19
CNS Radiopharmaceuticals
Clinical Indications for Cerebral Scintigraphy
Blood Brain Barrier
Brain SPECT and PET Radiopharmaceuticals Used Clinically
Brain Perfusion ScanTc-99m HMPAO
FDA-Approved Radiopharmaceuticals
Radiopharmaceutical Approved Indications
Fluorine-18 fluorodeoxyglucose PET abnormal glucose metabolism in oncology and foci of epileptic seizures
Florbetapir florbetaben Flutemetamol Estimate β-amyloid neuritic plaque density
Indium-111 pentetate Cisternography
Iodine-123 ioflupane (DaTscan) Striatal dopamine transporter visualization
Iodine-123 human serum albumin Localization of cerebral neoplasms
Technetium 99m bicisate (Neurolite) Localization of stroke
Technetium 99m exametazine (Ceretec) Localization of stroke
Xenon-133 gas Cerebral flow
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Clinical Indications for Cerebral Scintigraphy
Blood Brain Barrier
Brain SPECT and PET Radiopharmaceuticals Used Clinically
Brain Perfusion ScanTc-99m HMPAO
FDA-Approved Radiopharmaceuticals
Radiopharmaceutical Approved Indications
Fluorine-18 fluorodeoxyglucose PET abnormal glucose metabolism in oncology and foci of epileptic seizures
Florbetapir florbetaben Flutemetamol Estimate β-amyloid neuritic plaque density
Indium-111 pentetate Cisternography
Iodine-123 ioflupane (DaTscan) Striatal dopamine transporter visualization
Iodine-123 human serum albumin Localization of cerebral neoplasms
Technetium 99m bicisate (Neurolite) Localization of stroke
Technetium 99m exametazine (Ceretec) Localization of stroke
Xenon-133 gas Cerebral flow
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Blood Brain Barrier
Brain SPECT and PET Radiopharmaceuticals Used Clinically
Brain Perfusion ScanTc-99m HMPAO
FDA-Approved Radiopharmaceuticals
Radiopharmaceutical Approved Indications
Fluorine-18 fluorodeoxyglucose PET abnormal glucose metabolism in oncology and foci of epileptic seizures
Florbetapir florbetaben Flutemetamol Estimate β-amyloid neuritic plaque density
Indium-111 pentetate Cisternography
Iodine-123 ioflupane (DaTscan) Striatal dopamine transporter visualization
Iodine-123 human serum albumin Localization of cerebral neoplasms
Technetium 99m bicisate (Neurolite) Localization of stroke
Technetium 99m exametazine (Ceretec) Localization of stroke
Xenon-133 gas Cerebral flow
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Brain SPECT and PET Radiopharmaceuticals Used Clinically
Brain Perfusion ScanTc-99m HMPAO
FDA-Approved Radiopharmaceuticals
Radiopharmaceutical Approved Indications
Fluorine-18 fluorodeoxyglucose PET abnormal glucose metabolism in oncology and foci of epileptic seizures
Florbetapir florbetaben Flutemetamol Estimate β-amyloid neuritic plaque density
Indium-111 pentetate Cisternography
Iodine-123 ioflupane (DaTscan) Striatal dopamine transporter visualization
Iodine-123 human serum albumin Localization of cerebral neoplasms
Technetium 99m bicisate (Neurolite) Localization of stroke
Technetium 99m exametazine (Ceretec) Localization of stroke
Xenon-133 gas Cerebral flow
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Brain Perfusion ScanTc-99m HMPAO
FDA-Approved Radiopharmaceuticals
Radiopharmaceutical Approved Indications
Fluorine-18 fluorodeoxyglucose PET abnormal glucose metabolism in oncology and foci of epileptic seizures
Florbetapir florbetaben Flutemetamol Estimate β-amyloid neuritic plaque density
Indium-111 pentetate Cisternography
Iodine-123 ioflupane (DaTscan) Striatal dopamine transporter visualization
Iodine-123 human serum albumin Localization of cerebral neoplasms
Technetium 99m bicisate (Neurolite) Localization of stroke
Technetium 99m exametazine (Ceretec) Localization of stroke
Xenon-133 gas Cerebral flow
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
FDA-Approved Radiopharmaceuticals
Radiopharmaceutical Approved Indications
Fluorine-18 fluorodeoxyglucose PET abnormal glucose metabolism in oncology and foci of epileptic seizures
Florbetapir florbetaben Flutemetamol Estimate β-amyloid neuritic plaque density
Indium-111 pentetate Cisternography
Iodine-123 ioflupane (DaTscan) Striatal dopamine transporter visualization
Iodine-123 human serum albumin Localization of cerebral neoplasms
Technetium 99m bicisate (Neurolite) Localization of stroke
Technetium 99m exametazine (Ceretec) Localization of stroke
Xenon-133 gas Cerebral flow
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
SPECT Agents
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Tracer Uptake Patterns
Tracer Uptake Pattern Cause
COLD (no uptake) CSFEdemaNecrosisSpace-occupying lesions (hemorrhage tumors cysts AVM postsurgery)
HYPOACTIVE (decreased uptake) IschemiaHypometabolism (hypofunction) degeneration deafferentationAtrophy
HYPERACTIVE (increased uptake) Luxury perfusionEncephalitisAcetazolamide-induced vasodilationHyperfunction (epilepsy [ictal] neuroactivation etc)Tumors
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Acetazolamide
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
18F-Fluorodeoxyglucose
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Iodine-123 ioflupane (DaTscan)
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
NORMAL ABNORMAL
DaTscan
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Cisternography
httpwwwcontroltfeumuseIanCSFCSF_diagramjpg
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
CSF leak study In-III DTPA- SPECT imaging of the head shows a small area of radiotracer extravasation in the left anterior skull base just lateral to the midline- SPECT and pledget counting indicate small CSF leak in the region slightly left to the midline in the left superior nasal cavity
Pledgetsserum counts ratioRt superior pledget 21Rt inferior pledget 16Lt superior pledget 40Lt inferior pledget 21
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Glance at PET Radiopharmaceuticals
Compound Application
O-15 H2O Blood flow
O-15 O2 Oxygen metabolismflow
O-15 or C-11 carboxyhemoglobin Blood volume
C-11 methionine Amino acid metabolism
C-11 methylpiperone Dopamine receptor activity
C-11 carfentanil Opiate receptor activity
C-11 flunitrazepam Benzodiazepine receptor activity
C-11 scopolamine Muscarinic cholinergic receptors
C-11 ephedrine Adrenergic terminals
F-18 fluorodeoxyglucose (FDG) Glucose metabolism
F-18 fluoro-L-dopa Presynaptic dopamine system
F-18 fluorothymidine (FLT) DNA synthesis
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
Suggested Articles
4 Booth TC The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes part 1 AJNR Am J Neuroradiol 2015 Feb36(2)229-35 doi 103174ajnrA3970 Epub 2014 Jun 5
![The [ F]Fluorodeoxyglucose Method for the Measurement …circres.ahajournals.org/content/circresaha/44/1/127.full.pdf · 127 The [18F]Fluorodeoxyglucose Method for the Measurement](https://static.documents.pub/doc/80x56/5af4e91e7f8b9a190c8da921/the-ffluorodeoxyglucose-method-for-the-measurement-the-18ffluorodeoxyglucose.jpg)
