Building Families Worldwide
Per Falk
President and Chief Science Officer
18th January 2019 CONFIDENTIAL
2
Our History
Eva and Frederik Paulsen
3
Our Mission Statement
Driven by its entrepreneurial spirit and enabled by a decentralised organisational setup,
Ferring will harness its world-class competencies in science and business with other
innovative technologies to create solutions for patients and doctors. By developing an
understanding of people’s needs, we will deliver personalised healthcare solutions,
integrating pharmaceutical products with diagnostics, data, devices, education and
support services to optimise health outcomes.
Ferring will be the world-leading, most trusted healthcare company in
reproductive medicine and women’s health, and a leader in specialty areas within
gastroenterology and urology. Each of us at Ferring will contribute to providing
innovative solutions to help people live better lives. We will devote significant research
and development investment to new therapeutics, life cycle management and next
generation healthcare solutions.
As a privately owned, specialty healthcare company that operates globally, Ferring will
grow revenues at a rate that is 50% faster than the industry average. We will strive for
efficiencies in our business and create flexibility to invest in opportunities to build our
future.
We are, and will continue to be, part of a transparent and aligned company. We strive to
best address the needs of patients, stakeholders and customers by collaborating across
functions, experimenting and sharing our practices, and continuously learning. We are
always guided by the Ferring Philosophy.
4
Our global presence
Distribution in 110
countries
Marketing and sales
in 56 countries
11 R&D centers
12 manufacturing sites
5
Innovation from conception to delivery
Menorrhagia
Down
regulation
Stimulation
ImplantationLuteal support
Pre-mature
labour
Induction
of labor
Post Partum
Hemorrhage
Lactation
Phase II
Phase II
Phase III
ResearchResearch, Device,
Geographical expansion
Research
Anovulation
Regulatory
Geographical expansion
PABAL® (OT agonist)
MISODEL® (PGE1 vaginal insert)
PROPESS® (PGE2 vaginal insert)
TRACTOCILE® (OT/V1a antagonist)
LYSTEDA® (Anti-fibrynolytic)
GONAPEPTYL® (GnRH agonist)
LUTINUS® (vaginal progesterone)
MILPROSA®
MENOPUR® (HP-hMG)
LUTREPULSE® (LHRH s.c. pump)
CHORAGON® (u-hCG)
NORPROLAC® (quinagolide hydrochloride)
REKOVELLE® (follitropin delta)
Ps female indications only noted on slide, these products also have male indications
Gynaecology
Fertility
Obstetrics
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Therapeutic area revenue contributions
€1.9 billion*
Reproductive
Medicine &
Women’s Health
Orthopaedics
Urology
Gastroenterology
Endocrinology
9%
5%
23%
16%
46%Other
1%
*2017 revenue
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R&D Investment per therapeutic area
*2017 revenue of €1.9 billion
~17% of revenue*
21%
20%
38%
22%REPRODUCTIVE MEDICINE
AND WOMEN’S HEALTH
UROLOGY
OTHER
GASTROENTEROLOGY
22%
38%
20%
21%
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Our mission
• Ferring has been developing treatments for mothers and
babies for over 50 yearsFerring will be the world-leading, most
trusted healthcare company in reproductive
medicine and women’s health
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Our ambition
Pioneer a new era in fertility
where all potential parents are
empowered to build families
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Our strategy
Optimizing our current assets in close collaboration with our customers to ensure delivery of maximum value to providers and patients
Developing and launching next generation therapies in Fertility, Obstetrics and Gynaecology indications impacting fertility
Improving access to care addressing patient, provider, payer, policy makers and societal needs by developing meaningful solutions in partnerships
Collaborations
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ReproUnion
• Collaboration between a network of 16 clinical and research units within the Capital Region of Denmark and Ferring Pharmaceuticals
• 16 Clinical/Research Units
• ±15 PI’s
• 25 Projects
• Investment of €15 million over three years
• 25 PhD students/Postdocs (19/6)
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Ferring Institute of Reproductive Medicine
25% of couples in China are
affected by infertility1 vs. 17% of
couples worldwide2
• Ferring’s long-term collaboration with CAS includes the creation of the Ferring Institute of Reproductive Medicine (FIRM) in Beijing, China
• Collaboration focuses on scientific research in reproductive medicine and women’s health that may lead to new treatments for fertility and pregnancy-related conditions
• Aim is to advance basic and translational research through the development of novel product candidates and therapeutic strategies
• FIRM will explore novel technologies in stem cell and regenerative medicine, and identify new targets for drug-discovery
1. Zhou Z, Zhang D, et al. Epidemiology of infertility in China: a population based study. British Journal of Obstetrics and
Gynaecology 2017. Available at: https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.14966.
2. European Society of Human Reproduction and Embryology. ART Factsheet. February 2018. Available at:
https://www.eshre.eu/Press-Room/Resources.aspx Last accessed: May 2018.
3. https://www.youtube.com/watch?v=sqG_7V7hwB0
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Collaborations in personalised medicine and genomics
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Reducing Maternal Mortality - CHAMPION
The global clinical trial compared the effectiveness and
safety of Ferring's heat-stable carbetocin
to oxytocin in the prevention of postpartum haemorrhage
(PPH) after vaginal births1,2
MSD for Mothers funded the trial and the Human Reproduction
Program at the World Health Organization
conducted the trial. Involving nearly 30,000 women
in 10 countries,1,2 CHAMPION is the largest clinical trial
ever conducted in PPH
We believe we could save thousands of lives and improve
the quality of life of women and their families by delivering
heat-stable carbetocin to countries that need it most
Excessive bleeding after childbirth, known as PPH, is
the leading direct cause of maternal mortality worldwide3
99% of deaths from PPH occur in low- and
lower-middle-income countries4
14,000,000women develop
PPH
every year4
480,000mothers died
from PPH
between
2003–20093
1. Widmer M, et al. Room temperature stable carbetocin for the prevention of postpartum haemorrhage during the third stage of labour in women delivering vaginally: study protocol for a randomized controlled trial. Trials 2016; 17(1):143. doi:
10.1186/s13063-016-1271-y
2. Australian New Zealand Clinical Trial Registry. Available at: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=366743 Last accessed: May 2018.
3. Say L, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Global Health 2014 Jun;2(6):e323-33.
4. World Health Organization. Priority diseases and reasons for inclusion. Postpartum haemorrhage. Available at: http://www.who.int/medicines/areas/priority_medicines/Ch6_16PPH.pdf Last accessed: May 2018.
CHAMPION (Carbetocin Haemorrhage Prevention)
Questions?