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1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Humira Harvoni Revlimid Remicade Avastin Herceptin Lantus Enbrel Rituxan Prevnar Lyrica Neulasta Advair Copaxone Sovaldi Tecfidera Januvia Opdivo Truvada Crestor ( Adalimumab ) ( Ledipasvir And Sofosbuvir ) ( Lenalidomide ) ( Infliximab ) ( Bevacizumab ) ( Trastuzumab ) ( Insulin Glargine ) ( Etanercept ) ( Rituximab ) (Pneumococcal 7-Valent Conjugate) ( Pregabalin ) ( Pegfilgrastim ) ( Salmeterol And Fluticasone Propionate ) ( Glatiramer ) ( Sofosbuvir ) ( Dimethyl Fumarate ) ( Sitagliptin ) ( Nivolumab ) (Emtricitabine, Tenofovir Disoproxil) ( Rosuvastatin ) $16,078 Million $9,081 Million $6,974 Million $6,966 Million $6,715 Million $6,714 Million $6,057 Million $5,965 Million $5,765 Million $5,718 Million $4,966 Million $4,648 Million $4,321 Million $4,223 Million $4,001 Million $3,968 Million $3,908 Million $3,774 Million $3,566 Million $3,401 Million Immunology Infectious Diseases Oncology Immunology Oncology Oncology Diabetes Immunology Oncology Anti-Bacterial Neurological/Mental Disorders Blood Disorders Respiratory Disorders Neurological/Mental Disorders Infectious Diseases Neurological/Mental Disorders Diabetes Oncology Infectious Diseases Cardiovascular Diseases 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 Eliquis Gleevec Eylea Stelara Spiriva Gilenya Xarelto Symbicort Enbrel Soliris Victoza Novorapid/Novolog Botox Humalog Atripla Zetia Cialis Levemir Avonex Xarelto ( Apixaban ) ( Imatinib ) ( Aflibercept ) ( Ustekinumab ) ( Tiotropium ) ( Fingolimod ) ( Rivaroxaban ) ( Budesonide And Formoterol ) ( Etanercept ) ( Eculizumab ) ( Liraglutide ) ( Insulin Aspart ) ( Onabotulinumtoxina ) ( Insulin Lispro ) (Efavirenz, Emtricitabine, Tenofovir Disoproxil) ( Ezetimibe ) ( Tadalafil ) ( Insulin Detemir ) ( Interferon Beta-1A ) ( Rivaroxaban ) $3,343 Million $3,323 Million $3,323 Million $3,232 Million $3,175 Million $3,109 Million $3,104 Million $2,989 Million $2,910 Million $2,843 Million $2,806 Million $2,792 Million $2,786 Million $2,769 Million $2,605 Million $2,560 Million $2,472 Million $2,392 Million $2,314 Million $2,288 Million Blood Disorders Oncology Ophthalmology Immunology Respiratory Disorders Neurological/Mental Disorders Cardiovascular Diseases Respiratory Disorders Immunology Blood Disorders Diabetes Diabetes Urology Diabetes Infectious Diseases Cardiovascular Diseases Sexual Health Diabetes Neurological/Mental Disorders Cardiovascular Diseases 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 Alimta Xtandi Orencia Zytiga Invega Janumet Gardasil/Gardasil 9 Triumeq Ibrance Aranesp Nexium Vyvanse Tysabri Stribild Prezista Lucentis Imbruvica Perjeta Sprycel Lipitor ( Pemetrexed ) ( Enzalutamide ) ( Abatacept ) ( Abiraterone Acetate ) ( Paliperidone ) ( Metformin And Sitagliptin ) ( HPV Vaccine ) ( Abacavir, Dolutegravir, Lamivudine ) ( Palbociclib ) ( Darbepoetin Alfa ) ( Esomeprazole ) ( Lisdexamfetamine ) ( Natalizumab ) (Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Disoproxil) ( Darunavir ) ( Ranibizumab ) ( Ibrutinib ) ( Pertuzumab ) ( Dasatinib ) ( Atorvastatin ) $2,283 Million $2,279 Million $2,265 Million $2,260 Million $2,214 Million $2,201 Million $2,173 Million $2,151 Million $2,135 Million $2,093 Million $2,032 Million $2,014 Million $1,964 Million $1,914 Million $1,851 Million $1,835 Million $1,832 Million $1,828 Million $1,824 Million $1,758 Million Oncology Oncology Immunology Oncology Neurological/Mental Disorders Diabetes Oncology Infectious Diseases Oncology Blood Disorders Gastrointestinal Disorders Neurological/Mental Disorders Neurological/Mental Disorders Infectious Diseases Infectious Diseases Ophthalmology Oncology Oncology Oncology Cardiovascular Diseases 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 Epclusa Simponi Tasigna Lovenox Eylea Prograf Actemra Sandostatin Proquad Plavix Prolia Sensipar Hepatitis C Franchise Viagra Human Insulins Xgeva Viekira Pak Afinitor/Votubia Forteo Restasis ( Sofosbuvir And Velpatasvir ) ( Golimumab ) ( Nilotinib ) ( Enoxaparin ) ( Aflibercept ) ( Tacrolimus ) ( Tocilizumab ) ( Octreotide ) (MMRV Vaccine) ( Clopidogrel ) ( Denosumab ) ( Cinacalcet ) ( Daclatasvir ) ( Sildenafil ) ( Insulin ) ( Denosumab ) ( Ombitasvir/Paritaprevir/Ritonavir ) ( Everolimus ) ( Teriparatide ) ( Cyclosporine ) $1,752 Million $1,745 Million $1,739 Million $1,734 Million $1,723 Million $1,695 Million $1,680 Million $1,646 Million $1,640 Million $1,637 Million $1,635 Million $1,582 Million $1,578 Million $1,564 Million $1,553 Million $1,529 Million $1,522 Million $1,516 Million $1,500 Million $1,488 Million Infectious Diseases Immunology Oncology Blood Disorders Ophthalmology Immunology Immunology Oncology Infectious Diseases Cardiovascular Diseases Bone Health Hormonal Disorders Infectious Diseases Sexual Health Diabetes Oncology Infectious Diseases Oncology Bone Health Immunology 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 Genvoya Xolair Pradaxa Novomix/Novolog Mix Haemophilia Rituxan Complera Invokana Keytruda Lucentis Isentress Aubagio Humulin Pomalyst Epogen Remicade Velcade Imbruvica Kogenate Norditropin (Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Alafenamide) ( Omalizumab ) ( Dabigatran Etexilate ) ( Biphasic Insulin Aspart ) (Recombinant Human Coagulation Factor Viia) ( Rituximab ) (Rilpivirine, Emtricitabine, Tenofovir Disoproxil Fumarate) (Canagliflozin/Canagliflozin, Metformin HCl) ( Pembrolizumab ) ( Ranibizumab ) ( Raltegravir ) ( Teriflunomide ) ( Insulin Isophane ) ( Pomalidomide ) ( Epoetin Alfa ) ( Infliximab ) ( Bortezomib ) ( Ibrutinib ) ( Antihemophilic Factor (Recombinant) ) ( Somatropin ) $1,484 Million $1,483 Million $1,468 Million $1,467 Million $1,466 Million $1,462 Million $1,457 Million $1,407 Million $1,402 Million $1,392 Million $1,387 Million $1,373 Million $1,366 Million $1,311 Million $1,282 Million $1,268 Million $1,252 Million $1,251 Million $1,236 Million $1,228 Million Infectious Diseases Immunology Blood Disorders Diabetes Blood Disorders Oncology Infectious Diseases Diabetes Oncology Ophthalmology Infectious Diseases Neurological/Mental Disorders Diabetes Oncology Blood Disorders Immunology Oncology Oncology Rare Diseases Hormonal Disorders 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 Velcade Tradjenta Galvus Baraclude Viread Tivicay Entyvio Acthar Latuda Vytorin Cosentyx Mirena Procrit Activase/TNKase Sutent Cubicin Vesicare Diovan Sustiva Pulmicort ( Bortezomib ) ( Linagliptin ) ( Vildagliptin ) ( Entecavir ) ( Tenofovir Disoproxil ) ( Dolutegravir ) ( Vedolizumab ) ( Corticotropin ) ( Lurasidone ) ( Ezetimibe And Simvastatin ) ( Secukinumab ) ( Levonorgestrel ) ( Epoetin Alfa ) ( Alteplase/Tenecteplase ) ( Sunitinib ) ( Daptomycin ) ( Solifenacin ) (Hydrochlorothiazide And Valsartan) ( Efavirenz ) ( Budesonide ) $1,224 Million $1,196 Million $1,193 Million $1,192 Million $1,186 Million $1,182 Million $1,167 Million $1,160 Million $1,158 Million $1,141 Million $1,128 Million $1,106 Million $1,105 Million $1,097 Million $1,095 Million $1,087 Million $1,081 Million $1,073 Million $1,065 Million $1,061 Million Oncology Diabetes Diabetes Infectious Diseases Infectious Diseases Infectious Diseases Anti-Inflammatory Autoimmune Disorders Neurological/Mental Disorders Cardiovascular Diseases Immunology Sexual Health Blood Disorders Cardiovascular Diseases Oncology Anti-Bacterial Urology Cardiovascular Diseases Infectious Diseases Respiratory Disorders 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 Yervoy Leuprorelin Otezla Premarin Micardis Tarceva Tracleer Orkambi Renagel/Renvela Ventolin Abraxane Norvasc Exjade Infanrix, Pediarix Cymbalta Xeljanz Trulicity Exforge Nexavar Singulair ( Ipilimumab ) ( Leuprorelin ) ( Apremilast ) ( Conjugated Estrogens ) ( Telmisartan ) ( Erlotinib ) ( Bosentan ) ( Lumacaftor/ Ivacaftor ) (Sevelamer Hydrochloride, Sevelamer Carbonate) ( Albuterol ) ( Paclitaxel Protein-Bound ) ( Amlodipine ) ( Deferasirox ) (Diphtheria, Tetanus Acellular, Pertussis) ( Duloxetine ) ( Tofacitinib ) ( Dulaglutide ) ( Amlodipine And Valsartan ) ( Sorafenib ) ( Montelukast ) $1,053 Million $1,050 Million $1,017 Million $1,017 Million $1,017 Million $1,014 Million $1,010 Million $980 Million $977 Million $973 Million $973 Million $962 Million $956 Million $954 Million $931 Million $927 Million $926 Million $926 Million $922 Million $915 Million Oncology Oncology Dermatology Sexual Health Cardiovascular Diseases Oncology Cardiovascular Diseases Respiratory Disorders Urology Respiratory Disorders Oncology Cardiovascular Diseases Oncology Vaccines Neurological/Mental Disorders Immunology Diabetes Cardiovascular Diseases Oncology Respiratory Disorders 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 Reyataz Risperdal Concerta Strattera Abilify Micardis Chantix Brilinta Myrbetriq Farxiga Xolair Faslodex Opsumit Kadcyla Lupron Letairis Zoladex Cerezyme Lialda Flovent ( Atazanavir ) ( Risperidone ) ( Methylphenidate ) ( Atomoxetine ) ( Aripiprazole ) ( Telmisartan ) ( Varenicline ) ( Ticagrelor ) ( Mirabegron ) ( Dapagliflozin ) ( Omalizumab ) ( Fulvestrant ) ( Macitentan ) ( Trastuzumab Emtansine ) ( Leuprolide Acetate ) ( Ambrisentan ) ( Goserelin Acetate ) ( Imiglucerase ) ( Mesalamine ) ( Fluticasone Propionate ) $912 Million $893 Million $863 Million $855 Million $855 Million $843 Million $842 Million $839 Million $839 Million $835 Million $835 Million $830 Million $823 Million $823 Million $821 Million $819 Million $816 Million $793 Million $792 Million $790 Million Infectious Diseases Neurological/Mental Disorders Neurological/Mental Disorders Neurological/Mental Disorders Neurological/Mental Disorders Cardiovascular Diseases Neurological/Mental Disorders Cardiovascular Diseases Renal Disorders Diabetes Respiratory Disorders Oncology Cardiovascular Diseases Oncology Oncology Cardiovascular Diseases Oncology Rare Diseases Anti-Inflammatory Respiratory Disorders 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 Avodart Tamiflu Betaseron Nuvaring Breo Ellipta Myozyme Simponi Neupogen Synthroid Lamictal Esbriet Hepatitis Toprol-XL Seroquel XR Cellcept Celebrex Pristiq Synagis Creon Votrient ( Dutasteride ) ( Oseltamivir ) ( Interferon Beta-1B ) (Ethinyl Estradiol And Etonogestrel) ( Fluticasone Furoate And Vilanterol ) ( Alglucosidase Alfa ) ( Golimumab ) ( Filgrastim ) ( Levothyroxine ) ( Lamotrigine ) ( Pirfenidone ) ( Vaccine ) ( Metoprolol ) ( Quetiapine ) ( Mycophenolate Mofetil ) ( Celecoxib ) ( Desvenlafaxine ) ( Palivizumab ) ( Pancrelipase ) ( Pazopanib ) $787 Million $786 Million $778 Million $777 Million $769 Million $769 Million $766 Million $765 Million $763 Million $761 Million $760 Million $746 Million $737 Million $735 Million $734 Million $733 Million $732 Million $730 Million $730 Million $729 Million Urology Infectious Diseases Neurological/Mental Disorders Sexual Health Respiratory Disorders Rare Diseases Immunology Blood Disorders Hormonal Disorders Neurological/Mental Disorders Idiopathic Pulmonary Fibrosis Vaccines Cardiovascular Diseases Neurological/Mental Disorders Immunology Bone Health Neurological/Mental Disorders Respiratory Disorders Rare Diseases Oncology 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 Zyprexa Aprovel Kombiglyze Yasim Fabrazyme Benefix Pantoprazole Epzicom Kalydeco Augmentin Kyprolis Lumigan Toujeo Erbitux Zostavax Cinryze Pulmozyme Synagis Ranexa Androgel ( Olanzapine ) (Irbesartan/Irbesartan, Hydrochlorothiazide) ( Saxagliptin/Saxagliptin, Metoprolol ) (Drospirenone And Ethinyl Estradiol) ( Agalsidase Beta ) ( Coagulation Factor IX ) ( Pantoprazole ) ( Abacavir And Lamivudine ) ( Ivacaftor ) ( Amoxicillin And Clavulanate ) ( Carfilzomib ) ( Bimatoprost ) ( Insulin Glargine ) ( Cetuximab ) ( Zoster Vaccine Live ) ( Complement C1 Esterase ) ( Dornase Alfa ) ( Palivizumab ) ( Ranolazine ) ( Testosterone ) $725 Million $722 Million $720 Million $719 Million $714 Million $712 Million $709 Million $704 Million $703 Million $698 Million $692 Million $688 Million $688 Million $687 Million $685 Million $680 Million $678 Million $677 Million $677 Million $675 Million Neurological/Mental Disorders Cardiovascular Diseases Diabetes Sexual Health Rare Diseases Rare Diseases Gastrointestinal Disorders Infectious Diseases Respiratory Disorders Anti-Bacterial Oncology Ophthalmology Diabetes Oncology Infectious Diseases Cardiovascular Diseases Rare Diseases Respiratory Disorders Cardiovascular Diseases Hormonal Disorders Top 200 Pharmaceutical Products by Retail Sales in 2016 Compiled and Produced by the Njardarson Group (The University of Arizona): David T. Smith, Michael D. Delost, Haziq Qureshi, Jón T. Njarðarson
