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CARCINOMA MAMMÆ IN A YOUNG AND HEALTHY WOMAN

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446 three-branched urethra-dilator was introduced, and the canal thereby dilated in the course of five minutes sufficiently to allow of the introduction of a pair of very slender, straight lithotomy-forceps into the bladder. The stone was almost at once grasped and removed by somewhat forcible extracting movements steadily continued for about a minute, the stone having fortunately been grasped exactly in the most favourable direction. After the operation, a dose of tincture of hyos- cyamus, and abundance of barley-water, were given. Description of the stone.—The stone was of an ovoid form, thickly studded externally with small, sharp prominences. It measured rather more than two inches in its longest circum- ference, and nearly one inch and three quarters in its shortest circumference. It was composed of oxalate of lime. Result.---The child suffered only a moderate amount of pain in passing urine for three days after the operation, and it was slightly tinged with blood for about six days; but no untoward symptom of any kind occurred, and she was discharged thirty- four days after the operation, much fatter than on her admis- sion, cheerful, and in all respects well, having full ability to retain the urine naturally and healthily. CLINICAL RECORDS. THREE CASES OF ULCER OF THE STOMACH. WHENEVER hæmatemesis occurs, the blood being pure, the practitioner may have good cause to fear an ulcer of the stomach, which may be verified by the history and physical examination of the patient. The latter, we need not urge, should be very carefully done, as unfortunately, from rude handling, the ulcer iiiiaht be converted into an actual perfora- tion. Three well-marked cases of ulcus ventriculi are to be seen at the present moment (Oct. 19th), at the Royal Free Hospital, under Dr. Brinton’s care. The first of these is iu a young girl, twenty years of age, who has had hæmatemesis for about a month, followed by pallor and weakness. She was treated during the first week by iced milk and arrowroot, and subsequently by fish and then a stewed chop daily, as the stomach would bear it. This was followed by good results, as the hæmatemesis ceased. She is now taking small doses of quinine and iron, with about one-third of a grain of opium in the day, and, on the whole, her improvement is very satisfactory. In the second case, the patient is quite blanched, and has had re- peated vomiting of blood, with gastrodynia for a twelvemonth. The bleeding is very difficult to stop-it ceases for a time, and any slight cause produces it. Dr. Brinton believes that one of the branches of the splenic artery most probably opens into the ulcer, and when the plug of coagulated blood is detached the hæmorrhage commences. She is fed principally by enemata, has ice-water to drink, and cold applied over the stomach. All the styptics which were here tried proved of no avail what- ever. The first patient, we should observe, always menstruates regularly, although the quantity is variable. It is unusual to see so many cases of this affection in an hospital together, but it often happens, that more than one example of a peculiar disease come together. These three patients are side by side in their different beds. We also noticed another instance of this affection, at the St. Pancras Dispensary, on the 20th of October, under Dr. Gibb’s care, in a girl aged twenty years, who has had hæmatemesis at intervals for the last three months, but with general bad health for the last two years. SPONTANEOUS AMPUTATION OF FOUR FINGERS WITH A SAUSAGE-CHOPPER. THE accident in this case was rather a singular one. A boy aged eighteen was manipulating with some sausage-meat on October 12th, when the sausage-chopper merely wounded him in the right hand, as he thought. He quickly drew up his hand, and to his astonishment found the four fingers were as completely cut off at their metacarpal articulations as if done with an amputating-knife, the thumb fortunately remaining intact. He was admitted into St. Bartholomew’s Hospital, under Mr. Skey’s care, but was seen, on admission, by Mr. Barker, the house-surgeon, who removed the heads of the four metacarpal bones, and brought the lips of the wound together by sutures. We saw the boy, on the 17th of October, in Abernethy ward, and at that time the greater part of the stump had united by adhesion, with some suppuration of the other part. The hand will be a useful one with the thumb, AMPUTATION AT THE SHOULDER-JOINT FOR MYELOID DISEASE. THE patient was a young woman twenty-five years of age, the mother of five children, who, in September, 1856, had pain in her left shoulder, and was treated for rheumatism. The pain continued for some time. Three months before September, it became painful, and in a month it began to swell. Her sufferings now were extreme, and she was admitted into the Middlesex Hospital on the 8th of September. The swelling was situated at the great tuberosity, and was as large as an orange, covered with integument, which was partly adherent. The pain continued to be agonizing, and she had no sleep. Amputation was performed at the joint by Mr. Mitchell Henry, and on examining the diseased joint afterwards, fracture of the hmnerus was found to have taken place just below the head of the bone. She made a good recovery, and was to leave the hospital this month (October.) The tumour proved to be fibro. plastic, which Mr. Henry stated had become ossified at its lower part, which was evidently growing at the time of the operation. The fractured part of the bone is soft, and filled with myeloid cells. The shaft of the bone was prolonged into the disease, and had not undergone any change, but most pro- bably the disease had commenced in the interior of that part of the bone which was expanded. Although Mr. Henry thinks this form of disease should not be called myeloid, we prefer to give it the name assigned to it by such pathologists as Mr. Paget, Lebert, and Henry Gray. ENCEPHALOID CANCER OF THE TESTICLE. MR. CURLING mentions, in his work on "Diseases of the Testis," that medullary cancer is by far the most frequent dis. ease of a malignant character to which the testicle is liable, and occurs at all ages, but most commonly at the middle period of life. We have already placed upon record instances in which it has been present in children. A good example of this form of cancer occurred but the other day at St. George’s Hospital, under the care of Mr. Caesar Hawkins, in a middle-aged man, whose left testicle was enlarged to the size of a Spanish onion. It had not been growing very long, but the body of the testicle was distinguishable for some time, preserving its oval form, which finally became lost. Mr. Hawkins removed the testicle, under chloroform, on the 15th of October, completely isolating the growth before dividing the spermatic cord, which was effected on holding it with a piece of linen. Unfortunately, the artery retracted within the canal, and was not secured for some time; its retraction caused the spermatic cord to curve inwards like a hook. A section of the testicle showed the true characters of the disease, with a mixture of yellow, degenerated, cancerous substance, the testis being completely lost in the mass itself. The man is doing well, and will most probably recover from the effects of the operation. How long he may remain free from a return of the disease elsewhere is a matter for reflection and anxiety. Mr. Hawkins, however, in 1841, removed a testicle similarly affected (which is preserved in the museum of St. George’s Hospital) from a patient, who was alive and well in 1853. This circumstance is of interesting moment in relation to the operation, and is sufficiently en- couraging to permit of the hope of delay in the recurrence of this sad disease. __ CARCINOMA MAMMÆ IN A YOUNG AND HEALTHY WOMAN. WE know very well that scirrhus is by no means of rare occurrence in the young, and should not be surprised to meet with it in cases which, somehow or other do still form excep- tions to the general rule, when we consider the peculiar organ involved. The breast of the female is attacked with cancer beyond the age of forty, but when it is seen in the organ of one some years younger, it naturally attracts some attention. This will explain why the tumours of the breast in young women are for the most part simple and innocuous. At Guy’s Hospital on the 13th of October, Mr. Birkett re-- moved from the breast of a fine, healthy-looking young woman, thirty-five years of age, a tumour the size of a walnut, which did not give the usual characters of an adenocele, as it seemed to be incorporated with the breast; but the nipple was healthy and natural, and there were no external appearances whatever indicative of cancer. On excising it, two small cysts were found on its anterior part, but the structure was truly carei- nomatous, with a dovetailing of the gland tissue with the malignant growth, and a little elevated division formed by the latter. It had been but a few months growing, and doubtless will return, as one of the small axillary glands was affected. A case somewhat similar to this, only that the age was
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Page 1: CARCINOMA MAMMÆ IN A YOUNG AND HEALTHY WOMAN

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three-branched urethra-dilator was introduced, and the canalthereby dilated in the course of five minutes sufficiently toallow of the introduction of a pair of very slender, straightlithotomy-forceps into the bladder. The stone was almost atonce grasped and removed by somewhat forcible extractingmovements steadily continued for about a minute, the stonehaving fortunately been grasped exactly in the most favourabledirection. After the operation, a dose of tincture of hyos-cyamus, and abundance of barley-water, were given.Description of the stone.—The stone was of an ovoid form,

thickly studded externally with small, sharp prominences. Itmeasured rather more than two inches in its longest circum-ference, and nearly one inch and three quarters in its shortestcircumference. It was composed of oxalate of lime.

Result.---The child suffered only a moderate amount of painin passing urine for three days after the operation, and it wasslightly tinged with blood for about six days; but no untowardsymptom of any kind occurred, and she was discharged thirty-four days after the operation, much fatter than on her admis-sion, cheerful, and in all respects well, having full ability toretain the urine naturally and healthily.

CLINICAL RECORDS.

THREE CASES OF ULCER OF THE STOMACH.

WHENEVER hæmatemesis occurs, the blood being pure, thepractitioner may have good cause to fear an ulcer of thestomach, which may be verified by the history and physicalexamination of the patient. The latter, we need not urge,should be very carefully done, as unfortunately, from rudehandling, the ulcer iiiiaht be converted into an actual perfora-tion. Three well-marked cases of ulcus ventriculi are to beseen at the present moment (Oct. 19th), at the Royal FreeHospital, under Dr. Brinton’s care. The first of these is iu a

young girl, twenty years of age, who has had hæmatemesis forabout a month, followed by pallor and weakness. She wastreated during the first week by iced milk and arrowroot, andsubsequently by fish and then a stewed chop daily, as the stomachwould bear it. This was followed by good results, as thehæmatemesis ceased. She is now taking small doses of quinineand iron, with about one-third of a grain of opium in the day,and, on the whole, her improvement is very satisfactory. Inthe second case, the patient is quite blanched, and has had re-peated vomiting of blood, with gastrodynia for a twelvemonth.The bleeding is very difficult to stop-it ceases for a time, andany slight cause produces it. Dr. Brinton believes that one ofthe branches of the splenic artery most probably opens into theulcer, and when the plug of coagulated blood is detached thehæmorrhage commences. She is fed principally by enemata,has ice-water to drink, and cold applied over the stomach.All the styptics which were here tried proved of no avail what-ever. The first patient, we should observe, always menstruatesregularly, although the quantity is variable. It is unusual tosee so many cases of this affection in an hospital together, butit often happens, that more than one example of a peculiardisease come together. These three patients are side by sidein their different beds. We also noticed another instance ofthis affection, at the St. Pancras Dispensary, on the 20th ofOctober, under Dr. Gibb’s care, in a girl aged twenty years,who has had hæmatemesis at intervals for the last three months,but with general bad health for the last two years.

SPONTANEOUS AMPUTATION OF FOUR FINGERS WITH A

SAUSAGE-CHOPPER.

THE accident in this case was rather a singular one. A boyaged eighteen was manipulating with some sausage-meat onOctober 12th, when the sausage-chopper merely wounded himin the right hand, as he thought. He quickly drew up hishand, and to his astonishment found the four fingers were ascompletely cut off at their metacarpal articulations as if donewith an amputating-knife, the thumb fortunately remainingintact. He was admitted into St. Bartholomew’s Hospital,under Mr. Skey’s care, but was seen, on admission, by Mr.Barker, the house-surgeon, who removed the heads of the fourmetacarpal bones, and brought the lips of the wound togetherby sutures. We saw the boy, on the 17th of October, inAbernethy ward, and at that time the greater part of thestump had united by adhesion, with some suppuration of theother part. The hand will be a useful one with the thumb,

AMPUTATION AT THE SHOULDER-JOINT FOR MYELOID DISEASE.

THE patient was a young woman twenty-five years of age,the mother of five children, who, in September, 1856, had painin her left shoulder, and was treated for rheumatism. The

pain continued for some time. Three months before September,it became painful, and in a month it began to swell. Hersufferings now were extreme, and she was admitted into theMiddlesex Hospital on the 8th of September. The swellingwas situated at the great tuberosity, and was as large as anorange, covered with integument, which was partly adherent.The pain continued to be agonizing, and she had no sleep.Amputation was performed at the joint by Mr. Mitchell Henry,and on examining the diseased joint afterwards, fracture of thehmnerus was found to have taken place just below the head ofthe bone. She made a good recovery, and was to leave thehospital this month (October.) The tumour proved to be fibro.plastic, which Mr. Henry stated had become ossified at itslower part, which was evidently growing at the time of theoperation. The fractured part of the bone is soft, and filledwith myeloid cells. The shaft of the bone was prolonged intothe disease, and had not undergone any change, but most pro-bably the disease had commenced in the interior of that part ofthe bone which was expanded. Although Mr. Henry thinksthis form of disease should not be called myeloid, we prefer togive it the name assigned to it by such pathologists as Mr.Paget, Lebert, and Henry Gray.

ENCEPHALOID CANCER OF THE TESTICLE.

MR. CURLING mentions, in his work on "Diseases of theTestis," that medullary cancer is by far the most frequent dis.ease of a malignant character to which the testicle is liable,and occurs at all ages, but most commonly at the middle periodof life. We have already placed upon record instances in whichit has been present in children. A good example of this formof cancer occurred but the other day at St. George’s Hospital,under the care of Mr. Caesar Hawkins, in a middle-aged man,whose left testicle was enlarged to the size of a Spanish onion.It had not been growing very long, but the body of the testiclewas distinguishable for some time, preserving its oval form,which finally became lost. Mr. Hawkins removed the testicle,under chloroform, on the 15th of October, completely isolatingthe growth before dividing the spermatic cord, which waseffected on holding it with a piece of linen. Unfortunately,the artery retracted within the canal, and was not secured forsome time; its retraction caused the spermatic cord to curveinwards like a hook. A section of the testicle showed the truecharacters of the disease, with a mixture of yellow, degenerated,cancerous substance, the testis being completely lost in themass itself. The man is doing well, and will most probablyrecover from the effects of the operation. How long he mayremain free from a return of the disease elsewhere is a matterfor reflection and anxiety. Mr. Hawkins, however, in 1841,removed a testicle similarly affected (which is preserved in themuseum of St. George’s Hospital) from a patient, who wasalive and well in 1853. This circumstance is of interestingmoment in relation to the operation, and is sufficiently en-couraging to permit of the hope of delay in the recurrenceof this sad disease.

__

CARCINOMA MAMMÆ IN A YOUNG AND HEALTHY WOMAN.

WE know very well that scirrhus is by no means of rareoccurrence in the young, and should not be surprised to meetwith it in cases which, somehow or other do still form excep-tions to the general rule, when we consider the peculiar organinvolved. The breast of the female is attacked with cancerbeyond the age of forty, but when it is seen in the organ ofone some years younger, it naturally attracts some attention.This will explain why the tumours of the breast in youngwomen are for the most part simple and innocuous.At Guy’s Hospital on the 13th of October, Mr. Birkett re--

moved from the breast of a fine, healthy-looking young woman,thirty-five years of age, a tumour the size of a walnut, whichdid not give the usual characters of an adenocele, as it seemedto be incorporated with the breast; but the nipple was healthyand natural, and there were no external appearances whateverindicative of cancer. On excising it, two small cysts werefound on its anterior part, but the structure was truly carei-nomatous, with a dovetailing of the gland tissue with themalignant growth, and a little elevated division formed by thelatter. It had been but a few months growing, and doubtlesswill return, as one of the small axillary glands was affected.A case somewhat similar to this, only that the age was

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greater, was submitted to operation by Mr. Fergusson, atKing’s College Hospital, on the 10th of October. The tumourwas small, occupied a part of the breast for nearly five years, Ifelt like a fibrous tumour, but on section turned out to becarcinoma.We will remark that Mr. Birkett’s patient had the operation

done without chloroform, and did not evince the slightest in-dication of pain; nor did she move in any degree whatsoever.

HYDROCOTYLE ASIATICA.

THIS is the name of a new drug which has lately been muchused in France in the treatment of certain cutaneous affections.The Hydrocotyle Asiatica is an umbelliferous plant, found inthe eastern portion of the Asiatic continent, and was intro-duced to the notice of the Imperial Academy of Medicine ofParis, by M. Lepine. The action of the drug has been testedby MM. Cazenave and Devergie, of the Hopital St. Louis,who have, as far as experiments have been made, reportedfavourably upon its merits. The form of administration is ingranules or syrup. An hydro-alcoholic extract is obtained invacuum, which prevents deterioration by atmospheric influ-ence, as the plant itself rapidly undergoes change. It exercisesa particular virtue over various cutaneous affections, particu-larly those of long standing and dependent on the presence ofsyphilitic or scrofulous taint. It has been administered withsuccess in cases of leprosy and elephantiasis. M. Cazenavereporta that its effects are remarkable and constant. It causesa considerable augmentation in the secretion of the urine, andan increase in the heat of the skin. When given in excess, itproduces copious sweats, a sensation of heaviness, uneasiness,and giddiness of the head. We believe that little notice hasas yet been taken of this new medicine in this country. Mr. ’,Price, however, has been trying its efficacy at the GreatNorthern Hospital, and also at the Blenheim Free Dispensary,and has found that benefit has certainly followed its use insome instances of obstinate syphilitic eruptions, and in chroniceczemas. The preparations are to be obtained of Messrs.Savory and Moore, of :New Bond-street.

Provincial Hospital Reports.NEWCASTLE INFIRMARY.

EXCISION OF THE OS CALCIS.

(Under the care of Mr. CHARLES JOHN GIBB.)(Reported by LUKE ARMSTRONG, Esq., Dresser.)

JOHN S-, aged forty, labourer, was admitted into theNewcastle Infirmary on April 23rd, 1857, with scrofulous

disease of the os calcis. There was a slight purulent dischargefrom several fistulous openings, which led down to the diseasedbone. The foot was much swollen, and he complained of greatpain. Poultices were applied to the foot, and an opiate wasadministered every night.After a careful examination, Mr. Gibb came to the conclu-

sion that the os calcis was alone implicated. On the 27th,operative proceedings having been determined upon, the patientwas placed under the influence of chloroform, and Mr. Gibbremoved the entire bone. The articular surfaces were foundsound, the seat of the bone was softened, and in several placesdestroyed, by carious ulceration. No haemorrhage followedthe operation. The foot was placed upon a side splint, andfixed in such a position that the heel could be dressed withoutallowing the slightest movement of the ankle-joint. Thepatient was allowed generous diet, with a pint of ale daily.The case proceeded very favourably until ten days after theoperation, when the pressure of the splint having caused thefoot to ulcerate, it was found necessary to readjust it; andnotwithstanding the greatest care was observed in its removal,a slight amount of inflammation was set up, and the foot againswelled to a considerable extent. The splint was then allowedto remain on a fortnight without being disturbed, during whichtime the inflammation gradually subsided.On the 20th of August the patient was discharged cured.

The swelling had entirely disappeared, and the wound caused,by the operation was healed. There remains very little de-formity of the foot, and the patient has perfect use of theankle-joint.

Medical Societies.MEDICAL SOCIETY OF LONDON.

SATURDAY, OCTOBER 24TH, 1857.MR. HIRD, PRESIDENT, IN THE CHAIR.

EPITHELIAL CANCER.-NEW CAUSTIC.

MR. HENRY THOMPSON requested the attention of the Societyto the case of a woman, aged seventy, who was present for thepurpose. In July last, he saw her for the first time, with anepithelial growth, the size of a large walnut, close to the righteye. It was too close to remove entirely with the knife. Hetherefore employed a caustic, which, after six applications, haddestroyed it completely. On examining the woman, a healthycicatrix alone remained, and no trace of disease was seen. Theescharotic employed was the strong sulphuric acid of commerce,made into a paste with the exsiccated sulphate of zinc. Mr.Thompson believed that the employment of escharotics for theremoval of cancerous growths could only be justified in excep.tional cases, but that this was, from the circumstances named,one in which it was decidedly preferable to the knife.

Mr. HANCOCK had removed many cases of a similar kindwith the knife, but he never saw so perfect a cure by anymeans as the present case exhibited. There was scarcely anyscar.

Mr. POLAND could not regard the case as one of cure, andrelated an instance in which a similar growth had successivelyattacked the neighbourhood of the eye, involving the conjunc-tiva. Escharotics were applied on several occasions, but thedisease returned. The disease was eventually removed by theknife, and at present all seemed doing well.

Mr. JABEZ HoGG exhibited a specimen of carcinoma of themamma, taken from a bitch.

Mr. HANCOCK exhibited the bones of the ankle-joint excisedfrom a patient a fortnight ago. The patient is doing very well.

Dr. HUGHES WILLSHIRE exhibited a specimen of"INKOMANCOMO,"

an agent in great repute amongst the Zulu Kaffirs in the treat-ment of tapeworm. The drug in question is the rhizoma ofAspidium athamanticum of Kunze, a fern closely allied to theLastrcea filix mas, from which the etherial solution of the oleo-resin now getting into use amongst ourselves is manufactured.Dr. Willshire stated that he was indebted to the kindness ofMr. Perkins, of Exeter, fo the specimen, who received it fromone of his pupils resident for some years at Port Natal.According to the latter, "the Zulu Kaffirs take one teaspoonfulof the powder in some fluid, fasting, with great efficacy."Reference had been made by Dr. Willshire to this agent in apaper he placed before the Society last year. (THE LANCET,vol. 1857, March 9th, p. 475.)

Dr. HEADLAND remarked that the root had been describedin the Pharmaceutical Journal some time since.

Dr. ROUTH said that turpentine had been found more effica-cious than the root in question amongst the Zulu Kaffirs.

Dr. WILLSHIRE said turpentine was superior to the root un-combined, but the etherial preparations of the root were supe-rior to turpentine.

’ Mr. JOHN BIRKETT read a paper giving, PRACTICAL ILLUSTRATIONS OF THE TREATMENT OF SOME CASES

OF INJURY TO THE HANDS.

The main object of the paper was to illustrate the bad effectsl of applying adhesive plaster to wounds and injuries of the; hands, and to recommend the treatment of these cases by

the use of slips of lint, kept constantly wet by means of aninstrument called an "irrigator," placed at the head of the

i patient’s bed. Several practical illustrations of this mode of! treatment were given, it being especially advocated in everyL kind of injury of the hand or fingers, except the purely incised, wound inflicted with a sharp cutting instrument. In such,i the careful adjustment of the lips of the wound with adhesivel plaster may be admissible. In other injuries complicated with

wounds, the author’s experience induced him to recommendthe thorough cleansing of the hand by soaking in lukewarmwater, and narrow strips of linen or lint wetted in tepid water

L to be lightly applied around the injured fingers, commencing- from their ungual phalanges. When severe lacerations of the

hand or palm are present, they are to be treated by pieces oflint with a slit in them. the arm to be suDDorted and raised


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