Regents Biology
BW #3
Watch the video…Write
down 3 things you
learned.
video
Regents Biology
What is homeostasis?
Let’s ask an expert!
Regents Biology
Cell Membrane
Substances move in and out of the cell in
order for the cell to function properly and
maintain homeostasis.
Homeostasis
Homeostasis -- the ability of an organism to
maintain a constant internal balance even
when the conditions around it change.
Which organelle in the cell is responsible for
maintaining homeostasis?
Regents Biology
Cell (plasma) membrane
Cells need an inside & an outside…
separate cell from its environment
cell membrane is the boundary
Regents Biology
Semi-permeable membrane
Cell membrane controls what gets in or out
Need to allow some materials — but not all — to pass through the membrane
semi-permeable only some material can get in or out
aa H2Osugar lipids salt waste
So what needs to get across the membrane?
O2
Regents Biology
Building a membrane
How do you build a barrier that keeps
the watery contents of the cell separate
from the watery environment?
What substance
do you know
that doesn’t mix
with water?
FATS
LIPIDS
Remember: oil & water don’t mix!!
Regents Biology
Lipids of cell membrane Membrane is made of special kind of lipid
phospholipids
“split personality”
Membrane is a double layer
phospholipid bilayer
lipid
“repelled by water”
“attracted to water”
phosphate
Regents Biology
Crossing the cell membrane
What molecules can get through the cell
membrane directly?
fats and oils can pass directly through
inside cell
outside cell
lipid
salt
aa H2Osugar
waste
but…
what about
other stuff?
Regents Biology
Cell membrane channels
Need to make “doors” through membrane
protein channels allow substances in & out
specific channels allow specific material in & out
H2O channel, salt channel, sugar channel, etc.
inside cell
outside cell
sugaraaH2O
saltwaste
Regents Biology
How do you build a semi-permeable
cell membrane?
Channels are made of proteins
proteins both “like” water & “like” lipids
bi-lipidmembrane
protein channelsin bi-lipid membrane
Regents Biology
Protein channels
Proteins act as doors in the membrane
channels to move specific molecules
through cell membrane
HIGH
LOW
Regents Biology
Molecules move from high to low
Diffusion
Molecules move from HIGH to LOW
concentration
EXAMPLE
Regents Biology
Concentration???
Think of it as how crowded something
is…
Which is more concentrated? WHY?
Regents Biology
Simple vs. facilitated diffusion
inside cell
outside cell
lipidinside cell
outside cell
glucose
simple diffusion facilitated diffusion
glucose
protein channel
Regents Biology
Diffusion
Move from HIGH to LOW concentration
directly through membrane
simple diffusion
no energy needed
help through a protein channel
facilitated diffusion (with help)
no energy needed HIGH
LOW
Regents Biology
Facilitated Diffusion
Move from HIGH to LOW through a channel
inside cell
outside cell
sugar
sugar
sugar
sugar
sugarsugar
sugarsugar
sugarsugar
sugar
Which way will
sugar move?
sugar
sugar
LOW
HIGH
Regents Biology
BW #4
Name 2 things about simple
diffusion, facilitated diffusion,
and osmosis that are the
same. (you may use your
notes from last class)
Regents Biology
Active transport
Cells may need molecules to move
against concentration “hill”
need to pump “uphill”
from LOW to HIGH using energy
requires energy (ATP)
Moves Through Proteins
ATP
Regents Biology
Food is moved into the cell by Endocytosis
Wastes are moved out of the cell by Exocytosis
animation
Movement through Vesicles
• Endocytosis and Exocytosis is the mechanism by which very large molecules (such as food and wastes) get into and out of the cell
• ENERGY is needed for this process to occur.
Regents Biology
NO ENERGY NEEDED: (passive transport)DiffusionOsmosisFacilitated Diffusion
ENERGY NEEDED:Active TransportEndocytosis, exocytosis
ANALOGY:
Regents Biology
Osmosis
Water is very important, so we talk about
water separately
Osmosis
diffusion of water from HIGH concentration
of water to LOW concentration of water
across a semi-permeable membrane
Regents Biology
Keeping water balance
Cell survival depends on balancing
water uptake & water loss
freshwater balanced saltwater
Regents Biology
Keeping right amount of water in cell
Hypotonic
high concentration of water outside cell
Which means water moves intothe cell and the cell swells
Example
a cell in fresh water
freshwater
No problem,here
KABOOM!
1
Regents Biology
Keeping right amount of water in cell
Hypertonic Solution
lower concentration of water outside cell
Which means water moves out of the cell and the Cell Shrinks
Example Cells in salt water
saltwater
I willsurvive!
I’m shrinking,I’m shrinking!
2
Regents Biology
Keeping right amount of water in cell
Isotonic Solutions
no difference in concentration of water between cell & environment
No change in the size of cell
How different cells handle too much or too little water
balanced
I couldbe better…
That’sbetter!
3
Regents Biology
HYPERTONIC ISOTONIC HYPOTONIC
HYPOTONIC ISOTONIC HYPERTONIC HYPOTONIC ISOTONIC HYPERTONIC
Regents Biology
Type of Transport
Definition
Energy Needed
Y/NProtein Helpers
Type of Molecule
Transported
Diffusion
(p. 72)
Molecules moving
from high to low
concentrations
NO None ANY molecule
Osmosis
(p. 73)
WATER moving
from high to low
concentrations
across a
membrane
NO*None
*AquaporinsWater
Regents Biology
Type of Transport
Definition
Energy
Needed Y/NProtein Helpers
Type of Molecule
Transported
Facilitated
Diffusion
(pg. 73-74)
Diffusion
through a
protein in the
cell membrane
No YES
Some
charged or
Large
molecules
Regents Biology
Type of Transport
Definition
Energy
Needed Y/NProtein Helpers
Type of Molecule
Transported
Active
Transport
(p. 74)
Molecules
move from
LOW to HIGH
concentrations
YES YES
*Large
Molecules
*Charged
Molecules