Bronchial Asthma

Andriy Lepyavko, MD, PhD

Department of Internal Medicine № 2

Methods of investigation

• Objectively: Tachypnoe with prolonged expiration, wheezing, dry rales

• Sputum analysis: eosinophils, Kurshman spirals (mucus from small bronchi), Sharko-Leiden crystals (enzymes of eosinophils)

• General blood analysis: mild leucocytosis, eosinophilia

• Spyrometry: decreased FVC, FEV1, FEV1/FVC, increased daily variability

Comparative Flow-Volume Loops at Asthma