Catalysis and regulation

784 Catalysis and regulation Proteolysis

Catalysis and regulation

Proteolysis Related review: Proteases (pp 713 720)

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Rat G l u t a t h i o n e S -Trans fe rase - l -1 b y Q u i n o n e s a n d T h e i r G i u t a t h i o n e C o n j u g a t e s - S t r u c t u r e Act iv i ty R e l a t i o n s h i p a n d M e c h a n i s m . Biochem/ 1991, 276:661 ~*(K}

WAkSH DA, GtA~s DB, MITCHEU. RD: S u b s [ r a t e D i v e r s i t y o f t he C-AMP~lependen t P r o t e i n K l n as e : R e g u l a t i o n Based U p o n M u l t i p l e B i n d i n g I n t e r a c t i o n s . Curr Opin (Jell Bio119¢)2, 4:241 281

WASHBIIRN kVN, DENNIR EA: S u i c i d e - I n h i b i t o r y B i f u n e t l o n a l l y L i n k e d S u b s t r a t e s (SlBLINKS) as P h o s p h o l l p a s e - A 2 l n h i h i t o r s - M e c h a n i s t i c I m p l i c a t i o n s . . l Biol C&,m 1991, 266:5042 8048

WEIGEL TM, MILLER VP, lau HW: M e c h a n i s t i c a n d S t e r e o c h e m i c a l S t u d i e s o f a U n i q u e D e h y d r a t i o n Ca ta lyzed h y CDP-4-Keto-6-deoxy-D-g lucose- 3 - d e h y d r a s e - a P y r i d o x a m i n e 5 ' - P h o s p h a t e D e p e n d e n t E n z y m e I so l a t ed f r o m Yer s in i a - P s e u d o t u b e r c u l o s i s . I~l~&beml~glr}~ 1992. 31:2140 2]47

WENTE SR. SCHACIhMAN ttK: D i f f e r en t A m i n o Acid S u b s t i t u t i o n s at t h e S a m e P o s i t i o n in t he N u c l e o t i d e - B i n d i n g Si te o f A s p a r t a t e T r a n s c a r b a m o y l a s e have D i v e r s e Effects o n t h e A l lo s t e r t c P r o p e r t i e s o f t h e E n z y m e . ] Biol Ch{,m 1991, 266:2083~20839.

WI'I*I SN, MCCONNEIJ HM: A F i r s t - o r d e r R e a c t i o n C o n t r o l s t h e B i n d i n g o f A n t i g e n i c P e p t i d e s t o Majo r H i s t o c o m p a t i h i l i t y C o m p l e x Class l l Molecu le s . Prig Natl Acad Sci U ~' A 1991, 88:8164 8168.

YM)AV A, JACKSON RM, HOiaRR(X)K JJ, WAP~M[EL A: Role o f S o l v e n t R e o r g a n i z a t i o n E n e r g i e s i n t h e Cata ly t ic Act iv i ty o f E n z y m e s . J Am Chem b~x 199 I 113:480(~4805

YAMAZI !MI K, DOOIJ'Iq'IZ RF: P h o t o a f f t n i t y L a b e l i n g o f t h e P r i m a r y F i b r i n P o l y m e r i z a t i o n Si te - Loca l i z a t i on o f t h e Label to G a m m a - C h a i n Tyr- 363. t'rl*_ Natl Acad Sci U S A 1992, 89:2893 2896

YANG X, CASTLEM&N AW: C h e m i s t r y o f Large H y d r a t e d A n i o n C l u s t e r s X - ( H 2 0 ) n , O-Less-Than-or-Equal- to -n-Almos t -Equa l - to -50 a n d X - OH, O, 0 2 , a n d 0 3 . 1. R e a c t i o n o f CO2 a n d P o s s i h l e A p p l i c a t i o n i n U n d e r s t a n d i n g o f E n z y m a t i c R e a c t i o n D y n a m i c s . J Am Chem S¢~ 1991, 113:67(q) 677 I

ZBIRAL E, KLEINEIDAM RG, SCHREINER E, ]]ARTMANN M, CHRIStiAN R, SCHAUER R: E l u c i d a t i o n o f t h e T o p o l o g i c a l P a r a m e t e r s o f N - A c e t y l n e u r a m i n i c Acid a n d S o m e A n a l o g u e s I n v o l v e d i n T h e i r I n t e r a c t i o n w i t h t h e N - A c e t y l n e u r a m i n a t e Lya~se f r o m C l o s t r i d i u m - p e r f r i n g e n s . Bioct~,m l 191)2 282:511 516

ZENG J, VAIa,EE BL, KAGI JHR: Z i n c T r a n s f e r f r o m T r a n s c r i p t i o n Fac tor - I l iA F i n g e r s to T h i o n e i n C lus t e r s . Proc Natl Acad Sci U S A 1991, 88:9¢)84 998~

aILiNG B, RO7tt R& A R e g i o n o f t h e I n s u l i n R e c e p t o r I m p o r t a n t f o r L igand B i n d i n g ( r e s i d u e s 450- 601) is R e c o g n i z e d b y P a t i e n t s ' A u t o i m m u n e A n t i b o d i e s a n d I n h i b i t o r y M o n o c l o n a l A n t i b o d i e s . pr(~. Nat lAcadSt i U S A 1991. 88:98589862.

ZISMAN E, SEIA M, MOZES E: D i r e c t B i n d i n g o f a S y n t h e t i c M u l t i c h a l n P o l y p e p t i d e to Class !1 Ma jo r H i s t o c o m p a t l b i l i t y C o m p l e x M o l e c u l e s o n A n t i g e n - p r e s e n t i n g Cel l s a n d S t i m u l a t i o n o f a Speci f ic T-cel l L ine R e q u i r e P r o c e s s i n g o f t h e P o l y p e p t i d e . Fr¢x Nat~ Acad ski ~'r ,~ A 19¢)1. 88:973~9742.

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AGGEIE~R R, CHICARCRtIZ K, CM 8X, KEANA JlZ~ ', CAPAIJ)I RA I n t r o d u c t i o n o f Reac t ive C y s t e i n e R e s i d u e s i n t h e E p s i l o n - S u b u n i t o f E s c h e r i c h i a - C o l i F1 ATPase, Modi f i ca t ion o f T h e s e S i tes w i t h T e t r a f l u o r o p h e n y l A z i d e - M a l e i m i d e s , a n d E x a m i n a t i o n n f Changes i n t h e B i n d i n g o f t h e E p s i l o n - S u b u n i t w h e n D i f f e r en t N u c l e o t i d e s a r e i n Ca ta ly t ic Si tes . Bioc&,mtst O, 1992, 31:29S(> 2961

AI.IAKIWERDIEV SI, KUMOV ~%', DEMEqER S: T h e r m o l u m i n e s c e n c e E v i d en ce fo r Light - I n d u c e d O x i d a t i o n o f T y r o s i n e a n d H i s t i d i n e R e s i d u e s i l l M a n g a n e s e - D e p l e t e d P h o t o s y s t e m - l l Par t i c les . FEtI~ Lett 19¢)2, 297:51%4

AI.hltAW1 MK, SENIOR AF: Ca ta ly t ic S i tes o f E s c h e r i c h i a COIl F1-ATPase - C h a r a c t e r i z a t i o n o f U n i s i t e Ca ta lys i s at V a r i e d PH. Biochemi~trv 1992. 31:878885,

AI£ttAWI MK, SENIOR AE: Effects o f D i m e t h y i S u l f o x i d e o n Cata lys is in Esche r i ch l a -Co l i F1-ATPase. Bi{~,mistry 1992. 31:8g(> ~')1

ANDERSON J~', BHANOT P, GEORGES F, KIE~ql RIll, WAYGC'OD EB: I n v o l v e m e n t o f t h e C a r b o x y - T e r m i n a l R e s i d u e i n t h e Act ive Si te o f t h e H i s t i d i n e - C o n t a i n i n g P r o t e i n , HPr , o f t h e P h o s p h o e n o l p y r u v a t e : S u g a r P h o s p h o t r a n s f e r a s e S y s t e m o f E s e h e r i c h i a - C o l i . Biochemislry 199 l, 30:9(z01 9607.

ANDRE B, BOVER B, IANL¢]'r G, ROQUE JP: Efl~cient Ca ta ly t i c Act iv i ty o f P o l y m e r i z e d Micel le- F o r m i n g S u r f a e t a n t s . Tetrahedmm Lett 1991, 32: lgRql 1884.

ANqONNY B, CHAPA)IN P, ROUX M~ CHAI~RE M: GTP H y d r o l y s i s M e c h a n i s m s i n g a s P21 a n d i n t h e Ras-GAP C o m p l e x S t u d i e d h y F l u o r e s c e n c e M e a s u r e m e n t s o n T r y p t o p h a n M u t a n t s . lli(K'/~vmL~try 1991, 30 :8287~295

A( )YAMA Y, Y¢)RtlIDA Y: D i f f e r e n t S u b s t r a t e Spec i f i c i t i e s o f L a n o s t e r o l 1 4 - a l p h a - D e m e t h y l a s e ( P 4 5 0 ( 1 4 D M ) ) o f S a c c h a r o m y e e s - C e r e v i s i a e a n d Rat L iver F o r 24-Methy lene-24 ,25- D i h y d r o l a n o s t e r o l a n d 2 4 , 2 5 - D i h y d r o l a n o s t e r o l . Bu)cbem Bi(~t;3,s Res C?)mmun 19¢)1, 178:10('~ 107]

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BIiROZA P, FREDKIN DR, OKAMURA MY, FEHER G: P r o t o n a t l o n o f I n t e r a c t i n g R e s i d u e s i n a P r o t e i n b y a M o n t e C a r l o M e t h o d : A p p l i c a t i o n to L y s o z y m e a n d t h e P h o t s y n t h e t i c R e a c t i o n C e n t e r o f R h o d o b a e t e r S p h a e r o i d e s . I 'r~ Nat/ AcadSci I R A 19¢)1, 88:5804 5808

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JA(()B F, JORIS B, FRERE JM; Act ive-Si te S e r i n e M u t a n t s o f t h e S t r e p t o m y c e s - A l b u s , G Beta -Lac tamase . Biochem J 1991, 277:647~52.

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MASbON S, DESMOUIJN F, SCIAKy M, CO/ZONE PJ: T h e Effects o f E t h a n o l C o n c e n t r a t i o n o n Glyce ro - 3 - P h o s p h a t e A c c u m u l a t i o n i n t h e P e r f u s e d Rat L iver - a R e a s s e s s m e n t o f E t h a n o l - I n d u c e d I n h i b i t i o n o f G lyeo lya l s U s i n g P-31-NMR S p e c t r u s e o p y a n d HPLC. FurJ Bi{u:bem 1992, 205:187 194

MCINEOSH DB, WOOLLEY DG, BERMAN MC: 2 ' ,3 ' -O- 1 2 , 4 , 6 - T r i n l t r o p h e n y l ) -8-Azido-AMP a n d ATP P h o t o l a b e i L y s 4 9 2 at t h e Act ive Si te o f S a r c o p l a s m i c R e t l c o l u m Ca2 + -ATPase. J Blot C~em 1992, 267:5301 5309

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M(~X; C, I)EIOI]I.ME JC, BAt I)IER J. REVEl MO. HiS{ ttl)Fv P, tIIE~*I~R H, l,ttl B: M e m b r a n e - R e l a t e d O x y s t e r o l F u n c t i o n - P r e l i m i n a r y Resu l t s o n t he M o d i f i c a t i o n o f P r o t e i n Kinase-C Act iv i ty a n d S u b s t r a t e P h o s p h o r y l a t i o n By 7 b e t a , 2 5 - D i h y d r o x y c h o l e s t e r o l . Bio~t}imiu 19 ~) i 73:1321 1326

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MIIRRA5 IA, I~'xX~ENIX)N A, S]]AxX ' x~': S t a b i l i z a t i o n o f t h e l m i d a z o l e R i n g o f His-195 at t h e Act ive Si te o f C h l o r a m p h e n i c o l A c e t y l t r a n s f e r a s e . ! IJio/ Che,; 19")I, 266:11695 11698

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OKAMIIRA T, SANCAR A, HEEH5 PF, BI',GIJ~ TP, HIRAIA ~. MALAGA N: P i c o s e c o n d Laser P h o t o l y s i s S t u d i e s o n t h e P h o t o r e p a l r o f P y r i m i d i n e D i m e r s b y DNA P h o t o l y a s e . 1. Laser P h o t o l y s i s o f P h o t o l y a s e - 2 - D e o x y u r i d i n e D i n u c l e o t i d e P h o t o d i m e r C o m p l e x . . I Am Chem S~- 1991. 113:3143 31q5

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PALMER MAJ, DIFFERDING E, GAMBONI R, WILIa~4S SF, PEOPIJ=5 OP, WM£H CT, SINSKEY AJ, M&SAMUNE S: B i o s y n t h e t i c T h i o l a s e f r o m Z o o g l o e a - R a m i g e r a - E v i d e n c e fo r a M e c h a n i s m I n v o l v i n g Cys-378 as t b e Act ive S i t e Base, J Biol Chem 199l, 266:8369~8375

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800 Catalysis and regulation Miscellaneous

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W~HBt'RN WN, DENNIS E& Suic ide- Inhib i tory f i i funct ional ly Linked Substrates (SIBLINKS) as Phospholipase-A2 Inh ib i to r s - Mechanistic Impl ica t ions . . /Bio l CTx~m 1991, 266:~042 50q8.

X[ GY, I~EBER CM: Confo rma t ions of Neuro tens in in Solu t ion and in Membrane Env i ronment s S tudied by 2-D NMR Spectroscopy. lnl] Pept Protein Res 1991, 37:~28 ~35

Y~M~ YF, WHI~ ~ ' : Ident i f i ca t ion and Character izat ion o f the Funct iona l A m i n o Acids at the Active Center o f Pig Liver Thio i t ransferase by Site-Directed Mutagenesis . l Bfol (.~em l~)l . 266:12~5~ 12765

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Catalysis and regulation

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