Date post: | 28-Dec-2015 |
Category: |
Documents |
Upload: | derick-ward |
View: | 217 times |
Download: | 0 times |
Changes of Presenile Cataracts Changes of Presenile Cataracts that had been Operated over 10 years that had been Operated over 10 years
in Korea in Korea
Sung Kun Chung, M.D. ; Eun-Jung Jun, M.D. Sung Kun Chung, M.D. ; Eun-Jung Jun, M.D. Hyun Seung Kim.Hyun Seung Kim.
Department of Ophthalmology and Visual Department of Ophthalmology and Visual Science, Science, The Catholic University of KoreaThe Catholic University of Korea
No author has any financial or proprietary No author has any financial or proprietary interest in any materials or methods mentionedinterest in any materials or methods mentioned
IntroductionIntroduction Many studies about senile cataractMany studies about senile cataract
: aged more than 60 years old: aged more than 60 years old
: age is one of the most important risk factors of cataract: age is one of the most important risk factors of cataract
Presenile cataract patients may display different Presenile cataract patients may display different characteristics from senile cataract patientscharacteristics from senile cataract patients
PurposePurpose To investigate the long-term characteristics To investigate the long-term characteristics
and changes of presenile cataracts that had and changes of presenile cataracts that had been operated in Korea.been operated in Korea.
Materials & MethodsMaterials & Methods
Inclusion criteria Inclusion criteria
① ① aged from 30 to 50 years aged from 30 to 50 years
② ② underwent cataract surgeries underwent cataract surgeries at St. Mary’s hospital at St. Mary’s hospital from 1995 to 2004(n=976) from 1995 to 2004(n=976)
Exclusion criteriaExclusion criteria
① ① patients with histories of ocular patients with histories of ocular trauma or uveitis trauma or uveitis
② ② those received combined surgeries those received combined surgeries
Retrospective review of Retrospective review of medical recordsmedical records
AnalyzeAnalyze
① ① age & sex : 31-40, 41-50 groupage & sex : 31-40, 41-50 group
② ② their histories of diabetes and their histories of diabetes and hypertension hypertension
③ ③ types of lens opacities types of lens opacities
④ ④ preoperative and preoperative and postoperative visual acuities postoperative visual acuities
•Lens opacity grading : LOCSⅢLens opacity grading : LOCSⅢ (Lens Opacity Classification System III)(Lens Opacity Classification System III)
• Statistical analysis Statistical analysis : Cochran-Armitage proportion trend test: Cochran-Armitage proportion trend test
ResultsResults
30-39 years 40-49years Total
Mean age 36.2 45.3 41.7
Male 299(38.8%) 472(61.2%) 771(79.0%)
Female 81(39.5%) 124(60.5%) 205(21.0%)
History of diabetes 20(20.0) 78(80.0) 98(10.0%)
History of
hypertension
16(21.1%) 60(78.9%) 76(7.8%)
ResultsResults
Anterior polar
Opacity
Posterior subcapsular opacity
(PSCO)
Anterior polar opacity +PSCO
Cortical opacity
Nuclearopacity
30-39years
n(%)
147(42.2%)
104(30.3%)
34(50%)
12(20.3%)
16(30.2%)
40-49years
n(%)
201(57.8%)
239(69.7%)
34(50%)
47(79.7%)
37(69.8%)
Totaln
(%)348
(35.7%)343
(35.1%)68
(7.0%)59
(6.0%)53
(5.4%)
Lens opacities in each age group (LOCSⅢ)
Region of study
Sample size, race
Methods of evaluation
Age Group(yrs)
Prevalence(%) Prevalence(%)Cortical Nuclear PSC Male Female
Beijing,China
4439,Chinese
slit-lamp c AREDS
≥ 40 0.3 82.2 4.3 No statistically significantdifference in gender
Shih-Pai,Taiwan
1361,Chinese
Slit-lampc LOCSⅢ
≥ 65 21.9 38.9 9.2 Femalepredominance
Singapore
1717,Chinese
Slit-lampc LOCSⅢ
40-79 23.9 22.6 7.0 No statistically significant difference in gender
Sumatra,Indonesia
919,Indonesian
Slit-lampc LOCSⅢ
≥ 21 4 5.7 Femalepredominanceexcept cortical cat.
Victoria,Australia
4433,Australian
Slit-lampc WCGS
≥ 40 11.3 12.6 4.08 Femalepredominance
Korea 976,Korean
Slit-lampc LOCSⅢ
30-49 6.0 5.4 35.1 Male predominance
ResultsResults
*PSC : posterior subcapsular*c : with*AREDS : Age-related Eye disease Study*LOCSⅢ : Lens Opacities Classification System Ⅲ*cat. : cataract*JCCESG : Japanese Cooperative Cataract Epidemiology Study Group*WCGS : Wilmer cataract grading scheme
ResultsResults
Eyes that had surgeries for presenile cataracts displayed Eyes that had surgeries for presenile cataracts displayed
statistically significant decrease(p = 0.0002, CI 95%)statistically significant decrease(p = 0.0002, CI 95%)
Presenile cataracts with diabetes showed no significant Presenile cataracts with diabetes showed no significant
trend with the passage of time(p = 0.4767, CI 95%) trend with the passage of time(p = 0.4767, CI 95%)
Presenile cataracts with hypertension showed Presenile cataracts with hypertension showed
statistically significant increase (p = 0.0049, CI 95%) statistically significant increase (p = 0.0049, CI 95%)
ConclusionConclusion
Presenile cataract patients had different Presenile cataract patients had different
characteristics from senile cataract patients. characteristics from senile cataract patients.
Men consisted of the majority of the presenile cataract Men consisted of the majority of the presenile cataract
patients. patients.
Anterior polar opacity was the most common type of Anterior polar opacity was the most common type of
lens opacity. lens opacity.
Cataracts with hypertension showed overall increase Cataracts with hypertension showed overall increase
over 10 years.over 10 years.