BLOOD VESSELS: VASCULITIS,TUMORS

Bacillary angiomatosis. A, Photograph of a cutaneous lesion. B, Histologic appearance with acute neutrophilic inflammation and vascular (capillary) proliferation. (Inset) Demonstration by modified silver (Warthin-Starry) stain of clusters of tangled bacilli (black).

Kaposi sarcoma. A, Gross photograph, illustrating coalescent red-purple macules and plaques of the skin. B, Histologic appearance of nodular form, demonstrating sheets of plump, proliferating spindle cells.

A,Gross photograph of angiosarcoma of the heart (right ventricle). B, Photomicrograph of moderately well-differentiated angiosarcoma with dense clumps of irregular, moderate anaplastic cells and distinct vascular lumens. C, Immunohistochemical staining for the endothelial cell marker CD31, demonstrating the endothelial nature of the tumor cells.

Balloon angioplasty and endovascular stents. A, Coronary artery after balloon angioplasty, showing the dissection encompassing the intima and media (arrow). B, Gross photograph of restenosis following balloon angioplasty, demonstrating residual atherosclerotic plaque (left arrow) and a new, glistening proliferative lesion (right arrow). C, Coronary arterial stent implanted long term, demonstrating thickened neointima separating the stent wires (black spot shown by arrow) from the lumen.

BENIGN NEOPLASMS, DEVELOPMENTAL AND ACQUIRED CONDITIONS Hemangioma Capillary hemangioma Cavernous hemangioma Pyogenic granuloma Lymphangioma Simple (capillary) lymphangioma Cavernous lymphangioma (cystic hygroma) Glomus tumor Vascular ectasias Nevus flammeus Spider telangiectasia (arterial spider) Hereditary hemorrhagic telangiectasis (Osler-Weber-Rendu disease) Reactive vascular proliferations Bacillary angiomatosis INTERMEDIATE-GRADE NEOPLASMS Kaposi sarcoma Hemangioendothelioma MALIGNANT NEOPLASMS Angiosarcoma Hemangiopericytoma

Hemangiomas. A, Hemangioma of the tongue. B and C, Histologic appearance of (B) juvenile capillary hemangioma and (C) cavernous hemangioma. D, Pyogenic granuloma of the lip.

Anastomotic hyperplasia at the distal anastomosis of synthetic femoropopliteal graft. A, Angiogram demonstrating constriction (arrow). B, Photomicrograph demonstrating Gore-Tex graft (arrow) with prominent intimal proliferation and very small residual lumen (asterisk).

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