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Cardiovascular Data Analysis ModelHL7 Balloting

(September 22, 2011)

Salvatore MungalDuke Bioinformatics Shared Resources (DBSR)Duke Cancer Institute (DCI)

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Agenda• Background:

– Stakeholders– Harmonization of the data elements

• HL7 Balloting– Converting to the RIM (RIM mapping)– HL7 Balloting

• Future Plans– Including CDISC terminology– Update model from balloting comments– Loading the CV DAM to caDSR

• Acknowledgements• Questions

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Stakeholders

• Duke Clinical Research Institute (DCRI)• American College of Cardiology (ACC)• Clinical Data Interchange Standard Consortium (CDISC)• Federal Drug Agency (FDA)• NCI CBIIT (EVS and caDSR)• HL7 (RIM) v3 messaging - (CCHIT certification for EHR)

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Harmonization of Data Elements

• Harmonization of the Data elements was coordinated by the ACC and DCRI via a governance group that consisted of practicing cardiologists

• Data was collected from all over the USA• DCRI also has international clinical studies• The focus of the harmonization effort was from the following

registries (from 23,000 hospitals across the country) using >10.5 million records (data several years old):– Cath PCI (CAD) – Action(STEMI) – ICD (Devices) – ACC top 100 data elements

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High Level View of the CV DAM

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RIM Mapping

Published with permission

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HL7 Balloting• Story Board/Use Case(s)• Activity Diagram• Data elements• EA file• Class Models• Description of Project

May 2009 Ballot sitehttp://www.hl7.org/ctl.cfm?action=ballots.home&ballot_cycle_id=520&ballot_voter_id=5082 Published with

permission

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HL7 Balloting• We needed 27 affirmative votes to pass ballot and we received 35• We received very constructive comments from several voters.  • At the HL7 working group meeting in San Diego, the team reviewed the

comments and determined they would add considerable value to the model.  

• Our team in collaboration with members of the HL7 Clinical Interoperability Council,  decided to incorporate the revisions into an updated version of the DAM and submit it as CV DAM version V2.1 for review later this fall.  

• A follow-up review or ballot cycle is customary when structural changes to the model and/or changes to the clinical content of the model are made.  

• This cycle will give all stakeholders an opportunity to review and accept the updates before the model is published as an informative standard.

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Future Plans• CDISC terminology• Loading the CV DAM to caDSR

– Currently working on Semantics • Creation of a Cardiovascular ontology

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Acknowledgements

CDISC

DBSRWilliam Barry, Director

Chris Tolk, Director Terminologies

ACCDana PinchottiArsalan KhalidGanesan Srinivasan

DCRIBrian McCourt, Assoc. DirectorDavid KongRebecca Wilgus

HL7 (CIC)Mead WalkerDianne ReevesAnita Walden

NCI CBIITSherri De Coronado, Director Semantic ServicesMargaret HaberDianne Reeves

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Q & A