Commentary on Candidate Evidence Human Biology: Question Paper … · Human Biology: Question Paper...

Commentary on Candidate Evidence

Human Biology: Question Paper

1

Commentary on candidate evidence Candidate 1

The evidence for this candidate has achieved the following marks for each question of this Course Assessment component.

Question 1

The candidate was awarded 2 marks.

(a) 1 mark

(b) 0 marks – No mention is given of embryonic stem cells.

(c) (i) 1 mark

(ii) 0 marks

Question 2


(a) 1 mark

(b) (i) 0 marks – Answer is wrong. A frameshift mutation involves a base or

nucleotide being inserted or deleted. It is a splice-site mutation that involves the

retention of introns.

(ii) 0 marks

(c) 0 marks

(d) 1 mark

Question 3


(a) 1 mark – Quantity is too vague a term in comparison to volume, mass or

concentration.

(b) (i) 2 marks – One zero at the origin means candidate is not penalised for no

zero on the vertical axis scale.

(ii) 0 marks

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(iii) 1 mark – Use more dishes implies repeating the investigation.

(c) (i) 0 marks

(ii) 0 marks

(iii) 1 mark

Question 4


(a) 1 mark

(b) 0 marks

(c) 1 mark

(d) 0 marks – The lack of ATP for the next stage is not what results in the

reaction going backwards. It is the increase in fructose-6-phosphate

concentration which causes this.

(e) 0 marks

Question 5


(a) (i) 1 mark

(ii) 1 mark – ‘It’ must refer to creatine phosphate as this is what the question is

about and creatine phosphate is given in the stem of the question.

(b) 1 mark

(c) 2 marks – ‘Quick bursts of activity’ does not gain a mark as candidates need

to indicate ‘contraction’ over a short period.

Question 6

The candidate was awarded 1 mark.

(a)(i) 0 marks

(ii) 1 mark

(iii) 0 marks

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(b) 0 marks

Question 7


(a) 1 mark

(b) 1 mark

(c) 1 mark

(d) 2 marks – ‘Fit and work out’ indicates that the celebrities promote exercise.

Question 8


(a) 1 mark

(b) 1 mark

(c) 0 marks – Although the candidate has correctly worked out the answer, they

have entered the wrong figure in the answer line.

(d) (i) 1 mark

(ii) 1 mark

(iii) 1 mark

Question 9


(a) 0 marks

(b) 0 marks

(c) 0 marks

Question 10


(a) 1 mark – ‘two separate groups’ does not indicate related information

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being grouped together.

.

(b) 0 marks

(c) 0 marks

Question 11


(a)(i) 2 marks – Candidate gives a description of vasodilation.

(ii) 0 marks

(b) 0 marks

Question 12


(a) 1 mark

(b) 1 mark

(c) 0 marks

(d) 0 marks

Question 13


(a)(i) 0 marks

(ii) 1 mark

(iii) 1 mark

(b) 0 marks

(c) 0 marks

5

Question 14


(B)(i) 3 marks for mentioning points 1, 3, and 4.

Note the mark for point 2 is not given as impulses at the AVN do not cause

the atria to contract. It is impulses from the SAN which do this.

(ii) 5 marks for mentioning points a, b, c, d, e and f.

Total mark

The evidence for this candidate has achieved an overall mark of 42 for the paper.

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Candidate 2


Question 1


(a) 1 mark

(b) 1 mark

(c) (i) 1 mark – Answer indicates that stem cells are grown (in a lab?) after being

taken from the patient’s muscle.

(ii) 0 marks

Question 2


(a) 0 marks

(b) (i) 0 marks

(ii) 0 marks – Note candidate cannot be given credit for giving the correct

answer for part (i) here.

(c) 0 marks

(d) 0 marks

Question 3


(a) 0 marks – Incubator set to same time is unclear. Answer should have said set

to same temperature or dishes left in incubator for the same time.

The yeast answer should specify mass, volume or concentration.

(b) (i) 1 mark – Candidate loses 1 mark as the label on the X-axis is not

identical to the table and the scale on this axis is incorrect as the distance

from the origin to 10 is half the size it should be. Points are correctly

plotted and the line correctly drawn.

(ii) 0 marks

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(iii) 0 marks

(c) (i) 1 mark

(ii) 1 mark – The wording conveys that there are more yeast cells when SPF

15 is used.

(iii) 1 mark

Question 4


(a) 1 mark

(b) 0 marks – Answer does not indicate lowering of activation energy.

(c) 0 marks

(d) 1 mark

(e) 0 marks

Question 5


(a)(i) 0 marks

(ii) 0 marks

(b) 1 mark

(c) 3 marks – ‘But for a long period of time’ refers to contraction.

Question 6


(a)(i) 0 marks

(ii) 1 mark

(iii) 1 mark

(b) 0 marks

8

Question 7


(a) 1 mark

(b) 1 mark

(c) 0 marks

(d) 1 mark – The internalisation answer does not indicate either persuasion or the

source of persuasion.

Question 8


(a) 1 mark

(b) 0 marks

(c) 1 mark

(d) (i) 0 marks

(ii) 0 marks

(iii) 0 marks

Question 9


(a) 0 marks

(b) 0 marks

(c) 0 marks

Question 10


(a) 1 mark

(b) 0 marks

(c) 1 mark

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Question 11


(a)(i) 1 mark – Answer does not indicate that it is capillaries which become more

permeable. In addition capillaries do not vasodilate.

(ii) 0 mark – Pathogens do not undergo apoptosis. Answer must indicate that it

is the infected cell which does this.

(b) 1 mark

Question 12


(a) 1 mark

(b) 0 marks

(c) 0 marks

(d) 0 marks – ‘great spike’ does not indicate the steepest part of the graph. It

suggests an increase followed by a decrease.

Question 13


(a)(i) 0 marks – the answer does not convey an equal mix of genders in each

group.

(ii) 1 mark

(iii) 1 mark

(b) 0 marks

(c) 1 mark

Question 14


(A)(i) 6 marks for mentioning points 1, 2, 3, 4, 6, 7 and 8.

(ii) 4 marks for mentioning points a, b, c, e, and f.

10

Total mark


11

Candidate 3


Question 1


(a) 1 mark

(b) 1 mark

(c) (i) 1 mark – The mark is awarded as placing stem cells into the area to repair

the tissue indicates that the area refers to the damaged muscle tissue.

(ii) 1 mark

Question 2


(a) 1 mark

(b) (i) 1 mark

(ii) 1 mark – Note the additional guidance indicates that a ‘shortened

polypeptide chain’ is correct if linked to stop codon in part (b)(i).

(c) 0 marks

(d) 2 marks – The sex-linked answer implies that it is the carrier female who

passes the condition to her son.

Question 3


(a) 1 mark – Quantity is too vague a term compared to volume, mass or

concentration of yeast. Type of UV used suggests using the same lamp.

(b) (i) 2 marks – Note the scale on the X-axis just uses half the graph paper.

(ii) 1 mark – Damage to a cell’s DNA indicates cell damage increasing.

(iii) 0 marks – Repeating the result is wrong. The answer must refer to

repeating the investigation / experiment.

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(c) (i) 0 marks

(ii) 0 marks

(iii) 1 mark

Question 4


(a) 1 mark

(b) 0 marks

(c) 1 mark

(d) 0 marks

(e) 1 mark – ‘Excess ATP not produced’ implies the ATP is not required.

Question 5


(a) (i) 1 mark

(ii) 0 marks

(b) 1 mark

(c) 3 marks

Question 6


(a)(i) 0 marks

(ii) 0 marks

(iii) 0 marks

(b) 0 marks

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Question 7


(a) 1 mark

(b) 1 mark

(c) 0 marks – candidate does not mention height squared.

(d) 1 mark – The marks for identification and internalisation are not awarded as

there is no mention in either answer of promoting or adopting a healthy lifestyle /

healthy diet / exercise. However, as indicated in the additional guidance, one

mark is awarded for correctly giving the idea of ‘people they admire’ and

‘reasoned arguments’.

Question 8


(a) 2 marks

(b) 1 mark

(c) 1 mark

(d) (i) 1 mark

(ii) 0 marks – candidate has not entered the units.

(iii) 0 marks

Question 9


(a) 0 marks

(b) 0 marks

(c) 1 mark – The first sentence is wrong. Cocaine does not inhibit breakdown

proteins, it inhibits reuptake proteins. The ‘build-up of dopamine at the

receptor site’ implies dopamine remains at the receptors.

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Question 10


(a) 0 marks

.

(b) 0 marks

(c) 1 mark

Question 11


(a)(i) 2 marks

(ii) 1 mark

(b) 1 mark – Phagocytes engaging pathogens by phagocytosis implies engulfing

pathogens.

Question 12


(a) 1 mark

(b) 0 marks

(c) 1 mark

(d) 1 mark

Question 13


(a)(i) 1 mark

(ii) 1 mark

(iii) 0 marks

(b) 0 marks – wrong answer continues at back of paper.

(c) 1 mark

15

Question 14


(B)(i) 5 marks for mentioning points 1, 2, 3, 5, 6 and 7.

(ii) 5 marks for mentioning points a, b, c, e, and g.

Total mark


16

Candidate 4


Question 1


(a) 1 mark

(b) 1 mark

(c) (i) 1 mark

(ii) 0 marks

Question 2


(a) 1 mark

(b) (i) 1 mark – Specific description of a gene mutation given (deletion).

(ii) 1 mark

(c) 1 mark

(d) 2 marks

Question 3


(a) 2 marks

(b) (i) 2 marks –The cross at 0, 60 should be ignored as it is clearly part of a line

that the candidate has attempted to remove. Note – The candidate has also

drawn a graph at the end of the paper. However, this should be ignored

as the candidate has indicated not to use it.

(ii) 1 mark – Candidate gets this mark for clarifying the answer by saying ‘able

to grow from the surviving cells decreases’.

(iii) 1 mark

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(c) (i) 1 mark

(ii) 1 mark

(iii) 1 mark

Question 4


(a) 1 mark

(b) 1 mark

(c) 1 mark

(d) 0 marks – Candidate cannot be awarded this mark as answer must indicate

fructose-6-phosphate.

(e) 1 mark

Question 5


(a)(i) 2 marks

(ii) 1 mark

(b) 1 mark

(c) 2 marks – Marks awarded for ‘rapid contractions’ and ‘contains creatine

phosphate’. No mark is awarded for ‘short duration of activity’ as there is no

mention of contractions.

Question 6


(a)(i) 1 mark

(ii) 2 mark – ‘Cells are cultivated’ is the equivalent of cells being cultured.

(iii) 1 mark

(b) 1 mark

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Question 7


(a) 1 mark

(b) 1 mark

(c) 1 mark – Assume m = mass and h = height.

(d) 1 mark – No mark is awarded for identification as there is no indication that

the lifestyle is a healthy lifestyle.

Question 8


(a) 2 marks

(b) 1 mark

(c) 1 mark

(d) (i) 0 marks – although candidate has calculated 4·5 they have entered 5 in the

answer line.

(ii) 1 mark

(iii) 1 mark

Question 9


(a) 1 mark

(b) 1 mark

(c) 1 mark – There is no mention of proteins so candidate cannot get the cocaine

mark. Both correct statements refer to dopamine so candidate can only be

awarded one mark.

.

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Question 10


(a) 2 marks

(b) 0 marks

(c) 1 mark

Question 11


(a)(i) 2 marks – ‘Vasodilation of capillaries’ is wrong but candidate gains this

mark for indicating ‘enhanced capillary permeability’.

(ii) 1 mark

(b) 2 marks

Question 12


(a) 1 mark

(b) 1 mark

(c) 1 mark

(d) 1 mark

Question 13


(a)(i) 1 mark

(ii) 1 mark

(iii) 0 marks

(b) 1 mark

(c) 1 mark

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Question 14


(B)(i) 5 marks for mentioning points 1, 2, 3, 4, 6, and 7.

(ii) 5 marks for mentioning points a, b, d, f, g and h.

Total mark


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