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Institute of Veterinary, Animal & Biomedical Sciences BACHELOR OF VETERINARY SCIENCE BVSc 1 2012
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Institute of Veterinary, Animal & Biomedical Sciences
BACHELOR OF VETERINARY SCIENCE
BVSc 1
2012
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Contents
IVABS Teaching Calendar 2012 ............................................................................................ 1
Timetables ............................................................................................................................ 3
Paper Outlines ...................................................................................................................... 7
227.102 – Biochemistry for Veterinary Science ............................................................................ 9
227.103 – Veterinary Anatomy 1 .............................................................................................. 25
227.104 – Veterinary Physiology 1 ........................................................................................... 33
227.105 – Animal Behaviour, Welfare and Handling .................................................................. 43
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IMPORTANT
The information contained within is correct as at the date of printing. However, some details may be subject to change. Should any changes occur you will be
notified and updates will be place on the Stream Site: BVSc ZOO.
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1
IVABS Teaching Calendar 2012
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Timetables
Understanding Your Timetable
DAY
START TIME Paper Number Class Type1 Room2
Classes run for approximately 50 minutes unless otherwise stated.
NOTE: Timetables are subject to change. For the most up‐to‐date timetable, please refer to BVSc ZOO or you class Stream site.
1 Lecture, Laboratory, Tutorial, Practical. Note some lab classes will be streamed. This will be indicated by an ‘S’. See paper outline for more information. 2 These are also abbreviated. A key is at the bottom of each timetable page.
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Paper Outlines
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227.102 – Biochemistry for Veterinary Science
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Paper Number and Title: 227.102 ‐ Biochemistry for Veterinary Science Credits Value: 15 Semester: 2 Campus: Manawatu Mode: Internal Paper Coordinator:
Dr Mark Patchett (MLP), Institute of Molecular BioSciences, Science Tower B, room 3.35, phone (06) 356 9099 ext. 7516, email: [email protected].
Contributing Staff: A/Prof. Kathryn Stowell (KMS), Institute of Molecular BioSciences, Science Tower D, room 3.08, phone (06) 356 9099 ext. 7517, email: [email protected]. Dr Andrew Sutherland‐Smith (AJSS), Institute of Molecular BioSciences, Science Tower C, room 4.03b, phone (06) 356 9099 ext. 2578, email: A.J.Sutherland‐[email protected]. Robert Cleaver, Institute of Molecular BioSciences, Science Tower D, room 4.07, phone (06) 356 9099 ext. 2596, email: [email protected]. Dr Rose Motion, Institute of Molecular BioSciences, Science Tower C, room 3.18, phone (06) 356 9099 ext. 2582, email: [email protected].
Aim: This paper aims to provide an introduction to the major metabolic processes which animals use to synthesise cell constituents, to provide energy for work (such as muscle contraction) and to maintain a stable blood glucose concentration. Examples of the control of these processes, including hormonal control, are presented. In addition, the properties of enzymes and other proteins, such as haemoglobin, and some topics in membrane biochemistry are covered. All of these are relevant to subsequent areas in the veterinary curriculum, in Physiology, Pharmacology, Toxicology and Clinical Pathology in particular. The practical component aims to provide a brief introduction to biochemical techniques widely used in biological science, as well as emphasising numerical skills and quantitative accuracy which are important in the BVSc. programme.
Calendar Prescription: A study of cellular processes at the molecular level: Proteins, enzymes and membranes. Energy changes in chemical reactions. Description of the major processes of carbohydrate, lipid and amino acid metabolism. Integration and regulation of metabolism in animals. A laboratory course emphasising biochemical techniques of wide application.
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Learning Outcomes: A student who successfully completes this paper can:
1) Describe the main elements of protein structure, the relationship between protein structure and function, and the factors that affect the activity of enzymes.
2) Clearly detail major metabolic processes in animals, including the chemical changes which occur in carbohydrate, lipid and amino acid metabolism, the functions of the pathways and the intracellular control of the pathways.
3) Explain the biochemistry of aspects of biomembrane structure and function.
4) Discuss the roles of selected hormones in controlling metabolic pathways (including the mechanism of control), the roles of various organs, and the integration of major metabolic pathways.
5) Interpret/explain new data and answer questions by integrating and applying the knowledge and understanding outlined above in combination with knowledge and understanding gained in 123.101 Chemistry and Living Systems and 162.101 Biology of Cells, or similar papers.
6) Carry out biochemical analyses and separations, calculate the concentrations of biomolecules in solution, measure the rates of enzyme‐catalysed reactions and calculate the specific activity of an enzyme in solution.
7) Demonstrate an understanding of the experimental rationale and techniques used in each laboratory practical, the calculations used to process data obtained in these practicals, and prion/TSE biology.
Pre-requisites Selection into the BVSc programme. A basic knowledge of the structure, properties and reactions of organic compounds, and the concepts of chemical equilibrium and chemical kinetics (123.101). An understanding of cell structure and function, and the overall role of DNA, RNA and protein in the flow of information in cells (162.101). Familiarity with the use of items of laboratory equipment introduced in 123.101 and 162.101.
Assessment The lecture and the laboratory practical components are assessed separately. The lecture component is assessed by an 80 minute semester test (with questions set for 70 minutes) held on the first Wednesday evening after the mid‐semester break (20% of overall assessment), and a three‐hour final examination (60%). The practical component (20% of overall assessment) is assessed by an open book written (lab theory) test (8%) based on laboratory practicals and the tutorial on prions and TSEs, and an open book practical test (written instructions for this 12% test are handed out one week prior to the test) that is closely based on techniques you will have already used in the laboratory course. You must pass the practical component of the paper. To do well in the open book written (lab theory) test it is important that your Laboratory Manual contains a complete and accurate record of your experiments, subsequent data manipulation and calculations of results. It is also important that you understand the experimental rationale and techniques used in each practical,
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and have answered any associated problem sets and questions. Laboratory attendance is compulsory. Books will be checked for completeness and accuracy at the end of each practical. Early departure from a laboratory practical session without having completed the experiment AND the writing up will be recorded as an absence. Copies of the laboratory theory tests for the last two years are printed at the end of the 227.102 Laboratory Manual. Copies of the semester tests for the last two years are printed at the end of the 227.102 Course Material booklet. Both the Laboratory Manual and the Course Material booklet are available from the Student Notes Distribution Centre (SNDC, located in The Printery Building which is on the corner of University Avenue and Albany Drive). The Course Material ‘booklet’ may not be supplied bound, but please keep this material together and bring it to every lecture. You must collect the laboratory manual from SNDC and bring it to your first laboratory class; for Stream H Thursday 6–9 pm in week 2, for Stream V Friday 10 am – 1 pm in week 2. For the laboratory practical course, students must provide their own laboratory coats and safety glasses. Suitable footwear must be worn in the laboratory. Marked tests can be collected from the Institute of Molecular Biosciences (IMBS) secretarial office (ScB4.08). You will be notified in lectures or on Stream when these are ready for collection.
Assessment Test / Examination Date Time and Place Contribution to
final grade
Semester test Wednesday 12 September 7 ‐ 8.25 pmMarsden
20%
Written lab theory test(on Practicals 1 ‐ 5 AND the tutorial on prions and TSEs)
Thursday 27 September(for both lab streams)
6 – 7.20 pmMarsden 8%
Practical test Thursday 4 October (Stream H)Friday 5 October (Stream V)
6 – 9 pm in ScD4.0910 am – 1 pm in ScD4.09
12%
Final examination Thursday 8 November 2.15 ‐ 5.30 pm 60%
Final examination times may be subject to change – check this date and time before the start of
the semester 2 final examination period.
Alignment of Assessment to Learning Outcomes Assessment of student understanding of the course will be based on:
Assessment Description Learning Outcomes Assessed Contribution toPaper Mark
1. 2. 3. 4. 5. 6. 7.
Semester test 20 %
Final examination 60 %
Laboratory theory test 8 %
Laboratory practical test 12 %
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Requirements to Pass 227.102 Attend laboratory practicals 1 – 5. Attendance at these laboratory practicals is
compulsory. A record of attendance is taken. If absence is unavoidable then a medical certificate, or a satisfactory written explanation, must be given to the laboratory supervisor or paper coordinator. Unexplained non‐attendance at a laboratory practical will result in failure of the 227.102 paper. [If sufficient notice is given then it may be possible to arrange an alternative time to attend a particular laboratory practical, but this cannot be guaranteed.]
Obtain an aggregate mark of 50% or higher for the assessment related to the practical component, i.e. the Written Lab Theory Test and the Practical Test.
Obtain a mark of 40% or higher in the final examination.
OBTAIN AN AGGREGATE MARK OF ≥ 50% FOR THE PAPER.
Missed Tests, Aegrotat (AEG) consideration and Impaired Performance Please contact the paper coordinator as soon as possible after missing a test. If you are prevented by illness, injury or serious crisis from attending a test or examination, or if you consider that your performance has been seriously impaired by such circumstances, you may apply for an aegrotat or an impaired performance consideration. You must apply on the form available from the Examinations Office (NSATS), the Student Health Service or the Student Counselling Service. To be considered for an aegrotat pass on the final examination, your semester test performance should be well above the minimum pass standard, so that the examiners can be confident you would have passed the paper if you had completed the missing assessment. This advice is also relevant to Impaired Performance applications for the final examination.
Teaching Approach The paper is taught via lectures (three per week) and laboratory classes (one three‐hour class per week). Each week students are expected to spend additional time reading the textbook and preparing for lectures and practical classes. It is particularly important in this subject that the relevant sections of the textbook (as indicated in the lectures outlines) are studied by students in their own time to reinforce their understanding of the lecture material and as preparation for weekly tutorials. See also the study advice in the Course Material booklet.
Student Time Budget These time allocations are for a ‘typical’ student and should be used as a guide only. Formally scheduled learning Time (hours) Lectures, 3 per week (4 in week one, including intro 'lecture'), 12 weeks 37 Laboratory classes, ~3 hours per week, 6 weeks 18 Tutorials, 1 hour per week, 12 weeks (maximum) 12
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Non‐scheduled learning and preparation Preparation for laboratory sessions, 1.5 hours per week, 6 weeks 9 Consolidating laboratory learning, 1 hour per week, 6 weeks 6 Reading the text and other material to support and reinforce learning in lectures and tutorials, 4 hours per week, 12 weeks 48 Preparation for semester test, practical‐related tests and final examination 49 Assessment related Semester test 1.5 Practical test 3 Laboratory theory test 1 Final examination 3 Total 187.5
Learning Programme and Schedule Lectures/tutorials Monday (lecture) 10.00 ‐ 10.50 am WB1 Monday (tutorial*, weeks 2 ‐12) 2.00 ‐ 2.50 pm AH1 Tuesday (two lectures, week 1 only) 10.00 ‐ 10.50 am SSLB4, AND 1.00 ‐ 1.50 pm in SSLB5 Wednesday (lecture, week 1 only) 10.00 ‐ 10.50 am SSLB7 Thursday (lecture, weeks 2‐12) 9.00 ‐ 9.50 am SSLB4 Friday (lecture, weeks 2 ‐12) 9.00 ‐ 9.50 am AH2
*In week 4, the Monday 2 pm tutorial timeslot in AH1 will be used for a lecture. Laboratory classes begin in week 2. Stream H (Thursday lab) students attend the lab safety talk in week 1 at 6 pm on Monday 16 July, ScD4.09. Thursday 6.00 pm ‐ 9.00 pm (Stream H) ScD 4.09 Friday 10.00 am ‐ 1.00 pm (Stream V) ScD 4.09
Textbook and Other Recommended Reading Textbook of Biochemistry with Clinical Correlations, by TM Devlin (7th edition preferred; Massey University library call number 612.015 Tex), is the recommended textbook and should be your main reference apart from lecture notes and the 227.102 Course Material booklet available from the SNDC. A copy of the textbook is held in the library’s reserved book collection. Other good Biochemistry texts in the library include Biochemistry (6th edition, 2007) by J. Berg (Massey University library call number 572 Ber), Biochemistry and Molecular Biology (4th edition) by Elliott & Elliott (library call number 572 Ell), Biochemistry (2nd and 3rd editions) by D Voet and JG Voet, Fundamentals of Biochemistry (1999) by D Voet et al., and Biochemistry (3rd edition, 2005) by Champe et al. Other good general Biology texts in the library include: Biology ‐ Campbell et al.; Molecular Biology of the Cell ‐ Alberts et al.; Molecular Cell Biology ‐ Lodish et al.
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Feedback and Support for Student Learning Internal assessments will be marked and returned to students within three weeks of submission. Students with specific questions about topics covered in this paper are encouraged to contact staff by email and / or make appointments to see staff for advice and guidance. The paper coordinator can be contacted preferably by email ([email protected]), or by telephone (06 356 9099 extn. 7516).
Grievance Procedures A student who claims that he/she has sustained academic disadvantage as a result of the actions of a University staff member should use the University Grievance Procedures. Students, whenever practicable, should in the first instance approach the University staff member concerned. If the grievance is unresolved with the staff member concerned, the student should then contact the College of Sciences office on his/her campus for further information on the procedures, or read the procedures in the University Calendar.
Intellectual Honesty: Plagiarism Policy When students make direct use of, or quote, the work of others, they are required to acknowledge the source in every instance. Massey University, College of Sciences, has taken a firm stance on plagiarism and any form of cheating. Plagiarism is the copying or paraphrasing of another person’s work, whether published or unpublished, without clearly acknowledging it, e.g. by in‐line citations. It includes copying the work of other students. Plagiarism will be penalised; it is likely to lead to loss of marks for that item of assessment and may lead to an automatic failing grade for the paper and/or exclusion from reenrolment at the University.
Exemptions The paper coordinator will consider applications for full and 'laboratory‐only' exemptions from this paper. Applications for exemptions, and all necessary accompanying information, must be received by the paper coordinator in the first week of semester two AT THE LATEST. Typically full exemptions will be based on recent (within the last 4 years) passes (B or better) in an introductory Biochemistry paper, e.g. Massey University’s 122.102 Biochemistry of Cells, AND at least one higher‐level Biochemistry paper with substantial metabolic biochemistry content, e.g. Massey University’s 122.233 Metabolic Biochemistry. For example, an A– pass in 122.102 within the last five years and a B+ pass in 122.233 within the last four years would entitle a student to a full exemption from 227.102. Exemptions from the 227.102 laboratory practical component only will be considered provided that a prior mark for the practical component of 122.102 or equivalent introductory Biochemistry paper is at least 65%. If in doubt please provide the paper coordinator ([email protected]) with a copy of the relevant academic transcript(s) AND details of the relevant papers (the more detail the better) as soon as possible.
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Timetable
Week Date Lecturer # Topic Laboratory Course*
1 16/7 17/7 17/7 18/7 19‐20/7
MLP AJSS AJSS AJSS
1 2 3
Introduction to 227.102 (10 am, WB1) Proteins, amino acids (10 am SSLB4) Properties of proteins (1 pm SSLB5) Prot struct/function (Mb) (10 am SSLB7) VLE
Thurs stream students attend Lab Safety Talk, Mon 6 pm, ScD4.09. NO LABORATORY PRACTICALS
2 23/7 26/7 27/7
AJSS AJSS AJSS
4 5 6
Protein structure/function (Hb) Enzyme properties Enzyme kinetics
Practical 1: Properties of proteins & amino acids (RM) H Practical 1: Properties of proteins & amino acids (MLP) H
3 30/7 2/8 3/8
AJSS KMS KMS
7 8 9
Allosteric enzymes Introduction to Metabolism Introduction to Metabolism
Practical 2: Determining Albumin and Globulins (RM) H Practical 2: Determining Albumin and Globulins (MLP) V
4 6/8 9/8 10/8
KMS KMS KMS
10 11 12
Introduction to Metabolism Energy conversions (Bioenergetics) TCA cycle
No lecture at 10 am; today’s lecture is at 2 pm in AH1 Practical 3: Enzyme Activity of Chymotrypsin (RM) H Practical 3: Enzyme Activity of Chymotrypsin (MLP) V
5 13/8 16/8 17/8
KMS KMS KMS
13 14 15
TCA cycle. Introduction to e– transport. e– transport e– transport, oxidative phosphorylation
Tutorial on Prions & TSEs, 6 ‐ 7.15 pm in ScD1.03 (stream H) Tutorial on Prions & TSEs, 10 am or 11.30 am in AHB3.02C (stream V) Surnames A‐I, 10‐11.20 am; surnames J‐Z, 11.30 am‐12.50 pm
6 20/8 23/8 24/8
KMS KMS KMS
16 17 18
Carbohydrate metabolism Glycolysis Glycolysis
Practical 4: Yeast fermentation of glucose to ethanol (RM) H Practical 4: Yeast fermentation of glucose to ethanol (MLP) V
MID‐SEMESTER BREAK
*[ScD4.09]: Thursday, 6 – 9pm, Stream H Friday, 10am – 1pm, Stream V
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7 10/9
12/9 13/9 14/9
KMS KMS KMS
19 20 21
Gluconeogenesis Regulation of glycolysis/gluconeogenesis Glycogen breakdown and synthesis
Tutorial for the semester test (2 pm, AH1) SEMESTER TEST, 7 ‐ 8.25 pm, Marsden, 20% (MLP) Practical 5: Use of a Diagnostic Enzyme (MLP) Stream H Practical 5: Use of a Diagnostic Enzyme (MLP) Stream V
8 17/9 20/9 21/9
KMS MLP MLP
22 23 24
Control of glycogen metabolism Triacylglycerols/fatty acids Transport and oxidation of fat
NO LABORATORY PRACTICAL ‘Tutorial’, in ScD4.09, for the Laboratory Theory Test.
9 24/9 27/9 28/9
MLP MLP MLP
25 26 27
Ketone bodies, fatty acid synthesis Fatty acid synthesis continued TAG synthesis, control of FA metabolism
LAB THEORY TEST, 6 – 7.20 pm, Marsden, 8% (MLP) HV Laboratory Practical Test handed out. NO LABORATORY PRACTICAL
10 1/10 4/10 5/10
MLP MLP MLP
28 29 30
Protein, amino acid metabolism Vit B12 and folate. Purine synthesis. Amino acid synthesis & transport
PRACTICAL TEST 6 ‐ 9 pm, ScD4.09, 12% (RM) H PRACTICAL TEST 10 am ‐ 1 pm, ScD4.09, 12% (MLP) V
11 8/10 11/10 12/10
MLP MLP MLP
31 32 33
Fluid mosaic model, membrane proteins. PGHS and prostaglandins Receptors & signal transduction
NO LABORATORY PRACTICAL NO LABORATORY PRACTICAL
12 15/10 18/10 19/10
MLP MLP MLP
34 35 36
Membrane transport Integration of metabolism Integration of metabolism
NO LABORATORY PRACTICAL NO LABORATORY PRACTICAL
13 22/10 5/11
Study Week begins
10 am – 12 noon, tutorial on lectures 1‐36 in ScC2.11
14 8/11 PLEASE CHECK DATE & TIME FINAL EXAM, Thursday 2.15 ‐ 5.30 pm, 60%
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Lecture Outline The first ‘lecture’ is used to introduce the 227.102 paper, particularly the concept of metabolism and its relevance to veterinary practice, and to go through the paper outline document, Course Material booklet and Laboratory Manual.
1. Proteins and Enzymes
7 LecturesDr A. J. Sutherland‐Smith
Lectures 1‐2 Introduction to proteins a) Acid/bases in biology (revision) (Dev. p4‐11).
b) Properties of amino acids. (Dev. p75‐89).
c) Primary, secondary, tertiary and quaternary structure of proteins. (Dev.
p90‐98).
d) Interactions involved in secondary and tertiary structure. Protein stability,
folding, and denaturation (Dev. p116‐20). Lectures 3‐4 Protein structure‐function relationships
a) Globular proteins: Myoglobin and hemoglobin structure and function. Mechanisms and regulation of oxygen binding and consequences of co‐
operativity (Dev. p353‐366).
b) Fibrous protein: Collagen (Dev. p103‐106, 243‐247).
Lectures 5‐7 Enzymes
a) Introduction to enzymes (Dev. p377‐395).
b) Enzyme kinetics: Rates of reaction. Michaelis‐Menten theory and
application. (Dev. p400‐405).
c) Competitive and non‐competitive inhibition. Regulation of enzyme
activity. Kinetics analysis (Dev. p407‐413).
d) Regulation of enzyme activity, allosteric enzymes and effectors. Clinical
applications (Dev. p413‐421).
2. Introduction to Metabolism / Carbohydrate Metabolism
15 LecturesA/Prof. K.M.Stowell
Lectures 1‐3 Introduction to Metabolism
1. Why is energy required and where does it come from? ‐ concept of pathways ‐ anabolism and catabolism ‐ energy from foods ‐ energy transactions ‐ oxidation/reduction reactions ‐ transfer of reducing equivalents, cofactors and coenzymes ‐ ATP, the energy currency of the cell
2. What are energy‐rich compounds and how can they be used to provide
energy? ‐ introduction to thermodynamics ‐ relevance to carbohydrate metabolism ‐ chemotrophs and phototrophs
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‐ metabolic pathways link exergonic and endergonic reactions ‐ contribution of carbohydrates, lipids and protein to energy production
3. Acetyl CoA: the major source of fuel in animals
‐ what is it, where does it come from and what is it used for? ‐ pyruvate, an intermediate at the crossroads of metabolism ‐ pyruvate dehydrogenase reaction and control ‐ pyruvate dehydrogenase deficiency
Energy and Carbohydrate Metabolism Lectures 4‐5A. The Tricarboxylic Acid Cycle: the first step in energy conversion
4. What happens to acetyl CoA and how is it used to provide energy? ‐ overview of TCA cycle ‐ entry of acetyl CoA into the cycle ‐ important reactions of the cycle
5. What else are intermediates of the cycle used for?
‐ links to other metabolic pathways ‐ replenishment of intermediates removed ‐ regulation of the cycle
Lectures 6‐9B.
The Mitochondrial Electron Transport Chain: continuing the process of energy conversion
6. Overview of electron transport ‐ the mitochondrion: an intra cellular power house ‐ overview of oxidative phosphorylation: energy transduction ‐ overview of the electron transport chain ‐ oxidation‐reduction reactions and oxidation‐reduction potential ‐ free energy changes in redox reactions ‐ overview of mitochondrial electron transport chain carriers
7. Complexes in the mitochondrial electron transport chain
‐ NADH‐ubiquinone oxidoreductase (Complex I) ‐ FeS centers ‐ Succinate‐Ubiquinone oxidoreductase (Complex II) ‐ Ubiquinol‐cytochromec reductase (Complex III) ‐ cytochromes ‐ Q cycle ‐ Cytochrome c oxidase (complex four) ‐ inhibitors of the electron transport chain
8. Oxidative Phosphorylation
‐ the electrochemical gradient ‐ coupling ATP synthesis and electron transport ‐ P/O ratios ‐ inhibitors and uncouplers ‐ ATP synthase and mechanism of ATP synthesis
9. Mitochondrial substrate transport systems
‐ transport of adenine nucleotides and phosphate ‐ substrate shuttles to transport reducing equivalents ‐ getting acetyl CoA into the mitochondrion
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‐ mitochondrial calcium transporter ‐ uncoupling proteins: coping with cold Reactive oxygen species: the good and the bad ‐ damage and cellular defense ‐ NADPH oxidase ‐ cardiac disease
Lectures 10‐15C. Carbohydrate metabolism
10. Glycolysis I ‐ obtaining glucose from food ‐ glucose as an energy source ‐ what happens to glucose in different organs? ‐ the glycolytic pathway: investment and payback
11. Glycolysis II
‐ anaerobic glycolysis ‐ reoxidation of NADH to NAD+
‐ substrate shuttles ‐ aerobic glycolysis
12. Regulation of Glycolysis
‐ inhibitors of glycolysis ‐ hexokinase and glucokinase ‐ phosphofructokinase ‐ FBPase in liver and in heart ‐ control by covalent modification ‐ hormonal control ‐ pyruvate kinase
13. Gluconeogenesis
‐ Cori and alanine cycles ‐ glucose synthesis from lactate ‐ glucose synthesis from other substrates
14. Control of gluconeogenesis
‐ allosteric regulation of gluconeogenic enzymes ‐ hormonal control
15. Glycogen synthesis and breakdown
‐ why store glucose as glycogen? ‐ glycogenesis ‐ glycogenolysis ‐ regulation of glycogen synthesis and breakdown ‐ glycogen phosphorylase
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3. Lipid & Amino Acid Metabolism 8 Lectures
Dr M. L. Patchett
Lecture 1‐5: Devlin chap17, chap 18.3 & 18.5 Lecture 1 Triacylglycerols. Structure . Function as energy reserves.
Nomenclature of free fatty acids (FFAs). Palmitic, stearic, oleic acids; �‐6 and �‐3 fatty acids. Fat and the diet. Pancreatic lipase, digestion and absorption of fats. Micelles. Transport of triacylglycerols. Lipoproteins: Chylomicrons, VLDL. Lipoprotein lipase.
Lecture 2 Mobilisation of fat in adipose tissue. Hormone‐sensitive lipase and other lipases. Transport in the blood. Fatty acids bind to albumin. Delivery to mitochondria. Fatty acid activation by thioesterification to coenzyme A. Transport across the mitochondrial membrane. Role of carnitine. Fatty acid oxidation pathway. Outline of the pathway. Fate of acetyl CoA. Energy yield from palmitate oxidation
Lecture 3 Odd‐numbered carbon chain fatty acid oxidation. Counting carbon atoms into and out of the citric acid cycle. Implications for gluconeogenesis and nutrition. Ketone bodies. Synthesis, degradation, transport. Role in starvation and in diabetes. Fuel movements after fasting or starvation. Provision of fuel for the brain. Fatty acid synthesis. Cytosolic location and distinctions from oxidation pathway. Acetyl CoA carboxylase. Role of biotin cofactor. Acyl carrier protein (ACP). Fatty acid synthase; a multifunctional protein.
Lecture 4 FA synthesis (cont’d). Palmitate synthesis. Sources of acetyl CoA. Pyruvate from carbohydrate or protein. Transfer of acetyl CoA from mitochondria to cytosol. Transport via citrate. Acetyl CoA from acetic acid in ruminants. Sources of cytosolic NADPH. Malic enzyme (NADP malate dehydrogenase). Pentose phosphate pathway (no detail). Elongation, desaturation. Essential fatty acids & arachidonate.
Lecture 5 Triacylglycerol formation. Four reaction steps. Origin of glycerol phosphate. Nonhormonal control of fatty acid metabolism. Local controls by allosteric interactions. Rationale for this control. Acetyl CoA carboxylase. Activation by citrate. Inhibition by palmityl CoA. Malonyl CoA inhibits carnitine acyl transferase I.
Lectures 6‐8: Devlin chap 19.1‐19.5 & miscellaneous pages Lecture 6 Protein and Amino Acid metabolism.
Amino acids from proteins as a source of energy for immediate use or for storage as carbohydrate or fat. Nitrogen balance of the body. Removal of nitrogen: Oxidative deamination of glutamate – central role of glutamate dehydrogenase. Transamination of alanine and aspartate. Transdeamination. Glucogenic and ketogenic amino acids. Catabolism of glutamine, glutamate, aspartate and alanine: Conversion to
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PEP, glucose, acetyl CoA.
Lecture 7 Amino acid metabolism. Catabolism of isoleucine and the role of vitamin B12 in propionate metabolism. Water soluble vitamins. Vitamin B12 & folate nutrition: pernicious anemia, megaloblastic anemia and the methyl trap hypothesis, bush sickness (ruminants) [details provided in lectures and course material.] Purine biosynthesis. The purine ring is assembled from amino acids and folate derivatives.
Lecture 8 Amino group ‘transport’. Role of alanine, glutamine. Entry into urea cycle. Urea cycle reactions. (“You’re here because urea”)– overview only. Amino acid synthesis. Transamination and glutamine synthetase. Essential amino acids.
4. Membrane Biochemistry
4 LecturesDr M. L. Patchett
Lectures 1‐2: Devlin chap 12 & misc pages Lecture 1 Membranes – introduction. Amphipathic membrane lipids, micelles,
liposomes, bilayer formation & the entropy‐driven hydrophobic effect. Fluid mosaic model: description & experimental verification. Physiological importance & maintenance of membrane fluidity. Membrane proteins in metabolism, membrane transport, energy & signal transduction. Peripheral & integral proteins.
Lecture 2 Bitopic (glycophorin) & polytopic (bacteriorhodopsin) integral membrane proteins. Bilayer constraints on transmembrane segment(s) of integral proteins. Structure & function of prostaglandin H synthase (PGHS), a monotopic integral membrane protein. Eicosanoid (local) hormones: prostaglandins & thromboxanes. Control of eicosanoid levels for medical benefits: aspirin, Celebrex/Vioxx, rimadyl, misoprostol.
Lecture 3: Devlin chap 13 Lecture 3 Cell signaling receptors & signal transduction pathways (STPs). Intro.
Membrane receptor‐mediated signaling systems. G‐protein‐coupled receptors: examples of glucagon/lipolysis and photons/vision. Summary of signal transduction processess.
Lecture 4: Devlin chap 12, sections 12.6–10 (selective coverage) & misc pages Lecture 4 Classification & properties of membrane transport systems, according to
passive, active, uniport & co‐transport (symport or antiport). Transepithelial glucose transport, including distinction between and localisation of Na+/glucose symporter (SGLT) and the GLUT glucose transporters (more later), & biochemical basis of glucose/saline rehydration therapy. Cardiac glycosides & the biochemical basis for digitalis treatment of congestive heart failure.
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5. Integration of Metabolism and Hormonal Regulation of Glucose Homeostasis
2 LecturesDr M. L. Patchett
Devlin chap 21 (highly selective coverage)
Integration of metabolism. Introduction. Feeding, fasting, starvation and exercise. Integration of metabolism. Carbohydrate, lipid and amino acid metabolism in major organs. Liver. Muscle. Adipose tissue. Brain. Summary of transport of metabolites between organs. Regulation of glucose homeostasis. Regulation of glucose supply by allosteric and hormonal control of carbohydrate and lipid metabolism.
Role of ketone bodies and amino acids in prolonged fasting and starvation
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227.103 – Veterinary Anatomy 1
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Paper Number & Title: 227.103 ‐ Veterinary Anatomy I Credits: 15 Semester: 2 Campus: Manawatu Mode: Internal Paper Coordinator
Prof. Peter Davie, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 6.20, phone (06) 356 9099 extn. 7447, fax (06) 350 5636, email [email protected].
Other Contributing Staff Assoc Prof. Christine Thomson, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 6.09, phone (06) 356 9099 extn 7769, fax (06) 350 5714, email [email protected]. Dr Kavitha Kongara, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 6.07, phone (06) 356 9099 extn 5363, fax (06) 350 5714, email [email protected]. Dr Preet Singh, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 6.04, phone (06) 356 9099 extn 7893, fax (06) 350 5714, email [email protected].
Aim To provide veterinary undergraduate students with the anatomical basis for understanding locomotion and exercise in vertebrate animals, including blood circulation and respiration.
Calendar Prescription The anatomy of the locomotor and cardiopulmonary systems are studied by dissection of the dog, isolated bones and radiographic images. Regions studied include limbs, vertebral column and thorax. Anatomical examination of live mammals, when available, compliments dissection. Early embryology from fertilization to formation of a tubular embryo is studied followed by development of musculoskeletal, cardiovascular and respiratory systems. Aspects of the mechanics of the locomotor system are discussed. Integration of heart and lungs with the locomotor system is studied.
Intended Learning Outcomes After successful completion of 227.103 Veterinary Anatomy I students should be able to:
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1. Identify gross anatomical structures of the forelimbs and hindlimbs and axial neck, thorax and lumbar regions and the thoracic contents of mammals as seen in dogs and cats.
2. Explain how the arrangements of muscles and nerves, bones and joints permit and restrict
movement especially in locomotion. 3. Discuss the anatomical basis of functioning of the heart and lungs. 4. Describe the development of musculoskeletal structures, cardiovascular and respiratory
systems from fertilization to fetus. 5. Explain the principles of radiographic imaging including x‐rays and CT. 6. Discuss integrated functioning of musculoskeletal, respiratory and cardiovascular systems
in locomotion.
Pre- and Co-requisites 227.103 Veterinary Anatomy I is only available to BVScI students and is compulsory for those students. The pre‐requisite is completion of the BVSc 1 Semester 1 papers, and/or admission to the professional phase of the BVSc programme. This paper is designed to integrate with Veterinary Physiology I (227.104) and Biochemistry for Veterinary Science (227.102). This paper is designed to lead toward Veterinary Anatomy 2 (227.203) Themes occurring in this paper include musculoskeletal structure and functioning, locomotion, respiration and imaging.
Assessment Assessment Due Date / Deadline
On‐line assessment, Applied Anatomy
7 August.
Practical assessments (3) During semester (14 August and 25 September). End of semester (17 October).
Dissection based assignment 19 September. Assignment will not be marked if submitted after closing date and time, unless there is satisfactory reason given.
Final written exam 31 October
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Alignment of Assessment to Learning outcomes Assessment Description Learning Outcomes Assessed Contribution to Paper
Mark
1 2 3 4 5 6
On‐line assessment 0%
Practical assessment 1&2 10% each
Practical assessment 3 20%
Dissection based assignment 10%
Final written exam 50%
NOTE: The pass mark for anatomy practical tests is 60%. The practical tests are designed to assess the student's knowledge of gross anatomy. The final examination will cover all the material presented in the lectures and practical classes. Pass mark for the written exam is 50%. Students must pass both the practical and written assessments to pass the paper.
Student Time Budget Lectures 38 Practical classes 33 Practical tests 3 Assignment 5 Computer aided learning 15 Study & revision 95 TOTAL 189 hours
Requirements to Successfully Complete the Paper Attendance at all practical classes, contributory tests and exams is compulsory. Failure to attend a practical class requires an explanation to the paper coordinator. A pass in at least one practical test is required for successful completion of the course work of the paper.
Deadlines and Penalties The assignment is to be handed in on or before the deadline. Failure to meet the deadline may result in the assignment not being marked or downgrading of the mark. Students are required to sit tests and the final examination at the scheduled times. If a student does not sit them at these times, and does not have a valid reason, they will be given no marks for those sections which were missed.
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Conditions for Aegrotat Pass and Impaired Performance If a student is prevented by illness, injury or serious crisis from attending an examination or test, or if a student considers that his/her performance has been seriously impaired by those circumstances, then he or she may apply for aegrotat or impaired performance consideration. Applications must be on the form available from the Examinations Office, the Student Health Service, or the Student Counselling Service. To qualify for an aegrotat pass on your final examination your performance in other elements of assessment must be clearly above the minimum pass standard.
Proposed Feedback and Support for Student Learning Academic staff contributing to 227.103 will endeavour to help students understanding of the sections of this paper for which they have responsibility. Students who fail the first contributory test will be advised to seek an interview with the paper coordinator to assess their learning strategies. If appropriate, additional tuition through the College of Sciences first year student assistance scheme may be arranged by the paper coordinator.
Textbook(s) and Other Recommended Reading Laboratory study guides will be provided for this paper. The text required for this paper is: Dyce, K.M., Sack, W.O. and Wensing, C.J.G. 2002. Textbook of Veterinary Anatomy. 4th Edn W B
Saunders and Co.
Additional Costs Students are expected to have lab coats and proper footwear for the laboratories (see Laboratory safety below). Each dissection group will need a basic dissection kit as for example is used in biology papers. See the BVSc Programme Guide for more details on where to purchase these from. Boxes of selected dog bones are available on condition that if lost or damaged the student will pay $100. No money is required at the time of issue. No other additional costs are anticipated. Additional dissecting instruments will be offered for purchase, whilst advised, they are not essential.
Additional Information and Advice Students in Veterinary Anatomy papers should feel free to use the computers in the Anatomy Museum Room 2.10 when there are no classes in session in the Museum. The usual rules for use of this learning space apply.
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Laboratory Safety It is a requirement that safe laboratory practices be adopted at all times. Sensible behaviour is essential, while clean laboratory coats and solid footwear must be worn. Because of the danger from broken glassware, chemical spills and sharp instruments, open footwear such as sandals and jandals are not acceptable. For public health reasons, eating and drinking in the Anatomy Laboratory and Museum are forbidden. For similar reasons, no biological material may be removed from any laboratory. Specific potential hazards (and how to avoid them), associated with the performance of individual practical classes, are listed where appropriate. Please observe these precautions. In the event of an accident, it must be reported to the academic staff member supervising your class. An "Incident Report" must be completed, signed and filed with the Institute of Veterinary, Animal & Biomedical Sciences Safety Officer Peter Wildbore in Room 5.04.
This paper contributes to the following professional knowledge, skills and attitudes:
Literacy, numeracy and communications skills required of a professional.
Abilities in critical scientific observation, data collection and accuracy.
Scientific thinking and analysis.
Biological variation in structure within a species.
Three dimensional structures and topographical concepts.
Handling animal tissues
Grievance Procedures A student who claims that he/she has sustained academic disadvantage as a result of the actions of a University staff member should use the University Grievance Procedures. Students, whenever practicable, should in the first instance approach the University staff member concerned. If the grievance is unresolved with the staff member concerned, the student should then contact the College of Sciences office on his/her campus for further information on the procedures, or read the procedures in the University Calendar.
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227.104 – Veterinary Physiology 1
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Paper Number & Title: 227.104 ‐ Veterinary Physiology 1
Credit Value: 15 Semester: 2
Campus: Manawatu Mode: Internal
Paper Coordinator Dr Gordon W Reynolds, Institute of Food, Nutrition and Human Health, Riddet Building, room 2.17, phone (06) 356 9099 extn 81426, fax (06) 350 5671, email: [email protected].
Other Contributing Staff Dr Preet Singh, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 6.04, phone (06) 356 9099 extn 7893, fax (06) 350 5714, email: [email protected]. Assoc Prof. John Cockrem, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 6.07, phone (06) 350 4483, fax (06) 350 5714, email: [email protected]. Dr David Simcock Institute of Food, Nutrition and Human Health, Riddet Building, room 2.59, phone (06) 356 9099 extn 81565, fax (06) 350 5671, email: [email protected]. Prof. Peter Davie, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower room 6.14, phone (06) 350 69099 extn 7447 fax (06) 350 5714 email: [email protected].
Aims After successful completion of 227.104 Veterinary Physiology I students should: 1) Have a sound knowledge and understanding of the basic physiology and microstructure of
excitable tissues, including nerves and muscles, and the cardiovascular system, respiratory system and endocrine system of mammals.
2) Be able to combine the knowledge gained with that from other papers in anatomy,
biochemistry and physiology to provide the scientific understanding required for them to successfully undertake the paraclinical and clinical components of the BVSc programme.
Calendar Prescription Lectures will cover the physiology of excitable tissues, plus functions and controls within the cardiovascular, respiratory and endocrine systems, in animal species of veterinary importance. A practical and histology programme supporting the lecture content.
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Learning Outcomes A student who has completed 227.104 should have a good understanding of: 1) The basic functions of nerves and the organisation of the mammalian nervous system. 2) The physiology of muscle contraction. 3) The electrical and mechanical activities of the heart. 4) The physiological mechanisms controlling blood circulation and blood pressure. 5) Lung ventilation and the reflex control of respiration. 6) Oxygen and carbon dioxide transport in the blood and lung gas exchanges. 7) The functions of blood buffers. 8) The major endocrine organs of the body. 9) The regulation of blood glucose levels. 10) The actions of growth hormone, thyroid hormones and adrenal hormones.
Pre- and Co-requisites 227.104 Veterinary Physiology I is only available to BVSc I students and is compulsory for those students. The pre‐requisite is completion of the semester one selection papers, or equivalent, and admission to the professional phase of the BVSc programme.
Assessment Assessment will comprise two contributory 1‐hour combined lecture/practical written tests in weeks 5 and 10, and a 3‐hour final examination.
Alignment of Assessment to Learning Outcomes Assessment Description Learning Outcomes Assessed Contribution
to Paper Mark
1 2 3 4 5 6 7 8 9 10
Written test: Excitable tissues
20%
Written test: Endocrine & cardiovascular systems
20%
Final written exam 60%
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Learning Programme and Schedule The major topics of this paper, with the name of the academic in charge given in brackets, are: Excitable tissues (Dr Gordon Reynolds). Cardiovascular physiology (Prof Peter Davie). Respiration (Dr David Simcock). Endocrinology (Assoc Prof John Cockrem). Histology (Dr Cameron Knight). Excitable Tissues ‐ (12 lectures and 4 practical sessions). This section serves to instruct students on how the electrical properties of tissues arise and how those properties contribute to the functions of muscle and neural tissues. Subjects covered include body fluids, membrane potentials, conduction of action potentials, contraction of skeletal, smooth and cardiac muscles, neuromuscular junctions and organisation of mammalian nervous system. Cardiovascular ‐ (9 lectures and 3 practical sessions). In this section students are taught the microstructure of the cardiovascular system, the physiology of the heart including ECG’s, blood vessel structure and function, blood flow and cardiovascular reflexes. Applied aspects of exercise, gravity and haemorrhage are also considered. Respiration ‐ (7 lectures and 2 practical sessions). In this section students learn about lung mechanics and ventilation, gas exchange and lung perfusion, gas transport, blood buffers, reflexes controlling breathing and the defence mechanisms protecting the respiratory tract. Endocrinology ‐ (7 lectures and 1 practical session). In this section the students are taught the major endocrine tissues of mammals, the principles of hormone secretion and action, the regulation of blood glucose, thyroid hormones and adrenal hormones. NOTE: During teaching of each of the above sections, examples with clinical importance are used to reinforce the physiological principles taught and to emphasise the relevance to clinical practice of understanding how normal animals function.
Timetable Lectures Monday 9am SSLB3 Tuesday 9am AH2 Wednesday 9am AH2 Practical Thursday 10am Vet4.02/AHC4
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Student Time Budget The total should be 187.5 hours, i.e. 15 weeks at 12.5 hours per week. It includes time in preparing for all types of assessment, formally‐timetabled time, and time scheduled by the student him / herself. The formally timetabled time should rarely be more than 50% of the total time, and for more advanced papers it may be a small fraction. Lectures 36 Practical classes 36 Contributory tests 2 Revision 30 Study 83.5 TOTAL 187.5
Requirements to Successfully Complete the Paper Attendance at practical classes is compulsory. In addition, to complete this paper students must sit the lecture / practical tests, and also sit the final exam, unless they have a valid reason for not doing so (see also aegrotat pass / impaired performance conditions below).
Deadlines and Penalties The only deadline which will apply in this paper is the requirement that tests and the final examination are sat at the timetabled times. If a student does not sit them at these times, and does not have a valid excuse, they will be given no marks for those sections which were missed.
Conditions for Aegrotat Pass and Impaired Performance If you are prevented by illness, injury or serious crisis from attending an examination or test, or if you consider that your performance has been seriously impaired by those circumstances, you may apply for aegrotat or impaired performance consideration. You must apply on the form available from the Examinations Office, the Student Health Service, or the Student Counselling Service. To qualify for an aegrotat pass on your final examination your performance in other elements of assessment must be clearly above the minimum pass standard.
Proposed Feedback and Support for Student Learning Academic staff contributing to 227.104 will endeavor to help students understanding of the sections of this paper for which they have responsibility. For this purpose they can often be contacted in their offices, or by phone or email. If you wish to speak to them in their office, it is a good idea to make an appointment for this purpose. If a number of students have problems with the same part of the paper, staff will generally agree to a group discussion to rectify the matter.
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Textbook(s) and Other Recommended Reading There is no set text for this paper. Comprehensive study guides will be provided for each section of the paper. If students wish also to purchase an appropriate physiology textbook the following is recommended: Sjaastad O.V., Sand, O. and Hove, K. Physiology of Domestic Animals. 2nd Edition. Oslo:
Scandinavian Veterinary Press. An alternative is Guyton and Hall’s "Textbook of Medical Physiology", but it contains no veterinary material. Study notes will also be provided for the histology component of 227.104; there is no set textbook. Students wanting to purchase a histology book, the following are recommended: Histology: A Text and Atlas by Michael H Ross, Lynn J Romrell and Gordon I Kaye, 3rd edition,
Williams & Wilkins; Applied Veterinary Histology by William J Banks, 2nd edition, Williams & Wilkins). As a recommended reference, there are several copies of Applied Veterinary Histology by William J Banks, 2nd edition, Williams & Wilkins available in the library reserve book room.
Additional Costs No other additional costs are anticipated.
Additional Information and Advice Students in Veterinary Physiology papers should feel free to use the computers in Laboratory 5.01, when there are no classes in session in that lab. The usual rules for use of laboratories will apply.
227.104 Practical Course Aims The major aim of these practicals is to provide reinforcement of physiological concepts introduced in lectures. This reinforcement will be extended when writing up practical reports in which it is necessary to relate class observations to theoretical considerations. In addition students will develop such practical skills as basic tissue dissection techniques and use of a variety of physiological instrumentations. Finally, animals vary in their responses to stimuli; inevitably such "biological variation" will be observed in practical exercises. An appreciation of the extent of this variation should be carried forward, particularly to later studies in para‐clinical and clinical studies. Requirements for histology practical classes Histology practical classes are designed to give the structural basis for physiological events and to provide a link between the concurrent study of anatomy and physiology. Knowledge of histology also serves as a valuable foundation for a number of subjects that are introduced later in the BVSc curriculum, e.g. histopathology, immunology and reproduction. Wherever possible the histology classes are integrated with the study of anatomy and physiology. To gain the maximum value from the histology practicals it is strongly advised that students read
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the relevant sections of the prescribed text and study guide prior to attending the laboratory class. Attendance at histology practical classes is compulsory. Requirements for physiology practical classes Practical classes are compulsory; an academic staff member must approve any unavoidable absences, before, or as soon as possible after the event. Failure to attend practical classes may result in failure in this paper. Proper respect for animals and animal materials, dead or alive, must be maintained at all times. This is a requirement of the Massey University Animal Ethics Code. A copy of this code is inserted in the front of the practical manual. Students should read this code and be prepared to abide by it if they are going to pursue studies in 227.104. All laboratory experiments involving animals are approved by the Massey University Animal Ethics Committee before being included in practical classes. Refer also to the section in your practical manual on “Ethical Guidelines for Students in Laboratory Classes Involving the use of Animals or Animal Tissues”, issued by the Australian and New Zealand Council for the Care of Animals in Research and Teaching, are reproduced. These guidelines must be adhered to at all times. In other experiments students are the experimental subjects. Notes covering the Massey University code of ethical conduct for research and teaching involving human subjects are also printed in the practical manual. Please read these notes and the Massey University Human Ethics Code, which is on the notice board in the physiology laboratory. At the end of each class, students are required to leave their section of the laboratory clean and tidy. This includes cleaning any glassware, instruments etc., which they have used, and ensuring that the floor, tables and benches are clean. Laboratory Safety It is a requirement that safe laboratory practices be adopted at all times. Sensible behaviour is essential, while clean laboratory coats and solid footwear must be worn. Because of the danger from broken glassware, chemical spills and sharp instruments, open footwear such as sandals and jandals are not acceptable. For public health reasons, eating, drinking and smoking in the laboratory are forbidden. For similar reasons, no biological material may be removed from the laboratory. Take particular care when handling chemicals, and in particular never mouth pipette liquid chemicals, solutions or drugs. Specific potential hazards (and how to avoid them), associated with the performance of individual practical classes, are listed where appropriate. Please observe these precautions. The histology teaching laboratory is equipped with high quality microscopes and slide sets. It is expected that this valuable resource will be treated with professionalism and respect. Any damage or deficiency must be reported immediately to a staff member. In the event of an accident, it must be reported to the academic staff member supervising your class. An "Incident Report" must be completed, signed and filed with the Health and Safety Officer, Peter Wildbore.
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Grievance Procedures A student who claims that he / she has sustained academic disadvantage as a result of the actions of a University staff member should use the University Grievance Procedures. Students, whenever practicable, should in the first instance approach the University staff member concerned. If the grievance is unresolved with the staff member concerned, the student should then contact the College of Sciences office on his / her campus for further information on the procedures, or read the procedures in the University Calendar.
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227.105 – Animal Behaviour, Welfare and Handling
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Paper Number and Title: 227.105 ‐ Animal Behaviour, Welfare and Handling Credits value: 15 Semester: 2 Campus: Manawatu Mode: Internal Paper Coordinator
Professor Kevin Stafford, Institute of Veterinary, Animal and Biomedical Sciences, Vet Tower, room 3.04, phone (06) 356 9099 extn 5546, fax (06) 350 5699, email [email protected].
Other Contributing Staff David Mellor, Institute of Food, Nutrition and Human Heath, phone (06) 356 9099 extn 81437, email [email protected].
Calendar Prescription The principles of veterinary ethology and their application to domestication, husbandry and production of domestic animals and veterinary science. An introduction to the principles of animal welfare. The principles and practices of safe animal handling and restraint. The diagnosis, treatment and prevention of animal behaviour problems.
Pre- and Co-requisites None.
Restrictions None.
Aim To help students develop an understanding of animal behaviour and an ability to observe behaviour accurately. To help students recognise what is normal and abnormal behaviour, a skill required for the clinical diagnosis of disease, the monitoring of convalescence, the treatment of behavioural problems of companion animals and the recognition of behaviours indicative of poor welfare in companion, farm and zoo animals. To help students understand the concepts of animal welfare, animal welfare science and animal rights. To teach students safe and effective handling and restraint of animals.
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Learning Outcomes On successful completion a student will be able to: 1) Recognize normal and abnormal animal behaviour. 2) Diagnose and treat behaviour problems in dogs and cats and the aetiology of these
problems. 3) Understand the concepts of animal welfare. 4) Understand learning and training. 5) Handle animals safely.
Assessment Animal handling examination 10% One Assignment 20% Mid semester test 20% Final Examination 50% Students must pass the horse handling mastery examination before they will be allowed to participate in equine clinical examination exercises in year three. The mastery test will comprise an examination of handling ability plus a short written test.
Alignment of Assessment to Learning outcomes Assessment Description Learning Outcomes Assessed Contribution to Paper
Mark
1. 2. 3. 4. 5.
Assignment 20%
Test 20%
Handling test 10%
Exam 50%
Deadlines and Penalties Assessment Due Date / Deadline Penalty
Assignment By 31st October 2012 None
Exam 7 November (pm)
Requirements to Successfully Complete the Paper Animal handling labs are compulsory.
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Learning Programme and Schedule Staff can vary between years in handling practicals. Kevin Stafford delivers 38 lectures, David Mellor delivers 10.
Student Time Budget Lectures 48 Lecture study time 38 Handling practicals 21 Test 1 Pre test study 10 Exam 2 Assigment time 48 Case discussion 5 Pre exam study 14 TOTAL 187 hours Timetable Monday, Tuesday, Wednesday and Friday lectures 8‐9am. Animal Handling practicals Friday 2‐5pm.
Proposed Feedback and Support for Student Learning Staff are available to discuss issues with students at an agreed time.
Textbook and Other Recommended Reading None.
Additional Costs None.
Conditions for Aegrotat Pass and Impaired Performance If you are prevented by illness, injury or serious crisis from attending an examination (or completing an element of assessment by the due date), or if you consider that your performance has been seriously impaired by such circumstances, you may apply for aegrotat or impaired performance consideration. You must apply on the form available from the Examinations Office, the Student Health Service or the Student Counselling Service. To qualify for an aegrotat pass on the final examination, you must have attempted at least 40% of the total formal assessment and your performance must be well above the minimum pass standard, so that the examiners can be confident that you would have passed the paper if you had completed the final examination. You may also apply for aegrotat consideration for other
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compulsory assessment elements (such as Semester Tests) that occur at a fixed time and place if you are prevented by illness, injury or a serious crisis from attending.
Plagiarism Massey University, College of Sciences, has taken a firm stance on plagiarism and any form of cheating. Plagiarism is the copying or paraphrasing of another person’s work, whether published or unpublished, without clearly acknowledging it. It includes copying the work of other students. Plagiarism will be penalized; it is likely to lead to loss of marks for that item of assessment and may lead to an automatic failing grade for the paper and/or exclusion from reenrolment at the University.
Grievance Procedures A student who claims that he/she has sustained academic disadvantage as a result of the actions of a University staff member should use the University Grievance Procedures. Students, whenever practicable, should in the first instance approach the University staff member concerned. If the grievance is unresolved with the staff member concerned, the student should then contact the College of Sciences office on his/her campus for further information on the procedures, or read the procedures in the University Calendar.
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