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Context Aware interactions for diagnosis of Bipolar Disorder

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Conference presentation at the Ubicom Workshop Ubiwell 2007
16
Innsbruck, September 16 th D. Tacconi, B. Arnrich On the Feasibility of Using Activity Recognition and CA On the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder On the Feasibility of Using On the Feasibility of Using Activity Recognition and Activity Recognition and Context Aware Context Aware Interaction to Support Early Interaction to Support Early Diagnosis of Bipolar Diagnosis of Bipolar Disorder Disorder UbiWell Workshop UbiWell Workshop Innsbruck, 16 Innsbruck, 16 th th September 2007 September 2007
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Page 1: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

On the Feasibility of Using Activity On the Feasibility of Using Activity Recognition and Context AwareRecognition and Context Aware

Interaction to Support Early Diagnosis Interaction to Support Early Diagnosis of Bipolar Disorderof Bipolar Disorder

UbiWell WorkshopUbiWell Workshop

Innsbruck, 16Innsbruck, 16thth September 2007 September 2007

Page 2: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

David Tacconi, Oscar Mayora, CREATE-NET

Paul Lukowicz, University of Passau

Bert Arnrich, Gerhard Tröster, ETH Zurich

Christian Haring, PSYCHIATRIC STATE HOSPITAL TIROL (PSHT)

Paper ContributorsPaper Contributors

PSHTPSYCHIATRIC STATE HOSPITAL TIROL

Page 3: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

OutlineOutline

MotivationBipolar disorder and System RequirementsPervasive computing to support Bipolar

Disorder diagnosisA proposed System ArchitectureConclusion

Page 4: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

MotivationMotivation Global Burden of Disease

Mental illness accounts for over 15% of the burden of diseases in established market economies (source World Health Organization, World Bank, Harvard University)

Disability Adjusted Life Years (DALYs): Measure the lost years of healthy life (premature death or

disability) Depression:

is the most common psychiatric disorder, accounting for 50.8 million DALYs or 10.7% of the global burden of disease

It is ranked fourth among all causes of DALYs and is the leading nonfatal condition globally

Bipolar disorder: account for another 14,1 million (3.0%) DALYs

Page 5: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

MotivationMotivation Few technological solutions exist to aid people

affected by mental illness. Obvious reasons are:

people affected by mental illness are more likely to have problems dealing with complex technology

providing behavioral assistance is much more difficult than providing physical assistance

solutions require considerable amount of domain specific knowledge and can only be developed in close cooperation with psychiatrists

Page 6: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

MotivationMotivation In this work:

we identify Bipolar Disorder as a condition that can realistically benefit from behavioral monitoring,

we identify support in early detection of imminent transitions between normal, manic and depressed states as the specific contribution to therapy,

we identify specific behaviors that need to be detected by the proposed system, using the so called Hamilton Depression Scale (HAMD) and Bech-Rafaelsen Mania scale (BRMS), which are generally accepted tools in the diagnosis of depression and mania,

based on literature study and previous work by the authors, we argue that detecting these specific behaviors is feasible,

we propose an appropriate system architecture based on existing devices and previous systems implemented by the authors groups

Page 7: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Bipolar DisorderBipolar Disorder Bipolar disorder

repeated relapses of mania and depression Recurrence rates are high at around 50% at one year and 70% at

four years Treatments for Bipolar disorder:

Pharmacotherapy is the main treatment nowadays Alternative: teach the patients to recognize and manage Early

Warning Signs (EWS) Diagnosing through patient questionnaires:

for depression the Hamilton Depression Scale (HAMD) for mania the Bech-Rafaelsen Mania Scale (BRMS). Both contain a series of questions related to patients’ activities and

feelings

Page 8: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Bipolar Disorder: Mania SymtomsBipolar Disorder: Mania Symtoms Manic Episode

Increased energy, activity, and restlessness Excessively "high," overly good, euphoric mood Extreme irritability Racing thoughts and talking very fast, jumping from one idea to another Distractibility, can't concentrate well Little sleep needed Unrealistic beliefs in one's abilities and powers Poor judgment Spending sprees A lasting period of behavior that is different from usual Increased sexual drive Abuse of drugs, particularly cocaine, alcohol, and sleeping medications Provocative, intrusive, or aggressive behavior Denial that anything is wrong

Page 9: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Bipolar Disorder: Depression SymptomsBipolar Disorder: Depression Symptoms Lasting sad, anxious, or empty mood Feelings of hopelessness or pessimism Feelings of guilt, worthlessness, or helplessness Loss of interest or pleasure in activities once enjoyed, including

sex Decreased energy, a feeling of fatigue or of being "slowed down" Difficulty concentrating, remembering, making decisions Restlessness or irritability Sleeping too much, or can't sleep Change in appetite and/or unintended weight loss or gain Chronic pain or other persistent bodily symptoms that are not

caused by physical illness or injury Thoughts of death or suicide, or suicide attempts

Page 10: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Bipolar Disorder: the HAMDBipolar Disorder: the HAMD1. Depressed Mood2. Feelings of Guilty3. Suicide4. Insomnia (early)5. Insomnia (middle)6. Insomnia (late)7. Work and Activities8. Retardation:

Psychomotor9. Agitation10. Anxiety (Psychological)

11. Anxiety Somatic12. Somatic Symptoms

(Gastrointestinal)13. Somatic Symptoms

General14. General Symptoms15. Hypocondriasis16. Loss of Weight17. Insight18. Diurnal Variation19. Depersonalization and

Derealization20. Paranoid Symptoms

Page 11: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Pervasive Computing for diagnosis of BDPervasive Computing for diagnosis of BD From our experience and a literature study, we propose to

look at the following parameters: HAMD:

items 4,5,6 (insomnia) 7 (work and activities) 8 (psychomotoric retardation) 9 (agitation) 10, 11(anxiety)

BRMS: items 1 (motoric activities) 2 (verbal activities) 4 (voice-noise level) 8 (contacts) 9 (sleep)

Page 12: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Diagnosis 1/3Diagnosis 1/3

Insomnia and Sleep disorders (HAMD 4-6, BRMS 9):

Page 13: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Diagnosis 2/3Diagnosis 2/3

Verbal activities (BRMS 2, 4) and Contacts/Conversation (BRMS 8)

Page 14: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

Diagnosis 3/3Diagnosis 3/3

Activity Recognition (HAMD 7,8,9,10,11, BRMS 1)

Page 15: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

System ArchitectureSystem Architecture

Page 16: Context Aware interactions for diagnosis of Bipolar Disorder

Innsbruck, September 16th D. Tacconi, B. Arnrich

On the Feasibility of Using Activity Recognition and CAOn the Feasibility of Using Activity Recognition and CA Interaction to Support Early Diagnosis of Bipolar Disorder Interaction to Support Early Diagnosis of Bipolar Disorder

ConclusionConclusion


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