ColinB.Josephson,M.D.,M.Sc.,F.R.C.P.C.,CSCN(EEG)
CurriculumVitae I.BIOGRAPHICALDATAName: ColinBruceJosephsonAddress: FoothillsMedicalCentre
Office3E45,TeachingResearchandWellnessBld.Calgary,AB,Canada,T2N2T9
Telephone: +1(403)220-4289Email: [email protected]: AssistantProfessorofNeurologyPrimaryDepartment: ClinicalNeurosciencesSecondaryDepartment: CommunityHealthSciencesFaculty: MedicineInstitution: UniversityofCalgaryII.ACADEMICRECORDOngoingdegree MastersofEpidemiologyDateexpected May2018Specialty EpidemiologyInstitution/City/Country UniversityofCalgary,Calgary,Canadai.Undergraduate Medicaldegree(MD)Datecompleted May2006Specialty MedicineInstitution/City/Country DalhousieUniversity,Halifax,Canada
BachelorofScience(Honours)Datecompleted April2000Specialty BiologyInstitution/City/Country Queen’sUniversity,Kingston,Canada
ii.SpecialProfessional NeurologyFRCP(C)Datecompleted June2013Specialty NeurologyInstitution/City/Country DalhousieUniversity,Halifax,Canadaiii.Graduateandpost-doctoral VisitingResearchScholarDatecompleted December2015Specialty BigDataresearchandanalyticsInstitution/City/Country FarrInstitute;UniversityCollegeLondon,London,UK
ClinicalResearchFellowDatecompleted June2013Specialty EpilepsyandEEGInstitution/City/Country UniversityofCalgary,Calgary,Canada
ClinicalResearchFellowDatecompleted February2011Specialty IntracranialVascularMalformationsInstitution/City/Country UniversityofEdinburgh,Edinburgh,UnitedKingdom
MastersofScience(Dean’sListHonours)Datecompleted September2003Specialty PhysiologyTitleofthesis Determination of sites in the Na(+)/H(+) Exchanger
Isoform1(NHE1)involvediniontranslocationSupervisor Dr.JohnOrlowskiInstitution/City/Country McGillUniversity,Montreal,Canadaiv.Licensure,certification,boards 2015-present CanadianSocietyforClinicalNeurophysiology(EEG)
certification2013-present CollegeofPhysiciansandSurgeonsofAlberta2013-present Fellow of the Royal College of Physicians and
SurgeonsofCanada2013-present Specialist Certificate, Neurology, Royal College of
PhysiciansandSurgeonsofCanada2009-2011 UnitedKingdomGeneralMedicalCouncil
2007-present LicentiateoftheMedicalCouncilofCanada(LMCC)2006-2013 NovaScotiaCollegeofPhysiciansandSurgeonsIII.AWARDSANDDISTINCTIONS2018 Named to theUniversityofCalgary’sHonourRollof
OutstandingUndergraduateMedicalTeaching2017 Acceptedintothe2017CanadianInstitutesofHealth
Research (CIHR) Early Career Investigators GrantReviewProgram
2017 Accepted intothe2017 InternationalLeagueAgainstEpilepsy(ILAE)LeadershipProgram
2016 12th European Congress on Epilepsy HighlyCommended Certificate for Poster Presentation of‘Adverse psychological effects of levetiracetamcompared to seven other common anti-epilepticdrugsinadultswithepilepsyingeneralpractice’
2015 AlbertaInnovationandAdvancedEducationGraduateStudentScholarshipfor$3000.00
2014 American Brain Foundation/American Academy ofNeurology/American Epilepsy Society/EpilepsyFoundation Susan S. Spencer Clinical ResearchTrainingFellowshipinEpilepsy
2014 Alberta Innovates Health Solutions (AIHS) ClinicianFellowshiprecipient
2013 CanadianInstitutesHealthResearch(CIHR)Fellowshiprecipient
2013 AmericanEpilepsySocietyFellowTravelAward2013 CanadianSocietyofClinicalNeurophysiologists(CSCN)
National Clinical Fellowship in Epilepsy andElectroencephalography
2013 Canadian League Against Epilepsy Mary Ann LeeAward for best neurology or neurosurgery residentresearch
2012 Dalhousie University Neurosciences Research Daybestoralpresentation
2011 Dalhousie University Faculty of Medicine ResearchDayDMAAAwardforbestoralpresentation
2011 Dalhousie University Department of MedicineResearchDayawardforbestoralpresentation
2010 European Stroke Conference Young Investigator oftheYearAward.
2010 Royal College of Physicians London ‘InternationalAdvisors as Partners: Models of Collaboration’Meetingawardforposterpresentation
2010 AngiomaAllianceTravelAward2006 Richard Payzant Ward Travel Bursary to attend the
CanadianCongressofNeurologicalSciences2006 DalhousieUniversityGrahamGwynMemorialPrizein
Neurology2006 DalhousieInternationalHealthOfficeTravelBursary2005 Recipient of Top Poster Presentation Prize at the
DalhousieFacultyofMedicineStudentResearchDay2004 Canadian Cardiovascular Academy “Have a Heart
Bursary”2003 AwardedDean’sListHonoursongraduationwithan
M.Sc.fromMcGillUniversity2002 Awarded runner-up for oral presentation at the 8th
Annual McGill University Department of PhysiologyGraduateStudentsResearchDay
2001 Awardedrunner-upforposterpresentationatthe7thAnnual McGill University Department of PhysiologyGraduateStudentsResearchDay
2000 Awarded the Faculty of Graduate Studies andResearch Fellowship as the top-ranked incominggraduate student toMcGill University’s DepartmentofPhysiology
2000 Ontario University Athletics (OUA) Academic All-OntarioStatus
1999 Ontario University Athletics (OUA) Academic All-OntarioStatus
1997-2001 MemberoftheQueen'sUniversityVarsityCurlingTeam
1997 AwardedDean'sListStatusatAcadiaUniversity1997 Recipient of the Clarke K. McLeod Pre-Medical
ScholarshipatAcadiaUniversity1996 Awarded a mid-year scholarship for academic
achievementatAcadiaUniversity
IV.ACADEMICAPPOINTMENTS2017-present MemberoftheDenaxasLaboratoryattheUniversity
of College London and Farr Institute of HealthInformaticsResearch
2016-present FullMember;HotchkissBrain Institute,University ofCalgary
2016-present Full Member; O’Brien Institute of Public Health,UniversityofCalgary
2016-present AssistantProfessorofNeurology;UniversityofCalgary2013-2015 Clinical Research Fellow in Epilepsy; University of
Calgary2011-2012 Co-ChiefResidentinNeurology;DalhousieUniversity2009-2011 ClinicalResearchFellowinVascularMalformationsof
theBrain;UniversityofEdinburghV.EDUCATIONALACTIVITIESi.Undergraduate 2017- UniversityofCalgaryFacultyofMedicineclassroom
lectureronepilepsyforCourseV:IntegratedNeurosciences,SpecialSensesandAging
2017- EvaluationchairoftheUniversityofCalgaryFacultyofMedicinecourseMDCN440:AppliedEvidenceBasedMedicine
2017- UniversityofCalgaryMDCN440:AppliedEvidenceBasedMedicinesmallgrouppreceptor
2015- UniversityofCalgaryClinicalCoreCourseV:IntegratedNeurosciences,SpecialSensesandAgingpreceptorforsmallgroupteachingofmedicalstudents
2014- UniversityofCalgaryClinicalCoreCourseV:IntegratedNeurosciences,SpecialSensesandAgingpreceptorforclinicalskillsteachingformedicalstudents
2008 TutorforDalhousieMedicalSchoolsmallgroupEpidemiologytutorials
2006-2013 InstructorforDalhousiesecondyearmedicalstudentclinicalskillsunit
2006-2012 ResponsibleforsupervisingmedicalstudentsrotatingthroughClinicalNeurology
2002 Teaching Assistant for Introductory PhysiologyLaboratoryCourseatMcGillUniversity
ii.Resident2016- PreparedandinvigilatedepilepsyOSCEsforresidents
fromthePGY-1to-5level2016- Mentored residents during their 3-month Epilepsy
Rotationincludinginclinic,readingEEGs,andontheSeizureMonitoringUnit
2016- University of Calgary Neurology Continuum Roundsfacilitator
2015- University of CalgaryNeurology Residents’ ‘Spot thebraincell’lectures
iii.Continuingmedicaleducation2017- Co-organiser for the Annual International Banff
EpilepsySymposium2017- Co-organiser for the 2017 1st Annual University of
Calgary’sCMEaccreditedCourseEpilepsyandSeizureManagement:BeyondtheER
iv.Supervision2018- Mr. Will Wilson; Master of Science candidate
(supervisorycommitteemember)2017-2018 Ms. Sanjana Sudershan; undergraduate Bachelor of
Health Sciences student project (co-supervised withDr.PamelaRoachforcourseMDSC507)
2017- Mr. KevinPerera; undergraduateBachelorofHealth
Sciences student project (co-supervised with Dr.NathalieJetteforcourseMDSC528)
2017 Ms.AyshaLukmanji;undergraduatesummerstudentfrom McGill University (co-supervised with Dr.NathalieJette)
2017 Mr.ConnorBranch;undergraduate summer student
from Carleton University (co-supervised with Dr.NathalieJette)
2016-2017 Ms. Ana Subota; undergraduate Bachelor of Health
Sciences student project (co-supervised with Dr.NathalieJetteforcourseMDSC507)
VI.ADMINISTRATIVERESPONSIBILITIESi.Departmental 2018 MemberoftheSearchandSelectionCommittee
foraNeurointensivistwithcross-appointmentsinNeurologyandCriticalCareattheUniversityofCalgary
2017- HeadoftheCalgaryComprehensiveEpilepsyProgramRegistry/ResearchProject
2017- FellowshipDirectorfortheUniversityofCalgary’sDivisionofEpilepsy
2017- Co-DirectorofEducationfortheUniversityofCalgary’sDivisionofEpilepsy
2017 MemberoftheSearchandSelectionCommitteeforanacademicadultepileptologistattheUniversityofCalgary
2016- Co-chairoftheDivisionofNeurologyResidentResearchSub-CommitteeoftheResidencyProgramCommittee
2011-2012 Co-chiefresidentfortheDivisionofNeurology2011-2012 MemberoftheDalhousieAdultNeurology
Resident-in-TrainingCommittee2008 MemberoftheinterviewcommitteeforDalhousie
AdultNeurologyResidencyProgram2003-2004 DalhousieUniversityMedIIClassRepresentative
fortheElectivesBlockoftheSchoolCurriculum2001-2002 PresidentoftheMcGillUniversityPhysiology
GraduateStudentAssociation
ii.Faculty 2017- EvaluationChairforUniversityofCalgaryFacultyof
MedicinecourseMDCN440:AppliedEvidence-BasedMedicine
2003-2004 Co-chairofthe2004AtlanticMedicalSchoolconferenceheldinHalifax,NS
2001-2002 Department of Physiology representative to theFacultyofGraduateStudies&Research
iii.University 2005-2006 MemberoftheinterviewcommitteeforDalhousie
MedicalSchooladmissions2001-2002 McGillUniversityPost-GraduateStudentSociety
(PGSS)Councilor1998 Memberoftheorganizingandleadershipteamof
theNewExchangeandTransferStudentOrientationWeek(NEWTS)atQueen'sUniversity
VII.PROFESSIONALACTIVITIESi.Membershipinprofessionalandlearnedsocieties
2015-present Canadian Society for Clinical Neurophysiology (EEG)certification
2013-present Fellow of the Royal College of Physicians andSurgeonsofCanada
2013-present CollegeofPhysiciansandSurgeonsofAlberta2013-present AlbertaMedicalAssociation2012-present AmericanEpilepsySociety2012-present CanadianLeagueAgainstEpilepsy2009-2011 GeneralMedicalCouncil2007-present LicentiateoftheMedicalCouncilofCanada(LMCC)2007-present AmericanAcademyofNeurology2007-present CanadianMedicalAssociation2007-present MedicalCouncilofCanada
ii.Professionalservice
Journalreview(adhoc)Completed1) Neurology2) CanadianMedicalAssociationJournal3) Stroke4) AdvancesinClinicalNeuroscienceandRehabilitation5) BritishMedicalJournal6) McMasterOnlineRatingofEvidence(MORE)7) CochraneDatabaseofSystematicReviews8) CanadianJournalofNeurologicalSciences9) JournalofNeurology,Neurosurgery,andPsychiatry10) ActaNeurologicaScandinavica11) EpilepsiaOpen12) Seizure13) BMJOpen14) JournaloftheNeurologicalSciences15) EpilepsyResearch16) Epilepsy&Behavior
Grantreview(adhoc)Completed2018 CIHRInstituteofNeurosciences,MentalHealthandAddiction2018 UnitedKingdomStrokeAssociation2017 UnitedKingdomStrokeAssociation2017 Office of the Associate Dean Research, University of Calgary, preliminary
reviewofCIHRSPORiCTRewardingSuccessInitiativeapplications.
Nationalandinternationalcommittees2018 InternationalPopulationDataLinkageNetwork(IPDLN) ConferenceReviewCommittee 2017- CanadianBoardofRegistrationofElectroencephalographTechnologists,
Inc.(C.B.R.E.T.,Inc.)Examiner2017- MemberoftheInternationalLeagueAgainstEpilepsyTaskForceonBig
Data/OpenData(ChairedbyDr.SamdenLhatoo) 2017- MemberoftheInternationalLeagueAgainstEpilepsySub-TaskForceon
Driving(ChairedbyDr.NathalieJette)2014-2016 CanadianLeagueAgainstEpilepsy(CLAE)JuniorMemberRepresentative
VIII.RESEARCHANDSALARYAWARDSUPPORTAmount Fundingagency Year(s)of
fundingProject/Activity
55,000.00(CAD) CFNCatalystGrantCompetition
2018-2019 TheEDGARstudy(ElderlywithepilepsyDruGAppRopriateness)
15,000.00(CAD) UniversityResearchGrantsCommitteeSeedGrant
2018 Creatingaprecisionmedicinepipelinefortheneurosciences
15,000.00(CAD) HotchkissBrainInstitute
2018 UseofCOX-2andCalciumChannelBlockersandepilepsyoutcomesinlarge,linkedelectronichealthrecords
102,000.00(CAD) UCBCanadaInc. 2018 Pan-CanadianObservationalStudyonEpilepsy(POSE)
3000.00(CAD) AlbertaInnovationandAdvancedEducationGraduateStudentScholarship
2015 MastersofEpidemiology
130,000.00(USD) AmericanBrainFoundation/AmericanEpilepsySociety/EpilepsyFoundation/AmericanAcademyofNeurology
2014-2016 SusanS.SpencerClinicalResearchTrainingFellowshipinEpilepsy
210,000.00(CAD) AlbertaInnovates:HealthSolutions
2014-2017 AlbertaInnovates:HealthSolutionsClinicianFellowship
165,000.00(CAD) CanadianInstitutesofHealthResearch
2013-2016 CanadianInstitutesofHealthResearchFellowship
65,000.00(CAD) CanadianSocietyofClinicalNeurophysiologists
2013 CanadianSocietyofClinicalNeurophysiologistsClinicalFellowshipinEpilepsyandElectroencephalography
IXINVITEDADDRESSESi.Invitedtalks2018 13thAnnualEuropeanCongressonEpileptology
• Session co-chair: Enabling precision medicine inepilepsythroughbighealthdataanalytics
• Presentation: Large, linked electronic andadministrative data and the epidemiology ofepilpesy
2018 53rd Annual Canadian Neurological Sciences
FederationCongress• A practical and clinically relevant review of the
newestgenerationAEDs2018 Invitedlecturesatl'UniversitédeMontréal,Montreal
• Grand rounds: Psychiatric comorbidities inepilepsy:thinkoutsidetheseizure
• Epilepsy rounds: Harnessing routine clinical datatoimproveefficiencyandadvanceresearch
2018 NationalEpilepsyReviewCourse(NERC)
• Presentation:Approachtoafirstseizure• Presentation:Medicalcomorbiditiesinepilepsy
2017 71stAnnualAmericanEpilepsySocietyMeeting
• Presentation: Epilepsy or just getting old?Diagnosticchallengesinelderly
2017 3rdAnnualAlbertaPROMsandEQ-5DResearchand
SupportUnit(APERSU)AnnualEnd-usermeeting• Presentation: EQ-5D scores in a large, hospital-
basedregistryofepilepsypatients2017 6thAnnualCampusAlbertaNeuroscienceSymposium
• Presentation:Bigdata andadvancedanalytics inepilepsy
2017 Hotchkiss Brain Institute-Melbourne Epilepsy
Symposium• Presentation: Linked Electronic Medical Records
as a Means of Studying the Epidemiology ofEpilepsy
2017 20th AnnualWestern EpilepsyWorkshop, Banff, AB,
Canada• Presentation: Some like it hot: a red (or scarlet)
herringoracauseofseizures?2016 7thAnnualCalgary Epilepsy Symposium,Calgary,AB,
Canada• Presentation: Some like it hot: a red (or scarlet)
herringoracauseofseizures?2016 7thAnnualCalgary Epilepsy Symposium,Calgary,AB,
Canada• Presentation:Thebest laidschemesofmiceand
mengooftawry:Theperilsofautoimmunity2016 Canadian League Against Epilepsy Biennial Meeting,
QuebecCity,QC,Canada• ModeratorfortheStatisticsinMedicinecourse• Presentation: An approach to meta-analytic
studies2016 Hotchkiss Brain Institute Research Day, Calgary, AB,
Canada• Big data in epilepsy: can Goliath finally conquer
David?2015 Canadian Epilepsy Research Initiative, Toronto, ON,
Canada• Bigdata:canGoliathfinallyconquerDavid?
2010 ScottishAuditof IntracranialVascularMalformations
10yearCelebration,Edinburgh,UK• Theriskofepilepticseizureafterthediagnosisof
acavernousorarteriovenousmalformations
2010 Annual Scottish Epilepsy Nurses Association (ESNA)
Meeting,Edinburgh,UK• Theriskofepilepticseizureandaclinicalauditof
patientcareafterthediagnosisofacavernousorarteriovenousmalformations
2007 DalhousieUniversityDepartmentofMedicineGrandRounds,Halifax,NS,Canada• FitsorFaints?
ii.Interviews 2018 NeurologyToday
• Causes, Mimics, and Pitfalls of Epilepsy in theElderly
2017 MedscapeNeurology
• Epileptic Activity Discovered in Late-OnsetAlzheimer's
2017 MedPageToday• The Effects of Mood and Anxiety Disorders in
Patients with Epilepsy: Could undetecteddepression or anxiety be the reason achievingseizurecontrolinpatientswithepilepsycanbesodifficult?
2017 ReutersHealth
• Associationofdepressionandtreateddepressionwith epilepsy and seizure outcomes: a multi-cohortanalysis.
2017 MedPageToday
• Associationofdepressionandtreateddepressionwith epilepsy and seizure outcomes: a multi-cohortanalysis.
X.PUBLICATIONS/PRESENTATIONSi.Peer-reviewedpublications1. WahbyS,KarnikV,SajobiTT,WiebeS,JosephsonCB.Cannabisuseisassociatedwith
worsehealthoutcomesinpeoplewithepilepsy:aprospectivecohortstudy.SubmittedtoNeurology.
2. JosephsonCB, Engbers J, Jette,N, Patten S, Sajobi, TT,MarshallD, LowerisonM, andWiebe S. Prescription trends and psychiatric symptoms following first prescription forseven common antiepileptic drugs in general practice Submitted to Epilepsy andBehavior.
3. SpringAM,PittmanDJ,Agha-KhaniY,JirschJ,PillayN,Bello-EspinosaLE,JosephsonCB,and Federico P. Interrater reliability and generalizability of high frequency oscillationevaluations.SubmittedtoFrontiersofNeurology.
4. Lukmanji S, SauroKM, JosephsonCB,AlturaKC,WiebeS, and JetteN.A Longitudinalcohort study on the impact of the clobazam shortage on patients with epilepsy.Epilepsia.2017Dec7.doi:10.1111/epi.13974.[Epubaheadofprint]
5. Josephson CB, Gonzalez-Izquierdo A, Denaxas S, Fitzpatrick N, Sajobi T, Engbers JDT,
Patten S, Jette N, and Wiebe S. Serotonin reuptake inhibitor use and mortality inepilepsy: findings from a contemporary linked electronic health records cohort study.Epilepsia.2017;58(11):2002-2009.
6. JosephsonCBandJette,N.Psychiatriccomorbiditiesinepilepsy.InternationalReviewof
Psychiatry.2017;29(5):409-424.
7. JosephsonCB,PattenSB,BullochA,WilliamsJVA,LavoratoD,FiestKM,andJetteN.Theimpactofseizuresonepilepsyoutcomes:anational,community-basedsurvey.Epilepsia.2017;58(5):764-771.
8. Josephson CB, Lowerison M, Vallerand I, Sajobi TT, Patten S, Jette N, and Wiebe S.
Associationofdepressionandtreateddepressionwithepilepsyandseizureoutcomes:amulti-cohortanalysis.JAMANeurology.2017;74(5):533-39.
9. FishmanJ,CohenG,JosephsonCB,CollierM,BharathamS,ZhangY,andWildI.Patientemotionsandperceptionsofantiepilepticdrugchangesandtitrationduringtreatmentforepilepsy.EpilepsyandBehavior.2017;69:44-52.
10. SpringA,PittmanDJ,Agha-KhaniA,JirschJ,PillayN,Bello-EspinosaLE,JosephsonCB,andFedericoP.Interraterreliabilityofvisuallyevaluatedhighfrequencyoscillations.ClinicalNeurophysiology.2017;128(3):433-41.
11. JosephsonCB,Sandy,S,Jette,N,Sajobi,TT,MarshallD,andWiebeS.Asystematicreview
ofclinicaldecisionrulesforepilepsy.EpilepsyandBehavior.2016;57(PtA):69-76• Editorialforthisarticle:PughMJ.Clinicaldecisionrulesforepilepsycare:Thecase
forthinkingbig.EpilepsyandBehavior2016;57(PtA):220-1
12. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,PillayN, andWiebe S. Towards a clinically informed, data driven definition of elderly-onsetepilepsy.Epilepsia.2016;57(2):298-305
13. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,PillayN, andWiebe S. An investigation into the psychosocial effects of the postictal state.Neurology.2016;86(8):723-30
14. Josephson CB*, Sauro K*, Clement F, Wiebe S, and Jette N. Medical versus invasive
therapyinAVM-relatedepilepsy:systematicreviewandmeta-analysis.Neurology.2015;86(1):64-71
• *=co-firstauthors15. JosephsonCB,RosenowF, andAl-Shahi SalmanR. Intracranial vascularmalformations
andepilepsy.SeminarsinNeurology.2015;35(3):223-234
16. SamarasekeraN,LerpiniereC,FonvilleAF,FarrallAJ,WardlawJM,WhitePM,TorgersenA,IronsideJW,SmithC,Al-ShahiSalmanR,LothianAuditoftheTreatmentofCerebralHaemorrhage (LATCH) collaborators (including Josephson, C). Consent for brain tissuedonationafter intracerebralhaemorrhage:acommunity-basedstudy.PLoSOne.2015;10(8):e0135043
17. Jinadasa T*, Josephson CB*, Boucher A, and Orlowski J. Determinants of Cation
Permeation and Drug Sensitivity in Predicted Transmembrane Helix 9 and AdjoiningExofacialRe-Entrant Loop5ofNa+/H+ExchangerNHE1. Journal. JournalofBiologicalChemistry.2015;290(29):18173-86
• *=co-firstauthors18. Josephson CB, White PM, Krishan A, Al-Shahi Salman R. Computed tomography
angiography ormagnetic resonance angiography for detection of intracranial vascular
malformations in patients with intracerebral haemorrhage. Stroke Cochrane Corner.2015;46:e2-e3
19. Josephson CB, White PM, Krishan A, Al-Shahi Salman R. Computed tomographyangiography ormagnetic resonance angiography for detection of intracranial vascularmalformations in patients with intracerebral haemorrhage. Cochrane Database ofSystematic Reviews 2014, Issue 9. Art. No.: CD009372. DOI:10.1002/14651858.CD009372.pub2.
20. MoultrieF,HorneMA,JosephsonCB,HallJM,CounsellCE,WarlowCP,PapanastassiouV,Murray GD, Al-Shahi Salman R and the Scottish Audit of Intracranial VascularMalformations collaborators. Outcome after surgical or conservative management ofcerebral cavernous malformations: prospective, population-based cohort study.Neurology.2014;83(7):582-589
• Editorialforthisarticle:BernardiniGLandStapfC.Cavernomatoday:Keepthesurgeonaway?Neurology.2014;83(7):576-577.
21. Al-Shahi SalmanR,WhitePM,CounsellCE,duPlessis J, vanBeijnum J, JosephsonCB,WilkinsonT,WedderburnCJ,SallonZ,BhattacharyaJJ,PapanastassiouV,St.GeorgeEJ,RitchieV,RobertsRC,SellarRJ,WarlowCPandtheScottishAuditofIntracranialVascularMalformationscollaborators.Outcomeafterconservativemanagementortreatmentofunruptured brain arteriovenous malformations or associated arterial aneurysms:prospective,population-basedcohortstudy.JAMA.2014;311(16):1661-1669
22. JosephsonCB,DykemanJ,FiestKM,LiuX,SadlerRM,JetteN,andWiebeS.Systematicreview and meta-analysis of standard vs selective temporal lobe epilepsy surgery.Neurology.2013;80(18):1669-1676.
• Editorialforthisarticle:MathernGWandMillerJW.Outcomesfortemporallobeepilepsyoperationsmaynotbeequal:AcallforanRCTofATLvsSAHNeurology.2013;80(18):1630-1631.
• PatientPageforthisarticle:KarceskiS.Temporallobeepilepsysurgery:Whatisthebestapproach?/AboutEpilepsy.Neurology.2013;80(18):e192-e194.
23. Josephson CB, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V, Roberts RC,Sellar R, Warlow CP, and Al-Shahi Salman R. Seizure risk with AVM treatment orconservativemanagement:prospective,populationbasedstudy.Neurology.2012;79(6):500-507.
• Editorial for this article: Stapf C. Interventional AVM therapy against epilepticseizures:TreatmentbetweenScyllaandCharybdis?Neurology.2012;79(6):492-493.
24. JosephsonCBandPohlmann-EdenB.The“natural”historyofmedicallytreatedtemporal
lobe epilepsy: what can an evidence-based approach tell us? Epilepsy Research andTreatment.2012;vol212,ArticleID216510
25. Al-Shahi Salman R, Hall JM, Horne MA, Moultrie F, Josephson CB, Bhattacharya JJ,CounsellCE,MurrayGD,PapanastassiouV,RitchieV,RobertsRC,SellarRJ,WarlowCP.The untreated clinical course of cerebral cavernous malformations: prospective,population-basedcohortstudy.LancetNeurology.2012;11(3):217-224
26. Josephson CB, Leach JP, Duncan R, Roberts RC, Counsell CE, and Al-Shahi Salman R.Seizure risk from cavernous or arteriovenous malformations: prospective population-basedstudy.Neurology.2011;76(18):1548-1554.
• Editorialforthisarticle:HauserWAandMohrJP.Seizures,epilepsy,andvascularmalformations.Neurology.2011;76:1540-1541
27. JosephsonCB,FrantziasJ,SamarasekeraN,andAl-ShahiSalmanR.Thepersistingburdenofintracerebralhaemorrhage:caneffectivetreatmentsbefound?PLoSMedicine.2010;7(10):e1000353
28. JosephsonCBandAl-ShahiSalmanR.CananiPhoneapphelpstrokephysicians?LancetNeurology.2010;9(8):765
29. JosephsonCB,Al-AzriS,SmythDJ,HaaseD,and JohnstonBL.AcaseofPott’sdiseasewith epidural abscess andprobable cerebral tuberculoma followingBacillus Calmette-Guerin therapy for superficial bladder cancer. Can J Infect DisMedMicrobiol. 2010;21(1):e75-78
30. Josephson CB, Grant I, and Benstead T. Opsoclonus-myoclonus with multipleparaneoplasticsyndromesandVGCCantibodies.CanJNeurolSci.2009;36(4):512-514
31. JosephsonCB,PhillipsSJ,andAl-ShahiSalmanR.BMJEndgames:Anepisodeoftransientneurologicalsymptoms.AreviewofthediagnosisandmanagementofTIAs.BMJ.2009;338:b616.
32. JosephsonCB,DelgadoD,SchiffJ,andRossH.Theeffectivenessofrenaltransplantationasatreatmentforrecurrenturemiccardiomyopathy.CanJCardiol.2008;24(4):315-317
33. Josephson CB, Rahey S, and Sadler RM. Neurocardiogenic syncope: frequency andconsequencesofitsmisdiagnosisofepilepsy.CanJNeurolSci.2007;34:221-224
34. JosephsonCB,HowlettJG,JacksonSD,FinleyJ,andKellsCM.Acaseseriesofsystemic
right ventricular dysfunction post atrial switch for simple D-transposition of the greatarteries:theimpactofbeta-blockade.CanJCardiol.2006;22(9):769-772.
ii.Books,chapter1. JosephsonCBandWiebeS.Chapter3:Medication-resistantepilepsy:Ananalysisofthe
definitionanditsuse.2016in:STERN&SPERLING:Medication-ResistantEpilepsy
2. JosephsonCBandAl-ShahiSalmanR.Chapter9:Haemorrhage:newandrecurrent.In:Rigamonti, D, editor. 2011 in: Cavernous Malformations of the Nervous System.Cambridge:CambridgeUniversityPress
iii.Presentations/abstracts1. WahbyS,KarnikV,Wiebe,S,andJosephsonCB.Cannabisuseandpatientreported
outcomemeasuresinaprospective,tertiary-carecohortofpatientswithepilepsy.Submittedtothe2018EuropeanCongressonEpileptology.
2. KhanS,SubotaA,SudershanS,JetteN,BranchC,LukmanjiA,WiebeS,andJosephsonCB.Biomarkersinthepostictalstate:asystematicreviewandmeta-analysis.Submittedtothe2018EuropeanCongressonEpileptology.
3. WahbyS,KarnikV,SajobiTT,WiebeS,JosephsonCB.Cannabisuseandpatientreportedoutcomemeasuresinaprospective,tertiary-carecohortofpeoplewithepilepsy.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).
4. SudershanS,KhanS,SubotaA,LukmanjiA,BranchC,RoachP,JetteN,WiebeS,BuchhalterJ;FedericoP,TeskeyGC,andJosephsonCB.Biomarkersinthepostictalstate:asystematicreviewandmeta-analysis.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).
5. KhanS,SubotaA,LukmanjiS,JetteN,RoachP,WiebeS,BuchhalterJ,FedericoP,TeskeyGC,JosephsonCB.ASystematicReviewandMeta-AnalysisofSignsandSymptomsofthePost-IctalStateinEpilepsy.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).
6. GelfandJ,LeeJ,KhanS,CrooksR,JosephsonCB,WiebeS,PattenS,KorngutL,SmithE,andRoachP.Patientperspectivesregardingknowledgegapsandresourcesforepilepsy:
Aqualitativestudy.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).
7. SajobiTT,MenonBK,JosephsonCB,HillMD,QuanH,andWiebeS.Acomparisonofcost
sensitivemachinelearningclassifiersforpredictingrareoutcomes.WesternCanadaUniversitiesBigDataHealthConference,Banff,AB;September2017(posterpresentation).
8. LukmanjiS,SauroK,JosephsonCB,WiebeS,NurseS,andJetteN.ALongitudinalCohortStudyontheImpactoftheClobazamShortageonPatientswithEpilepsy:APatientPerspective.CanadianLeagueAgainstEpilepsyBiennialMeeting,Vancouver,BC;October2017(posterpresentation)
9. LethbeGC,JosephsonCB,WiebeS,LowerisonMW,LethbeBC,andWilliamsonT.EffectofadmittancetotheSeizureMonitoringUnitonaggregatehealthcareresourceutilization.CampusAlbertaStudentsConferenceonHealth(CASCH;Banff,Canada)September2017(posterpresentation)
10. JosephsonCB,Gonzalez-IzquierdoA,DenaxasS,FitzpatrickN,SajobiT,EngbersJ,PattenS,JetteN,andWiebeS.Serotoninreuptakeinhibitoruseandmortalityinepilepsy:findingsfromacontemporarylinkedelectronichealthrecordscohortstudy.InternationalEpilepsyCongress(Barcelona,Spain)September2017(posterpresentation)
11. JosephsonCB,Gonzalez-IzquierdoA,DenaxasS,FitzpatrickN,SajobiT,EngbersJ,PattenS,JetteN,andWiebeS.Serotoninreuptakeinhibitoruseandmortalityinepilepsy:findingsfromacontemporarylinkedelectronichealthrecordscohortstudy.InformaticsforHealth2017,AFarrInstitutescientificconference(Manchester,UK)April2017(platformpresentation)
12. LukmanjiS,SauroK,JosephsonCB,WiebeS,NurseS,andJetteN.ALongitudinalCohort
StudyontheImpactoftheClobazamShortageonPatientswithEpilepsy:APatientPerspective.AnnualCalgaryEpilepsyProgramandtheHotchkissBrainInstituteEpilepsyNeuroteamResearchRetreat(Calgary,Canada)March2017(platformpresentation)
13. JosephsonCB,LowerisonM,VallenrandI,SajobiTT,PattenS,JetteN,WiebeS.Amulti-cohortapproachtoestablishingmajordepressivedisorderasbothanindependentriskfactorandmodifieroftheexpressionofepilepsy.EuropeanEpilepsyCongress(Prague,CzechRepublic)September2016(platformpresentation)
14. Josephson CB, Engbers JDT, Patten S, Lowerison M, Sajobi TT, Jette N, Wiebe S.Psychologicaladverseeffectsof levetiracetamcomparedtosevenothercommonanti-
epilepticdrugsinadultswithepilepsyingeneralpractice;anupdatedanalysis.EuropeanEpilepsyCongress(Prague,CzechRepublic)September2016(posterpresentation)
15. Fishman J, Cohen G, Josephson CB, CollierM, Bharatham S, Zhang Y,Wild I. Patientemotionsandperceptionsofantiepilepticdrugchangesandtitrationduringtreatmentforepilepsy.AmericanAcademyofNeurology (Vancouver,Canada)April 2016 (posterpresentation)
16. Ewert K, Engbers J, Sajobi T, Josephson CB, Jetté N,Wiebe S. Predictingmortality in
epilepsy in general practice. American Epilepsy Society Meeting (Philadelphia, USA)December2015(posterpresentation)
17. LowerisonMW,EngbersJ,SajobiT,JosephsonCB,JettéN,WiebeS.ImpactofexposuretoneurologicalspecialistcareonmortalityinepilepsyinaCanadianprovincepopulation.American Epilepsy Society Meeting (Philadelphia, USA) December 2015 (posterpresentation)
18. Engbers,J,JosephsonCB,LunneyM,LowerisonM,PattenS,JettéN,WiebeS.Adverse
psychological effects of Levetiracetam in adults with epilepsy in general practice.American Epilepsy Society Meeting (Philadelphia, USA) December 2015 (posterpresentation)
19. LunneyM, Sauro, K, AtkinsonM, Josephson CB, Girgis F, Singh S, Patten SB, JettéN,
Hader W,Wiebe S. Identification of themes relevant to patients’ evaluation of theirsatisfactionwith epilepsy surgery through focus group discussions. American EpilepsySocietyMeeting(Philadelphia,USA)December2015(posterpresentation)
20. Josephson CB, Sauro, K., Clement, F.,Wiebe, S. and Jette N.Medical versus invasive
therapy in AVM-related epilepsy: systematic review and meta-analysis. InternationalEpilepsyCongress(Istanbul,Turkey)September2015(posterpresentation)
21. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,Pillay
N, andWiebe S. Epilepsy in the elderly: a distinct entity? American Epilepsy SocietyAnnualMeeting(Seattle,USA)December2014(posterpresentation)
22. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,PillayN, andWiebe S. The clinical and psychosocial impact of the postictal state. AmericanEpilepsySocietyAnnualMeeting(Seattle,USA)December2014(posterpresentation)
23. Josephson CB, and Pillay N. A case of intractable focal epilepsy. Western EpilepsyConference(Banff,Canada)February2014(platformpresentation)
24. Josephson CB, and Jette N. A case of status epilepticus in the context of AngelmanSyndrome.Mary Ann Lee Annual Meeting (Calgary, Canada) October 2013 (platformpresentation)
25. JosephsonCB,andWiebe.Aselectiveapproachtoastandardproblem?Comparisonofselective amygdalohippocampectomy and standard anterior temporal lobe resection.InternationalLeagueAgainstEpilepsyMeeting(Montreal,Canada)June2013(platformpresentation)
26. JosephsonCB,DykemanJ,FiestKM,LiuX,SadlerRM,JetteN,andWiebeS.Comparisonofstandardandselective temporal lobesurgery:systematic reviewandmeta-analysis.American Epilepsy Society AnnualMeeting (San Diego, USA), December 2012 (posterpresentation)
27. Josephson CB, and Al-Shahi Salman R. The 30-day complication rate following brainarteriovenous malformation/aneurysm embolisation: prospective population-basedstudy. 1st Annual World AVM Congress (Edinburgh, UK) September 2012 (platformpresentation)
28. Josephson CB, Al-Shahi Salman R, Hall JM, Horne MA, Moultrie F, Bhattacharya JJ,CounsellCE,MurrayGD,PapanastassiouV,RitchieV,RobertsRC,SellarRJ,WarlowCP.Untreated clinical course of cerebral cavernous malformations: a prospective,population-based cohort study.AtlanticNeurosciencesMeeting (Halifax, Canada)May2012(platformpresentation)
29. Josephson CB, Gubitz GG, and Philips SJ. A case of neurovascular syphilis. CanadianStrokeCourse(Toronto,Canada)February2012(platformpresentation)
30. Josephson CB, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V, Roberts RC,SellarR,WarlowCP,andAl-ShahiSalmanR. Seizureoutcomesafter interventionalorconservative management of brain arteriovenous malformations: prospective,populationbasedcohort study.AmericanEpilepsySocietyAnnualMeeting (Baltimore,USA)December2011(posterpresentation)
31. JosephsonCB,LeachJP,DuncanR,RobertsRC,CounsellCE,andAl-ShahiSalmanR.Theriskofepilepticseizureafterthediagnosisofacavernousorarteriovenousmalformation.
Dalhousie University Faculty of Medicine Research Day (Halifax, Canada) May 2011(platformpresentation)
32. JosephsonCB,LeachJP,DuncanR,RobertsRC,CounsellCE,andAl-ShahiSalmanR.Theriskofepilepticseizureafterthediagnosisofacavernousorarteriovenousmalformation.Dalhousie University Department of Medicine Research Day (Halifax, Canada) March2011(platformpresentation)
33. JosephsonCB,LeachJP,DuncanR,RobertsRC,CounsellCE,andAl-ShahiSalmanR.Therisk of epileptic seizure after the diagnosis of a cavernousmalformation of the brain:prospective,population-basedstudy.AngiomaAlliance6thAnnualPathobiologyofCCMScientificWorkshop(Washington,USA)November2010(platformpresentation)
34. Josephson CB, Frantzias J, and Al-Shahi Salman R. An audit of the management ofepilepsyaffectingadultswithacavernousorarteriovenousmalformationofthebrain.AnnualScottishNeurosciencesCouncilandtheNeurologicalAllianceofScotlandMeeting(Edinburgh,UK)September2010(posterpresentation)
35. Josephson CB, Leach JP, Duncan R, Roberts RC, Counsell CE, and Al-Shahi Salman R.Seizure risk from cavernous or arteriovenous malformations: prospective population-basedstudy.RoyalCollegeofPhysiciansandSurgeons (London) InternationalAdvisorsMeeting(London,UK)June2010(posterpresentation)
36. Josephson CB, Leach JP, Duncan R, Roberts RC, Counsell CE, and Al-Shahi Salman R.Seizure risk from cavernous or arteriovenous malformations: prospective population-based study. European Stroke Conference (Barcelona, Spain) May 2010 (platformpresentation)
37. Josephson CB, Al-Azri S, Smyth DJ, Haase D, and Johnston BL. Mycobacterium bovisvertebral osteomyelitis, epidural abscess, andpossible cerebral tuberculoma followingintravesical BCG therapy. CanadianNeurological Sciences FederationMeeting (Halifax,Canada)June2009(posterpresentation)
38. Josephson CB, Grant I, and Benstead T. Opsoclonus-myoclonus with multipleparaneoplastic syndromes and VGCC antibodies. Canadian Neurological SciencesFederationMeeting(Halifax,Canada)June2009(posterpresentation)
39. JosephsonCB,andWeaverD.Consciousnessandtheroleofgamma-wavesynchronicityinsensorybinding.JulianJaynesConferenceonConsciousness(Charlottetown,Canada)August2008(platformpresentation)
40. Josephson CB, Rahey S, and Sadler RM. Neurocardiogenic syncope: frequency and
consequencesofitsmisdiagnosisofepilepsy.CanadianCongressofNeurologicalSciences(Montreal,Canada)June2006(platformpresentation)
41. JosephsonCB,GubitzGG,andPhillipsSJ.Pre-strokefunctionalstatusinfluencesoutcome
inpatientsclassifiedaccordingtotheOCSPsubtype.CanadianCongressofNeurologicalSciences(Montreal,Canada)June2006(platformpresentation)
42. JosephsonCB,HowlettJG,JacksonSD,FinleyJ,andKellsCM.SystemicRightVentricular
Dysfunction Post Atrial Switch for Isolated D-Transposition of the Great Arteries: TheImpactofBeta-Blockade.CanadianCardiovascularCongress (Calgary,Canada)October2004(posterpresentation)
43. Josephson CB, and Orlowski J. Determination of Sites in the Na(+)/H(+) Exchanger
Isoform 1 (NHE1) Involved in Ion Translocation. NHE Congress on Advances in Na-HExchange Research: From Molecular Regulation to Therapeutic Advances (A satellitesymposiumofIUPHAR2002)(London,Canada)July2002(posterpresentation)