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Comprehensive Geriatric Assessment in the 21 st Century Laurence Rubenstein, MD, MPH, FACP Professor & Chairman, Reynolds Dept of Geriatric Medicine University of Oklahoma College of Medicine June 2015 -- St. Gallen, Switzerland
Transcript
Page 1: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Comprehensive Geriatric Assessment

in the 21st Century

Laurence Rubenstein MD MPH FACP Professor amp Chairman Reynolds Dept of Geriatric Medicine

University of Oklahoma College of Medicine

June 2015 -- St Gallen Switzerland

Outline

US Aging Demographics Geriatric Imperative

Comprehensive Geriatric Assessment (CGA)

history purposes benefits

Geriatric care programs services financing

Future needs directions

The Geriatric Imperativerdquo

Increasing Elderly

Population

Vast Unmet Healthcare

Needs

13 US pop 65+

What is Special About Older Persons

bullMultiple interacting chronic diseases common

bullAtypical disease presentation

bullMany causes for functional dependency

bullMany sources for pain amp discomfort

bullDiminished reserve capacity

bullSpecial pharmacological considerations

bullSlower communication longer history

Comprehensive Geriatric Assessment

bull ldquoThe New Technology of Geriatricsrdquo

--Epstein Ann Intern Med 1987

bull Definition ldquoA Multidimensional

interdisciplinary diagnostic process to

identify care needs plan care and improve

outcomes of frail older peoplerdquo

Geriatric Assessment Purposes

Improve diagnostic accuracy

Optimize medical treatment

Improve medical outcomes

Improve function amp quality of life

Optimize living location

Minimize unnecessary service use

Arrange long-term case management

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 2: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Outline

US Aging Demographics Geriatric Imperative

Comprehensive Geriatric Assessment (CGA)

history purposes benefits

Geriatric care programs services financing

Future needs directions

The Geriatric Imperativerdquo

Increasing Elderly

Population

Vast Unmet Healthcare

Needs

13 US pop 65+

What is Special About Older Persons

bullMultiple interacting chronic diseases common

bullAtypical disease presentation

bullMany causes for functional dependency

bullMany sources for pain amp discomfort

bullDiminished reserve capacity

bullSpecial pharmacological considerations

bullSlower communication longer history

Comprehensive Geriatric Assessment

bull ldquoThe New Technology of Geriatricsrdquo

--Epstein Ann Intern Med 1987

bull Definition ldquoA Multidimensional

interdisciplinary diagnostic process to

identify care needs plan care and improve

outcomes of frail older peoplerdquo

Geriatric Assessment Purposes

Improve diagnostic accuracy

Optimize medical treatment

Improve medical outcomes

Improve function amp quality of life

Optimize living location

Minimize unnecessary service use

Arrange long-term case management

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 3: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

The Geriatric Imperativerdquo

Increasing Elderly

Population

Vast Unmet Healthcare

Needs

13 US pop 65+

What is Special About Older Persons

bullMultiple interacting chronic diseases common

bullAtypical disease presentation

bullMany causes for functional dependency

bullMany sources for pain amp discomfort

bullDiminished reserve capacity

bullSpecial pharmacological considerations

bullSlower communication longer history

Comprehensive Geriatric Assessment

bull ldquoThe New Technology of Geriatricsrdquo

--Epstein Ann Intern Med 1987

bull Definition ldquoA Multidimensional

interdisciplinary diagnostic process to

identify care needs plan care and improve

outcomes of frail older peoplerdquo

Geriatric Assessment Purposes

Improve diagnostic accuracy

Optimize medical treatment

Improve medical outcomes

Improve function amp quality of life

Optimize living location

Minimize unnecessary service use

Arrange long-term case management

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 4: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

What is Special About Older Persons

bullMultiple interacting chronic diseases common

bullAtypical disease presentation

bullMany causes for functional dependency

bullMany sources for pain amp discomfort

bullDiminished reserve capacity

bullSpecial pharmacological considerations

bullSlower communication longer history

Comprehensive Geriatric Assessment

bull ldquoThe New Technology of Geriatricsrdquo

--Epstein Ann Intern Med 1987

bull Definition ldquoA Multidimensional

interdisciplinary diagnostic process to

identify care needs plan care and improve

outcomes of frail older peoplerdquo

Geriatric Assessment Purposes

Improve diagnostic accuracy

Optimize medical treatment

Improve medical outcomes

Improve function amp quality of life

Optimize living location

Minimize unnecessary service use

Arrange long-term case management

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 5: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Comprehensive Geriatric Assessment

bull ldquoThe New Technology of Geriatricsrdquo

--Epstein Ann Intern Med 1987

bull Definition ldquoA Multidimensional

interdisciplinary diagnostic process to

identify care needs plan care and improve

outcomes of frail older peoplerdquo

Geriatric Assessment Purposes

Improve diagnostic accuracy

Optimize medical treatment

Improve medical outcomes

Improve function amp quality of life

Optimize living location

Minimize unnecessary service use

Arrange long-term case management

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 6: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Geriatric Assessment Purposes

Improve diagnostic accuracy

Optimize medical treatment

Improve medical outcomes

Improve function amp quality of life

Optimize living location

Minimize unnecessary service use

Arrange long-term case management

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 7: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Community Office Clinic

Home Visits

Hospital Special Care

Unit Consult Team

Nursing Home Special Beds

Admission Protocol

GERIATRIC ASSESSMENT WHERE

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 8: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

CGA The Hub of the Geriatric

Care System Rehab or Subacute

Unit

Day Care

Home Care

Respite

Case Mgmt

Nursing Home

Hospital

OPD

Community

CGA

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 9: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

CGA Measurable Dimensions

bull Physical health ndash Traditional history physical exam lab data problem list ndash Disease-specific severity indicators ndash Prevention practices (eg exercise asa vaccination)

bull Functional status ndash ADL amp IADL scales ndash Other functional scales (eg mobility quality of life)

bull Psychological health ndash Cognitive amp affective function scales

bull Socio-environmental parameters ndash Social networks amp supports ndash Economic adequacy ndash Environmental safety amp needs

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 10: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

GERIATRIC ASSESSMENT WHY

Much unreported treatable disease

and disability

Premature nursing home placement

Neglected rehabilitation

Excessive drug useiatrogenesis

Assessment improves outcomes

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 11: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Benefits of CGA Programs

Diagnosis

Function

Placement

Affect

Cognition

Medications

NH Use

Hospital Use

Costs

Mortality

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 12: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Randomized Trial of a Hospital Geriatric Evaluation amp Management Unit

Ref Rubenstein et al N Engl J Med 1984 3111664-70

Mortality (24 vs 48 at 1 yr)

NH Use (27 vs 47)

Rehosps (35 vs 50)

Costs ($22K vs $28K yr)

ADL (42 vs 24 at 1 yr)

Morale (42 vs 24 )

The Sepulveda GEM Study

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 13: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

In-Home CGA amp Case Management RCT Copenhagen (Br Med J 1984 2891522-1524)

Program

(N=285)

Controls

(N=287)

196

7

219

4884

30

16

35

261

10

271

6442

60

10

23

P

3-Year Mortality

NH Admissions

Hospital Admissions

Hospital Bed Days

Emergency Dept Visits

Home Help Provision

Home Modifications

lt05

NS

lt01

lt01

lt05

lt05

lt05

Cost of program more than matched by savings

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 14: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Hospital GEM Programs Published RCTs Reference TypeTarg Significant Impacts

surv fct NHhosp$

surv LOS$(12)

none

survcog drugs

dx(surv)

survfct ( hosp)

fct(surv) NH

affect

none

surv readm

fct NHhosp$

fct NH LOS lab ($)

$ LOS

$ re-adm hosp

satis (surv)

fct satis

fct NH

Rubenstein 84 CA

Collard 85 MA

Allen 86 NC

Hogan 87 Can

Gilchrist 88 UK

Hogan 90 Can

Applegate 90 TN

Fretwell 90 RI

Harris 91 Aus

Thomas 91 NC

Melin 92 Swe

Powers lsquo92 TN

Naughton lsquo94 IL

Naylor lsquo949 PANY

Reuben lsquo95 CA

Karppi lsquo95 Fin

Landefeld lsquo95 OH

Ward++

Ward0

Cons0

Cons+

Ward+

Cons+

Ward++

Cons0

Ward0

Cons0

Cons+fu0

Ward++

Cons++

Cons+fu0

Cons+

Ward+

Ward0

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 15: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Outpatient GAPs Published RCTs Reference Typefu Significant Impacts

dxfct hosp

surv hosp$(NH)

surv(affect)

hosp$

none

(cog)

NHfalls

surv

(surv) NH(hosp)

survfct hosp

home-surv

fct process

fct NH

fct NH hosp $

surv fct satis

fctcog hosp $

Tullock 79 UK

Hendricksen 84 Den

Vetter 84 UK

Williams 87 NY

Sorensen 88 Den

Epstein 90 RI

Carpenter 90 UK

Vetter 92 UK

Hansen 92 Den

Pathy 92 UK

Hall lsquo94 Can

Fabacher lsquo94 CA

Stuck lsquo95 CA

Melin lsquo95 Swe

Engelhardt lsquo96 NY

Bernabei lsquo98 It

OPD ++

Home ++

Home ++

OPD 0

Home 0

OPD 0

Home ++

Home ++

Home ++

Home +

Home +

Home +

Home ++

Home ++

OPD +

Home ++

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 16: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

LOW

bullNon-targeted bullConsult only bullNo follow-up bullLower intensity

HIGH

bullWell-targeted bullClinical control bullFollow-up bullHigher intensity

IMPACTS FROM GAPs

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 17: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

CGA Program Meta-Analysis End-of-Study Summary of Findings (Stuck et al Lancet 1993)

GEMU IGCS HAS HHAS OAS Hosp Non-

hosp All-CGA

Mortality 25 NS 21 NS NS 19 17 18

Home 66 np 24 49 NS np 26 25

Function 72 NS NS NS NS np NS np

Cognition 100 71 -- NS NS 79 NS 41

Hosp Use NS NS np NS NS NS np 12

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 18: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Updated Cochrane Meta-analysis

Hospital CGA

Eliis G et al Cochrane DB Syst Rev 2011 Jul 6(7)CD006211

22 trials 6 countries N=10315

CGA pts more likely to be alive at home raquo at 6 mos OR 125 95 CI 111-142 p=0002

raquo at 12 mos OR 116 95 CI 104-128 p=003

CGA pts less likely to be raquo Institutionalized OR 79 CI 69-88 plt0001

raquo Dead or deteriorated OR 76 CI 64-90 p=001

Subgroup analysis favors inpatient wards

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 19: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

Hospital CGA Living at home at end of follow-up

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 20: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Ellis G et al CGA in hospitals meta-analysis of RCTs BMJ 2011

343d6553 doi 101136bmjd6553

Hospital CGA Death at Follow-up (OR 12 mos)

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 21: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Preventive Home Visit Program

Meta-Analysis Summary (Stuck et al 1999)

14 Studies (UK-7 USA-3 DK-3 NL-1)

All population-based gt65 (mostgt75)

Visit staff RN-5 HV-5 MD-1 SW-1 lay-2

Effects

Mortality (OR=88 plt05)

NH admissions (OR=84 p=05)

Functional decline (OR=82 p=11)

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 22: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Preventive Home Visit Program

Meta-Analysis (2) Covariant Analysis

Mortality Significant only for progs with

control deaths gt8year (OR=8 vs 10)

NH admission Significant only for progs

with gt4 visits (OR = 8 vs 10)

Functional decline Significant only for

progs with CGA (OR =4 vs 11)

(Stuck et al 1999)

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 23: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Targeting of Geriatric Assessment (Stuck Egger et al JAMA 2002 2871022-8)

Geriatric assessment according to risk groups

bullFor dependent higher risk older persons

tailored CGA amp follow-up programs

bullFor persons at medium risk aged gt=75

preventive home visits

bullFor persons at low risk aged gt=60

health risk appraisals

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 24: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Elderly Population Subgroups

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 25: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Caring for Elderly Subgroups

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 26: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

ScreeningTargetingCGA System-wide Strategies for Older Persons

All Old Persons

Frail amp

Hi-risk

Hosp

Periodic Screening

Periodic CGA Immediate CGA

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 27: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Does CGA Really Work

Why have some trials been negative

Insufficient sample size

Inadequate targeting

Suboptimal outcome measures

Non-implementation of CGA advice limited resources

non-adherence

Improved control group care academic center ldquo2nd-opinionsrdquo

improving geriatric care trends

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 28: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Thus CGA programs do improve care

processes and outcomes if done well and on

appropriate patients

But CGA needs to be streamlined and costs

minimized to enhance widespread use

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 29: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Improving Geriatric Assessment

Efficiency in the Office Target assessment to patient population

Use self-administered screening forms

Take advantage of hierarchical measures

Use observations amp key informants

Multiple visits where feasiblepreferable

Use available office staff as ldquoteamrdquo

Succinct guidelines for common problems

Printed summaries amp instructions

The ldquo20-minute visitrdquo is possible

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 30: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Screening Instruments Functional Status

bull Basic Activities of Daily Living (Katz) 2-3 min

bull Bathing Dressing Getting to toilet

bull Transferring Continence Feeding

bull Instrumental ADLs (Lawton) 2-3 min

bull Shopping Telephoning Preparing meals

Housekeeping Doing laundry Finances

Medications Transportation

bull Advanced ADLs 2-3 min

bull Patient-specific higher function (eg occupation

recreation community service world travel)

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 31: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Screening amp Assessment Instruments

Dementia

3-item recall 1-2 min

clock drawing 1-3 min

mini-mental state (30-item) 4-10 min

Depression

single question lt1 min ldquoDo you often feel sad or depressedrdquo

5-item GDS 1-2 min

15-item GDS 3-5 min

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 32: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Screening amp Assessment Instruments

Vision ndash Screening Question lt1 min

ldquoDo you have difficulty with driving TV reading or daily

activities because of your eyesight even while wearing

glassesrdquo

ndash Snellen chart (far vision) 1-2 mins

ndash Jaeger card (near vision) 1 min

Hearing ndash Whisper test 1 min

whisper 3 letters 1 foot from ear (fail if lt50 after 3 reps)

ndash W-A Audioscope 1-2 mins 40db (fail if unable to hear 1000hz or 2000hz tones)

ndash Hearing Handicap Inventory 2 min

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 33: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Screening amp Assessment Instruments

Malnutrition ndash Screening question 1 min

ldquoHave you lost 10 lbs in past 6 mos without tryingrdquo

ndash BMI (wt in kgheight in meters) 1 min

ndash MNA-short form 1-2 min

ndash Full MNA 5-9 min

Mobility ndash Fall question lt1 min

ldquoHave you fallen to the ground in the past yearrdquo

ndash Timed up-amp-go test 1-2 min

Rise from chair walk 20 ft turn walk back to chair and sit

down (fails if gt15 secs)

ndash Gait amp balance test (Tinetti) 2-3 min

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 34: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

History of CGAGEM Programs

1935-1975 1975-1995 1995-2015

Early concepts Refinement Mainstream

amp models amp testing integration

-UK workhouses

-Marjory Warren

-AGSBGSGSA

ldquophilosophiesrdquo

-GEM amp ACE units

-Home visit teams

-Consult services

-Improved ldquousual carerdquo

-Chronic disease

management model

Descriptive papers Controlled trials Meta-analyses

Multi-site trials Addrsquol meta-analyses

UK NHS

VA GRECCs

NIA CGA Conf lsquo83

NIH Consensus Conf lsquo87

AGS-SGIM-ACP reports lsquo88

Kellogg Intrsquol Conf lsquo88

UK NHS GP health chex lsquo90

IAG SOTA Conf ndash Italy lsquo94

Uniform CGA databases (eg MDS RAI)

Capitation managed care

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 35: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

What works What doesnrsquot work

bullHospital

-GEM units ++

-Gero-rehabortho ++

-ACE units +

bullHome-visit CGA amp fu ++

bullHospital

-Consult teams alone

bullOutpatient

-Screening alone

-CGA alone

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 36: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Newer Geriatric Care Models

bull ACE Units uarr fct uarr home at fu (Baztan BMJ 2009)

bull Geriatric EDs

bull Ortho-geriatric programs

bull Pre-operative CGA

bull Interface geri (p short hosp) NS (Conroy Age Ageing 2011)

bull Post-acute care fu programs

bull Geriatrics in ACOs (accountable care orgs)

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 37: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Reorganization of Care in US Healthcare Reform

1deg Care MDs

Spec MDs

Outpt Hosp Care

Inpt Hosp Care

LTACs Inpt Rehab

SNFs HHC Hospice Pal Care

Medical Home

Post-Acute Bundling

Acute care episode w Post Acute Bundling

Acute Care Bundling

Accountable Care Organizations

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 38: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

The US Healthcare System

Good resources

High technology

Active research

Choice of provider

Provider flexibility

Relatively high

provider income

Too expensive

Too high-tech

Duplication amp

inefficiency

Inequality

Coverage gaps

Non-planned

ADVANTAGES DISADVANTAGES

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 39: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

CGA Remaining Questions

What is are most effective CGA models

Which outcome can CGA most improve

What are key program elements

Who benefits most (Targeting criteria)

How can we make CGA most cost effective

How best to integrate CGA into care system

Will CGA benefits decrease as ldquostandardrdquo care for older persons improves

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 40: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Modeling elder healthcare through Education Service amp Research

The Donald W Reynolds Department of Geriatric Medicine

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 41: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

bull Initiated in 1997 at VAMC

bull Rapid growth after initial DW Reynolds grant in 1999 ndash Initial mission ldquoto provide premier education for future geriatric

leaders amp providers outstanding service to seniors amp cutting edge aging researchrdquo

ndash One of only 6 full departments of geriatric medicine

bull Currently gt60 FTEE actively involved in education research and clinical care

bull Visionmdashto build a state-wide system of geriatric clinical and educational excellence emanating from OUHSC grounded in an outstanding research program w global reputation amp collaborations

Donald W Reynolds Department of

Geriatric Medicine Brief History

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 42: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Donald W Reynolds Department of Geriatric Medicine Components

bull Education

bull Medical (students residents fellows CME)

bull Allied health (nursing pharmacy rehab et al)

bull Community outreach (OHAI)

bull Clinical care

bull Hospital outpatient NH home care

bull Research

bull Basic ndash ROCA

bull Translational applied clinical health services

E

R C

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 43: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Extra slideshellip

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 44: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Fried amp Hall JAGS 2008

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 45: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Preventive CGA visits for home-living

elders Half full or half empty Systematic analysis Haastregt et al (BMJ 2000)

discrepancies ldquono evidencerdquo

Meta-Analysis Elkan et al (BMJ 2001) pooled effect

highly significant ldquohigh level of evidencerdquo

Stuck et al (JAMA 2002 2871022-8) meta-

analysis w meta-regression

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 46: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Systematic analysis of 18 trials

with meta-regression analyses

Hypothesized co-variates influencing

outcomes

- targeting independent older persons (EIGER study)

- long-term intervention follow-up (Lancet meta-analysis)

- use of intense multidimensional CGA

Stuck Egger et al JAMA 2002 2871022-8

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 47: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

0Soslashrensen (1988)

1 05 (085 to 130)Overal l (95 CI)

4Vetter (1992)

4van Haastregt (2000)

0Hebert (2001)

0Newbury (2001)

5Gunner-Svensson (1984)

090 (075 to 107)Overal l (95 CI)

85Carpenter (1990)

78Tinetti (1994)

75Stuck (2000)

01 02 05 1 2 5 10

12van Rossum (1993)

12Stuck (1995)

066 (048 to 092)Overal l (95 CI)

12Hendriksen (1984)

9Pathy (1992)

0 to 4 follow up visits No of visits

5 to lt 9 follow up visits

gt 9 follow up visits

Risk ratio

Risk of nursing home admission

Stuck et a l JAMA 2002

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 48: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Risk ratio

01 02 05 1 2 5 10

Multidimensional assessment

and follow up

van Haastregt (2000)

Fabacher (1994)

Hebert (2001)

Stuck (2000)

Stuck (1995)

Tinetti (1994)

McEwan (1990)

Soslashrensen (1988)

Newbury (2001)

van Rossum (1993)

Pathy (1992)

Clarke (1992)

Vetter (1992)

Carpenter (1990)

Vetter Powys (1984)

Vetter Gwent (1984)

No multidimensional assessment

and follow up

076 (064 to 091)Overal l (95 CI)

101 (092 to 111)Overal l (95 CI)

Figure 3 Stuck et al JAMA 2002

Risk of functional status decline

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 49: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

New studies published after meta-

analyses example 1

Cohen HJ al A controlled trial of inpatient and outpatient geriatric evaluation and management (N Engl J Med 2002 346 905 Med Care 2006 44 91)

11 VA centers with established geriatric assessment programs

Frail hosp older persons patients of geriatric program excluded

RCT w cross-over factorial design 1-yr follow-up

UCIP-UCOP (N=348)

UCIP-GEMC (N=346)

GEMU-UCOP (N=348)

GEMU-GEMC (N=346)

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 50: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Results at one-year follow-up (Cohen 2002 Schmader 2004 Phibbs 2006)

Survival

UCIP-UCOP 787

UCIP-GEMC 789 ns

GEMU-UCOP 787 ns

GEMU-GEMC 772 ns

Significant effects

GEMU uarr ADL darr NH adm amp days uarr Rx qual

GEMC uarr mental health darr drug reactions

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 51: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Limitations of the Cohen trial

raquo Factorial crossover design (possible effect on

processmdashteam did not know if they would be

following their patients)

raquo All sites with established high-quality geriatric

care programs (control care better than usual)

raquo Central control may have affected local team

processes (more complex than co-op drug

studies)

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 52: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

New studies published after

meta-analyses example 2

Saltvedt et al Reduced mortality in treating acutely

sick frail older pts in a GEM unit JAGS 2002

50792-8 (Norwegian RCT)

Acute pts gt75 randomized to GEMU or general

medicine wards in Univ of Trondheim Hosp

Mortality GEMU GIM P 3 mo

12 27 004 6 mo 16

29 02 12 mo 28 34 06

No data reported on other outcomes

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 53: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

CGA is effective in improving

many important outcomes

BUT

How can it be made more

practical or streamlined

to fit better within

todays medical reality

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 54: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Increasing CGA in Todays Reality Proposals

bull Multi-level targeting

screening rarr casefinding rarr CGA

bull Streamlined CGA approach

bull Recapturing cost savings

bull Integrated follow-up case-management system

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 55: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Geriatric Ambulatory Care Keys to Success

Comprehensive assessment

Interdisciplinary team approach

Provider continuity

Case management amp follow-up

Home support system phone contacts

meals-on-wheels home visits etc

Enthusiasm

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 56: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Hospital GEM Units Types Acute care units

most costly amp intensive handles ldquooutliersrdquo MD or RN run

Subacute care units longer LOS team care CGA amp rehab

Rehabilitation units stroke orthopedic or general rehab

Mixed units efficient space use swing beds issues of identity amp

balance

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 57: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Advantages of the Home Visit for

Geriatric Assessment

Observation of function at home

Observe environment access safety

Nutritional adequacy

Medication inventory

Social supports amp interactions

Elder abuse risks

Needs for adaptive equipment

Homemaker needs

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 58: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Key Observations During the

Home Visit Examples

Garden well tended

Entriesexits accessible

Refrigerator food quantity amp quality

Medicines polypharmacy current

Safety water temp smoke alarm floor

hazards (cords rugs clutter) rails

(bathroom stairways)

General temperatureinsulation

cleanliness lighting

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 59: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

1 in 12 8

1 in 5 20

US Population Growth

1 in 8

12

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 60: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

The Irsquos of Geriatrics

Instability (falls)

Incontinence

Intellectual impairment (dementia)

Iatrogenesis (polypharmacy)

Incoherence (delirium)

Insulin resistance (diabetes)

Immobility

Irritability (depression)

Inanition (malnutrition frailty)

Impoverishment

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 61: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

The whole world is aging

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 62: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Life spans in developed countries have risen dramatically

689 692

675 665

691

660

639

773 783 786

794 797 800

819

60

65

70

75

80

85

US UK Germany France Canada Italy Japan

Years

1950-1955 2000-2005

Life Expectancy at Birth by Country

Source UN (2005)

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 63: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Changing Mortality Causes

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 64: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

435

400

8575

5543

2920 17

0

50

100

150

200

250

300

350

400

450

500

Tobacco Poor dietinactivity

Alcohol Microbial agents

Toxic agents Motor Vehicle Firearms Sexual behavior

Illicit drug use

(Tho

usand

s)

Actual Causes of US Death - 2000

Mokdad AH Marks JS Stroup DF Gerberding JL Actual causes of death in the United States 2000 JAMA

20042911238-1245

Modifiable Causes of US Deaths ndash 2000

44 of All Deaths

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 65: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Hospital Use Increases with Age Annual US Hospital Discharges per 100 persons 1991

0

5

10

15

20

25

30

35

40

45

15-44

45-64

65-74

75+

Data from Health United States 1992 USPHS

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 66: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Hospital Discharge Locations of Discharges by Age Males 1987 US Data (NCHS 1993)

0

10

20

30

40

50

60

70

80

90

Home NH Died

55-64

65-74

75-84

85+

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 67: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Physician Visits uarrwith Age Mean noyr 2003-4 (NCHS 2006)

0

1

2

3

4

5

6

7

8

9

Males Females

45-54

55-64

65-74

74+

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 68: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Health Service $ uarrwith Age Per capita expenditures in $1000s 1987 US Data (NCHS 1993)

0

1

2

3

4

5

6

7

8

9

65-69 70-74 75-79 80-84 85+

Other

NHs

MDs

Hospitals

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 69: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Health Care Expenditures

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 70: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Functional Limitations

ADL Bathing dressing eating transfering walking toileting IADL Telephone housework meal prep shopping managing money

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 71: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Per Capita Health Spending in 2006

Source McKinsey Global Institute and NEJM 2009

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 72: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Percent Health Care of GDP 2006

data from WHO httpwwwwhointen

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 73: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Why is US Healthcare So Costly

bull Technology emphasis

bull Higher prices and wages

bull Price insensitivity amp supply-driven incentives (ldquofee for servicerdquo)

bull Valuesculture

bull Supplemental insurance

bull Inefficiency amp lack of care coordination

bull Poor lifestyle choices

bull Fear of litigation (ldquodefensive medicinerdquo)

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 74: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Geriatrics Founders amp Leaders

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 75: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Source ADGAP Longitudinal Study of Training and Practice in Geriatric Medicine Available at wwwADGAPstudyucedu Accessed April 8 2008

11423 11121

2412

4089

5940

8824

10858 10530

10215 9915 9701

9474 9263

8279

7128 7138 6875

7735 7420

7976 7762

8354 8143

8824 8279

5940

4089

2412

0

2000

4000

6000

8000

10000

12000

1988 1990 1992 1994 1996 1998 1999 2000 2001 2002 2003 2004 2005 2006

Cumulative Certificates awarded Currently Certified Geriatricians

Number of Geriatricians

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 76: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

GSA to Co-host The 2017 International Association of

Gerontology amp Geriatrics (IAGG) World Congress

Save the Date

July 23-27 2017

Moscone Center

San Francisco California

ldquoGlobal Aging and Health Bridging Science Policy and Practicerdquo

Web site launches June 2013

Visit iagg2017org and sign up to receive future IAGG2017 news

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 77: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Brief Timeline of US Geriatrics

Current Scene

7200 Certified Geriatriciansmdashtoo few Universal health insurance (Medicare)

LTC NH homecare daycare New Rx benefit Hospice coverage

Prevention benefits PACE programs

Developmental Phase

1974 NIA 1975 VA GRECCs 1978 IOM report ldquoAging amp Med Educationrdquo 1978

VA geriatrics fellowships

1980s Recognition of geriatric syndromes amp CGA

1988 Geriatrics Board Certification

Early Days

1909 Dr Nascher coins term ldquogeriatricsrdquo 1914 publishes first text

1930s British take lead in developing field Marjory Warren describes her

successes in chronic hospitals

1939 GSA 1942 AGS 1946 J Gerontology 1953 JAGS

1964 Medicare

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition

Page 78: Comprehensive Geriatric Assessment in the 21st …. L. Rubenstein, Geriatric... · Comprehensive Geriatric Assessment in the 21st Century Laurence Rubenstein, MD, MPH, FACP Professor

Newer Meta-analysis Hosp CGA Programs (Ellis amp Langhorne Brit Med Bull 2005 7145)

uarr hospital CGA RCTs (13 rarr 20) 10 GEMU 10 IGCS

End-of-study mortality became NS OR = 095 (95 CI 087-105 n=10427)

Living at home 6 mo 12 mo GEMU 180 (13-25) 168 (12-24)

GEMU + IGCS 126 (104-15) 147 (11-19)

4 extra pts alive amp at home per 100 treated (95 CI 1-7)

No new data on uarrfunction amp uarrcognition


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