoxide Dismutase Induces Collagen Production in Cardiac Fibroblasts. American Journal of Hypertension, 21, 1129-1136.

Human Lung Tissue from Patients with Idiopathic Pulmonary Fibrosis and Human Fibroblasts

Lin,L., Zhou,Z., Zheng,L., Alber,S., Watkins,S., Ray,P., Kaminski,N., Zhang,Y. and Morse,D. (2008) Cross Talk between Id1 and Its Interactive Protein Dril1 Mediate Fibroblast Responses to Transforming Growth Factor-β in Pulmonary Fibrosis. American Journal of Pathology, 173, 337-346.

Rat Hepatic Stellate Cell Line (HSC-T6)

Lin,Y.L., Wu,C.F. and Huang,Y.T. (2008) Effects of rhubarb on migration of rat hepatic stellate cells. Journal of Gastroenterology and Hepatology, doi:10.1111/j.1440-1746.2008.05573.x.

Osteoblasts

Liu,H., Yazici,H., Ergun,C., Webster,T.J. and Bermek,H. (2008) An in vitro evaluation of the Ca/P ratio for the cytocompatibility of nano-to-micron particulate calcium phosphates for bone regeneration. Acta Biomaterialia, 4, 1472-1479.

Normal Human Bronchial Epithelial Cells

Malavia,N.K., Mih,J.D., Raub,C.B., Dinh,B.T., George,S.C., Tirumurugaan,K.G., Kang,B.N., Panettieri,R.A., Foster,D.N. and Walseth,T.F. (2008) IL-13 induces a bronchial epithelial phenotype that is profibrotic. Respiratory Research, 9, 27.

Leiomyoma and Myometrial Cells

Malik,M., Webb,J. and Catherino,W.H. (2008) Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells. Clinical Endocrinology, 69, 462-470.

Rat Cardiomyocytes

Mancuso,P., Rahman,A., Hershey,S.D., Dandu,L., Nibbelink,K.A. and Simpson,R.U. (2008) 1, 25-Dihydroxyvitamin-D3 Treatment Reduces Cardiac Hypertrophy and Left Ventricular Diameter in Spontaneously Hypertensive Heart Failure-prone (cp/+) Rats Independent of Changes in Serum Leptin. Journal of Cardiovascular Pharmacology, 51, 559-564.

Murine Model of Plexiform Neurofibroma

McDaniel,A.S. (2008) The role of PAK1 in the cellular and molecular components of plexiform neurofibromas.

http://hdl.handle.net/1805/1696

Human Lung Fibroblasts and Myofibroblasts

Milam,J.E., Keshamouni,V.G., Phan,S.H., Hu,B., Gangireddy,S.R., Hogaboam,C.M., Standiford,T.J., Thannickal,V.J. and Reddy,R.C. (2008) PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L891-L901.

Human Retinal Pigment Epithelial (ARPE-19) Cell Line

Morales,S.A., Mareninov,S., Wadehra,M., Zhang,L., Goodglick,L., Braun,J. and Gordon,L.K. (2008) Epithelial Membrane Protein 2 (EMP2) Controls Collagen Gel Contraction in ARPE-19 Cells by Modulating FAK Activation. Investigative Ophthalmology & Visual Science, doi:10:1167/iovs.07-1598.

Murine Lung Tissue

Mozaffarian,A., Brewer,A.W., Trueblood,E.S., Luzina,I.G., Todd,N.W., Atamas,S.P. and Arnett,H.A. (2008) Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis. The Journal of Immunology, 181, 7243.

http://hdl.handle.net/1805/1696

Human IPF/UIP Fibroblasts

Murray,L.A., Argentieri,R.L., Farrell,F.X., Bracht,M., Sheng,H., Whitaker,B., Beck,H., Tsui,P., Cochlin,K. and Evanoff,H.L. (2008) Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2. International Journal of Biochemistry and Cell Biology, 40, 2174-2182.


Murray,L.A., Hackett,T.L., Warner,S.M., Shaheen,F., Argentieri,R.L., Dudas,P., Farrell,F.X. and Knight,D.A. (2008) BMP-7 Does Not Protect against Bleomycin-Induced Lung or Skin Fibrosis. PLoS ONE, 3,e4039.

Bovine Articular Cartilage

Natoli,R.M., Scott,C.C. and Athanasiou,K.A. (2008) Temporal Effects of Impact on Articular Cartilage Cell Death, Gene Expression, Matrix Biochemistry, and Biomechanics. Annals of Biomedical Engineering, 36, 780-792.

Murine Model of Liver Cirrhosis

Nishibe,Y., Kaneko,H., Suzuki,H., Abe,T., Matsuura,Y. and Takaku,H. (2008) Baculovirus-mediated interferon alleviates dimethylnitrosamine-induced liver cirrhosis symptoms in a murine model. Gene Therapy, 15, 990-997.

Horse Superficial Digital Flexor Tendon

Nixon,A.J., Dahlgren,L.A., Haupt,J.L., Yeager,A.E. and Ward,D.L. (2008) Effect of adipose-derived nucleated cell fractions on tendon repair in horses with collagenase-induced tendinitis. American Journal of Veterinary Research, 69, 928-937.

Rat Mesenchymal Stem Cells

Ocarino,N.M., Boeloni,J.N., Goes,A.M., Silva,J.F., Marubayashi,U. and Serakides,R. (2008) Osteogenic differentiation of mesenchymal stem cells from osteopenic rats subjected to physical activity with and without nitric oxide synthase inhibition. Nitric Oxide, 19,320-325.

Murine Intestinal Tissue

Okoshi,K., Kubo,H., Nagayama,S., Tabata,C., Kadokawa,Y., Hisamori,S., Yonenaga,Y., Fujimoto,A., Mori,A. and Onodera,H. (2008) All-trans-Retinoic Acid Attenuates Radiation-Induced Intestinal Fibrosis in Mice. Journal of Surgical Research, 150, 53-59.

Normal Human Lung Fibroblast (NHLF) Cells

Pandey, A., Scarborough, R. M., and Venkatraman, M. S. (2008) Compositions and methods for inhibiting TGF-β. US Patent 7314939.


Park,H.J., Cho,D.H., Kim,H.J., Lee,J.Y., Cho,B.K., Bang,S.I., Song,S.Y., Yamasaki,K., Di Nardo,A. and Gallo,R.L. (2008) Collagen Synthesis Is Suppressed in Dermal Fibroblasts by the Human Antimicrobial Peptide LL-37. Journal of Investigative Dermatology, doi:10.1038/jid.2008.320.

Rabbit Mesenchymal Cells

Park,K.H. and Na,K. (2008) Effect of growth factors on chondrogenic differentiation of rabbit mesenchymal cells embedded in injectable hydrogels. Journal of Bioscience and Bioengineering, 106, 74-79.

Human Mesenchymal Stem Cells

Richardson,S.M., Hughes,N., Hunt,J.A., Freemont,A.J. and Hoyland,J.A. (2008) Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels. Biomaterials, 29, 85-93.

Normal Human Lung Fibroblast (NHLF) Cells

Scarborough, R. M., Pandey, A., and Mehrotra, M. (2008) Compositions and method for inhibiting TGF-β. US Patent 7361669.

Lacrimal Gland Extra Cellular Matrix from Healthy (BALB/C) and Diseased (NOD) Mice

Schenke-Layland,K., Xie,J., Angelis,E., Starcher,B., Wu,K., Riemann,I., MacLellan,W.R. and Hamm-Alvarez,S.F. (2008) Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren's syndrome. Matrix Biology, 27, 53-66.

Human Anterior Cruciate Ligament Cell and T-Lymphocyte Cultures

Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S. and Park,J.K. (2008) Increase in cell migration and angiogenesis in a composite silk scaffold for tissue-engineered ligaments. Journal of Orthopaedic Research: doi:1002/jor.20752.

Mouse Model of Dermal Fibrosis

Shibusawa,Y., Negishi,I., Tabata,Y. and Ishikawa,O. (2008) Mouse model of dermal fibrosis induced by one-time injection of bleomycin-poly (L-lactic acid) microspheres. Rheumatology, 47, 454-457.

Several Tumor Cell Lines

Shimazaki,M. and Kudo,A. (2008) Impaired capsule formation of tumors in periostin-null mice. Biochemical and Biophysical Research Communications, 367, 736-742.

Murine Lung Tissue

Shofer,S., Badea,C., Qi,Y., Potts,E., Foster,W.M. and Johnson,G.A. (2008) A micro-CT analysis of murine lung recruitment in bleomycin-induced lung injury. Journal of Applied Physiology, 105, 669-677.

Murine Lung Tissue

Shvedova,A.A., Kisin,E., Murray,A.R., Johnson,V.J., Gorelik,O., Arepalli,S., Hubbs,A.F., Mercer,R.R., Keohavong,P. and Sussman,N. (2008) Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L552-L565.

Human Fibroblast Cultures from Healthy Patients and Patients with Systemic Sclerosis (SSC)

Skhirtladze,C., Distler,O., Dees,C., Akhmetshina,A., Busch,N., Venalis,P., Zwerina,J., Spriewald,B., Pileckyte,M. and Schett,G. (2008) Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis. Arthritis and Rheumatism, 58, 1475-1484.

Cultured Mesangial Cells

Song,H.K., Lee,M.H., Kim,B.K., Park,Y.G., Ko,G.J., Kang,Y.S., Han,J.Y., Han,S.Y., Han,K.H. and Kim,H.K. (2008) Visfatin: A New Player in Mesangial Cell Physiology and Diabetic Nephropathy. American Journal of Physiology- Renal Physiology, doi:10:1152/ajprenal.90231.2008.

Osteoblasts

Souza,D.M., Andrade,A.L., Fabris,J.D., Valério,P., Góes,A.M., Leite,M.F. and Domingues,R.Z. (2008) Synthesis and in vitro evaluation of toxicity of silica-coated magnetite nanoparticles. Journal of Non-Crystalline Solids, 354, 4894-4897.

Primary Cultures of Dermal Papilla Cells, Dermal Sheath Cells and Interfollicular Dermal Fibroblasts from Female Temporo-Occipital Scalp

Stevenson,S., Taylor,A.H., Meskiri,A., Sharpe,D.T. and Thornton,M.J. (2008) Differing responses of human follicular and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial growth factor secretion. Wound Repair and Regeneration, 16, 243-253.

Dermis Extracellular Matrix

Sun,W.Q. and Leung,P. (2008) Calorimetric study of extracellular tissue matrix degradation and instability after gamma irradiation. Acta Biomaterialia, 4, 817-826.

Rat Pancreatic Stellate Cells and Rat Pancreatic Acinar Cells

Tahara,J., Shimizu,K. and Shiratori,K. (2008) Engulfment of Necrotic Acinar Cells by Pancreatic Stellate Cells Inhibits Pancreatic Fibrogenesis. Pancreas, 37, 69-74.

Murine Lung Tissue

Tourdot,S., Mathie,S., Hussell,T., Edwards,L., Wang,H., Openshaw,P.J.M., Schwarze,J. and Lloyd,C.M. (2008) Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior allergen sensitization. Clinical & Experimental Allergy, 38, 1016-1024.

Murine Cardiac Tissue from Transgenic Mice

Ueno,M., Suzuki,J., Zenimaru,Y., Takahashi,S., Koizumi,T., Noriki,S., Yamaguchi,O., Otsu,K., Shen,W.J. and Kraemer,F.B. (2008) Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice. American Journal of Physiology- Endocrinology and Metabolism, 294, E1109-E1118.

Murine Lung Tissue

Walters, D.M. and Kleeberger, S.R. (2008) Mouse Models of Bleomycin-Induced Pulmonary Fibrosis. Current Protocols in Pharmacology, doi: 10.1002/0471141755.ph0546s40.

Murine Lung Tissue

Wang,C., Abe,S., Matsuda,K., Yu,C., Li,Y., Usuki,J., Azuma,A. and Kudoh,S. (2008) Effects of Gefitinib on Radiation-induced Lung Injury in Mice. Journal of Nippon Medical School, 75, 96-105.

Human Primary Lung Fibroblasts and Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis

Xia,H., Diebold,D., Nho,R., Perlman,D., Kleidon,J., Kahm,J., Avdulov,S., Peterson,M., Nerva,J. and Bitterman,P. (2008) Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis. Journal of Experimental Medicine, doi:10.1084/jem.20080001.

Murine Lung Tissue

Yamauchi,E., Shoji,S., Nishihara,M., Shimoda,T. and Nishima,S. (2008) Contribution of Lung Fibroblast Migration in the Fibrotic Process of Airway Remodelling in Asthma. Allergology International, 57, 73-78.

Canine Chondrocytes

Yanez,J.A., Remsberg,C.M., Vega-Villa,K.R., Miranda,N.D., Navas,J., Ohgami,Y., McCormick,D., Hughes,K., Temple,C. and Martinez,S.A. (2008) Pharmacological Evaluation of Glyco-Flex® III and its Constituents on Canine Chondrocytes. Journal of Medical Sciences, 8, 98-101.

Murine Lung Tissue

Zheng,T., Liu,W., Oh,S.Y., Zhu,Z., Hu,B., Homer,R.J., Cohn,L., Grusby,M.J. and Elias,J.A. (2008) IL-13 Receptor α2 Selectively Inhibits IL-13-Induced Responses in the Murine Lung. The Journal of Immunology, 180, 522-529.

Skin

Zheng,T., Oh,M.H., Oh,S.Y., Schroeder,J.T., Glick,A.B. and Zhu,Z. (2008) Transgenic Expression of Interleukin-13 in the Skin Induces a Pruritic Dermatitis and Skin Remodeling. Journal of Investigative Dermatology, doi:10.1038/jid.2008.295.

2007 Dermal Fibroblasts Ahlfors,J.E.W. and Billiar,K.L. (2007) Biomechanical and biochemical characteristics of a human fibroblast-produced

and remodeled matrix. Biomaterials, 28, 2183-2191.

Murine Vascular and Pulmonary Cells

Ambalavanan,N., LI,P., Bulger,A., Murphy-Ullrich,J., Oparil,S. and Chen,Y.F. (2007) Endothelin-1 Mediates Hypoxia-Induced Increases in Vascular Collagen in the Newborn Mouse Lung. Pediatr Res, 61, 559-564.

Human Uterine Leiomyomas

Britten,J.L., Malik,M., Payson,M., Norian,J., Joseph,D. and Catherino,W.H. (2007) All-trans retinoic acid regulates collagen synthesis in human uterine leiomyomas. Fertility and Sterility, 88, 218.

Equine Tendon-Derived Fibrillar Collagen Constructs

Butler,L.M., Metson-Scott,T., Felix,J., Abhyankar,A., Rainger,G.E., Farndale,R.W., Watson,S.P. and Nash,G.B. (2007) Sequential adhesion of platelets and leukocytes from flowing whole blood onto a collagen-coated surface: Requirement for a GpVI-binding site in collagen. Thromb Haemost, 97, 814-821.

Rat Lung Tissue

Chen,C.M., Wang,L.F., Chou,H.C., Lang,Y.D. and Lai,Y.P. (2007) Up-regulation of Connective Tissue Growth Factor in Hyperoxia-Induced Lung Fibrosis. Pediatric Research, 62, 128 – 133.

Murine Osteoblastic MC3T3-E1 Cell Line

Choi,E.M. (2007) Modulatory effects of luteolin on osteoblastic function and inflammatory mediators in osteoblastic MC3T3-E1 cells. Cell Biology International, 31, 870-877.


Choi,E.M. (2007) Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-α-induced production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells. Pharmazie, 62, 216-220.

Human Mesenchymal Stem Cells

Choi,K.M., Yoon,H.H., Seo,Y.K., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S., Kim,Y.J. and Park,J.K. (2007) Effect of essential and nonessential amino acid compositions on the in vitro behavior of human mesenchymal stem cells. Korean Journal of Chemical Engineering, 24, 1058-1063.

Murine Cardiac Fibroblasts

Colston,J.T., de la Rosa,S.D., Koehler,M., Gonzales,K., Mestril,R., Freeman,G.L., Bailey,S.R. and Chandrasekar,B. (2007) Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. American Journal of Physiology- Heart and Circulatory Physiology, 293, H1839.

Rat Hepatic Stellate Cells

Comporti,M., Signorini,C., Arezzini,B., Vecchio,D., Monaco,B. and Gardi,C. (2007) F2-isoprostanes are not just markers

of oxidative stress. Free Radical Biology and Medicine, 44, 247-256.

Mouse Lung Tissue

Denis,O., van den Brûle,S., Heymans,J., Havaux,X., Rochard,C., Huaux,F. and Huygen,K. (2007) Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling. Immunology, 122, 268-278.

Human Colonic Myofibroblasts

Di Sabatino,A., Pender,S.L.F., Jackson,C.L., Prothero,J.D., Gordon,J.N., Picariello,L., Rovedatti,L., Docena,G., Monteleone,G. and Rampton,D.S. (2007) Functional Modulation of Crohn’s Disease Myofibroblasts by Anti-Tumor Necrosis Factor Antibodies. Gastroenterology, 133, 137-149.


Digel,I., Kurulgan,E., Linder,P., Kayser,P., Porst,D., Braem,G.J., Zerlin,K., Artmann,G.M. and Artmann,A.T. (2007) Decrease in extracellular collagen crosslinking after NMR magnetic field application in skin fibroblasts. Medical and Biological Engineering and Computing, 45, 91-97.

Murine Muscle Samples

DuBay,D.A., Choi,W., Urbanchek,M.G., Wang,X., Adamson,B., Dennis,R.G., Kuzon Jr,W.M. and Franz,M.G. (2007) Incisional Herniation Induces Decreased Abdominal Wall Compliance via Oblique Muscle Atrophy and Fibrosis. Ann Surg, 245, 140-146.

Murine Kidney Samples

El Chaar,M., Chen,J., Seshan,S.V., Jha,S., Richardson,I., Ledbetter,S.R., Vaughan Jr,E.D., Poppas,D.P. and Felsen,D. (2007) Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction. American Journal of Physiology- Renal Physiology, 292, F1291-F1301.

Murine Lung Tissue

Faress,J.A., Nethery,D.E., Kern,E.F.O., Eisenberg,R., Jacono,F.J., Allen,C.L. and Kern,J.A. (2007) Bleomycin Induced Pulmonary Fibrosis is Attenuated by a Monoclonal Antibody Targeting HER2. Journal of Applied Physiology, 103, 2077-2083.

Murine Colon Samples

Fichtner-Feigl,S., Fuss,I.J., Young,C.A., Watanabe,T., Geissler,E.K., Schlitt,H.J., Kitani,A. and Strober,W. (2007) Induction of IL-13 Triggers TGF-beta1-Dependent Tissue Fibrosis in Chronic 2, 4, 6-Trinitrobenzene Sulfonic Acid Colitis. The Journal of Immunology, 178, 5859.

Leporine Mesenchymal Stem Cells

Hannouche,D., Terai,H., Fuchs,J.R., Terada,S., Zand,S., Nasseri,B.A., Petite,H., Sedel,L. and Vacanti,J.P. (2007) Engineering of implantable cartilaginous structures from bone marrow-derived mesenchymal stem cells. Tissue Eng. 13, 87-99.

Human Embryonic Stem Cells (hESCs) – Cell Lines H9 and BG01V

Hoben,G.M., Koay,E.J. and Athanasiou,K.A. (2007) Fibrochondrogenesis in Two Embryonic Stem Cell Lines: Effects of Differentiation Timelines. Stem Cells, 26, 422- 430.

Murine Liver Tissues

Hsu,Y.C., Chiu,Y.T., Cheng,C.C., Wu,C.F., Lin,Y.L. and Huang,Y.T. (2007) Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis. Journal of Gastroenterology and Hepatology, 22, 99-111.

Human Primary Keloid Fibroblast Culture Supernatant

Hsu,Y.C., Hsiao,M., Chien,Y.W. and Lee,W.R. (2007) Exogenous nitric oxide stimulated collagen type I expression and TGF-β1 production in keloid fibroblasts by a cGMP-dependent manner. Nitric Oxide, 16, 258-265.

Murine Pulmonary Lysates, Macrophage Cell Line RAW 264.7 and Human Normal Lung Fibroblast MRC-5 Cell Line

Hsu,Y.C., Wang,L.F. and Chien,Y.W. (2007) Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis. Free Radical Biology and Medicine, 42, 599-607.

Human Primary Fibroblast Culture and Murine Dermal Tissue Samples

Huber,L.C., Distler,J.H., Moritz,F., Hemmatazad,H., Hauser,T., Michel,B.A., Gay,R.E., Matucci-Cerinic,M., Gay,S. and Distler,O. (2007) Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. Arthritis Rheum, 56, 2755-2764.

Murine Bladder Tissue

Imamura,M., Kanematsu,A., Yamamoto,S., Kimura,Y., Kanatani,I., Ito,N., Tabata,Y. and Ogawa,O. (2007) Basic fibroblast growth factor modulates proliferation and collagen expression in urinary bladder smooth muscle cells. American Journal of Physiology- Renal Physiology, 293, F1007-F1017.

Dog Cardiovascular Tissue

Jugdutt,B.I., Idikio,H. and Uwiera,R.R.E. (2007) Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction. Molecular and Cellular Biochemistry, 303, 27-38.

Murine Lung Tissue

Kai,Y., Yoneyama,H., Koyama,J., Hamada,K., Kimura,H. and Matsushima,K. (2007) Treatment with chondroitinase ABC alleviates bleomycin-induced pulmonary fibrosis. Medical Molecular Morphology, 40, 128-140.

Murine Pancreatic Stellate Cells

Kaku,T., Oono,T., Zhao,H., Gibo,J., Kawabe,K., Ito,T. and Takayanagi,R. (2007) IS-741 Attenuates Local Migration of Monocytes and Subsequent Pancreatic Fibrosis in Experimental Chronic Pancreatitis Induced by Dibutyltin Dichloride in Rats. Pancreas, 34, 299-309.

Murine Lung Homogenates

Kang,H.R., Lee,C.G., Homer,R.J. and Elias,J.A. (2007) Semaphorin 7A plays a critical role in TGF-β1-induced pulmonary fibrosis. J. Exp. Med., 204, 1083.

Murine Lung Tissue

Kang,H.R., Cho,S.J., Lee,C.G., Homer,R.J. and Elias,J.A. (2007) TGF-beta 1 stimulates pulmonary fibrosis and inflammation via a bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. Journal of Biological Chemistry, 282, 7723-7732.

Murine Lung Tissue

Kanno,Y., Kuroki,A., Okada,K., Tomogane,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2007) α2-Antiplasmin is involved in the production of transforming growth factor β1 and fibrosis. Journal of Thrombosis and Haemostasis, 5, 2266-2273.

Human Stem Cells

Kim,S.G., Jeon,C.H., Suh,H., Choe,J.Y. and Shin,I.H. (2007) P-glycoprotein expression in extracellular matrix formation of chondrogenic differentiation of human adult stem cells. Cell Biology International, 31, 1042-1048.

Human Myocardial Samples

Klotz,S., Danser,A.H., Foronjy,R.F., Oz,M.C., Wang,J., Mancini,D., D'Armiento,J. and Burkhoff,D. (2007) The Impact of Angiotensin-Converting Enzyme Inhibitor Therapy on the Extracellular Collagen Matrix During Left Ventricular Assist Device Support in Patients With End-Stage Heart Failure. Journal of the American College of Cardiology, 49, 1166.

Murine Lung Tissue

Kohan, M., Bader,R., Puxeddu,I., Levi-Schaffer,F., Breuer,R. and Berkman,N. (2007) Enhanced osteopontin expression in a murine model of allergen-induced airway remodelling. Clinical & Experimental Allergy, 37, 1444-1454.

Ovine Mesenchymal Progenitor Cells

Kunisaki,S.M., Fuchs,J.R., Steigman,S.A. and Fauza,D.O. (2007) A comparative analysis of cartilage engineered from different perinatal mesenchymal progenitor cells. Tissue Eng. 13, 2633 – 2644.

Human Fibroblast Cell Lines

Lareu,R.R., Arsianti,I., Subramhanya,H.K., Yanxian,P., Raghunath,M. (2007) In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engineering; a preliminary study. Tissue Eng. 13, 385-391.

Murine Cementoblastic Cell Line, OCCM-30

La-Bona,D.A., Tanaka,E., Inubushi,T., Oka,H., Ohta,A., Okada,H., Miyauchi,M., Takata,T. and Tanne,K. (2007) Cementoblast response to low-and high-intensity ultrasound. Archives of Oral Biology, 53, 318-323.

Ovine Bone Marrow Mesenchymal Cells

Luo,Z.J. and Seedhom,B.B. (2007) Light and low-frequency pulsatile hydrostatic pressure enhances extracellular matrix formation by bone marrow mesenchymal cells: an in-vitro study with special reference to cartilage repair. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 221, 499-507.

Murine Lung Tissue

Maret,M., Ruffie,C., Periquet,B., Campo,A.M., Menevret,M., Phelep,A., Dziewiszek,K., Druilhe,A. and Pretolani,M. (2007) Liposomal Retinoic Acids Modulate Asthma Manifestations in Mice. Journal of Nutrition, 137, 2730 – 2736.

Murine Dermal Biopsies

Matsushita,T., Fujimoto,M., Hasegawa,M., Matsushita,Y., Komura,K., Ogawa,F., Watanabe,R., Takehara,K. and Sato,S. (2007) BAFF Antagonist Attenuates the Development of Skin Fibrosis in Tight-Skin Mice. Journal of Investigative Dermatology, 127, 2772-2780.

Murine Lung Tissue

Mishra,A., Wang,M., Schlotman,J., Nikolaidis,N.M., DeBrosse,C.W., Karow,M.L. and Rothenberg,M.E. (2007) Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. American Journal of Physiology- Lung Cellular and Molecular Physiology, 293, L305.


Misson,P., Brombacher,F., Delos,M., Lison,D. and Huaux,F. (2007) Type 2 immune response associated with silicosis is not instrumental in the development of the disease. American Journal of Physiology- Lung Cellular and Molecular Physiology, 292, L107-L113.

Murine Bronchoalveolar Lavage Fluid

Morschl,E., Volmer,J.B., Molina,J.G., Lee,J.J., Ochkur,S.I. and Blackburn,M.R. (2007) A3 Adenosine Receptors Modulate Eosinophil Function In Bleomycin-Induced Lung Injury. The Journal of Allergy and Clinical Immunology, 119, 218.

Murine Fibroblast NIH3T3 Cell Line

Nishi,Y., Sano,H., Kawashima,T., Okada,T., Kuroda,T., Kikkawa,K., Kawashima,S., Tanabe,M., Goto,T. and Matsuzawa,Y. (2007) Role of Galectin-3 in Human Pulmonary Fibrosis. Allergology International, 1, 57-65.

Murine Lung Tissue

Niu,N., Le Goff,M.K., Li,F., Rahman,M., Homer,R.J. and Cohn,L. (2007) A Novel Pathway That Regulates Inflammatory Disease in the Respiratory Tract. The Journal of Immunology, 178, 3846.


Nomiyama,Y., Tashiro,M., Yamaguchi,T., Watanabe,S., Taguchi,M., Asaumi,H., Nakamura,H. and Otsuki,M. (2007) High Glucose Activates Rat Pancreatic Stellate Cells Through Protein Kinase C and p38 Mitogen-Activated Protein Kinase Pathway. Pancreas, 34, 364-372.

Human Epithelial Cells

Ornatowski,W., Poschet,J.F., Perkett,E., Taylor-Cousar,J.L. and Deretic,V. (2007) Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A induced cytotoxicity. Journal of Clinical Investigation, 117, 3489.

Murine Primary Osteoblasts

Orriss,I.R., Utting,J.C., Brandao-Burch,A., Colston,K., Grubb,B.R., Burnstock,G. and Arnett,T.R. (2007) Extracellular Nucleotides Block Bone Mineralization in Vitro: Evidence for Dual Inhibitory Mechanisms Involving Both P2Y2 Receptors and Pyrophosphate. Endocrinology, 148, 4208.

Murine Pulmonary Tissue

Pena,A.M., Fabre,A., Débarre,D., Marchal-Somme,J., Crestani,B., Martin,J.L., Beaurepaire,E. and Schanne-Klein,M.C. (2007) Three-dimensional investigation and scoring of extracellular matrix remodeling during lung fibrosis using multiphoton microscopy. Microsc.Res.Tech. 70, 162 – 170.

Murine Lung Tissue

Pilling,D., Roife,D., Wang,M., Ronkainen,S.D., Crawford,J.R., Travis,E.L. and Gomer,R.H. (2007) Reduction of Bleomycin-Induced Pulmonary Fibrosis by Serum Amyloid P. The Journal of Immunology, 179, 4035.

Human Primary Fetal and Postnatal Dermal Fibroblasts

Rolfe,K., Grobbelaar,A.O. and Linge,C. (2007) Is TGF-B1 signalling active in fetuses? Journal of Plastic, Reconstructive & Aesthetic Surgery, 60, S11.

Human Fetal and Postnatal Fibroblasts

Rolfe,K.J., Richardson,J., Vigor,C., Irvine,L.M., Grobbelaar,A.O. and Linge,C. (2007) A Role for TGF-bold italic beta 1-Induced Cellular Responses during Wound Healing of the Non-Scarring Early Human Fetus? Journal of Investigative Dermatology, 127, 2656-2667.

Ovine Blood-Derived Endothelial Progenitor Cells

Sales,V.L., Engelmayr Jr,G.C., Johnson Jr,J.A., Gao,J., Wang,Y., Sacks,M.S. and Mayer Jr,J.E. (2007) Protein Precoating of Elastomeric Tissue-Engineering Scaffolds Increased Cellularity, Enhanced Extracellular Matrix Protein Production, and Differentially Regulated the Phenotypes of Circulating Endothelial Progenitor Cells. Circulation, 116, 155-163.

Rat Choloangiocytes

Sato,Y., Harada,K., Ozaki,S., Furubo,S., Kizawa,K., Sanzen,T., Yasoshima,M., Ikeda,H., Sasaki,M. and Nakanuma,Y. (2007) Cholangiocytes with Mesenchymal Features Contribute to Progressive Hepatic Fibrosis of the Polycystic Kidney Rat. American Journal of Pathology, 171, 1859 – 1871.

Equine Flexor Digitorum Superficialis Tendon (SDFT) Explants

Schnabel,L.V., Mohammed,H.O., Miller,B.J., McDermott,W.G., Jacobson,M.S., Santangelo,K.S. and Fortier,L.A. (2007) Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons. J Orthop Res, 25, 230-240.

Murine Lung Tissue

Shvedova,A.A., Kisin,E.R., Murray,A.R., Gorelik,O., Arepalli,S., Castranova,V., Young,S.H., Gao,F., Tyurina,Y.Y., Oury,T.D. and Kagan,V.E. (2007) Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice. Toxicology and Applied Pharmacology, 221, 339-348.

Murine Lung Homogenate

Swain,S.D., Han,S., Harmsen,A., Shampeny,K. and Harmsen,A.G. (2007) Pulmonary Hypertension Can Be a Sequela of Prior Pneumocystis Pneumonia. American Journal of Pathology, 171, 790-799.

Murine Sponge Implants

Tkalcević,V.I., Cuzić,S., Brajsa,K., Mildner,B., Bokulić,A., Situm,K., Perović,D., Glojnarić,I. and Parnham,M.J. (2007) Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expression. European Journal of Pharmacology, 570, 212-221.


Vittal,R., Zhang,H., Han,M.L.K., Moore,B.B., Horowitz,J.C. and Thannickal,V.J. (2007) Effects of the Protein Kinase Inhibitor, Imatinib Mesylate, on Epithelial/Mesenchymal Phenotypes: Implications for Treatment of Fibrotic Diseases. Journal of Pharmacology and Experimental Therapeutics, 321, 35-44.

Murine Lung Tissue

Wallach-Dayan,S.B., Golan-Gerstl,R. and Breuer,R. (2007) Evasion of myofibroblasts from immune surveillance: A mechanism for tissue fibrosis. Proceedings of the National Academy of Sciences, 104, 20460.

Leporine Chondrocyte

Xie,J.U.N., Han,Z., Kim,S.O.O.H., Kim,Y.H.A. and Takehisa Matsuda,P.D. (2007) Mechanical Loading-Dependence of mRNA Expressions of Extracellular Matrices of Chondrocytes Inoculated into Elastomeric Microporous Poly (L-lactide-co-e-caprolactone) Scaffold. Tissue Engineering, 13, 29-40.

Bovine Decellularised Vocal Fold Lamina and Human Vocal Fold Fibroblast Primary Culture

Xu,C.C., Chan,R.W. and Tirunagari,N. (2007) A Biodegradable, Acellular Xenogeneic Scaffold for Regeneration of the Vocal Fold Lamina Propria. Tissue Engineering, 13, 551-566.

Murine Dermal Biopsy

Yamamoto,T., Yokozeki,H. and Nishioka,K. (2007) Fas-and FasL-deficient mice are resistant to the induction of bleomycin-induced scleroderma. Archives of Dermatological Research, 298, 465-468.

Murine Dermal Tissue

Yoshioka,T., Imura,K., Hikita,I., Hirasawa,T., Sakata,T., Matsutani,T., Horikawa,T. and Arimura,A. (2007) Impact of T-cell receptor V haplotypes on the development of dermatitis in DS-Nh mice: synergistic production of interleukin-13 caused by staphylococcal enterotoxin C and peptide glycans from Staphylococcus aureus. Immunology, 121, 51-61.

2006

Murine Pacreatic Stellate Cells

Asaumi,H., Watanabe,S., Taguchi,M., Tashiro,M., Nagashio,Y., Nomiyama,Y., Nakamura,H. and Otsuki,M. (2006) Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits ethanol-induced activation of pancreatic stellate cells. European Journal of Clinical Investigation, 36, 113-122.

Leporine cartilage and Chondrocyte Explants

Baek,Y.H., Huh,J.E., Lee,J.D., Choi,D.Y. and Park,D.S. (2006) Effect of Aralia cordata Extracts on Cartilage Protection and Apoptosis Inhibition. Biological & Pharmaceutical Bulletin, 29, 1423-1430.

Porcine Aortic Valves

Balachandran,K., Konduri,S., Sucosky,P., Jo,H. and Yoganathan,A.P. (2006) An Ex Vivo Study of the Biological Properties of Porcine Aortic Valves in Response to Circumferential Cyclic Stretch. Annals of Biomedical Engineering, 34, 1655-1665.

Human Articular Chondrocytes

Banu,N., Tsuchiya,T. and Sawada,R. (2006) Effects of a biodegradable polymer synthesized with inorganic tin on the chondrogenesis of human articular chondrocytes. J Biomed Mater Res A. 77, 84-89.

Murine Collagen Deposition on Polypropylene Tapes

Bogusiewicz,M., Wrobel,A., Jankiewicz,K., Adamiak,A., Skorupski,P., Tomaszewski,J. and Rechberger,T. (2006) Collagen deposition around polypropylene tapes implanted in the rectus fascia of female rats. European Journal of Obstetrics & Gynecology and Reproductive Biology, 124, 106-109.

Human Ventricular Tissue Samples

Bruggink,A.H., van Oosterhout,M.F.M., de Jonge,N., Ivangh,B., van Kuik,J., Voorbij,R.H.A.M., Cleutjens,J.P.M., Gmelig-Meyling,F.H.J. and de Weger,R.A. (2006) Reverse Remodeling of the Myocardial Extracellular Matrix After Prolonged Left Ventricular Assist Device Support Follows a Biphasic Pattern. Journal of Heart and Lung Transplantation, 25, 1091-1098.


Chan,E.S.L., Fernandez,P., Merchant,A.A., Montesinos,M.C., Trzaska,S., Desai,A., Tung,C.F., Khoa,D.N., Pillinger,M.H. and Reiss,A.B. (2006) Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma. Arthritis & Rheumatism, 54, 2632-2642.

Murine Lung Samples

Cho,S.J., Kang,M.J., Homer,R.J., Kang,H.R., Zhang,X., Lee,P.J., Elias,J.A. and Lee,C.G. (2006) Role of Early Growth Response-1 (Egr-1) in Interleukin-13-induced Inflammation and Remodeling. Journal of Biological Chemistry, 281, 8161.

Leporine Articular Cartilage

Cho,Y.J., Huh,J.E., Kim,D.Y., Kim,N.J., Lee,J.D., Baek,Y.H., Cho,E.M., Yang,H.R., Choi,D.Y. and Park,D.S. (2006) Effect of Betula platyphylla var. japonica on Proteoglycan Release, Type II Collagen Degradation, and Matrix Metalloproteinase Expression in Rabbit Articular Cartilage Explants. Biological & Pharmaceutical Bulletin, 29, 1408-1413.

Murine Hepatic Stellate Cells HSC-T6 and Liver Samples

Chong,L.W., Hsu,Y.C., Chiu,Y.T., Yang,K.C. and Huang,Y.T. (2006) Anti-Fibrotic Effects of Thalidomide on Hepatic Stellate Cells and Dimethylnitrosamine-Intoxicated Rats. Journal of Biomedical Science, 13, 403-418.

Murine Liver Tissue

Chou,W-Y., Lu,C-n., Lee,T-h., Wu,C-l., Hung,K-s., Concejero,A.M., Jawan,B. and Wang,C-h. (2006) Electroporative interleukin-10 gene transfer ameliorates carbon tetrachlo-ride-induced murine liver fibrosis by MMP and TIMP modulation. Acta Pharmacologica Sinica 27, 469-476.

Murine Bronchial Lavages

Chunn,J.L., Mohsenin,A., Young,H.W.J., Lee,C.G., Elias,J.A., Kellems,R.E. and Blackburn,M.R. (2006) Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. American Journal of Physiology- Lung Cellular and Molecular Physiology, 290, 579-587.


Distler,J.H., Jüngel,A., Caretto,D., Schulze-Horsel,U., Kowal-Bielecka,O., Gay,R.E., Michel,B.A., Müller-Ladner,U., Kalden,J.R., Gay,S. and Distler,O. (2006) Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells. Arthritis Rheum, 54, 214-225.


Distler,J.H., Jüngel,A., Huber,L.C., Schulze-Horsel,U., Zwerina,J., Gay,R.E., Michel,B.A., Hauser,T., Schett,G. and Gay,S. (2006) Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum, 56, 311-322.

Murine Abdominal Wall Samples

DuBay,D.A., Wang,X., Adamson,B., Kuzon,W.M., Dennis,R.G. and Franz,M.G. (2006) Mesh incisional herniorrhaphy increases abdominal wall elastic properties: A mechanism for decreased hernia recurrences in comparison with suture repair. Surgery, 140, 14-24.

Human Normal and Keloid Fibroblasts

Duong,H.S., Zhang,Q.Z., Le,A.D., Kelly,A.P., Kamdar,R. and Messadi,D.V. (2006) Elevated prolidase activity in keloids: correlation with type I collagen turnover. Br J Dermatol 154, 820-828.

Ovine Bone Marrow-Derived Mesenchymal Stem Cells

Engelmayr Jr,G.C., Sales,V.L., Mayer Jr,J.E. and Sacks,M.S. (2006) Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart valve tissues. Biomaterials, 27, 6083-6095.

Murine Lung Samples

Fichtner-Feigl,S., Strober,W., Kawakami,K., Puri,R.K. and Kitani,A. (2006) IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β production and fibrosis. Nature Medicine, 12, 99-106.


Fujimoto, H., Gabazza, E. C., Taguchi, O., Nishii, Y., Nakahara, H., Bruno, N. E., Alessandro-Gabazza, C. N., Kasper, M., Yano, Y., and Nagashima, M. (2006) Thrombin-Activatable Fibrinolysis Inhibitor Deficiency Attenuates Bleomycin-Induced Lung Fibrosis. American Journal of Pathology 168, 1086-1096.

Porcine Aortic Smooth Muscle Cells

Gavish,L., Perez,L. and Gertz,S.D. (2006) Low-level laser irradiation modulates matrix metalloproteinase activity and gene expression in porcine aortic smooth muscle cells. Lasers Surg Med., 38, 779-786.

Porcine Bone Marrow Stromal Cells

Goh,J.C.H., Te Tay,P.D. and Sl Toh,P.D. (2006) Characterization of a Novel Polymeric Scaffold for Potential Application in Tendon/Ligament Tissue Engineering. Tissue Engineering, 12, 91-99.

Murine Mesangial and Proximal Tubular Cell Culture Supernatants

Han,K.H., Kang,Y.S., Han,S.Y., Jee,Y.H., Lee,M.H., Han,J.Y., Kim,H.K., Kim,Y.S. and Cha,D.R. (2006) Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats. Kidney International, 70, 111-120.

Human Kidney-2 Cell Culture Supernatants

Han,S.Y., Jee,Y.H., Han,K.H., Kang,Y.S., Kim,H.K., Han,J.Y., Kim,Y.S. and Cha,D.R. (2006) An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy. Nephrology Dialysis Transplantation, 21, 2406.

Human Keratinocyte and Fibroblast Artificial Dermis

Harrison,C.A., Gossiel,F., Layton,C.M., Bullock,A.J., Johnson,T., Ubrey Blumsohn,P.D. and Sheila Macneil,P.D. (2006) Use of an in Vitro Model of Tissue-Engineered Skin to Investigate the Mechanism of Skin Graft Contraction. Tissue Engineering, 12, 3119-3113.

Leporine Temporomandibular Joint Disc Fibrocartilage, Knee Meniscus Fibrocartilage, Knee Articular Cartilage and Pubic Symphysis

Hashem,G., Zhang,Q., Hayami,T., Chen,J., Wang,W. and Kapila,S. (2006) Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis Res Ther., 8, R98.

Equine Superficial Digital Flexor Tendon in Explant Culture

Haupt,JL., Donnelly,BP. and Nixon,AJ. (2006) Effects of platelet-derived growth factor-BB on the metabolic function and morphologic features of equine tendon in explants culture. Am J Vet Res, 67, 1595-1600.

Human Osteoblast-Like SaOS-2 Cell Line

Huh,J.E., Yang,H.R., Park,D.S., Choi,D.Y., Baek,Y.H., Cho,E.M., Cho,Y.J., Kang-Il,K., Kim,D.Y. and Lee,J.D. (2006) Puerariae radix promotes differentiation and mineralization in human osteoblast-like SaOS-2 cells. J Ethnopharmacol, 104, 345-350.

Murine Pulmonary Myofibroblasts

Izumi,N., Mizuguchi,S., Inagaki,Y., Saika,S., Kawada,N., Nakajima,Y., Inoue,K., Suehiro,S., Friedman,S.L. and Ikeda,K. (2006) BMP-7 opposes TGF-β1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2. American Journal of Physiology- Lung Cellular and Molecular Physiology, 290, 120-126.


Jacono,F.J., Peng,Y.J., Nethery,D., Faress,J.A., Lee,Z., Kern,J.A. and Prabhakar,N.R. (2006) Acute lung injury augments hypoxic ventilatory response in the absence of systemic hypoxemia. Journal of Applied Physiology, 101, 1795.


Kato,T., Okahashi,N., Ohno,T., Inaba,H., Kawai,S. and Amano,A. (2006) Effect of phenytoin on collagen accumulation by human gingival fibroblasts exposed to TNF-ain vitro. Oral Diseases, 12, 156-162.

Human Alveolar Epithelial (A549) and Akata Cell Lines

Keating,D.T., Sadlier,D.M., Patricelli,A., Smith,S.M., Walls,D., Egan,J.J. and Doran,P.P. (2006) Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells. Respiratory Research, 7, 114.

Murine Kidneys

Kellner,D., Chen,J., Richardson,I., Seshan,S.V., EL Chaar,M., Vaughan Jr,E.D., Poppas,D. and Felsen,D. (2006) Angiotensin receptor blockade decreases fibrosis and fibroblast expression in a rat model of unilateral ureteral obstruction. J Urol, 176, 806-812.

Murine Kidney Cortex

Kushibiki,T., Nagata-Nakajima,N., Sugai,M., Shimizu,A. and Tabata,Y. (2006) Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-beta type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds. J Control Release, 110, 610-617.

Murine Tracheal Homogenates

Lama,V.N., Harada,H., Badri,L.N., Flint,A., Hogaboam,C.M., McKenzie,A., Martinez,F.J., Toews,G.B., Moore,B.B. and Pinsky,D.J. (2006) Obligatory Role for Interleukin-13 in Obstructive Lesion Development in Airway Allografts. American Journal of Pathology, 169, 47.

Human ER-Positive Breast Cancer MCF-7 Cell Line and Murine Osteoblast-Like MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2006) Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3-E1 cells. Phytother.Res, 20, 952-960.

Murine Osteoblast-Like MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2006) Rubus coreanus Miq. Extract Promotes Osteoblast Differentiation and Inhibits Bone-Resorbing Mediators in MC3T3-E1 Cells. The American Journal of Chinese Medicine, 34, 643-654.


Lee,K.S., Park,S.J., Kim,S.R., Min,K.H., Jin,S.M., Lee,H.K. and Lee,Y.C. (2006) Modulation of Airway Remodeling and Airway Inflammation by Peroxisome Proliferator-Activated Receptor γ in a Murine Model of Toluene Diisocyanate-Induced Asthma. The Journal of Immunology, 177, 5248.

Murine Liver Tissue

Lee,T.H., Jawan,B., Chou,W.Y., Lu,C.N., Wu,C.L., Kuo,H.M., Concejero,A.M. and Wang,C.H. (2006) alpha-Melanocyte-stimulating hormone gene therapy reverses carbon tetrachloride induced liver fibrosis in mice. J Gene Med, 8, 764-772.


Lee,J.H., Roh,M.R. and Lee,K.H. (2006) Effects of Infrared Radiation on Skin Photo-Aging and Pigmentation. Yonsei Med J., 47, 485-490.

Murine Bone Marrow Stromal Cells and Osteoblasts

Leivo,J., Meretoja,V., Vippola,M., Levanen,E., Vallittu,P. and Mantyla,T.A. (2006) Sol-gel derived aluminosilicate coatings on alumina as substrate for osteoblasts. Acta Biomater. 2, 659-668.

Human Skin Fibroblasts

Li,B., Chen,J. and James,H.C.W. (2006) RGD peptide-conjugated poly (dimethylsiloxane) promotes adhesion, proliferation, and collagen secretion of human fibroblasts. Mater Res, 79, 989-998.

Murine Cardiac Fibroblasts

Lijnen,P., Papparella,I., Petrov,V., Semplicini,A. and Fagard,R. (2006) Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species. J Hypertens, 24, 757-766.

Murine Hepatocytes and Hepatic Stellate Cells

Lin,Y.L., Wu,C.H., Luo,M.H., Huang,Y.J., Wang,C.N., Shiao,M.S. and Huang,Y.T. (2006) In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells. Journal of Ethnopharmacology, 105, 215-222.

Murine Lung Tissue

Liu,H., Liu,L., Fletcher,B.S. and Visner,G.A. (2006) Sleeping Beauty-based gene therapy with indoleamine 2, 3-dioxygenase inhibits lung allograft fibrosis. The FASEB Journal, 20, 2384.

Murine Lung Tissue

Lopez,E., del Pozo,V., Miguel,T., Sastre,B., Seoane,C., Civantos,E., Llanes,E., Baeza,M.L., Palomino,P. and Cardaba,B. (2006) Inhibition of Chronic Airway Inflammation and Remodeling by Galectin-3 Gene Therapy in a Murine Model 1. The Journal of Immunology, 176, 1943-1950.

Murine Lung Tissue

Ma,B., Blackburn,M.R., Lee,C.G., Homer,R.J., Liu,W., Flavell,R.A., Boyden,L., Lifton,R.P., Sun,C.X. and Young,H.W. (2006) Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. Journal of Clinical Investigation, 116, 1274-1283.

Human Dermal Fibroblast Primary and CRL-2127 Cell Cultures

Makareeva,E., Cabral,W.A., Marini,J.C. and Leikin,S. (2006) Molecular Mechanism of Alpha 1(I)-Osteogenesis Imperfecta/Ehlers-Danlos Syndrome: Unfolding of an N-Anchor Domain at the N-Terminal End of the Type I Collagen Triple Helix. Journal of Biological Chemistry, 281, 6463.

Murine Lung Tissue

Manoury,B., Nenan,S., Guenon,I., Boichot,E., Planquois,J.M., Bertrand,C.P. and Lagente,V. (2006) Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice. J Inflamm (Lond), 3, 2.


McFarlin,K., Gao,X., Liu,Y.B., Dulchavsky,D.S., Kwon,D., Arbab,A.S., Bansal,M., Li,Y., Chopp,M. and Dulchavsky,S.A. (2006) Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat. Wound Repair and Regeneration, 14, 471-478.

Leporine Bone Marrow-Derived Mesenchymal Stem Cells

Medrado,G.C.B., Machado,C.B., Valerio,P., Sanches,M.D. and Goes,A.M. (2006) The effect of a chitosan-gelatin matrix and dexamethasone on the behavior of rabbit mesenchymal stem cells. Biomedical Materials, 1, 155-161.

Murine Rectal Tissue

Motomura,Y., Khan,W.I., El-Sharkawy,R.T., Verma-Gandhu,M., Verdu,E.F., Gauldie,J. and Collins,S.M. (2006) Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1. Gut, 55, 662-670.

Human Lung Fibroblastic Cell Line TIG-3-20

Nagano, J., Iyonaga, K., Kawamura, K., Yamashita, A., Ichiyasu, H., Okamoto, T., Suga, M., Sasaki, Y., and Kohrogi, H. (2006) Use of tacrolimus, a potent antifibrotic agent, in bleomycin-induced lung fibrosis. European Respiratory Journal, 27, 460-469.


Narita,Y., Nomura,J., Ohta,S., Inoh,Y., Suzuki,K.M., Araki,Y., Okada,S., Matsumoto,I., Isohama,Y. and Abe,K. (2006) Royal Jelly Stimulates Bone Formation: Physiologic and Nutrigenomic Studies with Mice and Cell Lines. Bioscience, Biotechnology, and Biochemistry, 70, 2508-2514.

Murine Lung Tissue

Oikonomou,N., Harokopos,V., Zalevsky,J., Valavanis,C., Kotanidou,A., Szymkowski,D.E., Kollias,G. and Aidinis,V. (2006) Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis. PLoS ONE, 1, e108.

Murine Osteoblast Primay Cultures

Oktar,F.N., Valério,P., Goller,G., Agathopoulos,S., Goes,A.M. and Leite,M.F. (2006) Biocompatibility of the Outer Prismatic and the Inner Nacreous Layers of Four Different Molluscs. Key Engineering Materials, 309, 449.

Human Ligament Fibroblasts Primary Culture

Park,S.A., Kim,I.A., Lee,Y.J., Shin,J.W., Kim,C.R., Kim,J.K., Yang,Y.I. and Shin,J.W. (2006) Biological Responses of Ligament Fibroblasts and Gene Expression Profiling on Micropatterned Silicone Substrates Subjected to Mechanical Stimuli. Journal of Bioscience and Bioengineering, 102, 402-412.

Murine Hepatic Stellate Cells

Patella,S., Phillips,D.J., Tchongue,J., de Kretser,D.M. and Sievert,W. (2006) Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis. American Journal of Physiology- Gastrointestinal and Liver Physiology, 290, 137-144.

Human Fibroblast HFL-1 and Epithelial A549 Cell Line Co-Cultures

Phillips,R.J., Blatt,L.M. and Ozes,O.N. (2006) Pirfenidone and Interferon Gamma-1b Inhibit the Profibrotic Effects of Osteopontin. Chest, 130, 229S.

Murine Lung Tissue

Polte,T., Foell,J., Werner,C., Hoymann,H.G., Braun,A., Burdach,S., Mittler,R.S. and Hansen,G. (2006) CD137-mediated immunotherapy for allergic asthma. Journal of Clinical Investigation, 116, 1025-1036.

Human Mesenchymal Populations and Articular Chondrocytes

Pound,J.C., Green,D.W., Chaudhuri,J.B., Mann,S., Roach,H.I. and Oreffo,R.O.C. (2006) Strategies to Promote Chondrogenesis and Osteogenesis from Human Bone Marrow Cells and Articular Chondrocytes Encapsulated in Polysaccharide Templates. Tissue Engineerig, 12, 2789-2799.

Murine Cardiac Tissue

Reyes,M., Steinhelper,M.E., Alvarez,J.A., Escobedo,D., Pearce,J., Valvano,J.W., Pollock,B.H., Wei,C.L., Kottam,A. and Altman,D. (2006) Impact of physiological variables and genetic background on myocardial frequency-resistivity relations in the intact beating murine heart. American Journal of Physiology- Heart and Circulatory Physiology, 291, H1659.

Murine Fibroblast and Macrophage Co-Cultures

Saika, S., Ikeda, K., Yamanaka, O., Flanders, K. C., Okada, Y., Miyamoto, T., Kitano, A., Ooshima, A., Nakajima, Y., and Ohnishi, Y. (2006) Loss of Tumor Necrosis Factor α Potentiates Transforming Growth Factor β-mediated Pathogenic Tissue Response During Wound Healing. American Journal of Pathology 168, 1848-1860.

Ovine Blood-Derived Endothelial Progenitor Cells

Sales,V.L., Engelmayr Jr,G.C., Mettler,B.A., Johnson Jr,J.A., Sacks,M.S. and Mayer Jr,J.E. (2006) Transforming Growth Factor-β1 Modulates Extracellular Matrix Production, Proliferation, and Apoptosis of Endothelial Progenitor Cells in Tissue-Engineering Scaffolds. Circulation, 114, 1193-1199.

Murine Liver Tissue

Sato,Y., Harada,K., Furubo,S., Kizawa,K., Sanzen,T., Yasoshima,M., Ozaki,S., Isse,K., Sasaki,M. and Nakanuma,Y. (2006) Inhibition of Intrahepatic Bile Duct Dilation of the Polycystic Kidney Rat with a Novel Tyrosine Kinase Inhibitor Gefitinib. American Journal of Pathology, 169, 1238.

Porcine Cardiac Valve Leaflets

Schenke-Layland, K., Madershahian, N., Riemann, I., Starcher, B., Halbhuber, K. J., Konig, K., and Stock, U. A. Impact of Cryopreservation on Extracellular Matrix Structures of Heart Valve Leaflets. The Annals of Thoracic Surgery 81, 918-926.

Human Primary Fibroblast Cultures from Scleroderma Patients

Sherriff-Tadano,R., Ohta,A., Morito,F., Mitamura,M., Haruta,Y., Koarada,S., Tada,Y., Nagasawa,K. and Ozaki,I. (2006) Antifibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism. Modern Rheumatology, 16, 364-371.

Murine Lung Tissue

Shim,Y.M., Zhu,Z., Zheng,T., Lee,C.G., Homer,R.J., Ma,B. and Elias,J.A. (2006) Role of 5-Lipoxygenase in IL-13-Induced Pulmonary Inflammation and Remodeling. The Journal of Immunology, 177, 1918.

Porcine Heart Valves

Stock,U.A., Degenkolbe,I., Attmann,T., Schenke-Layland,K., Freitag,S. and Lutter,G. (2006) Prevention of device-related tissue damage during percutaneous deployment of tissue-engineered heart valves. The Journal of Thoracic and Cardiovascular Surgery, 131, 1323-1330.

Murine Lung Tissue and Bronchoalveolar Lavage Fluid

Sun,C.X., Zhong,H., Mohsenin,A., Morschl,E., Chunn,J.L., Molina,J.G., Belardinelli,L., Zeng,D. and Blackburn,M.R. (2006) Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury. Journal of Clinical Investigation, 116, 2173-2182.

Human Tendon Fibroblasts

Talwalkar,S.C., Evans,C.E., Trail,I.A. and McGrouther,D.A. (2006) Does Anatomical Location of a Tendon (Hand or Forearm) Influences Fibroblast Function in the Presence of Physical Forces. Journal of Bone and Joint Surgery – British Volume 88-B Supp. III:411.


Volmer,J.B., Thompson,L.F. and Blackburn,M.R. (2006) Ecto-5'-Nucleotidase (CD73)-Mediated Adenosine Production Is Tissue Protective in a Model of Bleomycin-Induced Lung Injury. The Journal of Immunology, 176, 4449-4458.

Murine Liver Tissue

Wang,C.H., Lee,T.H., Lu,C.N., Chou,W.Y., Hung,K.S., Concejero,A.M. and Jawan,B. (2006) Electroporative alpha-MSH gene transfer attenuates thioacetamide-induced murine hepatic fibrosis by MMP and TIMP modulation. Gene Therapy, 13, 1000-1009.

Bovine Annulus Fibrosus Primary Cell Culture

Wilda,H. and Gough,J.E. (2006) In vitro studies of annulus fibrosus disc cell attachment, differentiation and matrix production on PDLLA/45S5 Bioglass composite films. Biomaterials, 27, 5220-5229.


Wu,G.L.D.M. and Varga,J. (2006) Increased Bleomycin-Induced Skin Fibrosis in Mice Lacking the Th1-Specific Transcription Factor T-bet. Pathobiology, 73, 224-237.


Yasuoka,H., Jukic,D.M., Zhou,Z., Choi,A.M. and Feghali-Bostwick,C.A. (2006) Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis. Arthritis Rheum, 54, 3001-3010.

2005

Murine Lung Explant

Aono,Y., Nishioka,Y., Inayama,M., Ugai,M., Kishi,J., Uehara,H., Izumi,K. and Sone,S. (2005) Imatinib as a Novel Antifibrotic Agent in Bleomycin-induced Pulmonary Fibrosis in Mice. American Journal of Respiratory and Critical Care Medicine, 171, 1279.

Murine Lung Explants

Azuma,A., Li,Y.J., Abe,S., Usuki,J., Matsuda,K., Henmi,S., Miyauchi,Y., Ueda,K., Izawa,A. and Sone,S. (2005) Interferon-β Inhibits Bleomycin-Induced Lung Fibrosis by Decreasing Transforming Growth Factor-β and Thrombospondin. American Journal of Respiratory Cell and Molecular Biology, 32, 93-98.


Barbarin,V., Xing,Z., Delos,M., Lison,D. and Huaux,F. (2005) Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles. American Journal of Physiology- Lung Cellular and Molecular Physiology, 288, 841-848.


Beamer,C.A. and Holian,A. (2005) Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure. American Journal of Physiology- Lung Cellular and Molecular Physiology, 289, 186-195.


Burdick,M.D., Murray,L.A., Keane,M.P., Xue,Y.Y., Zisman,D.A., Belperio,J.A. and Strieter,R.M. (2005) CXCL11 Attenuates Bleomycin-induced Pulmonary Fibrosis via Inhibition of Vascular Remodeling. American Journal of Respiratory and Critical Care Medicine, 171, 261.

Human Fibroblasts

Cabral,W.A., Makareeva,E., Colige,A., Letocha,A.D., Ty,J.M., Yeowell,H.N., Pals,G., Leikin,S. and Marini,J.C. (2005) Mutations Near Amino End of alpha 1(I) Collagen Cause Combined Osteogenesis Imperfecta/Ehlers-Danlos Syndrome by Interference with N-propeptide Processing. Journal of Biological Chemistry, 280, 19259-19269.

Human to Mouse Cardiac Allografts

Campbell,L.G., Ramachandran,S., Liu,W., Shipley,J.M., Itohara,S., Rogers,J.G., Moazami,N., Senior,R.M. and Jaramillo,A. (2005) Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection. Am J Transplant, 5, 517-528.

Human Dental Pulp Cells

Chan,C.P., Lan,W.H., Chang,M.C., Chen,Y.J., Lan,W.C., Chang,H.H. and Jeng,J.H. (2005) Effects of TGF-βs on the growth, collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro. Archives of Oral Biology, 50, 469-479.


Chen,Q., Rabach,L., Noble,P., Zheng,T., Lee,C.G., Homer,R.J. and Elias,J.A. (2005) IL-11 Receptor a in the Pathogenesis of IL-13-Induced Inflammation and Remodeling 1. The Journal of Immunology, 174, 2305-2313.

Human Periodontal Fibroblasts

Chen,Y.J., Jeng,J.H., Jane Yao,C.C., Chen,M.H., Hou,L.T. and Lan,W.H. (2005) Long-term effect of pulsed Nd: YAG laser irradiation on cultured human periodontal fibroblasts. Lasers in Surgery and Medicine, 36, 225-233.


Choi,E.M. (2005) The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells. Biochem Pharmacol, 70, 363-368.


Chunn,J.L., Molina,J.G., Mi,T., Xia,Y., Kellems,R.E. and Blackburn,M.R. (2005) Adenosine-Dependent Pulmonary Fibrosis in Adenosine Deaminase-Deficient Mice 1. The Journal of Immunology, 175, 1937-1946.


Comporti,M., Arezzini,B., Signorini,C., Sgherri,C., Monaco,B. and Gardi,C. (2005) F2-isoprostanes stimulate collagen synthesis in activated hepatic stellate cells: a link with liver fibrosis?’ Laboratory Investigation, 85, 1381-1391.

Equine Tendons

Dahlgren,L., Mohammed,H. and Nixon,A. (2005) Temporal expression of growth factors and matrix molecules in healing tendon lesions. Journal of Orthopaedic Research, 23, 84-92.

Murine Thrombi

Deatrick,K.B., Eliason,J.L., Lynch,E.M., Moore,A.J., Dewyer,N.A., Varma,M.R., Pearce,C.G., Upchurch,G.R., Wakefield,T.W. and Henke,P.K. (2005) Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model. J Vasc Surg, 42, 140-148.

Murine Abdominal Wall Samples

DuBay,D.A., Wang,X., Adamson,B., Kuzon,W.M., Dennis,R.G. and FRANZ,M.G. (2005) Progressive fascial wound failure impairs subsequent abdominal wall repairs: A new animal model of incisional hernia formation. Surgery, 137, 463-471.

Simian Renal Fibroblasts (NRK-49F)

El Chaar,M., Attia,E., Chen,J., Hannafin,J., Poppas,D.P. and Felsen,D. (2005) Cyclooxygenase-2 Inhibitor Decreases Extracellular Matrix Synthesis in Stretched Renal Fibroblasts. Nephron Exp Nephrol, 100, 150-155.

Ovine Vascular Smooth Muscle Cells

Engelmayr,G.C., Mayer,J.E., Rabkin,E., Sacks,M.S., Schoen,F.J. and Sutherland,F.W.H. (2005) The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Biomaterials, 26, 175-187.

Murine Colon Homogenate

Fichtner-Feigl,S., Fuss,I.J., Preiss,J.C., Strober,W. and Kitani,A. (2005) Treatment of murine Th1-and Th2-mediated inflammatory bowel disease with NF-κB decoy oligonucleotides. Journal of Clinical Investigation, 115, 3057-3071.

Ovine Mesenchymal Progenitor Cells and Fetal Chondrocytes

Fuchs, J. R., Hannouche, D., Terada, S., Zand, S., Vacanti, J. P., and Fauza, D. O. (2005) Cartilage Engineering from Ovine Umbilical Cord Blood Mesenchymal Progenitor Cells. Stem Cells 23, 958-964.

Murine Fibroblasts and Mesenchymal Stem Cells

Ge,Z., Goh,J.C.H. and Lee,E.H. (2005) Selection of Cell Source for Ligament Tissue Engineering. Cell Transplantation, 14, 573-583.

Murine Lung Biopsies

Genovese,T., Cuzzocrea,S., Di Paola,R., Failla,M., Mazzon,E., Sortino,M.A., Frasca,G., Gili,E., Crimi,N. and Caputi,A.P. (2005) Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. Respir Res, 6, 58.

Porcine Anterior Cruciate Ligaments

Harrison,R.D. (2005) Effect of Extraction Protocols and Epidermal Growth Factor on the Cellular Repopulaton of Decellularized Anterior Cruciate Ligament Allografts. Biomed Mater Res A,75, 841-854.

Murine Hepatic Stellate cells (HSC-T6) and Liver Samples

Hsu,Y.C., Lin,Y.L., Chiu,Y.T., Shiao,M.S., Lee,C.Y. and Huang,Y.T. (2005) Antifibrotic effects of Salvia miltiorrhiza on dimethylnitrosamine-intoxicated rats. Journal of Biomedical Science, 12, 185-195.

Rat Left Ventricle

Iwata,K., Sawa,Y., Kitagawa-Sakakida,S., Kawaguchi,N., Matsuura,N., Nakamura,T. and Matsuda,H. (2005) Gene transfection of hepatocyte growth factor attenuates the progression of cardiac remodeling in the hypertrophied heart. The Journal of Thoracic and Cardiovascular Surgery, 130, 719-725.


Kato,T., Okahashi,N., Kawai,S., Kato,T., Inaba,H., Morisaki,I. and Amano,A. (2005) Impaired Degradation of Matrix Collagen in Human Gingival Fibroblasts by the Antiepileptic Drug Phenytoin. J Periodontol, 76, 941-950.

Human Periodontal Ligament Cell Cultures

Kawase,T., Okuda,K., Saito,Y. and Yoshie,H. (2005) In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or platelet-derived growth factor. J Periodontol, 76, 760-767.

Cadaveric Human Lumbar Intervertebral Discs

Keshari,K.R., Lotz,J.C., Kurhanewicz,J. and Majumdar,S. (2005) Correlation of HR-MAS Spectroscopy Derived Metabolite Concentrations With Collagen and Proteoglycan Levels and Thompson Grade in the Degenerative Disc. Spine, 30, 2683-2688.

Human Myocardial Samples

Klotz, S., Foronjy, R. F., Dickstein, M. L., Gu, A., Garrelds, I. M., Jan Danser, A. H., Oz, M. C., D'Armiento, J., and Burkhoff, D. (2005) Mechanical Unloading During Left Ventricular Assist Device Support Increases Left Ventricular Collagen Cross-Linking and Myocardial Stiffness. Circulation 112, 364-374.

Porcine Aortic Valves in Culture

Konduri,S., Xing,Y., Warnock,J.N., He,Z. and Yoganathan,A.P. (2005) Normal Physiological Conditions Maintain the Biological Characteristics of Porcine Aortic Heart Valves: An Ex Vivo Organ Culture Study. Annals of Biomedical Engineering, 33, 1158-1166.

Murine Kidney Cortex

Kushibiki,T., Nagata-Nakajima,N., Sugai,M., Shimizu,A. and Tabata,Y. (2005) Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis. J Control Release, 105, 318-331.

Murine Dermal Fibroblasts

Lateef,H., Aslam,M.N., Stevens,M.J. and Varani,J. (2005) Pretreatment of diabetic rats with lipoic acid improves healing of subsequently-induced abrasion wounds. Archives of Dermatological Research, 297, 75-83.

Murine Granulomas

Layland,L.E., Wagner,H. and Prazeres da Costa,C. (2005) Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/-mice. Eur.J.Immunol, 35, 3248-3257.

Human Ligament Fibroblasts

Lee,C.H., Shin,H.J., Cho,I.H., Kang,Y.M., Kim,I.A., Park,K.D. and Shin,J.W. (2005) Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials, 26, 1261-1270.


Lee,K.H. and Choi,E.M. (2005) Biochanin A Stimulates Osteoblastic Differentiation and Inhibits Hydrogen Peroxide-Induced Production of Inflammatory Mediators in MC3T3-E1 Cells. Biological & Pharmaceutical Bulletin, 28, 1948-1953.

Murine Lung Tissue Supernatant

Liu,H., Drew,P., Gaugler,A.C., Cheng,Y. and Visner,G.A. (2005) Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway. Am J Transplant, 5, 1256-1263.


Matsushita,M., Yamamoto,T. and Nishioka,K. (2005) Plasminogen activator inhibitor-1 is elevated, but not essential, in the development of bleomycin-induced murine scleroderma. Clinical and Experimental Immunology, 139, 429-438.

Human Venous Myofibroblasts

Mol,A., van Lieshout,M.I., Dam-de Veen,C.G., Neuenschwander,S., Hoerstrup,S.P., Baaijens,F.P. and Bouten,C.V.C. (2005) Fibrin as a cell carrier in cardiovascular tissue engineering applications. Biomaterials, 26, 3113-3121.


Moore,B.B., Ballinger,M.N., White,E.S., Green,M.E., Herrygers,A.B., Wilke,C.A., Toews,G.B. and Peters-Golden,M. (2005) Bleomycin-Induced E Prostanoid Receptor Changes Alter Fibroblast Responses to Prostaglandin E2 1. The Journal of Immunology, 174, 5644-5649.

Cricetine Left Ventricles

Nakamura,T., Matsumoto,K., Mizuno,S., Sawa,Y., Matsuda,H. and Nakamura,T. (2005) Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts. American Journal of Physiology- Heart and Circulatory Physiology, 288, 2131-2139.

Human Lung Fibroblast Culture Supernatants

Nakoman,C., Resmi,H., Ay,O., Acikel,U., Atabey,N. and Güner,G. (2005) Effects of basic fibroblast factor (bFGF) on MMP-2, TIMP-2, and type-I collagen levels in human lung carcinoma fibroblasts. Biochimie, 87, 343-351.

Leporine Temporomandibular Joint Discs

Naqvi,T., Duong,T.T., Hashem,G., Shiga,M., Zhang,Q. and Kapila,S. (2005) Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants. Arthritis Res Ther, 7, R1-11.


Nethery,D.E., Moore,B.B., Minowada,G., Carroll,J., Faress,J.A. and Kern,J.A. (2005) Expression of mutant human epidermal receptor 3 attenuates lung fibrosis and improves survival in mice. Journal of Applied Physiology, 99, 298-307.

Human Atheromatous Plaques

Penz, S., Reininger, A. J., Brandl, R., Goyal, P., Rabie, T., Bernlochner, I., Rother, E., Goetz, C., Engelmann, B., and Smethurst, P. A. (2005) Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. The FASEB Journal 19, 898-909. 2005.

Porcine Chordae Tendineae

Ritchie, J., Warnock, J. N., and Yoganathan, A. P. (2005) Structural Characterization of the Chordae Tendineae in Native Porcine Mitral Valves. The Annals of Thoracic Surgery 80, 189-197.

Murine Osteoblast Primary Cultures

Sampaio,B.V., Göller,G., Oktar,F.N., Val rio,P., Goes,A.M. and Leite,M.F. (2005) Biocompatibility Evaluation of Three Different Titanium-Hydroxyapatite Composites. Key Eng.Mater, 284, 639-642.


Santiago,B., Gutierrez-Cañas,I., Dotor,J., Palao,G., Lasarte,J.J., Ruiz,J., Prieto,J., Borrbs-Cuesta,F., Pablos,J.L. and Biotech,D. (2005) Topical Application of a Peptide Inhibitor of Transforming Growth Factor-bold beta 1 Ameliorates Bleomycin-Induced Skin Fibrosis. Journal of Investigative Dermatology, 125, 450-455.

Murine Osteoblast Primary Cultures

Schainberg,APM., Özyeğin,LS., Kursuoğlu,P., Valério,P., Goes,AM. and Leite,MF. (2005) Biocompatibility evaluation of Zeolite compared to bone HA, calcium phosphate (Ca2PO4) and Eugenol Paste. Key Engineering Materials 284-286, 561-564.

Murine Lung Tissue

Strieter,R.M., Keane,M.P., Burdick,M.D., Sakkour,A., Murray,L.A. and Belperio,J.A. (2005) The role of CXCR2/CXCR2 ligands in acute lung injury. Curr.Drug Targets Inflamm.Allergy, 4, 299-303.

Human Hepatic Stellate LI90 Cell Line

Sugimoto,R., Enjoji,M., Nakamuta,M., Ohta,S., Kohjima,M., Fukushima,M., Kuniyoshi,M., Arimura,E., Morizono,S. and Kotoh,K. (2005) Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cells. Liver International, 25, 420-428.

Ovine Fetal and Adult Chondrocytes

Terada,S., Fuchs,J.R., Yoshimoto,H., Fauza,D.O. and Vacanti,J.P. (2005) In Vitro Cartilage Regeneration From Proliferated Adult Elastic Chondrocytes. Annals of Plastic Surgery, 55, 196-201.

Ovine Chondrocytes

Terada,S., Yoshimoto,H., Fuchs,J.R., Sato,M., Pomerantseva,I., Selig,M.K., Hannouche,D. and Vacanti,J.P. (2005) Hydrogel optimization for cultured elastic chondrocytes seeded onto a polyglycolic acid scaffold. J.Biomed.Mater.Res.75A, 907-916.

Murine Osteoblast Primary Culture

Valério,P., Guimarbes,M.H.R., Pereira,M.M., Leite,M.F. and Goes,A.M. (2005) Primary osteoblast cell response to sol-gel derived bioactive glass foams. Journal of Materials Science: Materials in Medicine, 16, 851-856.

Human Fibroblast Primary Culture

Vancheri,C., Gili,E., Failla,M., Mastruzzo,C., Salinaro,E.T., LoFurno,D., Pistorio,M.P., La Rosa,C., Caruso,M. and Crimi,N. (2005) Bradykinin differentiates human lung fibroblasts to a myofibroblast phenotype via the B2 receptor. The Journal of Allergy and Clinical Immunology, 116, 1242-1248.


Vittal, R., Horowitz, J. C., Moore, B. B., Zhang, H., Martinez, F. J., Toews, G. B., Standiford, T. J., and Thannickal, V. J. (2005) Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against Fibrotic Tissue Injury. American Journal of Pathology 166, 367-375.

Canine Arterial Tissue

Yamaguchi-Okada,M., Nishizawa,S., Koide,M. and Nonaka,Y. (2005) Biomechanical and phenotypic changes in the vasospastic canine basilar artery after subarachnoid hemorrhage. Journal of Applied Physiology, 99, 2045-2052.

Murine Pancreatic Tissue

Yoo,B.M., Yeo,M., Oh,T.Y., Choi,J.H., Kim,W.W., Kim,J.H., Cho,S.W., Kim,S.J. and Hahm,K.B. (2005) Amelioration of pancreatic fibrosis in mice with defective TGF-beta signaling. Pancreas, 30, e71-e79.

Murine Pancreatic Tissue

Yoo,B.M., Oh,T.Y., Kim,Y.B., Yeo,M., Lee,J.S., Surh,Y.J., Ahn,B.O., Kim,W.H., Sohn,S. and Kim,J.H. (2005) Novel Antioxidant Ameliorates the Fibrosis and Inflammation of Cerulein-Induced Chronic Pancreatitis in a Mouse Model. Pancreatology, 5, 165-176.


Zhou,Y-j., Yin,D-m., Chen,H-s., Shi,J-h., Sha,B-x. and Wang,X. (2005) Inhibitory effects of idoxifene on hepatic fibrosis in rats. Acta Pharmacologia Sinica, 26, 581-586.

2004


Barbarin, V., Arras, M., Misson, P., Delos, M., McGarry, B., Phan, S. H., Lison, D., and Huaux, F. (2004) Characterization of the Effect of Interleukin-10 on Silica-Induced Lung Fibrosis in Mice. American Journal of Respiratory Cell and Molecular Biology 31, 78-85. 299.


Belperio,J.A., Dy,M., Murray,L., Burdick,M.D., Xue,Y.Y., Strieter,R.M. and Keane,M.P. (2004) The Role of the Th2 CC Chemokine Ligand CCL17 in Pulmonary Fibrosis 1. The Journal of Immunology, 173, 4692-4698.

Human Lung Tissue Samples and Murine Lung Homogenates

Berman,J.S., Serlin,D., Li,X., Whitley,G., Hayes,J., Rishikof,D.C., Ricupero,D.A., Liaw,L., Goetschkes,M. and O'Regan,A.W. (2004) Altered bleomycin-induced lung fibrosis in osteopontin-deficient mice. American Journal of Physiology- Lung Cellular and Molecular Physiology, 286, 1311-1318.

Murine Mammary Carcinoma MCa Cell Line

Casarsa,C., Mischis,M.T. and Sava,G. (2004) TGFbeta1 regulation and collagen-release-independent connective tissue re-modelling by the ruthenium complex NAMI-A in solid tumours. Journal of Inorganic Biochemistry, 98, 1648-1654.

Murine Lung Samples

Cho,J. (2004) ISS inhibits expression of MMP-9 and MMP-2 in a mouse model of airway remodeling. The Journal of Allergy and Clinical Immunology, 113, 92.

Human Patellar Tendon Fibroblasts

Cilli,F., Khan,M., Fu,F. and Wang,J.H. (2004) Prostaglandin E2 affects proliferation and collagen synthesis by human patellar tendon fibroblasts. Clin J Sport Med, 14, 232-236.

Human Pediatric Aortic Cells

Fu,P., Sodian,R., Luders,C., Lemke,T., Kraemer,L., Hubler,M., Weng,Y., Hoerstrup,S.P., Meyer,R. and Hetzer,R. (2004) Effects of basic fibroblast growth factor and transforming growth factor-beta on maturation of human pediatric aortic cell culture for tissue engineering of cardiovascular structures. ASAIO J, 50, 9-14.


Hattori, N., Mizuno, S., Yoshida, Y., Chin, K., Mishima, M., Sisson, T. H., Simon, R. H., Nakamura, T., and Miyake, M. (2004) The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism. American Journal of Pathology, 164, 1091-1098.

Murine Lung Samples

Honda,K., Marquillies,P., Capron,M. and Dombrowicz,D. (2004) Peroxisome proliferator-activated receptor γ is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. The Journal of Allergy and Clinical Immunology, 113, 882-888.

Murine Liver Tissues

Hsu,Y.C., Chiu,Y.T., Lee,C.Y., Lin,Y.L. and Huang,Y.T. (2004) Increases in fibrosis-related gene transcripts in livers of dimethylnitrosamine-intoxicated rats. Journal of Biomedical Science, 11, 408-417.

Murine Periodontal Ligament Cells

Inoue,M., LeGeros,R.Z., Hoffman,C., Diamond,K., Rosenberg,P.A. and Craig,R.G. (2004) Effect of enamel matrix proteins on the phenotype expression of periodontal ligament cells cultured on dental materials. Journal of Biomedical Materials Research, 69, 172-179.

Murine Osteoblast-like (MC3T3-E1) and Odontoblast-like (MDPC23) Cell Lines

Inoue,M., LeGeros,R.Z., Inoue,M., Tsujigiwa,H., Nagatsuka,H., Yamamoto,T. and Nagai,N. (2004) In vitro response of osteoblast-like and odontoblast-like cells to unsubstituted and substituted apatites. Journal of Biomedical Materials Research, 70, 585-593.


Kolodsick,J.E., Toews,G.B., Jakubzick,C., Hogaboam,C., Moore,T.A., McKenzie,A., Wilke,C.A., Chrisman,C.J. and Moore,B.B. (2004) Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts 1. The Journal of Immunology, 172, 4068-4076.

Murine Hepatic Stellate Cells and Liver Tissue and Human Hepatic Stellate (TWNT-4) Cell Line

Kotoh,K., Nakamuta,M., Kohjima,M., Fukushima,M., Morizono,S., Kobayashi,N., Enjoji,M. and Nawata,H. (2004) Arg-Gly-Asp (RGD) peptide ameliorates carbon tetrachloride-induced liver fibrosis via inhibition of collagen production and acceleration of collagenase activity. Int J Mol Med, 14, 1049-1053.

Human Fibroblast (NHDF) Cell Line

Koya-Miyata,S., Okamoto,I., Ushio,S., Iwaki,K., Ikeda,M. and Kurimoto,M. (2004) Identification of a Collagen Production-promoting Factor from an Extract of Royal Jelly and Its Possible Mechanism. Bioscience, Biotechnology, and Biochemistry, 68, 767-773.

Human Dermal Biopsy

Lateef, H., Stevens, M. J., and Varani, J. (2004) All-trans-Retinoic Acid Suppresses Matrix Metalloproteinase Activity and Increases Collagen Synthesis in Diabetic Human Skin in Organ Culture. American Journal of Pathology 165, 167-174.

Human and Murine Bone Marrow Stromal Fibroblasts

Lawson,M.A., Barralet,J.E., Wang,L., Shelton,R.M. and Triffitt,J.T. (2004) Adhesion and Growth of Bone Marrow Stromal Cells on Modified Alginate Hydrogels. Tissue Engineering, 10, 1480-1491.


Lee,C.G., Link,H., Baluk,P., Homer,R.J., Chapoval,S., Bhandari,V., Kang,M.J., Cohn,L., Kim,Y.K. and McDonald,D.M. (2004) Vascular endothelial growth factor (VEGF) induces remodeling and enhances T H 2-mediated sensitization and inflammation in the lung. Nature Medicine, 10, 1095-1103.

Leporine Chondrocytes

Lee,J. and Son,Y. (2004) TGF-beta Stimulates Conversion of Fibrocartilage Phenotype of Costal Chondrocytes. Tissue Eng.Reg.Med, 1, 171-177.

Human Embryonic Kidney (HEK-293, 293-EBNA and 293-T) Cell Lines and Human Fibrosarcoma (HT-1080) Cell Line

Leitinger,B., Steplewski,A. and Fertala,A. (2004) The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2. J Mol Biol, 344, 993-1003.

Human Cardiac Left Ventricle Tissue

Liang,H., Müller,J., Weng,Y.G., Wallukat,G., Fu,P., Lin,HS, Bartel,S., Knosalla,C., Pregla,R. and Hetzer,R.(2004) Changes in myocardial collagen content before and after left ventricular assist device

application in dilated cardiomyopathy. Chinese Medical Journal, 117, 401-407.


Mcmillan,S.J. and Lloyd,C.M. (2004) Prolonged allergen challenge in mice leads to persistent airway remodelling. Clinical & Experimental Allergy, 34, 497-507.

Human Colonic Tissue

Mimura,T., Bateman,A.C., Lee,R.L., Johnson,P.A., McDonald,P.J., Talbot,I.C., Kamm,M.A., MacDonald,T.T. and Pender,S.L.F. (2004) Up-Regulation of Collagen and Tissue Inhibitors of Matrix Metalloproteinase in Colonic Diverticular Disease. Diseases of the Colon & Rectum, 47, 371-379.


Nomura,Y., Taniguchi,M., Miyata,M., Ariyasu,T., Yamauchi,H., Ikeda,M. and Kurimoto,M. (2004) Interferon-gamma liniment protects hairless mice against ultraviolet irradiation-induced skin damage. Biomedical Research, 25, 277-285.

Murine Lung Tissue

Ono, M., Sawa, Y., Mizuno, S., Fukushima, N., Ichikawa, H., Bessho, K., Nakamura, T., and Matsuda, H. (2004) Hepatocyte Growth Factor Suppresses Vascular Medial Hyperplasia and Matrix Accumulation in Advanced Pulmonary Hypertension of Rats. Circulation, 110, 2896-2902.

Murine Gingival Fibroblasts

Paik,J.W., Kim,C.S., Cho,K.S., Chai,J.K., Kim,C.K. and Choi,S.H. (2004) Inhibition of cyclosporin A-induced gingival overgrowth by azithromycin through phagocytosis: an in vivo and in vitro study. J Periodontol, 75, 380-387.

Murine Lung Tissue

Phillips,R.J., Burdick,M.D., Hong,K., Lutz,M.A., Murray,L.A., Xue,Y.Y., Belperio,J.A., Keane,M.P. and Strieter,R.M. (2004) Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. Journal of Clinical Investigation, 114, 438-446.

Leporine Bronchoalveolar Lavage Fluid

Schmidt,R., Ruppert,C., Markart,P., Lubke,N., Ermert,L., Weissmann,N., Breithecker,A., Ermert,M., Seeger,W. and Gunther,A. (2004) Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis. Toxicology and Applied Pharmacology, 195, 218-231.

Ovine, Leporine and Murine Tissue Constructs

Shieh,S.J. and Terada,S. (2004) Tissue engineering auricular reconstruction: in vitro and in vivo studies. Biomaterials, 25, 1545-1557.

Bovine Collagen

Skilbeck,C.A., Walker,P.G., David,T. and Nash,G.B. (2004) Disturbed flow promotes deposition of leucocytes from flowing whole blood in a model of a damaged vessel wall. British Journal of Haematology, 126, 418-427.

Human Fibrosarcoma (HT-1080) Cell Line Procollagen

Steplewski,A., Ito,H., Rucker,E., Brittingham,R.J., Alabyeva,T., Gandhi,M., Ko,F.K., Birk,D.E., Jimenez,S.A. and Fertala,A. (2004) Position of single amino acid substitutions in the collagen triple helix determines their effect on structure of collagen fibrils. J Struct Biol, 148, 326-337.


Sue,R.D., Belperio,J.A., Burdick,M.D., Murray,L.A., Xue,Y.Y., Dy,M.C., Kwon,J.J., Keane,M.P. and Strieter,R.M. (2004) CXCR2 Is Critical to Hyperoxia-Induced Lung Injury 1. The Journal of Immunology, 172, 3860-3868.

Human Lymphoblast-like Jurkat D1.1 and E6-1 Cell Lines and Human Primary Fibroblast Lines

Suppl,A., Yurovsky,V.V. and White,B. (2004) Effect of CD154-CD40 interactions on collagen production by fibroblasts. Arthritis Res. 3A, P062.


Suzuki,M., Tanabe,F., Nakamura,S., Motoda,R. and Orita,K. (2004) NK-355, an aminovinyl photosensitizing dye, enhances collagen production through TGF-β1 upregulation. Journal of Dermatological Science, 34, 56-58.

Murine Brain Tissue

Tang,J., Liu,J., Zhou,C., Alexander,J.S., Nanda,A., Granger,D.N. and Zhang,J.H. (2004) MMP-9 Deficiency Enhances Collagenase-Induced Intracerebral Hemorrhage and Brain Injury in Mutant Mice. Journal of Cerebral Blood Flow & Metabolism, 24, 1133-1145.


Valerio,P., Pereira,M.M., Goes,A.M. and Leite,M.F. (2004) The effect of ionic products from bioactive glass dissolution on osteoblast proliferation and collagen production. Biomaterials, 25, 2941-2948.

Murine Thrombi

Varma,M.R., Moaveni,D.M., Dewyer,N.A., Varga,A.J., Deatrick,K.B., Kunkel,S.L., Upchurch Jr,G.R., Wakefield,T.W. and Henke,P.K. (2004) Deep vein thrombosis resolution is not accelerated with increased neovascularization. J Vasc Surg, 40, 536-542.

Murine Primary Hepatic Stellate Cell Line

Wada,W., Kuwano,H., Hasegawa,Y. and Kojima,I. (2004) The Dependence of Transforming Growth Factor-β-Induced Collagen Production on Autocrine Factor Activin A in Hepatic Stellate Cells. Endocrinology, 145, 2753-2759.


Watanabe,S., Nagashio,Y., Asaumi,H., Nomiyama,Y., Taguchi,M., Tashiro,M., Kihara,Y., Nakamura,H. and Otsuki,M. (2004) Pressure activates rat pancreatic stellate cells. American Journal of Physiology- Gastrointestinal and Liver Physiology, 287, 1175-1181.


Yamamoto,T. and Nishioka,K. (2004) Animal model of sclerotic skin. VI: Evaluation of bleomycin-induced skin sclerosis in nude mice. Archives of Dermatological Research, 295, 453-456.


Yamamoto,T. and Nishioka,K. (2004) Possible Role of Apoptosis in the Pathogenesis of Bleomycin-Induced Scleroderma. Journal of Investigative Dermatology, 122, 44-50.

Human Left Ventricle Tissue Biopsies

Zhang,J. and Narula,J. (2004) Molecular biology of myocardial recovery. Surg Clin North Am, 84, 223-242.

Human Pulmonary Fibroblasts

Zhang,L., Keane,M.P., Zhu,L.X., Sharma,S., Rozengurt,E., Strieter,R.M., Dubinett,S.M. and Huang,M. (2004) Interleukin-7 and Transforming Growth Factor-{beta} Play Counter-regulatory Roles in Protein Kinase C-{delta}-dependent Control of Fibroblast Collagen Synthesis in Pulmonary Fibrosis. Journal of Biological Chemistry, 279, 28315-28319.

2003


Blackburn,M.R., Lee,C.G., Young,H.W.J., Zhu,Z., Chunn,J.L., Kang,M.J., Banerjee,S.K. and Elias,J.A. (2003) Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. Journal of Clinical Investigation, 112, 332-344.

Trout Plasma, Endolymph and Otolith Explant

Borelli,G., Guibbolini,M.E., Mayer-Gostan,N., Priouzeau,F., De Pontual,H., Allemand,D., Puverel,S., Tambutte,E. and Payan,P. (2003) Daily variations of endolymph composition: relationship with the otolith calcification process in trout. Journal of Experimental Biology, 206, 2685-2692.

Human Fibroblasts

Cabral,W.A., Mertts,M.V., Makareeva,E., Colige,A., Tekin,M., Pandya,A., Leikin,S. and Marini,J.C. (2003) Type I Collagen Triplet Duplication Mutation in Lethal Osteogenesis Imperfecta Shifts Register of a Chains throughout the Helix and Disrupts Incorporation of Mutant Helices into Fibrils and Extracellular Matrix. Journal of Biological Chemistry, 278, 10006-10012.

Murine Lung Samples

Chung,MP., Monick,MM., Hamzeh,NY., Butler,NS., Powers,LS. and Hunninghake,GW. (2003) Role of repeated lung injury and genetic background in bleomycin-induced fibrosis. American Journal of Respiratory Cell and Molecular Biology 29, 375-380.


Denton,C.P., Zheng,B., Evans,L.A., Shi-wen,X., Ong,V.H., Fisher,I., Lazaridis,K., Abraham,D.J., Black,C.M. and de Crombrugghe,B. (2003) Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice. Journal of Biological Chemistry, 278, 25109-25119.

Human Atherosclerotic Plaques

Goncalves, I., Moses, J., Dias, N., Pedro, L. M., Fernandes e Fernandes, Nilsson, J., and Ares, M. P. S. (2003) Changes Related to Age and Cerebrovascular Symptoms in the Extracellular Matrix of Human Carotid Plaques. Stroke 34, 616-622.


Huaux,F., Liu,T., McGarry,B., Ullenbruch,M., Xing,Z. and Phan,S.H. (2003) Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis 1. The Journal of Immunology, 171, 5470-5481.

Murine Fibroblasts

Huaux,F., Liu,T., McGarry,B., Ullenbruch,M. and Phan,S.H. (2003) Dual Roles of IL-4 in Lung Injury and Fibrosis 1. The Journal of Immunology, 170, 2083-2092.

Murine Lung Hydrolysates

Hutson,P.R., Crawford,M.E. and Sorkness,R.L. (2003) Liquid chromatographic determination of hydroxyproline in tissue samples. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 791, 427-430.

Leporine Chondrocytes

Ibusuki,S., Fujii,Y., Iwamoto,Y. and Matsuda,T. (2003) Tissue-Engineered Cartilage Using an Injectable and in Situ Gelable Thermoresponsive Gelatin: Fabrication and in Vitro Performance. Tissue Engineering, 9, 371-384.

Murine Osteoblast-like MC3T3-E1 Cell Line

Luppen,C.A., Smith,E., Spevak,L., Boskey,A.L. and Frenkel,B. (2003) Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures. J Bone Miner Res, 18,1186-1197.

Murine Osteoblast-like MC3T3-E1 Subclone Cell Line

Luppen,C.A., Leclerc,N., Noh,T., Barski,A., Khokhar,A., Boskey,A.L., Smith,E. and Frenkel,B. (2003) Brief Bone Morphogenetic Protein 2 Treatment of Glucocorticoid-inhibited MC3T3-E1 Osteoblasts Rescues Commitment-associated Cell Cycle and Mineralization without Alteration of Runx2. Journal of Biological Chemistry, 278, 44995-45003.


Ohnishi, N., Miyata, T., Ohnishi, H., Yasuda, H., Tamada, K., Ueda, N., Mashima, H., and Sugano, K. (2003) Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis. Gut 52, 1487-1493.

Porcine, Ovine and Tissue-Engineered Cardiac Valve Leaflets

Schenke-Layland,K., Opitz,F., Gross,M., Döring,C., Halbhuber,K.J., Schirrmeister,F., Wahlers,T. and Stock,U.A. (2003) Complete dynamic repopulation of decellularized heart valves by application of defined physical signals - an in vitro study. Cardiovascular Research, 60, 497-509.


Suzuki, H., Aoshiba, K., Yokohori, N., and Nagai, A. (2003) Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Augments a Murine Model of Pulmonary Fibrosis 1. Cancer Research 63, 5054-5059.

Murine Thrombi

Thanaporn,P., Myers,D.D., Wrobleski,S.K., Hawley,A.E., Farris,D.M., Wakefield,T.W. and Henke,P.K. (2003) P-selectin inhibition decreases post-thrombotic vein wall fibrosis in a rat model. Surgery, 134, 365-371.


Valério,P., Goes,A.M., Pereira,M.M. and Leite,M.F. (2003) Cytological and biochemical evaluation of osteoblast in contact with ionic products of bioactive ceramics. Key Engineering Materials, 240, 703-706.

Murine Plasma

Vergnes,L., Phan,J., Strauss,M., Tafuri,S. and Reue,K. (2003) Cholesterol and Cholate Components of an Atherogenic Diet Induce Distinct Stages of Hepatic Inflammatory Gene Expression. Journal of Biological Chemistry, 278, 42774-42784.


Yamamoto,T. and Nishioka,K. (2003) Role of Monocyte Chemoattractant Protein-1 and its Receptor, CCR-2, in the Pathogenesis of Bleomycin-Induced Scleroderma. Journal of Investigative Dermatology, 121, 510-516.

Human Lung Fibroblast (8F1024, 8F1608 and 9F0892) Cell Lines

Yurovsky,VV. (2003) Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Enhances Collagen Production by Human Lung Fibroblasts. American Journal of Respiratory Cell and Molecular Biology, 28, 225-231.

2002


Blease, K., Schuh, J. M., Jakubzick, C., Lukacs, N. W., Kunkel, S. L., Joshi, B. H., Puri, R. K., Kaplan, M. H., and Hogaboam, C. M. (2002) Stat6-Deficient Mice Develop Airway Hyperresponsiveness and Peribronchial Fibrosis during Chronic Fungal Asthma. American Journal of Pathology 160(2), 481-490.

Human Pulmonary Fibrosis Fibroblasts, Normal Fibroblasts, U4A, U3A, and U4A/JAK1 Cell Lines and Murine Lung Samples

Huang,M., Sharma,S., Zhu,L.X., Keane,M.P., Luo,J., Zhang,L., Burdick,M.D., Lin,Y.Q., Dohadwala,M. and Gardner,B. (2002) IL-7 inhibits fibroblast TGF-β production and signaling in pulmonary fibrosis. Journal of Clinical Investigation, 109, 931-937.


Jain,V.V., Kitagaki,K., Businga,T., Hussain,I., George,C., O'Shaughnessy,P. and Kline,J.N. (2002) CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma. The Journal of Allergy and Clinical Immunology, 110, 867-872.

Murine Liver Samples

Kitamura,K., Nakamoto,Y., Akiyama,M., Fujii,C., Kondo,T., Kobayashi,K., Kaneko,S. and Mukaida,N. (2002) Pathogenic Roles of Tumor Necrosis Factor Receptor p55-Mediated Signals in Dimethylnitrosamine-Induced Murine Liver Fibrosis. Lab Invest, 82, 571-584.

Cultured Neonatal Heart Smooth-Muscle Cells

Langford,S.D., Trent,M.B. and Boor,P.J. (2002) Semicarbazide-sensitive amine oxidase and extracellular matrix deposition by smooth-muscle cells. Cardiovascular Toxicology, 2, 141-150.


Lanone,S., Zheng,T., Zhu,Z., Liu,W., Lee,C.G., Ma,B., Chen,Q., Homer,R.J., Wang,J. and Rabach,L.A. (2002) Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and-12 in IL-13-induced inflammation and remodeling. Journal of Clinical Investigation, 110, 463-474.

Murine Cardiac Samples

Li,Y.Y., Kadokami,T., Wang,P., McTiernan,C.F. and Feldman,A.M. (2002) MMP inhibition modulates TNF-a transgenic mouse phenotype early in the development of heart failure. American Journal of Physiology- Heart and Circulatory Physiology, 282, 983-989.

Murine Glomerular Mesangial Cells

Routh,R., McCarthy,K. and Welbourne,T. (2002) Troglitazone inhibits glutamine metabolism in rat mesangial cells. American Journal of Physiology- Endocrinology and Metabolism, 282, 231-238.

Murine Lung Tissue

Schuh,JM., Power,CA., Proudfoot,AE., Kunkel,SL, Lukacs,NW and Hogaboam,CM. (2002) Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to aspergillus in CCR4-/- mice. FASEB J. 16, 1313-1315.

Murine Lung Tissue

Suhara, H., Sawa, Y., Fukushima, N., Kagisaki, K., Yokoyama, C., Tanabe, T., Ohtake, S., and Matsuda, H. (2002) Gene transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension in rats. The Journal of Thoracic and Cardiovascular Surgery 123, 855-861.


Takeda,U., Utani,A., Wu,J., Adachi,E., Koseki,H., Taniguchi,M., Matsumoto,T., Ohashi,T., Sato,M. and Shinkai,H. (2002) Targeted Disruption of Dermatopontin Causes Abnormal Collagen Fibrillogenesis. Journal of Investigative Dermatology, 119, 678-683.


Yamamoto,T. and Nishioka,K. (2002) Analysis of the effect of halofuginone on bleomycin-induced scleroderma. Rheumatology, 41, 594-596.

2001

Bovine Chondrocytes

Amiel,G.E., Yoo,J.J., Kim,B.S. and Atala,A. (2001) Tissue engineered stents created from chondrocytes. J Urol, 165, 2091-2095.

Human Granulosa Cells

Aston,K.E., Stamouli,A., Thomas,E.J., Vyas,S., Iredale,J.P., Arthur,M.J.P. and Richardson,M.C. (2001) Endocrinology and paracrinology Effect of gonadotrophin on cell and matrix retention and expression of metalloproteinases and their inhibitor in cultured human granulosa cells modelling corpus luteum function. Molecular Human Reproduction, 2, 26-30.


Blease,K., Jakubzick,C., Schuh,J.M., Joshi,B.H., Puri,R.K. and Hogaboam,C.M. (2001) IL-13 Fusion Cytotoxin Ameliorates Chronic Fungal-Induced Allergic Airway Disease in Mice 1. The Journal of Immunology, 167, 6583-6592.

Trout and Turbot Endolymph and Otoliths

Borelli,G., Mayer-Gostan,N., De Pontual,H., Boeuf,G. and Payan,P. (2001) Biochemical Relationships Between Endolymph and Otolith Matrix in the Trout (Oncorhynchus mykiss) and Turbot (Psetta maxima). Calcified Tissue International, 69, 356-364.


Bouma,P., Cabral,W.A., Cole,W.G. and Marini,J.C. (2001) COL5A1 Exon 14 Splice Acceptor Mutation Causes a Functional Null Allele, Haploinsufficiency of a1 (V) and Abnormal Heterotypic Interstitial Fibrils in Ehlers-Danlos Syndrome II. Journal of Biological Chemistry, 276, 13356-13364.

Leporine Lens Epithelial Cells

Ishida,I., Saika,S. and Ohnishi,Y. (2001) Effect of minoxidil on rabbit lens epithelial cell behavior in vitro and in situ. Graefe's Archive for Clinical and Experimental Ophthalmology, 239, 770-777.

Leporine Lens Epithelial Cells

Ishida,I.K.U. (2001) Experimental study on the efficacy of minoxidil in preventing postoperative capsular opacification. Journal of the Wakayama Medical Society, 52, 207-215.


Lee,C.G., Homer,R.J., Zhu,Z., Lanone,S., Wang,X., Koteliansky,V., Shipley,J.M., Gotwals,P., Noble,P. and Chen,Q. (2001) Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1. Journal of Experimental Medicine, 194, 809-822.

Human Left Ventricle Samples

Li, Y. Y., Feng, Y., McTiernan, C. F., Pei, W., Moravec, C. S., Wang, P., Rosenblum, W., Kormos, R. L., and Feldman, A. M. (2001) Downregulation of Matrix Metalloproteinases and Reduction in Collagen Damage in the Failing Human Heart After Support With Left Ventricular Assist Devices. Circulation 104, 1147-1152.

Murine Renal Tissue

Mizuno,S., Matsumoto,K. and Nakamura,T. (2001) Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney International, 59, 1304-1314.

Rat Fetal Lung Fibroblast (RFL-6) Cell Line

Samimi,A. and Last,J.A. (2001) Inhibition of Lysyl Hydroxylase by Malathion and Malaoxon. Toxicology and Applied Pharmacology, 172, 203-209.

2000

Rat Aortic Smooth Muscle Cells and Pig Auricular Chondrocytes

Brown, AN., Kim, BS., Alsberg,E. And Mooney,DJ.(2000) Combining Chondrocytes and Smooth Muscle Cells to Engineer Hybrid Soft Tissue Constructs. Tissue Engineering, 6, 297-305.

Human Primary Fibroblast Cultures

Kurasawa,K., Hirose,K., Sano,H., Endo,H., Shinkai,H., Nawata,Y., Takabayashi,K. and Iwamoto,I. (2000) Increased interleukin-17 production in patients with systemic sclerosis. Arthritis & Rheumatism, 43, 2455-2463.

Murine Cardiac Left Ventricles

Li,Y.Y., Feng,Y.Q., Kadokami,T., McTiernan,C.F., Draviam,R., Watkins,S.C. and Feldman,A.M. (2000) Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy. Proceedings of the National Academy of Sciences, 97, 12746.

Murine Renal Tissue

Mizuno,S. (2000) Reciprocal balance of hepatocyte growth factor and transforming growth factor-β 1 in renal fibrosis in mice. Kidney International, 57, 937.


Tokuda,A., Itakura,M., Onai,N., Kimura,H., Kuriyama,T. and Matsushima,K. (2000) Pivotal Role of CCR1-Positive Leukocytes in Bleomycin-Induced Lung Fibrosis in Mice 1. The Journal of Immunology, 164, 2745-2751.

1999

Bovine Articular Chondrocyte Cultures

Ioannidis,N., Kurz,B., Hansen,U. and Schünke,M. (1999) Influence of fulvic acid on the collagen secretion of bovine chondrocytes in vitro. Cell and Tissue Research, 297, 141-147.

Murine Dermis Samples

Jimenez,P.A. and Rampy,M.A. (1999) Keratinocyte Growth Factor-2 Accelerates Wound Healing in Incisional Wounds. Journal of Surgical Research, 81, 238-242.

Murine Tail Tendon

Kuznetsova,N. and Leikin,S. (1999) Does the Triple Helical Domain of Type I Collagen Encode Molecular Recognition and Fiber Assembly while Telopeptides Serve as Catalytic Domains? Effect of Proteolytic Cleavage On Fibrillogenesis And On Collagen-Collagen Interaction In Fibers. Journal of Biological Chemistry, 274, 36083-36088.

Murine Liver Tissue

Natsume, M. (1999) Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6-deficient mice. Journal of Leukocyte Biology 66, 601-608.

Murine Bone Marrow Stromal Cells

Notoya,K., Nagai,H., Oda,T., Gotoh,M., Hoshino,T., Muranishi,H., Taketomi,S., Sohda,T. and Makino,H. (1999) Enhancement of Osteogenesis In Vitro and In Vivo by a Novel Osteoblast Differentiation Promoting Compound, TAK-778. Journal of Pharmacology and Experimental Therapeutics, 290, 1054-1064.

Murine Liver Tissue

Shimizu,I., Mizobuchi,Y., Yasuda,M., Shiba,M., Ma,Y.R., Horie,T., Liu,F. and Ito,S. (1999) Inhibitory effect of oestradiol on activation of rat hepatic stellate cells in vivo and in vitro. Gut, 44, 127-136.

Murine Liver Tissue and Primary cultures of Stellate cells and Hepatocytes

Shimizu,I., Ma,Y.R., Mizobuchi,Y., Liu,F., Miura,T., Nakai,Y., Yasuda,M., Shiba,M., Horie,T. and Amagaya,S. (1999) Effects of sho-saiko-to, a japanese herbal medicine, on hepatic fibrosis in rats. Hepatology, 29, 149-160.

Murine Liver Homogenate

Yasuda,M., Shimizu,I., Shiba,M. and Ito,S. (1999) Suppressive effects of estradiol on dimethylnitrosamine-induced fibrosis of the liver in rats. Hepatology, 29, 719-727.

1998

Human Osteoblasts

Andrade,A.L., Valqrio,P., Goes,A.M., Leite,M.F. and Domingues,R.Z. (1998) Behavior of Osteoblasts Cultured on Collagen Coated Bioactive Glass. Biomaterials, 19, 1019 – 1025.

Murine Tail Tendon

Knight,D.P., Nash,L., Hu,X.W., Haffegee,J. and Ho,M.W. (1998) In vitro formation by reverse dialysis of collagen gels containing highly oriented arrays of fibrils. Journal of Biomedical Materials Research, 41, 185-191.

Human Bone Marrow Fibroblastic Cells

Oreffo,R.O., Driessens,F.C., Planell,J.A. and Triffitt,J.T. (1998) Effects of novel calcium phosphate cements on human bone marrow fibroblastic cells. Tissue Eng, 4, 293-303.

Murine Aortic Explants

Tang,J., O'Callaghan,D., Rouy,S. and Godlewski,G. (1998) Quantitative changes in collagen levels following 830-nm diode laser welding. Lasers in Surgery and Medicine, 22, 207-211.

1997

Human Amniotic Membrane Samples

Hampson,V., Liu,D., Billett,E. and Kirk,S. (1997) Amniotic membrane collagen content and type distribution in women with preterm premature rupture of the membranes in pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 104, 1087-1091.

Murine Cardiac Ventricles

Lubec,B., Hjelm,M., Hoeger,H., Gialamas,J. and Lubec,G. (1997) 4-Thiaproline reduces heart lipid peroxidation and collagen accumulation in the diabetic db/db mouse. Amino Acids, 12, 343-351.

Murine Articular Cartilage

Nakamura,M., Watanabe,J., Ogawa,R. and Kanamura,S. (1997) Immunohistochemical localization of type II and type I collagens in articular cartilage of the femoral head of dexamethasone-treated rats. The Histochemical Journal, 29, 645-654.

Addendum (Citations with Undetermined Experimental Model)

Asaumi,H., Watanabe,S., Taguchi,M., Nagashio,Y., Nomiyama,Y., Tashiro,M., Kihara,Y. and Otsuki,M. (2004) Inhibition of pancreatic stellate cell activation by green tea catechin through anti-oxidative effect. Pancreas, 29, 351.

Heemskerk,J.W., Siljander,P., Vuist,W.M., Breikers,G., Reutelingsperger,C.P., Barnes,M.J., Knight,C.G., Lassila,R. and Farndale,R.W. (1999) Function of glycoprotein VI and integrin alpha2beta1 in the procoagulant response of single, collagen-adherent platelets. Thromb Haemost, 81, 782-792.

Hsia-Wei Liu,P.D., Chen,C.H.W.A., Tsai,C.L.I.N., Lin,I.H. and Hsiue,G.H.O. (2007) Heterobifunctional poly(ethylene glycol)-tethered bone morphogenetic protein-2-stimulated bone marrow mesenchymal stromal cell differentiation and osteogenesis. Tissue Eng., 13, 1113-1124.

Gomperts,B.N. and Strieter,R.M. (2007) Fibrocytes in Lung Disease. Journal of Leukocyte Biology, 82, 449.

Ito,H., Steplewski,A., Alabyeva,T. and Fertala,A. (2006) Testing the utility of rationally engineered recombinant collagen-like proteins for applications in tissue engineering. J.Biomed.Mater.Res, 76, 551-560.

Li,Y.Y. and Feldman,A.M. (2001) Matrix metalloproteinases in the progression of heart failure: potential therapeutic implications. Drugs, 61, 1239-1252.

Tüyel,A.U., Valério,P., Öner,E.T. and Oktar,F.N. (2009) Biological activities of bioceramic powders of various natural biological origins. New Biotechnology, 25, S28.

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