Contents of Volume 184

Number 1, 5 July 1985

Dairi, T., Inokuchi, K., Mizuno, T. and Mizushima, S., Positive Control of Transcription Initiation in Escherichia coli. A Base Substitution at the Pribnow Box Renders ompF Expression Independent of a Positive Regulator . . . .

Hess, J., Perez-Stable, C., Wu, G. J., Weir, B., Tinoco, I., Jr and Shen, C.-K. J., End- to-end Transcription of an Alu Family Repeat. A New Type of Polymerase-III- dependent Terminator and its Evolutionary Implication . .

Takebe, Y., Miura, A., Bedwell, D. M., Tam, M. and Nomura, M., Increased Expression of Ribosomal Genes During Inhibition of Ribosome Assembly in Escherichia coli . . . . . . . . .

Mayaux, J.-F., Fayat, G., Panvert, M., Springer, M., Grunberg-Manago, M. and Blanquet, S., Control of Phenylalanyl-tRNA Synthetase Genetic Expression. Site- directed Mutagenesis of the pheS, T Operon Regulat,ory Region in vitro .

Kitani, T., Yoda, K., Ogawa, T. and Okazaki, T., Evidence t,hat Discontinuous DNA Replication in Escherichia co2i is Primed by Approximately 10 to 12 Residues of RNA Starting with a Purine . . . . . . .

Expert-Bezancon, A. and Wollenzien, P. L., Three-dimensional Arrangement of the Escherichia coli 16 S Ribosomal RNA . . . . . . . .

Wollenzien, P. L., Murphy, R. F., Cantor, C. R., Expert-Bezancon, A. and Hayes, D. H., Structure of the Escherichia coli 16 S Ribosomal RNA. Psoralen Crosslinks and N-acetyl-N’-(p-glyoxylylbenzoyl)cystamine Crosslinks Detected by Electron Microscopy

Baker, T. S., Sosinsky, G. E., Caspar, D. L. D., Gall, C. and Goodenough, D. A., Gap Junction Structures. VII. Analysis of Connexon Images Obtained with Cationio and Anionic Negative Stains . . . . . . . .

von Heijne, G., Signal Sequences. The Limits of Variation . . . .

Romby, P., Giege, R., Houssier, C. and Grosjean, H., AnticodonAnticodon Interactions in Solution. Studies of the Self-association of Yeast or Escherichin coli tRNAAsp and of their Interactions with Escherichia coli tRNA”“’ . . . .

Westhof, E., Dumas, P. and Moras, D., Crystallographic Refinement of Yeast Aspartic Acid Transfer RNA . . . . . . . . .

Honzatko, R. B., Hendrickson, W. A. and Love, W. E., Refinement of a Molecular Model for Lamprey Hemoglobin from Petromyzon mar&us . . . . .

Leroy, J.-L., Broseta, D. and Gueron, M., Proton Exchange and Base-pair Kinetics of Poly(rA) . poly(rU) and Poly(r1) * poly(rC) . . . . .

Letter to the Editor

Ammon, H. L., Murphy, K. C., Chandrasekhar, K. and Wlodawer, A., Preliminary Crystallographic Study of an L-Asparaginase from Vibrio succinogenes .

Number 2,20 July 1985

Stroke, I. L. and Weiner, A. M., Genes and Pseudogenes for Rat U3A and U3B Small Nuclear RNA . . . . . . . . . . . . .

Margot, J. B. and Hardison, R. C., DNase I and Nuclease S, Sensitivity of the Rabbit fil Globin Gene in Nuclei and in Supercoiled Plasmids . .

1

7

23

31

45

53

67

81

99

107

119

147

16Fi

179

183

195

111

iv (:ONTENTS

Abremski, K. and Hoess, R., Phage Pl Cre-ZoxP Site-specific Recombination. Effects ot DNA Supercoiling on Catenation and Knotting of Recombinant, Products

Martin, P. F., Place, A. R., Pentz, A. and Sofer, W., IJGA Nonsense Mutation in the Alcohol Dehydrogenase Gene of Drosophila melanogaster .

Makino, K., Shinagawa, H. and Nakata, A., Regulation of the Phosphate Regulon of Escherichia coli K-12: Regulation and Role of the Regulatory Gene phoR . .

Amemura, M., Makino, K., Shinagawa, H., Kobayashi, A. and Nakata, A., Nucleot.ide Sequence of the Genes Involved in Phosphate Transport and Regulation of t’he Phosphate Regulon in Escherichia coli . .

Vengerov, Y. Y., Semenov, T. E., Streltsov, S. A., Makarov, V. L., Khorlin, A. A. and Gursky, G. V., Triple Rings: A New Type of Compact Structure of Circular DNA

Schirmer, T., Bode, W., Huber, R., Sidler, W. and Zuber, H., X-ray Crystallographic Structure of the Light-harvesting Biliprotein C-Phycocyanin from the Thermophilic Cyanobacterium Mastigocladus laminosus and its Resemblance to Globin Structures

Carter, D. C., Melis, K. A., O’Donnell, S. E., Burgess, B. K., Furey, W. F. Jr, Wang, B.-C. and Stout, C. D., Crystal Structure of Azotobacter Cytochrome cg at 2.5 A Resolution . . . .

Bennett, P., Starr, R., Elliott, A. and Offer, G., The Structure of C-protein and X-prot,ein Molecules and a Polymer of X-protein .

Katz, B. A., Ollis, D. and Wyckoff, H. W., Low Resolution Crystal Structure of Muconolactone Isomerase. A Decamer with a 5-fold Symmetry Axis . .

Shimada, J. and Yamakawa, H., Statistical Mechanics of DNA Topoisomers. The Helical Worm-like Chain . . . . .

Mitchinson, C. and Pain, R. H., Effects of Sulphate and Urea, on the Stability and Reversible Unfolding of P-Lact,amase from Staphylococcus aureus. Implications for the Folding Pathway of a-Laatamase .

Letters to the Editor Raftery, L. A. and Yarus, M., Site-specific Mutagenesis of Escherichia coli gltT Yields

a Weak, Glutamic Acid-inserting Ochre Suppressor .

Grange, T., GuCnet, C., Dietrich, J. B., Chasserot, S., Fromont, M., Befort, N., Jami, J., Beck, G. and Pictet, R., Complete Complementary DNA of Rat Tyrosine Aminotransferase Messenger RNA. Deduction of the Primary Structure of the Enzyme . . . . . . . .

Announcement . . . . .

Number 3, 5 August 1985

Lang, B. F., Ahne, F. and Bonen, L., The Mitochondrial Genome of the Fission Yeast Schizosaccharomyces pombe. The Cytochrome b Gene has an Intron Closely Related to the First Two Introns in the Saccharomyces ~0x1 Gene . .

Miiller, G., Scherer, G., Zentgraf, H., Ruppert, S., Herrmann, B., Lehrach, H. and Schlitz, G., Isolation, Characterization and Chromosomal Mapping of the Mouse Tyrosine Aminotransferase Gene . . . . . .

Kunes, S., Botstein, D. and Fox, M. S., Transformation of Yeast with Linearized Plasmid DNA. Formation of Inverted Dimers and Recombinant Plasmid Products

Yang-Yen, H.-F., Subrahmanyani, C. S., Cassidy, B. and Rothblum, L. I., Characterization of Rat Ribosomal DNA II. Identification of the Highly Repetitive DNA in the 3’ Non-transcribed Spacer . .

211

%%I

231

241

251

257

279

297

311

319

331

343

347

351

353

367

375

389

CONTENTS v

Yi, Q.-M., Rockenbach, S., Ward, J. E. Jr and Lutkenhaus, J., Structure and Expression of the Cell Division Genes ft.@, &A and ftsZ . . .

Collins, R. A. and Lambowitz, A. M., RNA Splicing in Neurospora Mitochondria. Defective Splicing of Mitochondrial mRNA Precursors in the Nuclear Mutant +1X-1 .

Crowtber, R. A., Padron, R. and Craig, R., Arrangement of t’he Heads of Myosin in Relaxed Thick Filaments from Tarantula Muscle . . .

Roe, J.-H., Burgess, R. R. and Record, M. T. Jr, Temperature Dependence of the Rate Constants of the Escherichia coli RNA Polymerase-AP, Promoter Interaction. Assignment of the Kinetic Steps Corresponding to Protein Conformational Change and DNA Opening . . . . .

Romby, P., Moras, D., Bergdoll, M., Dumas, P., Vlassov, V. V., Westhof, E., Ebel, J. P. and Giege, R., Yeast tRNAAsp Tert,iary Struct’ure in Solution and Areas of Interaction of the tRNA with Aspartyl-tRNA Synthetase. A Comparative Study of the Yeast Phenylalanine System by Phosphate Alkylation Experiments with Ethylnitroso- urea . . . . . . . .

Hulmes, D. J. S., Holmes, D. F. and Cummings, C., Crystalline Regions in Collagen Fibrils . . . . . . . . . . . . . .

Fujinaga, M., Delbaere, L. T. J., Brayer, G. D. and James, M. N. G., Refined Structure of a-Lytic Protease at 1.7 A Resolution. Analysis of Hydrogen Bonding and Solvent Structure . . . . .

Gilson, M. K., Rashin, A., Fine, R. and Honig, B., On the Calculation of Electrostatic Interactions in Proteins. . . . . . . .

Appendix: Electrostatic Forces in a Spherical Dielectric Cavity . . . .

Prouty, M. S., Schechter, A. N. and Parsegian, V. A., Chemical Potential Measurements of Deoxyhemoglobin S Polymerization. Determination of the Phase Diagram of an Assembling Protein . . . . . . . . . . .

Letters to the Editor Matsui, M., Oka, A., Takanami, M., Yasuda, S. and Hirota, Y., Sites of dnaA

Protein-binding in the Replication Origin of the Escherichia co& K-12 Chromosome

Walker, M., Knight, P. and Trinick, J., Negative Staining of Myosin Molecules

Milam, L. M., Electron Microscopy of Rotary Shadowed Vinculin and Vinculin Complexes . . . . . . . . . . .

399

413

429

441

455

473

479

503

515

517

529

535

543

Number 4,20 August 1985

Jubier-Maurin, V., Dod, B. J., Bellis, M., Piechaczyk, M, and Roizes, G., Comparative Study of the Ll Family in the Genus Mus. Possible Role of R.etroposition and Conversion Events in its Concerted Evolution . . . . .

Ainley, W. M., Macreadie, I. G. and Butow, R. A., varl Gene on the Mitochondrial Genome of Torulopsis glabrata . . . . .

Wood, R. D., Pyrimidine Dimers are not the Principal Pre-mutagenic Lesions Induced in Lambda Phage DNA by Ultraviolet Light . .

Borowiec, J. A. and Gralla, J. D., Supercoiling Response of the Zac ps Promoter in Vitro

Daniels, D. W. and Bertrand, K. P., Promoter Mutations Affecting Divergent Transcription in the TnZO Tetracycline Resistance Det,erminant .

Banville, D. and Williams, J. G., Developmental Changes in the Pattern of Larval jl-Globin Gene Expression in Xenopus laevis. Identification of Two Early Larval P-Globin mRNA Sequences . . . . .

547

565

577

587

599

611

vi CONTENTS

Yamaguchi, M., Izumimoto, M., Robson, R. M. and Stromer, M. H., Fine Structure of Wide and Narrow Vertebrate Muscle Z-lines. A Proposed Model and Computer Simulation of Z-line Architecture . . . .

Appendix: Yamaguchi, M., Hirai, Y., Hage, A., Kamisoyama, H. and Anderson, W. D., Small Square (SS) Net Structure of the Narrow Z-line . .

Khan, S., Meister, M. and Berg, H. C., Constraints on Flagellar Rotation

Appendix . . . . . . .

Han, S., Udvardy, A. and Schedl, P., Neurospora craSSa and S, Nuclease Cleavage in hsp 83 Gene Chromatin . . . . . .

Booy, F. P., Ruigrok, R. W. H. and van Bruggen, E. F. J., Electron Microscopy of Influenza Virus. A Comparison of Negatively Stained and Ice-embedded ParGcles

Walker, J. E., Fearnley, I. M., Gay, N. J., Gibson, B. W., Northrop, F. D., Powell, S. J., Runswick, M. J., Saraste, M. and Tybulewicz, V. L. J., Primary Structure and Subunit Stoichiometry of’ F,-ATPase from Bovine Mitochondria .

Tsukada, H. and Blow, D. M., Structure of a-Chymotrypsin Refined at 1.68 A Resolution

Hoffmann, W., Franz, J. K. and Franke, W. W., Amino Acid Sequence Microheterogeneities of Basic (Type II) Cytokeratins of Xenopus Zaevis Epidermis and Evolutionary Conservativity of Helical and Non-helical Domains .

Sancar, A., Franklin, K. A., Sancar, G. and Tang, M.-s., Repair of Psoralen and Acetyfaminofluorene DNA Adducts by ABC Excinuclease .

Letters to the Editor Ikeda, T., Asakura, S. and Kamiya, R., “Cap” on the Tip of Salmonella Flagella

Weaver, L. H., Rennell, D., Poteete, A. R. and Matthews, B. W., Structure of Phage p22 Gene 19 Lysozyme Inferred from its Homology with Phage T4 Lysozyme. Implications for Lysozyme Evolution . .

621

644

645

656

657

667

6ii

703

7 13

72.5

73.5

739

Index to Volume 184

ABC excinuclease repair of psoralen and acetylaminofluorene DNAtsdducts, 7%~

ABREMSKI. K. & HOESS, R., Phage Pl Cre-ZozP site-specific recombination. Effects of DNA supercoiling on catenation and knotting of recombinant products, 211

Acetylaminofluorene DNA adducts, repair by ABC excinuclease. 725

Adducts, psoralen and acetylaminofluorene DNA, repair by AN! excinuclease. 725

AHNE, F. (see also LANG, Il. F.), 353 AINLEY, W. M., MACREADIE, I. Q. & BUTOW, R. A., varl gene on

the mitochondrial genome of Torulopsis glabrata, 565 Alcohol dehydrogenase gene of Drosophila melanogaster. UGA

nonsense mutation, 221 Alu family repeat, end-to-end transcription; a new type of

polymerase-Ill-dependent terminator and its evolutionary implication, 7

AMEMVRA. M., MAKINO, K., SHINAGAWA, H., KOBAYASHI, A. & NAKATA, A.. Nurleotide sequence of the genes involved in phosphate transport and regulation of the phosphat,e regulon in Eseherichia coli, 241

Amino acid sequence microheterogeneities of basic (type II) cytokcratins of Xenopus laevis epidermis and evolutionary conservativity of helical and non-helical domains, 713

ANMON. H. L.. MURPHY. K. (1.. CHANDRASEKHAR, K. & WI,OUAWER, A.. Preliminary crystallographic study of an L-asparaginase from ribrio succiwgenes, 179

ANI)ERSON. W. D. (see also YAMAGUCHI, M.), 644 Anticodon-ant&don interactions in solution. Studies of the self-

association of veast or Escherichia coli tRNAASP and of their interactions with Eschwichia coli tRNA”*‘. 107

ASAKURA, S. (see also IKEDA, T.), 735 L-Asparaginase from Vibrio succincgen~s, preliminary

crytallographir study. 179 Aspartrc aoid tRNA. yeast. crystallographic refinement, 119 Aspartyl-tRNA svnthetasr interaction with tRNA, and yeast

tRNAASp tertiary structure in solution. Comparative study of yeast phenylalanine system by phosphate alkylation experiments with ethylnitrosourea, 455

Assembly of ribosomes in Bscherichia coli, increased expression of ribosomal genes during inhibition, 23

Barteriophage Pl Cre-ZozP site-specific recombination. Effects of DNA supercoiling on catenation and knotting of recombi- nant products. %l 1

BAKER. T. S., HOSINSKY. G. E.. CASPAR, D. L. I).. GALL, C. & (:O~DENOIWH. I). A., Gap junction st,ructures. VII. Analysis of c’onnexon images obtained with rationic and anionic negative stains, 81

BANVII,LE, D. & WII,LIAMS, J. G., Developmental changes in the pattern of larval fi-globin gene expression in Xenopus laevis. Identification of two early larval P-globin mRNA sequences. 61 I

Base-pair kinetics and proton exchange of poly(rA) poly(rU) and poly(rI) (A’). 165

I~ECK, G. (see also ORANGE, T.). 347 J<EDWELL. D. M. (see also TAKEBE. Y,), 23 I%~~:FoRT. N. (see also GRANGE, T.), 347 BEI,LIS. M. (see also JUBIER-MA~RIN, V.), 547 I~ENNETT, P., STARR. R., EI.LIOTT, A. & OFFER, G., The

struct,ure of (‘-protein and X-protein molecules and a polymer of X-protein, 297

UERC., H. (‘. (see also KHAN, S.). 645 BERGDOI~L. M. (see also ROMBY, P.), 455 BERTRAND. K. P. (see also DANIELS, D. W.), 599 PI rabbit globin gene in nuclei and in supercoiled plasmids,

DNase I and nuclease S, sensitivity, 195 Biliprotein Y-phycocyanin from the thermophilic

cyanobacterium Mastigocladus laminosus. X-ray crystallographic structure and its resemblance to globin structures, 257

BLANQUET. S. (see also MAYAUX, J.-F.), 31 BLOW, D. M. (see also TSUKADA. H.), 703 BODE. W. (see also SCHIRMER, T.), 257

1300~. F P.. RUICROK, R. W. H. & VAN BR~QGEN, E. F. J.. Electron microscopy of influenza virus. A comparison of negatively stained and ice-embedded particles, 667

EONEN, I,. (see also LANG, 8. F.), 353 UOROWIEC, tJ. A. & GRALLA, J. D., Supercoiling response of the

lac ps promoter in vitro, 587 BOTSTEIN. D. (see also KUNES, S.), 375 Bovine mitochondria, primary structure and subunit

stoichiometry of F,-ATPase, 677 BRAYER, G. D. (see also FUJINACA, M.), 479 BROSETA. 1). (see also LEROY, J.-L.), 165 BI~ROESS. B. K. (see also CARTER. D. C.), 279 BUROF,SS. R. R. (see also ROE, J.-H.), 441 I~~;Tow. 1~. A. (see also AINLEY, W. M.). 565

(‘ANTOR. C’. R. (see also WOUENZIEN, P. L.). 67 “(‘a+” on the tip of Salmonella flagella, 735 CARTER. D. C’.. MELIS. K. A., O’DONNELL. S. E., BCRGESS.

IS. K.. FUREY. W. F., *JR, WANG, B.-V. & STOUT, C. D.. (‘ryst,al structure of Azotobackr cytochrome cg at 2.5 A resolution. 279

(‘ASPAR, 1). L. D. (see also BAKER, T. S.). 81 CASSI~Y, li. (see also YANG-YEN. H.-F.), 389 Cell division genes ftsQ. ftsA and ffsZ. structure and expression.

399 CHANDRASEKHAR. K. (see also AMMON. H. L.). 379 CHASSEROT. S. (see also GRANGE, T.), 347 Chemical potential measurements of deoxyhemoglobin S poly-

merization. Determination of the phase diagram of an assembling protein, 517

Chromatin of hsp 83 gene. Se~rosporn crassn and S, nuclease cleavage. 657

Chromosomal mapping of the mouse tyrtrsinr aminotransferase gene. 367

Chromosome. Eschrrichia coli K-12. sites of dnarl protein- binding in the replication origin, 529

cc-Chymotrypsin structure refined at 1.68 A reaolut,ion. 703 Circular DNA: triple rings. a new type of compact struct,urr, 251 Cleavage. :Ye:~rarosporct rm~,~o and R, nurleasr. in hsp 83 gene

chromatin. 657 Collagen fihrils. c@alline regions. 473 COLI.INS, R. A. & LAMBOWITZ. A. M.. RS.3. splicing in

.%wrospora mitochondria. Defective splicing of mitochondrial mRNA precursors in the nuclear mutant cyt16-1, 413

Connexon images obtained with cationic and anionic negative stains: gap junction structures. 81

co.rl gene of Saccha~omyces cerenisiae, the first two int.rons are closely related to an intron in the cytorhrome b gene of Schkosaccharomyces pombe, 353

C’-phycocranin from the ;llasiigocladus laminosus,

thermophilic ayanobaoterium X-ray crystallographic &u&Ire

and its resemblance to globin structures, 257 C-protein and X-prot,ein molecules and a polymer of X-prot,ein:

structure. 297 CRAIG. R. (see also CROWTHER, R. A.), 429 Cre-/ozP site-specific recombination, phage Pl. Efl’ect,s of DNA

supercoiling on catenation and knotting of rrcombinant products. 211

CROWTHER. R. A.. PADR~N, R. & CRAIQ. R.. Arrangement of t,he heads of mposin in relaxed thick filaments from tarantula muscle. 429

Crystal <tructure of rlzotobacfrr cyt,ochromr r5 at 2.5 ‘4 resolution. 279

Crystal structure. low resolution, of muconolactonr isomerase: a decamer with a s-fold symmetry axis, 311

Crystalline regions in collagen fibrils, 473 Crystallographic refinement of yeast aspartic acid tRNA. 119 Crystallographic study, preliminary, of an L-asparaginase from

Vibrio succinogenes, 179 CUMMINGB. c‘. (see also HULMES, D. J. S.). 473 Cyanobacterium Mastigocladus laminosw, X-ray

crystallographic structure of the biliprotein C-phycocyanin, and its resemblance to globin structures. 257

vii

Vlll INDEX

(‘~kchrome b gene of NchizosarcllurolrlycPs pontbe has an intron closelv related to the first two introns in the Sncchnromycrs cereoihw rorl gene. 353

(‘ytochrornc cs, dzofobacter. crystal structure at 2.5 x resolution, 279

(‘ytokrratins. basic (type II), of Xenopus lueviv epidermis, amino acid sequence microheterogeneities: evolutionary conservativity of helical and non-helical domains, 7 13

ryfZH-f nuclear mutant. defective splicing of mitochondrial mRSA precursors: RNA splicing in LVP I, msportr mitochondria. 413

DAIRI, T.. INOKUCHI. K., MIZUNO. T. & MIZUSHIMA, S., Positive control of transcription initiation in Es&&c& coli. A base substitution at the Pribnow box renders onzpF expression independent, of a positive regulator, I

DANIEI,S. D. W. & BERTRAND, K. P., Promoter mmations affecting divergent transcription in the TnlU tetracycline resistance determinant, 599

DELBAERE, L. T. J. (see also FUJINAGA, M.), 479 Deoxyhemoglobin S polymerization, chemical potential measure-

ments; determination of the phase diagram of an assembling protein, 519

DNA adducts, psoralen and acetylaminofluorene, repair by ARC exrinuclease, 725

DNA, circular: triple rings, a new type of compact structure, 251 DNA, complementary, complete, of rat tyrosine

aminotransferase mRNA. Deduction of the primary structure of the enzyme, 347

DNA discontinuous replication in Escher&ia coti is primed by approximately 10 to 12 residues of RNA starting with a purine, 45

DNA. lambda phage, pyrimidine dimers are not the principal pre-mutagenic lesions induced by ultraviolet light, 577

DNA opening and protein conformational change, assignment of the corresponding kinetic steps; temperature dependence of the rate constants of the Escherichia coli RNA polymerase- AP, promoter interaction, 441

DNA, plasmid, linearized, transformation of yeast, Formation of inverted dimers and recombinant plasmid products, 375

DNA supercoiling, effects on catenation and knotting of recombinant products; phage Pl Cre-ZozP site-specific recombination, 211

-DNA topoisomers, statistical mechanics. The helical worm-like chain, 319

DNA II, ribosomal, rat, characterization; identification of the highly repetitive DNA in the 3’ non-transcribed spacer, 389

dnaA protein-binding sites in the replication origin of the Escherichia CC& K-12 chromosome. 529

DNase 1 and nuclease S, sensitivity of the rabbit /f, globin gene in nuclei and in supercoiled plasmids. 195

Developmental changes in the pattern of larval p-globin gene expression in Xenopus laevis. Identification of two early larval fi-globin mRNA sequences, 611

Dielectric spherical cavity, electrostatic forces, 515 DIETRICH. ,J. U. (see also GRANGE, T.), 347 DOD, B. J. (see also JL~BIER-MAURIN, V.), 545 Drosophila melaaogastrr, UGA nonsense mutation in the alcohol

dehydrogenase gene, 221 DUMAS, P. (see also ROMB~, P.), 455 DRAMAS. P. (see also WESTHOF, E.). 119

EBEL, J. P. (see also ROMBY, P.), 455 Electron microscopy of influenza virus. Comparison of negatively

stained and ice-embedded particles, 667 Electron microscopy of rotary shadowed vinculin and vinculin

complexes, 543 Electrostatic forces in a spherical dielectric cavity, 515 Electrostatic interactions in proteins; calculation, 503 ELLIOTT, A. (see also UEIVNETT, P.), 297 Epidermis, Xenopus laevis, amino acid sequence

microheterogeneities of basic (type II) cytokeratins; evolutionary conservativity of helical and non-helical domains, 713

Eschwichia coli, evidence that discontinuous DNA replication is primed by approximately 10 to 12 residues of RNA starting with a purine. 45

Eschwirhiu coli g/tT. site-specific, mutagerir& virltl~ ~1 1, eak. glutamic acidinserting ochre suppressor. 343

Eschwiehia co/i. increased expression of ribosomal genes Iluring inhibition of ribosome assembly. 23

Escherichin ~02i K-12 chromosome. sit,es of dnrc.4 I)roteill-l)itltlil)g in the replication origin. 529

Escherichin co[i K-12, regulation of the phosphate rrgulon: regulation and role of the regulatory gene phoh’. 23 1

fi&:scher&hin co/i. nucleotidr sequence of the penes involved in phosphate t.ransport and regulation of’ the Iihosphate regulon, 2-1 I

&cherichia coli. positive control of transcription initiation: a base substitution at the Pribnow box renders vmpP expression independent of a posit.& regulator. 1

Escheriehin CO& RNA polymerase-1P, promoter interaction. temperature dependence of the rate constants. Assignment of the kinetic steps corresponding to protein ~~otlfi~rmaticlllal change and DNA opening. 441

Escherichia coli 16 S ribosomal RNA structure. Psoralen crosslinks and N-acetyl-N’-(p-glyoxylylbenzoyl)cystamine crosslinks detected by electron microscopy, 67

Escher%chin coli 16 S ribosomal RNA. three-tlimrr~sional arrangement, 53

Escherichin co[i or yeast tRSAA’p. studies of self-association. and of then interactions with E’scherkhia w/i tRSXV”‘; anticodon-anticodon interactions in solution, 107

Ethylnitrosourea, in a comparative study of the yeast pheiiylalanine system by phosphate alkplation experiments. 455

Evolution of t,hr Ll family in the genus Mus. 547 Evolutionary conservativity of helical and non-helical domains;

amino acid sequence microheterogeneities of basic (type II) cytokeratins of Xpnopu,s In&a epidermis, 713

Evolutionary implication of a new type of polymerase-lll- dependent terminator: end-to-end transcription of an A/rr family repeat, 7

Excinuclease. 813C. repair of psoralen and acetylarninofluorell(, DNA adducts. 725

EXPERT-BEZANCON, A. & WOLLENZIEN, P. L., Three-dimensional arrangement of the Escherichia coli 16 S ribosomal RNA, 53

EXPERT-REZAN~ON, A. (see also WOLLENZIEN, P. L.), 67

Fi-ATPase from bovine mitochondria. primary structure and subunit stoichiometry, 677

FAYAT, G. (see also MAYAUX, tJ.-F.), 31 FEARNLEY, I. M. (see also WALKER, J. E.), 677 Filaments, thick, relaxed, from tarantula muscle, arrangement of

the heads of myosin, 429 FINE, R. (see also GILSON, M. K.), 503 Flagella. Salmonelh, “cap” on the tip, 735 Flagellar rotation, constraints, 645 Folding pathway of fi-lactamase; effects of sulphate and urea on

the stability and reversible unfolding of a-lactamasr from Staphylococcus aureus, 331

FOX, M. S. (see also KUNES, S.), 375 FRANKE, W W. (see also HOFFMANN, W.), 713 FRANKLIN, K. A. (see also SANCAR, A.), 725 FRANZ, J. K. (see also HOFFMANN, W.), 713 FROMONT. M (see also GRANGE, T.), 347 ft.&?, f&l and ftsZ cell division genes. structure and expression,

399 FUJINAGA, M., DELBAERE, L. T. J., BRAYER, G. D. & JAMES,

M. N. G., Refined structure of a-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure, 479

FUREY, W. F., Jr (see also CARTER, D. C.), 279

GALL, C. (see also BAKER, T. S.), 81 Gap junction structures. Analysis of connexon images obtained

with cationie and anionic negative stains, 81 GAY, N. J. (see also WALKER, J. E.), 677 Gene, alcohol dehydrogenase, of Drosophila melanogaster, UGA

nonsense mutation, 221

INDEX ix

Gene. Bl globin, rabbit, in nuclei and in supercoiled plasmids. DNase I and nuciease S, sensitivity, 195

(Zrne expression, fi-globin, larval, in Xenopus taevis. developmental changes; identification of two early larval fi-globin mRNA sequences, 611

Gene hsp 83 chromatin, Neurospora cresaa and S, nuclease cleavage, 657

(:rne I!) lysozyme, phage P22, st,ructure inferred from homology with phage T4 lysozymr; implications for lysozyme evolution, 739

Gene phoR, regulation and role; regulation of the phosphate regulon of Eschrrichia coli K-12, 231

(iem. tyrosine aminotransferase, mouse: isolation. characterization and chromosomal mapping. 367

(Irene ~larl on the mitochondrial genome of ToruZopsis glabratn. 56.5

t:encs, ccl1 division, &Q. f&l and f&Z, structure and expression, 399

(+enrs involved in phosphate transport and regulation of the phospha.te regulon in Eschekhia cola’; nucleotide sequences, 241

(:enes and pseudogenrs for rat IJ3A and U3R small nuclear RNA, 183

Genes. ribosomal, increased expression during inhibition of ribosome assembly in Eschwichia coli, 23

(:enetic expression control of phenylalanyl-tRNA synthetase. Site-directed mutagenesis of the pheS. !I’ operon regulatory region in vitro, 31

Genome, mitochondrial, of the fission yeast Schizosacchoromyces pomhe. The cytochrome b gene has an intron closely related to the first two introns in the Saccharomyces cerevisiae ~0x1 gene, 353

GIBSON, B. W. (see also WALKER, J. E.), 677 &EC&, R. (see also ROMBY, P.), 107, 455 GILSON, M. K., RASHIN, A., FINE, R. & HONIG, U., On the

calculations of electrostatic interactions in proteins, 503

Ulobin pl gene, rabbit, in nuclei and in supercoiled plasmids, DNase I and nuclease S, sensitivity, 195

Globin structures, resemblance to structure of bihprotein C-phycocyanin from the cyanobacterium Mastigocludus laminosus, 257

P-Globin gene expression, larval, in Xenopus laevis, developmental changes; identification of two early larval fi-globin mRNA sequences, 611

gltT, Escherichia coli, site-specific mutagenesis yields a weak. glutamic acid-inserting ochre suppressor, 343

Glutamia acid-inserhing ochre suppressor is yielded by site- specific mutagenesis of Escherichia coli gltT, 343

GOODENOPGH, D. A. (see also RAKER, T. S.). 81 GRAILA. J. D. (see also UOROWIEC, J. A.), 587 GRANGE, T.. GU~NET, C.. DIETRICH, J. U., CHASSEROT, S.,

FROMONT, M., UEFORT, N., JAMI, J., HECK, G. & PICTET, R., Complete complementary DNA of rat tyrosine aminotransferasr messenger RNA. Deduct.ion of the primary structure of the enzyme, 347

CROSJEAN, W. (see also ROMBY, I?), 107 GRUNBERC-MANAGO, M. (see also MAYAUX, J.-F.), 31 G&NET, C. (see also GRANGE, T.), 347 GU~RON, M. (see also LEROY, J.-L.), 165 GITRSKY, G. V. (see also VENGEROV, Y. Y.), 251

HAGE, A. (see also YAMAGUCHI, M.), 644 HAN, S., UDVARDY, A. & SCHEDL, P., Neurosp0ra craasa and S,

nuclease cleavage in hsp 83 gene chromatin, 657 HARDISON, R. C. (see MARGOT, J. R.), 195 HAYES, D. H. (see also WOLLENZIEN, P. L.), 67 Head arrangement of myosin in relaxed thick filaments from

tarantula muscle. 429 HEIJNE, G. VON, Signal sequences. The limits of variation, 99 Helical worm-like chain: statistical mechanics of DNA

topoisomers, 319 Hemoglobin, lamprey, from Petromyzor ma&us, refinement of a

molecular model, 147 HENRICKSON. W. A. (see also HONZATKO, R. U.), 147 HERRMANN, B. (see also MOLLER, G.), 367

HESS. ,J., PEREZ-STABLE, C., WC, G. J., WEIR, U.. Tr~oco. I., Jr. & SH z~, (‘.-K. J End-to-end transcription of an A/u family repeat. A new type of polymerase-III-dependent terminator and it,s evolutionary implication. 7

Highly repetitive DNA identification in the 3 non-transcribed spacer: rat. ribosomal DNA II, 389

HIKAI. Y. (see also YAMAGITCHI, M), 644 HIROTA. Y. (see also MATSUI, M.). 529 Hosss. R (see also ABREMSKI, K.). %I 1 HOFFMANX. W’., FRANZ, J. K. & FRANKE. W. W.. Amino acid

sequence microheterogeneities of basic (type II) cyto- krratins of Xenopun laevis epidermis and evolutionary conservativity of helical and non-helical domains. 713

HOLLIES. D. F. (see also HULMES, D. J. S.). 4i3 HONIG. U. (see also GILSON, M. K.). 503 HONZATKO. K. H.. HENDRICKSON. W. A. & LOVE. W, E..

Refinement of a molecular model for lamprev hemoglobin from Petromyzon marinns. 147

HOI.SSIER, C. (see also ROMBY, P). 107 hsp 83 gene rhromatin. Xearusporn fmssff and S, nuclense

cleavage. 6.57 HUBEH. R. (see also SCHIRMER, T.). 257 HULMES, D. J. S., HOLMES, D. F. & CUMMINCX. (’ (‘rystalline

regions in collagen fibrils, 473 Hydrogen bonding and solvent structure. analysis; refined

structure of a-lytic protease at I.7 A resolut,ion. 479

Ice-embedding and negative staining compared in electron microscopy of influenza virus, 667

IKEDA. T , ASAKURA, S. & KAMIYA, R., “Cap” on the tip of lSalmon&a flagella, 735

Influenza virus, electron microscopy; comparison of negatively stained and ice-embedded particles, 667

INOKUCHI. K. (see also DAIRI, T.), I Inverted dimer and recombinant, plasmid products formation in

transformation of yeast with linearized plasmid DNA. 375 IZUMIMOTO. M. (see also YAMAGTJCHI, M.). 621

JAMES. M. N G. (see also FUJIAAGA. M.). 479 JAMI, J. (see also GRANGE, T.), 347 JUBIER-MA~RIN. V., DOD, B. J., BELLE., M.. PIECHACZYK. M. &

R~IZES, G., Comparative study of the Ll family in the genus M~Ls. Possible role of retroposition and conversion events in its concerted evolution. 547

KAMISOYAMA. H. (see also YAMAGIJCHI, M.), 644 KAMIYA. ft. (see also IKEDA, T.). 735 KATZ. U. A.. GLLIS, D. & WYCKOFF, H. W’.. Low resolution

crystal structure of muconolactone isomerase. A decamer with a 5-fold symmetry axis, 311

KHAN, S., MEISTER, M. & BERG. H. C., Const,raints on flagellar rotation, 645

KHORLIN, A. A. (see also VENGEROV, Y. Y.), 251 Kinetic steps corresponding to protein conformatianal change

and DNA opening; temperature dependence of the rate c-onstants of the Escherichia coli RNA polymerase-iP,, promoter interaction. 441

KITANI. T , YODA, K., GGAWA, T. & OKAZAKI, T., Evidence that discontinuous DNA replication in Escherichia coli is primed by approximately IO to 12 residues of RlYA starting with a purine, 45

KNIGHT, P. (see also WALKER, M.), 635 Knotting of recombinant products, effects of DNA supercoiling;

phage Pl Cre-loxP site-specific recombinat,ion. 211 KOBAYASHI. -1. (see also AMEMURA, M.), 241 KUNES. S.. BOTSTEIN, D. & Fox, M. S., Transformation of yeast

with linearized plasmid DNA. Formation of inverted dimers and recombinant plasmid products. 375

Ll family in the genus Mus, a comparative study; possible role of retroposition and conversion events in its concerted evolution, 547

Zac p’ promoter, supercoiling response in vitro, 587 /i-Lactamase from Staphylocoeeus aureua, effects of sulphate and

urea on the stability and reversible unfolding; implications for the folding pathway of b-lactamase, 331

x INDEX

LAMBOWITZ, A. M. (see also COLLINS, R. A.), 413 I (see also Phage), 577 ,U’s-RNA polymerase interaction, temperature dependence of

the rate constants; assignment of kinetic steps corresponding b pro&e& conformational change and DNA opening, 441

Lamprey hemoglobin from Pelromyzon ma&us. refinement, of a molecular model. 147

LANG. S. F., AHNE, F. & BONEN, L., The mitochondrial genome of the fission yeast Schizosaccharomyces pombe. The cytochrome b gene has an intron closefy, related to the first two introns in the Saccharomyces cerev~wae ~0x1 gene, 353

Larval p-globin gene expression in Xenopux [awin, developmental changes. Identification of two early larval B-globin mRNA sequences, 611

LEHRACH, H. (see also MRLLER, G.), 367 LEROY, J-L.. UROSETA, D. & G&RON, M., Proton exchange and

base-pair kinetics of poly(rA) ’ poly(rI’) and poly(rI) poly(rC), 165

LOVE, W. E. (see also HONZATKO, R. U.), 147 LUTKENHAUS, J. (see also YI, Q.-M.). 399 T,vsozyme evolut,ion; structure of phage P22 gene 29 lysozyme

inferred from homology with phage T4 lysozyme, 739 Lysozyme, gene 19. phage P22, structure inferred from

homology with phage T4 Ipsozyme: implications for Ivsozyme evolution, 739

or-L&c protease, refined structure at 1.7 A resolution: analysis of hydrogen bonding and solvent structure. 479

MACREADIE, I. G. (see also AINLEY. W. M.). 565 MAKAROV, V. L. (see also VENCEROV, Y. T.), 251 MAKINO. K., SHINAGAWA. H. & NAKATA, A.. Regulation of the

phosphate regulon of Escheriehia coli K-12: regulation and role of the regulatory gene phoR, 23 I

MAKINO. K. (See also AMEMt!RA, M.). 241 MAKOOT. .J. 13. 6 HARDISON, K. (1.. DNasc 1 a.nd nuclrxse S,

sensitivity of the rabbit 81 globin gene in nuclei and in supercoiled plasmids, 195

MARTIN. P. F.. PLACE. A. R.. PENTZ. E. & SOFER. 12’.. I’(:i\ nonsense mutation in the alcohol dehydrogenase genr of I)rosophila melanogaster, 221

N&igocladws IamirroslLs, ;Y-ray crystallographic structure of’ the biliprotein C‘-phycocyanin and its resrmblanc~r to globin structures, 257

MATSUI. M., OKA. A., TAKANAMI, M., YAS~~I,A, S. & HIROTA. Y.. Sites of dtmA prokin-binding in the replication origirl of thr Escharichia coli K-12 chromosome, 529

MATTHEWS, I<. W. (see also WEAVER. I,. H.). 739 MAYAII?I, J-F., FAYAT. G., PAN~ERT. M.. SPRINGER. RI..

GWNBERG-MANACO, M. & ULANQI’ET, S.. (‘ontrol of phenylatanyl-t RNA synthetase genetic expression. Site- directed nutagenesis of thr pheS. 7’ operou regulatory region itc L’ih. 3 1

MEISTER. M. (see also KHAN, S.). 645 MEWS, K. A. (see also CARTER. U. C’.), 279 mRNA precursors, mitochondrial, defective splicing in the

nuclear mutant cytlX-I: RNA splicing in ,Vr?tros~/,c~-rr mitochondria, 413

Messenger RNA. rat tyrosine aminotransferase. complete c*omplernentary DNA; deduction of the primary structure of the enzyme, 347

mRNA sequences. P-globin. larval, rarly. identification: developmental changes in the pattern of larval fi-globin gene expression in Xenrvpus laez%s. 611

Microheterogeneities. amino acid sequence. of basic (type II) cytokeratins of Xerwpvs laeois epidermis and evolutionar> conservativitg of helical and non-helical domains, 713

MILAM. I,. M., Electron microscopy of rotary shadowed vinculin and vinculin complexes, 543

MITCHINSON, (‘. & PAIN, R. H., Ell’ects of sulphate and urea on the stability and reversible unfolding of B-lactamase from StaphyZoroccus (LUTYUS. Implications for the folding pathwa) of p-lactamase, 331

Mitochondria, bovine, primary structure and subunit stoichiometry of F,-ATPase, 677

Mitochondria, ~V~urospom, RNA splicing; defective splicing of

mitochondriat mRXA precursors in the nuclear mutant cytl8-1, 413

Mitochondrial genome of the fission yeast Srhizosaccha,onlyce.s pornbe. The cytochrome h gene has an intron closely related to the first two introns in the Saceharomyce~ crr~&ca~+o.rI genr. 353

Mitochondria.1 genome of Torulop~sis glabrata, wwl gene. ,565 MIURA. &I. (see also TAKEBE. Y.), 23 MIZUNO. T. (see also DAIRI. T.), 1 MIZUSHIMA, S. (see also DAIRI, T.), I Molecular model refinement for lamprey hemoglobin from

Petromyzon marinus. 147 MORAS, D. (see also ROMBY, P.), 455 MORAS. D. (see also WESTHOF. E.), 119 Mouse tyrosinr aminotransferase gene, isolation.

characterization and cshromosomal mapping. 367 Muconolaet,one isomerase, low resolution cry&al structure: ii

deramer with a 5-fold symmetry axis, 311 M~~LI,EEL C:.. SCHERER. (‘:.. ZE<T~RAF. H., RIIPPICK’I.. S..

HERRMAN&.. 8.. LEHRACH. H. $ SCHULTZ. t;.. Ixolatkm characterization and chromosomal mapping of t,hr mouse tyroaine aminotransferasr gene, 367

MURPHY. K (‘. (see also AMMON. H. I,.). li9 MIJRPHY. R. F. (see also ~YOI.LENZIEN. P. I,.). 67 Mus genus, comparative stud>- of the Ll family; possible rolr of’

retroposition and conversion events in its concert~etl evolution. 547

Muscle. tarantula. arrangement of t,hp heads of myosirt in rela~rcl thick tilaments, 429

Muscle. vertebrate. Z-lineb. fine structure. Model and comlrutrl~ simutat,ion of Z-line architecture. 621

Mutagenrsis: pyrimidinr dimers are not the principal l,l’(‘~ mutagenic, lesions inducrd in lambda phage 1)N.A t)J ultraviolet, light. 577

Mut,agenesis. &e-directed. of the &S, 7’ operon reyulatoq. region in ~ifro: control of phenglalan~l-t RNA synthektse genetic expression, 31

Mutagenesis. site-specific. of &schr,ichia co/i gltT yields a weak. @utanli(~ wid-inserting ochrr suppressor. 343

Mutant, nuclrar. cytlK-1, defective splicing of tnitochondrial mKNA precursors: RSA splicing iti .Tr I, ,ospwa mitorhondria, 413

IvIutations. pronwter, aflecting divergent transcription in thr TnZ/l trtrxchycline resist,ance determinant, 599

Myosin rnolrc~lrs. negative staining. 535

:V-acet>-I-S’-(p,-glyoxylylbenzoyl)cystamine crosslinks detected by etect,ron microscopy. Structure of the Escherichia coli 16 S ribosomal RNA, 67

~AKATA, A. (see also AMEMURA, M.), 241 NAKATA, A. (see also MAKINO. K.), 231 Negative staining of myosin molecules, 535 ~VeVeuros;l/~~rcr rra8sa and S, nurlease cleavage in hsp 83 gene

chromatin, 657 .Veuronporn mitochondrial RNA splicing. Defective splicing of

mittrchondrial mRNA precursors in the nuclear mut.ant cyflX-I. 413

NOMURA. M. (see also TAKEBE, Y.), 23 Nonsense mutation UGA in the alcohol dehydrogenase gene of

Drosophila melaqaster, 221 NORTHROP. F. I). (see also WALKER, J. E.), 677 Nuclease S1 sensitivity of the rabbit 81 globin gene in nuclei and

in supercoiled plasmids, 195 Nuclei, DBase I and nuclease S, sensitivity of the rabbit 81

globin gene, 195 Nucleotide sequence of the genes involved in phosphate

transport and regulation of the phosphate regulon in Eschrrichia co&, 241

Ochre suppressor, weak, glutamic acid-inserting, is yielded by site-specific mutagenesis of Escherichia coli g&T. 343

O’DONNELL, 8. E. (see also CARTER, D. C.). 279 OFFER. G. (see also BENNETT, P.), 297 OCAWA. T. (see also KITANI, T.), 45 OKA. A. (see a,tso MATSUI. M.), 529

INDEX xi

OKAZAKI, T. (see also KITANI, T.), 45 OLLIS, D. (see also KATZ, IS. A.), 311 ompF expression is rendered independent of a positive regulator

by B base substitution a&. the Pribnow box; positive control of transcription initiation in Escherichiu co& 1

Pl (see also Bacteriophage), 211 P22 (see also Phage), 739 PADR~N, R. (see also CROWTHER, R. A.), 429 PAIN. R. H. (see also MITCHINSON, C!.), 331 PANVERT, M. (see also MAYAUX, J-F.), 31 PARSECIAN. V. A. (see also PRO~TY, M. S.), 517 PENTZ, E. (see also MARTIN, P. F,), 221 PEREZ-STABLE, C. (see also HESS, J.), 7 Petromyzon marinu8. refinement of a molecular model for

lamprey hemoglobin, 147 Phage lambda DNA, pyrimidine dimers are not the principal

pre-mutagenic lesions induced by ultraviolet light. 577 l’hage P22 gene 19 Ipsozyme, structure inferred from homology

with phage T4 iysozymr: implications for iysozyme evolution, 739

Phase diagram of an assembling protein; chemical potential measurements of deoxyhemogiobin S polymerization, 517

Phenyialanine system, yeast, a comparative study by phosphate alkylation experiments with ethyinitrosourea, 455

Phenylalanyi-tRNA synthetase genetic expression control. Site- directed mutagenesis of the pheS, 7’ operon regulatory region in vitro. 31

$PS. 2’ oprron regulatory region, site-directed mutagenesis in vitro: control of phenyialanyi-tRNA synthetase genetic expression. 31

phoR gene, regulation and role; regulation of the phosphate regulon of Escherichia eoli K-12, 231

Phosphatr alkylation experiments with ethyinitrosourea, a comparative study of the yeast phenylaianine system. 455

Phosphate reguion of Escherichia coli K-12, regulation and role of the regulatory gene phoR. 231

Phosphate transport and regulation of the phosphate regulon in Rs&arichia eoli. nucleotide sequence of the genes involved. 241

I'I("I'ET. It. (see also (;RANCE, T.), 347 PIWHACZYI(. M. (see also JUBIER-MAURIN, V.). 547 PLACE, A. K. (see also MARTIN, I’. F.), 221 t’lasmid DNA, linearized, transformation of yeast. Formation of

inverted dimers and recombinant piasmid products, 375 Plasmids, supercoiled, DNase I and nuclease S, sensitivity of the

rabbit j, giobin gene. 195 Poiymerase-111.dependent terminator, new, and its evolutionary

implication: pm-to-rnd t.ranscription of an Alz~ farnil! repeat, 7

l’otymerizat,ion of deoxyhemoglobin S, chemical potential measurements; determination of the phase diagram of an assembling protein, 517

Poly(rA) . poiy(rU) and poly(rI) poly(rC):), proton exchange and base-pair kinetics, I65

Positive control of t,ranscription initiation in Escherichia coli. A base substitution at the Pribnow box renders ompF expression independent of a positive regulator. 1

POTEETE, A. R. (see also WEAVER, L. H.), 739 POWELL. S. .J. (see also WALKER. .J. E.), 677 Pribnow box, a base substitution renders ompF expression

independent of a positive regulator; positive control of transcription initiat.ion in Escherid& coti, 1

Primer RNA of Escherichia coli I)NA synthesis, 45 Promoter mutations affecting divergent transcription in th?

TnlO tetracycline resistance determinant, 599 Protein conformational change and DNA opening, assignment of

the corresponding kinetic steps; temperature dependence of the rate constants of the Escheriehiu coli RNA polymerase- lPR promoter interaction, 441

Protein-binding, dnaA, sites in the replication origin of the Escherichia coli K-12 chromosome, 529

Proteins, the calculation of electrostatic interactions, 503 Proton exchange and base-pair kinetics of poly(rA) poiy(rl’)

and poiy(r1). poly(rC), 165 PROUTY.M. S., SCHECHTER. A. S. & PARSECIAN, V. A.,Chemical

potential measurements of deoxyhemogiobin S

poiymerization. Determination of the phase diagram of an assembling protein, 517

Pseudogenes and genes for rat U3A and 113B small nuclear RNA, 183

Psoralen and acetyiaminofluorene DNA adducts. repair by ABC excinuclease, 725

Psoralen crosslinks detected by electron microscopy. Structure of the Escherichia co/i 16 S ribosomai RNA. 67

Pyrimidine dimers are not the principal pre-mutagenic* lesions induced in lambda phage DNA by ultraviolet light, 577

Rabbit /?I giobin gene in nuclei and in supercoiled plasmids. DNase I and nuclease S, sensitivity, 195

RAFTERY, I,. A. & YARUS, M., Site-specific mutagenesis of Escherichia coli glt7’ yields a weak. glutamic acid-inserting ochre suppressor. 343

RASHIN. A. (see also GILSON. MI. K.), 503 Rat ribosomai D?JA II characterization. Identification of the

high]? repetitive DNA in the 3’ non-transcribed sparer. 389 Rat tgrosme aminotransferase mRNA, complete complementary

DNA; deduction of primary structure of the enzyme. 347 Rat 1’3A and U3U small nuclear RNA. genes and pseudogenes.

183 Recombinant plasmid and inverted dimer formation in

transformation of yeast with linearized plasmid DNA, 375 Recombination. site-specific. Cre-loxP, phage Pl. Effects of DNA

supercoiling on catenation and knotting of recombinant produrts. 211

RECORD. M. T.. -Jr (see also ROE, J.-H.), 441 Refinement of a molecular model for lamprey hemoglobin from

PPtromyton marinu8. 147 Regulation of the phosphate reguion in Eschrrichin coli.

nuric~ot,ide seyuencc of the genes involved. 241 Regulation of the phosphate regulon of Enchrrichin to/r K-12:

regulation and role of the regulatory gene phoK. 231 RENXELL. II. (see also WEAVER, L. H.). 739 Repair of psoraien and acetylaminofluorene DNA adducts by

AW excinuciease, 725 Replication. DNA. discontinuous. in E.seh,erichia co/i is primed

by approximately If) to I:! residues of RX,% starting w&h a purine. 4.5

Replication origin of t,he Escherichia coli K-12 c*hromosome, sites of dnaA protein-binding, 529

RSA. nuc1ea.r. small. genes and pseudogenes for rat T:lA and r3u. 183

RNA polymerase-Us interaction, temperature dependence of the rate constants: assignment of kinetic steps vorresponding to protein conformational change and DNA opening. 141

RNA. primer. of Escherichia coli DNA synthesis, 45 RNA, 16 S ribosomal. Escherichin co/i, structure. Psoralen

prosslinks and ~~:-acetyl-,~-(p-giyoxylylbenzo~l)~yst~amin~ (<rosslinks det,ected by electron microscopy, ti7

RNA. 16 S ribosomal. Escherichia co/i. t,hrrr-ciimrnsic,nal arrangement. 53

RNA splicing in Xeurospora mitochondria. Defective splicing of mitovhondriai mRNA precursors in thr nuclear mutant cytlb-i. 413

Ribosomal DNA II. rat. characterization: identification of t,he highly repetitive DNA in the 3’ non-transcribed sparer, 389

Ribosomal genes. increased expression during inhibition of ribosome assembly in Escherich.in coli, 23

Ribosomal 16 S RNA, Escherichi~ coii. strwturr. Psoralen (<rosslinks and N-acetyl-N’-(p-glyoxyiytbenzopl)cyst.aminr crosslinks det,ected by electron microscopy. 67

Ribosomal I6 S RNA. Escherich~ia coli, three-dimensional arrangement. 53

ROBRON, R. 112. (see also YAMAGUCHI, M.), fill ROCKENBACH, S. (see also YI. Q.-M.), 399 ROE. J.-H., ULXGESS. R. R. & RECORD, M. T.. Jr, Temperature

dependence of the rate constants of the Bschwichia coli RNA poiymerase-IP, promoter interaction. Assignment of the kinetic steps corresponding to protein conformationat <,hange and DNA opening, 441

ROIZES. C:. (see also JUBIER-MAURIN, V.), 547 ROMB~. P.. GIEG~. R.. HOUSSIER, (‘. & GROWEAN. H.,

.1nticodon-anticodon interactions in solution. Studies of the

xii INDEX

self-association of yeast or Escherichia coli tRNAAsp and of their interactions with Escherichia coli tRNAVs’, 167

R~MHY. P., >fortns, D.. ~SRCDOLI.. M.. lkkf~s. I'.. Vr~ssctv, V. V.. WESTHOF. E.. EREI,. *I. P. & (:IEGR. R.. Yeast tRNAArp tertiary structure in solution and areas of intrra&on of the tRNA with aspartyl-tRNA synthrtase. A comparative study of the yeast phenylalaninr system by phosphate alkylation experiments with ethylnitrosourea. 455

Rotary shadowed vinculin and vinculin c~omplexes, electron mlcrosc”yy , 543

~OTI~HI.l~M. 1, I. (SW also J’AN(:-\‘EN. H.-P.). 3%) KUIOHOK, K. Lv. H. (see also h)Y. I<‘. I’.). 667 K~~N~~I~~K. M. ,J. (see also WALKER. .I. I%). (ii7 KIIP~~~RT. S. (see aiso Wi?LLEK. (i.). :%7

Aacchar~myces cww~slae co:rl gene. the first two introns alp closely related to an intron in the cyttrchrome h gene of SchizosuccharomycPs pornhe. 353

Salmonella flagella. “cap” on the tip, 735 SANCAR, A., FRANKLIN, K. A., SANCAR, G. & TANG, M.-s., Repair

of psoralen and acetylaminofluorene DNA adducts by ABC excinurlease. 7%

SAN~AR, G. (see also H.4iic.4R. A.). 725 SARASTE, M. (see also WALKER. *J. K.), 677 SCHECHTER. A. N. (see also PXOITTY. M. S.). 517 SCHEDL, I’. (see also HAN, S.), 657 SCHEKER, G. (see also WULLER, G.). 367 SCHIRMER. T., L%oDE:. W. & HUBER, It., X-ray crystallographic

structure of the light-harvesting biliprotein (I-phycocyanin from the thermophilic cyanobacterium .lilaxtigoclndrrs krminoszrs and its resemblance to globin struct.ures. 255

Schitosaccharomyces pombe mitochondrial genome. The cytochrome b gene has an intron closely related to the first two introns in the Saccharomyces ceret,isiar co.rl gene. 353

&XtiTZ. G. (see also MiiLLRR, C:.). 367 SEMENOV, T. E. (see also VENGEROV, Y. Y.). 251 Sequence. amino acid. microheterogeneities of basic (type 11)

cytokeratins of Xenopus laevis epidermis and evulutionary cnonservativity of helical and non-helical domains. 7 13

Sequence, nucleotide, of the genes involved in phosphate transport, and regulation of the phosphate regulon in Esrherichia coli, 241

Sequences. mRNA. P-globin. iarvai. early. identificat,ion: developmental changes in the pattern of larval P-globin gene expression in Yenopus la&s, 611

Sequences, signal; the limits of variation, 99 SHEA. (‘.-I<. .J. (see also HESS, J.). 7 SHIMADA. .J. & YAMAKAWA, H., Statistical mechanics of DNA

topoisomers. The helical worm-like chain, 319 SHINACAWA, H. (see also AMEMURA, M.), 241 SHINAGAWA, H. (see also MAKINO, K.). 231 Signal sequences. The limits of variation, 99 Small square (SS) net structure of the narrow Z-line. 644 SOFER, iv. (see also MARTIN. P. F.). 221 SOSINSKY. 0. E. (see also BAKER, T. S.), 81 Spacer, non-transcribed. 3’, identification of the highly repetitive

DNA; rat ribosomal DNA 11, 389 Splicing, defective. of mitochortdrial mRNA precursors in the

nuclear mutant cytlX-1: RNA splicing in ,V~ctrosporu mitorhondria. 413

SPRINGRR, M. (see also MA~AVX, J-F.). 31 Stained connexons, image analysis: gap junction structures, 81 St,aining. negative. compared with ice-embedding in electron

microscopv of influenza virus, 667 Staining, negative, of myosin molecules, 535 Staphyloceoeus (ZWTCU~S, effects of sulphate and urea on the

stability and reversible unfolding of fi-lactamase: implications for the folding pathway of p-lactamase. 331

STARR, R. (see also BENNETT, P.). 297 Statistical mechanics of DNA topoisomers. The helical worm-like

chain, 319 STOVT. (1. D. (see also CARTER, D. C.), 279 STRELTSOV. 8. A. (see also VENGEROV. Y. Y.), 251 STROKE, I. L. Et. WEINER, A. M., Genes and pseudogenes for rat

Lr3A and LT31J small nuclear R,NA, 183

STRONIER. Pi. H. (see also YAMAOI.(‘EII. M.). 6:!I Structure of a-chymotrypsin refined at I .6X .9 rrsolul ioii 703 Structure. compact, of circular 1)N.A: tripIt> rings. %I Structure of (‘-protein and S-protein molecules and ii polvtner of’

S~protein, “97

Struct,ure. cr~vstal. low resolution. of tnuc~o~~olact~~~l~ isomerahe: ii dreamer with a &fold symmetry axis. 31 1

Strurturc of t.hr F:.ucherichin co/i I6 S ribosomal RS;\. 3X Struc*ture of the Rschurirhicz CO/L I6 S ribosomnl RN.-1 I’sot-alrn

crosslinks and S-arrtyl-S’-(~-pl~ox~i~lt~e~~~o~l)~~~~ta~~~i~~~~ crosslinks drt,ected hy electron microscopy, 67

Structure. tine. of wide and narrow vertebrate muscle Z-lines. A proposed model and computer simulation of Z-line architecture. 621

Structure and expression of the cell division genes ,[/,sQ. ,ft,~,l and fl.sZ. 399

Wurtrrre of phagr P22 gene I!1 Iysozyme inferred frlnrl its homology with phage T4 Iysozymr. Tntplication* for Iysozyme evolution, 739

Structure, primary, of enzyme, deduced from complete complementary DNA of rat tyrosinr amirtotransferasr mRNA. 347

Structure. primary, and subunit st,oichiometry of P,-.ATPasr from hovinr mitochondria, 677

Structure, refined, of a-lytie protease at I.5 .% resolution. Analysih of hydrogen bonding and solvent structure. 179

Structure. small square net, of the narrow Z-line, 644 SWucture. tertiary, of yeast tRNAASp in solution, and areas of

interaction of the tRNA with aspartyl-tRNA synthetase. Comparative study of yeast phenplalanine system by phosphat.e alkylation experimenm with ethylnitrosourea. 455

Structure, X-ray crystallographic, of the light-harvesting biliprotein Cphycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures, 2%

Structures, gap junction; analysis of connexon images obtained with cationic and anionic negative stains, 81

SUBRAHMANYAM, C. S. (see also YANG-YEN, H.-F.), 389 Sulphate and urea, effects on the stability and reversible

unfolding of /J-lactamase from Staphylococcus aureus. Implications for the folding pathway of p-lsctamase, 331

Supercoiling, DNA, effects on catenation and knotting of recombinant products; phage PI Cr&oxP site-specific recombination, 211

Supercoiling response of the lac p’ promoter in z&o, 587

T4 (see also Phage), 739 TAKANAMI, M. (see also MATSUI, M.), 529 TAKEBE. Y., MIURA. A., BEDWELL, D. M., TAM, M. $ NOMURA,

M., Increased expression of ribosomal genes during inhibition of ribosome assembly in Escherichia coli. 23

TAM, M. (see also TAKEBE, Y.), 23 TANG, M.-s. (see also SANCAR, A.), 725 Tarantula muscle, arrangement of the heads of myosin in relaxed

thick filaments, 429 Temperature dependence of the rate constants of the Escherichia

coli RNA polymerase-Us promoter interaction. Kinetic steps corresponding to protein conformational change and DNA opening, 441

Tetracycline resistance determinant, T&O. promoter mutations affecting divergent transcription, 599

TINOCO, I., Jr (see also HESS, J.), 7 TnlO tetracycline resistance determinant, promoter mutations

affecting divergent transcription, 599 Topoisomers, DNA, statistical mechanics; the helical worm-like

chain, 319 Tondopsis glabrata, var1 gene on the mitochondrial genome, 565 Transcription. divergent, in the TnlO tetracycline resistance

determinant, and promoter mutations, 599 Transcription, end-to-end, of an Alu family repeat. A new type

of polymerase-III-dependent terminator and its evolutionary implication, 7

Transcription initiation in Escherichia coli, positive control; a

INDEX Xl11

base substit.ution at the Pribnow box renders on@’ expression independent of a positive regulator, 1

Transfer RNA, aspartic acid, yeast, crystallographic refinement. 119

tRNAAsP, yeast or Escherichia co&, studies of self-association. and of their interactions with Escherichia co/i tRNA”“‘: anticodon-anticodon interactions in solution, 107

tRNAASP, yeast, tertiary structure in solution, and areas of interaction of the tRNA with aspartyl-tRNA synthetase. Comparative study of yeast phenylalanine system by phosphate alkylation experiments with ethylnitrosourea, 455

tRNA”“, Excherichia, coli, interactions with yeast or Eschrrichia coli tRNAAsp, 107

Transformation of yeast with linearized plasmid DNA. Formation of inverted dimers and recombinant plasmid products, 375

TRIWICK, J. (see also WALKER, M.), 535 Triple rings: a new t,ppe of compact structure of circular DNA.

251 TSUKADA. H. & UI,OW, D. M.. Structure of a-chymotrypsin

refined at I.68 A resolution, 703 TYBULEWICZ, V. L. J. (see also WALKER, J. E.), 677 Tyrosine aminotransferase gene, mouse; isolation,

characterization and chromosomal mapping, 367 Tyrosine aminotransferase mRNA, rat, complete complementary

DNA; deduction of primary structure of the enzyme, 347

1J3A and 113U small nuclear RNA, rat,, genes and pseudogenes. 183

UDVARDY, A. (see also HAN, S.), 657 I!GA nonsense mutation in the alcohol dehydrogenase gene of

Drosophila melanogaster, 221 LJltraviolet light and mutagenesis: pyrimidine dimers are not the

principal pre-mutagenic lesions induced in lambda phage DNA, 577

lrrea and sulphate, effects on the stability and reversible unfolding of /?-lactamase from Staphylococcus aureus. Implications for the folding pathway of /I-lactamase, 331

VAN URZICGEN, E. F. J. (see also BOOY, F. P.), 667 varl gene on the mitochondrial genome of Tomlopsis glubrata,

565 Variation limits: signal sequences, 99 VENGEROV, Y. Y., SEMENOV, T. E., STRELTSOV, S. A., MAKAROV,

V. L., KHORLIN, A. A. & GUBSKY, G. V., Triple rings: a new type of compact structure of circular DNA, 251

Vertebrate muscle Z-line fine structure. Proposed model and computer simulation of Z-line architecture, 621

Vibrio succinagenes, preliminary crystallographic study of an L-asparaginase, 179

Vinculin and vinculin complexes. rotary shadowing and electron microscopy. 543

Virus, influenza, electron microscopy; comparison of negatively stained and ice-embedded particles, 667

VLASSOV, V. V. (see also ROMBY. P.), 455

WALKER, J. E., FEARNLEY, I. M., GAY, N. J., GIBSON, 13. W.. NORTHROP, F. D., POWELL, S. J., RUNSWICK, M. J., SARASTE. M. & TYBULEWICZ, V. L. J., Primary structure and subunit stoichiometry of F,-ATPase from bovine mitochondria. 677

WALKER, M.. KNIGHT. P. & TRINICK. J., Negative staining of myosin molecules, 535

WANG, B.-C. (see also CARTER, D. C.), 279 WARD, J. E., Jr (see also YI, Q.-M.), 399 WEAVER. L. H., RENNELL. D., POTEETE, A. R. & MATTHEWS,

IS. U’.. Structure of phage P22 gene 19 lysozyme inferred

from its homology with phage T4 Iysozyme. Implications for lysozyme evolution, 739

WEINER, A. M. (see also STROKE, I. L.). 183 WEIR. B. (see also HESS, J.), 7 WESTHOF, E.. D~TMAS, P. & MORAS, D.. (:rystallographic

refinement of yeast aspartic acid transfer RNA, I19 WESTHOF, E. (see also ROMBY, P.). 455 WILLIAMS, J. G. (see also UANVILLE. D.). 611 WLODAWER, A. (see also AI\IMON, H. L.). 179 WOLLENZIEN. P. L.. MURPHY, R. F., CANTOR. (‘. It.. EXPERT-

BEZANCON, A. & HAYES, D. H.. Structure of the Esebrichia coli 16 S ribosomal RNA. Psoralen crosslinks and ,Y-acetyl- S’-(p-glyoxylylbenzoyl)cystamine crosslinks detected hy electron microscopy, 67

WOLLENZIEN, P. L. (see also EXPERT-BEZANCON, A.), 53 WOOD. R. D.. Pyrimidine dimers are not the principal pre-

mutagenic lesions induced in lambda phage DNA hy ultraviolet light, 577

WV, G. J. (see also HESS, J.). 7 WYCKOFF, H. W. (se? also KATZ, U. A.). 311

Xenopus Levis, developmental changes in t.he pattern of larval B-globin gene expression: identification of two early j&globin mRNA sequences. 611

Xenopus laeais epidermis, amino acid sequence microhetero- peneities of basic (type II) cytokeratins: evolutionary conservativity of helical and non-helical domains, 713

X-protein and C-protein molecules and a polymer of X-protein; structure, 297

X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from t,he thermophilic cyanobacterium Mastigocladus laminosvs and its resemblance to globin structures, 257

YAMAOUCHI, M., IZUMIMOTO, M., ROBSON, R. M. h STROMER. M. H., Fine structure of wide and narrow vertebrate muscle Z-lines. A proposed model and computer simulat,ion of Z-line architecture, 621

YAMAOUCHI, M., HIRAI, Y., HAGE, A., KAMISOYAMA, H. & ANDERSON, W. D., Small square (SS) net structure of the narrow Z-line (Appetiiz to YAMAGUCHI, M. ef a,l., 621), 644

YAMAKAWA, H. (see also SHIMADA, J.). 319 YANG-YEN, H.-F., SUBRAHMANYAM, C. S., CASSIDY, S. &

ROTHBLUM, L. I., Characterization of rat ribosomal DNA II. Identification of the highly repetitive DNA in the 3’ non- transcribed spacer, 389

YARUS, M. (see also RAFTERY. L. A.), 343 YASUDA, S. (see also MATSUI, M.), 529 Yeast aspartic acid tRNA, crystallographic refinement, 119 Yeast or Escherichia coli tRIJAASP, studies of self-association,

and of their interactions with Escherichia roli tRNA”“; anticodon-anticodon interactions in solution, 107

Yeast tRNAASP tertiary structure in solution and areas of interaction of the tRNA with aspartyl-tRNA synthetase. Comparative study of yeast phenylalanine system by phosphate alkylation experiments with ethylnitrosourea.

- 4,5n Yeast transformation with linearized plasmid DNA. Formation

of inverted dimers and recombinant plasmid products. 375 YI, Q.-M., ROCKENBACH, S., WARD, J. E., Jr & LUTKENHAUS, J..

Structures and expression of the cell division ,genesjtsQ. ftsA andjts2. 399

YODA. K. (see also KITANI, T.), 45

ZENTGRAF, H. (see also MBLLER, G.), 367 Z-line, narrow, small square (SS) net structure. 644 Z-lines. vertebrate muscle, fine structure. Model and computer

simulation of Z-line archit,ecture. 621