+ All Categories
Home > Documents > Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United...

Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United...

Date post: 21-Feb-2021
Category:
Upload: others
View: 1 times
Download: 0 times
Share this document with a friend
20
United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health Metrics and Evaluation In the last week, the increase in daily cases has become much clearer, and for the first time since early August, daily deaths have begun to rise. We believe that the fall/winter surge has begun, albeit several weeks behind the massive surge in Europe. The fall/winter surge will intensify in November and December, reaching a peak in January. Many states will face enormous pressure on hospital capacity and will likely have to re-impose some social distancing mandates. The best strategy to delay re-imposition of mandates and the associated economic hardship is to expand mask use. Current situation Daily cases have increased to nearly 50,000 a day in the last week up from 45,000 a day last week (Figure 1). Daily deaths are up to 710 a day in the last week an increase from 680 a day last week. This is the first increase in daily deaths since early August (Figure 2). Effective R computed on the basis of cases, hospitalizations, and deaths is over 1 in many Northern states, but also in Nevada, Colorado, New Mexico, Kansas, Oklahoma, Mississippi and Alabama (Figure 3). The daily death rate is over 4 per million in eight states spanning from Montana to Florida (Figure 6). Trends in key drivers of transmission (mobility, mask use, testing, and seasonality) Social distancing mandates remain largely unchanged over the last week with the exception of re-imposition of some gathering restrictions in Pennsylvania (Figure 7). Only one social distancing mandate remains in place in Florida, Idaho, Missouri, Oklahoma, and South Dakota. Mobility remains constant at the national level. Only California and Hawaii have levels that are less than 35% of the pre-COVID-19 baseline (Figure 8). Approximately two-thirds of Americans are wearing a mask outside the home, and this level has remained constant over the last two weeks (Figure 9). The lowest mask use rates are in Wyoming, North Dakota, and South Dakota. Testing rates continue to rise since the first week of September, which is likely due to both increasing numbers of individuals with symptoms seeking testing and mandatory testing in some workplaces and educational facilities (Figure 10). Projections In our reference scenario the scenario that we think is most likely to happen we expect daily deaths to reach nearly 2,200 a day in mid-January (Figure 13). Cumulative deaths by February 1 in the reference scenario reach 386,000 (Figure 12). The reference scenario assumes re-imposition of social distancing mandates when the daily death rate reaches 8 per million in many states beginning with Montana and North Dakota in October, six states in November, 13 states in December, and five states in January (Figure 15). Expanding mask use to 95%, the level seen in Singapore, can greatly delay the imposition of mandates and save 63,000 lives (Figure 12). Figure 18 compares our forecasts with other publicly archived models. The USC (SIKJalpha) model shows an increase in death reaching a peak in mid-November. The Imperial model has nearly flat daily deaths through to mid-January. MIT (Delphi) and Los Alamos National Labs continue to forecast steady declines in daily deaths to lower levels. Given US cases and deaths have started to increase, we expect many of these other models to revise their forecasts up in the next 13 weeks.
Transcript
Page 1: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States Model updates for October 22, 2020

covid.healthdata.org Institute for Health Metrics and Evaluation

In the last week, the increase in daily cases has become much clearer, and for the first time since early August, daily deaths have begun to rise. We believe that the fall/winter surge has begun, albeit several weeks behind the massive surge in Europe. The fall/winter surge will intensify in November and December, reaching a peak in January. Many states will face enormous pressure on hospital capacity and will likely have to re-impose some social distancing mandates. The best strategy to delay re-imposition of mandates and the associated economic hardship is to expand mask use.

Current situation

• Daily cases have increased to nearly 50,000 a day in the last week up from 45,000 a day last week (Figure 1).• Daily deaths are up to 710 a day in the last week an increase from 680 a day last week. This is the first increase

in daily deaths since early August (Figure 2).• Effective R – computed on the basis of cases, hospitalizations, and deaths – is over 1 in many Northern states,

but also in Nevada, Colorado, New Mexico, Kansas, Oklahoma, Mississippi and Alabama (Figure 3).• The daily death rate is over 4 per million in eight states spanning from Montana to Florida (Figure 6).

Trends in key drivers of transmission (mobility, mask use, testing, and seasonality)

• Social distancing mandates remain largely unchanged over the last week with the exception of re-imposition ofsome gathering restrictions in Pennsylvania (Figure 7). Only one social distancing mandate remains in place inFlorida, Idaho, Missouri, Oklahoma, and South Dakota.

• Mobility remains constant at the national level. Only California and Hawaii have levels that are less than 35% ofthe pre-COVID-19 baseline (Figure 8).

• Approximately two-thirds of Americans are wearing a mask outside the home, and this level has remainedconstant over the last two weeks (Figure 9). The lowest mask use rates are in Wyoming, North Dakota, andSouth Dakota.

• Testing rates continue to rise since the first week of September, which is likely due to both increasing numbersof individuals with symptoms seeking testing and mandatory testing in some workplaces and educationalfacilities (Figure 10).

Projections

• In our reference scenario – the scenario that we think is most likely to happen – we expect daily deaths to reachnearly 2,200 a day in mid-January (Figure 13).

• Cumulative deaths by February 1 in the reference scenario reach 386,000 (Figure 12).• The reference scenario assumes re-imposition of social distancing mandates when the daily death rate reaches 8

per million in many states beginning with Montana and North Dakota in October, six states in November, 13states in December, and five states in January (Figure 15).

• Expanding mask use to 95%, the level seen in Singapore, can greatly delay the imposition of mandates and save63,000 lives (Figure 12).

• Figure 18 compares our forecasts with other publicly archived models. The USC (SIKJalpha) model shows anincrease in death reaching a peak in mid-November. The Imperial model has nearly flat daily deaths through tomid-January. MIT (Delphi) and Los Alamos National Labs continue to forecast steady declines in daily deaths tolower levels. Given US cases and deaths have started to increase, we expect many of these other models torevise their forecasts up in the next 1–3 weeks.

Page 2: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States Model updates for October 22, 2020

covid.healthdata.org Institute for Health Metrics and Evaluation

Model updates

• There are no major updates the modeling strategy this week. We continue to examine a wide range of datasources including infection-fatality rates calculated from seroprevalence surveys, hospital-fatality rates, andselect individual hospital record databases to determine whether the age-specific infection-fatality rate hasdeclined.

• We are elaborating our model to allow for including the impact of vaccination scale-up in the first and secondquarters of 2021.

IHME wishes to warmly acknowledge the support of these and others who have made our COVID-19 estimation efforts possible. Thank you.

For all COVID-19 resources at IHME, visit http://www.healthdata.org/covid.

Questions? Requests? Feedback? Please contact us at https://www.healthdata.org/covid/contact-us.

Page 3: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America SUMMARY OF FINDINGS

COVID-19 Results Briefing: United States o f America

Institute for Health Metrics and Evaluation (IHME)

October 22, 2020

This briefing contains summary i nformation on t he l atest projections f rom t he IHME model on COVID-19 in United States of America. The model was run on October 20, 2020.

Model updates

Updates to the model this week include additional data on deaths, cases, and updates on covariates.

Summary of findings

covid19.healthdata.org 1 Institute for Health Metrics and Evaluation

Page 4: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CURRENT SITUATION

Current situation

Figure 1. Reported daily COVID-19 cases

0

20,000

40,000

60,000

Feb Mar Apr May Jun Jul Aug Sep OctMonth

Cou

nt

Daily cases

covid19.healthdata.org 2 Institute for Health Metrics and Evaluation

Page 5: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CURRENT SITUATION

Table 1. Ranking of COVID-19 among the leading causes of mortality this week, assuming uniform deathsof non-COVID causes throughout the year

Cause name Weekly deaths RankingIschemic heart disease 10,724 1COVID-19 4,962 2Tracheal, bronchus, and lung cancer 3,965 3Chronic obstructive pulmonary disease 3,766 4Stroke 3,643 5Alzheimer’s disease and other dementias 2,768 6Chronic kidney disease 2,057 7Colon and rectum cancer 1,616 8Lower respiratory infections 1,575 9Diabetes mellitus 1,495 10

Figure 2a. Reported daily COVID-19 deaths.

0

1,000

2,000

Feb Mar Apr May Jun Jul Aug Sep Oct

Dai

ly d

eath

s

covid19.healthdata.org 3 Institute for Health Metrics and Evaluation

Page 6: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CURRENT SITUATION

Figure 2b. Estimated cumulative deaths by age group

0

5

10

15

<5 10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95 99Age group

Sha

re o

f cum

ulat

ive

deat

hs, %

Figure 3. Mean effective R on October 08, 2020. The estimate of effective R is based on the combinedanalysis of deaths, case reporting and hospitalizations where available. Current reported cases reflect infections11-13 days prior so estimates of effective R can only be made for the recent past. Effective R less than 1means that transmission should decline all other things being held the same.

<0.91

0.91−0.93

0.94−0.95

0.96−0.97

0.98−0.99

1−1.01

1.02−1.03

1.04−1.05

1.06−1.08

>=1.09

covid19.healthdata.org 4 Institute for Health Metrics and Evaluation

Page 7: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CURRENT SITUATION

Figure 4. Estimated percent of the population infected with COVID-19 on October 19, 2020

<1

1−3.9

4−6.9

7−10.4

10.5−13.4

13.5−16.4

16.5−19.4

19.5−22.4

22.5−25.4

>=25.5

Figure 5. Percent of COVID-19 infections detected. This is estimated as the ratio of reported COVID-19cases to estimated COVID-19 infections based on the SEIR disease transmission model.

0

20

40

Mar Apr May Jun Jul Aug Sep Oct

Per

cent

of i

nfec

tions

det

ecte

d

Republic of Korea Germany Italy United Kingdom United States of America

covid19.healthdata.org 5 Institute for Health Metrics and Evaluation

Page 8: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CURRENT SITUATION

Figure 6. Daily COVID-19 death rate per 1 million on October 19, 2020

<1

1 to 1.9

2 to 2.9

3 to 3.9

4 to 4.9

5 to 5.9

6 to 6.9

7 to 7.9

>=8

covid19.healthdata.org 6 Institute for Health Metrics and Evaluation

Page 9: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CRITICAL DRIVERS

Critical drivers

Table 2. Current mandate implementation

All

gath

erin

gs r

estr

icte

d

All

none

ssen

tial b

usin

esse

s cl

osed

Any

bus

ines

ses

rest

ricte

d

Mas

k us

e

Sch

ool c

losu

re

Sta

y ho

me

orde

r

Trav

el li

mits

WyomingWisconsin

West VirginiaWashington

VirginiaVermont

UtahTexas

TennesseeSouth Dakota

South CarolinaRhode IslandPennsylvania

OregonOklahoma

OhioNorth Dakota

North CarolinaNew York

New MexicoNew Jersey

New HampshireNevada

NebraskaMontanaMissouri

MississippiMinnesota

MichiganMassachusetts

MarylandMaine

LouisianaKentucky

KansasIowa

IndianaIllinoisIdaho

HawaiiGeorgiaFlorida

District of ColumbiaDelaware

ConnecticutColoradoCaliforniaArkansas

ArizonaAlaska

Alabama

Mandate in place No mandate

covid19.healthdata.org 7 Institute for Health Metrics and Evaluation

Page 10: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CRITICAL DRIVERS

Figure 7. Total number of social distancing mandates (including mask use)

WyomingWisconsin

West VirginiaWashington

VirginiaVermont

UtahTexas

TennesseeSouth Dakota

South CarolinaRhode IslandPennsylvania

OregonOklahoma

OhioNorth Dakota

North CarolinaNew York

New MexicoNew Jersey

New HampshireNevada

NebraskaMontanaMissouri

MississippiMinnesota

MichiganMassachusetts

MarylandMaine

LouisianaKentucky

KansasIowa

IndianaIllinoisIdaho

HawaiiGeorgiaFlorida

District of ColumbiaDelaware

ConnecticutColoradoCaliforniaArkansas

ArizonaAlaska

Alabama

Feb Mar Apr May Jun Jul Aug Sep Oct Nov

# of mandates

0

1

2

3

4

5

6

7

Mandate imposition timing

covid19.healthdata.org 8 Institute for Health Metrics and Evaluation

Page 11: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CRITICAL DRIVERS

Figure 8a. Trend in mobility as measured through smartphone app use compared to January 2020 baseline

−80

−60

−40

−20

0

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov

Per

cent

red

uctio

n fr

om a

vera

ge m

obili

ty

Republic of Korea Germany Italy United Kingdom United States of America

Figure 8b. Mobility level as measured through smartphone app use compared to January 2020 baseline(percent) on October 19, 2020

=<−50

−49 to −45

−44 to −40

−39 to −35

−34 to −30

−29 to −25

−24 to −20

−19 to −15

−14 to −10

>−10

covid19.healthdata.org 9 Institute for Health Metrics and Evaluation

Page 12: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CRITICAL DRIVERS

Figure 9a. Trend in the proportion of the population reporting always wearing a mask when leaving home

0

25

50

75

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov

Per

cent

of p

opul

atio

n

Republic of Korea Germany Italy United Kingdom United States of America

Figure 9b. Proportion of the population reporting always wearing a mask when leaving home on October19, 2020

<30%

30 to 34%

35 to 39%

40 to 44%

45 to 49%

50 to 54%

55 to 59%

60 to 64%

65 to 69%

>=70

covid19.healthdata.org 10 Institute for Health Metrics and Evaluation

Page 13: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CRITICAL DRIVERS

Figure 10a. Trend in COVID-19 diagnostic tests per 100,000 people

0

100

200

300

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov

Test

per

100

,000

pop

ulat

ion

Republic of Korea Germany Italy United Kingdom United States of America

Figure 10b. COVID-19 diagnostic tests per 100,000 people on October 14, 2020

<5

5 to 9.9

10 to 24.9

25 to 49

50 to 149

150 to 249

250 to 349

350 to 449

450 to 499

>=500

covid19.healthdata.org 11 Institute for Health Metrics and Evaluation

Page 14: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America CRITICAL DRIVERS

Figure 11. Increase in the risk of death due to pneumonia on February 1 compared to August 1

<−80%

−80 to −61%

−60 to −41%

−40 to −21%

−20 to −1%

0 to 19%

20 to 39%

40 to 59%

60 to 79%

>=80%

covid19.healthdata.org 12 Institute for Health Metrics and Evaluation

Page 15: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America PROJECTIONS AND SCENARIOS

Projections and scenarios

We produce three scenarios when projecting COVID-19. The reference scenario is our forecast of what wethink is most likely to happen. We assume that if the daily mortality rate from COVID-19 reaches 8 permillion, social distancing (SD) mandates will be re-imposed. The mandate easing scenario is what wouldhappen if governments continue to ease social distancing mandates with no re-imposition. The universal maskmandate scenario is what would happen if mask use increased immediately to 95% and social distancingmandates were re-imposed at 8 deaths per million.

Figure 12. Cumulative COVID-19 deaths until February 01, 2021 for three scenarios.

0

100,000

200,000

300,000

400,000

500,000

0

50

100

150

Feb Apr Jun Aug Oct Dec Feb

Cum

ulat

ive

deat

hsC

umulative deaths per 100,000

Continued SD mandate easing

Reference scenario

Universal mask use

Fig 13. Daily COVID-19 deaths until February 01, 2021 for three scenarios.

0

2,000

4,000

0.0

0.5

1.0

1.5

Feb Apr Jun Aug Oct Dec Feb

Dai

ly d

eath

sD

aily deaths per 100,000

Continued SD mandate easing

Reference scenario

Universal mask use

covid19.healthdata.org 13 Institute for Health Metrics and Evaluation

Page 16: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America PROJECTIONS AND SCENARIOS

Fig 14. Daily COVID-19 infections until February 01, 2021 for three scenarios.

0

200,000

400,000

600,000

0

50

100

150

200

Feb Apr Jun Aug Oct Dec Feb

Dai

ly in

fect

ions

Daily infections per 100,000

Continued SD mandate easing

Reference scenario

Universal mask use

covid19.healthdata.org 14 Institute for Health Metrics and Evaluation

Page 17: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America PROJECTIONS AND SCENARIOS

Fig 15. Month of assumed mandate re-implementation. (Month when daily death rate passes 8 per million,when reference scenario model assumes mandates will be re-imposed.)

October

November

December

JanuaryNo mandates before Feb 1

covid19.healthdata.org 15 Institute for Health Metrics and Evaluation

Page 18: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America PROJECTIONS AND SCENARIOS

Figure 16. Forecasted percent infected with COVID-19 on February 01, 2021

<1

1−3.9

4−6.9

7−10.4

10.5−13.4

13.5−16.4

16.5−19.4

19.5−22.4

22.5−25.4

>=25.5

Figure 17. Daily COVID-19 deaths per million forecasted on February 01, 2021 in the reference scenario

<1

1 to 1.9

2 to 2.9

3 to 3.9

4 to 4.9

5 to 5.9

6 to 6.9

7 to 7.9

>=8

covid19.healthdata.org 16 Institute for Health Metrics and Evaluation

Page 19: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America PROJECTIONS AND SCENARIOS

Figure 18. Comparison of reference model projections with other COVID modeling groups. For thiscomparison, we are including projections of daily COVID-19 deaths from other modeling groups when avail-able: Delphi from the Massachussets Institute of Technology (Delphi; https://www.covidanalytics.io/home),Imperial College London (Imperial; https://www.covidsim.org), The Los Alamos National Laboratory(LANL; https://covid-19.bsvgateway.org/), the SI-KJalpha model from the University of Southern Cal-ifornia (SIKJalpha; https://github.com/scc-usc/ReCOVER-COVID-19), and Youyang Gu (YYG; https://covid19-projections.com/). Daily deaths from other modeling groups are smoothed to remove inconsistencieswith rounding. Regional values are aggregates from availble locations in that region.

500

1,000

1,500

2,000

Nov Dec Jan FebDate

Dai

ly d

eath

s

Models

IHME

Delphi

Imperial

LANL

SIKJalpha

YYG

covid19.healthdata.org 17 Institute for Health Metrics and Evaluation

Page 20: Current situation Trends in key drivers of transmission (mobility, … · 2020. 10. 22. · United States Model updates for October 22, 2020 covid.healthdata.org Institute for Health

United States of America PROJECTIONS AND SCENARIOS

Table 3. Ranking of COVID-19 among the leading causes of mortality in the full year 2020. Deaths fromCOVID-19 are projections of cumulative deaths on Jan 1, 2021 from the reference scenario. Deaths fromother causes are from the Global Burden of Disease study 2019 (rounded to the nearest 100).

Cause name Annual deaths RankingIschemic heart disease 557,600 1COVID-19 318,735 2Tracheal, bronchus, and lung cancer 206,200 3Chronic obstructive pulmonary disease 195,800 4Stroke 189,500 5Alzheimer’s disease and other dementias 143,900 6Chronic kidney disease 107,000 7Colon and rectum cancer 84,000 8Lower respiratory infections 81,900 9Diabetes mellitus 77,700 10

Mask data source: Premise; Facebook Global symptom survey (This research is based on survey resultsfrom University of Maryland Social Data Science Center) and the Facebook United States symptom survey(in collaboration with Carnegie Mellon University); Kaiser Family Foundation; YouGov COVID-19 BehaviourTracker survey.

A note of thanks:

We would like to extend a special thanks to the Pan American Health Organization (PAHO) for keydata sources; our partners and collaborators in Argentina, Brazil, Bolivia, Chile, Colombia, Cuba, theDominican Republic, Ecuador, Egypt, Honduras, Israel, Japan, Malaysia, Mexico, Moldova, Panama, Peru,the Philippines, Russia, Serbia, South Korea, Turkey, and Ukraine for their support and expert advice; andto the tireless data collection and collation efforts of individuals and institutions throughout the world.

In addition, we wish to express our gratitude for efforts to collect social distancing policy information inLatin America to University of Miami Institute for Advanced Study of the Americas (Felicia Knaul, MichaelTouchton), with data published here: http://observcovid.miami.edu/; Fundación Mexicana para la Salud(Héctor Arreola-Ornelas) with support from the GDS Services International: Tómatelo a Pecho A.C.; andCentro de Investigaciones en Ciencias de la Salud, Universidad Anáhuac (Héctor Arreola-Ornelas); Lab onResearch, Ethics, Aging and Community-Health at Tufts University (REACH Lab) and the University ofMiami Institute for Advanced Study of the Americas (Thalia Porteny).

Further, IHME is grateful to the Microsoft AI for Health program for their support in hosting our COVID-19data visualizations on the Azure Cloud. We would like to also extend a warm thank you to the many otherswho have made our COVID-19 estimation efforts possible.

covid19.healthdata.org 18 Institute for Health Metrics and Evaluation


Recommended