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Concept of Death Dr Rizwan

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    CONCEPT OF DEATH CONCEPT OF DEATH

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    Death is the end of dying.

    It is a process rather than an event, except insituations where death occur instantaneously

    like bomb blast, crushing of head in Roadside accidents.

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    S ection 2b of the Registration of Births andDeaths Act defines death as

    Permanent disappearance of allevidence of life at any time after live birth hastaken place

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    U nited S tate (Blacks) Dictionary of Lawdefines death as:

    The cassation of life, the ceasing toexist

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    S hapiro (1969) defines death asThe irreversible lose of the properties of

    living matter

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    Rantoul and S mith (1973):- C omplete and persistent cessation of

    respiration and circulation

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    Death is not a moment

    buta Continuous Process

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    C LASS IFIC ATION OF DEATH

    B iologically

    Death occurs in bits & pieces

    Moment of start of this disintegration,cannot be ascertained

    Declaring------Death - has become more difficult

    Since 1967-Dec

    (First human heart transplant was successfully carried)

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    The living body depends upon the integrity of three principals, interdependent upon eachother, these systems are

    1) Respiration2) C irculation3) Enervation

    The failure of one of themWill cause failure of other twoThis lead to the death of

    an individual.

    C irculation

    Enervation

    Respiration

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    There are two phases of death1. Extinction of the personality is the immediate

    sign of vital processOR

    S omatic Death2. Progressive disintegration of the body tissue

    ORMolecular Death / C ellular Death

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    BRAIN

    HEART

    LU NG

    TRIPOD of LIFE

    (Atria mortis)

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    TWO STAGES1) Somatic Death (Soma- B ody)

    Irreversible loss of integrating and co-coordinating functions of the organs as awhole is labeled as Somatic Death.

    It is the complete and persistent

    loss of coordinated functioning of tripod of life i.e stoppage of Functioning - and failure to return

    a) B rain

    b) Heartc) Lung

    BRAIN

    HEART

    LU NG

    TRIPOD of LIFE(Atria mortis)

    Deaths protocolof entry

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    Same is also called

    Systemic

    Clinical

    Legal

    Death

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    II. Molecular DeathIt is the death of individual organs and

    tissues (which persisted individually after

    somatic death)

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    In 1967- Single Organ, Shifted from a dead

    unit to another living unit.

    During interval it was kept alive to avoid

    molecular death.

    Till it was shifted to already prepared

    body Ready to receive Heart of Dead

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    Time Interval between Somatic &

    Molecular stages

    Heart Survives For 60 minutesLiver Survives for 15 minutes

    Kidney Survives for 45minutesCornea Survives for 6-24 HoursB lood Survives for 6 HoursB one Marrow Survives for 6 Hours

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    DEATHMeans an irreversible cessation of the entire

    function of brain stem.

    BRAIN DEATHMeans irreversible loss of brain and brain

    stem functions simultaneously,

    DONORMeans a person who donates any part of his

    body, organ. tissue or cell;

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    Criteria for determining permanent nonCriteria for determining permanent nonfunctioning of the brain.functioning of the brain.I. U nreceptivity and unresponsivetyII. No movements and breathing

    III. No reflexes AND

    Flat isoelectric encephalogram EEG(confirmatory test)

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    Philadelphia Protocol, 1969:1. lack of responsiveness.2. absence of spontaneous breathing3. no muscular movements, flaccidity4. Reflexes and Responses:

    (a) pupils, (b) corneal reflex, (c) pressure response, (d)no ocular response to ice water, (e) no superficial or deep tendon reflexes, (f) no planter response.

    5. Falling arterial pressure6. E C G for 5mins repeated every 30 mins for 6 hrs

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    Harvard Criteria:

    U nreceptively and unresponsivelyNo movements

    Apnea Absence of reflexes Absence of E C G

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    B rain death is declared when there is1. Permanent fixed bilateral dilatation of

    pupils.

    2. Absent all nerve reflexes3. Cessation of respiration

    (without aids.)4. Cessation of cardiac activity

    (COMPLETE FLAT ECG)

    DIAGNOSIS OF DEATH

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    D/D of Death

    1. Suspended animation

    2. B arbiturate poisoning

    3. Electrocution4. Drowning

    5. Hypothermia

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    Immediate physical changes

    Loss of tripod of life Absence of brain functionLoss of muscle tone

    Onset of muscular flaccidity / primaryflaccidityLoss of reflexes

    Dropping of lower jawLoosness of limbsNo response to external stimuliC ooling of body

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    Cause of brain death /Manner of death

    Natural

    U nnatural

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    Natural

    Haemorrhage into brain tissue / CV A Apoplexy (rupture of vessel in to an organ) Aneurysm / embolism of cerebral vesselsC ystic tumor / abscess which may rupture intoventriclesC erebral haemorrhage

    S ubarachnoid haemorrhageEpilepsy (cont discharge of impulses)

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    Natural cont.

    C erebral thrombosis and subsequent infarctionC erebral embolism

    MeningitisTumor of brain producing pressureTumor of brain with sudden haemorrhageMetabolic disorders e.g. uraemiaC ardiovascular condition e.g MIRespiratory condition e.g Asthma, C OPD

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    U nnatural

    Accidental head injuries e.g. RTAHomicidal head injuries e.g. stab, lacerated,

    incised, firearmS uicidal head injuries e.g. firearm injuryPoisoning e.g. Opium, alcohol

    AsphyxiaS yncope

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    M ode of DeathM ode of Death

    1.1. Coma :Coma :- - failure of function of brainfailure of function of brain2.2. Syncope :Syncope :- - failure of function of heart failure of function of heart

    3.3. Asphyxia : Asphyxia :- - failure of function of respiratory failure of function of respiratory

    systemsystem

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    C oma:- failure of function of brain andirreversible damage to its vital centers

    Due toRaised I C P, due to injuries to or diseases of brain e.gmeningitisPoisons such as opioids and alcoholMetabolic disorders like U remia

    Post mortem :-oedema and congestion of brain and

    membranes

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    S yncope :- death due to failure of function of heart due to decrease flow of blood to brainand leading to hypoxia of brain.Due to

    Heart diseasesDiseases of bloodHemorrhage

    Poisoning due to digitalis, aconite, potassium.Postmortem findings:-V iscera appear pale and capillaries appear congested

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    SIGNS OF DEATH SIGNS OF DEATH ImmediateImmediateEarly Early LateLate

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    a.a.Insensibility and loss of voluntary Insensibility and loss of voluntary power to move. power to move. (Not a sure sign of death)

    It is the foremost sign but also occurs in:

    - Prolonged fainting- Vagal inhibition- Epilepsy- Electrocution

    - Drowning- Suspended Animation

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    b.b. Cessation of circulationCessation of circulation

    No heart beat for a continuous period of 5 minutes (with

    stethoscope - sure sign)

    Difficulty in - Feeble sounds- Thick Chest

    - Emphysema

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    c. Cessation of Respirationc. Cessation of Respiration

    i. No abdominal movement (Ant.wall)

    ii. No auscultation with stethoscope for 5 minutes

    iii. Mirror Test

    iv. Feather Test

    v. Glass water Test. (Winslows Test )

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    B . Early signs (molecular death)B . Early signs (molecular death)

    a. Cooling of body

    b. Eye changes

    c. Skin changesd. Post-mortem lividitye. Muscles changes Rigor Mortis

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    B . EARLY SIGNS B . EARLY SIGNS contcont

    a)a) Cooling Cooling of of body body :: (Algor (Algor M ortis)M ortis)I. During life: B alance of temperature is

    maintained i.e. Heat produced = Heat lossII. After death no heat production, so only heat

    loss.

    III.The heat loss is gradual.

    IV. This remarkable phenomenon was used tocalculate time since death.

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    b)b) Eye changesEye changes

    i. Permanent fixed bilateral dilatation of pupils.

    ii. Cornea becomes hazy & opaque

    iii. Corneal & Conjunctival reflexes are lostiv. Luster of cornea is lost.

    v. Eyes become sunken.

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    C) Skin changesC) Skin changes

    i. Skin becomes pale(more on non dependent

    parts

    ii. Skin elasticity is lostiii. Skin luster is lost

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    d)d) Post Post M ortem Lividity M ortem Lividity

    It is the staining or discoloration of skin and

    organs of a dead body due to accumulation of

    blood because of gravitation and arrest of

    circulation resulting in distension of toneless

    capillaries and veins of dependent parts.

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    DEVELOP M ENT OF LIVIDITY DEVELOP M ENT OF LIVIDITY After somatic or clinical death:-

    Circulation stopsB lood remains fluid for some hoursO 2 in blood (which is carried in loose

    combination with Hb) is still being suppliedto the tissue(till molecular death).

    No more pumping of blood by heartO 2 is gradually decreased & Hb is reduced

    (B lue colour)Due to gravity blood settles, directly in

    dependent areas of skin or viscerae

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    Putrefaction ( U ltimate fate of all living creatures.)It is the final stage of dissolution of the body tissue resulting in

    breaking down of complex organic body constituents intosimpler inorganic ones.Arrest of putrefaction.

    (Extra ordinary phenomenon)

    - Mummification- Adipocere formation

    C.C. Late signs Late signs

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    MUMMIFI CAT ION MUMMIFI CAT ION It It isis alsoalso aa modificationmodification of of putrefaction putrefaction

    process, process, whichwhich becomesbecomes arrested arrested and and body body

    tissuestissues undergoundergo mummificationmummification. .

    It It isis characterized characterized by by dehydrationdehydration of of body body

    tissuestissues and and visceraeviscerae after after deathdeath

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    ADIPO CERE (SA PONIFI CAT ION) ADIPO CERE (SA PONIFI CAT ION)

    It is a modification of process of

    putrefaction, which may become arrested and

    fatty tissue of body may get converted into fatty

    acids. It has the properties of fat and wax, so the

    name

    (Adipo - soft fat) (Cera - Wax)

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    Suspended animationSuspended animation(Apparent Death)(Apparent Death)HeartHeart beatbeat && respiratoryrespiratory movementsmovements areare notnotheardheard ordinarilyordinarily (as(as theythey areare atat aa veryvery lowlowpitchpitch..) )

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    I. Involuntary S uspended animation

    may occur in:Drowning casesNew bornAnesthesia

    ConcussionHeat StrokeProlonged illnessElectrocutionDeep Shock

    All may revive byresuscitation methods

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    II. V oluntary S uspended animationS .A

    Y ogis (Holding of B reath)

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