CLEMSON UNIVERSITY COLLEGE OF AGRICULTURE, FORESTRY AND LIFE SCIENCES RESUME SUSAN CAROLINE CHAPMAN DATE June 2016 PERSONAL DATA Associate Professor Department of Biological Sciences Clemson University 132 Long Hall Clemson, SC 29634 864 650 1684 Phone 864 656 0435 Fax EDUCATION 2002 Ph.D. Developmental Neurobiology, King’s College London, University of London, UK, 1999 B.Sc. Science, Open University, Milton Keynes, UK 1998 B.Sc. Neuroscience, University College London, University of London, UK PROFESSIONAL EXPERIENCE 2012 - present Clemson University, Associate Professor, Biological Sciences 2007- 2012 Clemson University, Assistant Professor, Biological Sciences 2004-2007 University of Utah, Research Associate, Neurobiology and Anatomy 2002-2004 University of Utah and King’s College London, UK (Joint position), Postdoctoral Fellow, MRC Centre for Developmental Neurobiology and Department of Neurobiology and Anatomy 1998-2002 King’s College London, London, UK, Post Graduate Student, MRC Centre for Developmental Neurobiology
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CLEMSON UNIVERSITY COLLEGE OF AGRICULTURE, FORESTRY AND LIFE SCIENCES
RESUME SUSAN CAROLINE CHAPMAN
DATE June 2016
PERSONAL DATA Associate Professor Department of Biological SciencesClemson University132 Long HallClemson, SC 29634 864 650 1684 Phone864 656 0435 Fax
EDUCATION2002 Ph.D. Developmental Neurobiology, King’s College London, University
of London, UK,1999 B.Sc. Science, Open University, Milton Keynes, UK1998 B.Sc. Neuroscience, University College London, University of London,
UK
PROFESSIONAL EXPERIENCE2012 - present Clemson University, Associate Professor, Biological Sciences2007- 2012 Clemson University, Assistant Professor, Biological Sciences2004-2007 University of Utah, Research Associate, Neurobiology and Anatomy2002-2004 University of Utah and King’s College London, UK (Joint position),
Postdoctoral Fellow, MRC Centre for Developmental Neurobiology and Department of Neurobiology and Anatomy
1998-2002 King’s College London, London, UK, Post Graduate Student, MRC Centre for Developmental Neurobiology
1997 King’s College London, London, UK, Wellcome Trust Summer Studentship, Randal Institute1996 UMDS (United Medical and Dental School), London, UK, Summer Studentship, Anatomy and Developmental Biology
MEMBERSHIPS1996-present Member, British Society for Developmental Biology, BSDB2000-present Member, Anatomical Society2001-present Member, Genetics Society, GS2002-present Member, Society for Developmental Biology, SDB2007-present Member, AAAS
2009-present Member, ASCB
PROFESSIONAL ACTIVITIES: National and International Service2015-present NSF Panelist
NIH Panelist (R21 Special Emphasis panel – Autism; R15 Special Emphasis panel – Environmental toxicants during development)
2015 Hearing Research UK, Ad Hoc grant reviewer2010-2016 Member: Editorial Board, Poultry Science2009-2013 NSF Graduate Recruitment Fellowship Panelist 2007-present Member: Editorial Board, Developmental Dynamics2005-present Reviewer: Ad Hoc, Wellcome Trust Grants Program (2005- present), Ad Hoc,
NSF (2008- present), Ad Hoc, MRC UK (2009- present), Czech Science Foundation (2011), Canadian Science Foundation (2011), BBSRC UK (2014- present)
2003-present Reviewer: Anatomical Record, Biotechniques, BMC Developmental Biology, Development, Developmental Dynamics, Frontiers in Biosciences, Journal of Anatomy, Journal of Neuroscience Research, Nature, Poultry Science, Transgenic Research, Developmental Biology, DNA and Cell Biology, Journal of Histotechnology, Toxicological Sciences
PUBLICATIONSRefereed Journal Publications* Graduate Student Co-authors** Undergraduate Student Co-authors1 High School Co-authors2016 Fgf3 and Fgf16 expression patterns define spatial and temporal domains in the
developing chick inner ear. Daniel Olaya-Sánchez, Luis Óscar Sánchez-Guardado, Sho Ohta, Susan C. Chapman, Gary C. Schoenwolf, Luis Puelles, and Matías Hidalgo-Sánchez. Brain, Structure and Function. 2016. DOI 10.1007/s00429-016-1205-12015
2015 Rho-associated kinase (ROCK)-mediated cytoskeletal reorganization drives mesenchymal condensation and regulates downstream molecular signaling. Poulomi Ray* and Susan C. Chapman. PLoS One. 2015 Aug 3;10(8):e0134702. doi: 10.1371/journal.pone.0134702. eCollection 2015.
2014 Nowlan H. Freese*, Brianna A. Lam*, Meg Staton, Allison Scott**, and Susan C. Chapman.. A novel gain-of-function mutation of the proneural IRX1 and IRX2 genes disrupts axis elongation in the Araucana rumpless chicken. PLoS ONE 9(11): e112364. doi:10.1371/journal.pone.0112364. Dana J Rashid, Susan C. Chapman, Hans CE Larsson, Chris Organ, Anne Bebin, Christa Merzdorf, Roger Bradley and Jack Horner. From dinosaurs to birds: a tail of evolution. EvoDevo. 2014, 5:25. doi:10.1186/2041-9139-5-25. Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics. Tugba G
Kucukkal, Ye Yang, Susan C. Chapman, Weiguo Cao and Emil Alexov. 2014 International Journal of Molecular Sciences. 15, 9670-9717.FRIZZLED10 mediates WNT1 and WNT3A signaling in the dorsal spinal cord of the developing chick embryo. Lisa M. Galli, Roeben N. Munji1, Susan C. Chapman, Ann Easton, Lydia Li, Ouma Onguka, Joseph S. Ramahi, Rowena Suriben, Linda A. Szabo, Camilla Teng, Baouyen Tran, Rami N. Hannoush and Laura W. Burrus. 2014 Developmental Dynamics. 243(6):833-43.
2012 Genome-wide Association Mapping and Identification of Candidate Genes for the Rumpless and Ear-tufted Traits of the Araucana Chicken. Rooksana E. Noorai*, Nowlan H. Freese*, Lindsay M. Wright**, Susan C. Chapman, Leigh Anne Clark. 2012 PLOS One, Vol7, Issue7:1-6.Cloning and expression analysis of Fgf5, 6 and 7 during early development. Megha Kumar* and Susan C. Chapman. 2012 Gene Expression Patterns, 12:245-253.
FGF signaling is required for specifying pre-chondrogenic identity in neural crest derived mesenchyme, but cannot initiate the chondrogenic program. Megha Kumar*, Poulomi Ray* and Susan C. Chapman. 2012 Developmental Dynamics, 241:1091–1103.
2011 Can you hear me now? Vertebrate Middle Ear Development. Susan C. Chapman. 2011 Frontiers in Biosciences. 16:1675-1692. (Review Article)
2010 Analysis of chick (Gallus gallus) middle ear columella formation. Jamie L Wood, Ami J Hughes**, Kathryn J Mercer1, Susan C. Chapman. 2010 BMC Developmental Biology, 10:16.Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms. Steven B. Bleyl, Yukio Saijoh, Noortje A.M. Bax, Adriana C. Gittenberger-de Groot, Lambertus J. Wisse, Susan C. Chapman, Jennifer Hunter, Hidetaka Shiratori, Hiroshi Hamada, Shigehito Yamada, Kohei Shiota, Scott E. Klewer, Mark F. Leppert and Gary C. Schoenwolf. Human Molecular Genetics, 2010: 1-16.
2009 Identification of differentially expressed genes in early inner ear development. Christian N. Paxton, Steven B. Bleyl, Susan C. Chapman, Gary C. Schoenwolf. 2009. Gene Expression Patterns, 10 (2010) 31-43. Chick embryo proliferation studies using EdU labeling. Michelle Warren**, Karolina Puskarczyk1, Susan C. Chapman 2009 Developmental Dynamics, 238:944-949.
2007 Specification of Germ Layer Identity in the Chick Gastrula. S.C. Chapman, K. Matsumoto, Q. Cai, G. C. Schoenwolf 2007. BMC Developmental Biology, 7:91.
2006 Restricted expression of Fgf16 within the developing chick inner ear. S.C. Chapman, Qin Cai, Steven B. Bleyl and G.C. Schoenwolf. 2006. Developmental Dynamics, 235:2276-2281.
2005 A Three-Dimensional Atlas of Pituitary Gland Development in the Zebrafish. S.C. Chapman, A.L. Sawitzke, D. Campbell and G.C. Schoenwolf. 2005 J. Comp. Neurol, Jul 11; 487(4):428-40.
Improvements in histology and signal retention following in situ hybridization in early chick embryos utilizing plastic resin and recolorization. Sawitzke, A.L., S.C. Chapman, S.B. Bleyl and G.C. Schoenwolf. 2005 Biotech. Histochem, 80(1): 35-41.Ubiquitous GFP expression in transgenic chickens utilizing a lentiviral vector. Chapman, S.C., A. Lawson, W.C. MacArthur, R.J. Wiese, R.H. Loechel, M. Burgos-Trinidad, J.K. Wakefield, R. Ramabhadran, T.J. Mauch and G.C. Schoenwolf. 2005 Development, 132:935-940.
2004 Rapid triple-labeling method combining in situ hybridization and double immunocytochemistry. Lopez-Sanchez C, Garcia-Martinez V, Lawson A, Chapman SC, Schoenwolf GC. 2004 Developmental Dynamics, Jun;230(2):309-15.Expression analysis of chick Wnt and Frizzled genes and selected inhibitors in early chick patterning. Chapman, S.C., Brown, R.P., Lees, L., Schoenwolf, G.C., Lumsden, A. Chick Special Issue. 2004 Developmental Dynamics, 229:668-676. The Neural Crest as a way of Knowing: New Perspectives on Lineage and Morphogenesis. Susan Chapman, David Raible, Deborah Henken, Kathryn Tosney. 2004 Developmental Dynamics, 229:140-142.
2003 Anterior identity is established in chick epiblast by hypoblast and anterior definitive endoderm. Chapman, S.C., Schubert, F.R.S., Schoenwolf, G.C., Lumsden, A. 2003 Development, 130 (21) 5091-5101.
2002 Analysis of spatial and temporal gene expression patterns in blastula and gastrula stage chick embryos. Chapman, S.C., Schubert, F.R.S., Schoenwolf, G.C., Lumsden, A. 2002 Developmental Biology, 245 (1) 187-199.
2001 Improved Method for Chick Whole-Embryo Culture Using a Filter Paper Carrier. Chapman, S.C., Collignon, J., Schoenwolf, G.C., Lumsden, A. 2001 Developmental Dynamics, 220:284-289.Lbx1 marks a subset of interneurons in chick hindbrain and spinal cord. Schubert, F.R., Dietrich, S., Mootoosamy, R.C., Chapman, S.C., Lumsden, A. 2001 Mechanisms of Development, 101(1-2):181-5.
Conference Proceedings (Reviewed and Unreviewed)* Graduate Student Presenting** Undergraduate Student Presenting1 High School Student Presenting2016 Lectin staining selectively highlights tissues within the embryonic chicken head.
Poulomi Ray, Ami L Hughes, Misha Sharif, Susan C Chapman. Southeast Society for Developmental Biology, Whitney Marine Laboratory, FL, 19-21 May 2016.
2015 Lectin staining selectively highlights tissues within the embryonic chicken head. Poulomi Ray, Ami L Hughes, Misha Sharif, Susan C Chapman. Anatomical Society, Cambridge, UK, Dec 2015.
2014 A novel gain-of-function mutation of the proneural Irx1 and Irx2 genes disrupts axis elongation in the Araucana rumpless chicken. Susan C Chapman. Southeast Society for Developmental Biology, Calloway Gardens, GA, 16-18 May 2014.
2013 Integration of mechanical and molecular signaling during skeletal condensation. Poulomi Ray* and Susan C. Chapman. Southeast Society for Developmental Biology, Nashville, TN, 13-15 May 2013.Fgf5 Signaling is required for lower jaw development during zebrafish embryogenesis. Chris McCoy* and Susan C. Chapman. Southeast Society for Developmental Biology, Nashville, TN, 13-15 May 2013.From gene to phenotype, what the Araucana rumpless chicken can tell us about tail development and Nowlan Freese* and Susan C. Chapman. LSB opening, Clemson, SC. February, 2013.Dynamic Cell Shape Changes are required for Mesenchymal Condensation. Poulomi Ray* and Susan C. Chapman. LSB opening, Clemson, SC. February, 2013.Araucana chicken as a model for DiGeorge syndrome. Rachel Bernstein** and Susan C. Chapman. LSB opening, Clemson, SC. February, 2013.
2012 Araucana chicken as a model for DiGeorge syndrome. Rachel Bernstein** and Susan C. Chapman. Clemson Biological Sciences 5th Annual Student Symposium, 1 December, 2012.From gene to phenotype, what the Araucana rumpless chicken can tell us about tail development (NF). Nowlan Freese* and Susan C. Chapman. Clemson Biological Sciences 5th Annual Student Symposium. 1 December 2012.Dynamic Cell Shape Changes are required for Mesenchymal Condensation. Poulomi Ray* and Susan C. Chapman. Clemson Biological Sciences 5th Annual Student Symposium. 1 December, 2012.Identification of a 2.1Mb region associated with the rumpless phenotype in the Araucana chicken breed. Nowlan Freese*, Rooksana Noorai, Leigh Anne Clark, Susan C. Chapman. Society for Developmental Biology, Montreal, Canada, 19-22 July 2012.Dynamic cell shape changes are required for mesenchymal condensation. Poulomi Ray* and Susan C. Chapman. Society for Developmental Biology, Montreal, Canada, 19-22 July 2012.Identification of a 2.1Mb region associated with the rumpless phenotype in the Araucana chicken breed. Nowlan Freese*, Rooksana Noorai, Leigh Anne Clark, Susan C. Chapman. Southeast Society for Developmental Biology, Memphis, TN, 25-27 May 2012.Dynamic cell shape changes are required for mesenchymal condensation. Poulomi Ray* and Susan C. Chapman. Southeast Society for Developmental Biology, Memphis, TN, 25-27 May 2012.
2011 Characterization of development in the rumpless Araucana chicken breed: a model for tail development defects. Nowlan Freese* and Susan C. Chapman. 6th International Chick Meeting. Roslin, Scotland, UK. 16-19 September 2011.
Premature down regulation of Tbx6 within the tailbud alters cell fates and leads to premature termination of axial elongation. Nowlan Freese*, Allison Scott, and Susan C. Chapman. Society for Developmental Biology. Chicago, IL. 21-25 July 2011.Pharyngeal endoderm and FGF signaling in induction and patterning of the chick middle ear columella condensation. Megha Kumar*, Poulomi Ray and Susan C. Chapman. Society for Developmental Biology. Chicago, IL. 21-25 July 2011.Mechanism of Mesenchymal Condensation during Chick Middle Ear Morphogenesis Poulomi Ray* and Susan C. Chapman. Society for Developmental Biology. Chicago, IL. 21-25 July 2011.Mechanism of mesenchymal condensation during middle ear morphogenesis. Poulomi Ray* and Susan C. Chapman. University of Florida, 2011 SE Regional Society for Developmental Biology Meeting. 17-19 May 2011.Premature down regulation of Tbx6 within the tailbud alters cell fates and leads to premature termination of axial elongation. Nowlan Freese*, Allison Scott, and Susan C. Chapman University of Florida, 2011 SE Regional Society for Developmental Biology Meeting. 17-19 May 2011.Pharyngeal endoderm and FGF signaling in induction and patterning of the chick middle ear columella condensation. Megha Kumar*, Poulomi Ray and Susan C. Chapman. University of Florida, 2011 SE Regional Society for Developmental Biology Meeting. 17-19 May 2011.Pharyngeal endoderm and FGF signaling in induction and patterning of the chick middle ear columella condensation. Megha Kumar*, Poulomi Ray and Susan C. Chapman. University of Florida, 2011 SE Regional Society for Developmental Biology Meeting (17-19 May 2011).The Mechanism of Mesenchymal Condensation during Middle Ear Morphogenesis. Poulomi Ray* and Susan C. Chapman. BSCB/BSDB Joint Spring Meeting. Canterbury, Kent, UK. 27-30 April 2011.
2010 Cellular mechanics of middle ear development. Poulomi Ray* and Susan C. Chapman. American Society for Cell Biology. Philadelphia, PA, 11-15 December 2010.Where’d my tail go? Nowlan Freese* and Susan C. Chapman. Society for Developmental Biology. Albuquerque, NM, 5-9 August 2010.Molecular Cloning And The Gene Expression Analysis Of Chick FGF5, 6 AND 7. Megha Kumar* and Susan C. Chapman, Southeast Society for Developmental Biology. UGA, 21-23 May, 2010.Where’d my tail go? Nowlan Freese* and Susan C. Chapman. Southeast Society for Developmental Biology. UGA, 21-23 May 2010.
2009 Middle ear columella formation in chick (Gallus gallus). Jamie L. Wood, Ami J. Hughes, Kathryn J. Mercer, Susan C. Chapman+. ASCB Annual Meeting, San Diego, CA, 5-9 December 2009.
2009 CBASS 2009, Nowlan Freese*, Susan C. Chapman. Talk – Characterization of tail development in the rumpless chicken Araucana. Clemson November 2009
2009 CBASS 2009, Poulomi Ray*, Susan C. Chapman. Tissue interactions during the development of the chicken middle ear. Clemson. 14 November 2009.CBASS 2009, Leiyin Zhu*, Susan C. Chapman. Talk – Creation of a GFP transgenic Zebrafish Line under the Control of the Sox9 E3 Enhancer. (November 2009).CBASS 2009, Megha Kumar*, Susan C. Chapman. Talk – The role of FGF signalling in the induction and patterning of the middle ear in chick embryo. (November 2009).Identification of differentially expressed genes in early inner ear development. Christian N. Paxton*, Susan C. Chapman, Gary C. Schoenwolf. Society for Developmental Biology, San Francisco, CA, 23-27 July 2009.Fate Mapping The Origin Of The Chick Middle Ear Columella. Poulomi Ray*, Ami Hughes, Sean Kitch, Jamie L. Wood, Susan C. Chapman. Hearing and Deafness, 7th Conference, Boston, MA, 20-23 June 2009.Proliferation studies in the chick ear-forming region using EdU labeling. Susan C. Chapman+. EB2009, New Orleans, LA, 18-22 April 2009.Identification of differentially expressed genes in early inner ear development. Christian N. Paxton+, Susan C. Chapman, Gary C. Schoenwolf. EB2009, New Orleans, LA, 18-22 April 2009.The Araucana Rumpless Phenotype Results From A Tail Organizer Developmental Defect. Nowlan Freese*, Purvi Amin and Susan C. Chapman, SESDB Regional Meeting, Birmingham, AL, 27-29 March, 2009.Analysis Of Fgf Gene Expression Patterns In The Ear-Forming Region Of The Chick. Megha Kumar* and Susan C. Chapman, SESDB Regional Meeting, Birmingham, AL, 27-29 March, 2009.
2008 SPRI presentation by Katy Mercer1 - Development of Chondrocytes and Osteoblasts in Relation to the Ossification of the Middle Ear Columella. Clemson, 18 July 2008.SPRI presentation by Karolina Pusharcyzk1 - Proliferation of Neural Crest-derived Cells for Columella Condensation. Clemson, 18 July 2008.Fgf gene expression patterns in the ear-forming region. Megha Kumar* and Susan C. Chapman. 67th SDB Annual Meeting, Philadelphia, 26-30 July 2008.
2007 Chick Middle Ear Development. Susan C. Chapman+. 6th Molecular Biology of Hearing and Deafness Conference, Wellcome Trust Conference Centre, Hinxton, UK. 11-14 July 2007.
PRESENTATIONS: Invited Symposia or Seminars2016 A novel gain-of-function mutation of the proneural Irx1 and Irx2 genes disrupts
axis elongation in the Araucana rumpless chicken. Kennesaw State University, September 2016.
2015 A novel gain-of-function mutation of the proneural Irx1 and Irx2 genes disrupts axis elongation in the Araucana rumpless chicken. USC Aiken, 27 Feb 2015.
2014 Using N-modified Creatine to treat SLC6A8-related Autism Spectrum Disorders. Greenwood Genetics Center. Self Regional Health Human Genetics Research Program launch. Greenwood, SC, 14 August 2014.A novel gain-of-function mutation of the proneural Irx1 and Irx2 genes disrupts axis elongation in the Araucana rumpless chicken. SESDB 2014, Callaway Gardens, Pine Mountain, GA 16-18 May 2014
2013 Integration of mechanical and molecular signaling during skeletal condensation. Session Chair: Morphogenesis and Organogenesis. Southeast Society for Developmental Biology, Nashville, TN, 13-15 May 2013.From gene to phenotype, what the Araucana rumpless chicken can tell us about tail development (NF). Jena job talk, Germany, 16 April 2013. Interplay of molecular and mechanical signaling during mesenchymal condensation (PR). Frank Costantini, Columbia University job talk, NY. 9-11 April 2013.From gene to phenotype, what the Araucana rumpless chicken can tell us about tail development (NF). Wilson Clements, St. Jude job talk, Memphis, TN. 21 March 2013.
2012 Interplay of molecular and mechanical signaling during mesenchymal condensation (PR). Jason Rock, UCSF job talk, San Francisco, CA. 5 December 2012. Changes in the bipotential fate of tail organizer cells leads to caudal axis truncation. Avian Model Systems 7th International Meeting. Nagoya, Japan. 10-15 November 2012.Dynamic cell shape changes are required for mesenchymal condensation (PR). Southeast Society for Developmental Biology, Memphis, TN, 25-27 May 2012.
2011 Characterization of development in the rumpless Araucana chicken breed: a model for tail development defects (NF). 6th International Chick Meeting. Roslin, Scotland, UK. 16-19 September 2011.Pharyngeal endoderm and FGF signaling in induction and patterning of the chick middle ear columella condensation (MK). University of Florida, 2011 SE Regional Society for Developmental Biology Meeting (17-19 May 2011).
2010 Where’d my tail go? New insights into axial extension for the Araucana chicken. University of Dundee, UK (21 October 2010).Araucana Tail Development. Session Chair: Morphogenesis and Organogenesis. University of Georgia Center for Continuing Education. 2010 SE Regional Society for Developmental Biology Meeting, UGA. 21-23 May 2010.
2009 Pharyngeal Endoderm is Required for Induction of the Columella Condensation in the Chick Middle Ear. IFAA Meeting, Cape Town, South Africa. August 2009.
2008 Middle Ear Development: identifying tissues and molecular interactions in induction and early patterning. G&B Seminar Series, Clemson University, Clemson, SC. November 2008.Middle Ear Development: identifying tissues and molecular interactions in induction and early patterning. Purdue University, Purdue, IN. November 2008.
2006 Inductive Tissue Interactions Pattern Regional Identity in the Chick Neuroectoderm. Clemson University, Clemson, SC. 16 February 2006.Inductive Tissue Interactions Pattern Regional Identity in the Chick Neuroectoderm. University of Miami, Miami. FL. 2 February 2006.
2005 Chick and Chips. Chicken Genome Workshop, Cold Spring Harbor Laboratory, CSH, NY. 8-11 May 2005.The chick as a model for head patterning. University of Colorado, Health Sciences Center, Denver, CO. 2 May 2005.
2003 Endoderm in Early Regional Patterning. University of Arizona, Tucson, AZ. 3 December 2003. Endoderm in Early Regional Patterning. Dine College, Tsaile, AZ. 1 December 2003.
HONORS AND AWARDS2016-2018 NIH R03 Structural analysis of Creatine and its role as a GABA A Receptor
neuromodulator2014-2016 Self Regional Health Foundation ‘Using N-Modified Creatine to Treat SLC6A8-
Related Autism Spectrum Disorders’2008-2014 NIH R01 Middle Ear Development 2008-2014 Experiment Station (Hatch) project: USDA/CSREES
SC-1700374: ‘Vertebrate middle ear development’.2012-2013 SC INBRE Pilot project2009-2011 NIH R01 Middle Ear Development ARRA Supplement2004-2008 NIH R01 Mechanisms of Pituitary Development (Research Associate) 2002-2004 Wellcome Trust Prize Fellowship 1998-2002 Wellcome Trust Prize Studentship 1995-1998 University College London – B.Sc. Neuroscience 1995-1998
UCL Prize for Neuroscience: 1st (1996), 2nd (1997) and 3rd year (1998),UCL Finalist Prize (1998), UCL Dean of Life Sciences Award for Academic Achievement (1998).
1997 Wellcome Trust Summer Studentship 1996 Howard Hughes Summer Studentship
PRIZES2015 Anatomical Society Best Images Award, ‘Full Frontal Face’, Susan Chapman and
Poulomi Ray2012 Nikon Small World, ‘Chick Embryo Intestinal Mucosa’, Top 100 images, Susan
Chapman and Poulomi Ray2012 Nikon Small World, ‘Chick Embryo Intestine’, Top 100 images, Susan Chapman and
Poulomi Ray2011 Science as Art, Clemson University, ‘This is Spinal Tap’, 2nd place, Susan Chapman,
Hilary Denney and Poulomi Ray2011 Science as Art, Clemson University, ‘El Pollo Diablo’, Susan Chapman and Allison Scott
SPONSORED RESEARCHActive Extramural Awards NIH R03 Structural analysis of Creatine and its role as a GABA A Receptor neuromodulator
(2016-2018). $150,000. PISelf Regional Health Foundation ‘Using N-Modified Creatine to Treat SLC6A8-Related Autism
Spectrum Disorders (2014-2016). $314,582. Co-PI
Completed Extramural AwardsMiddle Ear Development, R01 NIH NIDCD, Principle Investigator, $1,479,585, ($1,025,000), (2008-2014).SC INBRE Pilot project, $10,000 (2012-2013).Middle Ear Development Supplemental Award, American Recovery and Reinvestment Act 2009, R01 supplement NIH NIDCD, Principle Investigator, $223,500, ($148,500), (2009-2011).Mechanisms of Pituitary Development, Research Associate. R01 NIH NIDDK, $1,192,000, ($800,000), Research Associate Investigator (2004-2009).Patterning Anterior Identity in the Early Chick Embryo, Wellcome Trust Prize Fellowship, Post Doctoral Fellowship, Pounds Sterling 98,075 (Pounds Sterling 67,255), (2002-2004).
Creative Inquiry F2010-S2011 ($3,000)2010 EUREKA, (2010). Caleb Ahrns, Victoria Golaszewski, Amber Manley ($200 x 3
Supplies, $500 x 3 Professional Development).2009 SCLIFE, Michelle Warren (2009), $550.2008 Hatch USDA/CSREES 1700374 (2008-2011). Vertebrate Middle Ear Development
Public Service and Agriculture Next Generation Graduate Fellowships, Clemson University, 3 Graduate Studentships x $45,000 (2008-2010).SCLIFE, Purvi Amin (2008), $550.SPRI, Karolina Puskarczyk, Katy Mercer (2008), ($1,000).Ethics across the curriculum, 5/2008 ($200 - professional development).
PENDING GRANT SUPPORT (grants under review)2016 NIH R21 The chicken as a disease model for disc degeneration and ankylosing
spondylitis. $400,000 over two years. PD/PI. Montanta State University – Dana Rashid PI.
2016 NIH R15 Using N-modified Creatine to treat SLC6A8-related Autism Spectrum Disorders. $450,000 over three years. Resubmission due 16 October 2016
GRANTS WRITTEN – not funded2015 NIH R15 Using N-modified Creatine to treat SLC6A8-related Autism Spectrum
Disorders. $450,000 over three years.2015 NIH R21. Using N-modified Creatine to treat SLC6A8-related Autism Spectrum
Disorders. $405,000 over two years.2014 NIH R21. Non-synonymous missense SNPs in MECP2 and Autism Spectrum Disorder.
$412,500 over two years.2014 Autism causing mutations in CADM1 gene: molecular mechanism and treatment.
Submitted on May 1, 2014 to Self Research Institute in response to RFP dated 3/28/2014 for collaborations between Clemson University and Greenwood Genetics Center researchers. Proposal is for $597,990 of direct costs over three years.
2013 Physics-Based Approach to Understanding and Targeting Disease-Causing Missense Mutations; Sponsored by National Institutes of Health/DHHS October 2013.
2013 NSF pre-application. The evolution of the tail extension mechanism in amniotes. NSF IOS MCA, Principal Investigator. 18 January 2013.
2012 NIH R21 Usher Syndrome genes in interconnecting links of stereocilia, NIH NIDCD, Principle Investigator, $411,750. 5 October 2012.
2012 NIH R01 An Autosomal Dominant Genetic Defect in the Rumpless Araucana Chicken Breed Results in Caudal Truncation, NIH NIGMS, Principal Investigator, Leigh Ann Clark, Co-investigator, $1,484,130. 5 March 2012.
2011 NIH F31 Usher Syndrome genes in interconnecting links of stereocilia. NIH NIDCD, Principle Investigator, Brianna Lam Graduate Student Fellowship, $192, 951. 5 December 2011.
2011 NIH R01 An Autosomal Dominant Genetic Defect in the Rumpless Araucana Chicken Breed Results in Caudal Truncation. NIH NIGMS, Principal Investigator, Leigh Ann Clark, Co-investigator, $1,484,130. 5 February 2011.
2008 Genetic Mechanisms of Middle Ear Development. March of Dimes. Principal Investigator, $150,000. 19 June 2007.
OTHER SPONSORED ACTIVITY2013 Professional Enrichment Grant, SESDB 2013 ($750) (Nashville, Tennessee - PR)2012 Society for Developmental Biology Travel Award 7/2012 ($450) (Montreal,
Canada – NF)Society for Developmental Biology Travel Award 7/2012 ($450) (Montreal, Canada – PR)American Association of Anatomists (AAA) Travel Award, Experimental Biology Meeting, San Diego, CA April 21-25th 2012. $350 – MK.
2011 Professional Enrichment Grant, 6th Annual Chick Conference ($1000) (Edinburgh, Scotland - NF).BSGSA Travel Award, 4/2011 ($400) (BSCB/BSDB Joint Spring Meeting, April 2011-PR).Professional Enrichment Grant, Spring 2011 ($981), (BSCB/BSDB Joint Spring Meeting, April 2011-PR).Travel Award from BSGSA 8/2011 ($435) (SDB July 2011-MK).Professional Enrichment Grant, 8/2011 ($750) (SDB July 2011-PR).Professional Enrichment Grant, 5/2011, ($555) (SESDB May 2011-NF).Travel Award from BSDB 4/2011 (385 Pounds:~$635) (BSDB 2011-PR).
2010 Travel Award from SDB 8/2010 ($250) (SDB August 2010-NF).Professional Enrichment Grant, 7/2010, ($680) (SDB August 2010-NF).
Travel Award from BSGSA 8/2010 ($400) (SDB August 2010-NF). 2009 BSGSA Travel Award, 6/2009 ($400) (7th Molecular Biology of Hearing and
Deafness-PR).2008 Travel Award from SDB, 7/2008 ($200) (SDB July 2008-MK). 2007 Travel Award from Deafness Research UK, 7/2007 ($1000) (6th Hearing and
Deafness, July 2007-SCC).2001 Travel Award, Company of Biologists, Pounds Sterling 1,500, (2001-SCC).
Complete Graduate Advising (my lab)Graduated:Nowlan Freese, Ph.D. Biological Sciences, ‘A Novel Gain Of Function Of The Gene Iroquois1/2 Disrupts Axis 3 Elongation In The Araucana Rumpless Chicken’, (August 2013).
Poulomi Ray, Ph.D. Biological Sciences, ‘Early skeletal morphogenesis: the role of pharyngeal endoderm derived signaling during specification of craniofacial skeleton and interplay of mechanical forces and molecular signaling during skeletal condensation’, (May 2013).
Megha Kumar, Ph.D. Biological Sciences, ‘Specification of the neural crest derived pharyngeal mesenchyme: the role of pharyngeal endoderm, FGF and BMP signaling in the establishment of prechondrogenic identity and initiation of chondrogenesis’, (May 2012).
Changed major:Emily Trigg, M.S. student, ‘Zebrafish as a model for creatine deficiency syndrome’ (2015-16, Accepted industry position).Chris McCoy, M.S. student, ‘The role of Fgf5 in zebrafish craniofacial development’ (2012-13, moved to Environmental Toxicology, graduated Dec. 2014).Brianna Lam, Ph.D. student, ‘Zebrafish Usher Syndrome (2011-13, moved to UNC - Bioinformatics).Candler Paige, Ph.D. student, ‘The mechanism of rumplessness in the Araucana chicken’, (2012-13, move to MUSC – Behavioural studies).Leiyin Zhu, Ph.D. student, ‘Avian Middle Ear Development’, (2008-2010, changed to CU - Economics).
Current Graduate Student Committees (other labs)Dana Szymkowicz, Ph.D. Entox (2015-). Dr. Lisa Bain
Completed Graduate Student Committees (other labs)Arthur Brodsky, Ph.D. Bioengineering, ‘Mesenchymal stem cell expansion, Effects of ammonium on NS0 cells, Breast cancer stem cells and metastasis’ (2012-August 2015). Dr. Sarah Harcum, Bioengineering.Rooksana Noorai, Ph.D. Genetics, ‘Discovery Of Variants Underlying Simple And Complex Traits Through Genome-Wide Association Study And Whole-Genome Resequencing’ (2012-May 2014), Dr. Leigh Anne Clark, Genetics.Uma Mahajan, Ph.D. Microbiology student, "Interaction of mosquito larvae with Francisella
tularensis biofilm" (2008-May 2013). Dr. Tamara McNealy, Microbiology.Gia-Ming Hong, Ph.D. Environmental Toxicology student, ‘Developmental Effects of Arsenic’, (2008-Dec 2012). Dr. Lisa Bain, Entox.Sherri Hughes-Murphee, M.S. Genetics “Tree dormancy and chilling”, (2009-2011). Dr. Bert Abbott, Genetics.Farzana Ferdous, Ph.D. Biological Sciences student, ‘Chicken Immune System’, Dr. Tom Scott. (2010-2011, left committee. Candidate graduated 2014), Biological Sciences.Megan Ladd, M.S. Genetics, ‘The ontogeny of normal mRNA expression of genes from the SHFM3 critical region in developing chicken limb’. Dr. Charles Swartz. (2004-2009), Greenwood Genetics Center.
UNIVERSITY AND PUBLIC SERVICECommitteesUniversity: Faculty Scholar, CUSHR (2014-)Member, CUSHR TRP committee (2014-)Member, 2020 Health Research Taskforce (2015-16)Member, Faculty Senate (2010-13)Member, Faculty Senate Finance Committee (2010-13)Member, President’s Advisory Committee (2011-13)Member, Faculty Senate Budget Accountability Committee (2012-13)Member, Bookstore Advisory Committee (2012-13)Chair, Bookstore Advisory Committee, (2009-12)Member, Parking Advisory Committee (2012)Chair, Parking Advisory Committee (2010-11)Member, Accident Review Board (2010)Member, VP Research Search Committee (2009-10)
College:Chair, AVS Department Chair Search Committee (2012), hired Dr. James StricklandMember, Grant Support Services Advisory Committee (2008-12) Member, Life Sciences Building User Group Advisory Committee (2007-8)
Department: Chair, Genomics Search Committee, (2015-2016), hired Dr. Kara PowderMember, CLIF (2012-present)Member, Jordan Hall Imaging Facility Committee, (2007-2012)Member, Curriculum Committee, (2010-12).Member, Chair’s Advisory Committee (2010-2012).Member, UG Advisory Committee (2012-2015).
Other ServiceOrganizer: Grant Writing Workshop for Faculty (2009).
@ - student of underrepresented minorityBIOSC/MICRO/GEN4910 and H4910 Research Advisor: where are they nowAshley Parinella (Calhoun Honors) (S13-S14) on twitter, The Cares Clinic, Charleston, SC, Physician RecruiterMisha Sharif@ (Calhoun Honors) (S13-F13) Greenville Health System 2016Rachel Bernstein (F12-F13) Clemson University 2014, current position unknownHillary Denney (F10-S12) U. Kentucky College of Medicine 2019April Dove@ (S10) MUSC RN BSN Student 2017Allison Scott (F10) Villanova U. School of Law J.D. 2015 U. Miami, LL.M. Candidate 2016Purvi Amin, (S08, F08, S09) Medical College of Georgia, Physician Assistant, 2014Michelle Warren, (F08, S09) State Farm Sales AssociateMonique McKiever@, (F08, S09, F09) Vanderbilt, M.D. 2014, UTSouthwestern ObGyn 2019Ben Strickland (S09), current position unknown
BIOSC/MICRO/GEN4940 Creative Inquiry Research Advisor: Fall 16
Sarah Jackson (Calhoun Honors)Stephen Moore (Calhoun Honors) Kristyn Robinson (Calhoun Honors)Mary Kate Sullivan (Calhoun Honors)Katlyn Taylor (Calhoun Honors)Kyleigh Connolly
Undergraduate Research Lab Advisor (Paid or voluntary work): Kristyn Robinson (2016)Katlyn Taylor (2016)Mary Kate Sullivan (2016)Catherine Harvey (2014-15)Julie Gilbert (2013)Christina Mattingly (2013)Chris Gregorski (2012-2013)Jordan Elder (2012)Rachel Bernstein (2010-2014)Sara Smith (2011-13)Hilary Denney (2011)Allison Scott (2010-11)Ryan Vogelsberg (2011) Ami Hughes, (2008-2009)Tommy Sadowski, (2008-2009)
Research Assistant Lab Advisor (Paid work post B.S./B.A. degree)Charles Caleb Gruendling (2015)Chris Gregorski (2014)Hilary Denney (2012)Dylan Hale (2012)
Jesse Long (2010)Amy Anderson (2008-9)Sean Kitch (2008-9)
