European Life Sciences Infrastructure for Biological Information www.elixir-europe.org

Niklas Blomberg, ELIXIR Director

18 December 2013

Current and future plans for ELIXIR

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medicine

environment

bioindustries

society

To build a sustainable European infrastructure for biological information, supporting life science research and its translation to:

ELIXIR’s mission

The Challenge in Life Sciences

• Data

• Standards

• Tools

• Compute

• Training

• Industry

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The Challenge in Life Sciences

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• Data

• Standards

• Tools

• Compute

• Training

• Industry

A distributed infrastructure to scale with the challenge

ELIXIR data infrastructure for Europe’s life science research sector ELIXIR Nodes build local bioinformatics capacity throughout Europe ELIXIR Nodes build on national strengths and priorities

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ELIXIR Status

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ECA signed:

MoU signed:

Announcing today:

Belgium

New building for ELIXIR Hub now open

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ELIXIR Pilot: Identifying new drug targets

The Human Protein Atlas portal is a publicly available database with millions of high-resolution images showing the spatial distribution of proteins in 46 different normal human tissues and 20 different cancer types, as well as 47 different human cell lines. http://www.proteinatlas.org

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Interoperability of high-resolution protein data at EMBL-EBI and HPA, Sweden

Acceleration towards sustained operations

• Key objectives: • In 2014: Build on success of Interim Phase, formal establishment of

Nodes

• In 2015: Start delivering ELIXIR services, sustain BioMedBridges services

• From 2016 onwards: sustained operations across ELIXIR

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Industry and Innovation

• Challenge to access and understand services

• EU wide engagement programme - Build on strong local interactions through Nodes!

• Small companies – Big Data

• ELIXIR Cloud for SMEs

• EFPIA and IMI

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ELIXIR Programme

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A Life-science infrastructure of interoperable and integrated data-services

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HPA Gene Ontology UniProt

Europe PMC EGA Expression Atlas

Will the improvement we see in an

LPS-challenged mouse translate to

a measurable clinical benefit?

user data

Data interoperability, vocabulary and ontology services

BioMedBridges Ten new biomedical sciences research infrastructures stronger through common links

• Computational ‘data and service’ bridges between the BMS RIs

• Interoperability between data and services in the biological, medical, translational and clinical domains

• Link basic biological research data with clinical research and associated data

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Future challenges for life-science data services

Scale and Sustain funding

Distributed infrastructure with >1M users

Algorithms to data – clouds, research environments…

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European Life Sciences Infrastructure for Biological Information www.elixir-europe.org

Safeguarding the results of life science research in Europe

ELIXIR

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