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CTO in Europe

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Industry Assembly 6 th European Live Summit on Retrograde CTO Revascularization April 28-29, 2017 - Zurich, Switzerland Course Directors Course Vice Director & Coordinator Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC Thomas F. Luscher, MD, FACC, FESC George Sianos, MD, PhD, FESC CTO in Europe Alfredo R. Galassi MD, FESC, FACC, FSCAI Department of Clinical and Experimental Medicine, University of Catania, Italy and University Heart Center, University Hospital Zurich, Switzerland
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Page 1: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

CTO in Europe

Alfredo R. Galassi MD, FESC, FACC, FSCAI

Department of Clinical and Experimental Medicine,

University of Catania, Italy and

University Heart Center, University Hospital Zurich, Switzerland

Page 2: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

0

50

100

150

200

1321

29 33 38 43 52 55 61

124

143

182

Club Membership

Full

0

10

20

30

40

50

60

70

80

90

100

63

92

3

13

Associate

Non-European

Associate

Non-European

Affiliate

Page 3: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

Page 4: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

0 10 20 30 40 50 60 70

from 0 to 9

from 10 to49

50+

2016 2015

Case #

Members #

Associate Members

Page 5: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

Online Registry 2008 – 2016

Full Members

Associate Members

Page 6: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

Antegrade/Retrograde Operators

Full Members

Associate Members

0%

20%

40%

60%

80%

100%

2008 2009 2010 2011 2012 2013 2014 2015 2016

50

31 28.620.5 18.8 14.6 16.6

5.5 7.2

50

69 71.479.5 81.2 85.4 83.4

94.5 92.8

Antegrade only Retrograde + Antegrade

0%

20%

40%

60%

80%

100%

2015 2016

19.5 20

81.5 80

Page 7: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

Antegrade/Retrograde Procedures

Full Members

Associate Members

0%

20%

40%

60%

80%

100%

2008 2009 2010 2011 2012 2013 2014 2015 2016

90 88.5 89.5 8677 71 72.4

64.9 67.2

10 11.5 10.5 1423 29 27.6

35.1 32.8

Antegrade Retrograde± Antegrade

0%

20%

40%

60%

80%

100%

2015 2016

76.3 76.7

23.7 23.3

Page 8: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

Angiographic Success

Full Members

Associate Members

0

20

40

60

80

100

2008 2009 2010 2011 2012 2013 2014 2015 2016

85.5 86.5 88.1 87.6 87.8 90.387 89 89

73.6

64.2

77.1 76.5 77.879.5 82.2 83.3

81.2

Antegrade Retrograde

0

20

40

60

80

100

2015 2016

8.891.3

78.181.2

Page 9: CTO in Europe

Industry Assembly

6th

European Live Summit on

Retrograde CTO Revascularization

April 28-29, 2017 - Zurich, Switzerland

Course Directors Course Vice Director & Coordinator

Alfredo R. Galassi , MD, FACC, FESC Oliver Gaemperli, MD, FESC

Thomas F. Luscher, MD, FACC, FESC

George Sianos, MD, PhD, FESC

0

0.5

1

1.5

2

2.5

3

3.5

2008 2009 2010 2011 2012 2013 2014 2015 2016

0

0.5

1

1.5

2

2.5

3

3.5

4

2015 2016

Full members

Associate members

Death Cardiac tamponade

Myocardial infarction Vascular complication

Coronary perforation Donor vessel dissection

Page 10: CTO in Europe

0

10

20

30

40

50

60

2011

2012

2013

2014

2015

2016

Wires to start

%

Page 11: CTO in Europe

0

5

10

15

20

25

30

35

2011

2012

2013

2014

2015

2016

Final wires to cross

%

Page 12: CTO in Europe

Guiding Catheter Selection in the ERCTO

No trend differences were observed between antegrade

and retrograde approach during years

0

10

20

30

40

50

60

70

2008 2009 2010 2011 2012 2013 2014 2015 2016

6 Fr 7 Fr 8 Fr

Page 13: CTO in Europe

Procedural Details

0

10

20

30

40

50

60

70

80

2008 2009 2010 2011 2012 2013 2014 2015 2016

Contralateral injection Radial approach

Page 14: CTO in Europe

40.338.3

2.30.9

0

10

20

30

40

50

2015 2016

Corsair Tornus

Corsair / Tornus

%

Page 15: CTO in Europe

Cross Boss / Stingray

3.7

2.22.7

2.4

0

2

4

6

8

10

2015 2016

Cross Boss Stingray

%

Page 16: CTO in Europe

2.3

3.2

0

2

4

6

8

10

2015 2016

Rotablator

%

Rotational Atherectomy

Page 17: CTO in Europe

Guiding Extension

%

11.7 12.1

0

5

10

15

20

2015 2016

Page 18: CTO in Europe

Dual Lumen Microcatheter

%

7.7

9.7

0

5

10

15

20

2015 2016

Page 19: CTO in Europe

0

5

10

15

20

25

30

2009 2010 2011 2012 2013 2014 2015 2016

32

5

7.9 7.3 6.7

12 12.6

1 1

6

17.6

22.8 22.7

27.2

23.6

2.4 2.1

5

10.311.8

11.1

17.3

14.6

Antegrade Retrograde Overall

IVUS

%

Page 20: CTO in Europe

Revascularization strategies

according to J-CTO score 2016

98.2 9485

75.570.2 69.4

1.8 615

24.529.8 31.6

0

20

40

60

80

100

0 1 2 3 4 5

Conventional wire escalation Dissection re-entry

P<0.05

%

Page 21: CTO in Europe

94.294.9

83.7 85.5

74.470.2

79.9

93.990.5

86.6

81.6

73.2

82.5

94.791.7

87.7

79.1

68.4

0

20

40

60

80

100

0 1 2 3 4 5

2014 2015 2016

Success according to J-CTO score

2014 p<0.05

2015 p=NS

2016 p=NS

%

Page 22: CTO in Europe

Case Selection Guided by the J-CTO Score

Harding SA, Tsuchikane E et al. JACC Intv in press

Page 23: CTO in Europe

13.1 11.8 9.1

2619.8 19.6

26.727.1 30

22.324.9 24.8

9.5 13.4 13.9

2.4 3 2.7

0%

20%

40%

60%

80%

100%

2014 2015 2016

0 1 2 3 4 5

J-CTO score during years

Page 24: CTO in Europe

Angiographic Success Vs J-CTO score

Page 25: CTO in Europe

EURO CTO CLUB

Krakow 2016

Zurich

2017

THANK YOU

FOR YOUR PARTICIPATION

Berlin

2017


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