Pathology News Vol. 7 #10 October 2000 Publishing Info Pathology News Department of Pathology, Richardson Labs Queen’s University, Kingston, Ontario K7L 3N6 Canada http://www.path.queensu.ca/ Published monthly, Circulation 160 For article submissions please see last page We publish only that which is submitted! (There are no expense accounts and no reporters) If there is no news about your area that means we haven’t received any! F rom the Head Effective October 1, 2000, John Rossiter has succeeded Dr. Sam Ludwin as Program Director, Neuropathology as well as the Head of Neuropathology, a subunit of the Anatomic Pathology Division. Welcome to Harriet Feilotter (now located on Douglas3) F or Your Information Queen´s pension plan posts 20-per-cent return Queen's Pension Plan members will see their Money Purchase accounts increase by more than 20 per cent this year, thanks in large part to this year's top performing equity market, the Toronto Stock Exchange. As well, Queen's retirees can expect to see their pensions increase by slightly more than 8 per cent as a result of the post-retirement indexing formula that is built into the Queen´s plan. Details coming up in the Oct. 10 Gazette. Yay! Early Retirement here we come! Retirement of Dr. J. Kennedy Dr. Jim Kennedy, a long-time member of the Department of Pathology, retired on June 30 th , 2000. For those of you who do not know Jim, he is a man of eclectic interests, not given to following a crowd, or joining a band wagon, but a man of individual thought. This is reflected in the way he led his life and how he pursued his research interests.
Published monthly, Circulation 160For article submissions please see last page
We publish only that which is submitted! (There are noexpense accounts and no reporters) If there is no newsabout your area that means we haven’t received any!
From the Head
Effective October 1, 2000, John Rossiter has succeededDr. Sam Ludwin as Program Director, Neuropathology aswell as the Head of Neuropathology, a subunit of theAnatomic Pathology Division.
Welcome to Harriet Feilotter (now located on Douglas3)
For Your Information
Queen´s pension plan posts 20-per-cent returnQueen's Pension Plan members will see their MoneyPurchase accounts increase by more than 20 per cent thisyear, thanks in large part to this year's top performing equitymarket, the Toronto Stock Exchange.As well, Queen's retirees can expectto see their pensions increase byslightly more than 8 per cent as a resultof the post-retirement indexing formulathat is built into the Queen´s plan.Details coming up in the Oct. 10 Gazette.
Yay! Early Retirement here we come!
Retirement of Dr. J. Kennedy
Dr. Jim Kennedy, a long-time member of theDepartment of Pathology, retired on June 30th, 2000. Forthose of you who do not know Jim, he is a man of eclecticinterests, not given to following a crowd, or joining a bandwagon, but a man of individual thought. This is reflected inthe way he led his life and how he pursued his researchinterests.
2 Pathology News October 2000
Dr. Kennedy completed his undergraduate andmedical degrees at the University of Toronto, the latterin 1961, and he subsequently completed a PhD inMedical Biophysics in 1966. After two years as aNational Cancer Institute of Canada postdoctoralresearch fellowship, held at the Salk Institute forBiological Studies in San Diego, California, Jim joinedthe Department of Pathology at Queen’s University andsubsequently the Kingston Regional Cancer Center atKGH as a Senior Scientist where he pursued aremarkable research career.
His early interests were in the role that theimmune system played in the development andprogression of malignancies. In the early 1980s heabruptly changed direction (a repeating theme in Dr.Kennedy’s research career which resulted in thenickname “grasshopper”) and began to examine thepossibility of using protoporphyrins as a tool for thetreatment of malignancies. This idea came to Jim afterhe recognized that porphyrins had neurotoxic properties,the mechanisms which may have been due to cellularphotosensitization from one of the porphyrin metabolites.Although this did not seem to be a popular idea withothers, Dr. Kennedy and Dr. Roy Pottier (a colleague atthe Royal Military College) developed photodynamictherapy as early as 1987. The advantages of the photo-therapeutic approach were the treatment’s immediateeffects in killing tumour cells, the good cosmetic results,and the lack of any systemic side effects. Photodynamictherapy is now used the world over to detect and treatcancers of the gastrointestinal, respiratory and urogenitaltracts, in addition to a variety of primary and secondarymalignancies and pre-malignant conditions of the skin.
Q u e e n ’ sUniversity patentedthis technique andlicensed it to DUSAPharmaceuticalswhere it has recentlybeen approved bythe US Food andDrug Administrationfor the treatment of
actinic keratoses. This commercial success is yet anotherexample of taking a novel basic research idea and as theresults emerge, being astute enough to recognize thetherapeutic potential without having originally explored theidea specifically to develop it for therapeutic purposes.
Although Dr. Kennedy’s research activities will besignificantly diminished during his retirement, he plans tocontinue providing his services to patients who require them.
The Department wishes Jim and his family happyretirement years and continuing success with his clinicalactivities.
Submitted by: Dr. R. Kisilevsky
Updated equity guide now available The Guide to Equity Resources at Queen´s has beenupdated and is now available on the web. Staff, faculty andstudents can consult the guide for current equity resources ongender, racism, equity policies and other diversity topics.The updated guide was the project of Queen´s studentShannon Dent, who worked with Human Resources thissummer to research and format the web-based information.
Applications for Sabbatical and Academic LeaveApplications for all members of faculty (clinical and QUFAbargaining unit members) are due in the Faculty Office byMonday, October 30th, 2000. Application forms areavailable from Barb in Dr. Manley’s office.
Milestones15 years
3 Pathology News October 2000
Patricia FalknerDavid Lillicrap
ConvocationFaculty are encouraged to attend the Faculty of HealthSciences convocation on October 26, 2000 at 2:00pm to be held in Grant Hall.
Canada Saving Plan for Queen’s EmployeesHuman Resources has the 2001 Canada Saving Planapplications and Employee Plan Change forms.Employees already enrolled and who do not wish tomake any changes to their deduction amounts, do notneed to do anything - contributions will continue asbefore. Those who want to make changes to theirexisting plans - e.g. increase/decrease contributionamounts - will need to complete an Employee PlanChange form. Employees wishing to open a new planwill need to fill out an application form. Employeeswishing to discontinue their plans, need to send a memoto the HR department. The first payroll deduction foremployees making additions/changes, will take place inDecember and will be reflected on December’s salaryadvice slips.
If making changes or enrolling for the first time, thecompleted forms should be returned to the HRdepartment no later than October 27, 2000.
Applications and Employee Plan Change forms can bepicked up in the HR Department main office,Richardson Hall.
Congratulations toAwardsLloyd Kennedy who received the RSA Prentice Awardfor Excellence in Teaching.
Jason Sack and Tim Childs who jointly received theRSA Prentice Award for the best presentation by apathology resident.
Funding Received
Dr. David Lillicrap, Laboratory Centre for Disease ControlHealth Canada, 2000-2003A National Hemophilia Mutation Testing Program
Dr. David Lillicrap, Bayer/CBSPartnership Fund, 2000-2002Inhibitor development following factor VIII genetherapy: Evaluation of a mouse model
Drs. David Lillicrap, Mike Nesheim, Marlys Koschinsky,Graham Cote, Don Maurice and David Lee, Heart andStroke Foundation of Ontario, 2000-2005Collaborative studies of hemostasis, fibrinolysis, andvascular cell growth and function
Publications
A Single Nucleotide Polymorphism at Nucleotide- 1793 in the von Willebrand Factor (VWF)
Regulatory region is Associated with Plasma VWF:AgLevelsPhilip Harvey, Angela Keightley, Y. Miu Lam, CherieCameron and David LillicrapBritish Journal of Haematology 109:349-353, 2000.
The Factor VIII Acute Phase Response Requires theParticipation of NfkB and C/EBPMegan Begbie, Colleen Notley, Shawn Tinlin, Lisa Sawyer,David LillicrapThromb. Haemost. 84:216-22, 2000.
4 Pathology News October 2000
Alumni Corner
A Tribute to Dr. G.F. Kipkie
It was a delightful, rare and treasured vignette ofthe Department of pathology as it first developed, wascarefully nurtured, and flourished. The ivy coveredwalls, so to speak, were laid bare to show off thestrength of the foundation stones laid so long ago.
Pathologists, at least the Queen’s ones seem tolast a long time and weather well. So it was that onSeptember 12, 2000, an illustrious group ofdepartmental members current and past, came togetherto recognize in a formal way the contributions of theDepartment of Dr. G.F. (Bud) Kipkie. For some 30years the Director of the Laboratories, it is unlikely thatanyone will come close to matching that feat certainly ina Teaching Tertiary Care Hospital. That it was Bud’s85th birthday seemed irrelevant and certainly inaccuratea measure of age. For although he sported a walkingstick, one was not sure that it was used for walking as atleast at one point he was about to challenge Bob Moreto a fencing match.
Ably chaired by the current Chairman PaulManley, a succession of prior Heads and Chairsreminisced about past days. Bob More spoke of thecritical necessity to get the right man for the job and ofthe matching strengths of the two of them in the earlydays. Howie Steele was an integral part of thedepartment and Bud and Howie were close colleagues.Howie was unable to be present but good wishes andthoughts were passed on.
Nate Kaufman took over the reins and with Budmanaging the lab, recruited many of the members (somenow retired) that moved Queen’s to front and centre onthe Canadian and NorthAmerican maps as a place to train.
David Robertson noted quite rightly how important itwas to have been in Saskatchewan. Bud had been the
Director of Labs at the Grey Nuns, a job my father held formany years, a generation or so later.
Several spoke to Bud’s skill as a teacher.Punctuality was expected and it still, by the way, is anassessment point on the In-Training Evaluation Report forresidents. Bob Kisilevsky and Bill Corbett reflected on theirtimes of training with Bill providing a dramatic one-actrendition of the intra-operative consults - knife and all. BothBobs, More and Kisilevsky spoke to the gruffness of Bud,but as you knew the man better, slowly one realized twothings. Firstly, it meant no nonsense and straight forwardtalk - no flim-flam was tolerated. Secondly, behind all thatwas a kind and considerate man who respected you, whowas concerned for you and would help you. Al Fletcher, ofmy generation, reiterated these points and recalled some ofKipkie’s “Rules of Pathology”. Sam Ludwin spoke warmlyof his working relationship and noting the respect due to anAlfisti (owner of an Alfa Romeo). Daria Haust recalled theearly days and the setting up of the residency programme toinclude clinical pathology.
So it was on such a backdrop of warm words andremembered memories, that Bud stepped to the lectern.
Quietly and graciously with prodigious recall hedescribed the earlier years, the challenges, the rewards andthe generations of friendships. A few corrections to the priorstories were made but not many. It was a time of the rightpeople, working together, seizing the opportunities anddeveloping over the decades a strong multipotentialdepartment recognized for its teaching, its diagnostic skills,its research and its role through various members in thedevelopment of pathology in Canada. Bud was,unbeknownst to many one of the founding members of theCanadian Association of Neuropathologists although heclaimed never to have paid dues. Sam Ludwin reaffirmed hewas still a member! Bud acknowledged how much help andsupport he has from Mack. We did determined by nefariousmeans, and with Mack’s help, that Bud does enjoy musicbut one was not fully clear on the full meaning of the GeorgeFrederick (Kipkie) or (Handel).
The finale was the presentation of a truly magnificentphotographic portrait of Bud which now hangs on Douglas2 right outside the secretarial pool. He can keep an eye on
5 Pathology News October 2000
things - he probably has a deal with his ‘old’ secretaryCarolyn - just to make sure those surgical reports areright.
It is too late now of course, but Bud wasrenowned for looking at the slide with the naked eye andthen, diagnosis half made, would confirm it with a rapidpass through at low power. Use of the high powerobjective was frowned upon! But....did anyone checkall those objectives on Bud’s microscope? If the theoryis right there should have been only one!
From your colleagues and friends of many yearsa warm Happy Birthday and perhaps a simple andheartfelt thank you from all those present, and from allthose whose life you have touched. Thank you Bud.
Submitted by: Dr. D. Dexter(see pictures on next page)
Letters from individuals who were unable to attend:Dear Bud:
Happy Birthday! I had hoped to be in Kingstonto greet you but unfortunately another old codger, myfather, decided to visit us. As you are a relative chickenby his standards, he is 3 years your senior, he had totake priority! Seriously, I am really sorry that I could notbe with you to join in the roasting. The latter would notbe complete without me reminding the new recruits tothe department that the first question I got in myrecruitment interview with you was “Why is McMasterkicking you out?”! Even the twinkling eyes thataccompanied the question would not make thatpolitically correct in 2000!
Anyway, if they did kick me out (I am not sureI ever answered your question!) it was probably the bestthing that ever happened to me after meeting Hilary.There are so many fond memories but certainly high onthe list was your retirement dinner and the preparationswe put into the cabaret in your honor. I still havenightmares that I am being lectured by Sam Ludwin thatmy tendency to ad lib was all very well for me but it wassomewhat difficult for the other members of the ‘cast’ toknow exactly where they were! It is difficult to believethat this was twenty years ago but you will be pleased to
know that I am now the owner of a ‘Carte Senior’ whichentitles me, amongst other things, to 50% reductions on alltrain and plane fares in France! So age does have itscompensations!
Well I must be brief as I am sure this is only one ofmany salutations. Again I am sorry I could not actually bethere. I would have loved to see those twinkling eyes as Idelivered my loving insults. Thank you for all that you did forme. Thank you for the fun we always had. Keep the golfclub swinging until we do have the chance to get togetheragain. Hilary sends her love. You will be pleased to knowthat she has become a golfing addict. That means that I havebecome a golfing widower. I keep her in her place byreminding her that it was me that won the department’sDuffer Trophy. I can’t remember when that was but MikeRaymond will confirm that I am not lying!
With love from both of us and wishing you manyhappy returns Yours sincerely, Alan R Giles MD, FRCP(C)
Card from Dr. Santosh Wasan:Dear Dr. Kipkie:
We wish we could wish you a very happy birthdayin person, but our commitments in Toronto do not allow usto leave from here. Our thoughts and good wishes are withyou and we wish you a joyful happy 85th birthday.
Toshi & MadanA Thank you from Dr. B. Kipkie to Dr. Manley:
“Dear Paul:Thank you very much for your efforts on my behalf.
I did appreciate it very much.I must admit I don’t remember doing or saying the
things I was accused of but I expect there wasn’t muchexaggeration.
It was great seeing members of the department andagain please accept my thanks.
Sincerely, Bud”
6 Pathology News October 2000
A Tribute to Dr. G.F. Kipkie
7 Pathology News October 2000
Dr. Dexter’s Corner
GENES AND ROTTEN SOCKS: THEPSEUDOMONAS STORY
Two small articles in recent Lancets, (356:918and 356:613-614, 2000), deal with our old enemyPseudomonas aeruginosa. The earlier commentarybemoans the burdensome disease of cystic fibrosis (CF)and the almost inevitable link to colonization and infectionby Pseudomonas. An unfortunate outcome of thesummer camps for children and young adults with CF isthat, in addition to bringing together children with similarchallenges, so does it allow for the sharing of resistantbacterial organisms. Pseudomonas is a chief offender. Not only can it become rapidly resistant to a multitude ofantibiotics, it can also indulge in the phenomenon of"quorum sensing". For anyone who has chairedcommittees over the years, this is a valuable skill and hasallowed much university and hospital business to proceedin the absence of real numbers and physical presence ofmembers (the Virtual Committee). So, too, is thisprocess similar for the Pseudomonas. For when thepopulation is low, individuals stop producing a number ofkey virulence factors as if hiding or laying low to escapedetection. But as their numbers increase, they begin tobehave in a coordinated fashion, surrounding themselvesin a slimy matrix that acts as a shield from antibodies,complement, and cellular armies, all the while releasingslews of destructive enzymes and virulence factors.
Our usual approach in patients with CF is to treatacute exacerbations with antibiotics, but there is evidencethat more intense and regular antibiotics dosing may bemore effective including intrapulmonary therapy.
A third article in Nature, 406:959-964, providesinsight and understanding and, perhaps, the opportunityfor new treatment strategies. The genome ofPseudomonas has been deciphered (6.3 million basepairs). Researchers were "stunned" at the size andcomplexity. Following three years work by acollaboration from the University of Washington,PathoGenesis, and the US Cystic Fibrosis Foundation,the following picture emerged.
A large number of genes were involved inregulation (command control) and a large number ofpump systems were identified. Both these featuresindicated much redundancy, but also provided asophisticated, remarkably high level of rapid adaptation. Quite simply, while many antibiotics should or would killthe organism, the ability and action of any or many of 10-12 drug efflux systems, ensure the toxic challenge israpidly neutralized and removed. Further, the ability ofthe bug to move and exist in a wide range of micro-environments, may be attributed to multiple (at least four)mobility systems. It is not surprising that the altered lungand its pathology in cystic fibrosis offers an environmentin which Pseudomonas may linger, survive, and thrive andbe so difficult to treat.
What one had not realized, is the evolutionalcomplexity of this microbe. It is not dumb. It has geneticcomplexity approaching yeast, and its genome is about40 percent of the size of Drosophila melanogaster (fruit-fly). But when all is said and done, knowledge of thePseudomonas genome does help explain its pathologyand possible future therapy. What of the human genomeproject? We should expect similar benefits.
David F. Dexter, MD
8 Pathology News October 2000
Clinical News
Ana Cachaco is the first brave soul to movefrom the wilds of Doran2 into the wonders of civilizedDouglas4! The rest of the people/lab/equipment will bemoving over around the end of October and earlyNovember. Welcome!
Just a reminder to all KGH staff that rollerblades arenot to be used while inside the hospital. Also, bicyclesare not permitted in the hospital. We ask that you usethe bike racks provided at the main entrance and theWatkins parking lot.Thank you for your cooperation.Tom Davis, Acting Manager Security Services
Grants and Such
Grants have grown to such a huge pageof the newsletter that we have split them
off into a separate supplement to the newsletter. Allresearchers & faculty will receive the supplement as wellas any one else who wants it. Otherwise the rest of thesubscribers get everything but.
There are 18 pages for October.These are available on our web site:http://www.path.queensu.ca/pathnews/grants.htm
Don’t Want No Worms in Me (A Blues Song)
Parasites in my water, parasites in my food, I’d tell you where there’s more, but its really just too rude.You can get them when you travel, they’re not extra, it’s allfor freeBetter take your medication, don’t want no worms in me.
ChorusThe worms are out to get you, On this planet far and wide,Doesn’t matter where you go,There is no place to hide!
Camping in the backwoods, drinking from a mountain stream,I felt things move inside me, God, This isn’t just a dream,That pain, a Cramp, it hit me, nearly dropped me to my knees, I had the trots, I had the runs, don’t want no worms in me.
Their eggs were here before us, They’ll be here when we’re all doneI hope my insides stay nice and cleanCause parasites are no fun!
People say the water in this province is quite sage for you todrinkI can tell that you’re a fool if that’s really what you thinkYou’ll have to find a washroom, you need it now you see,Your nightmare has just started, don’t want no worms in me!
The worms are out to get you, On this planet far and wide,Doesn’t matter where you go,There is no place to hide!
There’s tapeworms in your piggies, there’s tapeworms in yourbeef,You cook them well that’s all, if you want to skip the grief.If you’re sick, you call the doctor, ask them how much for thefeePay them anything at all, cause don’t want no worms in me.
Their eggs were here before us, They’ll be here when we’re all doneI hope my insides stay nice and cleanCause parasites are no fun!
Submitted by Jim Gauthier
Richardson ResearchSeminars 2000Tuesdays at 4:00 pm, RichardsonAmphitheatre, Richardson Laboratory
9 Pathology News October 2000
Date Speaker
October 17, 2000 Dawei Zhang, PhD Student
October 24, 2000 Dr. Xiang-Jiao Yang Montreal
October 31, 2000 Dr. Bruce Elliott
November 7, 2000 Suzie Abu-Abed, PhD Student
November 14, 2000 Dr. Virginia Walker
November 21, 2000 Annie Killoran, MSc Student
November 28, 2000 Dr. Patricia Tonin, McGill Univ.
December 5, 2000 Dr. Moira Glerum, U. ofAlberta
December 12, 2000
December 19, 2000 No seminar
Undergraduate News
A whole pile (well, two or three) of facultyhave been using electronic presentationmethods (Corel Presentations and
Microsoft Powerpoint) to create lectures, present them inclass, and are now making them available on our website.This last bunch are related to the Phase I medical studentcourses.
We have room for more!
Please note that the Library hasinstalled Exambank onto a new, morepowerful server.This means a new URL:
http://130.15.161.50/exambank/
Please update your bookmarks and any links you mayhave on any of your departmental websites - also pleasesend this note to departmental staff for information. Thanks, Cindy Price
Ggraduate News
Congratulations to Leah Young, whosuccessfully defended her PhD thesis onSeptember 15th.
Ontario Graduate Scholarships application booklets areavailable from Barb Saunders or the School of GraduateStudies. Deadline for submission to the Department is October 30, 2000.
10 Pathology News October 2000
Jason Sack, co-winner (with T. Childs) of theRSA Prentice Award for Residents, and LloydKennedy repeat winner of the RSA PrenticeAward for Excellence in Teaching. In thebackground is Dr. Monique Arquint, a recentappointment to the Pathology Attending Staff.
Postgraduate News
Jobs Available
Ontario HIV Treatment NetworkAssociate Director for Science - HIVInformation Infrastructure Project
They are seeking an established scientist with ademonstrated ability to develop an independent researchprogram in HIV. The candidate must have an establishedrecord of excellence in research related to HIV data sets. An MD or PhD degree with at least 3-5 years of relevantpost-doctoral experience is expected. The idealcandidate will have a demonstrated aptitude forcollaborative research, a demonstrated ability tocommunicate with researchers from a variety ofdisciplines and with other community stakeholders. Knowledge of an experience with research involvingcohort and observational data, and knowledge of andsensitivity to the community and social issues involved inHIV research would be valuable. Our ideal candidatewill have experience with mentoring of junior, student orcommunity researchers, experience with strategies forresearch dissemination, and will have demonstratedleadership, planning supervisory and team-building skills. This is a half-time position with a competitive salary andbenefit package in a dynamic environment. A full job
description and additional information about the OHTNand HIIP, may be found at www.ohtn.on.caPlease forward your resume by October 6, 2000, via faxor e-mail only to: The Ontario HIV Treatment Network,1300 Yonge Street, Suite 308, Toronto, Ontario M4T1X3. Fax: 416-640-4245; e-mail: [email protected]
University of Iowa Health CareThis position is for a MD or PhD scientists with a recordof productivity and is open to candidates at any rank. The successful applicant will be expected to implement astrong extramurally funded research program focussed onmolecular aspects of apoptosis. Preference will be givento those applicants studying epithelial cells and/or cancerbiology. The selected applicant will receive a primaryappointment in the Department of Pathology, withopportunities for secondary appointments in otherdepartments and programs. The Cancer Centre at theUniversity of Iowa is an NCI-designated Cancer Centerwhich fosters a collaborative and supportive environmentamong both basic and clinical scientists. Applicantsshould submit curriculum vitae, research plans, and thenames of three references to: Vicki Brown, Departmentof Pathology, University of Iowa College of Medicine,1117 Med Labs. Iowa City, IA 52242. For informationor questions, call 319) 335-8232.
University of ColoradoThe Department of Pathology at the University ofColorado Health Sciences Center has several facultyopenings for qualified MDs or MD/PhDs in the SurgicalPathology and Cytopathology Services. One of thepositions will be filled by a candidate with interest inGI/Liver Pathology. The candidates should have post-residency training and interest in developing researchactivities, training residents/fellows and teaching medicalstudents. Rank and salary are commensurate withqualifications. Submit a CV, cover letter describinginterests and a list of three references to: L. E. Gerschenson, MD, PhD, Professor and Chair ofPathology, University of Colorado School of Medicine,4200 E. Ninth Avenue, Box B216, Denver, CO 80262
The George Washington University Medical Center The Department of Pathology at the George Washington
11 Pathology News October 2000
University Medical Center is seeking a new Director ofits Transfusion Service/Blood Bank. The GWU MedicalCenter is a growing institution located in the heart of thenation's capital, with expanding clinical and academicprograms and ongoing construction of a totally newstate-of-the-art hospital facility. The Transfusion Servicesupports a Level 1 trauma center, high-risk obstetricalservice, bone marrow transplant program, and the fullrange of other clinical services. Academic rank will be atthe Instructor, Assistant, or Associate Professor level.Applicants should be board certified or eligible in CP orAP/CP, with special training and/or experience intransfusion medicine. Board certification or eligibility intransfusion medicine is highly desirable. The successfulcandidate will be expected to contribute to the totalmission of the department - quality service, productiveresearch, and effective teaching. Participation in on-callactivities in clinical pathology will be required, andopportunities to provide other pathology services will bemade available depending on the interest and experienceof the candidate. Review of applications will begin onOctober 1, 2000, and continue until the position is filled.Please send curriculum vitae and the names of threereferences to: Donald Karcher, M.D., Department ofPathology, the George Washington University MedicalCenter, 901 23rd Street, N.W., Washington, DC20037. Phone: 202-715-4659; Fax: 202-715-4691; E-mail: [email protected]
University of SaskatchewanApplications are invited for an Assistant
Professor, tenure track faculty position. Responsibilitiesinclude undergraduate and resident teacing, and serviceprimarily to the Royal University Hospital. The candidateshould be eligible for or hold certification in anatomical inAnatomical Pathology/General Pathology from theRCPSC, and be eligible for licensure in Saskatchewan. The candidate should have a defined commitment to apersonal research program. Preference will be given tothose with certification in AP and interest/experience inone or more areas of AP. Applications with CV andnames of three referees should be submitted, no later than4 December 2000 to: Dr. K.L. Massey, Professor andHead, Department of Pathology, Royal UniversityHospital, 103 Hospital Drive, Saskatoon, Saskatchewan.
The Queen’s Gazette is nowavailable online the web in adobe acrobat format... thereis a link on our Dept. home page to http://advancement.queensu.ca/html/gazette.html
Our Web server had a major operating systemupgrade over Thanksgiving weekend. CDServer1 and the KGH gateway servers will followlater this month.
Server stability:Web Server 11:57am up 19 daysCD Server 11:50am up 92 daysKGHGate 11:50am up 73 daysWould it that our Windows NT servers were so stable!
Email Traffic:Remember when I used to post the amount of email inand out of the department for the last month?Well, I haven’t done that for over a year or so andthought I would revisit it.
September 1996: 6307September 1998: 11403September 1999: 17005September 2000: 20605 pieces of email in and out, andin general, they are getting bigger as more and morepeople send more and larger attachments.
12 Pathology News October 2000
Web Server Usage Summary 2000 Feb01-Oct04
Please distribute the following message throughout yourdepartment:==================================Computing Workshops through InformationTechnology Services
The following non-credit, hands-on workshops areavailable for registrations from Queen's faculty, staff andstudents.
Oct 20, Excel Charts (level=intermediate), 9:30-11:30amOct 23, Intro to PowerPoint (level=basic), 1:30-4pmOct 27, Intro to HTML (level=basic), 9:30am-noonOct 30, PowerPoint Beyond the Basics, 1:30-4pmNov 3, HTML Layout & Design (level=intermediate),9:30-11:30am
Registration is required for all workshops and can bedone via the on-line registration system located on theITS Education webpage:
http ://noteswww.queensu.ca/ITS/itscourses4.nsf
Article SubmissionsSUBMISSION DATE: Pathology News will be mailed to all
faculty, housestaff, graduate students, and anyone whorequests it on the Friday following the first Monday of themonth. The next deadline date for submission will be MondayNovember 6
Send items (in order of preference) by: 1) email, 2)floppy disk, 3) paper mail, or 4) FAX.
Engineering Conversions that have been used inPathology
1. Ratio of an igloo's circumference to its diameter:Eskimo Pi2. 2000 pounds of Chinese soup: Won ton3. 1 millionth of a mouthwash: 1 microscope4. Time between slipping on a peel and smacking thepavement: 1 bananosecond5. Weight an evangelist carries with God: 1 billigram6. Time it takes to sail 220 yards at 1 nautical mile perhour: Knot-furlong7. 365.25 days of drinking low-calorie beer becauseit's less filling: 1 lite year8. 16.5 feet in the Twilight Zone: 1 Rod Serling9. Half of a large intestine: 1 semicolon10. 1000 aches: 1 kilohurtz11. Basic unit of laryngitis: 1 hoarsepower12. Shortest distance between two jokes: A straightline (think about it for a moment)13. 453.6 graham crackers: 1 pound cake14. 1 million microphones: 1 megaphone15. 1 million bicycles: 2 megacycles16. 2000 mockingbirds: two kilomockingbirds (workon it....) 17. 10 cards: 1 decacards18. 1 kilogram of falling figs: 1 Fig Newton19. 1000 cubic centimeters of wet socks: 1 literhosen20. 1 millionth of a fish: 1 microfiche21. 1 trillion pins: 1 terrapin22. 10 rations: 1 decoration23. 100 rations: 1 C-ration24. 2 monograms: 1 diagram25. 8 nickels: 2 paradigms26. 3 statute miles of I.V. surgical tubing at Yale UnivHospital: One I.V. League27. 100 Senators: Not 1 decision
