© 2016 University of Utah Updated June 21, 2017

Paper Transcription & Translation: Cut-outsCopy Instructions

Make single-sided copies of the cut-outs.• There are 5 versions of page A; each codes for a different protein.• Give each student or pair of students one version of page A and a copy of page B.

Tips • Make color copies of the Transcription and Translation machinery (page B) and laminate them so

that they may be re-used.

• Copy each version of page A on a different color of paper so that students don’t mix up their DNA, mRNA, and protein strips.

To make one long strip each of DNA and mRNA, tape the shorter pieces together end to end.

© 2016 University of Utah Updated June 21, 2017

Paper Transcription & Translation: Cut-outs

A1

END

mR

NA

1 2

1 2 Protein

M

TE

MP

LATE

S

TR

AN

D

DN

A: G

ene 1 CGCCGCCACGATGTTGGAGCTGCGGCTTGTGC

GCACAAGCCGCAGCTCCAACATCGTGGCGGCG

CTGATTGCCATCAGT

AGGGGAGCCTCCTCAAGAAGGTCCTGGAGGCGATCCG

CGGATCGCCTCCAGGACCTTCTTGAGGAGGCTCCCCT

ACTGATGGCAATCAG

© 2016 University of Utah Updated June 21, 2017

Paper Transcription & Translation: Cut-outs

A2

END

TE

MP

LATE

ST

RA

ND

1 2

1 2DN

A: G

ene 2

mR

NA

Protein

M

TAGAGAGACTATCGGACCATGGCGCCCA

TGGGCGCCATGGTCCGATAGTCTCTCTA

GTCAGATTCAGGGTGAGAGAGCC

TGCACGAAGAGGACTGTAAACTGGAGGCAAGCGCTGT

ACAGCGCTTGCCTCCAGTTTACAGTCCTCTTCGTGCA

GGCTCTCTCACCCTGAATCTGAC

© 2016 University of Utah Updated June 21, 2017

Paper Transcription & Translation: Cut-outs

A3

END

TE

MP

LATE

ST

RA

ND

1 2

1 2DN

A: G

ene 3

mR

NA

Protein

M

TATAGTCAAATATCACAATTGTTAAATG

CATTTAACAATTGTGATATTTGACTATA

ACCTCCCAATTTATTCATAATTCTTTAAATTAATT

ATAACCTTCATATATTTCTTTGGCAATATCATCTATT

AATAGATGATATTGCCAAAGAAATATATGAAGGTTAT

AATTAATTTAAAGAATTATGAATAAATTGGGAGGT

© 2016 University of Utah Updated June 21, 2017

Paper Transcription & Translation: Cut-outs

A4

ENDT

EM

PLAT

E S

TR

AN

D

1 2

1 2DN

A: G

ene 4

mR

NA

Protein

M

AAGACCATGGTTCGCTTTAGCATGGGTA

TACCCATGCTAAAGCGAACCATGGTCTT

AAGCTCTTGTCATCGTTGAGTCCCCGGCAAAAGCCAA

TTGGCTTTTGCCGGGGACTCAACGATGACAAGAGCTT

TCCGAATTACTTGTTGATCGTT

AACGATCAACAAGTAATTCGGA

© 2016 University of Utah Updated June 21, 2017

Paper Transcription & Translation: Cut-outs

A5

END

TE

MP

LATE

ST

RA

ND

1 2

1 2DN

A: G

ene 5

Protein

M

mR

NA

TCGTGGGCTGTTATATCCGCATGTCAGA

TCTGACATGCGGATATAACAGCCCACGT

TATGGATTCGAGGATTAAATTTACCAA

CCTTGCAAACTCAGAAAAGTATTATGATGAGGACCCA

TGGGTCCTCATCATAATACTTTTCTGAGTTTGCAAGG

TTGGTAAATTTAATCCTCGAATCCATA

© 2016 University of Utah B

Paper Transcription & Translation: Cut-outs

Updated June 21, 2017

TRANSCRIPTION machine(RNA polymerase)

mRNA

TEMPLATESTRAND

mRNA

TRANSLATION machine(Ribosome)