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Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

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Emotional Intelligence and Health Related Quality of Life Outcomes in Children with Sickle Cell Anemia Leeza Ali, Principal Investigator Dr. Pashankar and Dr. Kristi Lockhart: Primary Advisers Yale University
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Page 1: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Emotional Intelligence and Health Related Quality of Life Outcomes in Children with Sickle Cell Anemia

Leeza Ali, Principal InvestigatorDr. Pashankar and Dr. Kristi Lockhart: Primary Advisers

Yale University

Page 2: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Road Map Background:

Defining Emotional Intelligence How EI mediates mental and physical health

Methods

Results

Data Analysis: A Visual Representation

Future Directions

Page 3: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Background – Defining Emotional Intelligence Emotional Intelligence:

How individuals recognize, and regulate emotions in the self in others – coined by Peter Salovey

Trait vs. Ability EI – Self-reported perception of EI vs. ability based tests

Problems with EI: situational and cultural factors, real EI or ability to conform to social norms?

Page 4: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Emotional Intelligence and Health Strong Empirical Evidence Analyses – 105 effect sizes and 20,000

Participants – EI is associated with mental,

Physical, and psycosomatic health (Martins, 2010; Schutte, 2007).

Problem: Correlation vs. Causation Ill children never have the opportunity

to develop intepersonal skills and emotion

Related abilities? (Taylor, 2011)

Page 5: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Theoretical Frameworks Explaining EI’s Impact on Health

1. Adolescent human brains are especially sensitive to

the effects of elevated levels of glucocorticoids

and the heightening of the HPA reactivity induced

by high stress levels (2009). Thus, managing stress

Effectively is crucial and EI may mediate this process.

2. Changes in physiological responses to stress:

Higher EI attenuated cortisol secretion in

response to repeated stressors (Salovey).

3. Higher EI leads to higher levels of positive affect –

can better repair negative mood states, can better maximize impact of positive environmental cues. Broad-and-build theory: high PA broadens thought-action repertoire and builds personal, social, and psychological resources (Fredrickson, 2001).

4. Excess corticotrophin-releasing hormone and increased anxiety in anticipation for a stressful event contribute to “allostatic load”: the wear on tissues and an acceleration of pathophysiology arising from the body’s attempts to adapt to stress (Schulkin, 1998)

Page 6: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

The Role of EI in Children with Chronic Illness Cognitive decline with cranial irradiation targeted chemotherapy (Kreitler & Arush, 2004).

higher EI contributes to better health outcomes in cancer patients (Smith et al., 2012). However, the role of EI in sickle cell patients has never, to our knowledge, been explored.

Unlike pediatric cancer patients that display psychological hardiness and emotional resillience (Noll et al., 1999), sickle cell patients show poor psychosocial adjustment in response to the stress of their chronic illness (Hurtig & White, 1986).

sickle cell disease is associated with high incidence of neurological events and poor neuropsychological outcomes, including deficits in cognitive ability and academic performance (Berkelhammer et al., 2007).

Children growing up in a chronically stressful family environment may actually develop exaggerated sympathetic reactivity to stressors and amplified cortosol response to stressors (Taylor, 2011).

Exposure to chronic stress early in may cause developing stress systems to become dysregulated, such that neuroendocrine stress responses become dysfunctional (Taylor, 2011), producing problematic physical and psychosocial outcomes.

Page 7: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

MethodParticipants: 30 patients ages 8-20 diagnosed with SCD. Each patient takes 1 EI survey, the PedsQL4.0, and the PedsQL Sickle Cell module

The survey will be linked the MRN of participants, used to record:

Number of pain admissions in past two years

Total number of hospital days due to pain

Number of ER visits due to pain

Type of sickle cell disease,

history of ACS, stroke, social worker survey info

Page 8: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Preliminary Findings

Higher EQ scores have been highly correlated to: better physical functioning scale scores higher emotional functioning scale scores better core psychosocial health summary scores better school functioning scale scores. higher communication scores (perceived ability to communicate and express pain

accurately with doctors/caregivers) less pain intensity, pain interference and impact, and less worry.

Page 9: Broad.Haven.Leeza.Ali.Principal.Investigator.Yale.Clinical.Research.Symposium

Future Directions EI and Empathy Study – Summer 2015

Same patient cohort, designed with Dr. David Rand (New Yale Psychology Faculty member)

Dr. Rand’s specialty is cooperation and empathy – what makes some patients “cooperators” who always listen to doctors orders and what makes some patients “non-cooperators” who refuse to take medications regularly and show up to appointments? We believe one mediating factor is empathy – one of the 5 core areas of EI The ability to recognize and understand (empathize) with one’s doctor may motivate

patients to cooperate with their orders

EI In Patients with Other Chronic Illnesses: Continuation of this study with larger patient cohort (Cancers, other life threatening diseases) Also incorporate a control group of HEALTHY children

for comparison data