+ All Categories
Home > Healthcare > Cancer and the immune system

Cancer and the immune system

Date post: 20-Mar-2017
Category:
Upload: nick-pellicciotta
View: 26 times
Download: 0 times
Share this document with a friend
69
Transcript
Page 1: Cancer and the immune system
Page 2: Cancer and the immune system

than in non-vegetarians.

Cancer incidence among California Seventh-day Adventists, 1976-1982.

American Journal of Clinical Nutrition 1994, 59(supplement):1136S-1142S

Page 3: Cancer and the immune system

•Incidence of breast and prostate Incidence of breast and prostate cancer less in vegetarianscancer less in vegetarians

• Incidence of ovarian and Incidence of ovarian and endometrial cancer less in endometrial cancer less in vegetariansvegetarians

• Incidence of skin cancer and Incidence of skin cancer and brain cancer less in vegetariansbrain cancer less in vegetarians

Page 4: Cancer and the immune system

STEPS TO CANCERStep 1:A. InitiationA. Free radicals get

into the cell’s nucleus and damage the DNA.

F ree ra d ic a ls

D N AA n tio x id a n ts

N u cle u s

Page 5: Cancer and the immune system

FREE RADICALS

• Trauma, injury, inflammation• Excessive exercise

• Smog

• High fat diet• Overeating

Page 6: Cancer and the immune system

FREE RADICALS

• Excessive radiation in general • Too much ultra violet light

• Aging

• Too much or too little oxygen for too long

Page 7: Cancer and the immune system

STEPS TO CANCERStep 1:A. Initiation

First line defenseA cell has the ability to repair it’s own DNA or even cut out the damaged DNA strand.

F ree ra d ica ls

D N AA n tio x id a n ts

N u cle u s

Page 8: Cancer and the immune system

STEPS TO CANCER

Note: Antioxidants, such as lycopene, vitamins A, C, E, selenium and genistein stop the free radicals from harming the cell.

F ree ra d ica ls

D N AA n tio x id a n ts

N u cle u s

Step 1:A. Initiation

Page 9: Cancer and the immune system

ANTIOXIDANT RICH FRUITS• Strawberries• Blueberries• Plums• Oranges & grapefruit, all citrus• Kiwi fruits• Grapes, especially muscadine varieties• Bananas• Apples • Tomatoes

Page 10: Cancer and the immune system

ANTIOXIDANT RICH VEGGIES• Garlic• Kale• Spinach• Brussels

Sprouts• Alfalfa sprouts• Broccoli• Beets• Red bell pepper• Onion• Corn

Page 11: Cancer and the immune system

STEPS TO CANCER

A. Most cancer causing chemicals enter the body as procarcinogens.

P h a s e IE n z y m es

P ro ca rc in o g en s

C a rc in og en s

Step 1:B. Initiation -1st line of defense

Page 12: Cancer and the immune system

STEPS TO CANCER

B. In order for them to become dangerous, carcinogens capable of damaging DNA must first be broken down by phase I enzymes produced in the liver.

P h a s e IE n z y m es

P ro ca rc in o g en s

C a rc in og en s

Step 1:B. Initiation -1st line of defense

Page 13: Cancer and the immune system

STEPS TO CANCER

C. Foods to the RescueGarlic contains allyl sulfides, which limit the production of phase I enzymes.

Step 1:B. Initiation – 1st line of defense

Page 14: Cancer and the immune system

STEPS TO CANCER

The liver also produces phase II enzymes to cart off the dangerous residue that the phase I enzymes leave behind.

Step 1:B. Initiation – 1st line of defense

Page 15: Cancer and the immune system

STEPS TO CANCER

C. Foods to the RescueCruciferous vegetables, rich in sulforaphane, boost the production of phase II enzymes.

Step 1:B Initiation – 1st line of defense

Page 16: Cancer and the immune system

STEPS TO CANCER

C. Foods to the RescueVitamin C prevents the formation of carcinogens from nitrates in the colon.

Step 1:B. Initiation – 1st line of defense

Page 17: Cancer and the immune system

STEPS TO CANCER

C. Foods to the RescueDietary fibers, increase the elimination of carcinogens from the body.

Step 1:B. Initiation – 1st line of defense

Page 18: Cancer and the immune system

STEPS TO CANCER

If first line defenses fail and a cell undergoes potentially cancerous changes, the body’s best defense is to destroy the cell or to keep it from dividing rapidly.

O m e g a -3 F a tty A cid s

D a m a g ed D N A

O m eg a -6F a tty A cid s

Step 2:A. Promotion – 2nd line of defense

Page 19: Cancer and the immune system

STEPS TO CANCER

A. The omega-6 fatty acids found in corn and safflower oil seem to promote rapid cell division.

O m e g a -3 F a tty A cid s

D a m a g ed D N A

O m eg a -6F a tty A cid s

Step 2:A. Promotion

Page 20: Cancer and the immune system

STEPS TO CANCER

A. The omega-3 fatty acids in flax and olives may thwart tumor growth by crowding other fats out of cells.

O m e g a -3 F a tty A cid s

D a m a g ed D N A

O m eg a -6F a tty A cid s

Step 2:A. Promotion

Page 21: Cancer and the immune system

STEPS TO CANCER

B. Reproductive tissues are particularly cancer-prone, dividing rapidly when triggered by the body’s own sex hormones. Estrogen promotes fast growth of breast cells in woman.

Step 2:B. Promotion

E stro g en R ecep to r s

P la n t E stro g en

B o d y ’s E stro g en

Page 22: Cancer and the immune system

STEPS TO CANCER

B. Soy products contain isoflavones, which act as estrogen leaving less room for the body’s estrogen.

E stro g en R ecep to r s

P la n t E stro g en

B o d y ’s E stro g en

Step 2:B. Promotion – 2nd line of defense

Page 23: Cancer and the immune system
Page 24: Cancer and the immune system

World Cancer Research Fund and American Institute for Cancer, “Food,

Nutrition and the Prevention of Cancer: A Global Perspective,” 1997, 456-457

Page 25: Cancer and the immune system

Breast cancer rates are much lower in populations that consume plant based

diets.American Cancer Society, Cancer Facts

and Figures, 1994

Page 26: Cancer and the immune system

A causal relationship between red meat consumption and cancer is

supported by several large studies conducted in the U.S. Specifically,

women with the highest level of meat consumption had double the rate of breast cancer compared to

those who consumed a small amount of meat.

Epidemiology, 5:4(1994), 391

Page 27: Cancer and the immune system

FAT INTAKE: BREAST CANCER

F em a le

To ta l d ie ta ry fa t in ta k e (g m /d a y ) 1 9 44 -6 6

A g e a d ju sted d ea th ra te /1 0 0 ,0 0 0 p o p u la tio n (1 9 70 )

2 5

2 0

1 5

1 0

5

2 0 4 0 6 0 8 0 1 0 0 1 2 0 1 4 0 1 6 0

M ex icoVen ezu e la

T h a ila n dJ a p a n

P o lan dG reece

H on g K o n g

P o rtu g a l F in la n d

A u stra liaS w ed en

F ran ce

M alta W est G erm a n y

C a n a d aU S A

Page 28: Cancer and the immune system

FOODS HIGH IN FATS

Milk

Cheese

Eggs

Meat

Page 29: Cancer and the immune system

Using a macrobiotic diet emphasizing Using a macrobiotic diet emphasizing whole grains, vegetables, and legumeswhole grains, vegetables, and legumes while avoiding dairy products and most while avoiding dairy products and most meats, nine men with meats, nine men with prostate cancerprostate cancer

had an average survival of 228 months, had an average survival of 228 months, compared to 72 months for a matched compared to 72 months for a matched

group of men using no special diet.group of men using no special diet.

Journal of the American College of Nutrition, 1993; 12 209-26

Page 30: Cancer and the immune system

With the exception of tobacco consumption,

in the etiology of human cancer.Toxicology, December, 2002, Volume 181-182

Page 31: Cancer and the immune system

Vegans tend to have low serum lipids, lean physiques, later puberty, and decreased

risk for certain prominent ‘Western’ cancers; a vegan

diet has documented clinical efficacy in rheumatoid

arthritis. Medical Hypotheses, 1999 Dec; 53(6):459-85

Page 32: Cancer and the immune system

This diet has a comprehensive ability to control the expression of the genes that predispose to many diseases such as heart

disease, cancer, diabetes, obesity, childhood allergies,

osteoporosis.

T. Colin Campbell, Ph.D. Cornell University, “The China Study”

Page 33: Cancer and the immune system

The matched subjects who ate meat (including poultry and fish) were more than twice as likely to

become demented as their vegetarian counterparts.

Neuroepidemiology, 1993; 12(1):28-36

Page 34: Cancer and the immune system

Evidence suggests that most of the chronic degenerative diseases can be reversed or

at least suspended from further development, by

consuming a plant-based diet.

T. Colin Campbell, Ph.D. Cornell University, “The China Study”

Page 35: Cancer and the immune system

Pancreatic cancer occurs much more frequently in countries

where fat consumption and/or animal product consumption is

high.American Journal of

Epidemiology, 1990; 132:423-431

Page 36: Cancer and the immune system

Prostate cancer patients consume a diet higher in fat, meat, & dairy products than

those who do not have prostate cancer. And, the

higher the consumption, the higher the death rate. Cancer, 1989; 64:598-604

Page 37: Cancer and the immune system

Cancer odds ratios for the highest percentiles of red meat intake (7 or

more times per week) compared with the lowest (3 or fewer times per

week) were 1.6 for stomach, 1.9 for colon, 1.7 for rectal, 1.6 for

pancreatic, 1.6 for bladder, 1.2 for breast, 1.5 for endometrial and 1.3

for ovarian cancer.

International Journal of Cancer, May 1, 2000, 86:425-428

Page 38: Cancer and the immune system

High-vegetable fiber intakes reduces risk factors for

cardiovascular disease and colon cancer.

Metabolism, 2001 Apr; 50(4):494-503

Page 39: Cancer and the immune system

Low-fat vegan diets are especially protective in

regard to cancers linked to insulin resistance – namely, breast and colon cancer – as

well as prostate cancer;

Medical Hypotheses, 1999 Dec; 53(6):459-85

Page 40: Cancer and the immune system

Nine studies of childhood brain tumors and maternal diet during

pregnancy have focused on foods. An association between frequent consumption of cured

meat (hot dogs, baloney) by pregnant women and increased

risk is a consistent finding in most of the studies.

International Journal of Cancer, Suppl. 1998; 11:23-5

Page 41: Cancer and the immune system

Intake of legumes lowers the risks of colon cancer and pancreatic cancer.

Higher consumption of all fruit or dried fruit was associated with lower risks of lung, prostate, and pancreatic cancers.

American Journal of Clinical Nutrition, 1999 Sep; 70 (3 Suppl):532S-538S

Page 42: Cancer and the immune system

Researchers followed 384 men with prostate cancer over a five-year

period…those who consumed the most saturated fat - the kind

particularly prevalent in meats and dairy products-had three times the

risk of dying from the disease, compared to those with the lowest

saturated fat intake.European Journal of Urology, 1999; 388:91

Page 43: Cancer and the immune system

Evidence strongly suggests that a high intake of plant-based foods, and a low intake of animal products contribute to the excellent health of Mediterranean

populations. The high consumption of red meat in Western diets is associated

with calcium losses likely to contribute to osteoporosis.

American Journal Clinical Nutrition, 1995; 61, 1416

Page 44: Cancer and the immune system

Data are strong that vegetarians are at lesser risk

for alcoholism.

American Journal of Clinical Nutrition, 1988 Sep; 48 (3Suppl):712-38

Page 45: Cancer and the immune system

84 prostate cancer men who were able to defer treatment because of a careful

watch on their prostate-specific antigen (PSA). Half the men were assigned to

usual care (control group) and the remaining half to a low-fat, vegan diet, along with regular exercise and stress

management.

Urology, 2001; 57(4 Suppl 1):200-1

Page 46: Cancer and the immune system

In the control group, the PSA levels rose over the three-month study period, and 7 required additional treatment. But in the 42 men assigned to the vegan diet and lifestyle intervention, the average PSA level dropped from 6.3 to 5.8, and none

required further treatment.

Urology, 2001; 57(4 Suppl 1):200-1

Page 47: Cancer and the immune system

The beneficial effects of consuming a plant-based diet

can only be fully appreciated and demonstrated when it is

understood that nutrients work in concert.

T. Colin Campbell, Ph.D. Cornell University, “The China Study”

Page 48: Cancer and the immune system

Every 12 minutes someone dies from breast cancer. Yet women who eat as few as two

servings of vegetables per day reduce their breast

cancer risk by 30%.

Annals of the New York Academy of Science, 768(Sept. 30, 1995): 1-11

Page 49: Cancer and the immune system

Eating a diet rich in plant foods, remains the best

option for reducing the risk of colon cancer; and general

health protection.

The Lancet, May 3, 2003, Volume 361, p 1448

Page 50: Cancer and the immune system

One study tested mostly raw vegan diet in 30 patients with fibromyalgia, syndrome of chronic fatigue, pain,

poor sleep, depression, and anxiety. After several months on the diet, 19

participants showed signs of improvement in range of motion, flexibility, and other measures.

BMC Complementary Alternative Medicine, 2001; 1:7

Page 51: Cancer and the immune system

High protein diets impair High protein diets impair mental functioning.mental functioning.

International Journal of Obesity,

Related Metabolic Disorders, 1995; 19:811

Page 52: Cancer and the immune system

Cow’s milk, especially processed cow’s milk, has been linked to a variety of health problems, including: mucous production, hemoglobin loss, childhood diabetes, heart disease, atherosclerosis, arthritis, kidney stones, mood swings, depression, irritability, and allergies.

Townsend Medical Letter, May 1995; Julie Klotter, MD

Page 53: Cancer and the immune system

Review• Daniel’s Experience

– Do not defile self– Saved unto good works– Good works help us

• Walk with God• Witness to others• Make a gift to God• Bring good to family

Cannot safely break even the least commandment

• Laws of God– Laws of the mind

• Train to dwell on heavenly themes

• Resist discontent• Encourage calmness• What is in the mind will

be expressed, which strengthens it

• True sanctification is loving God supremely and harmonizing with Him.

• Harmonizing with God involves Habit training

Page 54: Cancer and the immune system

Daniel’s ExperienceDo not defile selfSaved unto good worksGood works help us

Walk with GodWitness to othersMake a gift to GodBring good to family

Cannot safely break even the least commandment

Page 55: Cancer and the immune system

Basal cell carcinoma

Page 56: Cancer and the immune system
Page 57: Cancer and the immune system
Page 58: Cancer and the immune system
Page 59: Cancer and the immune system

Skin Cancer

Asymmetry

Border

Page 60: Cancer and the immune system

Skin Cancer

Color

Diameter

Page 61: Cancer and the immune system

Breast Cyst

Fibrocystic

Alteration

Fibroadeoma

Normal

Breast

Page 62: Cancer and the immune system
Page 63: Cancer and the immune system

NormalDuct Invasive

DuctalCarcinoma

Hyperplasia

AtypicalHyperplasia

DuctalCarcinoma

In-Situ

What Does Cancer Look

Like?

Symptoms of CarcinomaDimpling of skin like an orangePainless or painful lumpRetracted nippleBloody discharge from nippleChange in contour of breast

Page 64: Cancer and the immune system
Page 65: Cancer and the immune system
Page 66: Cancer and the immune system

•Fats are designated as:

Unsaturated

Saturated

Polyunsaturated

Monounsaturated

solid at room temperature

liquids at room temperature

Page 67: Cancer and the immune system

Women eating the highest amounts of red meats,

sweets, French fries and refined grains had

1.5 times the risk of colon cancer1.5 times the risk of colon cancer of women who ate more fruits,

vegetables, fish and whole grains.Archives of Internal Medicine, Volume 4, Number 36; February 14, 2003

Page 68: Cancer and the immune system

An association was found between consumption of red meat, particularly processed meat, and risk of colorectal

cancer, which corresponds with current advice to limit intakes of

red meat and meat products.Cancer Epidemiology,

Biomarkers and Prevention, 2001; 10: 439-446

Page 69: Cancer and the immune system

40% of the world’s cancer cases could be prevented through the adoption of diets rich in grains, fruit and vegetables. (Still use

meat, however!)American Institute for Cancer Research; World Cancer Fund

10/16/97


Recommended