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Cranial Nerves1

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    Cranial nerve nucleiCranial nerve nuclei

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    1.general somatic afferent,GSA ( from skin)

    2.general visceral afferent,GVA( from blood vessels,glands etc)

    3.general somatic efferent,GSE(SE) (to skeletal muscles of

    somitic origin)

    Functional componentsFunctional components

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    Functional componentsFunctional components

    4.general visceral efferent,GVE(motor

    fibres to smooth muscles and glands)

    5.special somatic

    afferent,SSA(vision,audition)

    6.special visceral

    afferent,SVA(taste)(smell)

    7.special visceral efferent,SVE(all the

    muscles derived from pharyngeal arches)

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    Olfactory nerve(I)Olfactory nerve(I)

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    Functional componentFunctional component

    It has only one componentIt has only one component

    SVA(special visceral afferent)SVA(special visceral afferent)

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    Olfactory nerveOlfactory nerve

    The olfactory system consists ofThe olfactory system consists of

    the olfactory epithelium, bulb and tractthe olfactory epithelium, bulb and tract

    olfactory areas of the brain collectivelyolfactory areas of the brain collectivelyknown as the rhinencephalon.known as the rhinencephalon.

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    Olfactory bulb

    I. Olfactory:

    Sensorynerves forsmell

    U

    http://images.google.com/imgres?imgurl=http://staff.harrisonburg.k12.va.us/~mwampole/0-projects/every-body/body-nose.jpg&imgrefurl=http://staff.harrisonburg.k12.va.us/~mwampole/0-projects/every-body/nose.htm&h=215&w=212&sz=10&tbnid=DVe1CeqpQq4TWM:&tbnh=101&tbnw=99&hl=en&start=34&prev=/images%3Fq%3Dolfactory%2Bnerve%26start%3D20%26svnum%3D10%26hl%3Den%26lr%3D%26sa%3DN
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    The olfactory epithelium is located

    in the roof, superior conchae, and

    septum of the nasal cavity.

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    Olfactory receptor cells arebipolar neurons

    The olfactory bulb

    is an enlargement of the rostral

    end of the olfactory tract.

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    the olfactory tract divides into

    the lateral, intermediate, and

    medial Striae

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    Fibers from the pyriform cortex project to the

    entorhinalcortex(Brodmann area 28),

    which contains an olfactory association area thatsends projections to the hippocampus.

    This portion of the limbic system is undoubtedly

    associated

    with the learning of likes&dislikes of foods.

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    Olfactory projections

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    TEST1.assessment of the patency of the

    nostrils.

    Each nostril is examined separately.The test involves occlusion of a single

    nostril while the eyes of the patient are

    closed.

    http://www.eustatiantube.org/clinic/neuroexam/cranialmovies/odorants.asfhttp://www.eustatiantube.org/clinic/neuroexam/cranialmovies/odorants.asf
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    The patient should inhale gently through

    the open nostril in close proximity to a

    common odorant

    (e.g., vanilla, ground coffee, fresh

    orange, etc.).The patient should be asked first whether

    the odorant can be detected.

    If detectable, the odorant should be

    identified by name.

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    If the patient fails at the task, the test

    should be repeated with at least one

    distinct odorant.

    The test should be repeated for the

    opposite nostril using entirely new

    odorants.

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    Optic nerve(II)Optic nerve(II)

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    Functional component:Special somatic afferent(SSA)

    Arises from the retina.Passes through the optic canals

    to enter the cranial cavity and

    decussates with its fellow

    to form the optic chiasm.

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    It then continues as optic tract

    to reach Lateral geniculatebody and from here

    it continues as optic radiation

    to end in the visual cortex.

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    Each optic nerve contains nasal andtemporal fibers.

    The nasal fibers decussate in the chiasm

    so that

    each optic tract contains temporal fibers

    of the same side

    and nasal fibers of the opposite side.

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    http://ect.downstate.edu/courseware/haonline/imgs/00000/3000/600/3612.jpg
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    sphenoid

    Arrows in optic canals

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    The Visual Pathway from Below

    Optic nerveOptic chiasmOptic tractLateral geniculate bodyOptic radiation

    Visual cortexSuperior colliculus of themidbrainPutamenLong association bundle -inferior occipitofrontal fasciculus

    Pulvinar of the thalamusCalcarine fissurePoster inferior horn of thelateral ventricle

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    http://www.aph.org/cvi/brain_2.pdf
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    Complete blind

    hemianopia

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    Various hemianopias

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    The test is completed by askingthe patient to read a Snellen eye

    chart viewed at 20 feet.

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    Oculomotor nerve(III)Oculomotor nerve(III)

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    Has a motor nucleus in the midbrain

    (at superior colliculus)

    which supplies all the extra ocular muscles

    except

    Lateral rectus and superior oblique.

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    It also has a parasympathetic

    nucleus(Edinger-westphal)

    Which supplies sphincter pupillae

    and ciliaris mucles.

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    Functional components;

    1.Somatic efferent.(SE)

    2.General visceral

    efferent(GVE)

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    Course;

    Passes through the mid brain to emerge

    in the interpeduncular fossa.

    Passes through the lateral wall of the cavernous sinus

    Enters the orbit throughsuperior orbital fissures middle compartment.

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    Divides into upper and lowerdivisions

    Supply

    Levator palpebrae

    superioris,superior,inferior,medial recti

    and inferior oblique muscles of theeye.

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    Nucleus of III nerve

    Ts of midbrain at the level of superior colliculus

    Middle cranial fossa

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    Arrow indicates cavernous sinus

    Middle cranial fossa

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    III

    IV

    V1

    V2V3

    Structures in the lateral wall of cavernous sinus

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    The Cavernous Sinuses

    A. Carotid Artery

    B. TrochlearNerve

    C. MaxillaryNerve

    D. Abducens

    Nerve

    E. SphenoidSinus

    F. Pituitary Gland

    G. Cavernous

    Sinus

    H. OphthalmicNerve

    I. OculomotorNerve

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    Superior orbital fissure

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    Bony orbit(RT) viewed from front

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    Clinical aspects( ptosis)Clinical aspects( ptosis)

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    Trochlear nerve (IV)Trochlear nerve (IV)

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    Functional component:somatic efferent SE

    Supply:superior oblique muscle of the eye

    Nucleus:situated in the midbrain

    at the level of inferior colliculus

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    Its the only cranial nerve to emerge

    from the dorsal aspect of the

    brain stem(rest all emerge from the

    ventral aspect).

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    It is the only cranial nerve

    that decussates with its fellow.

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    Passes through the lateral wall of the

    cavernous sinus

    below the III nerve and above the

    ophthalmic nerve.

    Enters the orbit through the lateral part ofsup.orb.fissure.

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    It then passes medially to supply

    the superior oblique.

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    Nucleus of IVnerve in the midbrainNucleus of IVnerve in the midbrain

    (inferior collicular level)(inferior collicular level)

    V

    D

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    IV nerve

    Cavernous sinus

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    Rt orbit(superior view)

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    Damage to the

    Trochlear nerve will

    present as:

    Extorsion (outward

    rotation) of the affected

    eye due to the unopposed

    action of the inferior

    oblique muscle.

    .The patient will

    compensate by moving

    his head to intort the

    contra lateral eye.

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    Vertical diplopia (double vision)

    due to the extorted eye.

    Weakness of downward gaze mostnoticeable on medially-directed eye.

    This is often reported as difficulty

    in descending stairs.

    What is torsion?What is torsion?

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    What is torsion?What is torsion?

    It is defined as rotation of an imaginaryIt is defined as rotation of an imaginary

    point at 12o clock position on the cornealpoint at 12o clock position on the corneal

    margin. If it moves externally(temporally) itmargin. If it moves externally(temporally) it

    is called extorsion.is called extorsion. If it moves internally(nasally),it is calledIf it moves internally(nasally),it is called

    intorsion.intorsion.

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    Extorsion of the left eye(IVnerve palsy)

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    Abducent nerve(VI)Abducent nerve(VI)

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    Functional component:somatic efferent SE

    Supplies lateral rectus only.

    Nucleus: in the floor of the IV ventricle

    deep to facial colliculus

    Facial nerve fibers loop around this.

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    Facial colliculus

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    emerges at the interpeduncular

    fossa in line with IIInerve.

    Passes through the cavernous

    sinus inferolateral to ICA.

    Course:

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    Enters the orbit through the

    middle compartment,between the

    two divisions of IIInerve and ends

    by supplying lateral rectus.

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    At the interpeduncular fossaIn the cranial cavity

    VI

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    III

    III

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    Showing the relationship withShowing the relationship with

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    Showing the relationship withg p

    circle of Willscircle of Wills

    IIInerve

    VI nerve

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    Injury to Abducens nerve causes

    the paralysis of ipsilateral lateral rectus.

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    The eye is drawn medially due

    to

    unopposed action of medial

    rectus.

    This will result indiplopia(double vision)

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    Strabismus the inability to direct both eyes to the same object.

    Rt abducens palsy(no abduction)

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    p y( )

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    Testing of III,IV,VI nerves

    III Oculomotor Eye movement

    upward,

    downward, and

    inward; narrowing

    (constriction) orwidening (dilation)

    of the pupil in

    response to

    changes in light

    The ability to move each eye

    upward, downward, and inward

    is tested by asking the person to

    follow a target moved by the

    examiner. The upper eyelid ischecked for drooping (ptosis).

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    IV Trochlea

    r

    Eye

    movement

    downward

    and inward

    The ability to move

    each eye downward

    and inward is tested by

    asking the person to

    follow a target movedby the examiner.

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    VI Abduc

    ens

    Side-to-

    side

    (lateral)eye

    movement

    The ability to move

    each eye outward

    beyond the midlineis tested.


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