CURRICULUM VITAE NAME: Ayman Al-Hendy, M.D., Ph.D., FRCSC, FACOG, CCRP August, 2018 PRESENT POSITION AND ADDRESS: Professor & Director Translational Research Department of Obstetrics and Gynecology College of Medicine University of Illinois/Chicago (UIC) Gynecologist UIC Health UIC Medical Center CSN-W204 (Clinical) COMRB-7100 (Research) 820 South Wood Street Chicago, IL 60612 Tel. 312-355-1385 (work) Tel. 713-201-9644 (cell) Fax. 312-966-4238 [email protected]Skype: aalhendy BIOGRAPHICAL: Date of Birth: January 24, 1964 Citizenship: Egypt/Canada/USA Marital Status: Married, 2 Children PROFESSIONAL AND TEACHING EXPERIENCE: 1
Date of Birth: January 24, 1964Citizenship: Egypt/Canada/USAMarital Status: Married, 2 Children
PROFESSIONAL AND TEACHING EXPERIENCE:
01/2018-Present Professor (Tenured) & Director, Translational Research, Department of Obstetrics and Gynecology, College of Medicine, University of Illinois/Chicago (UIC), Chicago, Illinois
01/2018- Present Gynecologist, University of Illinois Medical Practice Group, Chicago, Illinois
02/14 – 01/2018 Professor (Tenured) & Director, Division of Translational Research, Department of Obstetrics and Gynecology, Medical
College of Georgia, Augusta University (formerly Georgia Regents University), Augusta, Georgia
02/14 – 01/2018 Assistant Dean for Global Translational Research, Medical College of Georgia, Augusta University (formerly Georgia Regents University), Augusta, Georgia
02/14 – 01/2018 Director of Interdisciplinary Translational Research, Augusta University (formerly Georgia Regents University), Augusta, Georgia
02/14- 01/2018 Gynecologist/Obstetrician, Augusta University Medical Practice Group, Augusta, Georgia
09/07 – 02/14 Professor (Tenure) & Vice Chair, Department of Obstetrics and Gynecology, Meharry Medical College, Nashville, Tennessee
09/07 – 02/14 Scientific Director, Center for Women Health Research, Meharry Medical College, Nashville, Tennessee
09/07- 02/14 Gynecologist/Obstetrician, Nashville (Metro) General Hospital, Nashville, Tennessee
12/07 – 02/14 Adjunct Professor, Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee
09/09 – 03/10 Co-Director, Meharry Translational & Clinical Research Center (MeTRC), Meharry Medical College, Nashville, Tennessee
12/07 – 12/08 Associate Director, Clinical Research Center, Meharry Medical College, Nashville, Tennessee
09/06 – 09/07 Associate Professor, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
08/00 – 08/06 Assistant Professor, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas
07/00 – 08/00 Obstetrician and Gynecologist (Locum)Swift Current Health District, Saskatchewan, Canada
07/95 – 06/00 Residents and Medical Student Teaching and SupervisionGrand Rounds, Residents Academic Teaching, Department of Obstetrics and Gynecology, Saskatoon, Saskatchewan, Canada
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11/88 – 04/92 Teaching Assistant, Department of Medical MicrobiologyTurku University, Turku, Finland
EDUCATION:
07/95 – 06/00 ResidentDepartment of Obstetrics and GynecologyRoyal University HospitalUniversity of SaskatchewanSaskatchewan, Canada
07/94 – 06/95 FellowCanadian College of Medical GeneticsSpecialty: Clinical Molecular GeneticsMedical Genetics UnitMcGill UniversityMontréal Children’s Hospital Research InstituteMontréal, Québec, Canada
06/92 – 06/94 Post Doctoral Research FellowDivision of Human GeneticsDepartment of PediatricsMcMaster UniversityHamilton, Ontario, Canada
11/88 – 06/92 Ph.D. Graduate StudentDNA - LaboratoryDepartment of Medical MicrobiologyTurku UniversityTurku, Finland
03/88 – 11/88 ResidentDepartment of Oto-Rhino-LaryngologyBenha University HospitalBenha, Egypt
03/87 – 02/88 InternRotational InternshipBenha University HospitalBenha, Egypt
09/80 – 02/87 M.D.Benha Faculty of MedicineZagazig UniversityBenha, Egypt (General Grade: Excellent with Honor Degree, Ranked: First in graduating class)
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10/77 – 06/80 General Secondary School Certificate (G.S.S.C)Benha, Egypt
BOARD CERTIFICATIONS:
12/11 Certified Clinical Research Professional (CCRP), AMERICAN SOCIETY OF CLINICAL RESEARCH ASSOCIATES (SOCRA)
11/11 Certified Physician Executive (CPE) Program, American College of Physician Executives (ACPE). (Approved CME hours completed, awaiting final certification, Complete Certification anticipated in 2018)
09/03 FellowAmerican College of Obstetricians and Gynecologists (ACOG)
11/02 Certified/Recertified DiplomatAmerican Board of Obstetrics and Gynecology (ABOG)
07/00 Fellow Society of Obstetricians and Gynecologists of Canada (SOGC)
6/00 FellowRoyal College of Physicians and Surgeons of Canada (Obstetrics and Gynecology)
LICENSURE INFORMATION:
State of IllinoisIllinois Department of Financial and Professional RegulationExpiration: 7/31/2020
State of GeorgiaGeorgia Composite Medical BoardExpiration: 1/31/2019
Controlled Substance RegistrationUnited States Department of JusticeDrug Enforcement AdministrationExpiration: 6/30/18
Prior Medical licenses TexasFloridaTennesseePennsylvania
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Saskatchewan (Canada) Ontario (Canada) Egypt
Educational Commission for Foreign Medical GraduatesCertificate Number 0-588-060-4Validation: Indefinitely4/1999
United States Medical Licensing Examination, Step 3ID: 0-588-060-412/1999
Licentiate of the Medical Council of Canada Number 806571/97
CURRENT CLINICAL/ACADEMIC INTEREST:
1. An avid interest in improving the health care of women, and eliminate health disparity.
2. Gynecologic endoscopy (laparoscopy and hysteroscopy).3. Clinical, translational, and basic research in Gynecology.4. Uterine Fibroids Treatment and Research Center.5. Using molecular biological tools in research applications in Gynecology and
Obstetrics especially in the area of “reproductive genetics, stem cell biology and gene/stem cell therapy”.
RESEARCH GRANTS:
A. ONGOING:
R01 ES 028615-01, Al-Hendy (PI)/Walker (co-PI) 09/15/2017-09/14/2022 Gene x Environment Interactions in the Pathogenesis of Uterine Fibroids Uterine Fibroids (UFs) are monoclonal tumors arising in the myometrium, and are the most common pelvic tumor of reproductive age women. An increasing body of evidence supports the hypothesis that UFs originate from aberrant stem cells in the myometrium. We have now identified a Stro-1+/CD44+ myometrial stem cell (MSCs) capable of self-renewal and regeneration of myometrial tissues that gives rise to fibroids in appropriate animal models. With our ability to identify and isolate these MSCs, we are in a unique position to address how risk factors for UFs impact stem cells to initiate and promote the development of these tumors. Like several other diseases, there is ample evidence that both environmental exposures and genetic alterations play key roles in the pathogenesis UFs. We, and others have shown that early life environmental exposures to endocrine disrupting compounds (EDCs) increase UF risk by inducing developmental reprogramming of the epigenome. Such epigenomic reprogramming involves changes in histone and DNA methylation patterns that alter chromatin architecture and gene transcription, which persist across the life course of the individual when induced in early life during sensitive period of myometrial development. Genetic alterations in mediator 12 (MED12) and the tuberous sclerosis complex 2 (TSC2) tumor suppressor, drive development of UF tumors in both humans and rodent models, respectively. Interestingly, MED12 and TSC2 defects share a common downstream effector: activation of β-catenin signaling and TCF/LEF transactivation of gene expression. As a field, the previous inability to interrogate the cells of origin for UF has
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limited our understanding of how gene and environmental interactions (GxE), influence UF risk. With our ability to isolate and profile MSCs, we are for the first time in a position to overcome this critical barrier to understanding determinants of risk for this important disease. In this application we will utilize our new-found ability to isolate and interrogate MSCs, and apply several recent insights on how environmental exposures reprogram the epigenome, to explore GxE interactions in the cells of origin for UFs.
R01HD087417-01A1 Boyer (PI) 08/01/2017-07/31/2022 NIH/NICHD Role: Co-InvestigatorMolecular basis of MED12 in the pathogenesis of uterine fibroids
R01 HD 094378-01 Boyer/Al-Hendy, MPIs 4/01/2018-3/30/2023Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroids Uterine fibroids (UFs; leiomyomas) are the most important benign neoplastic threat to women’s health worldwide, but disproportionately affect women of color, particularly African American (AA) women, who have a threefold higher incidence rate and relative risk of UFs than Caucasian (CC) women. While the underlying cause for this risk disparity is not fully understood, recent studies implicate hypovitaminosis D as a major contributor. Thus, AA women have a tenfold increased risk of vitamin D deficiency compared to CC women, and as we first reported, UF risk is inversely correlated with 25-hydroxy vitamin D serum levels. Nonetheless, it is not clear whether and how the processes that drive UF formation and determine relative risk are genetically or biochemically linked. In this regard, we and others have identified somatic mutations in the transcriptional Mediator subunit MED12 as the dominant drivers of UFs, accounting for ~70% of tumors. Notably, MED12-mutant UFs are characterized by significant chromosomal loss and rearrangement, suggesting genomic instability as a driving force in tumor progression. Herein, we clarify the molecular basis for mutant MED12-driven genomic instability, and further identify vitamin D3 receptor signaling as a likely suppressor of this process. We show that MED12-mutant UF stem cells (SCs) accumulate high levels of unrepaired DNA double strand breaks (DSBs) through downregulation of key DNA damage response (DDR) and repair genes. Notably, we find the vitamin D3/receptor axis to be a variable modulator of MED12-regulated DDR gene expression. Thus, we show that reduced vitamin D3/receptor signaling suppresses, while elevated signaling activates, DDR genes downregulated in MED12-mutant UF SCs. Based on these findings, we hypothesize that hypovitaminosis D exacerbates DNA damage accumulation and genomic instability arising in MED12-mutant UFs, leading to enhanced tumor progression and burden. Accordingly, we propose that vitamin D3, through reparation of an impaired DDR will provide therapeutic benefit in MED12-mutant tumors. To test thesehypotheses, we will (1) Elucidate the molecular basis of genomic instability in MED12-mutant UFs. We will determine if DSB accumulation in MED12-mutant UF SCs derives from defects in DNA damage-induced checkpoint signaling and repair and/or R-loop-induced replication stress. (2) Investigate the relationship between vitamin D3 and MED12 in UF genome maintenance. We will ask whether and how vitamin D3 signaling strength modulates the DDR defects in MED12-mutant UF SCs, relate this activity to patient race and serum vitamin D levels, and elucidate the mechanism by which the vitamin D3/receptor axis and MED12 coordinately control the DDR network at the genomic and epigenomic levels; (3) Examine the therapeutic potential of vitamin D3 in a preclinical mouse model of human UFs. Using a renal capsule mouse model of human UFs, we will evaluate vitamin D3 and its potent non-hypercalcemic analogs for therapeutic efficacy, safety, and mechanism of action, including impact on tumor DNA damage load and DDR gene networks.
R01 HD 094380-01 Borahay 08/01/2018-07/31/2023Al-Hendy Co-IMechanisms of actions(s) of simvastatin in uterine leiomyoma
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Uterine fibroids represent a significant medical challenge with an immense economic burden. With an estimated incidence of 70-80% in women by the age of 50 (1), they are the most common tumors of the female reproductive tract with an estimated annual costs in the US alone of $5.9-34.4 billion (2, 3). In clinical practice, hormonal therapies are used to address fibroid symptoms and may reduce fibroid size, but their effectiveness is limited and side effects reduce long-term use. Therefore, surgery is eventually required in many cases making fibroids the most common indication for hysterectomy in the US (4). From all this, it is clear that current pharmacologic treatments for fibroids are limited and unsatisfactory. Our team long-term goal is to develop novel non-surgical treatments for uterine fibroids. Simvastatin inhibits 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase enzyme, the rate limiting step of the mevalonate pathway that ends with cholesterol production. While commonly used for treating hyperlipidemia, simvastatin have profound cell type-specific effects, including certain anti-tumor properties (5-10). Our team recently discovered the following critical findings: 1) statin use is associated with a lower risk of uterine fibroids and fibroid-related symptoms in a population-based study (8); 2) simvastatin inhibits tumor growth in a patient-derived xenograft animal model (10); 3) simvastatin inhibits proliferation and induces apoptosis in human fibroid cells in vitro (9). Thus, it appears that simvastatin can be a promising anti-fibroid treatment. This leads to the natural next step of examining its clinical effects on uterine fibroids in vivo. The objective of this study is to examine simvastatin as a potential therapeutic for uterine fibroids in patients and examine the mechanisms of these effects, both in vivo and in vitro. Our central hypothesis is that simvastatin can provide beneficial clinical effects on uterine fibroids. We further hypothesize that these effects are mediated through inhibiting isoprenoids, intermediates of the mevalonate pathway necessary for Ras and Rho activation. This in turn modulates uterine fibroid stem cell biology and alters extracellular matrix (ECM) and mechanical homeostasis. To test this central hypothesis, we will execute the following specific aims : Aim 1. Characterize the clinical, cellular and molecular effects of simvastatin on uterine fibroids in vivo. We will administer simvastatin to patients with symptomatic uterine fibroid scheduled for surgery to assess symptoms and tumor size before and after treatment. We will examine tissues obtained during surgery to see the extent to which simvastatin inhibits proliferation; induces apoptosis; alters stem cell biology; and modulates ECM structure and mechanical signaling and homeostasis. Aim 2. Determine the molecular and cellular effects of simvastatin on uterine fibroid cells in vitro We will use 2-D and 3-D fibroid cell culture to: 2.A. Characterize the effects of simvastatin on fibroid stem cell biology and growth factor and steroid signaling pathways. We will also examine the role of Ras isoprenylation in these effects. 2.B. Examine the effects of simvastatin on uterine fibroid ECM production and structure; mechanical signaling and homeostasis. We will examine the role of Rho isoprenylation in these effects. The successful completion of this project can provide a leap forward toward discovering novel non-surgical, non-hormonal treatment of uterine fibroids. It will also provide insights on techniques of therapeutic modulation of critical fibroid pathways. This specifically addresses the mission and programmatic goals of the Gynecologic Health and Disease Branch (GHDB) as outlined in RFA-HD-18-017. Our research consortium is uniquely qualified as it integrates the necessary basic and clinical research expertise, resources, and infrastructure.
RCMI-G12 (Morehouse School of Medicine), Al-Hendy (PI, Project 1), 10/01/2018 - 09/30/2023
Project 1: Epigenomic Landscape of Reduced DNA Repair Capacity and Risk of UterineFibroids in African-AmericansUterine Fibroids are the most important benign neoplastic threat to women’s health, causing hundreds of billions of health care dollars worldwide. The overall goal of this proposal is to identify epigenetic mechanisms that promote the development of UFs in myometrium and corresponding MSCs, as well as to determine the effect of vitamin D3 on reversing disrupted epigenetic programming towards DNA repair pathway. The convergence of disciplines and expertise of our investigative team presents an exciting opportunity to advance our knowledge about how developmental adverse exposure and other risk factors impact the epigenome leading to DNA mutation and instability in MSCs.
Rose Study Al-Hendy (PI), MDStem cells Inc. 08/01/2018 – 31/07/2021Rejuvenation of Premature Ovarian Failure With Stem Cells (ROSE), https://clinicaltrials.gov/ct2/show/NCT02696889
CAPTURE-US/Allergan Inc. Al-Hendy (PI) 12/01/2016 – 11/30/2020Registry of Uterine Fibroids in the United States (RUFUS), Prospective, Non-Interventional/Observational Registry of US Uterine Fibroids Patients
M12-817 Al-Hendy (PI), AbbVie Inc. 01/01/2016-30/06/2018A phase 3 study to evaluate the efficacy of Elagolix in combination with Estradiol/Norethindrone acetate for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women
Asteroid-3 Al-Hendy (PI), Bayer Inc. 04/01/2017-30/06/2019A phase 3 study to evaluate the efficacy of Vilaprisan for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women
B. PENDING:
C. COMPLETED:
2R01HD046228-11 Al-Hendy (PI) 03/01/2010-08/28/2016 (NCE) NIH/NICHD Targeting Adenovirus for Uterine Leiomyoma Gene Therapy (Competitive Renewal to be submitted soon).
1K12 HD 085817-01 Diamond (PI) 07/01/15 - 06/30/20NIH/NICHDGRU Women’s Reproductive Health Research (WRHR) Career Development CenterThe overall objective of the Georgia Regents University (GRU) Women’s Reproductive Health Research (WRHR) proposed career development program is to develop independent OB/GYN physician-researchers in basic, translational and/or clinical areas related to women’s reproductive health.Role: Research Co-Director and Recruitment Director
Egyptian Academy of Science research agreement. Al-Hendy (PI) 06/01/2011-06/31/2016Developing adenoviral vectors for targeting vascular tissues
Watson Pharmaceuticals, NCT01553123 04/01/2012 – 03/30/2017Efficacy and Safety Study of Ulipristal Acetate in Females With Anemia Associated With Uterine Leiomyoma. Role: Al-Hendy, Site Principal Investigator
ZPU-309 Al-Hendy (PI), Repros Therapeutics Inc. 10/01/2014-09/30/2017A Phase III, open-label, Parallel, Randomized multicenter study evaluating the safety of 8, and 12 mg Proellex (CDB-4124) in the treatment of premenopausal women with symptomatic uterine fibroids.
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Merck Sharp & Dohme Corp., (Merck & Co.). NCT01448291 04/01/2012 – 03/30/2015A randomized, open-label, active-controlled, multicenter trial to assess the contraceptive efficacy and general safety of the oral commercial nomegestrol acetate (MK-9271/SCH900618/Org 10486-0) – 17ß estradiol (MK-8175/SCH900175/Org 2317) batch. Role: Al-Hendy, Site Principal Investigator
Abbott/Neuroscrine Biosciences, NCT01403038 09/01/2011 – 08/30/2014An Open-label Study of the Effects of Elagolix in Adult Premenopausal Females. Role: Al-Hendy, Site Principal Investigator
B1 58-3148-5-125 Al-Hendy (PI) USDA 09/30/2009–09/30/2014USDA/US-Egypt Joint Board on Scientific and Technological Cooperation Targeting Adenoviral Expression of Tissue-Type Plasminogen Activator Gene for Treatment of Postoperative Adhesions.
2R01HD046228-07-S2 Al-Hendy (PI) 10/01/2011-09/30/2012 Targeting Adenovirus for Uterine Leiomyoma Gene Therapy. Supplement to collaborate with an intramural research team @ NICHD to evaluate vitamin D in pathogenesis of uterine fibroids
Astra-Zeneca UK limited research agreement. Al-Hendy (PI) 02/01/2011-01/31/2013Evaluating AZ compounds in animal models of uterine fibroids
5G12RR003032-26, Riley (PI), NIH/NCRR 8/1/10-7/31/2015Meharry Research Center in Minority Institution Program (RCMI)Role on Program: Scientific Director
NIH/NCRR 3G12RR003032-25S1, Al-Hendy (PI) 09/30/2009 -08/30/2012T1/T2 translational supplements, “Green Tea extract: a non-surgical alternative for treatment of uterine fibroids”. www.Clinicaltrial.gov identifier No. NCT01311869.
2R01HD046228-07-S1 Al-Hendy (PI) 03/01/2011-01/31/2012 Targeting Adenovirus for Uterine Leiomyoma Gene Therapy. Diversity supplement to evaluate Adeno-CRAD for gene therapy of uterine fibroids
ZPU-305 Al-Hendy (PI), Repros Therapeutics Inc. 07/01/2008-08/30/2011A Phase III, open-label, Parallel, Randomized multicenter study evaluating the safety of 25, and 50 mg Proellex (CDB-4124) in the treatment of premenopausal women with symptomatic uterine fibroids.
5G12RR003032-21 Townsel (PI), NIH/NCRR 8/1/05-7/31/2010Meharry Research Center in Minority Institution Program (RCMI)Role on Program: Scientific Director, Meharry Center for Women Health Research
U54 HD044315-05 Nowicki (PI), NIH/NICHD 11/01/2007-08/31/2010 (NCE) Cooperative Center for Research in Reproduction , Role: PI, Project II: The effect of Oral Contraceptives and Endogenous Sex Steroids on uterine leiomyoma
NIH/NCRR, 1U54RR026140-01, Al-Hendy (Contact PI) 09/01/2009-03/01/2010 Meharry Clinical and Translational Research Center (MeTRC)
National Institute of Health (NICHD), 1R01HD046228-01, Title: Estrogen dependency of uterine leiomyoma. PI, Ayman Al-Hendy, M.D., Ph.D., $1,500,600, 2003–2008 (NCE to 2009)
National Institute of Health (NICHD), 1 R21HD46639-01, Title: Reversal of Infertility in Ovarian Failure. PI: Ayman Al-Hendy M.D., Ph.D., $ 420,000, 2005-2008
TAP Pharmaceutical Products, Inc., Title: Phase III clinical trial J867 for treatment of uterine leiomyoma. Ayman Al-Hendy M.D., Ph.D., is the site PI for this clinical trial of a novel selective progesterone receptor modulator (SPRM), $525,000, 2002–2007
US Department of Agriculture (USDA), BI09-005-001, Title: Gene Therapy of Peritoneal Adhesions. PI, Ayman Al-Hendy, M.D., Ph.D., $55,860, 2006–2007
Clinical Teaching and Research Grant, Title: Molecular genetics of repeated spontaneous twining. Granting Body: College of Medicine, University of Saskatchewan, Canada $30,000.00, 1999-2000
Canadian Foundation for Women’s Health Research Grant, Title: Molecular genetics of polycystic ovarian disease. Granting Body: Canadian Foundation for Women’s Health, Ottawa, Canada $10,000.00, 1999-2000
Clinical Teaching and Research Grant, Title: Gene therapy of ovarian cancer. Granting Body: College of Medicine, University of Saskatchewan, Canada $30,000.00, 1997-1999
APOG/SERONO Resident Research Grant, Title: Developing an animal model for epithelial ovarian cancer. Granting Body: The Association of Professors of Obstetrics and Gynecology, Canada, $6,000.00, 1996-1997
APOG/SERONO Resident Research Grant, Title: Gene therapy of epithelial ovarian carcinoma. Granting Body: The Association of Professors of Obstetrics and Gynecology, Canada $6,000.00, 1995-1996
PATENTS:
1. US patent No. 15/452,854. Stem cell therapy for ovarian failure.
2. US Pat No. 9,790,562 B2. Compositions and methods for the detection or treatment of uterine leiomyosarcoma.
3. US patent (pending). Targeted adenovirus mediated therapy for peritoneal adhesions
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4. US patent No. 60/365,760. Adenovirus mediated therapy for uterine conditions.
5. US provisional patent No. 60/245,030 Follistatine mutations and polycystic ovary syndrome.
6. US provisional patent No. 60/600,078. Methods and compositions for the prevention and treatment of preterm labor and uterine diseases or conditions.
7. US provisional patent No. 61/302,700. Vaginal rings/devices for treatment of uterine fibroids.
1. “Green Tea extract: a non-surgical alternative for treatment of uterine fibroids”. www.Clinicaltrials.gov identifier No. NCT01311869. Role: Principal Investigator.
2. A Study to Evaluate the Effects of Asoprisnil(J867) in Women With Uterine Fibroids Who Are Scheduled for a Hysterectomy. NCT 00150644. Role: Site Principal Investigator.
3. Safety of Treatment of Uterine Fibroids With Asoprisnil. NCT 00156208. Role: Site Principal Investigator.
4. Study of Asoprisnil in the Treatment of Uterine Fibroids. NCT 00160459. Role: Site Principal Investigator.
5. Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids. NCT 00853567. Role: Site Principal Investigator.
6. Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids. NCT 00735553. Role: Site Principal Investigator.
7. A Long-Term Safety Study of Asoprisnil in the Treatment of Uterine Fibroids. NCT 00156182. Role: Site Principal Investigator.
8. To Evaluating the Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of Uterine Fibroid Symptoms in Premenopausal Women. NCT 00874302. Role: Site Principal Investigator.
9. Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids. NCT 00156195. Role: Site Principal Investigator.
10. Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids. NCT 00737282. Role: Site Principal Investigator.
11. Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids. NCT 00156195. Role: Site Principal Investigator.
12. Two Year Extension Study of the Selective Progesterone Receptor Modulator Proellex® (CDB-4124) in Pre-Menopausal Women With Symptomatic Leiomyomata Who Have Previously Completed Study ZPU 003. NCT 00958334. Role: Site Principal Investigator.
13. An Open-label Study of the Effects of Elagolix in Adult Premenopausal Females. Abbott/Neuroscrine Biosciences (M12-663). NCT01403038. Role: Site Principal Investigator.
14. Efficacy and Safety Study of Ulipristal Acetate in Females With Anemia Associated With Uterine Leiomyoma. Watson Pharmaceuticals. NCT01553123. Role: Site Principal Investigator
15. A Prospective, Single-blind, Randomized, Phase III Study to Evaluate the Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) as an Adjunct to Hemostasis During Soft Tissue Open Surgeries. Instituto Grifols, S.A. (Spain). NCT00684047. Role: Site Principal Investigator
16. A randomized, open-label, active-controlled, multicenter trial to assess the contraceptive efficacy and general safety of the oral commercial nomegestrol acetate (MK-9271/SCH900618/Org 10486-0) – 17ß estradiol (MK-8175/SCH900175/Org 2317) batch. Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. NCT01448291 Role: Site Principal Investigator
17. An Open-label Study of the Effects of Elagolix in Adult Premenopausal Females. Abbott/Neuroscrine Biosciences (M12-813). NCT01403038. Role: Site Principal Investigator.
18. The Evaluation of Safety and Efficacy of Proellex in the Treatment of Pre-Menopausal Women With Confirmed, Symptomatic Uterine Fibroids. Repros Therapeutics Inc. ClinicalTrials.gov Identifier: NCT01728454. Role: Site Principal Investigator.
19. Phase 3 study of the Effects of Elagolix in Adult Premenopausal Females. Abb-Vie (M12-817). NCT01403038. Role: Site Principal Investigator.
20. Rejuvenation of Premature Ovarian Failure With Stem Cells (ROSE). ClinicalTrials.gov Identifier: NCT02696889. Sponsor: MD Stem Cells. Role: Site Principal Investigator. https://clinicaltrials.gov/ct2/show/NCT02696889?term=al-hendy&rank=1
i. Consultant, Royal College of Obstetrician and Gynecologist (RCOG, UK), Scientific Advisory Committee, 2017-Present
ii. NIH Integrative & Clinical Endocrinology and Reproduction study section (ICER), Chair, 2013-2015
iii. American society of Reproductive Medicine (ASRM), Research Committee. Chair. 2016-2019
iv. Vice-Chair, Health Disparity special interest group (HDSIG), American society of reproductive medicine, 2016-2017
v. NIH/NICHD, Leader, Fibroid group, Eunice Kennedy Shriver National Institute of Child Health and Human Development. Scientific Vision Meeting of the Gynecologic Health and Disease Branch (GHDB), Building 60, The Cloisters/Mary Woodard Lasker Center, Lecture Hall, National Institutes of Health, May 5-6, 2016.
vi. NIH/NICHD special emphasis panel ZHD 1 DRG-S (55) R, Special Topic: P50, National Centers for Translational Research in Reproduction and Infertility (NCTRI), Feb 29-March 2, 2016.
vii. NIH/CSR special emphasis panel ZRG1 ICER S, March 28, 2016. viii. Society of Reproductive Investigations (SRI) SRI-365 committee, Member, 2016-
xiii. External Advisory Committee, Morehouse school of Medicine, Jan 21-23, 2015, member.
xiv. Society of Reproductive Investigations (SRI) publication committee, Member, 2015-Present
xv. Society of Reproductive Investigations (SRI) Career Development committee, Member, 2015-Present
xvi. NIH/NICHD special emphasis panel ZHD 1 DSR-L BS1, P01, Special Topic: P01 Project Program, March 13, 2014.
xvii. NIH/NICHD special emphasis panel ZHD1 DSR-L 55 1, U10, Special Topic: Reproductive Medicine Network (RMN), May 13, 2013.
xviii. NIH special emphasis panel ZRG1 EMNR-E 90 S, R15, Special Topic: Metabolic Disease and Reproductive Biology, March 2012 and July 2012.
xix. NIH ZHD1 DSR-K (Loan Repayment) study section, Ad Hoc member, April 2010-April 2012
xx. American society of Reproductive Medicine (ASRM), Research Committee. Member. 2010-2019.
xxi. American society of Reproductive Medicine (ASRM), Membership Committee. Member. 2010-2012.
xxii. NIH Integrative & Clinical Endocrinology and Reproduction study section (ICER), Full Member, 2010-2015
xxiii. Chair, Health Disparity special interest group (HDSIG), American society of reproductive medicine, 2014-2015
xxiv. Vice-Chair/Chair-Elect, Health Disparity special interest group (HDSIG), American society of reproductive medicine, 2012-2014
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xxv. Chair-Programs, Fibroid special interest group (FSIG), American society of reproductive medicine, 2012-2015
xxvi. Member-nomination committee, Regenerative Medicine & Stem cells special interest group (RMSIG), American society of reproductive medicine, 2012-2014
xxvii. NIH Integrative & Clinical Endocrinology and Reproduction study section (ICER), Vice Chair Feb 2012
xxviii. NIH Integrative & Clinical Endocrinology and Reproduction study section (ICER), Vice Chair Oct 2011
xxix. NIH ZRG 1EMNR-P (50) R Translational Research in Pediatric and Obstetric Pharmacology study section, Ad Hoc member and Co-Chair, July 2010.
xxx. NIH ZHD1 DSR (Loan Repayment) study section, Ad Hoc member, April 2010.xxxi. NIH Integrative & Clinical Endocrinology and Reproduction study section (ICER), Ad
Hoc member, Feb 2010xxxii. NIH Special Emphasis Panel/Scientific Review Group, ZHD1-DSR-L-14, 2009/11,
WRHR program, Nov 16, 2009 meeting, Ad Hoc memberxxxiii. NIH Special Emphasis Panel/Scientific Review Group 2009/11, NIH Supported
Centers for Population Health and Health Disparities (CPHHD) P50, Sept 21-23, 2009 meeting, Ad Hoc member
xxxiv. NIH Special Emphasis Panel/Scientific Review Group 2009/10 ZRG1 EMNR-C (58) R meeting, June 11, 2009. Ad Hoc member
xxxv. Chair-elect, Fibroid special interest group (FSIG), American society of reproductive medicine, 2008-2009.
xxxvi. Chair, Fibroid special interest group (FSIG), American society of reproductive medicine, 2009-2010.
xxxvii. Member, nomination committee, Health Disparity special interest group (HD-SIG), American society of reproductive medicine, 2011-2012.
xxxviii. NIH Integrative & Clinical Endocrinology and Reproduction study section (ICER), Ad Hoc member, Feb 2008
xxxix. Chair, Research subcommittee, NCRR RCMI Translational Research Network (RTRN), 2007- 2009.
xl. Society for the Study of Reproduction (SSR): Clinical Outreach Committee. Member, 2007 - 2009.
xlii. NIH/NICHD U54 special emphasis group, Specialized Cooperative Centers for Reproduction and Infertility Research (SCCPRIR), 2007, 2013
xliii. NIH Pregnancy & Neonatology Study section (PN), Ad Hoc member, June 2005.
B. Local (Institute/Department/Hospital):
1. Augusta University/Georgia Regents University, Medical College of Georgia (MCG), Dean Council, Augusta, Georgia, 2014-20172. Augusta University/Georgia Regents University, Reviewer, intramural grant program, Augusta, Georgia, 2016-20173. Augusta University/Georgia Regents University, Medical College of Georgia (MCG), Department of Obstetrics and Gynecology, member, Executive Committee, Augusta, Georgia, 2014-2017
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4. Augusta University/Georgia Regents University, Medical College of Georgia (MCG), Department of Obstetrics and Gynecology, member, Academic Promotion and Tenure (APT) Committee, Augusta, Georgia, 2014-20175. Meharry-Vanderbilt Clinical and translational Science Award (CTSA): scientific review committee, member, 2007 – 2009, Nashville, Tennessee6. Meharry-Vanderbilt K-awards: scientific review committee, member, 2007 – 2013, Nashville, Tennessee7. Meharry Center for women health research: Operation & Staff committee, Chair, 2007 – 2014, Nashville, Tennessee8. Meharry Center for women health research: Internal advisory board, Chair, 2007 – 2014, Nashville, Tennessee9. Meharry Center for women health research: Scientific review committee, Chair, 2007 – 2014, Nashville, Tennessee10. Meharry Center for women health research: Membership committee, Chair, 2007 – 2014, Nashville, Tennessee11. Meharry Center for women health research: Community and advisory board, member, 2007 – 2014, Nashville, Tennessee12. Meharry Department of Obstetrics and Gynecology : Research committee, Chair, 2007 – 2014, Nashville, Tennessee13. Meharry Department of Obstetrics and Gynecology: Executive faculty committee, member, 2007 – 2014, Nashville, Tennessee14. Meharry Department of Obstetrics and Gynecology : Education committee, member, 2007 – 2014, Nashville, Tennessee15. Meharry Department of Obstetrics and Gynecology Finance & Governance committee, member, 2007 – 2014, Nashville, Tennessee16. Meharry School of Medicine: Executive faculty committee, member, 2007 – 2012, Nashville, Tennessee17. Meharry RCMI Internal advisory committee, member, 2007 – 2012, Nashville, Tennessee18. Meharry RCMI Executive Advisory committee, member, 2007 – 2012, Nashville, Tennessee19. Nashville General Hospital, staff wellness committee, 2008 – 2011, Nashville, Tennessee.20. UTMB OR Committee, Member, 2005 – 2007, Galveston, Texas.21. UTMB Institutional Review Board (IRB), Member, 2003-2004, Galveston, Texas.
TEACHING RESPONSIBILITIES
Junior Medical Student Lectures, Junior Medical Student Advisory Meetings, Examination Preparation for Junior Medical Student Clerkship, Instructor for 2nd Year Practice of Medicine Course, Obstetrics & Gynecology and Family Medicine Resident Didactic. Teach “General Gynecology” to Medical Students and Residents, Supervise clinical, surgical, and bedside training during general Obstetrics and Gynecology rotations. Annual GREOG questions marathon.
MEMBERSHIP IN SCIENTIFIC SOCIETIES:
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2016-Present Society of Reproductive Surgeons (SRS), Member
2012-Present American Gynecological Obstetrical Society (AGOS), Active Member
2001-Present Society for Gynecologic Investigation (SGI), Member
2003-Present American College of Obstetricians and Gynecologists (ACOG), Fellow
2003-Present American Society of Reproductive Medicine (ASRM), Fellow
2005-Present Society for the study of Reproduction (SSR), Member
2000-Present American Society of Gene and Cell Therapy (ASGCT), Member
2010-Present American College of Physician Executives (ACPE), Member
2011-Present Society of Clinical Research Associates, Member (ID # 41751)
2000-Present The Royal College of Physicians and Surgeons of Canada (RCSC), Fellow
1995-Present Society of Obstetricians and Gynecologists of Canada (SOGC), Fellow
2001-Present Texas Association of Obstetricians and Gynecologists (TAOG), Member
2012-Present The Academy of Breastfeeding Medicine, Member
1995-2001 Islamic Medical Association of North American Inc. (IMANA), Member
2002-2003 American Professors of Gynecology and Obstetrics (APGO), Member
2000-2002 The Society for the Investigation of Early Pregnancy (SIEP), Member
1998-1999 District VI, Saskatchewan Sections of American College of Obstetricians and Gynecologists (ACOG), Vice Chair, Junior Fellows
1998-2000 Canadian Society of Clinical Investigation (CSCI), Member
1998-2001 Central Regional Committee, Society of Obstetricians and Gynecologists of Canada (SOGC), Member
1998-2000 Junior Members Committee, Society of Obstetricians and Gynecologists of Canada (SOGC), Member
1995-2000 Canadian Medical Association (CMA), Member
1995-2000 Saskatchewan Medical Association (SMA), Member
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1994-1995 Canadian College of Medical Geneticists (CCMG), Member
1994-2000 Canadian Society of Biochemistry and Molecular Biology (CSBMB), Member
1992-1995 American Society of Human Genetics (ASHG), Member
1989-1992 Nordic Molecular Biology Association (NOMBA), Member
1988-1992 Turku Microbiological Society (TMS), Member
1990-1991 International Endotoxin Society (IES), Member
HONORS & AWARDS
1. 2018 Pfizer‐SRI President’s Presenter’s Award to mentee Abdeljabar El Andaloussi. SRI 65th Annual Scientific Meeting, San Diego, CA, March 6 – 10, 2018.
2. 2018 Pfizer‐SRI President’s Presenter’s Award to mentee Ihor Atabiekov. SRI 65th Annual Scientific Meeting, San Diego, CA, March 6 – 10, 2018.
3. American Society of Reproductive Medicine (ASRM) 2017 Service Milestone Award, ASRM Scientific Congress & Expo, San Antonio, TX, Oct 28-Nov 1, 2017
4. American Society of Reproductive Medicine (ASRM) 2017 Star Award, ASRM Scientific Congress & Expo, San Antonio, TX, Oct 28-Nov 1, 2017
5. Pfizer Mentor Luncheon, Society of Reproductive Investigation (SRI) 2017, mentee: Dr. Abdel Jabar El Andaloussi won 2017 SRI President’s presenter award.
6. Prize session presentation Dr. Qiwei Yang (Mentor: Dr. Ayman Al-Hendy), 72nd American society of reproductive medicine annual meeting, Salt Lake city, UTAH, USA, Oct 15-19, 2016
7. Best Presentation Award, Health Disparity Special Interest Group to Dr. Qiwei Yang (Mentor: Dr. Ayman Al-Hendy), 72nd American society of reproductive medicine annual meeting, Salt Lake city, UTAH, USA, Oct 15-19, 2016
8. 2016 Fertility and Sterility Investigator Achievement Award, 72nd American Society of Reproductive Medicine, Salt Lake City, UTAH, USA. Mentee: Dr. Shahinaz Shalaby.
9. Best Poster Prize Award, Society of Reproductive Investigations (SRI) 62nd annual meeting. March 15-19, 2015. Montreal, Quebec, Canada Mentee: Dr. Mostafa Khater.
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10. Training Award to Dr. Sara Mohamed (Mentor: Dr. Ayman Al-Hendy), 71st American society of reproductive medicine annual meeting, Baltimore Convention & Exhibition Center, Baltimore, Maryland, USA, Oct 17-22, 2015
11. Training Award to Dr. Soumia Brakta (Mentor: Dr. Ayman Al-Hendy), 71st American society of reproductive medicine annual meeting, Baltimore Convention & Exhibition Center, Baltimore, Maryland, USA, Oct 17-22, 2015
12. Prize session presentation Dr. Sara Mohamed (Mentor: Dr. Ayman Al-Hendy), 71st American society of reproductive medicine annual meeting, Baltimore Convention & Exhibition Center, Baltimore, Maryland, USA, Oct 17-22, 2015
13. Best Presentation Award, Health Disparity Special Interest Group to Dr. Sunil Halder (Mentor: Dr. Ayman Al-Hendy), 71st American society of reproductive medicine annual meeting, Baltimore Convention & Exhibition Center, Baltimore, Maryland, USA, Oct 17-22, 2015
14. Travel Award to Dr. Aymara Mas (Mentor: Dr. Ayman Al-Hendy), 71st American society of reproductive medicine annual meeting, Baltimore Convention & Exhibition Center, Baltimore, Maryland, USA, Oct 17-22, 2015
15. Best Poster Prize Award, Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA, Mentee: Dr. Aymara Perucho Mas.
16. Recipient of The Rogerio A. Lobo Award for the year 2015. This award was established in 2007 to recognize the most outstanding contribution to Reproductive Sciences by a member of the Society for Reproductive Investigations (SRI), previously known as the Society of Gynecologic Investigations.
17. Recipient of 2015 President Achievement Award, The Society for Reproductive Investigations (SRI), previously known as the Society of Gynecologic Investigations.
18. Teaching Excellence, NIH workshop, “Frontiers in Aging and Regeneration Research: Translating MSTEM in aging research from the lab to the clinic and beyond”, Morehouse School of medicine, Atlanta, GA, May 11-16, 2014.
19. Alpha Omega Alpha (AOA), clinician-Scientist of Year, Visiting Professorship, Atlanta, Georgia, April 22-23, 2014.
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20. Keynote speaker, the inaugural lecture of Dr. Sidney A. McNairy, Jr. Science of Disease Lecture Series. Morehouse School of Medicine, April 23, 2014.
21. 2012 Top Obstetrician & Gynecologist, Nashville, Tennessee, selected by the International Association of Obstetricians and Gynecologists, 410 Park Avenue, New York, NY 10022, USA.
22. Recipient of the 2010 IRA and ESTER ROSENWAKS New Investigator Award by the American Society of Reproductive Medicine.
23. Best publication award 2009, Misr El-Kheir Foundation.
24. Member of the team of “Meharry Researchers” who won “Tennessean of The Year, 2009 Award”, announced on December 27, 2009.
25. SREI (Society of Reproductive endocrinology and infertility) prize paper, ASRM (American society of Reproductive Medicine) 2009, mentee: Dr. Mohsen Ghadami.
26. Wyeth-SGI Mentor Luncheon, Society of Gynecologic Investigation (SGI) 2009, mentee: Dr. Mohsen Ghadami won 2009 SGI President’s presenter award.
27. Wyeth-SGI Mentor Luncheon, Society of Gynecologic Investigation (SGI) 2008, mentee: Dr. Mohsen Ghadami won 2008 SGI President’s presenter award.
28. America’s Top Obstetricians and Gynecologists, published by Consumers’ Research council of America, 2004, 2006, 2013.
29. Wyeth-SGI Mentor Luncheon, Society of Gynecologic Investigation (SGI) 2006, mentee: Dr. Essam Rashad Othman won 2006 SGI President’s presenter award.
30. Golden Apple Teaching Award, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, June 2003.
31. Berlex Foundation Faculty Development Award, 2003.
32. Burroughs Wellcome Fund Clinical Scientist Award in Translational Research (finalist), Nominated by School of Medicine, University of Texas Medical Branch, Galveston, Texas, 2003
33. American College of Obstetricians and Gynecologists, Junior Fellow Prize Paper Presentation, ACOG District VI Meeting, Maui, Hawaii, Oct. 26-29, 1999
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34. Medical Research Council of Canada and Canadian Society of Clinical Investigations, Annual Resident Research Award, Ottawa, Ontario, Canada, 1998
35. Society of Obstetricians and Gynaecologists of Canada, Junior Member Elective Fellowship Award, Ottawa, Ontario, Canada, 1998
36. Peter Vernon Clinical Fellowship in Gynecologic Oncology, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Toronto, Toronto, Canada, 1998
37. Second Prize, Annual Resident Research Day, Department of Obstetrics and
Gynecology, University of Saskatchewan, Saskatchewan, Canada, June 11-12, 1998.
38. First Prize Paper, 46th American College of Obstetrics and Gynecology, Annual Clinical Meeting, New Orleans, Louisiana, May 9-13, 1998
39. First Prize, Annual Resident Research Day, Department of Obstetrics and Gynecology, University of Saskatchewan, Saskatchewan, Canada, June 12-13, 1997
40. Post-Doctoral Clinical Award (Finalist) of the American Society of Human Genetics, Montréal, Québec, Canada, October 18-22, 1994
41. The Honourary Medal of Nagoya University School of Medicine, Scientific Day, Showa-Ku, Nagoya, Aichi 466, Japan, September 27, 1990
42. Young Investigator Award, First Congress of International Endotoxin Society, San Diego, California, May 10-12 1990
43. The Honourary Medal of Egyptian Medical Syndicate, Physician Day, Cairo, Egypt, March 18, 1988
SCHOLARSHIPS
1. Several Travel Awards, College of Medicine, University of Saskatchewan, Saskatoon, Canada, 1996-1998
2. Research Fellowship, Montréal Children’s Hospital Research Institute, McGill University, Montréal, Québec, Canada, 1994-1995
3. Scholarship, Arab Student Aid International, P.O. Box 10, Fanwood, New Jersey 07023, 1988-1991
4. Thesis Grant, Egyptian Ministry of Education, 7th floor, Tahrir Square, Cairo, Egypt, April 1992
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5. Grant, Turku University Foundation, Yliopistonkatu 24 B, 20100 Turku, Finland, April 1989, May 1991, and February 1992
6. Scholarship, Sigrid Juselius Foundation, C/O Turku University, 20500 Turku, Finland, 1989-1990, 1990-1991, and 1991-1992
7. Award, Emil Ja Bilda Maunulan Foundation, C/O Turun Yliopisto, Laaketieteellinen Tiedekunta, Lemminkaisenkatu 1, 20520 Turku, Finland, April 1990
8. Grant, Apteekkari Waino Edvard Miettisen Foundation, C/O Turku University, 20500 Turku, Finland, May 1991
9. Travel Award, Turun Yliopisto, Kliinis-Teoreettinen Laitos, Kiinamyllynkatu 10, 20520 Turku, Finland, February 1990, November 1990, and March 1991
10. Travel Award, Turku University Foundation, Yliopistonkatu 24 B, 20100 Turku, Finland, May 1990, and November 1991
11. Travel Award, Sigrid Juselius Foundation, C/O Turku University, 20500 Turku, Finland, June 1990
ADDITIONAL INFORMATION:
EDITOR (2016 – Present)1. SRI 1st-Alert, Society of Reproductive Investigations (SRI)
ASSOCIATE EDITOR (2017 – Present)1. BioMed Central (Perinatology & Neonatology)2. J Contraception & Reproductive Medicine
EDITORIAL/ADVISORY BOARD2. Fertility & Sterility 3. Reproductive Sciences4. Insights of Regenerative Medicine5. Obstetrics & Gynecology cases- Review6. Journal of Medical & Clinical Investigations7. Biomed Central (Maternal Health, Perinatology & Neonatology)8. WebmedCentralPlus9. Global Science and Technology Forum, Journal of Obstetrics &
Gynecology Procedures (GSTF-JOGP)10. Asian Pacific Journal of Reproduction (APJR)11. WebmedCentral,
1. Acta Pathologica Microbiologica Immunologica Scandenavica (APMIS)2. Acta Pharmacologica Sinica 3. American Journal of Obstetrics and Gynecology (Gray Journal)4. Annals of Internal Medicine5. Biology of Reproduction6. Cell & Tissue Research7. Cellular Physiology and Biochemistry8. Endocrinology9. Expert Opinion on Drug Discovery10. European Journal of Obstetrics, Gynecology, and Reproductive Biology11. F1000 Faculty Review (formerly F1000Prime Reports)12. Free Radical Biology & Medicine13. Gynecological and Obstetric Investigations (GOI)14. Gynecologic Oncology15. Human Reproduction16. Integrative Cancer Therapies17. International Journal of Obstetrics and Gynecology18. John Hopkins Advanced Studies in Medicine19. Journal of Clinical Endocrinology and Metabolism20. Journal of Comparative Effectiveness Research21. Journal of Gynecologic Research22. Journal of Nutrigenetics and Nutrigenomics23. Journal of Ovarian Research24. Journal of Society of Gynecologic Investigations.25. Journal of Women Health26. Molecular Carcinogenesis27. Molecular Endocrinology28. Molecular Human Reproduction29. Molecular Nutrition and Food Research30. Nature/Scientific Reports31. Nature/Reviews Disease Primers32. Neoplasia33. Neural Regeneration Research34. Obstetrics Gynecology International35. PlosOne36. Reproduction37. Reproductive Toxicology38. Stem Cell Investigation39. Stem Cell Research & Therapy40. Stem Cell Reviews and Reports41. Surgical Sciences (SS)42. System Biology in Reproductive Medicine43. Therapy44. Women’s Health (Future Medicine)45. Judge, the Cell Biology Forum, University of Texas Medical Branch, Galveston,
Texas, October 2, 2001
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46. Judge, Women’s Health Week Scientific Forum, Moody Gardens Hotel, Galveston, Texas, May 14, 2003
47. Center for Interdisciplinary Research on Women Health, Small Research Grant Competition, 2003-2004
48. Judge, Second Women’s Health Week Scientific Forum, University of Texas Medical Branch, Galveston, Texas, May 12, 2004
49. National Medical Student Forum, 2006.50. External Reviewer, Wayne University, APT committee, 2006.51. Society of Gynecologic Investigations (SGI)/ Society of Reproductive Investigations
(SRI) Abstract competition reviewer, 2007-Present.52. Vanderbilt-Meharry CTSA Studio expert panel, 2009-2011.53. Vanderbilt-Meharry CTSA Scientific review committee, 2007-2009.54. Chair, Fibroid special interest group abstract committee, American Society of
Reproductive Medicine (ASRM) abstract program, 2010.55. Fibroid special interest group abstract committee, American Society of Reproductive
Medicine (ASRM) abstract program, 2013.56. Society of Gynecologic Investigations (SGI)/Society of Reproductive Investigations
(SRI) Poster Judging, 2011, 2013, 2014, 201657. American Society of Reproductive Medicine (ASRM), Abstract competition, 2011,
1. Mentor and supervisory chair, Ms. Lauren Prusinski, MD PhD student, Title: Role of Developmental reprograming of DNA repair genes in predisposition to Uterine Fibroids in African Americans. Augusta University, Graduate School, Molecular Medicine program, 2015 – 2018. Graduated with distinction, April 2018.1 F30 HD089585-01, Early environmental and hormonal exposures and race-related influences on the human myometrial Stro1+/CD44+ stem cell population. Score 29% (Funding decision pending May 2017 council), 2017-2022.
2. Mentor and supervisory chair, Mr. Mostafa Khater, PhD student, Title: Developing an office non-invasive molecular imaging tool to differentiate between benign versus malignant uterine tumors. Augusta University, Graduate School, Molecular Medicine program, 2016 – Present.
3. Member, Ms. Elizabeth Vargis, Title: Correlating Raman spectra with changes that occur in the normal cervix: confounding factors and pregnancy, Ph.D. Candidate, (Supervisor: Dr. Anita Mahadevan-Jansen), Vanderbilt University, 2007–2012
4. Supervisory Chair, Ms. Sana Salih MD, Title: Catechol-O-Methyl Transferase Enzyme in the female Genital Tract, MMS Candidate, UTMB, 2005 – 2007
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5. Member, Ms. Pawelczyk Edyta, Title: Toll-like receptor 4 (TLR4) in Gestational Infection and Preterm Labor, Ph.D. Candidate, (Supervisor: Dr. Bogdan Nowicki), UTMB, 2003–2004
POSTDOCTORAL FELLOWS/VISITING SCIENTISTS/MENTEES
(1) Dr. Ayse Gonca Imir, MD, Postdoctoral Research Scientist from Northwestern University, spent two weeks in our Laboratory at UTMB, Galveston, to learn specific techniques, June 2004(2)Dr. Rebecca A. Chilvers, Ob/Gyn resident, research elective, UTMB, Galveston, August 2005.(3) Dr. Mohsen Ghadami MD PhD, Postdoctoral Research Fellow, UTMB, Galveston, 2005-2008(4) Dr. Sama Azab, D. Pharma , Postdoctoral Research Fellow, UTMB, Galveston, 2005-2007(5) Dr. Essam Othman MD , Obstetrician/Gynecologist, Postdoctoral Research Fellow, UTMB, Galveston, 2005-2007(6) Dr. Sana Salih, MD, Obstetrician/Gynecologist, Reproductive Endocrinology & Infertility Fellow, UTMB, Galveston, 2004-2007(7) Dr. Hussein Atta , MD PhD, Visiting Scientist from El-Menia University, Egypt, spent two weeks in our Laboratory at UTMB, Galveston, to learn specific techniques, January 2006 & June 2007.(8) Dr. Marwa Kamel, D. Pharma., Postdoctoral Research Fellow, UTMB, Galveston, 2004-2005(9) Dr. Melissa Wentz PhD, Postdoctoral Research Fellow, UTMB, Galveston, 2004-2007(10) Dr. Salama Salama, PhD, Postdoctoral Research Fellow, UTMB, Galveston, 2002-2007(11) Dr. Memy Hassan, D. Pharma , Postdoctoral Research Fellow, UTMB, Galveston, 2006-2008(12) Dr. Dong Zhang, MD PhD, Postdoctoral Research Fellow, UTMB, Galveston, 2005-2008(13) Dr. Ebtehall El-Demerdash , PhD, Visiting Scientist from Ain Shams University, Egypt, in our Laboratory at UTMB, Galveston, to learn specific techniques, January 2007 – October 2007(14) Dr. Moon Hu , PhD, Visiting Scientist from Seol University, , in our Laboratory at UTMB, Galveston, to learn specific techniques, January 2007 – September 2007(15) Dr. Mohamed Awad, D. Pharma , Postdoctoral Research Fellow, UTMB, Galveston, 2007(16) Dr. Yang Hong PhD, Assistant professor, Center for women health research, Meharry Medical College, Nashville, Tennessee, 2007 – Present.(17) Dr. Venessa Elliot, PhD, assistant professor, clinical psychologist, Department of Family Medicine, Meharry Medical College, Nashville, Tennessee, 2007 – Present.(18) Dr. Ahsen Chaudary, MD, Urogynecologist, associate professor, Department of Obstetrics and Gynecology, Meharry Medical college, Nashville, Tennessee, 2007-2014.(19) Dr. Salama Abdelraheim, Biochemist, MD, assistant professor, Department of Biochemistry, El-Menia University, El-Menia, Egypt, spent two weeks in our Laboratory at Meharry Medical School, Nashville, to learn specific molecular biology techniques, April 2009.(20) Dr. Mohamed Abdel-Raheem Sabry, MD, Obstetrician/Gynecologist, assistant lecturer, Department of OB/GYN, Sohag University, Sohag, Egypt, predoctoral fellowship, joint supervision program, Meharry Medical School, Nashville, Tennessee, 2009-2012. (21) Dr. Ahmet Sahbaz, MD, Obstetrician/Gynecologist, Department of OB/GYN, Istanbul University, Turkey, predoctoral fellowship, joint supervision program, Meharry Medical School, Nashville, Tennessee, 2009-Present.
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(22) Dr. HoVan Nguyen, MD, postdoctoral research fellow, MMC, Nashville, 2009-2010. (23) Dr. Sangeeta Nair, DVM, postdoctoral research fellow, MMC, Nashville, 2008-2014.(24) Dr. C. Sharan, PhD, postdoctoral research fellow, MMC, Nashville, 2008-2014.(25) Dr. Waseem Khoder, MD, OB/GYN, Instructor, Department of Obstetrics and Gynecology, Meharry Medical college, Nashville, Tennessee, 2010-Present.(26) Dr. Eman Roshdy MD, Public Health specialist, assistant lecturer, Department of public health, Sohag University, Sohag, Egypt, predoctoral fellowship, Meharry Medical School, Nashville, Tennessee, 2009-2012(27) Dr. Sarbani Maitra MD, clinical research fellow, Meharry Medical School, Nashville, Tennessee, 2010-2013(28) Dr. Malika Nair MD, clinical research fellow, Meharry Medical School, Nashville, Tennessee, 2013-(29) Dr. Cassandra Rackauskas MD, clinical research fellow, Meharry Medical School, Nashville, Tennessee, 2013-(30) Ms. Ashley Underwood, clinical research fellow, Meharry Medical School, Nashville, Tennessee, 2012-201(31) Dr. Deepa Bhartiya PhD, Scientist and director of Stem cell laboratory (Mumbai, India), Visiting research Scholar, Meharry Medical School, Nashville, Tennessee, October, 2013(32) Dr. Shurook Elassouli MD, clinical research fellow, Meharry Medical School, Nashville, Tennessee, 2013-2014(33) Aymara Mas Perucho PhD, postdoctoral research fellow, Georgia Regents University, Augusta, Georgia, 2014-2015.(34) Sabry M. Attia, Ph.D. Professor of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh Saudi Arabia, http://faculty.ksu.edu.sa/73917/default.aspx, visiting scholar, Georgia Regents University, Augusta, Georgia, August 2014. (35) Sunil Halder, PhD, Assistant professor, Meharry Medical College, Nashville, Tennessee 2008-2014, Senior research scientist, Georgia Regents University, Augusta, Georgia, 2014-Present.(36) Chandra Thota, PhD, Assistant professor, Meharry Medical College, Nashville, Tennessee 2008-2014.(37) Archana Laknaur MSC, research fellow, Meharry Medical College, Nashville and Georgia Regents University, Augusta, Georgia, 2012-Present.(38) Mohamed Abdel Aziz Baz, MD, research fellow, Georgia Regents University, Augusta, Georgia, 2014-Present.(39) Sara Mohamed, MD, research fellow, Georgia Regents University, Augusta, Georgia, 2014-2015.(40) Shahinaz Shalaby, MD, research fellow, Meharry Medical College, Nashville and Georgia Regents University, Augusta, Georgia, 2013-2015.(41) Qiwei Yang, PhD, Senior research scientist, Georgia Regents University, Augusta, Georgia, 2014-Present.(42) Soumia Brakta, MD, Clinical research fellow, Georgia Regents University, Augusta, Georgia, 2014-Present(43) Mostafa Khater, D Pharmacy, research fellow, Georgia Regents University, Augusta, Georgia, 2014-Present.(44) Heba Hassan, MD, research fellow, Georgia Regents University, Augusta, Georgia, 2014-2016.(45) Marwa Badr, MD, Clinical fellow, Georgia Regents University, Augusta, Georgia, Jan 2015- Oct 2015
(46) Ahmed Hisham, MD, Clinical fellow, Augusta University, Augusta, Georgia, Sept-Oct, 2016.(47) Huda Elhusseini, D Pharmacy, research fellow, Augusta University, Augusta, Georgia, 2016-Present.(48) Mohamed Ali, D Pharmacy, research fellow, Augusta University, Augusta, Georgia, 2016-Present.(49) Tarek Khalaf, MD, Clinical fellow, Augusta University, Augusta, Georgia, Aug – Sept 2016.(50) Prosper Igboeli, MD, Visiting scholar (Sabbatical), Augusta University, Augusta, Georgia, Sept 2016 - Present
MD-PhD/MEDICAL/PhD/COLLEGE/HIGH SCHOOL STUDENTS SUMMER RESEARCH TRAINEES
2002 John Thomas, medical student (University of Budapest)
2003 Mohamed Zaidan, college student (University of Houston)
2006 Michael Simmons (Texas City High School)
2007 Michael Simmons (Texas City High School)
2007 Mohamed Al-Hendy (Clear Brook High School)
2008 Ellana N. Stinson, medical student (Meharry Medical College)
2008 Rachael-Ann Joseph, medical student (Meharry Medical College)
2008 Anjali Khurana, medical student (Meharry Medical College)
2008 Sheena Pullman, medical student (Meharry Medical College)
2008 Christina Yi, medical student (Meharry Medical College)
2009 Tarannum Jaleel, medical student (Meharry Medical College)
2010 Ugochukwu Agwai, medical student (Meharry Medical College)
2010 Shandeidra Bonds, medical student (Meharry Medical College)
2010 LaVonne Hairston, medical student (Meharry Medical College)
2010 Tiffany Jones, medical student (Meharry Medical College)
2010 Natasha Lowe, medical student (Meharry Medical College)
2011 Nicole Pace, medical student (Meharry Medical College)
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2011 Letitia Lyons, medical student (Meharry Medical College) 2011 Kia Brown, medical student (Meharry Medical College) 2011 Lindsay Ross, medical student (Meharry Medical College) 2011 Jessica Lawrance, medical student (Meharry Medical College)
2013-2014 Teri-Lee Foster, medical student (Meharry Medical College)
2014 Justin Diamond, (University of Michigan)
2014 Mohamed Allakany (Masnoura University)
2014 Lauren Prusinski, MD/PhD student, Georgia Regents University
2015 David Stone, MD Student, Georgia Regents University2016 Jibade, Oluwaseyi (Trey), BSc, Augusta University
COURSES AND ELECTIVES:
January 2004 Berlex Foundation faculty Development Course, Captiva Island, Florida
November 2002 Applied Research Ethics National Association/Institutional Animal Care and Use Committee 101Atlanta, Georgia
November 1998 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Western Ontario, London, Ontario, Canada.
April 1998 Division of Gyn Oncology, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada.
March 1997 Advanced Labor Assessment and Risk Management (ALARM) course for high risk obstetrics, University of Saskatchewan, Canada.
May-June 1996 Dept of Obstetrics and Gynecology (Professor Nelly Auersperg), Vancouver Women’s Hospital, University of British Columbia, British Columbia., Canada
March 1996 Alan Blair Cancer Centre, Pasqua Hospital, Regina, Saskatchewan, Canada
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August 1995 Rural Obstetrics at Dept of Obstetrics & Gynecology, Victoria General Hospital, Prince Albert, Saskatchewan, Canada.
November 1991 European Molecular Biology Organization (EMBO) practical course "DNA Sequencing: Advanced Approaches, Automated Methods and Analysis", November 13-23, 1991, European Molecular Biology Laboratory, Heidelberg, Germany.
August 1988 Immunology Workshop, Ain Shams University, Cairo, Egypt.
May 1986 Clinical clerkship at 1st Surgery University Clinic, Vienna, Austria.
INVITED CLINICAL & RESEARCH PRESENTATIONS AND LECTURES:
1. Female Reproductive Research Program, Work in Progress seminar. Dept of Obstetrics
and Gynecology, College of Medicine, University of Illinois @ Chicago (UIC), Chicago, Illinois, August 6, 2018.
2.3. Bench to Bedside for Novel Medical Treatment Options of Uterine Fibroids. University
of Ottawa, Dept of Obstetrics and Gynecology, annual research day, Ottawa, Canada, May 11, 2018.
4. Gene/Stem Cell Therapy Applications in Female Reproduction: A Gynecologist-Scientist Journey. University of Ottawa, Dept of Obstetrics and Gynecology, annual research day, Ottawa, Canada, May 11, 2018.
5. Overexpression of a DENND1A Isoform Produces a Polycystic Ovary Syndrome Theca Phenotype. Department of Obstetrics & Gynecology, University of Illinois @ Chicago (UIC), Chicago, IL, May 7th, 2018.
6. Recent Advances in Medical Treatment of Uterine Fibroids. United Arab Emirates 7th annual infertility symposium. Dubai, UAE March 23-23, 2018.
7. Making your own: stem cell therapy of premature ovarian insufficiency. United Arab Emirates 7th annual infertility symposium. Dubai, UAE March 23-23, 2018.
8. Making your own: stem cell therapy of premature ovarian failure. Center for Stem Cell Biology, Dept of Pharmacology, College of Medicine, University of Illinois @ Chicago (UIC), Chicago, Illinois, Feb 27, 2018.
9. Female Reproductive Research Program, Work in Progress seminar. Dept of Obstetrics and Gynecology, College of Medicine, University of Illinois @ Chicago (UIC), Chicago, Illinois, Jan 8, 2018.
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10. Functional vascularized lung grafts for lung bioengineering. Journal Club. Department of Obstetrics & Gynecology, Augusta University, Augusta, Georgia, Nov 16, 2017.
11. Fertility Preservation using Selective Progesterone Receptor Modulators in Women with Uterine Fibroids. Luncheon Roundtable, 73rd American society of reproductive medicine annual meeting, Henry Gonzalez Convention Center, San Antonio, Texas, USA, Oct 28-Nov 1st, 2017
12. Current and Investigational Medical Management for Uterine Fibroids. Breakfast symposium, 73rd American society of reproductive medicine annual meeting, Henry Gonzalez Convention Center, San Antonio, Texas, USA, Oct 28-Nov 1st, 2017
13. Recent Advances in Medical Treatment of Uterine Fibroids. Postgraduate course, 73rd American society of reproductive medicine annual meeting, Henry Gonzalez Convention Center, San Antonio, Texas, USA, Oct 28-Nov 1st, 2017
14. Impact of Race on Uterine Fibroids Presentation & Progression. Postgraduate course, 73rd American society of reproductive medicine annual meeting, Henry Gonzalez Convention Center, San Antonio, Texas, USA, Oct 28-Nov 1st, 2017
15. Uterine Fibroids: A review of the Clinical and Financial Burden of Disease. AMCP Managed Care & Specialty Pharmacy Annual Meeting, Dallas, Texas, Oct 18, 2017.
16. Uterine Fibroids: A review of the Clinical and Financial Burden of Disease. Optumhealth Education Annual Meeting, Vegas, NV, Nov 9th, 2017.
17. Uterine Fibroids: A review of the Clinical and Economic Burden of Disease. Women in Government Annual Meeting, Washington DC, Nov 11th, 2017.
18. Vilaprisan: Treatment of HMB associated with Uterine Fibroids. Bayer Inc. Asteroid 3 and 4 Investigator Meeting, Dallas, Texas, Oct 25, 2017
19. Why are fibroids more common in women of color?, converting challenge into opportunity. National institute of health, NICHD Reproductive Health Group, Bethesda, MD, Sept 20, 2017.
20. Driver Mutations of Uterine Fibroids, Myovant European Investigators meeting, Berlin, Germany, July 7th, 2017.
21. Driver Mutations of Uterine Fibroids, Myovant North/South America Investigators meeting, Chicago, IL, April 21st, 2017.
22. Female Reproductive Research Program, Work in Progress seminar. Dept of Obstetrics and Gynecology, Medical College of Georgia. Augusta University, Augusta, Georgia, Feb 23, 2017.
23. Why Uterine Fibroids more common in women of color?. Grand Round. Department of Obstetrics and Gynecology. Yale University, New Haven, CT, Feb 24th, 2017.
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24. Selective Progesterone Receptor Modulators: Novel Oral Agents for Treatment of Uterine Fibroids. Grand Round. Department of Obstetrics and Gynecology. Augusta University, Augusta, Georgia, Nov 16th, 2016.
25. Prevention of uterine fibroids. Allergan Uterine Fibroid Task Force, Salt lake city, UTAH, USA, Oct 14, 2016.
26. Preferential epigenetic programming of estrogen response after in utero xenoestrogen(bisphenol-A) exposure. Journal Club. Department of Obstetrics & Gynecology, Augusta University, Augusta, Georgia, August 25th, 2016.
27. Female Reproductive Research Program, Work in Progress seminar. Dept of Obstetrics and Gynecology, Medical College of Georgia. Augusta University, Augusta, Georgia, June 30th, 2016.
28. Role of Driver Mutations in Uterine Fibroids, Bayer Fibroid symposium, Society of Reproductive Investigations (SRI) 63rd annual meeting. March 15-19, 2016. Montreal, Quebec, Canada
29. Connection Corners “Grantsmanship for Clinicians”, Society of Reproductive Investigations (SRI) 63rd annual meeting. March 15-19, 2016. Montreal, Quebec, Canada
30. Reprogramming of the Epigenome by MLL1 Links Early-life Environmental Exposuresto Prostate Cancer Risk. Journal Club. Department of Obstetrics & Gynecology, Georgia Regents University, Augusta, Georgia, December 10th, 2015.
31. Female Reproductive Biology Research Program, Work in Progress seminar. Dept of Obstetrics and Gynecology, Medical College of Georgia. Georgia Regents University, Augusta, Georgia, Sept 18th, 2015.
32. CAM for Uterine Fibroids: from Bench-to-Bedside-to-Community. Clinical and Translational Science Seminar, Dept of Biostatistics, Medical College of Georgia. Georgia Regents University, Augusta, Georgia, July 28th, 2015.
33. Gene and Stem Cell Therapy of Premature Ovarian Failure. Spring GRU Institute of Regenerative and Reparative Medicine (IRRM) Regenerative Medicine symposium. Regenerative Medicine and Cellular Therapy symposium. Georgia Regents University, Augusta, Georgia, April 24th, 2015.
34. Connection Corners “Mentoring MD/PhDs”, Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2016. San Francisco, CA, USA
35. Minority Biomedical Researchers (Reproductive Science & Women Health). Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
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36. O2 regulates stem cells through Wnt/B-Catenin Signaling. Journal Club. Department of Obstetrics & Gynecology, Georgia Regents University, Augusta, Georgia, March 5th, 2015.
37. Complementary Medicine for Uterine Fibroids: from Bench-to-Bedside-to-Community. Experimental Therapeutic Seminar series, PhD graduate program, Biomedical Sciences, Medical College of Georgia. Georgia Regents University, Augusta, Georgia, Feb 26th, 2015.
38. Complementary Medicine for Uterine Fibroids: from Bench-to-Bedside-to-Community. MD/PhD program PSR Session. Medical College of Georgia. Georgia Regents University, Augusta, Georgia, December 2nd, 2014.
39. Injectable Clostridium Histolyticum Collagenase as a Potential Treatment for Uterine Fibroids. Journal Club. Department of Obstetrics & Gynecology, Georgia Regents University, Augusta, Georgia, July 17, 2014.
40. Complementary Medicine for Uterine Fibroids: from Bench-to-Bedside-to-Community. MSP Session VIII-Faculty Seminar. Medical College of Georgia. Georgia Regents University, Augusta, Georgia, July 9th, 2014.
41. Premature Ovarian Failure: Challenges and Opportunities. . Grand Round. Department of Obstetrics and Gynecology. Georgia Regents University, Augusta, Georgia, June 11th, 2014.
42. Magnetic Nanoparticles Enhance Adenovirus Transduction In Vitro and In Vivo. Journal Club. Department of Obstetrics & Gynecology, Georgia Regents University, Augusta, Georgia, May 29, 2014.
43. Novel Non-Surgical Treatment for Uterine Fibroids. Sixth Paul G. McDonough Symposium. Georgia Regents University, Medical College of Georgia, Augusta, GA, May 16, 2014.
44. Premature Ovarian Failure: Challenges and Opportunities. In NIH workshop, “Frontiers in Aging and Regeneration Research: Translating MSTEM in aging research from the lab to the clinic and beyond”, Morehouse School of medicine, Atlanta, GA, May 11-16, 2014.
45. CAM & Uterine Fibroids: from Bench-to-Bedside-to-Community. Grand Round. Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, April 29th, 2014.
46. Molecular Medicine & Health Disparity: Turning Challenge into Opportunity. Morehouse school of Medicine (MSM) 26th Student Research Symposium, the Alpha Omega Alpha (AOA) Visiting Professor and the inaugural lecture of the Dr. Sidney A. McNairy, Jr. Science of Disease Lecture Series, Atlanta, Georgia, April 22-23, 2014.
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47. Hair Relaxer & Risk of Uterine Fibroids in African-American Women. Journal Club. Department of Obstetrics & Gynecology, Georgia Regents University, Augusta, Georgia, April 10th, 2014.
48. CAM for Uterine Fibroids: From Bench-to-Bedside-to-Community. Grand Round. Department of Obstetrics and Gynecology. Georgia Regents University, Augusta, Georgia, March 5th, 2014.
49. EZH2 phosphorylation activate STAT3 in Glioblastoma stem-like cells. Journal Club. Center for women health research, Meharry Medical College, Nashville, Tennessee, Jan 23, 2014.
50. Uterine fibroid murine model: An in vivo imaging approach. Journal Club. Center for women health research, Meharry Medical College, Nashville, Tennessee, December 12th, 2013.
51. Non-Hormonal Treatment for Uterine Fibroids. In, “Leiomyomata, clinical updates, Research Development, and disparities in disease, outcomes, and access to care”. postgraduate course, 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
52. Uterine Fibroids: Research Update. In, “Leiomyomata, clinical updates, Research Development, and disparities in disease, outcomes, and access to care”. postgraduate course, 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
53. Biology of Health Disparities. In the Health Disparity Interactive Session. 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
54. Epigenetic control of BCL2 in Breast Cancer. Journal Club. Center for women health research, Meharry Medical College, Nashville, Tennessee, Sept 5th, 2013.
55. The Role of Disregulated WNT/β-Catenin Pathway in Uterine Fibroids. In Fibroid lunchtime symposium “Novel Molecular Targets for Medical Treatment of Uterine Fibroids” 60th Annual meeting, Society of Gynecologic Investigation (SGI), , March 20-23, 2013.
56. Gene Therapy for Uterine Fibroids. Department of Obstetrics & Gynecology, University of Florida, Gainesville, Florida, January 25, 2013.
57. Speaker & Debater, Interactive session debate “Eliminating Uterine Fibroids: to prevent (Dr. Al-Hendy) or to Treat (Dr. Segars/Leppert)”, 68th annual meeting, American Society of Reproductive Medicine (ASRM), Dan Diego, California Oct 20-24th, 2012.
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58. Uterine Fibroids & Endometrial Dysfunction. 45th Annual Meeting, Society for Study of Reproduction (SSR), State College, Pennsylvania, August 12-15, 2012.
59. Medical Treatment of Uterine Fibroids. Department of Physiology and Obstetrics and Gynecology, Kansas City Medical Center, Kansas city, Missouri, May 14, 2012.
60. Novel Therapeutic Targets for Uterine Fibroids. Department of Obstetrics and Gynecology. Florida International University, Miami, Florida, February 15, 2012.
61. Medical Treatment of Uterine Fibroids. Grand Rounds, Department of Obstetrics and Gynecology. Howard University, Washington DC, December 8, 2011.
62. Non-Hormonal Treatment of Uterine Fibroids. Advances in Uterine Fibroids, Postgraduate course, 67th annual meeting, American Society of Reproductive Medicine (ASRM), Orlando, Florida, 15-19, 2011.
63. Pathology of Uterine Fibroids. Advances in Uterine Fibroids, Postgraduate course, 67th annual meeting, American Society of Reproductive Medicine (ASRM), Orlando, Florida, 15-19, 2011.
64. Genetics of Uterine Fibroids. Advances in Uterine Fibroids, Postgraduate course, 67th annual meeting, American Society of Reproductive Medicine (ASRM), Orlando, Florida, 15-19, 2011.
65. Medical Treatment of Uterine Fibroids. American Gynecologist and Obstetrician Society (AGOS), Chicago, Sept 14-17, 2011.
66. What is Research and Why Do We even Care?. HHS/NIH High School Mentorship Program, Nashville, Tennessee, June 24, 2011
67. Stem cells in Gynecology, Center for Women Health Research, Meharry Medical College, April 18, 2011.
68. Adenovirus-Mediated Overexpression of Human Tissue Plasminogen Activator Prevents Peritoneal Adhesions Formation/Reformation. 3rd International Conference on Drug Discovery & Therapy, February 7-10, 2011, Dubai Women’s College, Dubai, UAE.
69. Green Tea Extract for Treatment of Uterine Fibroids: From Bench to Bedside . 12th RCMI International symposium on health disparity, December 6-9, 2010, Nashville, Tennessee. http://rtrn.net/rtrn/presentations/Wednesday_December_8/Ayman.pdf
70. Green Tea Extract for Treatment of Uterine Fibroids: From Bench to Bedside. Advances in Uterine Leiomyoma Research: 3rd NIH International Congress, National Institutes of Health, November 22-23, 2010
71. Medical Treatment of Uterine Fibroids. On line interview/Webinar, WWW.Fibroidsproject.com, also on www.Facebook.com and, www.Twitter.com, October 2010.
72. Uterine fibroids & Adolescents: Opportunity for Early Intervention. Pediatric and Adolescent Gynecology Research Think Tank Panel meeting, NIH, May 27-28, 2010
73. Cultural Competence: Attending to female Muslim Patients in USA. Grand round, Department of Obstetrics and Gynecology, Meharry Medical College, Nashville, TN, February 11, 2010.
74. Green Tea Extracts for Treatment of Uterine Fibroids: From Bench to Bedside. Meharry translational and clinical research center (MeTRC) seminar series. Meharry Medical College, Nashville, TN, February 10, 2010.
75. Green Tea Extracts and Uterine Fibroids: From Bench to bedside. Grand round, Dept of Microbiology and Immunology, Meharry Medical College, Nashville, TN, December 11, 2009.
76. Chronic Pelvic Pain in Women. Grand round, Dept of Obstetrics and Gynecology, Meharry Medical College, Nashville, TN, December 11, 2008.
77. Chronic Pelvic Pain in Women. American Academy of Pain Management, 9th annual conference, Nashville, TN, September 10, 2008.
78. Serving Muslim Patients in America. Vanderbilt University. Nashville, TN, April 17, 2008.
79. Fibroids update. Healthcare for the women over 40, 20th annual James symposium in Obstetrics & Gynecology. Nashville, TN, April 4, 2008.
80. Adenovirus-Mediated Gene Therapy of Uterine Fibroids. NICHD Uterine fibroid research update workshop, NIH, Rockville, MD, Sept 18-19, 2007
81. Why are Uterine Fibroids More Common in African Americans? NICHD Uterine fibroid research update workshop, NIH, Rockville, MD, Sept 18-19, 2007.
82. Molecular Genetics of the Ethnic disparity in uterine leiomyoma. Wayne state University, Detroit, MI, March 28, 2007.
83. Why is uterine leiomyoma more common in black women?. Grand round. Baylor College of Medicine, Houston, TX, Jan 24th , 2007.
84. Molecular Genetics of the Ethnic disparity in uterine leiomyoma. Grand round. University of Michigan, Ann arbor, MI, Oct 19, 2006.
85. Cell and Gene Therapy in Gynecology. University of Michigan, Ann arbor, MI, Oct 19, 2006.
86. Stem cell therapy & Gynecology. Keynote lecture, 2nd international conference on stem cells. Trabzone, Turkey, Sept 6-9, 2006.
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87. Religious Differences in Our Workforce: Special Considerations in Healthcare Delivery, UTMB, Galveston, Texas, May 19, 2005.
88. Estrogen Metabolism: Is it a Black & White Thing?. Grand Round. University of Texas Medical Branch, Galveston, Texas, Feb 2, 2005.
89. Gene and Cell Therapy in Gynecology. Grand Round. Dept of Pharmacology, Ain Shams University, Cairo, Egypt, Dec 21, 2004.
90. Prevention of Laparoscopic Complications. Grand round, Dept of Obstetrics and Gynecology, Zagazig University, Zagazig, Egypt, Dec 19, 2004.
91. Chronic Pelvic Pain, a painful problem.. Grand Rounds, Department of Obstetrics and Gynecology, Kuwait University, Kuwait, Dec 13, 2004.
92. Ethnicity and Estrogen Metabolism. Microsymposium, March 27-28, 2004, University of Texas Medical Branch, Galveston, Texas.
93. Genetics and Gene Therapy of Uterine Leiomyomas. Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, March 11, 2004.
94. Prevention of Laparoscopic Complications. 2nd international Obstetrics and Gynecology conference, Al-Menia University, Egypt, March 3-4, 2004.
95. New Treatment of Uterine Leiomyoma. 2nd international Obstetrics and Gynecology conference, Al-Menia University, Egypt, March 3-4, 2004.
96. Genetics and Gene Therapy of Uterine Leiomyoma. Grand Rounds, Dept of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, Jan 20, 2004.
97. Gene and Cell Therapy in Gynecology. Grand Round. University of Texas Medical Branch, Galveston, Texas, June 16, 2004.
98. Genetics and Gene Therapy of Uterine Leiomyomas. Grand Rounds, Department of Obstetrics and Gynecology, Wayne University, Detroit, Michigan, October 21, 2003.
99. Chronic Pelvic Pain, a painful problem.. Grand Rounds, Department of Obstetrics and Gynecology, Wayne University, Detroit, Michigan, October 21, 2003.
100. Novel Therapeutics for Uterine Leiomyomas. Center for Interdisciplinary Research in Women Health, University of Texas Medical Branch, Galveston, Texas, April 10, 2003.
101. New Treatments of Uterine Leiomyomas. Department of Obstetrics and Gynecology, Kasr Al-Aini University, Cairo, Egypt, December 16, 2002.
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102. Contraception, Presentation to Armenian physicians via University of Texas Medical Branch Telemedia Program, June 13, 2002.
103. Gene Therapy Approach for Gynecologic (and Obstetric) Disorders. Women’s Reproductive Health Research Workshop. University of Texas Medical Branch, Galveston, Texas, December 20, 2000.
104. Gene Therapy for Ovarian Cancer. Invited speaker, American College of Obstetricians and Gynecologists, Annual District VI Meeting, September 21-23, 2000, Winnipeg, Manitoba, Canada.
105. Adenoviral Gene Therapy of Ovarian Cancer. Grand Rounds, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, January 5, 2000.
106. Gene Therapy of Epithelial Ovarian Cancer. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada, April 20, 1998.
107. Gonadotropin receptor structure/function in the ovary and clinical implications. Division of Reproductive Medicine, Department of Obstetrics and Gynecology, University of Western Ontario, London, Ontario, Canada, November 19, 1998.
108. Gene Therapy Using Encapsulated Cells. College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada, February 28, 1997.
109. Molecular Genetics of Yersinia Lipopolysaccharides. Baylor College of Medicine, Houston, Texas, September 22, 1993.
110. Molecular Genetics of Yersinia Lipopolysaccharides. Department of Microbiology, Zagazig University, Zagazig, Egypt, January, 1991.
NIH SCIENTIFIC ADVANCES
1. Why are uterine fibroids more common in African Americans? (R01 HD046228). Requested by: Dr. Estella Parrott, NICHD, 2006.
2. A Novel animal model for human uterine fibroids (G12 RR003032). Requested by: Dr. Shelia McClure, NCRR, 2008.
3. Green Tea Extract, a Potential Therapy for Uterine Fibroids (G12 RR003032 & R01 HD046228). Requested by: Dr. Estella Parrott, NICHD, 2010
4. Vitamin D shrinks fibroid tumors in rats. Thursday, March 1, 2012, Contact:Robert Bock or Marianne Glass Miller, 301-496-5133,
LEADER/ORGANIZER/COURSES/WORKSHOPS at NATIONAL & INTERNATIONAL CONFERENCES:
1. Speaker, organizer and Moderator, Allergan Fibroid Symposium, “Molecular Pathology of Uterine Fibroids” Department of Obstetrics and Gynecology. Augusta University, Augusta, Georgia, Nov 16th, 2016.
2. Speaker and Moderator, Roundtable Luncheon RTW09 “Fibroid Stem Cells and Developmental Epigenetic Reprogramming”, 72nd American society of reproductive medicine annual meeting, Salt Lake city, UTAH, USA, Oct 15-19, 2016
3. Organizer, chair & moderator, session, Diversity Career development Forum, Society of Reproductive Investigations (SRI) 63rd annual meeting. March 15-19, 2016. Montreal, Quebec, Canada
4. Organizer, chair & moderator, session, Innovative Mechanisms to Support Reproductive Research, Society of Reproductive Investigations (SRI) 63rd annual meeting. March 15-19, 2016. Montreal, Quebec, Canada
5. Organizer, chair & moderator, session “Abdominal myomectomy vs. laparoscopic myomectomy in the era of morcellation ban”, American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
6. Organizer, chair & moderator, session “Minority Career Development”, Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
7. Moderator, session on “Reproductive Biology, Laboratory”, 70th American Society of Reproductive Medicine annual meeting, Honolulu, Hawaii, USA, Oct 18-22, 2014
8. Organizer, NIH Sponsored Advanced Training Course Rehabilitative and Regenerative Medicine for Minority Health and Health Disparities (REMEDY), a Frontiers Advanced Training Course, June 24-27, 2014, Morehouse School of Medicine, Atlanta, GA
9. Moderator, session on “OBESITY, METABOLISM, NUTRITION AND HEALTH DISPARITIES”, 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
10. Co-Chair and Speaker (two presentations), Leiomyomata, clinical updates, Research Development, and disparities in disease, outcomes, and access to care. postgraduate course, 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
11. Co-Moderator and speaker, Health Disparity Interactive session debate “Biological, Social, and Environmental Disparities in Reproduction” . 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
12. Speaker and Moderator, Roundtable Luncheon “Novel Approaches for Prevention of Uterine Fibroids”, 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
13. Chair & Moderator, Fibroid lunchtime symposium “Novel Molecular Targets for Medical Treatment of Uterine Fibroids” 60th Annual meeting, Society of Gynecologic Investigation (SGI), , March 20-23, 2013.
14. Co-Chair, 24th Annual W. F. B. James Symposium & 9th Annual Research Symposium, Meharry Medical College, Thursday, April 19, 2012, S. S. Kresge Learning Resource Center, Lecture Hall 3 & 4, Nashville, Tennessee.
15. Moderator, session on “Reproductive Immunology & Aging”, Society of Gynecologic Investigation (SGI), San Diego, March 21-24, 2012.
16. Co-Chair and Speaker (three presentations), Advances in Uterine Fibroids, Postgraduate course, 67th annual meeting, American Society of Reproductive Medicine (ASRM), Orlando, Florida, 15-19, 2011.
17. Chair and Moderator, Interactive session debate “Myomectomy & IVF” , 67th annual meeting, American Society of Reproductive Medicine (ASRM), Orlando Florida, Oct 15-19th, 2011.
18. Moderator, First Prize Oral abstract presentations, 67th annual meeting, American Society of Reproductive Medicine (ASRM), Orlando Florida, Oct 15-19th, 2011.
19. Moderator, Panel on Uterine Fibroids. American Gynecologist and Obstetrician Society (AGOS), Chicago, Sept 14-17, 2011.
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20. Chairman, Session on Regenerative Medicine/Structural Biology, 3rd International Conference on Drug Discovery & Therapy, February 7-10, 2011, Dubai Women’s College, Dubai, UAE.
21. Co-Chair, Concurrent Session 7: Reproductive Health. 12th RCMI International symposium on health disparity, December 6-9, 2010, Nashville, Tennessee.
22. Member, Planning committee, 12th RCMI International symposium on health disparity, December 6-9, 2010, Nashville, Tennessee.
23. Chair, Session D: Developing New Model Systems, Advances in Uterine Leiomyoma Research: 3rd NIH International Congress, National Institutes of Health, November 22-23, 2010
24. Chair and Moderator, Interactive session debate “To operate or not to operate on the infertile fibroid patient?”, 66th annual meeting, American Society of Reproductive Medicine (ASRM), Denver, Colorado, Oct 23-27th, 2010.
25. Speaker and Moderator, Roundtable Luncheon “Medical Treatment of Uterine Fibroids?”, 66th annual meeting, American Society of Reproductive Medicine (ASRM), Denver, Colorado, Oct 23-27th, 2010.
26. Co-Chair, Fibroid special interest group oral abstract session, 66th annual meeting, American Society of Reproductive Medicine (ASRM), Denver, Colorado, Oct 23-27th, 2010.
27. Moderator, Pediatric and Adolescent Gynecology Research Think Tank Panel meeting, NIH, May 27-28, 2010
28. Speaker and Moderator, Roundtable Luncheon “Why are Fibroids more common in African Americans?”, 65th annual meeting, American Society of Reproductive Medicine (ASRM), Atlanta, Georgia, Oct 17-21st, 2009.
29. Research Co-Chair, 20th annual W.F.B. James symposium and 5th Annual Research symposium in Obstetrics and Gynecology, Meharry Medical College, Nashville, Tennessee. April 3-5, 2008.
30. Chairman, plenary session, 4th international Obstetrics and Gynecology conference, Assuit University, Egypt, February 15-17 , 2005.
31. Chairman, plenary session, 2nd international Obstetrics and Gynecology conference, Al-Menia University, Egypt, March 3-4, 2004.
Ph.D. THESIS:
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Al-Hendy A, Lipopolysaccharide of Yersinia enterocolitica O:3; Molecular Genetics and Role in Virulence. Turku, Finland: Department of Medical Microbiology, Turku University, 112p., ISBN 951-880-752-3, ISSN 0355-9483, 1992. Thesis.
BIBLIOGRAPHY:
(A) ARTICLES/BOOK CHAPTERS and OTHER PEER REVIEWED PUBLICATIONS: 1. Al-Hendy A, Toivanen P, Skurnik M. Expression cloning of Yersina enterocolitica 0:3
rfb region in Escherichia coli K-12, Microbial Pathogenesis, 1991,10:47-59.
2. Al-Hendy A , Toivanen P, Skurnik M. The effect of growth temperature on thebiosynthesis of Yersinia enterocolitica 0:3 lipopolysaccharide. Temperature regulatesthe transcription of the rfb but not of the rfa region. Microbial Pathogenesis, 1991, 10:88-91.
3. Al -Hendy A , Toivanen P, Skurnik M. Rapid method for isolation and staining ofbacterial lipopolysaccharide. Microbiol Immunol, 1991, 35:331-334.
4. Al-Hendy A , Toivanen P, Skurnik M. Molecular cloning of Yersinia enterocolitica 0:3rfb region. Evidence that temperature regulates the rfb region at the transcriptionallevel. In: Une T, Maruyama T, Tsubokura M (eds): Current Investigation of the Microbiology of Yersiniae. Contrib Microbial Immunol, Basel, Karger, 1991, Vol 12, pp 203-209.
5. Al-Hendy A , Toivanen P, Skurnik M. Lipopolysaccharide O side chain of Yersinia enterocolitica 0:3 is an essential virulence factor in orally infected murine model. Infection and Immunity, 1992, 60:870-875.
6. Zhang L, Al-Hendy A , Toivanen P, Skurnik M. Genetic organization and sequence ofthe rfb gene cluster of Yersinia enterocolitica serotype 0:3: Similarities to the dTDP-L-rhamnose biosynthesis pathway of salmonella and to the bacterial polysacchariede transport systems. Mol Microbiology, 1993, 9:309-321.
7. Skurnik M, Venho R, Zhang L, Toivanen P, Al-Hendy A . Yersinia enterocolitica
serotype 0:3 specific bacteriophage selects lipopolysaccharide core-deficient mutants still expressing O-side chain. Mol Microbiology, 1995, 17:575-594.
8. Al-Hendy A , Hortelano G, Tannenbaum G, Chang P. Correction of the growth defect in dwarf mice by encapsulated non-autologous myoblasts. Human Gene Therapy, 1995, 6:165-175.
9. Al-Hendy A , Hortelano G, Tannenbaum G, Chang P. Growth retardation and acute IGF-I deficiency – Unexpected outcome of growth hormone somatic gene therapy. Human Gene Therapy, 1996, 7:61-70.
10. Hortelano G, Al-Hendy A , Ofosu F., Chang P. Delivery of human factor IX in
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mice by encapsulated recombinant myoblasts: A novel approach towards allogeneic gene therapy of hemophilia B. Blood, 1996, 87:5095-5103.
11. Al-Hendy A , Auersperg N. Applying adenovirus-mediated thymidine kinase/ganciclovir system to ovarian cancer. An efficient in vitro drug sensitization approach. Gynecol Obst Investigation, 1997, 43:268-275.
12. Al-Hendy A , Gene therapy of epithelial ovarian cancer using adenoviral vectors. Prim Care Update Ob Gyn, 1998, 5:158.
13. Ismail N, Hortelano G, Al-Hendy A . Growth hormone gene therapy using encapsulated myoblasts. In cell encapsulation and therapeutics, Eds. Kuhtreber WM., Lanza RP, Birkhauser, Boston, Massachusetts, 1999, ISBN 0-8176-4010-X (WWW.birkhauser.com).
14. Al-Hendy A . Enriching research culture in residency. Am J Obstet Gynecol, 1999, 181:1271.
16. Al-Hendy A , Magliocco A, Al-Trewegeri T, Barileanu G, Crelin N, Li H, Strong T,Curiel D, Chedrese J. Ovarian cancer gene therapy: repeated treatment with thymidine kinase in an adenovirus vector and ganciclovir improves survival in a novel immunocompetent murine model. Am J Obstet Gynecol, 2000 March, 182:553-559.
17. Al-Hendy A, Moshynska O, Saxena A, Feyles V. Association between mutations of the follicle-stimulating-hormone receptor and repeated twinning. Lancet, 2000 Sept.9; 356(9233): 914.
18. Al-Hendy A , Moshynska O, Saxena A, Feyles V. Follicle-stimulating-hormone receptor and twinning. Lancet, 2001 January 20; 357(9251):231.
19. Young S, Al-Hendy A , Copland J. Potential Non-hormonal Therapeutics for medical treatment of leiomyomas. In Uterine leiomyoma: Options and Choices; Editor Bruce R. Carr, Seminars in Reproductive Medicine, 2004, 22(2):121-130.
20. Al-Hendy A , Lee E.J, Wang HQ, Eyzaguirre E, Copland JA. Gene therapy of uterine fibroids: adneovirus-mediated express of dominant negative estrogen receptor inhibits turmor growth in nude mice. Am J Obstet Gynecol, 2004. November 191 (5):1621-1631.
21. Walker CL and Stewart EA. Uterine Fibroids: The elephant in the room. Science 2005 June,5728(308): 1589-1592. (Al-Hendy A. Contributed histological photos to this review).
22. Al-Hendy A and Salama A. Salama. Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups. J Soc Gynecol Invest 2006. Feb;13(2): 136-144.
23. Al-Hendy A . and Salama S. Gene therapy and uterine leiomyoma: a review. Human Reproduction updates, 2006 July-Aug;12(4) 385-400.
24. Salama S., Shu-Leong Ho, Hui Q. Wang, Jukka Tenhunen, Carola Tilgmann, and Al-Hendy A. Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas Fertility & Sterility, 2006, July;86(1): 259-262.
25. Al-Hendy A , Salama S. Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans. Fertility & Sterility, 2006, 86: 686-693.
26. Al-Hendy A , Wang H, Copland J. Estrogen and progesterone receptors expression in the endocervix. Implications for hormone replacement therapy after subtotal hysterectomy. Middle East Fertility Society J 2006, 11 (3): 216-221.
27. Salama Salama, Abdelhakim Ben Nasr, Raghvendra K. Dubey,and Al-Hendy A. Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: A potential medicinal treatment for uterine fibroids. J Soc of Gynecol Investig 2006 Dec, 13 (8): 542-50.
28. Melissa J. Wentz, Mohamed Jamaluddin, Robert Garfield and Ayman Al-Hendy.. Regulation of catechol-O-methyltransferase expression in human myometrial cells. Obstetrics & Gynecology 2006 Dec;108(6):1439-47
29. William W. Au, Salama Abdou-Salama, Carlos H. Sierra-Torres, Ayman Al-Hendy Environmental risk factors for prevention and molecular intervention of cervical cancer. Int J Hyg Environ Health. 2007 Dec; 210 (6): 671-8.
30. Salama S, Kamel M, Christman G, Wang H and Al-Hendy A. Gene Therapy of Uterine Fibroids: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells in vitro and in nude mice. Obstetrics Gynecologic Investigations 2007, 63 (2): 61-70.
31. William W. Au, Salama Abdou-Salama, Al-Hendy, A. Inhibition of growth of cervical cancer cells using a dominant negative estrogen receptor gene. Gynecologic Oncology 2007 Feb; 104(2): 276-80.
32. Lu Fang, Monica Longo, Esther Tamayo, William Maner, Ayman Al-Hendy, Garland D. Anderson, Gary D. V. Hankins, George R. Saade. The Effect of Over-expression of sFlt-1 on Blood Pressure, and the Occurrence of Other Manifestations of Preeclampsia, in Unrestrained Conscious Pregnant Mice. Am J Obstet Gynecol 2007 Apr;196(4):396.e1-7;
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33. Essam R. Othman, salama S, Ismail N, and Ayman Al-Hendy. Toward gene therapy of endometriosis: adenovirus-mediated delivery of dominant negative estrogen receptor genes inhibits cell proliferation, reduces cytokine production, and induces apoptosis of endometriotic cells. Fertility & Sterility 2007 Aug; 88(2): 462-71.
34. Kamel M, Salama S, Samira Saleh, Abdel-Moneim M. Osman, Mohamed M. Sayed-Ahmed, and Al-Hendy A . Reversal of doxorubicin resistance by adenovirus-mediated transfer of cyclooxygenase-2 antisense in multidrug-resistant MCF-7 cells. Cancer Therapy. 2007(5)1-10
35. Salih S, Xu X, Veenstra TD, Duleba AJ, Fouad H, Nagamani M, Al-Hendy A. Lower levels of urinary 2-hydroxyestrogens in polycystic ovary syndrome. J Clin Endocrinol Metab. 2007 Aug;92(8):3285-91.
36. Saed G, Al-Hendy A. Salama S, and Diamond M. Gene therapy of peritoneal adhesions: Adenovirus expressing COXII-antisense induce apoptosis in adhesion but not in normal peritoneal fibroblasts. Fertility & Sterility 2008 May:89 (5 Suppl): 1455-60, July 9; (Epub ahead of print)
37. Salama S., Mohammad Jamaluddin, Raj Kumar, Memy H. Hassan and Ayman Al-Hendy . Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: Distinct effect of progesterone receptor isoforms. J Steroid Biochemistry Mol Biol 2007 Nov-Dec, 107 (3-5): 253-61
38. Sana Salih, Mohammad Jamaluddin, Salama A. Salama, Amin Fadel, Manubai Nagamani and Ayman Al-Hendy. Regulation of Catechol-O-Methyl Transferase Expression in Granulosa Cells: A Unifying Model for Follicular Atresia in Polycystic Ovary Syndrome. Fertility & Sterility 2007 July 3; 89(5) 1414-1421
39. Hassan MH, Salama SA, Arafa HM, Hamada FM, Al-Hendy A. Adenovirus-mediated delivery of a dominant-negative estrogen receptor gene in uterine leiomyoma cells abrogates estrogen- and progesterone-regulated gene expression. J Clin Endocrinol Metab. 2007 Oct;92(10):3949-57.
40. Melissa J. Wentz, Leili Shi, Shao-Qing Shi, Salama A. Salama, Harirah HM, Fouad H, Robert E Garfield and Ayman Al-Hendy . Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats. Reproduction 2007 Dec, 134 (6): 831-9.
41. Essam El-Din R. Othman, Daniela Hornung, Hosam T. Salem, Essam A. Khalifa Tarek H. El-Metwally and Ayman Al-Hendy. Serum cytokines as potential bio-markers for non-surgical prediction of endometriosis. Eur J Ob Gyn Reprod Biol 2008 Apr; 137(2):240-6
42. Sana M Salih, Salama A Salama, Mohammad Jamaluddin, Amin A. Fadl, Manubai Nagamani, and Al-Hendy A. Progesterone-mediated regulation of Catechol-O-
43. Zhang Dong, Zoma Willie, Fouad Hala, Salama Salama, and Ayman Al-Hendy. Expression of Stem & Germ Cells Markers within Non-Follicle Structures in Ovaries from Adult Mice. Reproductive Sciences 2008 Feb; 15(2): 139-146.
44. Ghadami M, Salama SA, Khatoon N, Chilvers R, Nagamani M, Chedrese PJ, Al-Hendy A. . Toward gene therapy of primary ovarian failure: adenovirus expressing human FSH receptor corrects the Finnish C566T mutation. Mol Human Reproduction 2008 Jan; 14(1) 9-15.
45. Hassan M, Khatoon, N. Curiel DT, Hamada FM, Arafa HM, Al-Hendy A. Toward gene therapy of uterine fibroids: targeting modified adenovirus to human leiomyoma cells Human Reproduction 2008 March; 23 (3):514-24.
46. Samar Azab SS, , Salama SA, Hassan MH, Khalifa AE, El-Demerdash E, Fouad H, Al-Hendy A, Abdel-Naim AB. 2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft. Cancer Chemotherapy & Pharmacology 2008 Oct;62(5):893-902.
47. Essam Othman, Ayman Al-Hendy . Molecular genetics racial disparities of uterine leiomyomas. Best Pract Res Clin Obstet Gynaecol. 2008 Aug; 22(4):589-601
48. Hassan M. Eduardo Eyzaguirre, MD; Hossam M Arafa, Farid M Hamada, Salama A Salama, and Al-Hendy A. Memy I: a novel murine model for uterine leiomyoma using adenovirus-enhanced human fibroid explants in severe combined immune deficiency mice. Am J Obstet Gynecol 2008 Aug; 199(2): 156.e1-8.
49. Xu X, Othman Eel-D, Hornung D., Al-Hendy A., and Veenstra TD. Multiplexed quantitation of endogenous estrogens and estrogen metabolites in human peritoneal fluid. Electrophoresis 2008 Jun;29(12):2706-13.
50. Salama SA, Kamel M, Awad M, Nasser AH, Al-Hendy A, Botting S, Arrastia C. Catecholestrogens induce oxidative stress and malignant transformation in human endometrial glandular cells: Protective effect of catechol-O-methyltransferase. International J Cancer, 2008 Sep 15;123(6):1246-1254.
51. Essam El-Din R. Othman, David T Curiel, Nilufar Khatoon, Hosam T Salem, Essam A Khalifa, Ayman Al-Hendy. Towards gene therapy of endometriosis: Transductional and transcriptional targeting of adenoviral vectors to endometriosis cells. Am J Obstet Gynecol 2008 Aug;199(2):117.e1-6.
52. Essam Othman, Daniela Hornung, Ayman Al-Hendy. Biomarkers of Endometriosis. Expert Opinion on Medical Diagnostics. 2008 July; 2(7): 741-752. (doi: 10.1517/17530059.2.7.741)
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53. Moon Y. Heo, Salama A. Salama, Nulifar Khatoon, Ayman Al-Hendy, William W. Au. Abrogation of estrogen receptor signaling augments cytotoxicity of anticancer drugs on CaSki cervical cancer cells. Anticancer Research, 2008 July-August; 28(4B): 2181-7.
54. Sana M Salih, Salama A Salama, Amin A. Fadl, Manubai Nagamani and Ayman Al-Hendy. Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma. Fertility & Sterility 2008 Sept. 90(3): 789-797.
55. Azab SS, Salama SA, Abdel-Naim AB, Khalifa AE, El-Demerdash E, Al-Hendy A. 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells? Breast Cancer Research & Treatment 2009 Jan;113(1):9-19.
56. Memy H Hassan, Salama A Salama, Dong Zhang, Hossam M Arafa, Farid M Hamada, Hala Faoud, Cheryl C Walker, Ayman Al-Hendy, Gene therapy targeting Leiomyoma: Adenovirus mediated delivery of dominant negative estrogen receptor gene shrinks uterine tumors in Eker rat model. Fertility and Sterility 2009 Jan 8. [Epub ahead of print]
57. Al-Hendy A . and Salama S. Gene Therapy in Gynecology, in Reproductive Endocrinology: A Molecular Approach, P.J. Chedrese, editor. 2009, pp450. Springer. ISBN 978-0-387-88185
58.Hassan M, Salama S, Walker C and Al-Hendy A. Gene Therapy of Uterine Fibroids: HSV Thymidine kinase/Ganciclovir treatment shrinks uterine leiomyoma lesions in Eker rat. Obstetrics Gynecologic Investigations 2009 March 27 27;68 (1):19-32.
59. Memy Hassan, Essam Othman, Hornung D and Ayman Al-Hendy. Gene Therapy of Benign Gynecological diseases. Advances in Drug Delivery Reviews 2009 May 13 [Epub ahead of print]
60. Hussein M Atta, Mahmoud A El-Rehany, Mieke Dewerchin, Salama R Abdel Raheim, Hend Abdel Ghany, Rasha Fouad, Ayman Al-Hendy Adenovirus-mediated Overexpression of Human Tissue Plasminogen Activator Prevents Peritoneal Adhesion Formation/Reformation in Rats. Surgery 2009 July; 148 (1): 12-17.
61. Hassan Harirah, Chandrasekhar Thota, Melissa J. Wenta, Wahiduz Zaman and Ayman Al-Hendy. Elevated Expression of Catechol-O-methyltrasferase is associated with active labor and increased PGE2 production by human fetal membranes. Am J Obstetrics and Gynecology 2009; 201:496.e1-7.
62. Samar Azab SS, El-Demerdash E, and Al-Hendy A. Multi-drug resistance as Problem challenging Breast Cancer Chemotherapy. In “Breast Cancer: Causes,
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Diagnosis, and Treatment”, Frank Columbus, PhD, Editor-in-Chief, Nova Science Publishers, Inc. (In Press).
63. Atta HM, Al-Hendy A, Salama SA, Shaker OG, Hammam OA. Low-dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation. Liver Int. 2009 Jun 3. [Epub ahead of print]
64. Dong Zhang, Mohamed Al-Hendy, Gloria Richard-Davis, Valerie Montgomery-Rice, Veera Rajaratnam, Ayman Al-Hendy. Green Tea Extract Inhibits Human Leiomyoma Cell Proliferation via Multiple Signaling Pathways. Fertility and Sterility 2009, doi:10.1016/j.
65. Dong Zhang, Mohamed Al-Hendy, Gloria Richard-Davis, Valerie Montgomery-Rice, Chakradhari Sharan, Veera Rajaratnam, Anjali Khurana, Ayman Al-Hendy. Green Tea Extract inhibits Proliferation of Uterine Leiomyoma Cells In vitro and In vivo. American Journal of Obstetrics and Gynecology 2010 March; 202(3): 289e1-289e9.
66. Mohsen Ghadami, Ebtehal El-Demerdash, Awadh A. Binhazim, Anthony E. Archibong, Xinlei Chen, Billy R. Ballard, M. Ram Sairam, Ayman Al-Hendy.
Toward Gene Therapy of Premature Ovarian Failure: Intraovarian Injection of Adenovirus Expressing Human FSH receptor Restores Folliculogenesis in FSHR (-/-) FORKO Mice. Molecular Human Reproduction 2010; 16(4):241-250.
67. Sunil Halder, Sharan Chakrabarty , Ayman Al-Hendy. Vitamin D3 Induces Apoptosis in Human Leiomyoma Cells via down regulation of Catechol-O-Methyl Transferase. Fertility and Sterility 2011 Apr;96(4):E754-62.
68. Sunil Halder, and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Reduces TGF β3-Induced Fibrosis-Related Gene Expressions in Human Uterine Leiomyoma Cells. Journal of Clinical Endocrinology and Metabolism 2011 Jan;95(1):247-53.
69. Vargis, E., Webb, C.N., Paria, B.C., Bennett, K.A., Reese, J , Al-Hendy, A., Mahadevan-Jansen, A. Detecting changes during pregnancy with Raman spectroscopy, Proceedings of the 2011 Biomedical Sciences and Engineering Conference: Image Informatics and Analytics in Biomedicine, BSEC 2011, 2011. Proceedings of the 2011 Biomedical Sciences and Engineering Conference: Image Informatics and Analytics in Biomedicine, BSEC 2011, Article number 587232, http://www.scopus.com/record/display.url?eid=2-s2.0-79959901322&origin=inward&txGid=F3_lzBQvPTZNAUo2D9MmO3K%3a19
70. Vargis, E., Webb, C.N., Paria, B.C., Bennett, K.A., Reese, J , Al-Hendy, A., Mahadevan-Jansen, A. Using Raman spectroscopy to study the onset of labor: A pilot study. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 7890, 2011Progress in Biomedical Optics and Imaging - Proceedings of SPIE Volume 7890, 2011, Article number 789019 http://www.scopus.com/record/display.url?eid=2-s2.0-79955449523&origin=inward&txGid=F3_lzBQvPTZNAUo2D9MmO3K%3a43
71. Sangeeta Nair and Ayman Al-Hendy. Adipocytes Enhance the Proliferation of Human Leiomyoma Cells Via TNFα Proinflammatory Cytokine. Reproductive Sciences (In Press)
72. Chandrasekhar Thota, Ramkumar Menon, Stephen Fortunato, and Ayman Al-Hendy. A single nucleotide polymorphism in fetal COMT gene is associated with preterm birth in African Americans. Reproductive Sciences (In Press)
73. Samar Azab and Ayman Al-Hendy. Signal Transduction Pathways in Breast cancer: Drug Targets and Challenges. In “Breast Cancer Cells”; EDITOR: Mehmet Gunduz. , (2011) ISBN 979-953-307-137-3. http://www.intechopen.com/articles/show/title/signal-transduction-pathways-in-breast-cancer-drug-targets-and-challenges
74. Hassan MH, Fouad H , Bahashwan S and Al-Hendy A. Towards nonsurgical therapy for Uterine Fibroids: Catechol-O-Methyl Transferase Inhibitors Shrinks Uterine Fibroid Lesions in the Eker Rat Model. Human Reproduction (In Press)
76. Mohamed S. Abdelraheem and Ayman Al-Hendy. Innovative Oral Treatment of Uterine Fibroids. Obstetrics Gynecology International 2012:943635. Epub 2012 Feb 16. http://www.hindawi.com/journals/ogi/aip/943635/
77. Mohamed S. Abdelraheem and Ayman Al-Hendy. Medical Treatment of Uterine Fibroids. Reproductive Sciences Apr;19(4):339-53. doi: 10.1177/1933719111432867. Epub 2012 Feb 28. PMID: 2237886[PubMed - indexed for MEDLINE]
78. Mohamed Sabry, Abdou S Ait Allah , Eman Roshdy, Ayman Al-Hendy. Laparoscopic Management of a Torted Large Ovarian Cyst in a Virgin Adolescent Patient: A Case Report. International J Women Health (In Press) http://www.dovepress.com/articles.php?article_id=9910
79. Sunil K. Halder, Chakradhari Sharan, Kevin G. Osteen, and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Treatment Shrinks Uterine Leiomyoma Tumors in Eker Rat Model. Biology of Reproduction (In Press)
80. Mohsen Ghadami, Ebtehal El-Demerdash, Dong Zhang , Salama A. Salama , Awadh A. Binhazim , Anthony E. Archibong , Xinlei Chen , Billy R. Ballard , M. Ram Sairam , Ayman Al-Hendy. Bone marrow transplantation restores ovarian
folliculogenesis and steroid hormones production in primary ovarian failure. Plos One (In Press)
81. Sangeeta Nair, Robyn Tamboli , Pamela.A.Marks, Naji Abumrad and Ayman Al-Hendy. Weight loss after bariatric surgery is associated with increased level of urinary 2 hydroxy estradiol. Mol Cell Endocrinology (In Press)
82. Elizabeth Vargis, Naoko Brown, Kent Williams, Ayman Al-Hendy, Bibhash C. Paria, Jeff Reese, Anita Mahadevan-Jansen. Detecting Biochemical Changes in the Rodent Cervix During Pregnancy Using Raman Spectroscopy (2012). Annals of Biomedical Engineering Doi: 10.1007/s10439-012-0541-4.
83. Mohamed S. Abdelraheem and Ayman Al-Hendy. Medical Treatment of Uterine Fibroids to Decrease rate of hysterectomy (2012). In “Hysterectomy, an update”, Al-Hendy, Editor, Intech publishers, ISBN 978-953-51-0434-6.
84. Kiffany J Peggs, HoVan Nguyen, Diba Enayat, Nancy R Keller, Italo Biaggioni, Bonnie K Black, David Robertson, Ayman Al-Hendy, and Satish R Raj.
Gynecological Abnormalities and Catamenial Lightheadedness in Postural Tachycardia Syndrome: Possible Role of Estrogen. International J Gynecology Obstetrics 2012 Jun 19. [Epub ahead of print].
85. Chandrasekhar Thota, Ramkumar Menon, Stephen Fortunato, and Ayman Al-Hendy. Vitamin D Elicits Anti-inflammatory Response inhibits contractile-associated proteins and modulates Toll-like receptors in Human Myometrial Cells". Reproductive Sciences (In Press)
86. Nesreen Ali, Eman Roshdy, Mohamed Sabry, Ayman Al-Hendy. Green Tea: Varieties, Production and Health Benefits. In “Green Tea & Health”, Professor Wenbiao Wu, Editor. Nova Science publishers, Inc. 2013, PP: 33-73. ISBN: 978-1-62257-562-6.
87. Mohamed Sabry and Ayman Al-Hendy. Racial Diversity and Uterine Leiomyoma. In Race & Reproduction, Fady Sharara Ed. (In Press).
88. M. Abdelraheem, H. Sunil, A. Al-Hendy. Lower Serum Vitamin D Levels Correlate with increased risk of Uterine Leiomyoma. International J Women Health 2013;5:93-100. doi: 10.2147/IJWH.S38800. Epub 2013 Feb 27. PMID: 23467803 [PubMed]
89. Gangula PR, Dong YL, Al-Hendy A, Richard-Davis G, Montgomery-Rice V, Haddad G, Millis R, Nicholas SB, Moseberry D. Protective cardiovascular and renal actions of vitamin D and estrogen Front Biosci (Schol Ed). 2013 Jan 1;S5:134-148.
90. Joshua Younger, K. Maravet Baig-Ward, James H Segars, Ayman Al-Hendy. Clinical Spectrum of Fibroid Disease. In Gynecology In Practice (Fibroid), James
H. Segars, Editor. Wiley-Blackwell publishers, Inc. 2013, PP: 11-23. ISBN: 978-0-470-67094-1.
91. William H. Catherino, MD, Heba M. Eltoukhi, Ayman Al-Hendy. Racial and Ethnic Differences in the Pathogenesis and Clinical Manifestations of Uterine Leiomyoma. Semin Reprod Med 2013;31:370–379
92. K Ravella, A Al-Hendy, C Sharan, AB Hale, KM Channon, S. Srinivasan, PR
Gangula. Chronic estrogen deficiency Causes Gastroparesis by Altering Neuronal Nitric Oxide Synthase Function. Digestive Diseases and Sciences (In Press)
93. Sangeeta Nair, David T Curiel and Ayman Al-Hendy. Targeting adenoviral vector for enhanced gene therapy of uterine leiomyomas. Human Reproduction (In Press)
94. Chandrasekhar Thota, Ramkumar Menon, Stephen Fortunato, and Ayman Al-Hendy. Hypovitaminosis D is a novel risk factor for preterm labor. Reproductive Sciences (In Press)
95. Sunil K. Halder, Chakradhari Sharan, Kevin G. Osteen, and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Treatment inhibits MMPs & TIMP in human Leiomyoma cells. Human Reproduction 2013 Sep;28(9):2407-16. doi:10.1093/humrep/det265. Epub 2013 Jun 27. PMID: 23814095 [PubMed - in process] Related citations
96. King, Nicole, Al-Hendy , Ayman, Diamond, Michael, Abu-Soud, Husam and Saed, Ghassan. Uterine Fibroids are Characterized by an Impaired Antioxidant Cellular System: Potential Role of Hypoxia in the Pathophysiology of Uterine Fibroids. Journal of Assisted Reproduction and Genetics 2013, Jul 30(7):969-74
97. Eman Roshdy, Veera Rajaratnam, Sarbani Maitra, Mohamed Sabry, Abdo S Ait Allah, Ayman Al-Hendy. Treatment of Symptomatic Uterine Fibroids with Green Tea Extract: A Randomized Controlled Clinical Trial. International J Women Health 2013;5:477-86. doi: 10.2147/IJWH.S41021. PMID: 23950663 [PubMed]
98. Sangeeta Nair, Ghassan M. Saed, Hussein M. Atta, Michael P. Diamond, David T. Curiel and Ayman Al-Hendy. Towards Gene Therapy of Postoperative Adhesions: Fiber and Transcriptional Modifications Enhance Adenovirus Targeting Towards Human Peritoneal Adhesion Cells. Gynecologic Obstetric Investigations 2013;76(2):119-24. doi: 10.1159/000353426. Epub 2013 Aug 6. PMID: 23920223 [PubMed - in process]
99. Chandrasekhar Thota, Archana Laknaur, Takeisha Farmer, Ayman Al-Hendy and Nahed Ismail. Vitamin D Reverses THP1 Monocyte induced contractile Profile in Human Uterine Smooth Muscle Cells. Am J Obstetrics Gynecology 2013 Nov 18. doi:pii: S0002-9378(13)02039-5. 10.1016/j.ajog.2013.11.027. [Epub ahead of print] PMID: 24262718 [PubMed - as supplied by publisher]
100. Sunil K. Halder, Chakradhari Sharan, Kevin G. Osteen, and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Treatment reduces extracellular matrix-associated protein expression in human uterine fibroid cells. Biology of Reproduction 2013 Oct 30. [Epub ahead of print] PMID: 24174578 [PubMed - as supplied by publisher
101. Sangeeta Nair, Salama Salama and Ayman Al-Hendy. Obesity & the Endometrium : Adipocyte-secreted Proinflammatory TNFα Cytokine Enhances the Proliferation of Human Endometrial Glandular Cells. Obstetrics Gynecology International 2013:368543. Epub 2013 Oct 30. PMID: 24288542 [PubMed - as supplied by publisher]
102. King, Nicole, Al-Hendy , Ayman , Diamond, Michael, Abu-Soud, Husam and Saed, Ghassan. Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma. Reproductive Sciences 2014 Feb 11.
103. Foster TL, Laknaur A, Hood D, Al-Hendy A, Thota C. Effects of Benzo(a)pyrene During Pregnancy. Obstet Gynecol 2014 May; 123 1:50 doi: 10.1097/01.AOG.0000447339.03689.59.
104. Dong Zhang, Veera Rajaratnam, Omar Al-Hendy, Ayman Al-Hendy. Green Tea Extract Inhibition of Human Leiomyoma Cells Proliferation is Mediated via Catechol-O-Methyltransferase. Obstetrics Gynecologic Investigations. In Press
105. Dalia Moghazy, Omar Al-Hendy, Ayman Al-Hendy. Krukenberg Tumor Presenting as Back Pain and a Positive Urine Pregnancy Test. Journal of Ovarian Research. In Press
106. Sunil Halder, C Sharan, Ayman Al-Hendy. Paricalcitol, a VDR Activator, Inhibits Tumor Formation in a Murine Model for Uterine Fibroids. Reproductive Sciences. In Press
107. Julie A. W. Stilley, Debora E. Christensen, Kristin B. Dahlem, Rongbin Guan, Ayman Al-Hendy, Patricia A. Kirby, and Deborah L. Segaloff. FSH Receptor (FSHR) in Human Non-Pregnant Extra-gonadal Reproductive Tissues and in Developing Placenta and Potential Roles for FSHR in Pregnancy as Shown in Mice. Biology of Reproduction. In Press
108. Dalia Moghazy, Omar Al-Hendy, C Sharan, Malika Nair, C Rack, Ayman Al-Hendy. Low Malignant Potential Virilizing Leydig-Sertoli Cell Ovarian Tumors after Menopause: Case Report and Review of Literature. Journal of Ovarian Research. In Press
109. Ayman Al-Hendy and Marwa Badr. Can vitamin D reduce the risk of uterine fibroids? Editorial. Women Health. Vol. 10, No. 4, Pages 353-358 (2014).
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110. Hussein Atta, Mahmoud El-Rehany, Olfat Hammam, Hend Abdel-Ghany, Maggie Ramzy, Martin Roderfeld, Elke Roeb, Ayman Al-Hendy, Salama Abdel Raheim,
Hatem Allam, Heba Marey. Mutant MMP-9 is More Effective than HGF Gene Therapy in Reducing Rat Liver Fibrosis through Repression of ASH1 and EZH2 Methyltransferases. PlosOne. In Press
111. Sunil K. Halder, Archana Laknaur, Lawrence C. Layman, Michael Diamond, and Ayman Al-Hendy. Novel MED12 Gene Somatic Mutations in Southern USA women with Symptomatic Uterine Fibroids. Molecular Genetics and Genomics. In Press
112. Mostafa Borahay, Ayman Al-Hendy. Simvastatin Potently Induces Calcium-Dependent Apoptosis of Human Leiomyoma Cells. Journal of Biological Chemistry. In Press
113. Sunil Halder, Ayman Al-Hendy. Effect of Vitamin D treatment on the expression of estrogen receptors and progesterone receptors in human uterine leiomyoma cells. Journal of Clinical Endocrinology and Metabolism. In Press
114. Sara Mohamed, Michael Diamond, C. Thota, Paul Browne, Ayman Al-Hendy. Why Preterm Birth is stubbornly high in African Americans?. Obstetrics Gynecology International Journal. In Press.
115. Chen, Yen-Hao, Wu, Hsiaoli, Chuang, Tung Yueh, Al-Hendy, Ayman, Diamond, Michael, Azziz Ricardo. Berberine inhibits the proliferation of human uterine leiomyoma cells. Fertility & Sterility. In Press
116. Nothnick WB, Al-Hendy A , Lue JR. Circulating microRNAs as diagnostic biomarkers for endometriosis: privation and promise. J Minim Invasive Gynecol. 2015 Mar 7. pii: S1553-4650(15)00262-9. doi: 10.1016/j.jmig.2015.02.021. [Epub ahead of print] PMID: 25757811
117. Laknaur A, Foster TL, Bobb LE, Ramesh A, Ladson GM, Hood DB, Al-Hendy A, Thota C. Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene. J Appl Toxicol. 2015 Sep 11. doi: 10.1002/jat.3216. [Epub ahead of print], PMID: 26358852
118. Mostafa Borahay, Ayman Al-Hendy. Simvastatin Potently Induces Calcium-Dependent Apoptosis of Human Leiomyoma Cells. American Journal of Obstetrics and Gynecology. In Press
119. Qiwei Yang, Aymara Mas Perucho, Michael Diamond, Ayman Al-Hendy. Role of epigenetics in uterine fibroid pathogenesis. Reproductive Sciences. In Press
120. Mostafa A. Borahay, Gokhan S. Kilic, Ayman Al-Hendy and Darren Boehning. Signaling Pathways Driving Uterine Leiomyoma Development and Growth. Molecular Medicine. In Press
121. Aymara Mas Perucho, Sangeeta Nair, Carlos Simon, Michael Diamond, Archana Laknaur, , Ayman Al-Hendy. Isolation and characterization of stem cells from human uterine fibroid lesions, adjacent myometrium and normal myometrium. Fertility and Sterility. In Press
122. Brakta S, Diamond M, Diamond J, Al-Hendy A, Halder S. Role of Vitamin D in Uterine Fibroids. Fertility and Sterility. 2015 Sep;104(3):698-706. doi: 10.1016/j.fertnstert.2015.05.031. Epub 2015 Jun 13. PMID: 26079694. Commentary: Is vitamin D the answer for prevention of uterine fibroids? Wu JL1, Segars JH 2. Fertil Steril. 2015 Sep;104(3):559-60. doi: 10.1016/j.fertnstert. 2015.06.034. Epub 2015 Jul 15, PMID: 26187299 [PubMed - in process]
123. Mohamed Sara, Al-Hendy, Ayman, Chaffin, Joanna, Ghamande, Sharad, Browne, Paul. Atypical presentations of molar pregnancy: Diagnostic role of imaging, β-HCG measurement and P57 immunostaining. J Ultrasound in Medicine. In Press
124. William Howard Parker, Andrew M Kaunitz, Elizabeth A Pritts, David L Olive, Eva Chalas, Daniel Clark-Pearson, Jonathan S. Berek and Leiomyoma Morcellation Study Group). (Ayman Al-Hendy, member, Leiomyoma Morcellation Study Group). The FDA's Guidance Regarding Morcellation of Leiomyomata— Well Intentioned, but is it Harmful for Women?. Obstetrics Gynecology. In Press.
125. Mohamed Baz, Shahinaz Shalaby, Sangeeta Nair, Archana Laknaur, Ayman Al-Hendy. Targeted Adenoviral vector exhibits enhanced tumor shrinkage effects against uterine fibroid lesions in vivo. Reproductive Sciences. 2016 Apr; 23(4):464-74. doi: 10.1177/1933719116630413. Epub 2016 Feb 16. Commentary; In the Spotlight; Maria Rosa Maduro, PhD, Gene Therapy to Fight Uterine Leiomyomas. Reproductive Sciences. 2016, Vol. 23(4) 413-414, 2016, DOI: 10.1177/1933719116633317
126. Essam Othman, Ibraheem Hendy, Ahmad Fetih, Ayman Al-Hendy. Enhancing adenoviral-mediated gene transfer and expression to endometrial cells. Reproductive Sciences. In Press
127. Ayman Al-Hendy, Michael Diamond, Tom Boyer and Sunil Halder. Vitamin D3 Inhibits Wnt/β-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells. Journal of Clinical Endocrinology and Metabolism. 2016 Apr;101(4):1542-51. doi: 10.1210/jc.2015-3555. Epub 2016 Jan 28. PMID: 26820714
128. Qiwei Yang, Michael Diamond, Ayman Al-Hendy. The emerging role of extracellular vesicle-derived miRNAs: implication in cancer progression and stem cell related diseases. Journal of Clinical Epigenetics. In Press
129. Shalaby, Shahinaz; Khater, Mostafa; Mas Perucho, Aymara; Mohamed, Sara; Helwa, Inas; Laknaur, Archana; Lebedyeva, Iryna, Liu, Yutao; Diamond, Michael; Ayman Al-Hendy. Magnetic Nanoparticles enhance suicide gene therapy against human uterine fibroids differentiated and tumor forming stem cells. Fertility and Sterility. In Press
130. Qiwei Yang, Sangeeta Nair, Michael Diamond and Ayman Al-Hendy. The polycomb group protein EZH2 impairs DNA damage repair in human uterine fibroids. Biology of Reproduction. In Press
131. Parker W, Berek JS, Pritts E, Olive D, Kaunitz AM, Chalas E, Clarke-Pearson D, Goff B, Bristow R, Taylor HS, Farias-Eisner R, Fader AN, Maxwell GL, Goodwin SC, Love S, Gibbons WE, Foshag LJ, Leppert PC, Norsigian J, Nager CW, Johnson T, Guzick DS, As-Sanie S, Paulson RJ, Farquhar C, Bradley L, Scheib SA, Bilchik AJ, Rice LW, Dionne C, Jacoby A, Ascher-Walsh C, Kilpatrick SJ, Adamson GD, Siedhoff M, Israel R, Fidela Paraiso M, Frumovitz MM, Lurain JR, Al-Hendy A, Benrubi GI, Raman SS, Kho RM, Anderson TL, Reynolds RK, DeLancey J. An Open Letter to the Food and Drug Administration Regarding the Use of Morcellation Procedures in Women Having Surgery for Presumed Uterine Myomas. J Minim Invasive Gynecol. 2016 Jan 8. pii: S1553-4650(15)01732-X. doi: 10.1016/j.jmig.2015.12.012. [Epub ahead of print] PMID: 26773577
132. Mohamed SA, Al-Hendy A, Ghamande S, Chaffin J, Browne P. Atypical Presentations of Molar Pregnancy: Diagnostic Roles of Imaging, β-Human Chorionic Gonadotropin Measurement, and p57 Immunostaining. J Ultrasound Med. 2016 Feb 9. pii: 15.05027. [Epub ahead of print] PMID: 26860483
133. Qiwei Yang, Michael P Diamond, Ayman Al-Hendy. Early life adverse environmental exposures increases the risk of uterine fibroid development: role of epigenetic regulation. Frontiers in Pharmacology. In Press
134. Essam Rashad Othman, Ahmad Fetih, Al-Hendy Ayman, Ibraheem hendy, Ayat Sayed, Mostafa Husain, Daniela Hornung. Soluble tumor necrosis factor- alpha receptors in the serum of endometriosis patients. European Journal of Obstetrics & Gynecology and Reproductive Biology. In Press
135. Yang, Qiwei; Diamond, Michael; Laknaur, Archana; Stone, Lelyand; Lue, John, and Al-Hendy, Ayman. Identification of polycomb group protein EZH2-mediated DNA mismatch repair gene MSH2 in human uterine fibroids" Reproductive Sciences. In Press
136. Erin Latif, Bunja J. Rungruang, Marwa Badr, Ayman Al-Hendy, Michael P. Diamond, Eran Rotem, Jeremy Cannell, Paul C. Browne. Disseminated intravascular coagulation from prolonged severe placental abruption and fetal demise treated with uterine artery embolization. Journal of Neonatal-Perinatal Medicine. In Press
137. Prusinski L, Al-Hendy A, Yang Q. Developmental exposure to endocrine disrupting chemicals alters the epigenome: Identification of reprogrammed targets. Gynecol Obstet Res. 2016 Jul;3(1):1-6. Epub 2016 May 3. PMID: 27478869
138. Yang Q, Diamond MP, Al-Hendy A (2016) Converting of Myometrial Stem Cells to Tumor-Initiating Cells: Mechanism of Uterine Fibroid Development. Cell Stem Cells Regen Med 2(1): doi http://dx.doi.org/10.16966/2472-6990.e103
139. Sara A. Mohamed, Ayman Al-Hendy, Jay Schulkin, Michael L. Power (2016). Opinions and practice of US-based obstetrician-gynecologists regarding vitamin D screening and supplementation of pregnant women. J of Pregnancy. In Press
140. Essam R. Othman, Dalia A. Elgamal, Abeer M. Alrefaiy, Ibraheem I. Abdelaal, Asmaa F. Abdel-Mola, and Ayman Al-Hendy (2016). Identification and potential role of telocytes in human uterine leiomyoma. Contraception Reproductive Medicine. In Press
141. Tiffany A. Katz, Qiwei Yang, Lindsey S. Treviño, Cheryl L. Walker, Ayman Al-Hendy Endocrine disrupting chemicals and uterine fibroids. Fertility & Sterility. In Press
142. Mas A, Elam L, O’Connor P.M , Yang Q, Kleven DT, Simon C, Walker C.L., Al- Hendy A. Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis. Stem Cells. In Press
143. Hsiao-Li Wu, Tung-Yueh Chuang, Jie Min, Cristina McCrary, Lawrence C. Layman, Ayman Al-Hendy, Michael P. Diamond, Ricardo Azziz, and Yen-Hao Chen. Berberine Inhibits Uterine Leiomyoma Cells Proliferation via Down-Regulation of Cyclooxygenase 2 (COX2) and Pituitary Tumor-Transforming 1 (PTTG1)" Berberine Inhibits the Proliferation of Uterine Leiomyoma Cells in Nude Mice. Reproductive Sciences. In Press
144. Sunil Halder, Ayman Al-Hendy. Hypovitaminosis D and high serum TGFβ3, important biomarkers for uterine fibroids risk . Fertility and Sterility. In Press
145. Atta HM, Al-Hendy AA, Abdel Raheim SR, Abdel-Ghany H, Nasif KA, Abdellah AM, Zenhom NM, Kamel HS. Modified Adenovirus Reduces De Novo Peritoneal Adhesions in Rats and Limits Off-Target Transfection. Role of EZH2 in Adhesion Formation. J Invest Surg. 2016 Oct 3:1-10. PMID: 27690696
146. Sabry M, Hassanin IMA, Ait-Allah AS, Mohamed SM, Helmy YA, Al-Hendy A. Decoding the Proteome of In-Vitro Fertilization Ovarian Follicular Fluid for Women Over 35 Years. J Clin Anal Med 2016; 7(1): 60-4. DOI: 10.4328/JCAM.3417
147. Mostafa A. Borahay, Aymara Mas Perucho, Sara Adams, Ayman Al-Hendy. Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications. Reproductive Sciences. In Press
148. Aymara Mas, Lauren Prusinski, Qiwei Yang, Patricia Diaz-Gimeno, Lelyand Elam, Michael Diamond, Carlos Simon and Ayman Al-Hendy. Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy. Biology of Reproduction. In Press
149. Sunil Halder, Aymara Mas Perucho, Michael Diamond, Nahed Ismail, Ayman Al-
Hendy. Silencing Med12 in human leiomyoma cells abrogates proliferation in vitro and in vivo. Endocrinology. In Press
150. Sara A. Mohamed, Abdelmagid Mashaly, Mohamed Tawfeek,Farha Elchennawi, Ahmad Darwish, Shahinaz Shalaby, AymanAl-Hendy and Paul Browne. Cord Blood Donor Criteria: A Cross-Sectional Study in Augusta. J Gynec Obstet 2017; 1:005.
151. Sara A. Mohamed, Shahinaz M. Shalaby, Mohamed Abdelaziz, Soumia Brakta, William D Hill, Nahed Ismail, Ayman Al-Hendy. Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy Induced Ovarian Failure. Reproductive Sciences. In Press
152. Nicole M Fletcher, Ira Memai , Mohammed S Abusamaan , Mohammed G Saed, Ayman Al-Hendy, Michael P Diamond, and Ghassan M Saed. Oxidative stress: a key regulator of leiomyoma cell survival. Fertility and Sterility. 2017 Jun;107(6):1387-1394.e1. doi: 10.1016/j.fertnstert.2017.04.015. Epub 2017 May 5. PMID: 28483502
153. Qiwei Yang, PhD; Ayman Al-Hendy. Developmental Environmental Exposure Alters the Epigenetic Features of Myometrial Stem Cells. Gynecol Obstet Res Open J. 2016; 3(2): e1-e4. doi: 10.17140/GOROJ-3-e005
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154. Mohamed Baz, Kumar Sharma, Ayman Al-Hendy. Cervical Superficial Myofibroblastoma: Case Report and Review of the Literature. SAGE Open Medical Case Reports. In Press
155. Abdeljabar El Andaloussi, Samar Habib, Gizem Soylemes, Heba Husseini, Ayman Al-Hendy and Nahed Ismail. Defective Expression of ATG4D Abrogates Autophagy and Promote Human Leiomyoma Pathogenesis. Cell Death Discovery (Nature Publishers). In Press
156. Mohamed, Sara A; El Andaloussi, Abdeljabar ; Al-Hendy, Ayman; Menon, Ramkumar; Behnia, Faranak; Schulkin, Jay; Power, Michael L. Vitamin D and corticotropin-releasing hormone in term and preterm birth: potential contributions to preterm labor and birth outcome. J Maternal-Fetal & Neonatal Medicine. In Press
157. Evans Meyer, Ayman Al-Hendy, Elizabeth Stewart. Uterine Fibroids:unmet needs. In Seminars in Reproductive Medicine “Uterine Fibroids”. Editors: Al-Hendy & Segars. In Press.
158. Abdeljabar El Andaloussi, Zuni Chaudhry, Ayman Al-Hendy, Nahed Ismail. Uterine Fibroids: Bridging Genomic Defects and Chronic Inflammation. In Seminars in Reproductive Medicine “Uterine Fibroids”. Editors: Al-Hendy & Segars. In Press.
159. Hoda Elkafas, Yanq Qiwei, and Ayman Al-Hendy. Origin of Uterine Fibroids: Conversion of Myometrial Stem Cells to Tumor Initiating Cells. In Seminars in Reproductive Medicine “Uterine Fibroids”. Editors: Al-Hendy & Segars. In Press.
160. Segars JH, Al-Hendy A. Uterine Leiomyoma: New Perspectives on an Old Disease. Semin Reprod Med. 2017 Nov; 35(6):471-472. doi: 10.1055/s-0037-
1606569. Epub 2017 Nov 3. PMID: 29100233
161. James H. Segars, MD and Ayman Al-Hendy , MD, PhD. Legro RS. Semin Reprod Med. 2017 Nov; 35(6):469-470. doi: 10.1055/s-0037-1607998. Epub 2017 Nov 3. PMID: 29100232
162. Mohamed Ali, Ayman Al-Hendy. Selective Progesterone Receptor Modulators for Fertility Preservation in Women with Symptomatic Uterine Fibroids. Biology of Reproduction. In Press
163. James A. Simon, William Catherino, James H. Segars, MD, Rick E. Blakesley, Anna Chan, PharmD, Vilma Sniukiene, Ayman Al-Hendy. Ulipristal Acetate for Treatment of Symptomatic Uterine Leiomyomas: A Randomized Controlled Trial. Obstetrics Gynecology. In Press
164. Mohamed Ali, Zunir Tayyeb Chaudhry, Ayman Al-Hendy. Successes and Failures of Uterine Leiomyoma Drug Discovery. Expert Opinion on Drug Discovery. In Press
165. Qiwei Yang, Ayman Al-Hendy. The Emerging Role of p27 in Development of Diseases. Cancer Stud Mol Med Open J. 2018; 4(1): e1-e2. doi: 10.17140/CSMMOJ-4-e006
166. Fernung LP, Yang Q, Sakamuro D, Kumari A, Mas A, Al-Hendy A. Endocrine Disruptor Exposure during Development Increases Incidence of Uterine Fibroids by Altering DNA Repair in Myometrial Stem Cells. Biol Reprod. 2018 Apr 24. doi: 10.1093/biolre/ioy097.
167. Habib S, El Andaloussi A, Elmasry K, Handoussa A, Azab M, Elsawey A, Al-Hendy A, Ismail N. PDL-1 blockade prevents T cell exhaustion, inhibits autophagy, and promotes clearance of Leishmania donovani . Infect Immun. 2018 Apr 2. pii: IAI.00019-18. doi: 10.1128/IAI.00019-18. [Epub ahead of print] PMID: 29610255
168. Park MJ, Shen H, Spaeth JM, Tolvanen JH, Failor C, Knudtson JF, McLaughlin J, Halder SK, Yang Q, Bulun SE, Al-Hendy A, Schenken RS, Aaltonen LA, Boyer TG. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. J Biol Chem. 2018 Mar 30;293(13):4870-4882. doi: 10.1074/jbc.RA118.001725. Epub 2018 Feb 13. PMID: 29440396
169. Qiwei Yang, Ayman Al-Hendy. Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids. Fertility and Sterility, in press 2018.
1. M. Abdelraheem, and A. Al-Hendy, Editors. Hysterectomy, an update. WWW.InTechopen.com, 2012, ISBN 978-953-51-0434-6.
2. A. Al-Hendy, and S. Salama, Editors. Leiomyomas: Risk Factors, Clinical Manifestations and Treatment Options. Nova Science Publishers, 2014, ISBN: 978-1-63463-584-4.
3. Sara A. Mohamed, Waseem Khoder and Ayman Al-Hendy. Uterine Fibroids and Endometrial Dysfunction. In Al-Hendy, and Salama, Editors. Leiomyomas: Risk Factors, Clinical Manifestations and Treatment Options. Nova Science Publishers, 2014, ISBN: 978-1-63463-584-4.
4. Heba M. Eltoukhi and Ayman Al-Hendy. Recent Advances in Medical Treatment of Uterine Fibroids. In Al-Hendy, and Salama, Editors. Leiomyomas: Risk Factors, Clinical Manifestations and Treatment Options. Nova Science Publishers, 2014, ISBN: 978-1-63463-584-4.
5. Shahinaz Shalaby and Ayman Al-Hendy. Looking for New Druggable Targets in Uterine Fibroids. In Al-Hendy, and Salama, Editors. Leiomyomas: Risk Factors, Clinical Manifestations and Treatment Options. Nova Science Publishers, 2014, ISBN: 978-1-63463-584-4.
6. Marwa Badr and Ayman Al-Hendy. Gene Therapy Applications in Modern Gynecology and Obstetrics. Editor: Hossam Fadel. IMANA publisher. ISBN: Pending. In Press.
7. Elhusseini H, Lizneva D, Gavrilova–Jordan L, Eziba N, Abdelaziz M, Brakta S, Halder S, Al-Hendy A. Vitamin D and Female Reproduction. In "Vitamin D", EDITORS: Sivakumar Joghi and Thatha Gowder. InTech - Open Science Publishers. ISBN 978-953-51-4789-3. In Press.
1. Hope on the Horizon for Uterine Fibroids, by Ayman Al-Hendy, MD, PhD - June 19, 2016 http://globoandworld.com/hope-on-the-horizon-for-uterine-fibroids/
2. Extinguishing the fireballs. http://magazines.augusta.edu/2015/07/14/extinguishing- the-fireballs/
3. The Fibroid Project (Patient Advocacy group. https://www.youtube.com/watch? v=75b2DsyubpEhttp://www.fibroidsproject.com/about-us/our-team.html
4. A simplified method for removal of wondering Nexplanon implants. Feb 2017.https://www.youtube.com/watch?v=oJZmlgbytsE
(D)ABSTRACTS (OF TOTAL: 228)
1. Al-Hendy A , Toivanen P, Skurnik M. Molecular cloning of rfb region of Yersiniaenterocolitica 0:3. UCLA Symposia Conference on Molecular Biology of Yersiniae, Frisco, Colorado, J Cell Biochem suppl, Feb. 22-27, 1990, 14C:182, Abstracts: CI400.
2. Al-Hendy A , Toivanen P, Skurnik M. Molecular cloning of rfb region of Yersinia enterocolitica O:3. First Congress of International Endotoxin Society, San Diego, California, May 10-12, 1990, Abstracts: I-P-
3. Al-Hendy A , Toivanen P, Skurnik M. Molecular cloning of rfb region of Yersinia enterocolitica O:3. Endotoxin Newsletter, 1990, No. 3, pp:5-6.
4. Al-Hendy A , Toivanen P, Skurnik M. Genetic organization of Yersinia enterocolitica O:3 rfb region. Fifth International Symposium in Yersinia, Mount Fuji, Japan, September 24-26, 1990, Abstracts: 46 (Podium presentation).
5. Al-Hendy A , Toivanen P, Skurnik M. Bacteriophages, old tools for new insights into virulence pathways of Yersinia enterocolitica. Second Scandinavian Meeting of Bacteriology, Turku, Finland, May 15-17, 1991, Abstracts: pp:40.
6. Skurnik M, Al-Hendy A , Tertti R, Toivanen P. Complement activation by Yersinia enterocolitica. Role of YadA and lipopolysaccharide O-side chain. Annual Meeting of Canadian Society of Microbiologists, London, Ontario, Canada, June 2-6, 1991, Abstracts, 53 (Podium presentation).
7. Skurnik M, Al-Hendy A , Tertti R, Toivanen P. Complement activation by Yersinia enterocolitica. Role of YadA and lipopolysaccharide O-side chain. European Federation of Immunological Societies (EFIS), Helsinki, Finland, June 10-12, 1991, Abstracts; 23-12 (Podium presentation).
8. Al-Hendy A , Toivanen P, Skurnik M. A chromosomal locus suppresses the virulence of Yersinia enterocolitica at 37oC. Federation of American Societies for Experimental Biology Summer Conference, Saxtons River, Vermont, July 14-19, 1991.
9. Al-Hendy A , Toivanen P, Skurnik M. Coordinated stage-specific expression of Yersinia virulence. Federation of European Microbiological Societies Symposium, Porvoo, Finland, August 5-7, 1991, Abstracts; 32.
10. Skurnik M, Ismail N, Al-Hendy A , Toivanen P. The Yersinia virulence plasmid encoded adhesin, YadA, is a virulence factor. Federation of European Microbiological Societies (FEMS) Symposium, Porvoo, Finland, August 5-7, 1991,
11. Al-Hendy A , Toivanen P, Skurnik M. A single chromosomal mutation increases virulence of Yersinia enterocolitica by 1000 fold. American Society for Cell Biology/European Molecular Biology Summer Conference, Arolla, Switzerland, August 18-23, 1991, Abstracts; pp: P02.
12. Skurnik M, Al-Hendy A , Toivanen P. A novel locus for in vivo down regulation of Yersinia enterocolitica virulence. American Society for Microbiology General Meeting, New Orleans, Louisiana, May 1992.
13. Al-Hendy A , Hortelano G, Chang P. Allogeneic somatic gene therapy: Correction of growth hormone deficiency in dwarf mice with micro-encapsulated non-autologous myoblasts. 43rd Annual Meeting of the American Society of Human Genetics, New Orleans, Louisiana, Am J Hum Genet October 5-9, 1993, Abstracts: 53:107, (3) Suppl. (Podium Presentation)
14. Al-Hendy A , Hortelano G, Chang P. Unexpected physiological responses of normal mice to a novel form of somatic gene therapy with recombinant growth hormone. Symposium on Growth Factors Interaction During Development, London, Ontario, Canada, October 15-16, 1993, (Podium Presentation), Abstracts:19.
15. Al-Hendy A , Hortelano G, Tannenbaum G, Chang P. Non-autologous somatic gene therapy for the snell dwarf mice. Gene Therapy, New Technologies & Applications, Bethesda, Maryland, April 25-27, 1994, Abstracts: 6.
16. Al-Hendy A , Hortelano G, Tannenbaum G, Chang P. Non-autologous somatic gene therapy for the snell dwarf mice. Cold Spring Harbor Laboratory Meeting on Gene Therapy, September 21-25, 1994.
17. Hortelano G, Al-Hendy A , Ofosu F, Chang P. Delivery of human factor IX in mice by encapsulated recombinant myoblasts: A novel approach towards allogeneic gene therapy of Hemophilia B. 44th Annual Meeting of The American Society of Human Genetics, Montréal, Québec, Canada, October 18-22, 1994.
18. Al-Hendy A , Hortelano G, Tannenbaum G, Chang P. Growth retardation and acute IGF-I deficiency - Unexpected outcome of growth hormone somatic gene therapy. 44th Annual Meeting of the American Society of Human Genetics, Montréal, Ouébec, Canada, October 18-22, 1994, (Podium presentation).
19. Bastedo L, Sands M, Hortelano G, Al-Hendy A , Sly W, Chang P. Partial correction of murine mucopolysaccharidosis VII with micro-encapsulated non-autologous recombinant fibroblasts. 44th Annual Meeting of the American Society of Human Genetics, Montréal, Ouébec, Canada, , October 18-22, 1994.
20. Goyette P, Frosst P, Christensen B, Al-Hendy A , Rosenblatt D, Rozen R. A common mutation resulting in a thermolabile enzyme can be present on the same allele as mutations for sever deficiency of methylenetetrahydrofolate reductase. The Annual
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Meeting of the American Pediatric Society, San Diego, California, May 7-11, 1995.
21. Christensen B, Goyette P, Al-Hendy A , Rosenblatt D, Rozen R. New mutation identified in four unrelated patients with methylenetetrahydrofolate reductase deficiency. The Annual Meeting of the Society of Pediatric Research, May 11-14, 1996.
22. Chang P, Al-Hendy A , Hortelano G, et al. Micro-encapsulated recombinant cells: An alternate approach to gene therapy. Bioartificial Organs-Science and Technology Conference, Nashville, Tennessee, July 21-26, 1996.
23. Al-Hendy A , Auersperg N. Ovarian cancer gene therapy using the adenovirus thymidine kinase/ganciclovir system. An in vitro study. The 1996 Annual Meeting College of Obstetrician and Gynecologists (District VI), Grand Cayman, British West Indies, November 1-3, 1996 (Podium Presentation).
24. Al-Hendy A , Auersperg N. Ovarian cancer gene therapy using the adenovirus thymidine kinase/Ganciclovir system. An in vitro study. University of Saskatchewan, College of Medicine Research Day, Saskatchewan, Canada, January 17, 1997.
25. Al-Hendy A , Magliocco T, El-Tewegeri T, Chedrese J. Saskmouse: A novel murine model for epithelial ovarian cancer. University of Saskatchewan, College of Medicine Research Day, Saskatchewan, Canada, January 17, 1997.
26. Carolina J, Al-Hendy A , Chedrese J. New stable granulosa cell lines. University of Saskatchewan, College of Medicine Research Day, Saskatchewan, Canada, January 17, 1997.
27. Al-Hendy A , Magliocco T, El-Tewegeri T, Chedrese J. Saskmouse: A novel murine model for epithelial ovarian cancer. West Canada Reproductive Biology Meeting, Banff, Canada, February 22-25, 1997.
28. Al-Hendy A , Auersperg N. Ovarian cancer gene therapy using the adenovirus thymidine kinase/ganciclovir system. Society of Obstetricians and Gynaecologists of Canada’s Annual Meeting, Halifax, Nova Scotia, Canada, June 20-25, 1997 (Podium presentation).
29. Al-Hendy A , Magliocco T, El-Tewegeri T, Chedrese J. Saskmouse: A novel murine model for epithelial ovarian cancer. Society of Obstetricians and Gynaecologists of Canada’s Annual Meeting, Halifax, Nova Scotia, Canada, June 20-25, 1997 (Podium presentation).
30. Al-Hendy A , Chedrese, J. Ovarian cancer gene therapy using adenoviral Vectors. Annual Meeting of Canada West Reproductive Biology Society, Saskatoon, Saskatchewan, Canada, February 20-22, 1998 (Podium Presentation).
31. Al-Hendy A. Ovarian cancer gene therapy using adenoviral vsectors. National Students Research Meeting, University of Texas Medical Branch, Galveston, Texas,
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April 11-13, 1998 (Podium Presentation).
32. Al-Hendy A. Gene therapy of epithelial ovarian cancer using adenoviral vectors. American College of Obstetricians and Gynecologists Annual Clinic Meeting, New Orleans, Louisiana, May 11-16 1998 (Podium Presentation).
33. Al-Hendy A , Magliocco T, El-Tewegeri T, Chedrese J. Cytokine gene therapy of epithelial ovarian cancer. American College of Obstetricians and Gynecologists Annual Clinical Meeting, Philadelphia, Pennsylvania, May 15-19, 1999.
34. Al-Hendy A , Tummon I, Termesi L, Martin J. Predictors of pregnancy in donor cycles. Society of Gynaecologists of Canada, Annual Clinical Meeting, Ottawa, Ontario, Canada, June 20-25, 1999 (Accepted for Podium Presentation, Withdrawn).
35. Al-Hendy A , Tummon I, Termesi L, Martin J. Predictors of pregnancy in donor cycles. American College of Obstetricians and Gynecologists District VI Annual Clinical Meeting, Hawaii, October 15-19, 1999 (Podium Presentation).
36. Al-Hendy A , Moshynska O, Saxena A, Olatunbosun F, Feyles A. Prevalence of the Finnish C566T FSH receptor gene mutation in North American women with familial polycystic ovary syndrome. American College of Obstetricians and Gynecologists/American College of Medicine, San Francisco, California, May 16-19, 2000.
37. Al-Hendy A , Moshynska O, Saxena A, Gilliland B, Chedrese J, Feyles A. Familial polycystic ovary syndrome: Candidate mutations in the follistatin gene. The 48th Annual Society for Gynecologic Investigations Meeting, Toronto, Ontario, Canada, J Soc Gyn Invest March 14-17, 2001; 8:92A.
38. Marx S, Garfield R, Saade G, Al-Hendy A.Transgene expression in pregnant rat uterus mediated by an adenovirus expressing -Galactosidase. Seventh Annual Texas Forum on Female Reproduction. Houston, Texas, May 3-4, 2001.
39. Marx S, Garfield R, Saade G, Al-Hendy A . Transgene expression in pregnant rat uterus mediated by an adenovirus expressing -Galactosidase. American Society of Gene Therapy, 4th Annual Meeting, Seattle, Washington, May 30-June 3, 2001.
40. Al-Hendy A , Moshynska O, Chedrese J, Saxena A, Gillilandt B, Feyles V. Familial polycystic ovary syndrome: candidate mutations in the follistatin gene. The 13th International Scientific Congress of the Egyptian Medical Syndicate, Poster #8, p.145, Nasr City, Cairo, Egypt, January 14-17, 2002.
41. Al-Hendy A , Thomas J, Eyzaguirre E. Towards gene therapy in reproduction: In vitro and in vivo gene transfer to human and murine endometrium using adenoviral vectors. 49th Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, California. J Soc Gyn Investigation, March 20-23, 2002, Vol. 9, No.1 (Supplement), No. 289.
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42. Al-Hendy A , Lee E, Eyzaguirre E, Copland J. Towards gene therapy of uterine fibroids: Adenovirus-mediated expression of dominant negative estrogen receptor induces apoptosis in human leiomyoma cells and inhibits tumor growth in nude mice. 49th Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, California (Plenary session), J Soc Gyn Investigation March 20-23, 2002, Vol. 9, No.1 (Supplement), No. 3.
43. Al-Hendy A , Luxon B, Nagamani M. Differential RNA microarray analysis of human myometrium, Uterine Leiomyoma and Uterine Leiomyosarcoma, 49th Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, California, J Soc Gyn Investigation, March 20-23, 2002, Vol. 9, No.1 (Supplement), No. 744.
44. Al-Hendy A , Luxon B. Differential RNA microarray analysis of normal human myometrium, small and large leiomyoma. 49th Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, California, J Soc Gyn Investigation, March 20-23, 2002, Vol. 9, No.1 (Supplement), No. 745.
45. Al-Hendy A , Thomas J, Eyzaguirre B. Towards gene therapy in reproduction: In vitro and in vivo gene transfer to human and murine endometrium using adenoviral vectors. Eighth Annual Meeting, Texas Forum on Female Reproduction, Houston, Texas, May 2-3, 2002.
46. Al-Hendy A , Lee E, Eyzaguirre E, Copland J. Towards gene therapy of uterine fibroids: Adenovirus-mediated expression of dominant negative estrogen receptor induces apoptosis in human leiomyoma cells and inhibits tumor growth in nude mice. Eighth Annual Meeting, Texas Forum on Female Reproduction, Houston, Texas, May 2-3, 2002.
47. Al-Hendy A , Thomas J 1*, Eyzaguirre E 2*. Towards gene therapy in reproduction: in vitro and in vivo gene transfer to human and murine endometrium using adenoviral vectors. Fifth Annual Meeting of the American Society of Gene Therapy, Boston, Massachusetts, June 5-9, 2002.
48. Al-Hendy A , Lee E, Eyzaguirre E, Copland J. Towards gene therapy of uterine fibroids: Adenovirus-mediated expression of dominant negative estrogen receptor induces apoptosis in human leiomyoma cells and inhibits tumor growth in nude mice. Fifth Annual Meeting of the American Society of Gene Therapy, Boston, Massachusetts, June 5-9, 2002 (Podium Presentation).
49. Al-Hendy A , Wang H, Copland J. ER/PR receptors in the endocervix. Important implications for hormone replacement therapy after supracervical hysterectomy. 50th Annual Scientific Meeting, Society of Gynecologic Investigation, Washington, DC, March 27-30, 2003.
50. Al-Hendy A , Salama S. Association of polymorphism in estrogen receptor α gene with susceptibility to uterine leiomyomas. 50th Annual Scientific Meeting, Society of Gynecologic Investigation, Washington, DC, March 27-30, 2003 (Podium
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presentation).
51. Al-Hendy A , Lee E, Wang H, Copland J. Gene therapy for uterine fibroids II: Adenovirus-mediated expression of dominant negative estrogen receptor ablates pre-existing leiomyomas in nude mice. 50th Annual Scientific Meeting, Society of Gynecologic Investigation, Washington, DC, March 27-30, 2003.
52. Al-Hendy A , Lee E, Wang H, Copland J. Gene Therapy for uterine fibroids II: Adenovirus-mediated expression of dominant negative estrogen receptor ablates pre-existing leiomyomas in nude mice. Ninth Annual Meeting, Texas Forum on Female Reproduction, Houston, Texas, April 24-25, 2003.
53. Al-Hendy A , Lee E, Wang H, Copland J. Gene therapy for uterine fibroids II: Adenovirus-mediated expression of dominant negative estrogen receptor ablates pre-existing leiomyomas in nude mice. 6th Annual Meeting of the American Society of Gene Therapy, Washington DC, June 4-8, 2003.
54. Al-Hendy A , Wang H, Copland J. ER/PR receptors in the endocervix. Important implications for hormone replacement therapy after supracervical hysterectomy. Tenth Annual Meeting, Texas Forum on Female Reproduction, Houston, Texas, April 22-23, 2004.
55. Al-Hendy A , Wang H, Copland J. ER/PR receptors in the endocervix. Important implications for hormone replacement therapy after supracervical hysterectomy. National Women health week, Galveston, Texas, May 12, 2004
56. Al-Hendy A, Sonia Robazetti, Mohammed Zaidan, Jukka Tenhunen, Hui-Qun Wang and Salama A. Salama. Novel Model of Parturition Explains the Higher Prevalence of Preterm Labor in African Americans. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
57. Al-Hendy A, Mohammed Zaidan, Mahmoud Eltorky, Salama A. Salama, Hui-Qun Wang, and Manubai Nagamani. Inhibitors of Catechol-O-Methyl Transferase Enzyme Exhibit Estrogen Antagonist Effects on Female Reproductive Tract. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
58. Al-Hendy A & Salama A. Salama. A Functional Polymorphism in Catechol-O-Methyl Transferase Gene Explains Increased Risk of Uterine Leiomyomas in Black Americans. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005. (Podium presentation)
59. Salama A. Salama* & Al-Hendy A. Catechol-O-Methyl Transferase Inhibitors and 2-Methoxyestradiol Suppress Leiomyoma Cell Proliferation: Potential Medical Therapy for Uterine Fibroids. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
60. Salama A. Salama*, Ho SL, Hui Q. Wang, Jukka Tenhunen, and
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Al-Hendy A. Hormonal Regulation of Catechol-O-Methyl Transferase Activity in Uterine Leiomyoma. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
61. Salama A. Salama*, PhD and Al-Hendy A, MD PhD. Retinoic Acid Up-Regulates Catechol-O-Methyl Transferase Promoters: Potential Mechanism for the Mitogenic Effect of Retinoic Acid on Leiomyomas Cells. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
62. Al-Hendy A, Manubai Nagamani, Randall J. Urban, Salama A. Salama, Jorge Chedrese, Hui-Qun Wang, and Mohammad Jamaluddin. Regulation of Catechol-O-Methyl Transferase (COMT) Expression in Granulosa Cells: A Novel Model for Follicular Atresia in Polycystic Ovary Syndrome; Potential Treatment with COMT Inhibitors. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005. (J Soc Gynecol Investig Vol. 12, No. 2 (Supplement), February 2005, PP 295A) (podium presentation)
63. Ghassan M.Saed, Al-Hendy A, Salama A. Salama and Michael P. Diamond. Transfection with adenovirus expressing cyclo-oxygenase-2 antisense reverses adhesion phenotype in human adhesion fibroblasts. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005. (podium presentation)
64. Marwa Kamel*, Salama A. Salama, Gregory Christman and Al-Hendy A. Uterine Fibroids Gene Therapy: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005, J Soc Gynecol Investig Vol 12, No. 2 (suppl) pp.94A.
65. Al-Hendy A., Hui Q. Wang, and Salama A. Salama. Cell Therapy of Ovarian Failure: Intraovarian transplanted Granulosa Cells Successfully Engraft and Repopulate Growing Follicles. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005. (Plenary session presentation)
66. Al-Hendy A . Gene Therapy of Uterine Fibroids: Adenovirus-Mediated Expression of Dominant Negative Estrogen Receptor Inhibits ERE-Reporter Transactivation in Rat and Human Leiomyoma Cells. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
67. Al-Hendy A, Hui Q. Wang, and Salama A. Towards Gene Therapy of Ovarian Failure: Intraovarian Injected Adenovirus Successfully Transduce Granulosa and Stromal but not Germ cells. Salama. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005. (podium presentation)
68. Al-Hendy A , John Chiorini, and Giovanni Di Pasquale. Towards Gene Therapy for Uterine Fibroids: Adeno-Associated Virus can Infect Human and Rat Leiomyoma cells. 52nd Annual Scientific Meeting, Society of Gynecologic Investigation, Los Angeles, March 23-26, 2005.
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69. Al-Hendy A, Marwa Kamel*, Gregory Christman and Salama A. Salama. Uterine Fibroids Gene Therapy: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells. 8th Annual scientific meeting, American Society of Gene Therapy, St. Louis, June 1-5, 2005.
70. Al-Hendy A., Hui Q. Wang, and Salama A. Salama. Cell Therapy of Ovarian Failure: Intraovarian transplanted Granulosa Cells Successfully Engraft and Repopulate Growing Follicles. 8th Annual scientific meeting, American Society of Gene Therapy, St. Louis, June 1-5, 2005.
71. Al-Hendy A . Gene Therapy of Uterine Fibroids: Adenovirus-Mediated Expression of Dominant Negative Estrogen Receptor Inhibits ERE-Reporter Transactivation in Rat and Human Leiomyoma Cells. 8th Annual scientific meeting, American Society of Gene Therapy, St. Louis, June 1-5, 2005.
72. Al-Hendy A and Salama A. Salama. A Functional Polymorphism in Catechol-O-Methyl Transferase Gene Explains Increased Risk of Uterine Leiomyomas in Black Americans. 11th annual meeting of Texas Forum on Female Reproduction April 14-15, 2005. (Podium presentation)
73. William W. Au, Salama A. Salama, Hernan Sierra-Torres, Al-Hendy A.Susceptibility to and Molecular Intervention of Cervical Cancer. The International Conference on Environmental Mutagens, San Francisco, September 2 - 8, 2005
74. Sana M Salih, MD1*, Salama A Salama, PhD1*, Mohammad Jamaluddin, PhD1*, Manubai Nagamani, MD1* and Ayman Al-Hendy, MD1*.Cyclic variations of Catechol-O-Methyl Transferase (COMT) Expression in Human Endometrium and hormonal regulation of COMT in Human Stromal Endometrial Cell line. 53rd Annual Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
75. Sana M Salih, MD1*, Manubai Nagamani, MD1*, Antonie Duleba, MD1* and Ayman Al-Hendy, MD 1*. Reduced Levels of Urinary 2 Hydroxy Estrogens in Polycystic Ovary Syndrome, An Insight into Pathogenesis of follicular atresia.. 53rd Annual Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
76. Salama A. Salama, Abdelhakim Ben Nasr, Raghvendra. K Dubey, and Ayman-Al-Hendy.2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in human leiomyomas cells: A potential treatment for Uterine fibroids 53rd Annual Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
77. Marwa W. Kamel, Salama A. Salama, and Ayman Al-Hendy. Adenovirus expressing Cyclooxgenase-2 antisense down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. 53rd Annual
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Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
78. Melissa J. Wentz and Ayman Al-Hendy. Hormonal Regulation of Catechol-O-Methyltransferase Expression in Human Myometrial Cells 53rd Annual Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
79. Essam R. Othman & Ayman Al-Hendy.Gene Therapy of Endometriosis: Adenovirus mediated Expression of Dominant Negative Estrogen Receptor induces Apoptosis in Human Endometriotic Cells. 53rd Annual Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
80. Melissa J. Wentz, Leili Shi, Shao-Qing Shi, Salama A. Salama, Robert E Garfield and Ayman Al-Hendy. Potential Uses for COMT Inhibitors during Pregnancy.
53rd Annual Scientific Meeting, Society of Gynecologic Investigation, Toronto, March 22-25, 2006.
81. Kamel M, Salama S, Christman G, Wang H and Al-Hendy A. Gene Therapy of Uterine Fibroids: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells. Ninth Annual Meeting of the American Society of Gene Therapy, Baltimore, Massachusetts, June 2-7, 2006.
82. Azab Samar, Salama Salama, and Ayman Al-Hendy. Can 2-methoxyestradiol modulate Cancer Multidrug resistance?A novel approach for chemosensitizing breast cancer cells to doxorubicin. Twelfth Annual Meeting, Texas Forum on Female Reproduction, Houston, Texas, April 21-22, 2006.
83. Dong Zhang, Willie Zoma, Hala Fouad, Allison Loveland, and Ayman Al-Hendy. Expression of Oct4 and SCF-R in Adult Human Ovary. Twelfth Annual Meeting, Texas Forum on Female Reproduction, Houston, Texas, April 21-22, 2006.
84. Mohsen Ghadami, Rebecca Chilvers, and Ayman Al-Hendy. Toward gene therapy of premature ovarian failure: Adenovirus expressing human FSH receptor corrects the inactivating Finnish C566T mutation. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007. (Podium presentation)
85. Samar Azab, Salama Salama, Ashraf Abdel-Naim, Amani Khalifa, Ebtehal El-Demerdash, Ayman Al-Hendy. Can 2-methoxyestradiol modulate Multidrug resistance?A new role for 2-methoxyestradiol in chemosensitizing resistant breast cancer cells. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007. (Podium presentation).
86. Memy H Hassan, Salama A. Salama and Ayman Al-Hendy. Memy I: A novel animal model for uterine leiomyoma using adenovirus-enhanced human fibroid explants in SCID mice. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
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87. Dong Zhang, Hala Fouad, Willie Zoma, Abdou Mohamed Salama, Salama, Wentz, Melissa J., and Ayman Al-Hendy. Expression of germline specific markers in adult murine ovarian cell aggregates. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
88. Melissa Wentz, Hassan Harirah, and Ayman Al-Hendy. Catechol-O-Methyltransferase is differentially expressed in fetal membrane tissue obtained from non-laboring versus laboring pregnant women. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
89. Sana Salih, Manubai Nagamani, Ayman Al-Hendy, and Salama Salama. Estrogen and Tamoxifen modulate the expression of key estrogen metabolizing enzymes in endometrial cancer cells. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
90. Salama salama, sana salih, ayman Al-Hendy. Progesterone alter the expression of estrogen-metabolizing genes in endometrial cancer cells: potential mechanism for the protective effect of progesterone against endometrial cancer. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
91. Memy Hassan, Salama Salama, Dong Zhang, and Ayman Al-Hendy. Towards fibroid gene therapy: Adenovirus mediated delivery of dominant negative estrogen receptor shrinks uterine leiomyoma tumors in Eker rats. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
92. Memy Hassan, Salama Salama, David Curiel, and Ayman Al-Hendy. Towards gene therapy of uterine fibroids: Fiber modified adenovirus show higher expression in human leiomyoma cells compared to matched normal myometrial cells. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
93. Essameldine Othman, Daniela Hornung, Hosam Salem, Essam Khalifa, Tarek Elmetwally, and Ayman Al-Hendy. Serum cytokines as a potential biomarkers for non-surgical prediction of endometriosis. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
94. Essameldine Othman, David Curiel, Ayman Al-Hendy. Towards gene therapy of endometriosis: Targeting adenovirus to human endometriotic cells using tissue specific promoters and fiber modified viruses. 54th Annual Scientific Meeting, Society of Gynecologic Investigation, Reno, March 13-16, 2007.
95. Dong Zhang , Mohamed Al-Hendy and Ayman Al-Hendy. Green Tea Extract (EGCG) Inhibits Proliferation of Human Leiomyoma Cells. 55th Annual Scientific Meeting, Society of Gynecologic Investigation, San Diego, CA March 26-29, 2008.
96. Ghadami Mohsen, Ayman Al-Hendy. Intravenously Injected Bone Marrow Cells Restore Ovarian Folliculogenesis and Steroid Hormones Production in Female
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FSHR (-/-) FORKO Mice. 55th Annual Scientific Meeting, Society of Gynecologic Investigation, San Diego, CA March 26-29, 2008.
97. Ghadami Mohsen, Ebtehal Eldemerdash, Manubai Nagamani, Jorge Chedress, Ram Sairam, Ayman Al-Hendy Toward Gene Therapy of Premature Ovarian Failure: Intraovarian Injection of Adenovirus Expressing Human FSH receptor Restores Folliculogenesis in FSHR (-/-) FORKO Mice. 55th Annual Scientific Meeting, Society of Gynecologic Investigation, San Diego, CA March 26-29, 2008.
98. Memy H Hassan, Dong Zhang, Salama A. Salama,Farid M.A. Hamada, Hossam M.M. Arafa, Hala Fouad, Cheryl C. Walker and Ayman Al-Hendy. Towards Fibroids Gene Therapy: Adenovirus Mediated Delivery of Herpes Simplex Virus 1 Thymidine Kinase Gene /Ganciclovir Shrinks Uterine Leiomyoma in The Eker Rat Model. 55th Annual Scientific Meeting, Society of Gynecologic Investigation, San Diego, CA March 26-29, 2008.
99. Memy H Hassan, Dong Zhang, Hala Fouad, Cheryl C. Walker and Ayman Al-Hendy. Inhibitors of Catechol O-Methyl Transferase Shrinks Uterine Fibroids in the Eker Rat Model. 55th Annual Scientific Meeting, Society of Gynecologic Investigation, San Diego, CA March 26-29, 2008.
100. Melissa J. Wentz. Hassan Harirah and Ayman Al-Hendy. Inhibition of Catechol-O-Methyl Transferase Activity Dramatically Reduces PGE2 Production by Human Amniotic Explants. 55th Annual Scientific Meeting, Society of Gynecologic Investigation, San Diego, CA March 26-29, 2008.
101. Dong Zhang , Mohamed Al-Hendy and Ayman Al-Hendy. Green Tea Extract (EGCG) Inhibits Proliferation of Human Leiomyoma Cells. 41st SSR Annual Meeting, in Kailua-Kona, Hawaii.May 27-30, 2008.
102. Ghadami Mohsen, Ebtehal Eldemerdash, Manubai Nagamani, Jorge Chedress, Ram Sairam, Ayman Al-Hendy Bone Marrow Transplantation Restores Folliculogenesis in FSHR (-/-) FORKO Mice. American society of Reproductive Medicine Annual Scientific Meeting, San Francisco, CA Nov 14-17, 2008. (podium presentation)
103. Chakradhari Sharan, Tarannum Jaleel and Ayman Al-Hendy. Vitamin D inhibition of human leiomyoma cells proliferation could partially explains high incidence in African American women.11th RCMI international symposium on health disparity. Dec 1-4, 2008, Honolulu, Hawaii. (Podium presentation)
104. Chandrasekhar Thota, Ram Menon, and Ayman Al-Hendy. Single nucleotide polymorphism in COMT gene and preterm labor in African Americans. 11th RCMI international symposium on health disparity. Dec 1-4, 2008, Honolulu, Hawaii. (Podium presentation)
105. Chandrasekhar Thota, Ramkumar Menon, Stephen Fortunato and Ayman Al-Hendy. A single nucleotide polymorphism in fetal COMT gene is associated with
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preterm birth in African Americans. 56th Annual Scientific Meeting, Society of Gynecologic Investigation, Glasgow, Scotland, March 18-21, 2009.
106. Vargis E, Robertson K, Resse J, Al-Hendy A, Mahadevan-Jansen A. Detection of Preterm Labor with Raman Spectroscopy. Advances in Optics for Biotechnology, Medicine and Surgery XI: Clinical Challenges and Research Solutions. Burlington, VT, June 2009.
107. Sunil K. Halder and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Reduces Profibrotic Gene Expressions in Human Uterine Leiomyoma Cells. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, Florida, March 24-27, 2010.
108. Sunil K. Halder and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Reduces Transforming Growth Factor (TGF) β3-Induced Profibrotic Gene Expressions in Human Uterine Leiomyoma Cells. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, Florida, March 24-27, 2010.
109. Sunil K. Halder, Chakradhari Sharan, Hassan Harirah and Ayman Al-Hendy. Lower Serum Levels of Vitamin D3 is a Risk Factor for Uterine Fibroids in African Americans. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, Florida, March 24-27, 2010.
110. Sunil K. Halder, Chakradhari Sharan and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Reduces Growth of Uterine Leiomyomas in Eker Rats. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, Florida, March 24-27, 2010.
111. Sunil K. Halder, J. Shawn Goodwin, and Ayman Al-Hendy. 1, 25-dihydroxyvitamin D3 Downregulates Estrogen Receptor alpha (ER-α) in Uterine Leiomyoma Cells. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, Florida, March 24-27, 2010.
112. Sangeeta Nair and Ayman Al-Hendy. Human Adipocytes-Conditioned Media Enhance Proliferation of Human Leiomyoma Cells Via Proinflammatory Cytokine-Dependent Pathway.57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, USA, March 24-27, 2009.
113. Sangeeta Nair and Ayman Al-Hendy. Human Endometrial Glandular Epithelial Cells (EGEC) Are Regulated by TNF[alpha] Secreted in Adipocytes-Conditioned Media. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, USA, March 24-27, 2009.
114. Sangeeta Nair and Ayman Al-Hendy. Human Adipocytes-Conditioned Media Modulates the Expression of Angiogenic Factors in Human Endometrial Glandular Epithelial Cells. An In Vitro Model for Obesity-Induced Implantation Dysfunction. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, USA, March 24-27, 2009.
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115. Sangeeta Nair, Robyn Tamboli, Pamela Marks, Naji Abumrad and Ayman Al-Hendy. Roux-en-Y Gastric Bypass Induced Weight Loss Improves Reproductive Hormone Profile in Women. 57th Annual Scientific Meeting, Society of Gynecologic Investigation, Orlando, USA, March 24-27, 2009.
116. Chandrasekhar Thota, Ramkumar Menon, Stephen J Fortunato, and Ayman Al-Hendy. Vitamin D3 Deficiency Is A Novel and Important Risk Factor for Preterm Labor In African American and Caucasian Women. Society of Gynecologic Investigation, Orlando, FL, March 24 − 27, 2010
117. Chandrasekhar Thota, Bobb Lesley, Monique McAllister, Darryl Hood, and Ayman Al-Hendy. Developmental reprogramming in uterus of rats exposed in utero to Benzo (a) Pyrene: Increased incidence of preterm birth in the dams. Society of Gynecologic Investigation, Orlando, FL, March 24 − 27, 2010
118. Chandrasekhar Thota, and Ayman Al-Hendy. Effect of Vitamin D on Inflammatory Proteins Expression in Immortalized Term Human Myometrial Cells. Society of Gynecologic Investigation, Orlando, FL, March 24 − 27, 2010
119. Chandrasekhar Thota, and Ayman Al-Hendy. Longitudinal Gestational Changes In Catechol-O-Methyltransferase Activity in Myometrium of Sprague Dawley Rats. Society of Gynecologic Investigation, Orlando, FL, March 24 − 27, 2010.
120. Vargis E, Robertson K, Al-Hendy A, Reese J, A Mahadevan-Jansen. Detecting changes during pregnancy with Raman spectroscopy. SPIE: Photonics West 2010. San Francisco, CA, January 2010.
121. Vargis E, Robertson K, Al-Hendy A, Reese J, A Mahadevan-Jansen. Detecting changes during pregnancy with Raman spectroscopy. Advanced Biomedical and Clinical Diagnostic Systems VIII - SPIE Proceedings 7555-3, 2010.
122. Sangeeta Nair and Ayman Al-Hendy. Adipocytes- conditioned media modulates the cellular and molecular responses in human endometrial glandular epithelial cells. American Society of Reproductive Medicine, Denver, CO, Oct 23-27 2010 (Podium presentation)
123. Mohamed Abdelraheem and Ayman Al-Hendy. Serum Vitamin D3 Level Inversely Correlates with Total Fibroid Tumor Burden in Women with Symptomatic Uterine Fibroid, American Society of Reproductive Medicine, Denver, Colorado. October 23-27, 2010 (Podium presentation)
124. Halder SK, Sharan C and Al-Hendy A. Vitamin D Treatment Induces Dramatic Shrinkage of Uterine Leiomyomas Growth in the Eker Rat Model. 66th Annual Meeting for American Society for Reproductive Medicine (ASRM), Denver, CO, October, 23-27, 2010. (Podium presentation)
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125. Chandrasekhar Thota, and Ayman Al-Hendy . Infection of contractile associated factors by IL-1β in uterine myometrial smooth muscles is regulated by vitamin D. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
126. Chandrasekhar Thota, and Ayman Al-Hendy . Vitamin D reverses Lipopolysaccharide-mediated cytokine induction and increases progesterone receptor A expression in immortalized myometrial smooth muscle cells. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011. (Podium presentation)
127. Chandrasekhar Thota, Prashant Mishra and Ayman Al-Hendy . Vitamin D exerts robust anti-inflammatory effect on human myometrium: a possible role of hypovitaminosis D in preterm labor. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
128. Anthony E Archibong, Chakradhari Sharan, Ayman Al-Hendy. Cancer chemotherapy alters folliculogenesis and estrous cycle length in treated mice. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
129. Anthony E Archibong, Chakradhari Sharan, Ayman Al-Hendy. Restoration of fertility to chemotherapy- treated mice with nucleated peripheral blood cells. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
130. Eman R Mahmoud, Ahmed F Ahmed, Nagah M AboElfotoh, Eman A Mohamed, Ayman Al-Hendy. Maternal Vitamin D supplementation decreases risk of rickets in children but effect is modified by parity , a case control study in southern Egypt. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
131. Mohammed S Abdelraheem , Ibrahim M Hassanin, Abdou S Ait-Allah, Sabri M Mohammed, Ayman Al-Hendy. Proteomic pattern of follicular fluid accurately predicts IVF outcome in women over 35 years of age. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
132. Sangeeta Nair and Ayman Al-Hendy. Proinflammatory Cytokine TNFα Regulates Sex steroid synthesizing enzymes in uterine leiomyoma cells. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
133. Sangeeta and Ayman Al-Hendy. Towards Uterine Fibroids Gene Therapy: Targeted Adenovirus Vector (Ad-SSTR-RGD-TK/GCV) Provides Superior killing of Human Leiomyoma cells compared to Unmodified First Generation Adenoviral Vectors. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
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134. Sunil K. Halder, PhD and Ayman Al-Hendy, MD, PhD.Vitamin D3 Inhibits Progesterone Receptors (PR-A/PR-B) Expression in Human Leiomyoma Cells. 58th meeting of the Society of Gynecologic Investigations, Miami Beach, FL, March 16-19, 2011.
135. Sangeeta Nair, David T Curiel and Ayman Al-Hendy. Uterine Fibroids Gene Therapy: Targeted Adenovirus Vector (Ad-SSTR-RGD-TK/GCV) Provides Superior inhibition of Human Leiomyoma cells than human uterine smooth muscle cells. 14th Annual Meeting of American Society of Gene & Cell Therapy, Seattle, WA, May 18-21, 2011
136. Halder SK, C. Sharan, K. G. Osteen, A. Al-Hendy. 1, 25 dihydroxy vitamin d3 is a potent anti-tumor agent for non-surgical treatment of uterine leiomyoma in eker rats. 67th Annual Meeting for American Society for Reproductive Medicine (ASRM), Orlando, FL, October, 15-19, 2011. (Podium presentation)
137. S. Nair, G. Saed, N. Nwaobasi, H. Atta, A. Al-Hendy. Towards gene therapy of pelvic post-operative adhesions: targeting adenovirus towards human adhesion cells. 67th Annual Meeting for American Society for Reproductive Medicine (ASRM), Orlando, FL, October, 15-19, 2011.
138. S.K. Halder, K.G. Osteen, A. Al-Hendy. 1, 25-Dihydroxy Vitamin D3 regulates Steroid Hormone Functions in Human Uterine Leiomyoma Cells. 67th Annual Meeting for American Society for Reproductive Medicine (ASRM), Orlando, FL, October, 15-19, 2011.
139. C. Sharan, S. Nair, S. Halder, A. Al-Hendy. UTERINE FIBROID-SPECIFIC STEM CELLS ENHANCE SUBCUTANEOUS TUMOR FORMATION IN A NOVEL MOUSE MODEL (SHARAN-2). 68th annual meeting, American Society of Reproductive Medicine (ASRM), San Diego, California Oct 20-24th, 2012 (Podium Presentation).
140. Sharan, S. Nair, S. Halder, S. Maitra, A. Al- Hendy . DIFFERENTIAL EXPRESSION OF CHROMATIN MODIFYING PROTEINS BETWEEN NORMAL MYOMETRIUM VERSUS MYOMETRIUM FROM FIBROID UTERI SUGGESTS INVOLVEMENT OF THE EPIGENOME IN FIBROID BIOLOGY. 68th annual meeting, American Society of Reproductive Medicine (ASRM), San Diego, California Oct 20-24th, 2012 (Podium Presentation).
141. C. Sharan, S. Nair, S. Halder, S. Maitra, A. Al- Hendy . DIFFERENTIAL EXPRESSION OF CHROMATIN MODIFYING PROTEINS BETWEEN FIBROID TUMOR LESIONS VERSUS ADJACENT MYOMETRIUM SUGGESTS INVOLVEMENT OF THE EPIGENOME IN FIBROID BIOLOGY. 68th annual meeting, American Society of Reproductive Medicine (ASRM), San Diego, California Oct 20-24th, 2012
142. N. M. Fletcher, A. Al-Hendy, M. Diamond, G. M. Saed UTERINE FIBROIDS ARE CHARACTERIZED BY AN IMPAIRED ANTIOXIDANT CELLULAR
SYSTEM: POTENTIAL ROLE OF HYPOXIA IN THE PATHOPHYSIOLOGY OF FIBROIDS.. 68th annual meeting, American Society of Reproductive Medicine (ASRM), San Diego, California Oct 20-24th, 2012
143. S. K. Halder, K. G. Osteen, W. Khoder, A. Chaudhry, A. Al-Hendy. VITAMIN D3 REGULATES BETA-CATENIN PROTEIN EXPRESSION IN HUMAN FIBROID CELLS: IMPLICATIONS FOR Med12 ROLE IN FIBROID PATHOGENESIS.. 68th annual meeting, American Society of Reproductive Medicine (ASRM), San Diego, California Oct 20-24th, 2012
144. Sunil K Halder, Archana Laknaur, Kevin G Osteen, Ayman Al-Hendy. Vitamin D3 Reduces Tumor-Promoting mTOR Signaling Targets by Inducing DDIT4 in Human Uterine Fibroid Cells. 60th Annual meeting, Society of Gynecologic Investigation (SGI), March 20-23, 2013.
145. Sunil K Halder, Sangeeta Nair, Chakradhari Sharan, Ayman Al-Hendy. Vitamin D3 Reverse Developmental Reprogramming by Modulating EZH2 Histone Methyltransferase Activities in Human Fibroid Stem Cells. 60th Annual meeting, Society of Gynecologic Investigation (SGI), March 20-23, 2013.
146. Sangeeta Nair, Chakradhari Sharan, Waseem Khoder, Sarbani Maitra, Ayman Al-Hendy. Epigenome and Risk of Uterine Fibroids (UF): Altered Phosphorylation of Histone Methyltransferase EZH2 in Stem Cells from UF & Adjacent Myometrium. 60th Annual meeting, Society of Gynecologic Investigation (SGI), March 20-23, 2013.
None-Hypercalcemic Vitamin D Receptor Activator, Inhibits Proliferation of Human Uterine Leiomyoma Cells. 60th Annual meeting, Society of Gynecologic Investigation (SGI), March 20-23, 2013.
Hendy. Epigenetics of Preterm Labor: Distinct Patterns of Chromatin Modifying Enzymes and Altered Expression of Cytokines in Myometrial Tissue of Rats Exposed In Utero to Benzo(a)Pyrene. 60th Annual meeting, Society of Gynecologic Investigation (SGI), March 20-23, 2013.
149. Sangeeta Nair, Chakradhari Sharan, Jyotsna Thota, Ahsen Chaudhury, Sarbani Maitra, Ayman Al-Hendy. Differential Expression of Steroid Receptors (ER, PR, VDR) in Stem Cells from Myometrium in Women with (MyoF) Versus without (MyoN) Uterine Fibroids; MyoF as a Pre-Tumor State. 60th Annual meeting, Society of Gynecologic Investigation (SGI), March 20-23, 2013.
150. C. Sharan, S. Halder, S. Nair, J. Segars, A. Al-Hendy. PARICALCITOL, VITAMIN D3 RECEPTOR AGONIST IS SUPERIOR TO VITAMIN D3 IN REDUCING
PROLIFERATION OF HUMAN UTERINE LEIOMYOMA CELLS. 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
E.-E. R. Othman, D. Hornung, A. Al-Hendy. CYTOKINES AND THEIR SOLUBLE RECEPTORS IN THE SERUM OF ENDOMETRIOSIS PATIENTS, POTENTIAL BIOMARKERS?. 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12- 17, 2013
151. S. Nair, D. Curiel, C. Sharan, A. Al-Hendy. TOWARDS UTERINE FIBROIDS GENE THERAPY: FIBROID-TARGETED ADENOVIRUS (AD-SSTR-RGD-TK/GCV) DEMONSTRATES ENHANCED INHIBITION OF TUMOR GROWTH IN NUDE MICE. 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
152. N. M. Fletcher, M. G. Saed, H. M. Abu-Soud, A. Al-Hendy, M. P. Diamond, G. M. Saed. DISTINCT OXIDATIVE STRESS PROFILE IN UTERINE FIBROIDS VERSUS ADJACENT MYOMETRIUM. 69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
153. S. K. Halder, A. Laknaur, K. G. Osteen, A. Al-Hendy. VITAMIN D3 REGULATES WNT-SIGNALING PATHWAY ASSOCIATED GENE EXPRESSIONS IN HUMAN UTERINE FIBROID CELLS.
69th American society of reproductive medicine annual meeting conjoint with the International Federation of fertility societies, Boston Convention & Exhibition Center, Boston, Massachusetts, USA, Oct 12-17, 2013
154. Foster Teri-Lee, Thota C and Al-Hendy A. Effects of Benzo(a)pyrene During Pregnancy. 2014 Annual Clinical Meeting of the American College of Obstetricians and Gynecologists. Chicago, IL, USA, April 26-30, 2014.
155. Archana Laknaur, Teri-Lee Foster, Daryl B Hood, Ayman Al-Hendy, Chandrasekhar Thota. Effects of Benzo(a)pyrene, an Environmental Toxin in Rat Pregnancy: Changes in Histone Deacetylases, Inflammatory Pathway Markers and Contractile Proteins in Myometrium. 61st Annual meeting, Society of Gynecologic Investigation (SGI), March 26-29, 2014, Florence, Italy.
156. Archana Laknaur, Pandu RR Gangula, Kalpana Ravella, Ayman Al-Hendy, Chandrasekhar Thota. Effect of Vitamin D on Myometrial Contractility and Gestation Length in Normal and Vitamin D Deficient Mice Stimulated with Lipopolysaccharides. 61st Annual meeting, Society of Gynecologic Investigation (SGI), March 26-29, 2014, Florence, Italy.
157. Julie AW Stilley, Debora E Christensen, Kristin B Dahlem, Ayman Al-Hendy, Patricia A Kirby, Deborah L Segaloff. FSH Receptor in Extra-Gonadal Reproductive Tissues and Placentae. 61st Annual meeting, Society of Gynecologic Investigation (SGI), March 26-29, 2014, Florence, Italy.
158. Chakradhari Sharan, Sunil K Halder, Ayman Al-Hendy, Sangeeta Nair. Paricalcitol, an Analogue of Vitamin D3 Potentially Inhibits Fibroid Growth in In Vivo Nude Mice. 61st Annual meeting, Society of Gynecologic Investigation (SGI), March 26-29, 2014, Florence, Italy.
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159. Sangeeta Nair, Archana Laknaur, Chakradhari Sharan, Ayman Al-Hendy Altered Estrogen Signaling in Stem Cells from Uterine Fibroid and Adjacent Myometrium. 61st Annual meeting, Society of Gynecologic Investigation (SGI), March 26-29, 2014, Florence, Italy.
160. Sunil K Halder, Chakradhari Sharan, Kevin G Osteen, Ayman Al-Hendy. The Med12 Gene Is Functionally Associated with Growth of Human Uterine Fibroid Cells. 61st Annual meeting, Society of Gynecologic Investigation (SGI), March 26-29, 2014, Florence, Italy.
161. S. K. Halder, M. P. Diamond, A. Al-Hendy. The Mediator Complex subunit 12 (Med12) modulates the expression of extracellular matrix genes in human uterine fibroid cells. American society of reproductive medicine annual meeting, , Honolulu, Hawaii, USA, Oct 18-22, 2014
162. S. A. Mohamed, S. Shalaby, A. Laknaur, S. Nair, A. Al-Hendy. Tumor-targeted adenoviral vectors show enhanced efficacy against uterine fibroids in a murine model. American society of reproductive medicine annual meeting, Honolulu, Hawaii, USA, Oct 18-22, 2014
163. Sara Mohamed, Ayman Al-Hendy, Michael Diamond, Paul Brown. Atypical Presentations of Molar Pregnancy. Paired Diagnostic Role of Imaging and β-HCG Measurement. 2015 AIUM Annual Convention hosting the World Federation of Ultrasound in Medicine and Biology (WFUMB) , March 21-25, 2015, at the Walt Disney World Swan and Dolphin Hotel, Lake Buena Vista, Florida.
164. Qiwei Yang, Aymara Mas Perucho, Archana Laknaur, Michael Diamond, Ayman Al-Hendy. Epigenetic Regulation of DNA Damage repair Signaling pathway in human Uterine fibroids. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
165. Mohamed Abdelaziz, Shahinaz Shalaby, Sangeeta Nair, Sara Mohamed, Noura Eziba, David Curiel, Michael Diamond, Ayman Al-Hendy Targeted Adenoviral Vector Demonstrates Enhanced Efficacy and Safety for In Vivo Gene Therapy of Uterine Leiomyoma. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
166. Sunil K Halder, W Hayes McDonald, Archana Laknaur, Michael P Diamond, Ayman Al-Hendy Vitamin D3 Modulates Protein Expression in Uterine Smooth Muscle Cells as Determined By Shotgun Proteomics. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
167. Aymara Mas, Archana Laknaur, Paul M O'Connor, Cheryl L Walker, Michael P Diamond, Carlos Simon, Ayman Al-Hendy Myometrial Tumor-Forming Stem Cells in a Murine Model of Uterine Fibroids Reside in Hypoxic Niches. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
168. Aymara Mas, Sangeeta Nair, Archana Laknaur, Ali Eroglu, Michael P Diamond, Carlos Simon, Ayman Al-Hendy. Establishment of Stro1/CD44 as New Markers for Human Myometrial/Fibroid Stem Cells. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
169. Shahinaz M Shalaby, Sara A Mohamed, Soumia Brakta, Archana Laknaur, David Curiel, Micheal Diamond, Ayman A Al-Hendy Magnetic Nanoparticles Conjugation To Adenovirus Enhances Its Transfection Efficacy Towards Human Uterine Fibroid Tumor Cells.
Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
170. Shahinaz M Shalaby, Aymara Mas Perucho, Sara A Mohamed, Soumia Brakta, Archana Lacnaur, Micheal Diamond, David Curiel, Ayman A Al-Hendy An In Vitro Approach To Transduction of Human Uterine Fibroid Stem Cells By Replication Incompetent Adenovirus Serotype5. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
171. Mohamed Abdelaziz, Noura Eziba, Muhammad Ansar, Nahed Ismail, Michael Diamond, John Lue, Barbara Robinson, Ayman Al-Hendy Vitamin D Elicits Anti-Inflammatory Response in Human Female Detrusor Muscle Cells: Implication for Overactive Bladder Syndrome.
Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
172. Archana Laknaur, Ahsen R Chaudhry, Ayman Al-Hendy, Chandrasekhar Thota. Vitamin D Inhibits Interleukin-1 Induced Increase in Contractile Proteins in Primary Detrussor Smooth Muscle Cells of Urinary Bladder. Society of Reproductive Investigations (SRI) 62nd annual meeting. March 25-28, 2015. San Francisco, CA, USA
173. Oct. 19, 2015, 11:15 - 11:30 AM O-73 - EARLY LIFE EXPOSURE TO ESTROGEN-MIMICS INCREASE THE OCCURRENCE OF UTERINE FIBROIDS VIA EXPANSION OF MYOMETRIAL STEM CELL POPULATION A. Mas,1 L. Elam,1 C. Walker,2 C. Simon,3 M. P. Diamond,1 W. Thompson,4 A. Al-Hendy1; 1Department of Obstetrics and Gynecology, Georgia Regents University, Augusta, GA, 2Department of Obstetrics and Gynecology, Georgia Regents University, Augusta, TX, 3Fundacion Instituto Valenciano de Infertilidad IVI-Universidad de Valencia-INCLIVA, Paterna (Valencia), Spain, 4Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, GA. American Society
of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
174. Oct. 19, 2015, 11:30 - 11:45 AM O-74 - A NOVEL DIAGNOSTIC MOLECULAR BIOIMAGING TOOL TO DISCRIMINATE BETWEEN UTERINE LEIOMYOSARCOMA VERSUS LEIOMYOMA M. K. Khater,1 S. Brakta,2 S. M. Shalaby,2 H. El-Husseini,1 M. Diamond,1 A. Al-Hendy3; 1OB/GYN, GRU, Augusta, GA, 2GRU, Augusta, GA, 3Medical College of Georgia, Georgia Regents Univer, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
175. Oct. 19, 2015, 11:45 - 12:00 PM O-75 - INTRODUCTION OF EXON 2 MUTANT MED12 GENE TRIGGERS ACTIVATION OF WNT/β-CATENIN SIGNALING IN NORMAL HUMAN UTERINE SMOOTH MUSCLE CELLS S. K. Halder, L. A. Elam, A. Laknaur, M. P. Diamond, A. Al-Hendy; Obstetrics and Gynecology, Georgia Regents University, Medical College of Georgia, Augusta, G American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
176. Oct. 19, 2015, 12:00 - 12:15 PM O-76 - EARLY LIFE EXPOSURE TO GENISTEIN PERMANENTLY DECREASES MYOMETRIAL DNA REPAIR CAPACITY, WHICH MAY CONTRIBUTE TO INCREASED RISK OF UTERINE FIBROID DEVELOPMENT Q. Yang,1 A. Mas,1 L. A. Elam,1 L. S. Trevino,2 T. Berry,2 C. L. Walker,2 M. P. Diamond,1 A. Al-Hendy1; 1Georgia Regents University, Augusta, GA, 2Institute of Biosciences and Technology, Houston, TX. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
177. Oct. 19, 2015, 12:30 - 12:45 PM O-6 - HUMAN BONE MARROW MESENCHYMAL STEM CELLS THERAPY RESTORES OVARIAN FUNCTIONS AND REVERSES INFERTILITY IN A PRECLINICAL MODEL OF CHEMOTHERAPY INDUCED PREMATURE OVARIAN FAILURE S. A. Mohamed,1,2 S. M. Shalaby,3,2 S. Brakta,2 M. Abdelaziz,4 W. D. Hill,4 M. Diamond,2 A. Al-Hendy2; 1Obstetric and Gynecology, Mansoura Medical School, Mansoura, Egypt, 2Obstetric and Gynecology, Georgia Medical School, GRU,
Augusta, GA, 3Pharmacology, Tanta Medical School, Gharbeyia, Tanta, Egypt, 4Georgia Medical School, GRU, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
178. Oct. 20, 2015, 7:00 - 8:45 AM P-113 - MYELOPEROXIDASE SERVES AS A REDOX SWITCH THAT REGULATES APOPTOSIS IN HUMAN LEIOMYOMAS M. S. Abusamaan,1 N. M. Fletcher,1 M. G. Saed,1 A. Al-Hendy,2 M. P. Diamond,3 J. M. Berman,1 G. M. Saed1; 1Obstetrics and Gynecology, Wayne State University, Detroit, MI, 2Medical College of Georgia, Georgia Regents Univer, Augusta, GA, 3Georgia Regents University, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
179. Oct. 20, 2015, 7:00 - 8:45 AM P-115 - UTERINE FIBROIDS ARE CHARACTERIZED BY AN ALTERED REDOX BALANCE, FAVORING A PRO-OXIDANT STATE N. M. Fletcher,1 M. G. Saed,1 B. R. Neubauer,1 M. S. Abusamaan,1 A. Al-Hendy,2 M. P. Diamond,3 J. M. Berman,1 G. M. Saed1; 1Obstetrics and Gynecology, Wayne State University, Detroit, MI, 2Medical College of Georgia, Georgia Regents Univer, Augusta, GA, 3Georgia Regents University, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
180. Oct. 20, 2015, 11:30 - 11:45 AM O-182 - EXOSOMES FROM HYPOXIA-DRIVEN HUMAN FIBROID STEM CELLS ACCELERATE TUMOR GROWTH S. Brakta, S. M. Shalaby, M. P. Diamond, A. Zimmerman, I. Helwa, Y. Liu, S. A. Mohamed, L. Gavrilova-Jordan, A. Al-Hendy; GRU, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
181. Oct. 20, 2015, 12:15 - 12:30 PM O-185 - ALTERED DNA REPAIR GENES IN HUMAN UTERINE FIBROIDS ARE EPIGENETICALLY REGULATED VIA EZH2 HISTONE METHYLTRANSFERASE Q. Yang, L. Elam, A. Laknaur, L. Gavrilova-Jordan, J. Lue, M. P. Diamond, A. Al-Hendy; Georgia Regents University, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore,
182. Oct. 20, 2015, 12:30 - 12:45 PM O-186 - SYNERGISTIC EFFECT OF ESTROGEN AND PROGESTERONE ON MYOMETRIAL STEM CELL EXPANSION IN VIVO A. Mas,1 L. Elam,1 M. P. Diamond,1 C. Simon,2 A. Al-Hendy1; 1Department of Obstetrics and Gynecology, Georgia Regents University, Augusta, GA, 2Fundacion Instituto Valenciano de Infertilidad/University of Valencia, INCLIVA, Paterna (Valencia), Spain. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
183. Oct. 21, 2015, 11:15 - 11:30 AM O-211 - THE ONTOGENY OF MYOMETRIAL STEM CELLS IN OCT4-GFP TRANSGENIC MICE S. Brakta, A. Mas, M. P. Diamond, S. M. Shalaby, A. Al-Hendy; GRU, Augusta, GA. American Society of Reproductive Medicine (ASRM) 71st annual meeting. October 17-21, 2015, Baltimore, MD, USA
185- [O-044] Negative Association Between PCOS and Risk of Uterine Leiyomyomas in Caucasian Infertile Women.
Date/Time: Saturday, March 19, 2016 - 8:30 am Session Info: Poster Session: Endometriosis, Fibroids, and
Gynecology (8:30 AM-10:30 AM)
(195) EARLY LIFE DEVELOPMENTAL EXPOSURE TO ENDOCRINE DISRUPTING CHEMICALS INCREASES THE RISK OF ADULT ONSET OF UTERINE FIBROIDS BY PERMANENTLY REPROGRAMING THE EPIGENOME OF MYOMETRIAL STEM CELLS TOWARDS A PRO-FIBROID LANDSCAPE. Q. Yang,1 L. Trevino,2 A. Mas,1 A. Laknaur,1 M. P. Diamond,1 C. L. Walker,2 A. Al-Hendy1; 1OB/GYN, Augusta University, Augusta, GA, 2Texas A&M Health Science Center, Houston, TX. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016 (Prize Paper session).
(196) A KINASE ANCHORING PROTEIN 13 REPRESSES LIGAND-DEPENDENT VITAMIN D RECEPTOR ACTIVITY THROUGH A RHOA SIGNALING PATHWAY IN FIBROID CELLS. C. Washington,1 P. Driggers,1 F. S. Chuong,1 K.C. Cayton Vaught,1 M. Malik,2 A. Al-Hendy,3 J. Segars1; 1Gyn/OB, Johns Hopkins School of Medicine, Baltimore, MD, 2OBG, Uniformed Services University of the Health Sciences,Bethesda, MD, 3Obstetrics & Gynecology,Medical College of Georgia, Georgia Regents University, Augusta, GA. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016 (Prize Paper session).
(197) MYOMETRIAL PROGESTERONE HYPERRESPONSIVNESS IS ASSOCIATED WITH INCREASED RISK FOR THE DEVELOPMENT OF HUMAN UTERINE FIBROIDS. M. K. Omar,1,2 Q. Yang,1 A. Laknaur,1 A. Al-Hendy1;1OB/GYN, Augusta University, Augusta, GA,
2Obstetrics and Gynecology,TantaUniversity, Tanta, Egypt. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016.
(198) FIRST US-BASED PHASE 3 STUDY OF ULIPRISTAL ACETATE (UPA) FOR SYMPTOMATIC UTERINE FIBROIDS (UF): RESULTS OF VENUSI. J. Simon,1 W. H.Catherino,2 J. Segars,3 R. Blakesley,4 A. Chan,4 V. Sniukiene,4 A. Al-Hendy5; 1Women’s Health and Research Consultants, Washington, DC, 2Uniformed Services University of the Health Sciences, Bethesda, MD, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Allergan plc, Jersey City, NJ, 5Augusta University, Augusta, GA. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016.
(199) UMBILICAL CORD BLOOD MESENCHYMAL STEM CELLS AS AN INFERTILITY TREATMENT FOR CHEMOTHERAPY INDUCED PREMATUREOVARIAN FAILURE. S. A. Mohamed,1,2 S. M. Shalaby,3,2 S. Brakta,4 L. Stone,4 M. Ellakany,1 A. Al-Hendy4; 1Obgyn, Mansoura MedicalSchool, Mansoura, Egypt, 2Obgyn, Augusta Medical Center, Augusta, GA, 3Pharma,Tanta Medical School, Tanta, Egypt, 4Obgyn,Augusta Medical School, Augusta, GA. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016.
(200) EARLY-LIFE EXPOSURE TO ENDOCRINEDISRUPTINGCHEMICALS (EDCS) LEADS TO THE DEVELOPMENT OFUTERINE FIBROIDSBY IMPAIRING DNA REPAIR CAPACITY IN MYOMETRIAL STEM CELLS. L. Prusinski,1 Q. Yang,2 A. Mas,3 M. P. Diamond,4 C. Walker,5A. Al-Hendy6; 1Obstetrics and Gynecology, Augusta University, Augusta, GA, 2OB/GYN, Augusta University, Augusta, GA, 3PhD, Paterna (Valencia), Spain, 4Augusta University, Augusta,GA, 5Texas A&M Institute of Biosciences and Technology, Houston, TX, 6Obstetrics & Gynecology, Augusta University, Augusta, GA. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016.
(201) AUTOPHAGY AND FIBROIDS: AUTOPHAGY RELATED PROTEINS ATG4 AND ATG10 ARE DEFECTED IN HUMAN UTERINE FIBROIDS WITH HIGH FREQUENCY. A. El Andaloussi,1 S. Habib,1 G. Soylemez,1 N. Ismail,2 A. Al-Hendy1; 1Dept of Obstetrics & Gynecology,
85
Augusta Univ, Augusta, GA, 2Pathology Clinical Microbiology Division,University of Pittsburgh, Pittsburgh, PA. 72nd American Society of Reproductive Medicine (ASRM), Salt Lake city, UTAH, Oct 15-19, 2016.
(202) Re: 33284 - Hyperandrogenism and Systemic Antioxidant Activity Are Negatively Associated with the Presence of Uterine Leiomyomata in Infertile Women Larisa Suturina1, Lyubov Kolesnikova1, Daria Lizneva2, Zorikto Darzhaev1, Alina Atalyan1, Luidmila Grebenkina1, Leonid Sholohov1, Ludmila Lazareva1, Tatyana Bazarova1, Michael P Diamond, MD2, Ayman Al-Hendy2 and Ricardo Azziz3. ENDO 2017, April 1 – 4, 2017 in Orlando, Florida.
(203) Lauren Prusinski Fernung, Ayman Al-Hendy, Qiwei Yang. Dysregulated DNA double-strand break repair in stem cells from uterine fibroids promotes mutagenesis and propagates uterine tumor development. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA
(204) Mohamed Ali, Qiwei Yang, Lauren Prusinski Fernung, Sara M. Shahin, Nagwa A. Sabri, Ayman Al-Hendy. Vitamin D reverses uterine fibroids associated DNA damage. SRI Annual Meeting. March 6-10, 2018, San Diego, CA, USA
(205) Hoda Elkafas, Osama Badary, Rehab Kamel, Engy M.Elmorsy, Abdeljabar EL Andaloussi, Ayman Al-Hendy. Early Life Exposure to Endocrine Disrupting Chemicals Induces Inflammation-Mediated DNA Damage in Myometrial Stem Cells. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA.
(206) Hoda Elkafas, Ihor Atabiekov, Mohamed Abdelaziz, Nahed Ismail, Abdeljabar El Andaloussi, Ayman Al-Hendy. Diet-Induced Vitamin D Deficiency Promotes Inflammation-mediated DNA Damage in Myometrium. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA.
(207) Hoda Elkafas, Abdeljabar EL Andaloussi, and Ayman Al-Hendy. Emergence of uterine fibroid driver mutations in perturbed myometrial stem cells: the role of Hypovitaminosis D. ASRM Annual Meeting. October 28-1 November, 2017, San Antonio, TX, USA.
(208) Mohamed Ali, Sara M. Shahin, Nagwa A. Sabri, Ayman Al-Hendy. Ulipristal Acetate inhibits Wnt and mTOR signaling pathways in Human Uterine Fibroid Cells. SRI Annual
(209) Mohamed Ali, Archana Laknaur, Sara M. Shahin, Nagwa A. Sabri, Ayman Al-Hendy. Vitamin D synergizes the antiproliferative, apoptotic, antifibrotic and anti-inflammatory effects of ulipristal acetate against human uterine fibroids. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(210) M. Malik, W.H. Catherino, A. Laknaur, M. Ali, A. Al-Hendy, J. Segars, M.A. Borahay. Synergistic effects of simvastatin and ulipristal acetate on uterine leiomyoma. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(211) Mohamed Ali, Qiwei Yang, Sara M. Shahin, Nagwa A. Sabri, Ayman Al-Hendy. Hypovitaminosis D exacerbates DNA damage load and genetic instability in human uterine fibroids which is ameliorated by vitamin D3 treatment. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA.
(212) Lauen Prusinski, A. Mas, Ayman Al-Hendy. Topology of myometrial stem cells inhuman uterus: implications for surgio-pathological distribution of uterine fibroid subtypes. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(213) Lauren Prusinski, A. Mas, Ayman Al-Hendy. Higher abundance of stem cells in human myometrial tissue from African Americans may contribute to the ethnic disparity of uterine fibroids. L. Prusinski, A. Mas, Ayman Al-Hendy. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(214) Lauren Prusinski, A. Mas, Ayman Al-Hendy. The human myometrial stem cell compartment in fibroid-affected uteri is significantly expanded after ovarian steroid hormone exposure. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA
(215) Abdeljabar El Andaloussi. Ayman Al-Hendy . Regulation of PD-1 and leptin receptor expression by estrogen through AKT3 in human uterine fibroids. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(216) Abdeljabar El Andaloussi. P.I. Igboeli. Ayman Al-Hendy . 87
Role of PD-L1 in the immunosurveillance of human uterine fibroids inflammation. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(217) Hoda Elkafas. Abdeljabar El Andaloussi · Ayman Al- Hendy . Emergence of uterine fibroid driver mutations in perturbed myometrial stem cells: the role of hypovitaminosis D. ASRM Annual Meeting. October 28- November 1, 2017 San Antonio, TX, USA
(218) Ihor Atabiekov, Ayman Al-Hendy, Nahed Ismail, Abdeljabar El Andaloussi Ulipristal Acetate Reverses Impaired Autophagy in Human Uterine Fibroids. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA
(219) Abdeljabar El Andaloussi, Prosper Igboeli, Sunil Halder, Ayman Al-Hendy, Nahed Ismail. PD-L1 Expression is Regulated by Med12 and INF-γ in Human Uterine Fibroids. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA
(220) Abdeljabar El Andaloussi, Sunil Halder, Ayman Al-Hendy, Nahed Ismail. Uterine fibroid-specific Med12 mutation disrupts autophagy through β-catenin and GSK-3β. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA
(221) Charles Millard, Ayman Al-Hendy, Shannon D Whirledge. A novel mechanism of action for the uterine fibroid therapy ulipristal acetate. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA
(222) Nicole M Fletcher, Awoniyi O Awonuga, Ira Memaj, Michael P Diamond, Ayman Al-Hendy, Ghassan M Saed. A novel role for the interaction of myeloperoxide and CD11b in leiomyoma cells. SRI Annual Meeting. March 6-10, 2018 San Diego, CA, USA.
