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H2020 FET Open – Novel ideas for radically new technologies
Research and Innovation action
Proposal number: 858149
Without CA With Gd(III)-based CA
Extracellular Gd(III)-based agents in the clinical practice
N
N N
N
COO--
OOC
-OOC COO
-
Gd3+
NN
N
COO- COO
-
COO-
-OOC
-OOC
Gd3+
[GdDTPA]2- (Magnevist®)
[GdDOTA]- (Dotarem®)
N
N N
N
OH-OOC
-OOC COO
-
Gd3+ [GdHPDO3A] (ProHance®)
NN
N
COO- CONHCH3
COO-
-OOC
H3CHNOC
Gd3+
[GdDTPA-BMA] (Omniscan®)
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Hyperpolarized Molecules with biodistribution and pharmacokinetics analogous to the currently used Gd-Based Contrast Agents
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Click to edit Master title stylePartecipants
• Hadassah Medical Organization
Jerusalem, IL
• University of Torino
Torino, IT
• Danmarks Tekniske Universitet
Lingby, DK
• Universitaet Ulm
Ulm, DE
• University of Oxford
Oxford, UK
RS2D
Mundolsheim, FR
Max Planck Institute for Polymer Research
Mainz, DE
University of Cambridge,
Cambridge, UK,
EIBIR
Wien, AT
Fondazione Istituto Italiano di Tecnologia,
Genova, IT
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• Total contribution from EU
3.06 M Euros
• Time duration
3years
About the project
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Click to edit Master title styleAbout the project
PrimoGaia:A research project to generate a cheap MRI scanner able
to report on a specific enzymatic activity
The MRI detection occurs at low magnetic field strenght upon the polarization of water protons in contact with stable radicals (the responsive probe) whose epr resonance is irradiated at the earth
magnetic field.
further beyond conventional NMR
FFC NMR
INNOVATIVE SOLUTIONS FOR ANALYSIS
WHO WE ARE, WHAT WE
DO
Stelar holds proprietary know-how, technology and is unique in the NMR market
Stelar is an independent Italian company (SME) specialized in unique analytical instrumentation for Nuclear Magnetic Resonance
Stelar is committed to the diffusion of Fast Field Cycling NMR technology and products in new markets for scientific research and industrial applications
Stelar was established in Mede, Italy, in 1984 with the mission to develop, manufacture and market innovative and unique scientific analytical instrumentation