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CHEM4630BIOCHEMISTRYOFPROTEINSThecourseoutlineisavailableat:h6p://home.cc.umanitoba.ca/~joneil/CHEM4630.Course.outline.htmSomethemesintheBiochemistryofProteins:1. ProteinsareBIGorganicmolecules.Thephysical-chemicalproperKesoftheaminoacidsandthepep,debondexplain• thephysical-chemicalproperKesofproteinswhichexplain• theBIOLOGICALproperKesandfuncKonsofproteins.
2.Athemeofstructuralbiologyis:
DeterminesStructureFuncKon
TheannualnumberofmolecularstructuresdepositedintheBrookhavenProteinDataBankaregraphedtotheright.
h6p://www.rcsb.org/pdb/staKsKcs/contentGrowthChart.do?content=total&seqid=100
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3.AmajorareaofresearchishowproteinstructureexpressesfuncKonthroughproteindynamics.e.g.TheenzymeFoF1ATPsynthaseusesenergystoredinaprotongradienttosynthesizeATPfromADPandPi.TheconformaKonalchangethatreleasesATPisthespinningofacentral“rotor”relaKvetotherestoftheprotein.Intheabsenceofaprotongradienttheproteindynamicsis“stochas,c”(unpredictable)butinthepresenceofaprotongradientdirec@onalrotaKonoccursowingtoprotonaKonofachargedglutamicacidside-chain.
ThemoKonwasobserveddirectlybya6achingafluorescentacKnfilamenttotheprotein:h6ps://www.youtube.com/watch?v=QeHCAFKaWM8
ThefollowingmoviesoftheproteinmoKonarebasedoninterpolaKonofX-raydiffracKonstructuresusingflip-bookoranimaKontechniques:h6ps://www.youtube.com/watch?v=J8lhPt6V-yM4.TheoutstandingquesKonsinproteinchemistrycanbegleanedfromtheKtlesoftalksgivenatinternaKonalconferences.
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American Peptide Symposium
2015
1/4/16, 12:44 PMAPS 2015
Page 1 of 2http://aps2015.org/
Our Sponsors
Disney Discounts
Save time and money by purchasingDisney tickets at a discount throughour special Disney Microsite! Disneyis offering exclusive afternoon After2PM and After 4 PM tickets, as wellas a 10% savings on all multi-day,2+ day, tickets for attendees andguests. All Multi-day tickets includean additional complimentary "BonusVisit" admission.
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VISIT DISNEY!
Welcome to the American Peptide Society's 24th International
Symposium
Symposium Venue — Orlando, Florida
We extend to you a warm Orlando welcome to the 24th AmericanPeptide Symposium. A couple of years ago, we were asked toorganize the 24th Meeting of the American Peptide Society. Initially,
this seemed like a daunting task but we were keen to take on the challenge!This unique opportunity to host the peptide community for 6 days ofstimulating science was too hard to resist, despite the amount of work weneeded to invest in this project.
In our quest to understand the best possible mix of topics to appeal to thewidest audience from Academia to Industry, we found the answer: we wantedthe enabling aspects of peptide science to come through in the strongestpossible way. The meeting theme — Enabling Peptide Research from BasicScience to Drug Discovery — embraces the spirit of the scientific and socialprograms we have assembled for you.
Recently, the use of peptides as drugs has been increasing exponentially,especially in metabolic diseases and in exploring intracellular targets. A pre-Symposium, with a theme of peptides in metabolic diseases, is planned withan emphasis on basic pharmacology and peptide targets. This is followed bya number of regular scientific sessions, which focus on topics as diverse asmacrocycles, synthetic peptides, medicinal chemistry and peptidetherapeutics, all representing emerging peptide technologies.
The scientific program for 2015 opens with distinguished lecture by Dr.Richard A. Lerner (http://aps2015.org/program/lectures_opening.html) of TheScripps Research Institute followed by a social gathering at the Upper PoolDeck of the resort. The symposium will be concluded with a lecture by Dr.Jeffrey Friedman (http://aps2015.org/program/lectures_closing.html) of theRockefeller Institute, which will be followed by the closing banquet.
Unlike previous events, two workshops will be conducted at this meeting: (1)workshop on peptide Chemistry Manufacturing and Controls (CMC) andregulatory challenges; and (2) workshop on career development, job searchstrategy and interview preparation. The lectures from awards winners,including the Merrifield, Vincent du Vigneaud, Makineni, and GoodmanAwards are spread out over the six days of the symposium.
Ved Srivastava, Ph.D.(mailto:[email protected]=Message%20from%20APS%20Website)GlaxoSmithKline, Symposium Co-Chair
Andrei Yudin, Ph.D.(mailto:[email protected]?Subject=Message%20from%20APS%20Website),University of Toronto, SymposiumCo-Chair
!
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read more +(http://aps2015.orlandomeetinginfo.com/)
read more +(travel/our_hotel.html)
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JOIN US FOR THE 24TH APS SYMPOSIUM
AMERICAN PEPTIDE SYMPOSIUM
JUNE 20-25 2015
ORLANDO, FLORIDA
.
1/4/16, 12:46 PMAPS 2015
Page 1 of 1http://aps2015.org/program/sci_topics.html
Our Sponsors
(http://www.bachem.com/)
Scientific Topics
Poster and Oral Presentations will Cover the Following Topics:
Symposium Sessions topics
Peptides in Metabolic DiseaseSynthetic methodsMacrocyclesPeptide biomaterialsBioactive peptidesPeptide structure and functionProteomics and EpigeneticPeptide catalysisCell Penetrating PeptidesPeptide medicinal chemistryMetabolism - ADMEPeptide therapeuticsPeptides in the clinicPeptide formulation and deliveryEmerging Peptide TechnologiesImmunotherapy
Stay Connected
Contact Us
Email: [email protected] (mailto:[email protected])
2014 © American Peptide Society(../index.html)
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.PepTalk
2016
1/4/16, 12:34 PMPeptalk - The Protein Science Week
Page 1 of 2http://www.chi-peptalk.com/
Recombinant Protein Therapeutics
Enhancing Antibody Binding and Specificity
Membrane Proteins
Emerging Technologies for AntibodyDiscovery and Engineering
Next-Generation Cancer Immunotherapies
Antibody-Drug Conjugates
Bispecific Antibody Therapeutics
Optimizing Biologics FormulationDevelopment
Lyophilization and Emerging DryingTechnologies
Protein Aggregation and EmergingAnalytical Tools
Engineering Genes, Vectors, Constructs andClones
Recombinant Protein Expression
Membrane Proteins
CHO Cell Culture
Applying Expression Platforms
Characterization of Biotherapeutics
Detection and Characterization ofParticulates and Impurities
Extractables and Leachables
Single-Use Technologies and ContinuousProcessing
Protein Purification and Recovery
Membrane Proteins
Higher-Throughput Protein Purification
PepTalk: The Protein Science Week is one of the largestgatherings of protein science researchers in the world. It offers anarray of education, innovation and networking programs, andprovides many opportunities to scientists.
PepTalk is an annual gathering where industry experts from aroundthe world convene to share case studies, unpublished data,breakthroughs and solutions that support and enhance research,and to gain new perspectives on the evolution of biologics.
Event Features Include:
Network with over 1200 attendees from over 30 countriesHear unpublished data and case studies from industry leadersCreate your own agenda – Premium Package allows access toall conferences for one price!Showcase your research by presenting a scientific posterParticipate in the popular BuzZ Session Roundtable DiscussionsView over 150 scientific postersBuild your own schedule using the event mobile appVisit over 100 companies in the exhibit hallTake advantage of student fellowships available for gradstudents and Ph.D. candidates
Download 2016 Brochure
Download Conference At A Glance
Premier Sponsors:
View All Sponsors
View Media Partners
View 2016 Participant list
#PTK16Agenda Sponsor/Exhibitor Downloads Travel CD/DVD Posters Press Register
<><>
.Annual World
Protein and Peptide Conference
2016
1/4/16, 12:32 PMBIT's 9th Annual World Protein & Peptide Conference
Page 1 of 4http://www.bitcongress.com/pepcon2016/ScientificProgram.asp
Scientific Program
BIT’s 9th
Annnual World Protein & Peptide Conference -2016Theme: Translation, Health and Happiness
Time: April 25-28, 2016Venue: International Conference Center, Dalian, China
Scientific Program
KeynoteForum Symposium 1 Symposium 2 Symposium 3 Symposium 4 Symposium 5 Symposium 6 YIF
Keynote Forum of PepCon-2016
Day 1: Afternoon, Tuesday, April 26, 2016
13:30-16:35
Moderator: Dr. Matthew He, Assistant Dean, Full Professor, Nova Southeastern University, USA
Time FaceOn Speeches and Speakers Org. Logo
Home About Conference Program Participant Registration Sponsorship & Exhibition Media Optional Tour
1/4/16
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International Union for
Biochemistry and Molecular Biology
2015
1/4/16, 12:37 PMIUBMB 2015 | SBBq - Confirmed Speakers
Page 1 of 4http://www.sbbq.org.br/iubmb2015/?page_id=676
Search
HomeScientific Program »Young Scientist »Registration »Congress Information »Participant Guidelines »Exhibition and SponsorshipSponsorsSatellite MeetingSpecial ActivitiesAbstract BookFeedbackSBBq Award
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Confirmed SpeakersKeynote Lecturers (confirmed):
Bruce Alberts, University of California, San Francisco, USAGünther Meister, University of Regensburg, GermanyJohann Deisenhofer, University of Texas Southwestern Medical Center, USAJose Onuchic, Rice University, USAKurt Wüthrich, The Scripps Research Institute, USAMartin Chalfie, Columbia University, USATom Steitz, Howard Hughes Medical Institue, USASalvador Moncada, The University of Manchester, UK
Symposia Speakers (confirmed):
Abel Santamaria, Universidad Autonoma Del Mexico, MXAdi Kimchi, Weizmann Institute of Science, IsraelAkihiko Nakano, University of Tokyo, JapanAlejandro Buschiazzo, Institut Pasteur de Montevideo, UruguayAlexandra Newton, University of California, San Diego, USAAmira Klip, University of Toronto, Ontario, CanadaAnamaria Camargo Aranha, Instituto Ludwig, BrazilAndrea Thompson Da Poian, Universidade Federal do Rio de Janeiro, BrazilAndrea Cristina Paula Lima, Universidad de Chile, ChileAndy Weyrich, University of Utah, USAAnthony J. Kettle, University of Otago, New ZealandBeatriz Alvarez, Universidad de La Republica, UruguayBonnie Wallace, Instiute of Structural and Molecular Biology, Birkbeck College, University of London, UKBianca Zingales, Universidade de São Paulo, BrazilByron Caughney, NIH-NIAID, USABruce Alberts, University of California, San Francisco, USACarol Prives, Columbia University, USACelso Caruzo Neves, Universidade do Rio de Janeiro, BrazilChunlin Long, College of Life and Environmental Sciences, Minzu University of China, ChinaClaudio J. Soto, University of Texas, USADario S. Zamboni, Faculdade de Medicina, USP-RP, BrazilDavid Carling, Imperial College of London, UKDebora Foguel, Universidade do Rio de Janeiro, BrazilDeborah Kurrasch, University of Alberta, CanadaDeborah Schechtman, Universidade de São Paulo, BrazilDiogo Onofre de Souza, Universidade Federal do Rio Grande do Sul, BrazilDmitry Korzhnev, University of Connecticut Health Center, USAEhud Gazit, Tel Aviv University, IsraelEduardo Galembeck, Universidade Estadual de Campinas, BrazilEfstathios S. Gonos, National Hellenic Research Foundation, GreeceElena N. Elpidina, M.V. Lomonosov Moscow State University, MoscowEric Lam, Rutgers, the State University of New Jersey, USAEnrico Gratton, University of California – Irvine, USAEtelvino J.H. Bechara, Universidade de São Paulo, BrazilFabio C.L. Almeida, Universidade Federal do Rio de Janeiro, BrazilFernanda de Felice, Universidade Federal do Rio de Janeiro, BrazilFernando Goldbaum, Fundación Instituto Leloir, ArgentinaFrancisco Ambrósio, Universidade de Coimbra, PortugalFrancisco José BARRANTES, University of Argentina-CONICETFrancisco Laurindo, Universidade de São Paulo, BrazilFred Robert Tabita, The Ohio State University, USA
The Event
1/4/16, 2:48 PMCSHL Meetings
Page 1 of 2https://meetings.cshl.edu/meetingshome.aspx
All Cancer Cell/Mol Bio 'Omics Neuro Genetics Immun/Infect
Meetings & Conferences
Meeting Name Meeting Dates Abstracts Due
Systems Biology: Global Regulation of Gene Expression Tue Mar 15 - Sat Mar 19 2016 Fri Jan 8 2016
Evolutionary Biology of Caenorhabditis & Other Nematodes Wed Mar 30 - Sat Apr 2 2016 Fri Jan 15 2016
Neuronal Circuits Wed Apr 6 - Sat Apr 9 2016 Fri Jan 22 2016
The PARP Family & ADP-ribosylation Wed Apr 13 - Sat Apr 16 2016 Fri Jan 29 2016
Protein Homeostasis in Health & Disease Mon Apr 18 - Fri Apr 22 2016 Fri Jan 29 2016
Gene Expression & Signaling in the Immune System Tue Apr 26 - Sat Apr 30 2016 Fri Feb 5 2016
Nuclear Organization & Function Tue May 3 - Sat May 7 2016 Fri Feb 12 2016
The Biology of Genomes Tue May 10 - Sat May 14 2016 Fri Feb 19 2016
The Cell Cycle Tue May 17 - Sat May 21 2016 Fri Feb 26 2016
Retroviruses Mon May 23 - Sat May 28 2016 Fri Mar 4 2016
81st Cold Spring Harbor Symposium: Targeting Cancer Wed Jun 1 - Mon Jun 6 2016 Fri Mar 11 2016
Glia in Health & Disease Thu Jul 21 - Mon Jul 25 2016 Fri May 6 2016
Genome Engineering: The CRISPR/Cas Revolution Wed Aug 17 - Sat Aug 20 2016 Fri May 27 2016
Regulatory & Non-Coding RNAs Tue Aug 23 - Sat Aug 27 2016 Fri Jun 3 2016
The PI3K-mTOR-PTEN Network in Health & Disease Tue Aug 30 - Sat Sep 3 2016 Fri Jun 10 2016
Translational Control Tue Sep 6 - Sat Sep 10 2016 Fri Jun 17 2016
Epigenetics & Chromatin Tue Sep 13 - Sat Sep 17 2016 Fri Jun 24 2016
Home Meetings Courses
Cold Spring Harbor Symposium
2016
1/4/16
6
.
1/4/16, 2:48 PMCSHL Meetings
Page 2 of 2https://meetings.cshl.edu/meetingshome.aspx
Epigenetics & Chromatin Tue Sep 13 - Sat Sep 17 2016 Fri Jun 24 2016
Axon Guidance, Synapse Formation & Regeneration Tue Sep 20 - Sat Sep 24 2016 Fri Jul 1 2016
Mechanisms of Aging Mon Sep 26 - Fri Sep 30 2016 Mon Jul 25 2016
Germ Cells Tue Oct 4 - Sat Oct 8 2016 Fri Jul 15 2016
Thirty Years of HIV/AIDS Research: The Science & Beyond Wed Oct 12 - Sat Oct 15 2016 Thu Sep 1 2016
Biological Data Science Tue Oct 25 - Sat Oct 29 2016 Fri Aug 12 2016
Neurodegenerative Diseases: Biology & Therapeutics Wed Nov 30 - Sat Dec 3 2016 Fri Sep 16 2016
Blood Brain Barrier Wed Dec 7 - Sat Dec 10 2016 Fri Sep 23 2016
Cold Spring Harbor LaboratoryMeetings & Courses Program
PO Box 100, 1 Bungtown RoadCold Spring Harbor, NY 11724-2213
Phone (516) 367-8346Fax: (516) 367-8845
1/4/16, 12:25 PMThe Protein Society: The home for the international protein science community
Page 1 of 3http://www.proteinsociety.org/meetings/symposium/
JOIN EMAIL LIST | MEMBERS ACCESS PROTEIN SCIENCE HERE:
A GLOBAL COMMUNITY OFRESEARCHERS DEDICATED TO THEUNDERSTANDING OF PROTEINS
2016 SYMPOSIUM
THE 30TH ANNIVERSARY SYMPOSIUM OFTHE PROTEIN SOCIETY
Baltimore, Maryland USA | July 16-19, 2016 | Hyatt Regency Baltimore
Topics
Birth, Life, & Death of Proteins
Protein Evolution & Design
Protein Folding & Misfolding
Emerging Methods for Protein Research
Membrane Protein Folding & Function
Proteins on the Move
Applied Protein Research
Dynamic Modulation of Protein Function
Interface Between Proteins & Nucleic Acids
Interdisciplinary Approaches to Protein Science
2016 Program Planning Committee
Brenda Schulman, St. Jude Children’s Research Hospital
Andreas Plückthun, University of Zurich
Ralf Langen, University of Southern California
Nieng Yan, Tsinghua University
2016 Confirmed Speakers
Anna Marie Pyle, Yale UniversityAndrzej Joachimiak, University of ChicagoBeili Wu, The Scripps Research InstituteBil Clemons, California Institute of TechnologyCliff Brangwynne, Princeton UniversityDan Tawfik, Weizmann Institute of ScienceDavid Eisenberg, University of California, LosAngelesEmmanuelle Charpentier, Molecular InfectionMedicine Sweden
AWARDS CRITERIA
ABOUT MEETINGS MEMBERSHIP AWARDS THE JOURNAL RESOURCES GET INVOLVED
30th Anniversary Symposium of The
Protein Society 2016
1/4/16
7
1/4/16, 12:27 PMGordon Research Conferences - Meeting List: 2016
Page 1 of 29https://www.grc.org/meetings.aspx?year=2016
Alert for GRC Attendees: GRC has received reports of a phone scam which is targeting conference attendees.Click here for more information. X
Gordon Research Conferences
Meeting List: 2016
The following meetings are currently scheduled for 2016. The meeting list can be sorted by conference name, type (GRC orGRS), date, or location, by clicking on the corresponding column heading. The list can also be narrowed down in differentways by selecting one of the tabs below. Click on a meeting name to view more details, including the current program (ifavailable).
All Meetings By Category By Site By Date By Keyword By Discipline
Display only New Meetings Hide meetings that have taken place
Display only Gordon Research Seminars
Displaying: 325 of 325 Total Meetings
Type Conference Name Dates Conference Site
Advanced Health InformaticsThe Use of Big Data in Health Related Research
Jul 17-22 The ChineseUniversity of HongKong
Advanced Materials for Sustainable Infrastructure DevelopmentThe Science and Technology of Sustainable Concrete
Jul 31 - Aug 5 The Hong KongUniversity ofScience andTechnology
Alcohol & the Nervous SystemBreakthroughs in Alcohol Neuroscience Research at the Level ofMolecules, Cells, Synapses, and Behavior
Feb 7-12 Hotel Galvez
AngiotensinAngiotensin: From Cell Biology and Signaling Networks to NovelPhysiological Paradigms and Therapeutics
Feb 21-26 RenaissanceTuscany Il Ciocco
Angiotensin (GRS)The Renin Angiotensin System in Health and Disease: LatestAdvances and New Technologies
Feb 20-21 RenaissanceTuscany Il Ciocco
Antibody Biology & Engineering Mar 20-25 Hotel Galvez
Gordon Research Conferences
2016
Diffrac@onMethodsinStructuralBiology(GRS)ProteinFuncKoninTimeandSpace:InsightsfromDiffracKonExperiments
IntrinsicallyDisorderedProteinsDisorderedProteins:FromMechanismstoTherapeuKcOpportuniKes
LipoproteinMetabolismLipidandLipoproteinMetabolisminChronicDiseasePathogenesisandTreatment
MembraneTransportProteinsMembraneTransporters:TranslaKngMoleculestoMedicine
Phosphoryla@on&G-ProteinMediatedSignalingNetworksNewDruggableTargetsUnderlyingStructuralandSpaKalAspectsofSignalinginMetabolic,Inflammatory,andOtherStress-RelatedDiseasePathways
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ProteinFoldingDynamicsFolding:TheLandscapesofNaturalandSyntheKcLife
ProteinProcessing,Trafficking&Secre@onSecretoryandEndocyKcPathwaysinHealthandDisease
ProteinTransportAcrossCellMembranesProteinTransportAcrossCellMembranes:Mechanism,Structure,andRegulaKon
Enzymes,Coenzymes&MetabolicPathwaysAdvancesinEnzymologyfromDeterminingEnzymeFuncKontotheInterplayofLargeEnzymeSystems
IntermediateFilaments(GRS)BreakingBarriersinIntermediateFilamentBiology:FromStructuretoMechanismsandTargetsinHumanDiseases
IonChannelsMolecularBasisforElectricalSignalingintheNervousSystemandBeyond
LigandRecogni@on&MolecularGa@ngMolecularBasisofLigandRecogniKonandGaKnginTransmembraneSignalingandTransport
Muscle&MolecularMotorsMotorMechanismsfromSingleMoleculestoCellularFuncKon
NotchSignalinginDevelopment,Regenera@on&DiseaseNotchSignaling:PhenotypestoMolecularMechanisms
NOXFamilyNADPHOxidasesNOXMolecularInsightsLeadingtoTranslaKon
Pep@des,Chemistry&BiologyofCrossingBarriersbyPepKdeScienceforHealthandWellness
1/4/16
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Thiol-BasedRedoxRegula@on&Signaling(GRS)RedoxBiologyinDiseasesofAging:FundamentalMechanismsandTherapeuKcPotenKal
ThreeDimensionalElectronMicroscopyAdvancingandReshapingStructuralBiologywithElectronCryo-Microscopy
1/4/16, 12:28 PMGordon Research Conferences - 2016 Meeting - Protein Folding Dynamics
Page 1 of 5https://www.grc.org/programs.aspx?id=13060
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Gordon Research Conferences
Meeting Details
Protein Folding DynamicsGordon Research Conference
Folding: The Landscapes of Natural and Synthetic Life
Dates
January 10-15, 2016
Location
Hotel GalvezGalveston, TX
Organizers
Chair: Peter G. Wolynes
Vice Chair: Benjamin Schuler
Application Deadline
The application deadline for this meeting was December 13, 2015. You may still submit an application, which may beconsidered by the conference chair if there is still room available.
Meeting Description
The protein folding problem has long been regarded as a fundamental mystery blocking our understanding of how the geneticinformation locked in DNA is transformed into a dynamic living organism. In the last decades, however, a basic understandingof the folding process has been achieved. The keys to this progress include borrowing theoretical ideas about energylandscapes from condensed matter physics and physical chemistry, employing powerful computer simulation techniques andbringing to bear new experimental tools such as single molecule methods and ultrafast spectroscopy, as well as elaboratingthe classical kinetic techniques of biophysical chemistry while exploiting the capabilities of protein engineering. Thus manycommunities from physics, chemistry and biology have merged to form the discipline of protein folding dynamics. Many of thefundamental issues about how proteins fold remain under intense investigation. New frontiers include understanding thediversity and basic time scales of folding larger proteins building on what has been learned in small model systems. Also wecan now enquire how folding behavior has evolved in natural history, using huge quantities of genomic data. Folding is nowknown to be an emergent property. Recognizing this, to test our understanding, the community is now also exploring whetherfolding can be instantiated in completely novel designed systems, so-called "foldamers". Folding is not just a preliminary stepto biological function but is intimately involved in functional processes such as allosteric change and molecular recognition.Furthermore the evolution of these capabilities has shown its mark on protein folding dynamics, an area of great fermentbringing together a new group of biologists. The misfolding of some proteins seems central to the progress of many diseasessuch as Alzheimer's and here the new tools of the folding community are bringing new insights. Finally we now can askwhether the hard won paradigms of protein folding dynamics gleaned from studying small globular proteins can be applied tomembrane protein folding in which other biological actors are implicated as chaperones. Also can folding concepts be applied
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1/4/16, 12:28 PMGordon Research Conferences - 2016 Meeting - Protein Folding Dynamics
Page 2 of 5https://www.grc.org/programs.aspx?id=13060
to studying how the very largest structures in the cell are organized, such as chromosomes? Sessions covering both newdevelopments in the basic areas as well as applications of folding dynamics to more complex biology are planned.
Contributors
Meeting Program
Sunday
4:00 pm - 8:00 pm Arrival and Check-in
6:00 pm Dinner
7:30 pm - 7:40 pm Welcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pm Keynote Session: The Atomistic Basis of Folding Energy Landscapes
Discussion Leader: Angel Garcia (Los Alamos National Laboratory, USA)
7:40 pm - 8:25 pm Robert Best (National Institutes of Health, USA)"Molecular Origins of Internal Friction in Protein Folding Dynamics"
8:25 pm - 8:35 pm Discussion
8:35 pm - 9:20 pm Klaus Schulten (University of Illinois, USA)"What Can Be Learnt from the Molecular Dynamics View of Protein Translocation, Folding andAggregation?"
9:20 pm - 9:30 pm Discussion
Monday
7:30 am - 8:30 am Breakfast
8:30 am Group Photo
9:00 am - 12:30 pm The Rights and Wrongs of Folding
Discussion Leader: Jose Onuchic (Rice University, USA)
9:00 am - 9:45 am Sheena Radford (University of Leeds, United Kingdom)"Stopping the Amyloid Cascade: New Molecular Insights and Some New Opportunities"
9:45 am - 10:00 am Discussion
10:00 am - 10:30 am Coffee Break
10:30 am - 11:15 am Paul Whitford (Northeastern University, USA)"The Role of Disorder in Biomolecular Assemblies"
11:15 am - 11:30 am Discussion
1/4/16, 12:28 PMGordon Research Conferences - 2016 Meeting - Protein Folding Dynamics
Page 3 of 5https://www.grc.org/programs.aspx?id=13060
11:30 am - 12:15 pm Susan Marqusee (University of California, Berkeley, USA)"Touring the Landscape: The View Depends on How You Look"
12:15 pm - 12:30 pm Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:30 pm - 9:30 pm Fast Folding
Discussion Leader: Martin Gruebele (University of Illinois at Urbana-Champaign, USA)
7:30 pm - 8:15 pm Gerhard Hummer (Max Planck Institute of Biophysics, Germany)"Fast Folding: Mechanisms from Simulations"
8:15 pm - 8:30 pm Discussion
8:30 pm - 9:15 pm Victor Munoz (University of California, Merced, USA)"Gradual Disorder of Fast Folding Proteins Monitored at Atomic Resolution"
9:15 pm - 9:30 pm Discussion
Tuesday
7:30 am - 8:30 am Breakfast
9:00 am - 12:30 pm Folding the Chromosome
Discussion Leader: Bin Zhang (Rice University, USA)
9:00 am - 9:45 am Andrew Belmont (University of Illinois, USA)"Boundary Conditions for Chromosome Folding Models from Direct Visualization of Native andReconstituted Chromosomes"
9:45 am - 10:00 am Discussion
10:00 am - 10:30 am Coffee Break
10:30 am - 11:15 am Erez Lieberman Aiden (Baylor College of Medicine, USA)"How the Genome Folds: Now Inside the Loop"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Masaki Sasai (Nagoya University, Japan)"Fluctuating Three-Dimensional Genome Architecture and Gene Regulation"
12:15 pm - 12:30 pm Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:30 pm - 9:30 pm Towards Synthetic Life: The World of Foldamers
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1/4/16, 12:28 PMGordon Research Conferences - 2016 Meeting - Protein Folding Dynamics
Page 4 of 5https://www.grc.org/programs.aspx?id=13060
Discussion Leader: Jeffrey Hartgerink (Rice University, USA)
7:30 pm - 8:15 pm Samuel Gellman (University of Wisconsin-Madison, USA)"Higher Order Structure in Peptidic Foldamers"
8:15 pm - 8:30 pm Discussion
8:30 pm - 9:15 pm Ivan Huc (Université de Bordeaux / CNRS, France)"Designing Foldamers with Predictable Structures"
9:15 pm - 9:30 pm Discussion
Wednesday
7:30 am - 8:30 am Breakfast
9:00 am - 12:30 pm Folding One Molecule at a Time
Discussion Leader: William Eaton (National Institute of Diabetes and Digestive and KidneyDiseases, NIH, USA)
9:00 am - 9:45 am Jane Clarke (University of Cambridge, United Kingdom)"Folding Proteins On and Off the Ribosome"
9:45 am - 10:00 am Discussion
10:00 am - 10:30 am Coffee Break
10:30 am - 11:15 am Ashok Deniz (The Scripps Research Institute, USA)"Single-Molecule Folding Biophysics of Disordered Proteins"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Michael Woodside (University of Alberta, Canada)"Observing Transition Paths in the Folding of Proteins and Nucleic Acids with Single-Molecule ForceSpectroscopy"
12:15 pm - 12:30 pm Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:00 pm - 7:30 pm Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site andScheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm Folding Membrane Proteins
Discussion Leader: Daniel Otzen (Aarhus University, Denmark)
7:30 pm - 8:15 pm Paula Booth (King's College London, United Kingdom)"Helical Membrane Proteins and Lipid Bilayer Mechanics"
8:15 pm - 8:30 pm Discussion
8:30 pm - 9:15 pm James Bowie (University of California, Los Angeles, USA)
1/4/16, 12:28 PMGordon Research Conferences - 2016 Meeting - Protein Folding Dynamics
Page 5 of 5https://www.grc.org/programs.aspx?id=13060
"Folding Membrane Proteins One at a Time"
9:15 pm - 9:30 pm Discussion
Thursday
7:30 am - 8:30 am Breakfast
9:00 am - 12:30 pm Misfolding Landscapes
Discussion Leader: Yaakov Levy (Weizmann Institute of Science, Israel)
9:00 am - 9:45 am Tuomas Knowles (University of Cambridge, United Kingdom)"Kinetics of Protein Aggregations"
9:45 am - 10:00 am Discussion
10:00 am - 10:30 am Coffee Break
10:30 am - 11:15 am Pernilla Wittung-Stafshede (Chalmers University of Technology, Sweden)"In Vitro Protein Cross-Reactivity: Links Between Parkinson's, Bacteria and Diabetes?"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Martin Zanni (University of Wisconsin-Madison, USA)"Humans but Not Rats? Cats but Not Dogs? A Study into the Molecular Mechanism of Type 2Diabetes Using 2D IR Spectroscopy"
12:15 pm - 12:30 pm Discussion
12:30 pm Lunch
1:30 pm - 4:00 pm Free Time
4:00 pm - 6:00 pm Poster Session
6:00 pm Dinner
7:30 pm - 9:30 pm Frustration and the Evolution of the Folding Landscape
Discussion Leader: Elizabeth Komives (University of California, San Diego, USA)
7:30 pm - 8:15 pm Faruck Morcos (University of Texas at Dallas, USA)"Investigating Co-Evolutionary Landscapes of Interaction Specificity in Signaling Proteins"
8:15 pm - 8:30 pm Discussion
8:30 pm - 9:15 pm Diego Ferreiro (University of Buenos Aires, Argentina)"Frustration and the Energy Landscapes of Repeat- Proteins"
9:15 pm - 9:30 pm Discussion
Friday
7:30 am - 8:30 am Breakfast
9:00 am Departure
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Miami 2016 Winter SymposiumInflammation
January 24—27, 2016 | Hyatt Regency Miami, USA
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Sessions
Acute Inflammation
Cardiovascular and Metabolic Inflammation
Neuroinflammation
Cancer and Inflammation
Resolution of Inflammation
Inflammation has remained during evolution for a good reason: it helps combating pathogens, opposingtissue injury, and healing wounds. However, in some scenarios, inflammation cannot resolve and exertsdetrimental effects on human health. The list of tissues and systems adversely affected by inflammation
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Nature: Miami Winter Symposium
2016
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continues to lengthen and includes the nervous system, the vasculature, metabolism, and tumors.
This Symposium leads off with a session on acute inflammation and its resolution or development into chronicinflammation. Subsequent sessions focus on the impact of inflammation on cardiovascular metabolism,nervous system, and cancer. A final session is centered on the pharmacological control of inflammationresolution.
Other conferences are focused on a single inflammatory condition (one tissue, one organ): at variance withthis, this Symposium program brings together experts that will discuss side by side different typesof inflammation with different technical approaches and competences.
This Symposium will be therefore of interest to a wide range of scientists: immunologists, neuroscientists,those working on diseases including diabetes, cancer, autoimmunity, neurological disorders, stroke andatherosclerosis.
Many biotechnology and pharmaceutical companies are developing therapies to interfere withproinflammatory cytokines and their receptors and/or with cytokine signaling pathways. Some speakers fromthese companies will be present to describe how basic science can develop into translational results.
Miami 2017 Winter Symposium
Sunday 22nd – Wednesday 25th January 2017
Diabetes: Today’s Research – Tomorrow’s Therapies
Conference Speakers
David Artis, USA
Glen Barber, USA
Ajay Chawla, USA
Vishwa Dixit, USA
Christopher Glass, USA
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5.Proteomics:Thestudyofglobalproteinexpressionpa6ernsthatdefinecellsinspecificbiologicalstates.-omeisanounsuffixfromtheLaKnomameaningmass.Itmayinvolvethestudyofalltheproteinsinanorganelle,cell,Kssue,ororganism.Itmayincludeotheraspectsofproteinanalysisincludingstructure,dynamics,locaKon,acKvity,funcKon,drugbinding,interacKons,regulaKonetc.6.GenomeSequencinghasdiscoveredthemolecularbasisofthemorethan1000humangeneKcdiseases.e.g.CysKcFibrosis,MuscularDystrophy,Parkinson’sDisease,Toure6e’sSyndrome……..
Whatabouttheproteinswhicharetheproductsofthosegenes?Tounderstandthediseasesandcurethemrequiresadetailedunderstandingoftheproteinsandtheirstructures.ThemostspectacularadvancetodatehasbeenthedevelopmentofAspproteaseinhibitorsusefulinsuppressingHIV-1.Thedrugsweredesignedusingthe3DstructureofAspprotease.7.Howdoproteinsfoldintotheirbiologically-acKve3Dstructures?Herearesomeexamplesofproteinfoldingdiseases:
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