Session: 2016-17
1
Schemes of Examinations
&
Syllabi
of
M. Pharmacy
for
Industrial Pharmacy (Pharmaceutics)
(2016-2017)
Ch. Bansi Lal University, Bhiwani
Session: 2016-17
2
Ch. Bansi Lal University, Bhiwani
Scheme of Examination for M. Pharmacy Industrial Pharmacy (Pharmaceutics)
Semester-I Credits: 34 Marks: 750
Paper
Code
Subjects
Type
of
Course
Contact Hours Per Week Credits Examination Scheme Total
Theory Practical Total Theory Practical Total Internal
Assessment
Theory Practical
MIP-101 Modern Analytical
Techniques-I (MAT-I)
C.M.C 04 -- 04 04 -- 04 20 80 100
MIP-102 Dosage Forms Design
and Development
C.C 04 -- 04 04 -- 04 20 80 100
MIP-103 Advances in Drug
Delivery-I
C.C 04 -- 04 04 -- 04 20 80 100
MIP-104 Advanced
Pharmacokinetics and
Biopharmaceutics-I
C.C 04 -- 04 04 -- 04 20 80 100
MIP-105 Biostatistics I.D.C 04 -- 04 04 -- 04 20 80 100
MIP-106 Practical (MAT-I) C.M.C - 06 (6X1) 06 -- 03 03 -- - 100 100
MIP-107 Pharmaceutics Practical
(MIP 102- 104)
C.C - 18 (6X3) 18 -- 09 09 -- - 100 100
MIP-108 Seminar/ Journal Club C.C 03 -- 03 -- -- 01 -- -- -- 25
MIP-109 Self-study Paper C.C -- -- -- -- -- 01 -- -- -- 25
Total 23 24 47 20 12 34 100 400 200 750
C.C = Core Course I.D.C = Inter Disciplinary Course E.C= Elective Course C.M.C= Complimentary Course
Session: 2016-17
3
Scheme of Examination for M. Pharmacy Industrial Pharmacy (Pharmaceutics)
Semester-II Credits: 34 Marks: 750
Paper
Code
Subjects
Type
of
Course
Contact Hours Per Week Credits Examination Scheme Total
Theory Practical Total Theory Practical Total Internal
Assessment
Theory Practical
MIP-201 Modern Analytical
Techniques-II
(MAT-II)
C.M.C 04 -- 04 04 -- 04 20 80 100
MIP-202 Advances in Drug
Delivery-II
C.C 04 --- 04 04 04 20 80 100
MIP-203 Advanced
Pharmacokinetics and
Biopharmaceutics-II
C.C 04 -- 04 04 -- 04 20 80 100
MIP-204 Pharmaceutical
Technology and
Biotechnology
C.C 04 -- 04 04 -- 04 20 80 100
MIP-205 Intellectual Property
Rights
C.C 04 - 04 04 -- 04 20 80 - 100
MIP-206 Practical (MAT-II) C.M.C 06 (6X1) 06 -- 03 03 -- -- 100 100
MIP-207 Pharmaceutics
Practical (MIP 201-
MIP 203)
C.C -- 18 (6X3) 18 -- 09 09 -- -- 100 100
MIP-208 Seminar/ Journal Club/
Synopsis
C.C 03 - 3 - - 01 - - - 25
MIP-209 Self-study Paper
-- - -- - - 01 - - 25
Total 23 24 47 20 12 34 100 400 200 750
C.C = Core Course I.D.C = Inter Disciplinary Course E.C= Elective Course C.M.C= Complimentary Course
Session: 2016-17
4
Scheme of Examination for M. Pharmacy Industrial Pharmacy (Pharmaceutics) 3
rd Semester Credits: 23 Marks: 225
PART-I (DISSERTATION WORK)
Paper Code Subject Contact
Hours
Credits
Examination Marks Max. Marks
Internal External
MIP-301 Pharmaceutical Entrepreneurship 04 04 20 80 100
MIP-302 Midterm Evaluation/ Presentation/ Viva
voce
-- -- -- 100 100
MIP-303 Journal Club
(One Research Paper Per Student) 02 1 25 - 25
MIP-304 Research Work 36 18 - - -
Total 42 23 45 180 225
4th
Semester Credits: 23 Marks: 250
PART-II (DISSERTATION WORK)
Paper Code Subject Contact
Hours
Credits
Examination Marks Max. Marks
Internal External
MIP-401 Communication Skills 04 04 20 80 100
MIP-402 Journal Club
(One Research Paper Per Student)
02 01 25 25
MIP-403 Research Work 36 18
MIP-404 Dissertation Evaluation by External
Examiner
- - - 100 100
MIP-405 Dissertation/Final Presentation & Viva
voce
- 50 50
Total 42 23 45 230 275
Duration- 02 years (04 semesters) Total Marks- 2000
Total Credits- 114
Session: 2016-17
5
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-101
Modern Analytical Techniques -I (MAT- I)
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
UV-Visible spectroscopy: Brief review of electromagnetic spectrum, UV-Visual range, energy-
wavelength colour relationships. Interaction of electro - magnetic radiation (UV-Vis) and matter and
its effects, Chromophores and their interaction with EMR, Woodward-Fieser rule, Absorption
spectra of organic compounds and complexes illustrating the phenomenon and its utilization in
qualitative and quantitative studies of drugs, Beer-Lambert‟s law, Shifts and their interpretation
(including solvent effects). Multi component analysis, derivative spectroscopy.
Spectrofluorimerty: Fluorescence, Phosphorescence, Chemiluminescence-Theory, instrumentation
and Applications (9 Lectures)
UNIT-II
Infra-Red Spectroscopy: Nature of Infra-red radiation, Interaction of IR radiation with organic
molecules and effects on bonds, Molecular or infra-red spectra, Brief outline of classical IR
instrumentation and interpretation of spectra, including sample preparation for spectroscopy,
Qualitative interpretation of IR Spectra, Influence of substituents, ring size, hydrogen bonding
vibrational coupling and field effect on frequency, Quantitative methods, FT-NIR and applications.
Recent advances in IR Spectroscopy.
Raman spectroscopy- Principle, Instrumentation and Applications
Laser Spectroscopy: Introduction, principle, instrumentation and applications. (9 Lectures)
UNIT-III
Chromatographic Techniques: Introduction and classification
High performance TLC –Principle, adsorbents, retention and separation parameters, detection
methods, quantitative and quantitative HPTLC.
Gas Chromatography: Introduction, principles, Instrumentation, carrier gas, types of columns,
columnselection- liquid stationary phases, column efficiency parameters, the Van Deemter equation,
Resolution, Derivatisation methods, Detectors. A critical comparison of sensitivity, selectivity and
field of applications of these detectors. Applications of GC in Pharmaceutical sciences.
(9 Lectures)
Unit-IV Liquid Chromatography: Instrumentation, columns, packing materials, column selection, mobile
phase selection, efficiency parameters, resolution and optimization of chromatographic parameters.
Detectors in HPLC: Comparison of sensitivity selectivity and field of applications of these
detectors. Modes of HPLC-Ion pair, Ion-exchange, Size exclusion, Supercritical, Chiral, Gel-
permeation, Flash chromatography. Applications of liquid chromatography. UPLC
Emission Spectrometry (Atomic Absorption Spectrometry, Flame Photometry). (9 Lectures)
Session: 2016-17
6
Reference books:
1. Principles of Instrumental Analysis, 5th Ed., D.A. Skoog, F.J. Holler and T. A. Nieman.
2. "Spectrometric Identification of Organic Compounds" Silverstein, R.M., Bassler & Morril 5th
Ed., 1991.
3. Instrumental Methods of Analysis, H.H. Willard, L.L Merritt, J.A. Dean, F.A. Settle, 7th Ed.
4. Pharma Analysis, Modern Methods - (Ed) James W Munson Part-B, Vol. -2.
5. Drugs & Pharma, Sciences Series, Marcel Dekker Inc.
6. “Applications of absorption spectroscopy of organic compounds” by John R. Dyer.
7. “Contemporary practice of chromatography” by Poole, Colin F. and Sheila A. Schuette.
8. Ewing‟s Analytical Instrumentation Handbook, edited by Jack Cazes, CRC press.
9. “Practical HPLC method development” by L. R. Snyder Willey Interscience, Second Ed.
10. Aldrich FT-IR Spectral Library.
11. “Pharmaceutical Analysis” by David C. Lee Blackwell Publisher.
Session: 2016-17
7
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-106
Practical (MAT-I)
Maximum Marks: 100
Time: 06 hrs/week
1. Use of UV Vis spectrophotometer for analysis of Pharmacopoeial compounds and their
formulations.
2. Simultaneous estimation of multi component containing formulations by UV
spectrophotometry.
3. Effect of pH and solvent on UV spectrum of certain drugs.
4. Experiments on factors affecting the absorbance/fluorescence in UV spectroscopy/
Fluorimetry.
5. Interpretation of IR spectra
6. Experiments based on various chromatography techniques for separation of mixture of
compounds.
7. Any other practical based on aforementioned theory.
Reference books:
1. Principles of Instrumental Analysis, 5th Ed., D.A. Skoog, F.J. Holler and T. A. Nieman.
2. "Spectrometric Identification of Organic Compounds" Silverstein, R.M., Bassler & Morril
5th Ed., 1991.
3. Instrumental Methods of Analysis, H.H. Willard, L.L Merritt, J.A. Dean, F.A. Settle, 7th Ed.
4. Pharma Analysis, Modern Methods - (Ed) James W Munson Part-B, Vol. -2.
5. Drugs & Pharma, Sciences Series, Marcel Dekker Inc.
6. “Applications of absorption spectroscopy of organic compounds” by John R. Dyer.
7. “Contemporary practice of chromatography” by Poole, Colin F. and Sheila A. Schuette.
8. Ewing‟s Analytical Instrumentation Handbook, edited by Jack Cazes, CRC press.
9. “Practical HPLC method development” by L. R. Snyder Willey Interscience, Second Ed.
10. Aldrich FT-IR Spectral Library.
11. “Pharmaceutical Analysis” by David C. Lee Blackwell Publisher.
Session: 2016-17
8
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-102
DOSAGE FORM DESIGN AND DEVELOPMENT
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Preformulation Studies
Introduction, goals of preformulation, physicochemical properties, criteria for selection of drug and
excipients, compatibility tests.
Solid State Pharmaceutics
Crystalinity, crystal habit, polymorphism, amorphous state, solvates and hydrates and analytical
techniques for characterization.
Stability Testing
Stress testing and stability assessment protocols, photostability, packing influence on stability, New
drug summations specific stability issues and general approaches for the improvement of stability of
finished products. (9 Lectures)
UNIT-II
Solubility and Solubilisation
Development of theoretical relationships of prognostic relevance, techniques of solubilisation of
drugs including surfactant systems, co-solvents, solid state manipulations, complexation and
chemical modifications.
Partition Coefficient
Pharmaceutical significance of partition coefficient, correlation with in-vivo performance,
techniques to estimate log P values, shake flask method, choice of solvent systems,
chromatographic determination, theoretical computation using Hansch & Leo/Rekker principle,
effect of various variants like temperature, pH etc. on partition coefficient.
(9 Lectures)
UNIT-III
Complexation
Metal and organic molecular complexes, inclusion complexes with reference to cyclodextrins, types
of cyclodextrins, their pharmaceutical applications.
Rheology
Concepts of rheology, viscoelastic analysis of semisolids, applications and practice of rheology,
viscometers. (9 Lectures)
UNIT-IV
Optimization in Pharmaceutical Process and Formulations
Design of experiments- Basic terminology, Advantages, scope of experimental design in
pharmaceutical formulations with special emphasis on factorial designs and central composite
design, with suitable example. (9 Lectures)
Session: 2016-17
9
Reading Material Recommended:
1. Wells J.I. Pharmaceutical Prefomulation: The Physicochemical Properties of Drug
Substances. Ellis Horwood, Chiechester, U. K. Latest Edition.
2. Yalkowsky S.H. Techniques of Solubilisation of Drugs. Marcel Dekker, New York. Latest
Edition.
3. Doornbos C. and Hann P. Optimization Techniques in Formulation and Processing. In
Encyclopedia of Pharmaceutical Technology. Swarbrick J. and Boylan J.C. Eds., Vol. II,
Marcel Dekker, New York. 1995.
4. Lewis G.A. Optimization Methods. In Encyclopedia of Pharmaceutical Technology. Vol.
IV, Informa Healthcare, New York. 2007.
5. Swarbrick J. and Boylan J.C. Eds., Encyclopedia of Pharmaceutical Technology. Vol. I,
Marcel Dekker, New York. Latest Edition.
6. Singh B. and Ahuja A. Response Surface Optimization of Drug Delivery Systems. In
Controlled and Novel Drug Delivery Systems, Jain N.K. Ed., CBS, New Delhi. Latest
Edition.
7. Carstensen J.T. Drug Stability: Principles and Practices. Marcel Dekker, New York. Latest
Edition.
Session: 2016-17
10
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-103
ADVANCES IN DRUG DELIVERY-I
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Polymers in drug delivery Polymer classifications, biodegradable and non-biodegradable polymers and their Properties,
applications of polymers in controlled release. Smart polymers: types, classification, properties,
purpose of use with examples, biopolymers: properties, advantages and applications of biopolymers
in dosage form design.
Fundamentals of Controlled Release (CR) Drug Delivery
Rationale of sustained/controlled drug delivery; Physicochemical and biological factors influencing
design and performance of CR products, therapeutic status of CDDS. Pharmacokinetic/
pharmacodynamic basis of controlled drug delivery. (9 Lectures)
UNIT-II
Design and fabrication of Oral CR systems Strategies and design of oral controlled release delivery systems, oral systems based on dissolution,
diffusion and dissolution, ion-exchange resins, pH-independent formulations, altered density
formulations. Bucco/ mucoadhesive systems. Osmotic controlled oral drug delivery.
Parenteral CDD System
Parenteral systems, biopharmaceutic considerations, design and development. Implantable
therapeutic systems, biocompatibility of polymers and carriers; Intrauterine devices and intra
vaginal devices. (9 Lectures)
UNIT-III
Transdermal Drug Delivery System Transdermal therapeutic systems, Drug absorption through skin, permeation enhancers, basic
components of TDDS, approaches to development and evaluation; iontophoresis, sonophoresis and
electroporation. Heat assisted TDDS. (9 Lectures)
UNIT-IV
Novel ocular drug delivery systems Ocular therapeutics and constraints to effective delivery, formulation considerations to improve the
ocular bioavailibility, ocular inserts including insoluble and soluble inserts, non-corneal routes and
their use for systemic drug delivery.
Nasal drug delivery systems Advantage, factor effecting nasal drug delivery system. (9 Lectures)
Session: 2016-17
11
Reading Material Recommended:
1. Robinson J.R. and Lee VHL. Controlled Drug Delivery - Fundamentals and Applications.
Marcel Dekker, New York. Latest Edition.
2. Chien Y.W. Transdermal Controlled Systemic Medications, Marcel Dekker, New York.
Latest Edition.
3. Bruck S.D. Controlled Drug Delivery. Vol. I (Basic Concepts), CRC Press, Florida. Latest
Edition.
4. Bruck S.D. Controlled Drug Delivery. Vol. II (Clinical Applications), CRC Press, Florida.
Latest Edition.
5. Tyle P. and Ram B. Targeted Therapeutic Systems, Marcel Dekker, New York. Latest
Edition.
6. Prescott LF and Nimmo WS. Novel Drug and its Therapeutic Applications, John Wiley and
Sons. Chichester. Latest Edition.
Session: 2016-17
12
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-104
ADVANCED PHARMACOKINETICS AND BIOPHARMACEUTICS-I
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Compartmental Pharmacokinetics
Review of fundamentals, terminology, basics of kinetics following single dose administration
through instantaneous and non-instantaneous routes (like i.v. bolus, i.v. infusion, peroral) using
serum and urine levels, one and multi-compartmental kinetics, multiple dose administration,
superposition rule. (9 Lectures)
UNIT-II
Noncompartmental Pharmacokinetic Modeling Approach
Pitfalls of compartmental techniques and advantages of model-independent approaches, definition
and significance of stochastic approach, statistical moments, AUC, AUMC, determination of AUC
& AUMC using techniques like trapezoidal, logtrapezoidal, spline, and hybrid approaches, MRT
and its significance in pharmacokinetics, computation of statistical moments from plasma and urine
data, cut off error, MDT, MIT, MAT and bioavailability. (9 Lectures)
UNIT-III
Non-linear Pharmacokinetics
Definition, significance and applications with literature examples, recognition of nonlinearity,
computation of non-linear pharmacokinetic parameters (Vm, Km, AUC, etc.) from the time course
and AUC of a drug in body being eliminated by single Michaelis Menten kinetics, computation of
pharmacokinetic parameters (Vm, Km, K, AUC, etc.) from the time course of a drug being
eliminated by Michaelis Menten kinetics and by a blend of Michaelis Menten kinetics and first-
order kinetics.
Protein Binding
Theory of plasma protein binding and implications, elements of Scatchard, Klotz and Rosenthal
analyses for computation of binding parameters, experimental techniques to determine protein
binding with their merits and limitations, factors influencing protein binding, effect of binding on
drug pharmacokinetics.
(9 Lectures)
UNIT-IV
Physiologically Based Pharmacokinetic (PBPK) Models
Basic concepts of PBPK models, development of a PBPK model, limitations with respect to
classical compartmental approaches, permeation limited versus diffusion limited models,
interspecies scaling, applications.
Pharmacokinetic and Pharmacodynamic (PK/PD) Models Basic concepts of PK/PD modeling, methodology including linear, log-linear, Emax, maxsigmoidal
models, non-steady state and time-dependant models, biphasic distribution model, tolerance and
signal transduction models, biomarkers, non-linear mixed effect modeling, Naive pool approach,
hysteresis of pharmacodynamics response, applications. (9 Lectures)
Session: 2016-17
13
Reading Material Recommended:
1. Wagner JG. Fundamentals of Clinical Pharmacokinetics, Drug Intelligence Publication,
Hamilton. Latest Edition.
2. Wagner JG. Pharmacokinetics for the Pharmaceutical Scientist, Technomic, Pennsylvania.
Latest Edition.
3. Shargel L, Yu ABC and Wu-pong S. Applied Biopharmaceutics and Pharmacokinetics
McGraw- Hill Medical Publishers, New Delhi. Latest Edition.
4. Gibaldi M. and Perrier D. Pharmacokinetics. Informa Healthcare, New York. Latest Edition.
5. Gibaldi M. Biopharmaceutics and Clinical Pharmacokinetics, Lea & Febiger, Philadelphia.
Latest Edition.
6. Dressman B and Lennernas H. Oral Drug Absorption: Prediction & Assessment, Marcel
Dekker, New York. Latest Edition.
7. Garett ER and Hitz JL. Drug, Fate and Metabolism, Vol. 4, Marcel Dekker, New York.
Latest Edition.
Session: 2016-17
14
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-105
BIOSTATISTICS
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
Unit I
Probability and Descriptive Statistics Scientific notation: significant digits, rounding off, scientific
notation, Error analysis; Counting and Probability: Addition rules; Permutations; Combinations;
Inclusion-exclusion rule; Sampling with and without replacement; Conditional probability: Bayes‟
theorem; Independence; Descriptive statistics and Random variables; Measures of central tendency:
mean, median, mode; Expectation; Measures of spread: range, percentile, standard deviation;
Higher moments: kurtosis, skew, Displaying data: Histograms, stemand-leaf plots, box plots,
frequency distributions; Discrete random variables: Bernoulli, Binomial, Poisson; Geometric
distributions; Continuous random variables: Normal; Exponential distributions; Standard normal
distribution. (9 Lectures)
Unit II
Inferential statistics and one sample hypothesis testing Samples and populations: Random,
stratified and cluster sampling; Single- and Double-blind experiments; Point and interval estimates;
Sampling distributions: t, chi-square, F distributions; Hypothesis testing: null and alternative
hypotheses, decision criteria, critical values, type I and type II errors, Meaning of statistical
significance; Power of a test; One sample hypothesis testing: Normally distributed data: z, t and chi-
square tests; Binomial proportion testing. (9 Lectures)
Unit III
Multi-sample and nonparametric hypothesis testing two sample hypothesis testing; Nonparametric
methods: signed rank test, rank sum test; Kruskal-Wallis test; Analysis of variance: One-way
ANOVA. (9 Lectures)
Unit IV
Curve fitting Regression and correlation: simple linear regression; Least squares method; Analysis
of enzyme kinetic data; Michaelis-Menten; Lineweaver-Burk and the direct linear plot; Logistic
Regression; Polynomial curve fitting.
Design of Experiments Single factor experiments; Randomized block design; Lackett-Burman
Design; Comparison of k treatment means; Factorial designs; Blocking and confounding; Response
surface methodology. (9 Lectures)
Texts/References
1. Bernard Rosner, Fundamentals of Biostatistics, 5th Edition, Thomson Brooks/Cole, 2000.
2. Richard A. Johnson, Probability and Statistics for Engineers, 6th Edition, Prentice Hall,
2000.
3. Morris H. DeGroot, Mark J. Schervish, Probability and Statistics, 3rd Rev. Edition,
Addison-Wesley, 2002.
4. E. Kreyszig, Advanced Engineering Mathematics, 9th Edition, John Wiley, 2006.
Session: 2016-17
15
M. Pharmacy (Industrial Pharmacy)
Semester 1
MIP-107
PRACTICAL INDUSTRIAL PHARMACY (MIP-102-104) Maximum Marks: 100
Time: 18 hrs
Experiments in Pharmaceutics
1. Accelerated stability studies on formulations or drugs with respect to
a) Temperature dependent.
b) Effect of buffer/ pH dependent.
2. Preparation and evaluation of diclofenac sodium gels containing two different gel bases.
3. Determination of rate and order of decomposition of drugs like aspirin, acetanilide, ascorbic
acid etc (2 exp.).
4. Study of effect of various binding agents on the properties of tablets.
5. Formulation and evaluation of semi- solid dosage form using different bases and drugs of
current interest.
6. Formulation and comparative evaluation of coated and uncoated tablets (marketed) of
various categories.
7. Formulation and evaluation of stability of reconstituted dry syrups of amoxicillin or
ampicillin etc.
8. Evaluation of packaging materials.
9. Preparation and comparative evaluation with marketed products of efficiency of neutralizing
property of antacid suspensions.
10. Preparation of injectable formulation.
11. Preparation of eye drops.
12. Preparation of ear drops.
13. Product development and protocol preparation for
a) Liquid antacid preparation.
b) Multivitamin tablet/capsule.
c) Skin ointments.
d) Injection containing antibiotics.
e) Sustained release preparations.
14. Validation of sterilization.
15. Effluent treatment testing.
16. Calibration of UV.
17. Study of drug-drug/excipient interaction using DSC.
18. Study of polymorphs using DSC.
19. Experiment based on HPTLC technique.
20. Comparison of the regulatory issues of formulation and development of new formulations in
different regulatory bodies.
21. Improvement of dissolution characteristics of drugs by different methods.
22. Comparison of dissolution of different marketed products/brands.
23. Influence of polymorphism on solubility and dissolution.
24. Protein binding of drugs.
25. Calculation of bioavailability from urinary excretion data.
Session: 2016-17
16
26. Bioavailability studies of paracetamol or any other drug by salivary data.
27. Study of drug absorption through everted rat gut method-influence of different variables like
pH and drug concentration.
28. Calculation of Ka, Ke, t1/2 and Tmax from the given data.
29. Calculation of AUC and bioequivalence from the given data.
30. Preparation of albumin microspheres by heat stabilisation technique and their particle size
characterization.
31. Study on the diffusion of drugs through various polymer membranes.
32. Preparation and study on the in-vitro dissolution of various sustained action products and
comparison with marketed products.
33. Preparation of resealed erythrocytes from blood, loading of various drugs and study on the
release pattern.
34. Preparation of matrix tablets using various polymers like PVP etc. and studying their release
pattern.
35. Preparation and evaluation of microcapsules by different microencapsulation techniques
like:
a) Simple coacervation technique: Gelatin-Water-Ethanol.
b) Coacervation by temperature change: Ethylcellulose in cyclohexane for
phenobarbitone.
c) Coacervation by nonsolvent addition: Cellulose acetate butyrate in methyl ethyl
ketone using isopropyl ether as nonsolvent. (1 exp. in each)
36. Preparation and evaluation of wax embedded microspheres of diclofenac sodium and
theophylline.
37. Preparation and evaluation of reservoir type devices (e.g.) PEG, ethylcellulose in
chloroform/dichloromethane as the coating material and the drugs like salicylic acid and
caffeine.
38. Preparation of polymer film containing different drugs and studying the film characteristics
and release patterns.
39. Preparation and evaluation of albumin microspheres
40. Preparation and evaluation of microcapsules by different microencapsulation techniques
41. Preparation and evaluation of matrix tablets using various polymers
42. Study of diffusion of drugs through various polymeric membranes
43. Preparation and in vitro evaluation of buccal mucoadhesives
44. Preparation and evaluation of transdermal films
45. Preparation and evaluation of hydrodynamically balanced tablets
46. Study of in vitro dissolution of various sustained release formulations of marketed products
Session: 2016-17
17
M. Pharmacy (Industrial Pharmacy)
Semester 2
MIP-201
Modern Analytical Techniques-II (MAT-II)
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Nuclear Magnetic Resonance Spectroscopy: Fundamental principles of NMR (Magnetic
Properties of nuclei, applied field and precession, absorption and transition frequency). Chemical
shift concept, Isotopic nuclei, Reference standards, proton magnetic spectra, their characteristics,
presentation, terms used in describing spectra and their interpretation (signal no., position,
intensity), Brief outline of instrumental arrangements and some practical details, Signal multiplicity
phenomena in high resolution PMR, Spin-spin coupling, Application of Signal Splitting and
coupling constant data to interpretation of spectra, Decoupling and shift reagent methods.
Quantitative NMR. Brief outline of principles of 13
C NMR. Introduction to 2-D NMR Techniques.
Applications of NMR technique in Pharmaceutical sciences. (9 Lectures)
UNIT-II
Mass Spectrometry: Basic principles and brief outline of instrumentation. Ion formation and types,
molecularion, meta stable ions, fragmentation processes, Fragmentation patterns and fragment
characteristics in relation to parent structure and functional groups, Relative abundances of isotopes
and their contribution to characteristic peaks, Mass spectrum, its characteristics, presentation and
interpretation, Chemical ionisation mass spectrometry, ESI, Ion-trap. FAB mass spectroscopy.
Applications of mass spectrometry. (9 Lectures)
UNIT-III
X-Ray Diffraction Methods: Elementary crystallography, X-Ray diffraction, Bragg‟s law, X-Ray
powder diffraction, X-Ray powder diffractometer- interpretation of data.
Thermal Analysis: Principles and applications of thermogravimetric analysis (TGA), Differential
thermal analysis (DTA) and Differential scanning Calorimetry (DSC). (9 Lectures)
Unit-IV
Electrophoresis: Principle, techniques, instrumentation including detection strategies and
applications
Hyphenated techniques: Brief introduction (LC-MS, GC-MS, GC-IR, LC-NMR and GC-NMR)
and applications.
Radioimmunoassay Assay and ELISA: Principle, instrumentation and applications. (9 Lectures)
Session: 2016-17
18
Reference books:
1. Principles of Instrumental Analysis, 5th Ed., D.A. Skoog, F.J. Holler and T. A. Nieman.
2. "Spectrometric Identification of Organic Compounds" Silverstein, R.M., Bassler & Morril 5th
Ed., 1991.
3. Instrumental Methods of Analysis, H.H. Willard, L.L Merritt, J.A. Dean, F.A. Settle, 7th Ed.
4. Pharma Analysis, Modern Methods - (Ed) James W Munson Part-B, Vol -2.
5. Drugs &Pharma, Sciences Series, Marcel Dekker Inc.
6. “Applications of absorption spectroscopy of organic compounds” by John R. Dyer.
7. “Contemporary practice of chromatography” by Poole, Colin F. and Sheila A. Schuette.
8. Ewing‟s Analytical Instrumentation Handbook, edited by Jack Cazes, CRC press.
9. “Practical HPLC method development” by L. R. Snyder Willey Interscience, Second Ed.
10. Aldrich FT-IR Spectral Library.
11. “Pharmaceutical Analysis” by David C. Lee Blackwell Publisher.
Session: 2016-17
19
M. Pharmacy (Industrial Pharmacy)
Semester 2
MIP-207
Practical (MAT-II)
Maximum Marks: 100
Time: 06 hrs/week
1. Interpretation of NMR and Mass spectra.
2. Experiments Based on flame photometry.
3. Any other practical based on aforementioned theory.
Reference books:
1. Principles of Instrumental Analysis, 5th Ed., D.A. Skoog, F.J. Holler and T. A. Nieman.
2. "Spectrometric Identification of Organic Compounds" Silverstein, R.M., Bassler & Morril
5th Ed., 1991.
3. Instrumental Methods of Analysis, H.H. Willard, L.L Merritt, J.A. Dean, F.A. Settle, 7th Ed.
4. Pharma Analysis, Modern Methods - (Ed) James W Munson Part-B, Vol -2.
5. Drugs &Pharma, Sciences Series, Marcel Dekker Inc.
6. “Applications of absorption spectroscopy of organic compounds” by John R. Dyer.
7. “Contemporary practice of chromatography” by Poole, Colin F. and Sheila A. Schuette.
8. Ewing‟s Analytical Instrumentation Handbook, edited by Jack Cazes, CRC press.
9. “Practical HPLC method development” by L. R. Snyder Willey Interscience, Second Ed.
10. Aldrich FT-IR Spectral Library.
11. “Pharmaceutical Analysis” by David C. Lee Blackwell Publisher.
Session: 2016-17
20
M. Pharmacy Industrial Pharmacy (Pharmaceutics)
Semester 2
MIP-202
ADVANCES IN DRUG DELIVERY –II
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Colloidal and supramolecular delivery systems -I:
Closed bi-layered system: Historical background, structural aspects, preparation, characterization,
evaluation and applications of liposomes, specialized liposomes like Pharmacosomes and
Niosomes.
Nanoparticles and microspheres: Method of preparation, characterization, evaluation and
pharmaceutical applications. (9 Lectures)
UNIT-II Multiple w/o/w emulsions as drug vehicles, composition of the multiple emulsion and stability,
influence of the nature of oily phase, methods for stabilizing w/o/w multiple emulsions.
(9 Lectures)
UNIT-III
Colloidal and supramolecular delivery systems -II
Microemulsions: Introduction, structure of microemulsions, solubilization and formulation of
microemulsions, Self-emulsifying drug delivery systems (SEDDS), transport properties and
pharmaceutical applications of emulsions. (9 Lectures)
UNIT-IV
Protein and peptide drug delivery Considerations in the physiological delivery of therapeutic proteins; carrier-mediated transport of
peptides and peptide analogues, problems associated with the delivery of protein and peptides.
Targeted drug delivery History, concept, types and key elements; ideal carrier system and approach with special reference
to organ targeting (e.g. brain, tumor, lung, liver and lymphatics); Basics of temperature, pH and
magnetically induced targeting. (9 Lectures)
Reading Material Recommended:
1. Robinson JR and Lee VHL. Controlled Drug Delivery - Fundamentals and Applications.
Marcel Dekker, New York. Latest Edition.
2. Bruck SD. Controlled Drug Delivery. Vol. I (Basic Concepts), CRC Press, Florida. Latest
Edition.
3. Bruck SD. Controlled Drug Delivery. Vol. II (Clinical Applications), CRC Press, Florida.
Latest Edition.
4. Tyle P and Ram B. Targeted Therapeutic Systems, Marcel Dekker, New York. Latest Edition.
5. Vyas SP and Khar RK. Targeted and Controlled Drug Delivery. CBS, New Delhi. Latest
Edition.
6. Jain NK. Advances in Controlled and Novel Drug Delivery. CBS, New Delhi. Latest Edition.
Session: 2016-17
21
M. Pharmacy (Industrial Pharmacy)
Semester 2
MIP-203
ADVANCED PHARMACOKINETICS AND BIOPHARMACEUTICS-II
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Clinical Pharmacokinetics
Introduction, pharmacokinetic relationships, duration of response, kinetics of pharmacological
response, explanation of clinical response via pharmacokinetics, monitoring plasma concentrations
of drugs during clinical use including problems encountered in clinical investigations, analysis of
clinical relevance of kinetic studies, turnover concepts, individualization of dosage and dosage
regimen, variability, genetics, age, weight, disease, interacting drugs, use of creatinine clearance,
problem solving. (9 Lectures)
UNIT-II
Biopharmaceutics
Review of physicochemical, pharmaceutical and physiological variables affecting absorption.
Bioavailability and bioequivalence concepts, assessment of bioavailability from serum and urine
level data, crossover design and analysis of bioequivalence trials, biowaivers, federal perspectives,
problem solving. (9 Lectures)
UNIT-III
In vitro and In vivo of correlations (IVIVC)
Concept, biopharmaceutical classification scheme, various IVIVC approaches with applications and
limitations, dissolution as a surrogate to bioavailability for immediate release and extended release
formulations, A-D levels, validation, IVIVR, IVIVM, federal perspectives.
Pharmacokinetic Simulations and Allied Pharmacokinetic Approaches
Pharmacokinetic simulations using pharmacokinetic parameters, simple problem solving. Basics of
chronopharmacokinetics, toxicokinetics, population pharmacokinetics. (9 Lectures)
UNIT-IV
Use of Computers in Pharmacokinetics
Introduction, strategy for model building, selection and application of suitable pharmacokinetic,
statistical and variance models, function minimization for maximization of goodness of fit, iterative
and non-iterative techniques, weighting schemes for non-linear regression, AIC, SC, MSC, digital
versus analog computers, law of parsimony, literature review on computer software on
compartmental, noncompartmental and clinical pharmacokinetic analysis and simulation, and
biopharmaceutics. (9 Lectures)
Session: 2016-17
22
Reading Material Recommended:
1. Wagner JG. Fundamentals of Clinical Pharmacokinetics, Drug Intelligence Publication,
Hamilton. Latest Edition.
2. Wagner JG. Pharmacokinetics for the Pharmaceutical Scientist, Technomic, Pennsylvania.
Latest Edition.
3. Shargel L, Yu ABC and Wu-pong S. Applied Biopharmaceutics and Pharmacokinetics
McGraw-Hill Medical Publishers, New Delhi. Latest Edition.
4. Gibaldi M and Perrier D. Pharmacokinetics. Informa Healthcare, New York. Latest Edition.
5. Gibaldi M. Biopharmaceutics and Clinical Pharmacokinetics, Lea & Febiger, Philadelphia.
Latest Edition.
6. Dressman B and Lennernas H. Oral Drug Absorption: Prediction & Assessment, Marcel
Dekker, New York. Latest Edition.
7. Bourne DEA. Mathematical Modelling of Pharmacokinetic Data. Technomic, Pennsylvania.
Latest Edition.
8. Welling PG and Tse FLS. Pharmacokinetics: Regulatory, Industrial and Academic
Perspectives, Marcel Dekker, New York. Latest Edition.
9. Gibaldi M and Prescott L. Handbooks of Clinical Pharmacokinetics, ADIS, New York.
Latest Edition.
10. Rowland M and Tozer TN. Clinical Pharmacokinetics: Concepts and Applications,
Lippincott Williams & Wilkins. New York. Latest Edition.
Session: 2016-17
23
M. Pharmacy (Industrial Pharmacy)
Semester 2
MIP-204
PHARMACEUTICAL TECHNOLOGY AND BIOTECHNOLOGY
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Pharmaceutical Technology
Tablet production systems: Benefits, production, process design considerations, materials handling,
processing step combination and elimination, unit operation improvement, tablet production
equipments.
Tablet production: Layout of facilities, materials flow, quality assurance procedures, design of
facilities, construction considerations, equipment consideration, environmental consideration,
materials management and inventory control. (9 Lectures)
UNIT-II
Processing of small volume parenterals (SVP‟s) and related sterile products: Planning and
scheduling, material and personnel management, documentation control. Facilities - AHU's,
humidity and temperature controls, air filtration systems, dust collectors. Manufacturing including
various aspects of preparing SVP solutions, suspensions, powders/freeze dried powders for
reconstitution, filling, sealing, inspection and labelling.
Manufacture of LVP‟s: Raw materials including water, stability, storage and inventory control,
batch mixing, clarification by membrane filters and support systems. (9 Lectures)
UNIT-III
GMP of Pharmaceuticals : Current GMP in manufacturing, processing, packaging of drugs. GMP
for finished products. General provision, organization and personnel, building and facilities,
equipment, control of components and drug product, container and closures, production and
process, packaging and labeling, laboratory and control of records and reports.
Pharmaceutical Process Validation : Basic concept, definition and regulatory basis of validation.
Benefits of validation. Phases of quipment validation such as pre-purchase,post-purchase (IQ,OQ
and PQ) and qualification of established /in-use equipment. Types of process validation.
Retrospective, Prospective, Concurrent Validation, Validation of tablets and sterile products.
Validation of steam, dry heat, gaseous, radiation and filtration sterilization processes. Analytical
Validation. (9 Lectures)
UNIT-IV
Recombinant DNA technology: Types of genetic recombination, genetic transformation,
transduction, plasmids and their biological significance, conjugation, transposons, various cloning
vectors including plasmids and bacteriophages, host for cloning vectors, expression vectors,
practical applications of genetic recombination.
Monoclonal antibodies: Production of monoclonal antibodies, diagnostic therapeutic and analytical
applications. An introduction to their role in drug targeting.
Gene Therapy: An introduction to genetic disorders, approaches used, viral and non-viral mediated
gene therapy, safety and ethical considerations. (9 Lectures)
Session: 2016-17
24
Reading Material Recommended:
1. Lieberman HA and Lachman L. Pharmaceutical Dosage Forms: Tablets. Vol. I, II and III,
Marcel Dekker, New York. Latest Editions.
2. Avis KE, Lachman L and Lieberman HA, Pharmaceutical Dosage Forms: Parenterals.
Volume I and II, Marcel Dekker, New York. Latest Edition.
3. Prescott LM, Harley JP and Klein DA. Microbiology. Wm. C. Brown Publishers, England.
Latest Edition.
4. Vyas SP and Dixit VK. Pharmaceutical Biotechnology. CBS, New Delhi. Latest Edition.
5. Remington JP, Science and Practice of Pharmacy. Lippincot Williams and Wilkins, New
York. Latest Edition.
Session: 2016-17
25
M. Pharmacy (Industrial Pharmacy)
Semester 2
MIP-205
INTELLECTUAL PROPERTY RIGHTS Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Intellectual Property Rights
Concepts and fundamentals: The emergence and growth of the concepts regarding intellectual
property (IP), intellectual property protection (IPP) and intellectual property rights (IPR); economic
importance, copyright, trademarks; role of IP in pharmaceutical industry; global ramifications and
financial implications.
Ethical issues in IPR/IPP (9 Lectures)
UNIT-II
Trade Related Aspects of Intellectual Property Rights
Intellectual property and international trade, concept behind WTO, WIPO, GATT, TRIPs, TRIMS
and GATS, status in India and other developing countries. (9 Lectures)
UNIT-III
Indian Patent Act. 1970 and its amendements: WTO and modifications under TRIPS, filing of a
patent application, precautions before patenting-disclosures/non-disclosures, publication-
article/thesis, prior art search – published patents search, internet search, patent sites, specialized
service search requests, costs, patent application forms and guidelines, fee structure, time frames,
jurisdiction aspects. (9 Lectures)
UNIT-IV
Technology Development/Transfer Commercialization Related Aspects Technology
developmentTypes of patent applications provisional, non-provisional, PCT and convention patent
applications, international patenting requirement procedures and costs. Patent infringement:
Meaning, scope, litigation, drug related patents infringements, case studies and examples, patenting
by research students. (9 Lectures)
Reading Material Recommended
1. Treece DJ. Managing Intellectual Capital: Organizational, Strategic and Policy Dimension.
Oxford University Press, England. Latest Edition.
2. Wadedhra BL. Law Relating to Patents, Trademarks, Copyright Design and Geographical
Indications. Universal Law Publishing, New Delhi. Latest Edition.
3. Bansal P. IPR Handbook for Pharma Students and Researchers, Pharma Book Syndicate,
Hyderabad. Latest Edition.
4. Copyright Protection in India [website: http:copyright.gov.in].
5. Information on Orange Book [website: www.fda.gov/cder/ob/default.htm].
Session: 2016-17
26
M. Pharmacy (Industrial Pharmacy)
Semester 2
MIP-207 (MIP 202-204)
PRACTICAL INDUSTRIAL PHARMACY (PHARMACEUTICS)
Maximum Marks: 100
Time: 18 hrs
Formulation, Development and Optimization
1. Preformulation studies of various drugs and dosage forms.
2. Accelerated stability studies of drug and its formulations.
3. Practicals related to calculation of Shelf life and overages.
4. Practicals relating to specialized formulations.
5. In-vitro dissolution studies of drugs and dosage forms.
6. Practicals relating to statistical optimization of dosage forms.
Advances in Biopharmaceutics and Pharmacokinetics
1. Calculations related to Fundamentals of zero-order and first-order pharmacokinetics
2. Determination of various pharmacokinetics parameters from Plasma concentration time data for
One compartment and Multi compartment model for intravenous and extra venous
administrations.
3. Determinations of Pharmacokinetics parameters from Urinary Excretion Data
4. Calculations related to Non-Linear Pharmacokinetics
5. Dose Adjustment calculations in clinical pharmacokinetics
6. Demonstration of various pharmacokinetic softwares.
7. In-vivo pharmacokineic study on animal.
8. Preparation and evaluation of albumin microspheres
9. Preparation and evaluation of microcapsules by different microencapsulation techniques
10. Preparation and evaluation of matrix tablets using various polymers
11. Study of diffusion of drugs through various polymeric membranes
12. Preparation and in vitro evaluation of buccal mucoadhesives
13. Preparation and evaluation of transdermal films
14. Preparation and evaluation of hydrodynamically balanced tablets
15. Study of in vitro dissolution of various sustained release formulations of marketed products
Session: 2016-17
27
M. Pharmacy (Industrial Pharmacy)
Semester 3
MIP-301
PHARMACEUTICAL ENTREPRENEURSHIP
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
UNIT-I
Accounting and Finance
Taking decision on starting a venture; Assessment of feasibility of a given venture/new venture;
Approach a bank for a loan; Sources of financial assistance; Making a business proposal/Plan for
seeking loans from financial institution and Banks; Funds from bank for capital expenditure and for
working; Statutory and legal requirements for starting a company/venture; Budget planning and
cash flow management; Basics in accounting practices: concepts of balance sheet, P&L account,
and double entry bookkeeping; Estimation of income, expenditure, profit, income tax etc.
UNIT-II
Marketing
Assessment of market demand for potential product(s) of interest; Market conditions, segments;
Prediction of market changes; Identifying needs of customers including gaps in the market,
packaging the product; Market linkages, branding issues; Developing distribution channels;
Pricing/Policies/Competition; Promotion/ Advertising; Services Marketing
UNIT-III
Negotiations/Strategy With financiers, bankers etc.; With government/law enforcement authorities; With
companies/Institutions for technology transfer; Dispute resolution skills; External
environment/changes; Crisis/ Avoiding/Managing; Broader vision–Global thinking
Information Technology How to use IT for business administration; Use of IT in improving business performance; Available
software for better financial management; E-business setup, management.
UNIT-IV
Human Resource Development (HRD) Leadership skills; Managerial skills; Organization structure, pros & cons of different structures;
Team building, teamwork; Appraisal; Rewards in small scale set up.
Fundamentals of Entrepreneurship Support mechanism for entrepreneurship in India
Role of knowledge centre and R&D Knowledge centres like universities and research institutions; Role of technology and upgradation;
Assessment of scale of development of Technology; Managing Technology Transfer; Regulations
for transfer of foreign technologies; Technology transfer agencies.
Session: 2016-17
28
Case Study 1. Candidates should be made to start a „mock paper company‟, systematically following all
the procedures.
• The market analysis developed by them will be used to choose the product or services.
SEMESTER - IV 25 M.Sc (General Biotechnology)
• A product or service is created in paper and positioned in the market. As a product or
services available only in paper to be sold in the market through the existing links. At this
juncture, the pricing of the product or the service needs to be finalized, linking the
distribution system until the product or services reaches the end consumer.
• Candidates who have developed such product or service could present the same as a
project work to the Panel of Experts, including representatives from industry sector. If the
presented product or service is found to have real potential, the candidates would be exposed
to the next level of actual implementation of the project.
2. Go to any venture capital website (like sequoiacap.com) and prepare a proposal for funding
from
SUGGESTED READINGS:
1. Dynamics of Entrepreneurial Development & Management, Vasant Desai – Himalaya
Publishing House
2. Entrepreneurship Development –Poornima M. Charantimath – Small Business Enterprises –
Pearson Education – 2006 (2 & 4)
3. Entrepreneurship Development – S. S. Khanka – S. Chand & Co
Session: 2016-17
29
M. Pharmacy (Industrial Pharmacy)
Semester 4
MIP-401
COMMUNICATION SKILLS
Maximum Marks: 100
Theory Examination: 80
Internal Assessment: 20
Time: 3 hrs
Note: There shall be nine questions in all. Question no. 1 shall be compulsory, consisting of
eight short answer type questions covering the entire syllabus. Two questions will be asked
from each unit. Student will have to attempt one question from each unit. Each question shall
carry equal marks.
Unit-I Human Communication (Theoretical perspective): Its uniqueness, its nature, models of
communication, Types of Human communication, Language, non-verbal communication, logic and
reasoning, lateral thinking. The concept of facilitating: factors, barriers and filters in
communication; the seven C‟s of effective communication. Preparing for interviews, CV/Biodata.
(9 Lectures)
Unit -II
Self-communication, interpersonal communication, dyadic communication, small group
communication. Public communication. Mass Communication. Reliability of communication. Input
and Evaluation Processes (Practice): Listening (process, comprehension, evaluation). Reading
(process, comprehension, evaluation). Watching (process, comprehension, evaluation). Email Do‟s
and Don‟ts. (9 Lectures)
Unit-III Output and Interaction Processes (Practice): Speech (conversation, interview, group discussion,
public speech). Writing (spontaneous writing, guided writing, creative writing). Organizing ideas
(noting, summary, flow charts, concept maps). Correspondence (personal, business). (9 Lectures)
Unit-IV Science/ Scientific Writing (Theory and practice): Goals and Objectives. Ethics in writing. Structure
of documents. Language and grammar. Illustrations and aids. Writing proposals and instructions.
Making presentations. Formatting documents. Drafts and revisions. Editing. Writing popular
science/ journal article. (9 Lectures)
Suggested Texts and References:
1. Communicating a social and career focus, K. M. Berko, Andrew D. Wolvyn and Darlyn R.
2. Wolvyn, Houghton Mifflin Co., Boston (1977)
3. The Craft of Scientific Writing (3rd Edition), Michael Alley, Springer, New York (1996)
4. Science and Technical Writing – A Manual of Style (2nd Edition), Philip Reubens (General
editor), Routledge, New York (2001)
5. Writing Remedies – Practical Exercises for Technical Writing Edmond H. Weiss, Universities
Press (India) Ltd., Hyderabad (2000)
6. Effective Technical Communication, M. Ashraf Rizvi, Tata Mc Graw – Hill Publishing Co. Ltd.,
New Delhi (2005)