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CCS CONTAINED COMPACTION S DRY GRANULATION · The Fitzpatrick Chilsonator™ is the Ideal Roll...

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Leading Particle Processing Technologies The Fitzpatrick Company CCS SERIES | CONTAINED COMPACTION SYSTEM DRY GRANULATION
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Leading Particle Processing Technologies The Fitzpatrick Company

CCS SERIES | CONTAINED COMPACTION SYSTEM DRY GRANULATION

The Fitzpatrick Chilsonator™ is the Ideal Roll Compaction System

for Dry Granulation Pharmaceutical Powders

> Improve Compact Uniformity & Density

Minimize the degree of ungranulated material to improve

downstream powder fl ow characteristics with

a unique pre-compression feed system and

precision real-time roll gap control

> Enhance Operator Safety

& Product Containment

Best-in-class containment features, including

WIP (wash-in-place) capabilities and in-wall

designs, helps achieve full containment with

minimal investment

> Minimize Maintenance

& Production Downtime

Fewer parts with easy access for teardown

and cleaning, lead to faster changeovers and a

simplifi ed parts inventory

> Accelerate Scale-Up

& Reduce Development Costs

Fitzpatrick’s application expertise, lab

capabilities, support services and scalable

equipment parameters ensures faster and

more reliable development and scalability

The CCS Roll Compaction Series from Fitzpatrick

CCS SERIES Contained Compaction System

2

| Leading Particle Processing Technologies

Innovative Compaction System

> Improves compact uniformity and densityReal-time roll gap feedback control and precision

parallel fl oating rolls

ensure a more uniform

compact for improved

downstream particle fl ow

> Enhances continuous

process stability and

scalabilityDirect roll force measurement with integrated

load cell and PID control loop allows for a more

accurate and repeatable compact density

Improve Compact Uniformity & Density

3

Independent, Two-Screw Feed Design > Eliminates the need for vacuum dearation

Independent pre-compression screw removes air from most

powders prior to the compaction process

> Reduces ungranulated bypassSeparate speed control of the pre-compression screw leads to more uniform density

and minimizes the degree of ungranulated material passing through the compaction

zone without the need for higher roll forces

Independent, vertical screw pre-compresses material prior to entering the rolls,

leading to higher material yields and more uniform compact

Bar rotor for slow-speed

“crushing” of compact

Knife rotor for “in air”

impact of harder compacts

Optimized Granulation Process

> Controls particle size distribution

and minimizes fi nesA greater degree of rotor/screen designs allows

for an optimized milling process, leading to tighter

PSD ranges

> Handles a wider range of powdersThe selection of milling options also allows for

the handling and optimization of a wide range of

applications, including even the hardest compacts

Hydraulic Force

FixedRoll

Floating

Roll

CCS SERIES Contained Compaction System

FLOOR MOUNTED

CCS 720

The CCS Series is designed to fully contain all product in the

processing and receiving sections of the machine. This tightly

sealed design allows for the optional product containment system

(PCS) to be added at the discharge.The PCS draws a slight vacuum

in the process environment to provide

maximum containment.

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Product ContainmentSystem (PCS)

> Achieves full containment with minimum initial investment

> Minimizes product exposure to operator and environment

> Prevents product contamination and product loss

> Combines with an N2 inerting system to reduce oxygen exposure and explosion risks

Enhance Operator Safety & Product Containment

| Leading Particle Processing Technologies

Optional WIP System

(Wash-in-Place)

IN-WALL

CCS 1025IN-WALL

CCS 102555

SPRAY

SPRAY

SPRAY & DISCHARGE

5

CCS SERIES Contained Compaction System

6

> Fewer parts to remove during production cycles, allowing for:

• Faster Changeover

• Faster Cleaning

• Less downtime

• Less inventory formaintenance parts

> Easy roll shell removal

> Hydraulic system spreads rolls for cleaning

> Double lip seal ensures technical area remains sealed while primary seal is removed for cleaning

> Components conveniently disassemble from the machine or can be removed as a unit for remote disassembly

> Fully automated controls

• Automatic operation of all components from the operator interface

• Fully instrumented with convenient display

• Batch reporting, historical trending and event logging

• 21 CFR part 11 capable (optional)

• Multiple levels of password security

Minimize Maintenance & Production Downtime

| Leading Particle Processing Technologies

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With our industry-leading compaction technology

and application expertise, Fitzpatrick is the ideal

partner at every stage, from preliminary analysis

to full production.

> Our lab service assists in determining if your

product is a candidate for roll compaction

> Preliminary analysis covers several variables,

including moisture tests and pressure vs. density

curves

> We offer CCS220 rental units or in-house Lab

Services to help optimize the compaction process

parameters for your powders

> The CCS220 is ideal for pilot validation and easily

scales to larger production units

> All CCS units offer the same diameter rolls,

allowing for a more reliable scale-up to a

production model, either a CCS720 or CCS1025

> Fitzpatrick offers extensive validation and

qualifi cation services

> Worldwide support ensures your process will

keep running to specifi cation

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CCS 220up to 25 Kg/hr

CCS 720up to 250 Kg/hr

CCS1025 up to 400 Kg/hr

CCS 220

CCS 720

Accelerate Scale-Up & Reduce Development Costs

MATERIAL PROCESSING

CCSGEN14

Global Presence

World Headquarters IDEX MPT Centers of Excellence

Representation In Over 80 Countries Worldwide

832 Industrial Drive Elmhurst, IL 60126TEL: 630.530.3333 | FAX: 630.530.0832 | EMAIL: [email protected] | www.fitzmill.com

Hammer Milling

Roller Compaction

Conical Milling

High Shear Mixing

High Pressure Homogenization

Cell Disruption

Lean Powder Handling

Batching, Mixing and Packing

World Headquarters

Representation In Over 80 Countries Worldwide

IDEX MPT Centers of Excellence

GLOBAL PRESENCE

Materials Processing Technologies


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