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C1 Mod 2 – Introduction to Psychoactive Substance Use

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    MODULE 2INTRODUCTION TO

    PSYCHOACTIVE SUBSTANCE USE

    Curriculum 1

    Physiology and Pharmacology for

    Addiction Professionals

    The Colombo Plan Asian Centre for Certification and Education of Addiction Professionals Training Series

    Curriculum 1

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    2.2

    Module 2 Learning Objectives

    Define psychoactive substance

    List general ways in which psychoactive

    substances affect mood, thoughts, and behavior

    List the four main categories (classes) of

    psychoactive substances and several substances

    within each

    List the methods of administering psychoactivesubstances

    Discuss the levels of progression of substance

    use

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    2.3

    Psychoactive Substances

    Affect the bodys central nervous system

    Change how people behave or perceive what

    is happening around them

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    2.4

    Central Nervous System

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    2.5

    BloodBrain Barrier

    Large, water-solublemolecules are

    blocked

    Small, fat-solublemolecules can enter

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    2.6

    Pharmacology

    Studies the effects of medications and other

    substances on the body and the brain

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    2.7

    Half-Life

    The amount of time it takes to eliminate half of

    the original dose of a substance from the body

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    2.8

    Other Factors

    A persons age, the length of time a person

    has regularly used a substance, and the

    amount of a substance regularly used affect

    how the body:Absorbs psychoactive substances

    Metabolizes them

    Eliminates them

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    2.9

    Psychoactive Substances

    Psychoactive substances alter:

    Mood

    Thoughts

    Sensory perceptions

    Behavior

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    2.10

    Effects of Psychoactive Substances

    Can be positive ornegative

    Depend to a large extent on the typeof

    substance used

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    2.11

    Drug Classes: Examples

    Stimulants Opioids

    (narcotics)

    Depressants Hallucinogens

    Cocaine Heroin Alcohol LSD

    Amphetamine Morphine BarbituratesMescaline

    Peyote

    Methamphetamine Opium Benzodiazepines Ecstasy

    Nicotine,

    Caffeine Demerol

    Gamma-

    Hydroxybutyrate

    (GHB); RohypnolMushrooms

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    2.12

    Legal Substances

    Just because a substance is legal does not

    mean it is safer than an illegal substance

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    2.13

    Other

    Some drugs do not fit neatly into a category:

    Cannabinoids (marijuana, hashish)

    Khat/Miraa

    Dissociative anesthetics (phencyclidine [PCP],ketamine)

    Inhalants solvents, gases, nitrites

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    2.14

    Routes of Administration

    Swallowing

    Snorting

    Smoking

    Inhaling fumes

    Intramuscular (IM) injection

    Subcutaneous (SC) injection

    Intravenous (IV) injection

    Topical

    Sublingual

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    2.15

    Routes of Administration

    The faster the drug hits the brain, the greater

    and more reinforcing its effect

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    2.16

    Speed of Action

    Smoking: 710 seconds

    Intravenous injecting: 1530 seconds

    Injecting into the muscle or under the skin: 35

    minutes

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    2.17

    Speed of Action

    Mucous membrane absorption (snorting,

    rectal): 35 minutes

    Swallowing: 2030 minutes

    Absorbed through skin: Slowly over a long

    period

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    2.18

    Small-Group Exercise: Routes of

    Administration

    Form small groups

    As a group, develop a list of any five

    psychoactive substances

    For each substance, list the most common

    routes of administration used in your area

    Keep in mind that some substances have

    more than one route of administration

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    2.19

    Break15 minutes

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    2.20

    Progression of Use

    Experimental/recreational use

    Circumstantial/Occasional use

    Intensified/regular use

    Compulsive/addictive use

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    2.21

    Learning Assessment

    Write one quiz question about todays material

    on a piece of paper

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    2.22

    Journal

    What did you learn today that you did not

    already know?

    How might you apply what you learned to your

    job?What questions do you still have?


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