12
AMI: 3.6% CHF: 5.9% Arrhythmia/cardiac arrest: 24.3% Other cardiac: 1.7% CVA: 2.3% Infection: 10.0% Withdrawal: 10.8% Malignancy: 5.0% All other: 36.3%
AMI: 4.9%CHF: 5.0%Arrhythmia/cardiac arrest 26.5%Other cardiac: 1.9%CVA: 3.3%Infection: 10.9%Withdrawal: 10.5%Malignancy: 3.7%All other: 33.4%
91 92 93 94 95 96 97 98 99 00 01 02 03 04 05 06 07 08 09 10D
eath
s pe
r 1,0
00 p
atie
nt y
ears
0
20
40
60
80
100
Complex method
Simple method
2000 2005 2010
Dea
ths
per 1
,000
pat
ient
yea
rs
0
20
40
60
80
100
12020-44 45-64 65-74 75+
2000 2005 2010
Dea
ths
per 1
,000
pat
ient
yea
rs
0
20
40
60
80
100White Black/Af Am Other
2000 2005 2010D
eath
s pe
r1,0
00 p
atie
nt y
ears
0
20
40
60
80
100Hemodialysis Peritoneal dialysis
2000 2005 2010
Dea
ths
per 1
,000
pat
ient
yea
rs
0
20
40
60
80
100Diabetes Hypertension
GN Other
Months after initiation
0 1 2 3 4 5 6 7 8 9 10 11 120.00
0.05
0.10
0.15
0.20
0.25
Sudden cardiac death
CVD
non-CVD
Death
Prob
abili
ty
Months after initiation
0 1 2 3 4 5 6 7 8 9 10 11 120.00
0.02
0.04
0.06
0.08
0.10
White
Blk/Af Am
Other
Prob
abili
ty
Months after initiation
0 1 2 3 4 5 6 7 8 9 10 11 120.00
0.02
0.04
0.06
0.08
0.10
Hemodialysis
Peritoneal dialysis
Prob
abili
ty
Months after initiation
0 1 2 3 4 5 6 7 8 9 10 11 120.00
0.03
0.06
0.09
0.12
0.15
20-44
45-64
65-74
75+
Prob
abili
ty
Months after initiation
0 1 2 3 4 5 6 7 8 9 10 11 120.00
0.02
0.04
0.06
0.08
0.10 Diabetes Hypertension GN Other
Prob
abili
ty
92 94 96 98 00 02 04 06 08 10
Bars
: Num
ber o
f pat
ient
s (in
1,0
00s)
0.0
3.0
6.0
9.0
12.0
15.0
Line
: Per
cent
of p
atie
nts
0.0
0.2
0.4
0.6
0.8
1.0
1.2
2005 2006 2007 2008 2009 2010
Bars
: Num
ber o
f pat
ient
s
0
15
30
45
60
Line
: Per
cent
of p
atie
nts
0.000
0.003
0.006
0.009
0.012
0 6 12 18 24 30 36
Surv
ival
pro
babi
lity
0.0
0.2
0.4
0.6
0.8
1.0
Primary prevention Secondary prevention
Hemodialysis
Months after ICD/CRT-D
0 6 12 18 24 30 36 0 6 12 18 24 30 36
Peritoneal dialysis Transplant
Months
0 2 4 6 8 10 12 14 16 18 20 22 24
Surv
ival
pro
babi
lity
0.0
0.2
0.4
0.6
0.8
1.0
Primary prevention
Secondary prevention
92 94 96 98 00 02 04 06 08 10
Perc
ent o
f pat
ient
s
0.0
0.2
0.4
0.6
0.8
Hemodialysis
Peritoneal dialysis
Transplant
HD PD Tx
Rate
per
1,0
00 p
atie
nt y
ears
0
10
20
30
40
50
60
70Fatal Non-fatal
HD PD Tx HD PD Tx
2000 2005 2010
Months after AMI0 3 6 9 12 15 18 21 24
Cum
ulat
ive
prob
abili
ty o
f dea
th
0.0
0.2
0.4
0.6
0.8
1.0
1993 1998 2003 2008
65+ 0-19 20-39 40-64
Cum
ulat
ive
perc
ent o
f pat
ient
s
0
5
10
15
20
25Day 90 Day 180 Day 365
65+ 0-19 20-39 40-64
Cum
ulat
ive
perc
ent o
f pat
ient
s
0
5
10
15
20Day 90 Day 180 Day 365
65+ 0-19 20-39 40-64
Cum
ulat
ive
perc
ent o
f pat
ient
s
0
10
20
30
40
50
60 Day 90 Day 180 Day 365
65+ 0-19 20-39 40-64
Cum
ulat
ive
perc
ent o
f pat
ient
s
0.00
0.05
0.10
0.15
0.20
0.25
0.30Day 90 Day 180 Day 365
0 3 6 9 12 15 18 21 24 27 30 33 36
Perc
ent o
f pat
ient
s
0
20
40
60
80
1002000 2005 2010
Prevalent dialysis First wait-listed
Months
-12 -9 -6 -3 0 3 6 9 12 15 18 21 24 27 30 33 36
0 3 6 9 12 15 18 21 24 27 30 33 36
Perc
ent o
f pat
ient
s
0
20
40
60
80
100Prevalent dialysis First wait-listed
Months
-12 -9 -6 -3 0 3 6 9 12 15 18 21 24 27 30 33 36
2000 2005 2010
0 3 6 9 12 15 18 21 24 27 30 33 36
Perc
ent o
f pat
ient
s
2000 2005 2010
0
10
20
30
40
50Prevalent dialysis First wait-listed
Months
-12 -9 -6 -3 0 3 6 9 12 15 18 21 24 27 30 33 36
0 2 4 6 8 10 12
Perc
ent o
f pat
ient
s
0.0
0.1
0.2
0.3
0.4
0.5
0.6Prevalent dialysis First wait-listed
Months
-12 -10 -8 -6 -4 -2 0 2 4 6 8 10 12
0
10
20
30
40
50
ACEI/ARBalone
ACEI/ARB &Beta blker
Beta blkeralone
Neither ACEI/ARBalone
ACEI/ARB &Beta blker
Beta blkeralone
Neither
Perc
ent o
f pat
ient
s
2007 2010
Dialysis Transplant
0 6 12 18 24 30 36
Cum
ulat
ive
inci
denc
e
0.0
0.2
0.4
0.6
0.8ACEI/ARB aloneBeta blocker aloneACEI/ARB & beta blocker No drug
Cumulative incidence of death
Months after CHF diagnosis
0 6 12 18 24 30 36
Cumulative incidence of a CVD hospitalization
0 6 12 18 24 30 36
Cum
ulat
ive
inci
denc
e
0.0
0.2
0.4
0.6
0.8
ACEI/ARB aloneBeta blocker aloneACEI/ARB & beta blocker No drug
Cumulative incidence of death
Months after AMI event
0 6 12 18 24 30 36
Cumulative incidence of a CVD hospitalization
