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Carbonyl Chemistry Survey of Reactions and Mechanisms Part 5 Oxaloacetate NADH Malate NAD + O O O O O + O O O O OH + N H H O NH 2 N O NH 2 C O Carbonyl Reduction Reactions •C=O reduction important in synthesis and biology •But how is this reduction? Reduction = gain electrons...? Reduction: Increase in the number of bonds between C and elements less electronegative than C (often H). Oxidation: Increase in the number of bonds between C and elements more electronegative than C (often O). Generalized transformation : Reduction Add one C-H bond ______electrons ______electrons C OH H Oxidation Add one C-O bond
