Cancer and Mutation

Cancer and MutationClicker ReviewThis prevents uncontrolled cell division

OncogeneMutation Tumor-suppressor geneCarcinogen A substance that increases the risk of cancer

OncogeneMutation Tumor-suppressor geneCarcinogen A gene that causes cancer

OncogeneMutation Tumor-suppressor geneCarcinogen Changes in a cells DNA

OncogeneMutation Tumor-suppressor geneCarcinogen When cells spread beyond their original site

Mitosis Meiosis Metastasis Mutation What are normal genes that control a cells growth and differentiation called?

Tumor-suppressing genesOncogenes Proto-oncogenesGrowth factorsWhat type of cancer grows in the bone and muscle tissues?

Sarcoma LymphomaCarcinoma Carcinogen What type of cancer is lung cancer?

Sarcoma LymphomaCarcinoma Carcinogen What type of tumor invades and destroys healthy tissues?

MalignantMutation Oncogenes Benign Mutagens cause a(n)

MalignantMutation Oncogenes Benign A condition caused by a missing chromosome

MonosomyTurners syndromeTrisomyDowns syndromeBoth 1 and 2Both 3 and 4Which of the following is an example of a lethal mutation?

TriploidyMarfans syndromeCystic fibrousMonoploidy Both 1 and 4Both 2 and 3What are 2 proven risk factors that increase the chance a person will develop cancer?Select 2 numbers

Eating peanut butterSleeping AgeGenetics Which chromosome mutation will do the most damage to a zygote? The zygote will continue to develop and live

Translocation Deletion InsertionMonosomyWhich of the following is NOT a way a virus can induce cancer?

Activate an oncogeneMutate a proto-oncogeneCause exposure to a carcinogenMutate a tumor suppressor geneA gamete cell that has an extra chromosome is best explained by

Replication Nondisjunction Gene linkage Translocation An individuals chance of developing cancer increase if a cell has an oncogene and

Has a mutation in a tumor suppressor geneDoes not make growth factorsSelf-destructsAll of the aboveWhich mutation causes homologous chromosome not to separate properly during meiosis?

TranslocationInversion InsertionNondisjunction Which mutation causes a change in the single base pain in DNA?

Insertion Point mutation Frame shiftInversion What type of mutation is the picture?

InsertionInversion Deletion Nondisjunction What type of mutation is the picture?

Frame shiftTranslocation Addition Deletion

What type of mutation is the picture?

Translocation Deletion Addition Inversion Which mutation occurs when part of the chromosome breaks off and inserts itself backwards?

InsertionInversionsTranslocationNondisjunctionWhich mutation causes part of the chromosome to be left off?

Mutation Point mutationFrame shiftDeletionWhich mutation is when one chromosome breaks off and is attached to a different chromosome?

TranslocationInversionInsertionNondisjunctionWhich mutation occurs when nucleotides are added or deleted that disrupts the codon sequence?

Point mutationFrame shift mutationInversionInsertionWhich mutation is when part of a chromatid breaks off and reattaches to its sister chromatid?

TranslocationInversionInsertionNondisjunctionWhat is a mistake or change in DNA sequencing or pairing of chromosomes called?

Mutation Point mutationFrame shiftDeletionWhich of the following is a GENE mutation that does NOT produce a CHROMOSOMAL mutation

Point Insertion Nondisjunction Inversion Which of the following does NOT affect the organism, but can be passed to the offspring?

Somatic cellTranslocation Germ cellSubstitution What is the sex of the karyotype?

FemaleMaleWhich genetic disorder is shown in the karyotype?

KlinefeltersPatausTurnersDowns

Which genetic disorder is shown in the karyotype?

KlinefeltersPatausTurnersDowns

Letter A represents

ANormal body cellsSmall blood vesselsMetastasized cellsCancer cellsLetter B represents

BNormal body cellsSmall blood vesselsMetastasized cellsCancer cellsHow would you describe this mutation?

THE DOG BIT THE CATTHE DOB ITT HEC AT

Frame shift mutationDeletionGene mutationAll of the aboveBoth 1 and 2If the following picture represents a parent cell, which of the choices demonstrates crossing over?AAbBCcccAAABBb1.2.3.

EeEIf the following picture represents a parent cell, which of the choices demonstrates translocation?AABBCCCCAAABBB1.2.3.

If the following picture represents a parent cell, which of the choices demonstrates nondisjunction?AABBCCCCAAABBB1.2.3.

In dominant mutations

At least one allele must be dominantBoth alleles must be dominantAt least one allele must be recessive Both alleles must be recessiveIn recessive mutations

At least one allele must be dominantBoth alleles must be dominantAt least one allele must be recessive Both alleles must be recessive