2021Curriculum Catalogfor MedicineDelivering solutions to support
your program goals
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Trusted names like Nelson, Swartz,
and Ferri
Student Self-Assessment
Clinical Key Student
Trusted names like Rapid Review, Crush,
and the Secrets Series
Board-Style Questions
Clinical Key Student
Trusted names like Netter, Gray’s,and Robbins
Student Self-Assessment
Clinical Key Student
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Medicine Curriculum Solution
Trusted names likeRosen, Harriet Lane,and Goldman-Cecil
ClinicalKey
RADPrimer
PATHPrimer
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Anatomy..............................10
Biochemistry.......................10
Cardiology...........................11
Embryology.........................11
Epidemiology......................11
Histology.............................11
Immunology.......................12
Internal Medicine...............12
Microbiology.......................12
Cardiology...........................14
Dermatology........................15
Emergency Medicine..........15
Health System Science........15
Infectious Disease...............15
Internal Medicine................15
Medical Ethics.....................16
Medical Spanish..................16
Neurology...........................16
OB/GYN..............................16
Ferri’s Clinical Advisor 2022
ISBN: 9780323755702
See ad on page 7
Robbins and Cotran Review of Pathology, 5th Edition
ISBN: 9780323640220
See ad on page 7
Robbins and Cotran Atlas of Pathology, 4th Edition
ISBN: 9780323640183
See ad on page 8
Medical Microbiology9th Edition
ISBN: 9780323673228
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Guyton and Hall Textbook of Medical Physiology14th Edition
ISBN: 9780323597128
See ad on page 9
Guyton & Hall Physiology Review, 4th Edition
ISBN: 9780323639996
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CLERKSHIP
PRE-CLINICALNeuroanatomy....................12
Neurology...........................12
Neuroscience......................12
Pathology.............................13
Pediatrics.............................13
Pharmacology.....................13
Physiology...........................14
Primary Care......................14
Urology...............................14
Pediatrics.............................16
Physical Diagnosis...............17
Psychiatry.............................17
Pulmonary Medicine...........17
Radiology.............................17
Surgery.................................17
Test......................................18
Ultrasound...........................18
USMLE Prep........................18
Featured Medicine Titles
Unparalleled, world-renowned, clinically relevant anatomic illustration
Netter Atlas of Human Anatomy, 8th Edition
March 2022 | ISBN: 9780323680424
Author: Frank H. Netter, MD
For students and clinical professionals who are learning anatomy,
participating in a dissection lab, sharing anatomy knowledge with patients,
or refreshing their anatomy knowledge, the Netter Atlas of Human
Anatomy illustrates the body, region by region, in clear, brilliant detail
from a clinician’s perspective. Unique among anatomy atlases, it contains
illustrations that emphasize anatomic relationships that are most important
to the clinician in training and practice. Illustrated by clinicians, for
clinicians, it contains more than 550 exquisite plates plus dozens of carefully
selected radiologic images for common views.
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Netter’s Anatomy Flash Cards, 6th Edition
March 2022 | ISBN: 9780323834179
Author: John T. Hansen, PhD
Learn, review, and self-test with these bestselling flash cards! Fun, fast,
and in full color, Netter’s Anatomy Flash Cards are a portable study tool for
a solid foundation in the anatomy you need to know for coursework and
exams. Each card presents art by Dr. Frank H. Netter (with several paintings
by Dr. Carlos Machado), numbered labels with hidden answers for self-
quizzing, and concise comments and clinical notes.
J O H N T . H A N S E N
NE T T E R ’ S
ANATOMY FLASH CARDS
6T H E D I T I O N
Gray’s Atlas of Anatomy, 3rd Edition2020 | ISBN: 9780323636391
• Build on your existing anatomy knowledge with
structures presented from a superficial to deep
orientation, representing a logical progression
through the body.
• Identify the various anatomical structures of the
body and better understand their relationships
to each other with the visual guidance of nearly
1,000 exquisitely illustrated anatomical figures.
• Visualize the clinical correlation between
anatomical structures and surface landmarks
with surface anatomy photographs overlaid with
anatomical drawings.
Gray’s Anatomy Review, 3rd Edition2021 | ISBN: 9780323639163
• Includes more than 1,400 high-yield questions,
mirroring the USMLE Step 1 and complete with
answers and rationales that challenge your grasp
of anatomical knowledge and the anatomical basis
of disease.
• Features a new neuroanatomy chapter
containing approximately 100 all-new questions
that cover key concepts and relate them to clinical
practice.
• Groups questions more logically within
chapters for more effective study, first within
topic areas and then from easy to more difficult.
Gray’s Anatomy for Students, 4th Edition2019 | ISBN: 9780323393041
• Helps students understand the practical applications of
anatomical concepts through unique coverage of surface
anatomy, correlative diagnostic images, and clinical case
studies.
• Presents anatomy logically by body region, and now
offers bonus eBook chapters for each major body system
to facilitate learning from a different perspective –
covering the Cardiovascular System, Respiratory System,
Gastrointestinal System, Urogenital System, Lymphatic
System, and Nervous System.
• Features an all-new eBook chapter covering the essentials
of neuroanatomy so that readers can learn key aspects of
this challenging topic in the context of general anatomy.
Gray’s Anatomy for Students Flash Cards, 4th Edition2019 | ISBN: 9780323639170
• Study efficiently while being confident in your
mastery of the most important anatomical concepts!
Flashcards have been thoroughly revised to reflect the
updates made to the companion text, Gray’s Anatomy
for Students, 4th Edition.
• Understand the clinical relevance of your anatomical
knowledge with clinical imaging cards.
• Conveniently access all of the need-to-know anatomy
information! Each card presents beautiful 4-color
artwork or a radiologic image of a particular structure/
area of the body, with numbered leader lines indicating
anatomical structures; labels to the structures are
listed by number on the reverse, in addition to relevant
functions, clinical correlations, and more.
Contact your Elsevier Education Solutions Consultant | 6
2021 | ISBN: 9780323755702
Also available as an ebook
Find fast answers to inform your daily diagnosis and treatment decisions
• Contains significant updates throughout, covering all aspects of current
diagnosis and treatment.
• Features 30 all-new topics including COVID-19 disease, anal cancer,
electronic cigarette or vaping–associated lung injury (EVALI), gaming disorder,
early pregnancy loss, smoke inhalation injury, and subjective cognitive decline,
among others.
• Includes useful appendices covering common herbs in integrated medicine
and herbal activities against pain and chronic diseases; care of the transgender
patient, palliative care; preoperative evaluation, and more.
• Offers online access to Patient Teaching Guides in both English and Spanish.
2021 | ISBN: 9780323640220
Also available as an ebook
The most effective and efficient review of pathology, from the names you trust
• Contains 1,500 vignette-style questions in print that reinforce clinical applications
and incorporate key patient care and diagnostic strategies (history, physical
examination, laboratory testing, and radiologic imaging). Online, 500 additional
interactive questions cover more challenging topics and less common conditions.
• Uses single-best-answer and extended-matching formats to reflect levels of
difficulty that prepare you for examinations. Questions are written in the style of
USMLE and MCCQE questions that you will encounter for qualifying examinations.
• Covers the fundamentals of gross and microscopic pathology, as well as the latest
findings in molecular biology and genetics. Answers and detailed explanations for
every question are found at the end of each chapter.
• Incorporates recent changes in the understanding of the pathophysiology
underlying disease processes, as well as the approach to workup and diagnosis of
disease conditions.
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2020 | ISBN: 9780323640183
Also available as an ebook
Outstanding visual support from the name
you trust in pathology
• Quickly compare gross, microscopic, and radiologic images with examples of
normal organs and tissues.
• Review just the key information you need to know with help from extensive
legends that provide convenient summaries and highlight key aspects of patient
care and diagnostic strategies.
• Understand the correlation between pathology and clinical history, physical exam
findings, and clinical laboratory tests.
• Visualize key pathologic findings with crystal clarity through over 100 new or
updated images.
• Access the complete, fully searchable text plus BONUS e-only figures via the
accompanying downloadable eBook.
2020 | ISBN: 9780323673228
Also available as an ebook
Master the essentials of microbiology with the leading text in the field
• Features significant new information on the human microbiome and its influence
on the immune and other body systems, and new developments in microbial
diagnosis, treatment, diseases, and pathogens.
• Updates every chapter with state-of-the-art information and current literature
citations.
• Summarizes detailed information in tabular format rather than in lengthy text.
• Provides review questions at the end of each chapter that correlates basic science
with clinical practice.
• Features clinical cases that illustrate the epidemiology, diagnosis, and treatment
of infectious diseases.
• Introduces microbe chapters with summaries and trigger words for easy review.
• Highlights the text with clear, colorful figures, clinical photographs, and images
that help you visualize the clinical presentation of infections.
Contact your Elsevier Education Solutions Consultant | 8
2020 | ISBN: 9780323597128
Also available as an ebook
A simple approach to complex concepts from
the world’s foremost physiology textbook
• Offers a clinically oriented perspective written with the clinical and preclinical
student in mind, bridging basic physiology with pathophysiology.
• Focuses on core material and how the body maintains homeostasis to remain
healthy, emphasizing the important principles that will aid in later clinical
decision-making.
• Presents information in short chapters using a concise, readable voice that
facilitates learning and retention.
• Contains more than 1,200 full-color drawings and diagrams – all carefully
crafted to make physiology easier to understand.
• Features expanded clinical coverage, including obesity, metabolic and
cardiovascular disorders, Alzheimer’s disease, and other degenerative diseases.
• Includes online access to interactive figures, new audio of heart sounds,
animations, self-assessment questions, and more.
2021 | ISBN: 9780323639996
Also available as an ebook
Maximize your study time and ace your exams
• Cross-referenced to the bestselling Guyton and Hall Textbook of Medical
Physiology, 14th Edition, highlighting essential key concepts and featuring direct
page references to specific questions.
• Thorough reviews of all major body systems, with an emphasis on system
interaction, homeostasis, and pathophysiology.
• More than 1,000 board-style questions and answers on the most essential, need-
to-know concepts prepare you for your exams, including the physiology portion of
the USMLE Step 1.
• eBook includes an interactive quiz mode for self-assessment and exam practice.
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Contact your Elsevier Education Solutions Consultant | 10
Gosling Human Anatomy, Color Atlas and Textbook,6th Edition
2016
ISBN: 9780723438274
Drake Gray’s Basic Anatomy,2nd Edition
2017
ISBN: 9780323474047
Smith Gray’s Surface Anatomy and Ultrasound
2017
ISBN: 9780702070181
Hansen Netter’s Clinical Anatomy,4th Edition
2018
ISBN: 9780323531887
Hansen Netter’s Anatomy Flash Cards, 5th Edition
2018
ISBN: 9780323530507
Netter Atlas of Human Anatomy,7th Edition
2018
ISBN: 9780323393225
Loukas Gray’s Clinical Photographic Dissector of the Human Body,2nd Edition
2018
ISBN: 9780323544177
DrakeGray’s Anatomy forStudents, 4th Edition
2019
ISBN: 9780323393041
Abrahams Abrahams’ and McMinn’s Clinical Atlas of Human Anatomy,8th Edition
2019
ISBN: 9780702073328
Drake Gray’s Anatomy for Students Flash Cards,4th Edition
2019
ISBN: 9780323639170
Drake Gray’s Atlas of Anatomy,3rd Edition
2020
ISBN: 9780323636391
Spratt Weir & Abrahams’ Imaging Atlas of Human Anatomy,6th Edition
2020
ISBN: 9780702079269
Loukas Gray’s Anatomy Review,3rd Edition
2021
ISBN: 9780323639163
Meisenberg Principles of Medical Biochemistry, 4th Edition
2016
ISBN: 9780323296168
Hansen Netter’s Anatomy Coloring Book,3rd Edition
2021
ISBN: 9780323826730
ANATOMY
BIOCHEMISTRY
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BIOCHEMISTRY CONTINUED
Ronner Netter’s Essential Biochemistry
2017
ISBN: 9781929007639
BaynesMedical Biochemistry,5th Edition
2018
ISBN: 9780702072994
NaqviPoint-of-Care Echocardiography
2021
ISBN: 9780323612845
CarlsonHuman Embryology and Developmental Biology,6th Edition
2018
ISBN: 9780323523752
MooreThe Developing Human,11th Edition
2019
ISBN: 9780323611541
MooreBefore We Are Born,10th Edition
2019
ISBN: 9780323608497
SchoenwolfLarsen’s Human Embryology, 6th Edition
2021
ISBN: 9780323696043
NussbaumThompson & Thompson Genetics in Medicine,8th Edition
2015
ISBN: 9781437706963
CARDIOLOGY
EPIDEMIOLOGY
HISTOLOGY
Celentano Gordis Epidemiology,6th Edition
2018
ISBN: 9780323552295
Elmore Jekel’s Epidemiology, Biostatistics, Preventive Medicine, and Public Health, 5th Edition
2020
ISBN: 9780323642019
Jorde Medical Genetics,6th Edition
2019
ISBN: 9780323597371
Turnpenny Emery’s Elements of Medical Genetics,16th Edition
2021
ISBN: 9780702079665
LoweStevens & Lowe’s Human Histology, 5th Edition
2019
ISBN: 9780323612791
KierszenbaumHistology and Cell Biology: An Introduction to Pathology, 5th Edition
2019
ISBN: 9780323673211
GartnerTextbook of Histology,5th Edition
2020
ISBN: 9780323672726
EMBRYOLOGY
Contact your Elsevier Education Solutions Consultant | 12
OvalleNetter’s Essential Histology, 3rd Edition
2020
ISBN: 9780323694643
YoungWheater’s Functional Histology, 6th Edition
2013
ISBN: 9780702047473
HelbertImmunology for Medical Students,3rd Edition
2016
ISBN: 9780702068010
AbbasBasic Immunology,6th Edition
2019
ISBN: 9780323549431
AbbasCellular and Molecular Immunology, 10th Edition
2021
ISBN: 9780323757485
KellermanConn’s Current Therapy 2022
2021
ISBN: 9780323833783
GoeringMims’ Medical Microbiology and Immunology,6th Edition
2018
ISBN: 9780702071546
KlossGraphic Guide to Infectious Disease
2018
ISBN: 9780323442145
Murray Medical Microbiology,9th Edition
2020
ISBN: 9780323673228
RubinNetter’s Concise Neuroanatomy Updated Edition
2016
ISBN: 9780323480918
MendezThe Mental Status Examination Handbook
2021
ISBN: 9780323694896
FeltenNetter’s Neuroscience Flash Cards, 3rd Edition
2015
ISBN: 9780323401562
HainesFundamental Neuroscience for Basic and Clinical Applications, 5th Edition
2017
ISBN: 9780323396325
VanderahNolte’s Essentials of the Human Brain,2nd Edition
2018
ISBN: 9780323529310
HISTOLOGY CONTINUED
IMMUNOLOGY
Murray Basic Medical Microbiology
2017
ISBN: 9780323476768
IMMUNOLOGY
INTERNAL MEDICINE
MICROBIOLOGY
NEUROANATOMY NEUROLOGY
NEUROSCIENCE
VanderahNolte’s The Human Brain, 8th Edition
2020
ISBN: 9780323653985
MtuiFitzgerald’s Clinical Neuroanatomy and Neuroscience,8th Edition
2020
ISBN: 9780702079092
FeltenNetter’s Atlas of Neuroscience,4th Edition
2021
ISBN: 9780323756549
KlattRobbins and Cotran Pathology Flash Cards,2nd Edition
2015
ISBN: 9780323352222
KumarRobbins Basic Pathology,10th Edition
2017
ISBN: 9780323353175
PATHOLOGY
Goljan Rapid Review Pathology,5th Edition
2018
ISBN: 9780323476683
KumarRobbins & Cotran Pathologic Basis of Disease,10th Edition
2020
ISBN: 9780323531139
KumarRobbins Essential Pathology
2020
ISBN: 9780323640251
KlattRobbins and Cotran Atlas of Pathology,4th Edition
2020
ISBN: 9780323640183
KlattRobbins and Cotran Review of Pathology,5th Edition
2021
ISBN: 9780323640220
ZitelliZitelli and Davis’ Atlas of Pediatric Physical Diagnosis, 8th Edition
2021
ISBN: 9780323777889
BrennerPharmacology Flash Cards, 4th Edition
2017
ISBN: 9780323355643
StevensBrenner and Stevens’ Pharmacology,5th Edition
2017
ISBN: 9780323391665
WeckerBrody’s Human Pharmacology,6th Edition
2018
ISBN: 9780323476522
RitterRang & Dale’sPharmacology,9th Edition
2019
ISBN: 9780702074486
PEDIATRICS
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NEUROSCIENCE CONTINUED
PHARMACOLOGY
Contact your Elsevier Education Solutions Consultant | 14
MulroneyNetter’s Essential Physiology, 2nd Edition
2015
ISBN: 9780323358194
MulroneyNetter’s Physiology Flash Cards, 2nd Edition
2015
ISBN: 9780323359542
BoronMedical Physiology,3rd Edition
2016
ISBN: 9781455743773
KoeppenBerne & Levy Physiology,7th Edition
2017
ISBN: 9780323393942
HallGuyton and Hall Textbook of Medical Physiology,14th Edition
2020
ISBN: 9780323597128
HallGuyton & Hall Physiology Review, 4th Edition
2020
ISBN: 9780323639996
HallPocket Companion to Guyton and Hall Textbook of Medical Physiology, 14th Edition
2020
ISBN: 9780323640077
BoronBoron & Boulpaep Concise Medical Physiology
2020
ISBN: 9780323655309
FerriFerri’s Clinical Advisor 2022
2021
ISBN: 9780323755702
PartinCampbell Walsh Wein Handbook of Urology
2021
ISBN: 9780323827478
American Society of EchocardiographyASE’s Comprehensive Echocardiography,3rd Edition
2021
ISBN: 9780323698306
LevineCardiology Secrets,5th Edition
2017
ISBN: 9780323478700
StoufferNetter’s Cardiology,3rd Edition
2018
ISBN: 9780323547260
CostanzoPhysiology, 7th Edition
2021
ISBN: 9780323793339
PHYSIOLOGY
PRIMARY CARE UROLOGY
HamptonThe ECG Made Practical,7th Edition
2019
ISBN: 9780702074608
CARDIOLOGY
HamptonThe ECG Made Easy,9th Edition
2019
ISBN: 9780702074578
Hampton150 ECG Cases,5th Edition
2019
ISBN: 9780702074585
HabifSkin Disease, 4th Edition
2017
ISBN: 9780323442220
FerriFerri’s Fast Facts in Dermatology,2nd Edition
2017
ISBN: 9780323530392
DERMATOLOGY
EMERGENCY MEDICINE
MarksLookingbill and Marks’ Principles of Dermatology,6th Edition
2018
ISBN: 9780323430401
DinulosHabif’s Clinical Dermatology,7th Edition
2020
ISBN: 9780323612692
BologniaDermatology Essentials,2nd Edition
2021
ISBN: 9780323624534
RobertsRoberts and Hedges’ Clinical Procedures in Emergency Medicine and Acute Care,7th Edition
2018
ISBN: 9780323354783
MarkovchickEmergency Medicine Secrets, 7th Edition
2021
ISBN: 9780323694735
EhrenfeldHealth Systems Science Review
2019
ISBN: 9780323653701
SkochelakHealth Systems Science,2nd Edition
2020
ISBN: 9780323694629
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TemesgenA Rational Approach to Clinical Infectious Diseases
2021
ISBN: 9780323695787
O’ConnellInstant Work-ups: A Clinical Guide to Medicine,2nd Edition
2016
ISBN: 9780323376419
LoukasNetter’s Introduction to Clinical Procedures
2016
ISBN: 9780323370554
MarshallOn Call Principles and Protocols, 6th Edition
2016
ISBN: 9780323479769
CARDIOLOGY CONTINUED
HEALTH SYSTEM SCIENCE INFECTIOUS DISEASE
INTERNAL MEDICINE
ALL CLERKSHIP RESOURCES
Contact your Elsevier Education Solutions Consultant | 16
SymonsDifferential Diagnosis of Common Complaints,7th Edition
2017
ISBN: 9780323512329
MEDICAL ETHICS
RosenbergNetter’s Clinical Skills
2018
ISBN: 9780323551649
StrausEvidence-Based Medicine,5th Edition
2018
ISBN: 9780702062964
WuGunner Goggles Medicine
2018
ISBN: 9780323510356
BenjaminAndreoli and Carpenter’s Cecil Essentials of Medicine,10th Edition
2021
ISBN: 9780323722711
ChambersField Guide to Global Health & Disaster Medicine
2021
ISBN: 9780323794121
WilkinsonMedical Ethics and Law,3rd Edition
2019
ISBN: 9780702075964
OrtegaSpanish and the Medical Interview: Clinical Cases and Exam Review
2021
ISBN: 9780323756488
MisulisNetter’s Concise Neurology Updated Edition
2016
ISBN: 9780323482547
FullerNeurological Examination Made Easy, 6th Edition
2019
ISBN: 9780702076275
INTERNAL MEDICINE CONTINUED
HISTOLOGY
HughesA Medication Guide to Internal Medicine Tests and Procedures
2021
ISBN: 9780323790079
MayerOn Call Neurology,4th Edition
2020
ISBN: 9780323546942
HackerHacker & Moore’s Essentials of Obstetrics and Gynecology,6th Edition
2015
ISBN: 9781455775583
SmithNetter’s Obstetrics and Gynecology,3rd Edition
2017
ISBN: 9780702070365
MEDICAL SPANISH
NEUROLOGY
OB/GYN
MarcdanteNelson Essentials of Pediatrics, 8th Edition
2018
ISBN: 9780323511452
PEDIATRICS
ALL CLERKSHIP RESOURCES
NoctonOn Call Pediatrics,4th Edition
2018
ISBN: 9780323529051
NEUROANATOMY
The Johns Hopkins HospitalThe Harriet Lane Handbook,22nd Edition
2020
ISBN: 9780323674072
The Hospital for Sick ChildrenThe Hospital for Sick Children Handbook of Pediatrics, 12th Edition
2021
ISBN: 9780323713405
ColeThe Medical Interview,3rd Edition
2013
ISBN: 9780323052214
SwartzTextbook of Physical Diagnosis, 8th Edition
2020
ISBN: 9780323672924
ClelandNetter’s Orthopaedic Clinical Examination,4th Edition
2021
ISBN: 9780323695336
McGeeEvidence-Based Physical Diagnosis, 5th Edition
2021
ISBN: 9780323754835
SheaPsychiatric Interviewing,3rd Edition
2016
ISBN: 9781437716986
BernsteinOn Call Psychiatry,4th Edition
2018
ISBN: 9780323531092
WeinbergerPrinciples of Pulmonary Medicine,7th Edition
2018
ISBN: 9780323523714
MettlerEssentials of Radiology,4th Edition
2018
ISBN: 9780323508872
PEDIATRICS CONTINUED
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HerringLearning Radiology,4th Edition
2019
ISBN: 9780323567299
ShafaLearning Interventional Radiology
2019
ISBN: 9780323478793
The University of Cincinnati ResidentsThe Mont Reid Surgical Handbook, 7th Edition
2017
ISBN: 9780323529808
HartmanHandbook of Surgical Technique
2017
ISBN: 9780323462013
PHYSICAL DIAGNOSIS
PSYCHIATRY
PULMONARY MEDICINE RADIOLOGY
SURGERY
ALL CLERKSHIP RESOURCES
Contact your Elsevier Education Solutions Consultant | 18
AdamsOn Call Surgery,4th Edition
2019
ISBN: 9780323528894
FerriFerri’s Best Test,4th Edition
2017
ISBN: 9780323511407
SoniPoint of Care Ultrasound,2nd Edition
2019
ISBN: 9780323544702
O’ConnellUSMLE Step 3 Secrets
2014
ISBN: 9781455753994
SURGERY CONTINUED
IMMUNOLOGY
ULTRASOUND
O’ConnellUSMLE Step 2 Secrets,5th Edition
2017
ISBN: 9780323496162
SalazarPediatrics Morning Report
2018
ISBN: 9780323498258
DasguptaMedicine Morning Report: Beyond Pearls
2016
ISBN: 9780323358095
BrownUSMLE Step 1 Secrets in Color, 4th Edition
2016
ISBN: 9780323396790
O’ConnellCrush Step 1,2nd Edition
2017
ISBN: 9780323481632
MeriwetherObstetrics & Gynecology Morning Report
2018
ISBN: 9780323496131
WilliamsSurgery Morning Report: Beyond the Pearls
2019
ISBN: 9780323597593
DuongPsychiatry Morning Report: Beyond the Pearls
2020
ISBN: 9780323672962
BhanotePathology Case Reports
2020
ISBN: 9780323754897
TEST
USMLE PREP
ALL CLERKSHIP RESOURCES
CONTACTyour Elsevier Education Solutions Consultant
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2021Curriculum Catalogfor MedicineDelivering solutions to support
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2021Curriculum Catalog for Medicine