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Cranial nerve nucleiCranial nerve nuclei
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1.general somatic afferent,GSA ( from skin)
2.general visceral afferent,GVA( from blood vessels,glands etc)
3.general somatic efferent,GSE(SE) (to skeletal muscles of
somitic origin)
Functional componentsFunctional components
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Functional componentsFunctional components
4.general visceral efferent,GVE(motor
fibres to smooth muscles and glands)
5.special somatic
afferent,SSA(vision,audition)
6.special visceral
afferent,SVA(taste)(smell)
7.special visceral efferent,SVE(all the
muscles derived from pharyngeal arches)
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Olfactory nerve(I)Olfactory nerve(I)
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Functional componentFunctional component
It has only one componentIt has only one component
SVA(special visceral afferent)SVA(special visceral afferent)
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Olfactory nerveOlfactory nerve
The olfactory system consists ofThe olfactory system consists of
the olfactory epithelium, bulb and tractthe olfactory epithelium, bulb and tract
olfactory areas of the brain collectivelyolfactory areas of the brain collectivelyknown as the rhinencephalon.known as the rhinencephalon.
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Olfactory bulb
I. Olfactory:
Sensorynerves forsmell
U
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The olfactory epithelium is located
in the roof, superior conchae, and
septum of the nasal cavity.
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Olfactory receptor cells arebipolar neurons
The olfactory bulb
is an enlargement of the rostral
end of the olfactory tract.
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the olfactory tract divides into
the lateral, intermediate, and
medial Striae
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Fibers from the pyriform cortex project to the
entorhinalcortex(Brodmann area 28),
which contains an olfactory association area thatsends projections to the hippocampus.
This portion of the limbic system is undoubtedly
associated
with the learning of likes&dislikes of foods.
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Olfactory projections
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TEST1.assessment of the patency of the
nostrils.
Each nostril is examined separately.The test involves occlusion of a single
nostril while the eyes of the patient are
closed.
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The patient should inhale gently through
the open nostril in close proximity to a
common odorant
(e.g., vanilla, ground coffee, fresh
orange, etc.).The patient should be asked first whether
the odorant can be detected.
If detectable, the odorant should be
identified by name.
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If the patient fails at the task, the test
should be repeated with at least one
distinct odorant.
The test should be repeated for the
opposite nostril using entirely new
odorants.
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Optic nerve(II)Optic nerve(II)
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Functional component:Special somatic afferent(SSA)
Arises from the retina.Passes through the optic canals
to enter the cranial cavity and
decussates with its fellow
to form the optic chiasm.
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It then continues as optic tract
to reach Lateral geniculatebody and from here
it continues as optic radiation
to end in the visual cortex.
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Each optic nerve contains nasal andtemporal fibers.
The nasal fibers decussate in the chiasm
so that
each optic tract contains temporal fibers
of the same side
and nasal fibers of the opposite side.
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sphenoid
Arrows in optic canals
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The Visual Pathway from Below
Optic nerveOptic chiasmOptic tractLateral geniculate bodyOptic radiation
Visual cortexSuperior colliculus of themidbrainPutamenLong association bundle -inferior occipitofrontal fasciculus
Pulvinar of the thalamusCalcarine fissurePoster inferior horn of thelateral ventricle
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Complete blind
hemianopia
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Various hemianopias
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The test is completed by askingthe patient to read a Snellen eye
chart viewed at 20 feet.
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Oculomotor nerve(III)Oculomotor nerve(III)
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Has a motor nucleus in the midbrain
(at superior colliculus)
which supplies all the extra ocular muscles
except
Lateral rectus and superior oblique.
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It also has a parasympathetic
nucleus(Edinger-westphal)
Which supplies sphincter pupillae
and ciliaris mucles.
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Functional components;
1.Somatic efferent.(SE)
2.General visceral
efferent(GVE)
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Course;
Passes through the mid brain to emerge
in the interpeduncular fossa.
Passes through the lateral wall of the cavernous sinus
Enters the orbit throughsuperior orbital fissures middle compartment.
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Divides into upper and lowerdivisions
Supply
Levator palpebrae
superioris,superior,inferior,medial recti
and inferior oblique muscles of theeye.
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Nucleus of III nerve
Ts of midbrain at the level of superior colliculus
Middle cranial fossa
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Arrow indicates cavernous sinus
Middle cranial fossa
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III
IV
V1
V2V3
Structures in the lateral wall of cavernous sinus
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The Cavernous Sinuses
A. Carotid Artery
B. TrochlearNerve
C. MaxillaryNerve
D. Abducens
Nerve
E. SphenoidSinus
F. Pituitary Gland
G. Cavernous
Sinus
H. OphthalmicNerve
I. OculomotorNerve
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Superior orbital fissure
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Bony orbit(RT) viewed from front
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Clinical aspects( ptosis)Clinical aspects( ptosis)
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Trochlear nerve (IV)Trochlear nerve (IV)
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Functional component:somatic efferent SE
Supply:superior oblique muscle of the eye
Nucleus:situated in the midbrain
at the level of inferior colliculus
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Its the only cranial nerve to emerge
from the dorsal aspect of the
brain stem(rest all emerge from the
ventral aspect).
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It is the only cranial nerve
that decussates with its fellow.
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Passes through the lateral wall of the
cavernous sinus
below the III nerve and above the
ophthalmic nerve.
Enters the orbit through the lateral part ofsup.orb.fissure.
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It then passes medially to supply
the superior oblique.
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Nucleus of IVnerve in the midbrainNucleus of IVnerve in the midbrain
(inferior collicular level)(inferior collicular level)
V
D
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IV nerve
Cavernous sinus
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Rt orbit(superior view)
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Damage to the
Trochlear nerve will
present as:
Extorsion (outward
rotation) of the affected
eye due to the unopposed
action of the inferior
oblique muscle.
.The patient will
compensate by moving
his head to intort the
contra lateral eye.
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Vertical diplopia (double vision)
due to the extorted eye.
Weakness of downward gaze mostnoticeable on medially-directed eye.
This is often reported as difficulty
in descending stairs.
What is torsion?What is torsion?
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What is torsion?What is torsion?
It is defined as rotation of an imaginaryIt is defined as rotation of an imaginary
point at 12o clock position on the cornealpoint at 12o clock position on the corneal
margin. If it moves externally(temporally) itmargin. If it moves externally(temporally) it
is called extorsion.is called extorsion. If it moves internally(nasally),it is calledIf it moves internally(nasally),it is called
intorsion.intorsion.
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Extorsion of the left eye(IVnerve palsy)
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Abducent nerve(VI)Abducent nerve(VI)
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Functional component:somatic efferent SE
Supplies lateral rectus only.
Nucleus: in the floor of the IV ventricle
deep to facial colliculus
Facial nerve fibers loop around this.
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Facial colliculus
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emerges at the interpeduncular
fossa in line with IIInerve.
Passes through the cavernous
sinus inferolateral to ICA.
Course:
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Enters the orbit through the
middle compartment,between the
two divisions of IIInerve and ends
by supplying lateral rectus.
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At the interpeduncular fossaIn the cranial cavity
VI
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III
III
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Showing the relationship withShowing the relationship with
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Showing the relationship withg p
circle of Willscircle of Wills
IIInerve
VI nerve
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Injury to Abducens nerve causes
the paralysis of ipsilateral lateral rectus.
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The eye is drawn medially due
to
unopposed action of medial
rectus.
This will result indiplopia(double vision)
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Strabismus the inability to direct both eyes to the same object.
Rt abducens palsy(no abduction)
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p y( )
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Testing of III,IV,VI nerves
III Oculomotor Eye movement
upward,
downward, and
inward; narrowing
(constriction) orwidening (dilation)
of the pupil in
response to
changes in light
The ability to move each eye
upward, downward, and inward
is tested by asking the person to
follow a target moved by the
examiner. The upper eyelid ischecked for drooping (ptosis).
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IV Trochlea
r
Eye
movement
downward
and inward
The ability to move
each eye downward
and inward is tested by
asking the person to
follow a target movedby the examiner.
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VI Abduc
ens
Side-to-
side
(lateral)eye
movement
The ability to move
each eye outward
beyond the midlineis tested.