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Curriculum Vitae

Md Khaled Hossain, Ph.D

Professor, Department of Biochemistry and Molecular Biology

University of Rajshahi, Rajshahi-6205, Bangladesh

Tel: +880-1726884046 (cell)

E-mail: khossain@ru.ac.bd

Education

2003 Ph.D. Nagoya University Graduate School of Medicine, Japan

1997 M.Sc (Top class top position) in Biochemistry, University of Rajshahi, Bangladesh

1994 B.Sc (Top class top position) in Biochemistry, University of Rajshahi, Bangladesh

Academic and Professional Appointments

2012-present Professor, Dept. of Biochemistry & Molecular Biology, University of Rajshahi, Bangladesh

2005-2007 Visiting Professor (Under JSPS fellowship), Research Institute of Life and Health Sciences,

Chubu University, Japan

2004-2012 Associate Prof., Dept. of Biochemistry & Molecular Biology, University of Rajshahi, Bangladesh

2001-2004 Assistant Prof., Dept. of Biochemistry & Molecular Biology, University of Rajshahi, Bangladesh

1998-2001 Lecturer, Dept. of Biochemistry & Molecular Biology, University of Rajshahi, Bangladesh

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Professional Honors, Awards and Fellowships Awards

Fellowship

Editorial Position

2017 Dean’s Award, from the Faculty of Science, University of Rajshahi, Bangladesh in

recognition of the outstanding achievement in research

2014 Dean’s Award, from the Faculty of Science, University of Rajshahi, Bangladesh in

recognition of the outstanding achievement in research

2014 Institute for Developing Science & Health Initiatives (ideSHi) Award for the outstanding

contribution in the research, Dhaka, Bangladesh

2007 Bangladesh Academy of Sciences Gold Medal Award (junior group) for outstanding

contribution in Biological Sciences in Bangladesh

1991 Rajshahi University Award for the best academic result in the Bachelor of Science

Examination from the Department of Biochemistry and Molecular Biology, University of

Rajshahi, Bangladesh

1992 Rajshahi University Award for the best academic result in the Master of Science

Examination from the Department of Biochemistry and Molecular Biology, University of

Rajshahi, Bangladesh

1998-2003 Monbusho Scholarship for the Ph.D level research in Nagoya University, Japan

2004-2005 Tokyo Biochemical Research Foundation (TBRF) Fellowship for the Asian young

Scientist, Japan

2005-2007 Japanese Society for the Promotion of Science (JSPS) fellowship, Japan

2011-2012 Commonwealth Staff Fellowship, UK

2021-2022 Nominated for Fulbright Visiting Program and the program is expected to be

started on 1 Sept. 2021

2015-present Environmental Health and Preventive Medicine

2015-present Academic editor, PLOS ONE

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Journal Reviewers

Environment International, Environmental Pollution, Science of The Total Environment, Chemosphere, Plos One etc.

Society Membership

Member of Bangladesh JSPS (Japan Society for the Promotion of Science) Alumni Association

Life member of the Bangladesh Society for Biochemistry and Molecular Biology

Former member of Japanese Society of Hygiene

Training program

Short-term skill transfer program in NIES Japan, (August 25, 2014 to September 5, 2014)

Conference/seminar attended 1. 46th Annual Meeting of the Japanese Society of Toxicology (JSOT) 26-28 June, 2019,

Tokushima, Japan (invited speaker) 2. The Fourth Forum on Signaling Pathways and Non-coding RNAs in Carcinogenesis, Prevention

and Therapy of Malignant Tumors. May 24, 2019, Medical Education and Research Facility (MERF) at The University of Iowa, USA. (Invited speaker)

3. The 24th Symposium of the Japanese Arsenic Society held in Kumamoto, Japan. Nov. 23-25, 2018 (Invited speaker).

4. 25th Annual Meeting of the Japanese Society of Immunotoxicity held in Tsukuba, Japan, September 18-10, 2018 ( Invited speaker).

5. International conference on “Translational Research in Biochemistry for Better Life and Sustainable Development” arranged by Department of Biochemistry and Molecular Biology, University of Rajshahi, Bangladesh, September 06, 2018 (Invited speaker).

6. International conference arranged by Applied Nutrition and Food Technology, Islamic University Kushtia Bangladesh, May 6, 2017 (Invited speaker).

7. Symposium arranged by Environmental Health and Preventive Medicine held in Miyazaki, Japan, 27 March, 2017(Invited speaker).

8. 6th International Congress on Arsenic in the Environment Arsenic Research and Global Sustainability, held in Stockholm, Sweden, 19-23 June 2016 (Speaker).

9. 10th Metal Bioscience Meeting in Japan held in Nagoya, Japan, August 27-28, 2015 (Speaker) 10. Second Conference of Global Network of Bangladeshi Biotechnologists (GNOBB) held in

Dhaka, Bangladesh, January 9-10, 2015. 11. Bangladesh Society for Biochemistry and Molecular Biology- held in Dhaka, Bangladesh 2015 (Invited

speaker)

12. American Society of Microbiology Scientific meeting held icddr,b, Dhaka, Bangladesh, 2014 (Speaker)

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13. U.S-Japan Cooperative Medical Sciences Program (CMSP) and 16th International Conference on Emerging Infectious Diseases (EID) in the Pacific Rim. icddr,b, Dhaka, Bangladesh, 2014

14. Workshop at National Institute for Environmental Studies, Tsukuba, Japan, December 10, 2013, (Invited speaker)

15. Invited speaker in Tukushima Bunri University, 2013, Japan, 16. Annual conference of the Bangladesh Society of Biochemistry and Molecular Biology- held in

Chittagong, Bangladesh 2013. Key note speaker 17. Annual Congress on British Toxicology Society, Warwick University, UK, 2012 (Poster

presentation) 18. Invited speaker in Skovde University, Sweden, 2011

19. International Symposium organized by Bangladesh Society for Biochemistry and Molecular Biology- held in Dhaka, Bangladesh 2010

20. Invited speaker in Tukushima Bunri University, 2009, Japan. 21. Young Scientists Congress organized by Bangladesh Academy of Sciences, Dhaka, Bangladesh,

2009. 22. Annual Conference of Japanese Society of Hygiene: held in Osaka, Japan, 2007 23. Conference on pigment cell research: held in Nagano, Japan, 2006 24. Annual Conference of Japanese Society of Hygiene: held in Yamaguchi, Japan 2006 as an

invited speaker. 25. Annual Conference of Japanese Society of Immunology: held in Osaka, Japan , 2001 26. 11th International Congress of Immunology: held in Stockholm, Sweden, 2001 27. Annual Conference of Japanese Society of Immunology: held in Sendai, Japan , 2000 28. Annual Conference of Japanese Society of Immunology: held in Kyoto, Japan , 1999 29. International Symposium for oxidative Stress, Redox Regulation and Signal Transduction, Clinical

implications: held in Kyoto, Japan, 1999

Grant Supports

2013-2015 TWAS (Third World Academy of Sciences) research grant

2012-2013 MOST (Ministry of Science and Technology, Bangladesh Government) grant

2010-2011 TWAS research grant

2009-2010 BMRC grant

2008-2009 TWAS research grant

2007-2008 MOSICT grant

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PhD Supervision

Eight fellows have received their PhD degrees under my supervision.

Supervision of Master’s level research

Several master levels students completed their thesis.

Publication List

1. Rahman A, Islam MS, Tony SR, Siddique AE, Mondal V, Hosen Z, Islam Z, Hossain MI,

Rahman M, Anjum A, Paul SK, Hossen F, Sarker MK, Hossain S, Salam KA, Haque A, Hoque

MA, Saud ZA, Xin L, Sumi D, Himeno S, Hossain K (2021). T helper 2-driven immune

dysfunction in chronic arsenic-exposed individuals and its link to the features of allergic asthma.

Toxicol Appl Pharmacol. 420:115532. doi: 10.1016/j.taap.2021.115532.

2. Ali N, KA Fariha, F Islam, MA Mishu, Mohanto NC, Hosen MJ, Hossain K (2021). Exposure to air

pollution and COVID‐19 severity: A review of current insights, management, and challenges.

Integr Environ Assess Manag. 20: 10.1002/ieam.4435. doi: 10.1002/ieam.4435

3. Ali N, Hossain K (2020). Liver injury in severe COVID-19 infection: current insights and

challenges. Expert Rev Gastroenterol Hepatol. 14:879-884.

doi: 10.1080/17474124.2020.1794812

4. Banna HU, Anjum A, Biswas S, Mondal V, Siddique AE, Roy AK, Nikkon F, Haque A, Himeno

S, Salam KA, Hossain K, Saud ZA (2021). Parental Lead Exposure Promotes

Neurobehavioral Disorders and Hepatic Dysfunction in Mouse Offspring. Biol Trace Elem

Res. Apr 8. doi: 10.1007/s12011-021-02709-y.

5. M.A. Sayem, T. Ahmed, M.G. Hossain, M.K. Hossain and Z.A. Saud (2021) Factors associated

with multidrug resistant tuberculosis in Rajshahi division, Bangladesh: A cross sectional study.

Human Biology Review, 10, 50-70.

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6. Sayem MA, Hossain MG, Ahmed T, Hossain K, Saud ZA, (2020). Effect of Nutritional

Support on Treatment of Multi-Drug Resistant Tuberculosis in Rajshahi Division, Bangladesh.

Journal of Tuberculosis Research, 8, 223-236.

7. Mondal V, Hosen Z, Hossen F, Siddique AE,Tony SR, Islam Z, Islam MS, Hossain S,Islam K,

Sarker MK, Hasibuzzaman MM, Liu LZ, Jiang BH, Hoque MM, Saud ZA, Xin L, Himeno S,

Hossain K(2020). Arsenic exposure-related hyperglycemia is linked to insulin resistance

with concomitant reduction of skeletal muscle mass. Environment International.

doi.org/10.1016/j.envint.2020.105890

8. Siddique AE, Rahman M, Hossain MI, Karim Y, Hasibuzzaman MM, Biswas S, Islam MS,

Rahman A, Hossen F, Mondal V, Banna HU, Huda N, Hossain M, Sultana P, Nikkon F, Saud

ZA, Haque A, Nohara K, Xin L, Himeno S, Khaled Hossain (2020). Association between

chronic arsenic exposure and the characteristic features of asthma. Chemosphere. doi:

10.1016/j.chemosphere.

9. Yeasir Karim, Abu Eabrahim Siddique, Faruk Hossen, Mizanur Rahman, Victor Mondal,

Hasan Ul Banna, M M Hasibuzzaman, Zubaer Hosen, Md Shofikul Islam, Md

Khalequzzaman Sarker, Farjana Nikkon, Zahangir Alam Saud, Lian Xin, Seiichiro Himeno,

Khaled Hossain (2019). Dose-dependent relationships between chronic arsenic exposure

and cognitive impairment and serum brain-derived neurotrophic factor. Environment

International. PMID: 31352261 DOI: 10.1016/j.envint.2019.105029

10. Sudip Kumar Paul, Md Shofikul Islam, M M Hasibuzzaman, Faruk Hossain, Adiba Anjum,

Zahangir Alam Saud, Md Mominul Haque, Papia Sultana, Azizul Haque, Klara Biljana Andric,

Aminur Rahman, Md Rezaul Karim, Abu Eabrahim Siddique, Yeasir Karim, Mizanur Rahman,

Hideki Miyataka, Lian Xin, Seiichiro Himeno, Khaled Hossain (2019). Higher Risk of

Hyperglycemia With Greater Susceptibility in Females in Chronic Arsenic-Exposed

Individuals in Bangladesh. Sci Total Environ, 668, 1004-1012. DOI:

10.1016/j.scitotenv.2019.03.029.

11. Sheta Biswas, Adiba Anjum, Hasan Ul Banna, Mizanur Rahman, Abu Eabrahim

Siddique, Yeasir Karim , Farjana Nikkon , Azizul Haque , Khaled Hossain, Zahangir Alam

Saud(2019). Manganese attenuates the effects of arsenic on neurobehavioral and

biochemical changes in mice co-exposed to arsenic and manganese. Environmental

Science and Pollution Research. 26:29257-29266, 2019.

12. Md. Sajib Al Reza, Md. Mahmudul Hasan, Md. Kamruzzaman, Md. Imam Hossain, Md. Abu

Zubair, Luthfunnesa Bari, Md. Zainul Abedin, Md. Abu Reza, Khandaker Md.

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Khalid‐ Bin‐ Ferdaus, Kazi Md. Faisal Haque, Khairul Islam, Mahtab Uddin Ahmed, Md.

Khaled Hossain (2019). Study of a common azo food dye in mice model: Toxicity reports

and its relation to carcinogenicity. Food Sci Nutr., 667–677. doi: 10.1002/fsn3.906

13. Sheta Biswas, Hasan Ul Banna 1, Momotaj Jahan, Adiba Anjum, Abu Eabrahim Siddique,

Apurba Roy, Farjana Nikkon, Kazi Abdus Salam, Azizul Haque, Seiichiro Himeno, Khaled

Hossain, Zahangir Alam Saud (2019). In vivo evaluation of arsenic-associated behavioral

and biochemical alterations in F 0 and F 1 mice. Chemosphere. doi:

10.1016/j.chemosphere.2019.125619.

14. Anjum A, Biswas S, Rahman M, Rahman A, Siddique AE, Karim Y, Aktar S, Nikkon F, Haque

A, Himeno S, Hossain K, Saud ZA. (2019). Butyrylcholinesterase-a potential plasma

biomarker in manganese-induced neurobehavioral changes.Environ Sci Pollut Res Int. doi:

10.1007/s11356-018-04066-1.

15. Tanu T, Anjum A1, Jahan M, Nikkon F, Hoque M, Roy AK, Haque A, Himeno S, Hossain K,

Saud ZA. (2018). Antimony-Induced Neurobehavioral and Biochemical Perturbations in Mice.

Biol Trace Elem Res. doi: 10.1007/s12011-018-1290-5.

16. Ali N, Hossain K, Gisela H. Degen (2018). Blood plasma biomarkers of citrinin and

ochratoxin A exposure in young adults in Bangladesh. Mycotoxin Res. 34:59–67.

doi.org/10.1007/s12550-017-0299-5

17. Barai M, Ahsan N, Paul N, Hossain K, Abdur Rashid M, Kato M, Ohgami N, Azim Akhand A

(2017).Amelioration of arsenic-induced toxic effects in mice by dietary supplementation of

Syzygium cumini leaf extract.Nagoya J Med Sci.79:167-177. doi:

10.18999/nagjms.79.2.167.

18. Hasibuzzaman MM, Hossain S, Islam MS, Rahman A, Anjum A, Hossain F, Mohanto NC,

Karim MR, Hoque MM, Saud ZA, Miyataka H, Himeno S, Hossain K (2017). Association

Between Arsenic Exposure and Soluble Thrombomodulin: A Cross Sectional Study in

Bangladesh. PLOS ONE. 12:e0175154.

19. Hossain K, Suzuki T, Hasibuzzaman MM, Islam MS, Rahman A, Paul SK, Tanu T, Hossain

S, Saud ZA, Rahman M, Nikkon F, Miyataka H, Himeno S, Nohara K (2017). Chronic

exposure to arsenic, LINE-1 hypomethylation, and blood pressure: a cross-sectional study in

Bangladesh. Environ Health.7:16.

20. Ali N, Blaszkewicz M, Alim A, Hossain K, Degen GH (2016). Urinary biomarkers of

ochratoxin A and citrinin exposure in two Bangladeshi cohorts: follow-up study on regional

and seasonal influences. ArchToxicol. 90:2683-2697.

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21. Ali N, Blaszkewicz M, Hossain K, Degen GH (2016). Determination of aflatoxin M1 in urine

samples indicates frequent dietary exposure to aflatoxin B1 in the Bangladeshi population.

Int J Hyg Environ Health. S1438-4639:30237-1.

22. Aktar S, Jahan M, Alam S, Mohanto NC, Arefin A, Rahman A, Haque A, Himeno S, Hossain

K, Saud ZA (2016). Individual and Combined Effects of Arsenic and Lead on Behavioral and

Biochemical Changes in Mice. Biol Trace Elem Res. doi: 10.1007/s12011-016-0883-0.

23. Islam MS, Mohanto NC, Karim MR, Aktar S, Hoque MM, Rahman A, Jahan M, Khatun R,

Aziz A, Salam KA, Saud ZA, Hossain M, Rahman A, Mandal A, Haque A, Miyataka H,

Himeno S, Hossain K (2015). Elevated concentrations of serum matrix metalloproteinase-2

and -9 and their associations with circulating markers of cardiovascular diseases in chronic

arsenic-exposed individuals. Environ Health.14:92.

24. Ali N, Hossain K, Blaszkewicz M, Rahman M, Mohanto NC, Alim A, Degen GH (2015).

Occurrence of aflatoxin M1 in urines from rural and urban adult cohorts in Bangladesh. Arch

Toxicol. 90:1749-55.

25. Rahman A, Nahar N, Nawani NN, Jass J, Hossain K, Saud ZA, Saha AK, Ghosh S, Olsson

B, Mandal A (2015). Bioremediation of hexavalent chromium (VI) by a soil borne bacterium,

Enterobacter cloacae B2-DHA. J Environ Sci and Health Part A. 50:1136-1147.

26. Noman ASM, Dilruba S, Mohanto NC, Rahman L, Khatun Z, Riad W, Mamun AA, Alam S,

Aktar S, Chowdhury S, Saud ZA, Rahman Z, Hossain K, Haque A (2015). Arsenic-Induced

Histological Alterations in Various Organs of Mice. J Cytol Histol. 6:323.

27. Rahman M, Mamun AA, Karim MR, Islam K, Amin AA, Hossain S, Hossain MI, Saud ZA,

Noman ASM, Miyataka H, Himeno S, Hossain K (2015). Associations of total arsenic in

drinking water, hair and nails with serum vascular endothelial growth factor in arsenic-

endemic individuals in Bangladesh. Chemosphere. 120:336-342.

28. Ali N, Blaszkewicz M, Mohanto NC, Rahman M, Alim A, Hossain K, Degen GH (2015). First

results on citrinin biomarkers in urines from rural and urban cohorts in Bangladesh.

Mycotoxin Research. 31:9-16.

29. Huda N, Hossain S, Rahman M, Karim MR, Islam K, Mamun AA, Hossain MI, Mohanto NC,

Alam S, Aktar S, Arefin A, Ali N, Salam KA, Aziz A, Saud ZA, Miyataka H, Himeno S,

Hossain K (2014). Elevated levels of plasma uric acid and its relation to hypertension in

arsenic-endemic human individuals in Bangladesh. Toxicology and Applied

Pharmacology. 281:11–18.

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30. Rahman A, Nahar N, Nawani NN, Jass J, Desale P, Kapadnis BP, Hossain K, Saha AK,

Ghosh S, Olsson B, Mandal A (2014). Isolation and characterization of a Lysinibacillus strain

B1-CDA showing potential for bioremediation of arsenics from contaminated water. Journal

of environmental science and health. Part A, Toxic/hazardous substances &

environmental engineering. 49:1349-1360.

31. Ali N, Blaszkewicz M, Manirujjaman M, Perveen R, Nahid AA, Mahmood S, Rahman M,

Hossain K, Degen GH (2014). Biomonitoring of ochratoxinA in blood plasma and exposure

assessment of adult students in Bangladesh. Molecular Nutrition & Food Research.

58:2219-2225.

32. Reza T, AktarS, Amin HA, Rahman M, Arefin A, Mohanto NC, Alam S, Mamun AA, Habib

MA, Asafudullah SM, Hossain K, Saud ZA. (2014). In vivo analysis of toxic effect of

hydrose indiscriminately used in food preparations in Bangladesh. Asian Pacific Journal of

Tropical Biomedicine. 4:884-889.

33. Sheikh A, Yeasmin F, Agarwal S, Rahman M, Islam K, Hossain E, Hossain S, Karim MR,

Nikkon F, Saud ZA, and Hossain K (2014). Protective effects of Moringaoleifera Lam. leaves

against arsenic-induced toxicity in mice. Asian Pacific Journal of Tropical Biomedicine.

4:353-358.

34. Nahar N, Rahman A, Moś M, Warzecha T, Ghosh S, Hossain K, Nawani NN, and Mandal A

(2014). In silico and in vivo studies of molecular structures and mechanisms of AtPCS1

protein involved in binding arsenite and/or cadmium in plant cells. Journal of Molecular

Modeling. 20:2104.

35. Karim MR, Rahman M, Islam K, Mamun AA, Hossain S, Hossain E, Aziz A, Yeasmin F,

Agarwal S, Hossain MI, Saud ZA, Nikkon F, Hossain M, Mandal A, Jenkins RO, Haris PI,

Miyataka H, Himeno S, Hossain K (2013). Increases in oxidized low-density lipoprotein and

other inflammatory and adhesion molecules with a concomitant decrease in high-density

lipoprotein in the individuals exposed to arsenic in Bangladesh. Toxicological Sciences.

135:17-25.

36. Ali Y, Islam MS, Alam AHMK, Rahman MAA, Mamun A, Hossain K, Hossain AKMM, Parvin

MS, Rashid M (2013). Inhibitory Effects of Nigella sativa Seed Extract on Adrenaline-Induced

Dyslipidemia and Left Ventricular Hypertrophy in Rats. Journal of Scientific Research. 5:2.

37. Sarker RSJ, Ahsan N, Hossain K, Ghosh PK, Akhand AA (2012). Reduction of Sodium

Arsenite-Mediated Adverse Effects in Mice using Dietary Supplementation of Water Hyacinth

(Eichorniacrassipes) Root Powder. Avicenna Journal of Medical Microbiology. 4:148-154.

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38. Hossain E, Islam K, Yeasmin F, Karim MR, Rahman M, Agarwal S, Hossain S, Aziz A,

Mamun AA, Sheikh A, Haque A, Hossain MT, Hossain M, Haris PI, Ikemura N, Inoue K,

Miyataka H, Himeno S, Hossain K (2012). Elevated levels of plasma Big endothelin-1 and its

relation to hypertension and skin lesions in individuals exposed to arsenic. Toxicology and

Applied Pharmacology. 259:187-194.

39. Rahman M, Saud ZA, Hossain E, Islam K, Karim MR, Hoque MM, Yeasmin T, Nikkon F,

Mandal A, Hossain K (2012). The ameliorating effects of Zingiberzerumbet Linn.on sodium

arsenite- induced changes of blood indices in experimental mice. Life Sciences and

Medicine Research. LSMR-41.

40. Barman D, Saud ZA, Habim MR, Islam MF, Hossain K, Yeasmin T. (2011). Isolation of

cellulytic bacterial strains from soil for effective and efficient bioconversion of solid waste.

Life Sciences and Medicine Research. LSMR-25.

41. Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Yajima I, Goto Y, Ohgami N (2011). L-

cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.

Toxicology in Vitro. 25: 623-9.

42. Islam K, Haque A, Karim R, Fajol A, Hossain E, Salam KA, Ali N, Saud ZA, Rahman M,

Rahman M, Karim R, Sultana P, Hossain M, Akhand AA, Mandal A, Miyataka H, Himeno S,

Hossain K (2011). Dose-response relationship between arsenic exposure and the serum

enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study

in Bangladesh. Environmental Health. 10:64.

43. Karim MR, Salam KA, Hossain E, Islam K, Ali N, Haque A, Saud ZA, Yeasmin T, Hossain M,

Miyataka H, Himeno H, Hossain K (2010). Interaction between chronic arsenic exposure via

drinking water and plasma lactate dehydrogenase activity. Science of the Total

Environment. 409: 278-83.

44. Karim MR, Haque A, Islam K, Ali N, Salam KA, Saud ZA, Hossain E, Fajol A, Akhand AA,

Himeno S, Hossain K (2010). Protective effects of the dietary supplementation of turmeric

(Curcuma longa L.) on sodium arsenite-induced biochemical perturbation in mice.

Bangladesh Medical Research Council Bulletin. 36:82-88.

45. Ali N, Hoque MA, Haque A, Salam KA, Karim MR, Rahman A, Islam K, Saud ZA, Khalek MA,

Akhand AA, Hossain M, Mandal A, Karim MR, Miyataka H, Himeno S, Hossain K (2010).

Association between arsenic exposure and plasma cholinesterase activity: a population

based study in Bangladesh. Environmental Health. 9:36.

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46. Kumasaka MY, Yajima I, Hossain K, Iida M, Tsuzuki T, Ohno T, Takahashi M, Yanagisawa

M, Kato M. (2010). A novel mouse model for de novo Melanoma. Cancer Research. 70:24-

9.

47. Kato M, Takeda K, Hossain K, Thang ND, Kaneko Y, Kumasaka M, Yamanoshita O,

Uemura N, Takahashi M, Ohgami N, Kawamoto Y (2010). A redox-linked novel pathway for

arsenic-mediated RET tyrosine kinase activation. Journal of Cellular Biochemistry.

110:399-407.

48. Nikkon F, Saud ZA, Hossain K, Parvin MS, Haque M (2009). Larvicidal Effects of Stem and

Fruits of Durantarepens Against the Mosquito Culex Quinquefasciatus. International

Journal of Pharm. Tech Research. 1:1709-13.

49. Hossain K, Kawamoto Y, Hamada M, Akhand AA, Yanagishita T, Hoque MA, Tsuboi H, Kato

M, Nakashima I (2009). 1,4-butanediyl-bismethanethiosulfonate (BMTS) induces apoptosis

through reactive oxygen species-mediated mechanism. Journal of Cellular Biochemistry.

108:1059-65.

50. Kato M, Hossain K, Iida M, Sato H, Uemura N, Goto Y (2008). Arsenic enhances matrix

metalloproteinase-14 expression in fibroblasts. Journal of Toxicology Environmental

Health Part A. 71:1053-55.

51. Noman ASM, Islam MS, Alam NS, Hossain K (2008). High Frequency Induction of Multiple

Shoots from Nodal Explants of Vitexnegundousing Silver Nitrate. International Journal of

Agriculture and Biology. 10:633-37.

52. Kato M, Ohgami N, Kawamoto Y, Tsuzuki T, Hossain K, Yanagishita T, Ohshima Y, Tsuboi

H, Yamanoshita O, Matsumoto Y, Takahashi M, Nakashima I (2007). Protective Effect of

Hyperpigmented Skin on UV-Mediated Cutaneous Cancer Development. Journal of

Investigative Dermatology. 127:1244-9.

53. Kato M, Takeda K, Kawamoto Y, Hossain K, Ohgami N, Yanagishita T, Ohshima Y, Kato Y,

Ohgami K, Yamamori T, Tateyama K, Yamanoshita O (2007). Ultraviolet Irradiation-Mediated

Malignant Melanoma Induction with RET Tyrosine kinase Activation. Japanese Journal of

Hygiene. 62:3-8.

54. Kato M, Takeda K, Kawamoto Y, Tsuzuki T, Kato Y, Ohno T, Hossain K, Iftakhar-E-Khuda I,

Ohgami N, Isobe K, Takahashi M, Nakashima I (2006). Novel Hairless RET-Transgenic

Mouse Line with Melanocytic Nevi and Anagen Hair Follicles. Journal of Investigative

Dermatology. 126:2547-50.

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55. Kato M, Takeda K, Kawamoto Y, Hossain K, Kato Y, Yanagishita T, Oshima Y, Ohgami N,

Ogami K, Tajima S, Yamanoshita O, Iftakhar-E-Khuda I, Matsumoto Y (2006). Analysis of

mechanism of melanoma tumorigenesis. Cell (Tokyo). 38:573-77.

56. Kato M, Takeda K, Kawamoto Y, Tsuzuki H, Hossain K, Tamakoshi A, Kunisada T,

Kambayashi Y, Ogino K, Suzuki H, Takahashi M, Nakashima I (2004). c- Kit-targeting

immunotherapy for hereditary melanoma in a mouse model. Cancer Research. 64:801-6.

57. Tsuboi H, Hossain K, Akhand AA, Takeda K, Du J, Rifa`i M, Dai Y, Hayakawa A, Suzuki H,

Nakashima I (2004). Paeoniflorin induces apoptosis of lymphocytes through a redox-linked

mechanism. Journal of Cellular Biochemistry. 93:162-72.

58. Suzuki H, Wu J, Hossain K, Ohhata T, Du J, Akhand AA, Hayakawa A, Kimura H, Hagiwara

M, Nakashima I (2003). Involvement of MKK6 in TCR alphabeta (int) CD69lo: a target

population for apoptotic cell death in thymocytes. The FASEB Journal. 17:1538-40.

59. Kajiguchi T, Yamamoto K, Hossain K, Akhand AA, Nakashima I, Naoe T, Saito H, Emi N

(2003). Sustained activation of c-jun-terminal kinase (JNK) is closely related to arsenic

trioxide-induced apoptosis in an acute myeloid leukemia (M2)-derived cell line, NKM-1.

Leukemia. 17:2189-95.

60. Hossain K, Akhand AA, Kawamoto Y, Du J, Takeda K, Wu J, Yoshihara M, Tsuboi H, Kato

M, Suzuki H, Nakashima I (2003). Caspase activation is accelerated by the inhibition of the

arsenite-induced, membrane rafts-dependent Akt activation. Free Radical Biology &

Medicine. 34:598-606.

61. Wu J, Suzuki H, Akhand AA, Zhou YW, Hossain K, Nakashima I (2002). Modes of activation

of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in

human leukemia cells. Cellular Signaling. 14:509-15.

62. Akhand AA, Ikeyama T, Akazawa S, Kato M, Hossain K, Takeda K, Suzuki H, Takahashi M,

Nakashima I (2002). Evidence of both extra- and intracellular cysteine targets of protein

modification for activation of RET kinase. Biochemical and Biophysical Research

Communications. 292:826-31.

63. Akhand AA, Du J, Liu W, Hossain K, Miyata T, Nagase F, Kato M, Suzuki H, Nakashima I

(2002). Redox-linked cell surface-oriented signaling for T-cell death. Antioxidant Redox

Signaling. 4:445-54.

64. Nakashima I, Kato M, Akhand AA, Suzuki H, Takeda K, Hossain K, Kawamoto Y (2002).

Redox-linked signal transduction pathways for protein tyrosine kinase activation. Antioxidant

Redox Signaling. 4:517-31.

13

65. Dai Y, Kato M, Takeda K, Kawamoto Y, Akhand AA, Hossain K, Suzuki H, Nakashima I

(2001). T-cell-immunity-based inhibitory effects of orally administered herbal medicine juzen-

taiho-to on the growth of primarily developed melanocytic tumors in RET-transgenic mice.

Journal of Investigative Dermatology. 117:694-701.

66. Wu J, Suzuki H, Zhou YW, Liu W, Yoshihara M, Kato M, Akhand AA, Hayakawa A, Takeuchi

K, Hossain K, Kurosawa M, Nakashima I (2001). Cepharanthine activates caspases and

induces apoptosis in Jurkat and K562 human leukemia cell lines. Journal of Cellular

Biochemistry. 82:200-14.

67. Akhand AA, Hossain K, Mitsui H, Kato M, Miyata T, Inagi R, Du J, Takeda K, Kawamoto Y,

Suzuki H, Kurokawa K, Nakashima I (2001). Glyoxal and methylglyoxal trigger distinct signals

for map family kinases and caspase activation in human endothelial cells. Free Radical

Biology & Medicine. 31:20-30.

68. Takeuchi K, Kato M, Suzuki H, Akhand AA, Wu J, Hossain K, Miyata T, Matsumoto Y,

Nimura Y, Nakashima I (2001). Acrolein induces activation of the epidermal growth factor

receptor of human keratinocytes for cell death. Journal Cellular Biochemistry. 81:679-88.

69. Akhand AA, Hossain K, Kato M, Miyata T, Du J, Suzuki H, Kurokawa K, Nakashima I (2001).

Glyoxal and methyglyoxal induce aggregation and inactivation of ERK in human endothelial

cells. Free Radical Biology & Medicine. 31:1228-35.

70. Kato M, Liu W, Akhand AA, Hossain K, Takeda K, Takahashi M, Nakashima I (2000).

Ultraviolet radiation induces both full activation of Ret kinase and malignant melanocytetumor

promotion in RFP-RET-transgenicmice. Journal of Investigative Dermatology. 115:1157-

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71. Kato M, Iwashita T, Akhand AA, Liu W, Takeda K, Takeuchi K, Yoshihara M, Hossain K, Wu

J, Du J, Oh C, Kawamoto Y, Suzuki H, Takahashi M, Nakashima I (2000). Molecular

mechanism of activation and super activation of Ret tyrosine kinases by ultraviolet light

irradiation. Antioxidant Redox Signaling. 2:841-9.

72. Hossain K, Akhand AA, Kato M, Du J, Takeda K, Wu J, Takeuchi K, Liu W, Suzuki H,

Nakashima I. (2000). Arsenite Induces Apoptosis of Murine T lymphocytes Through

Membrane Raft-linked Signaling for Activation c-Jun Amino–Terminal Kinase. Journal of

Immunology. 165:4290-97.

73. Nakashima I, Kato M, Akhand AA, Du J, Liu W, Dai Y, Suzuki H, Senga T, Hamaguchi M,

Iawashita T, Takahashi M, Miyata T, Hossain K, Takeda K, Wu J, Takeuchi K, Yoshihara M,

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Kawamoto Y (2000). Chemical reaction-mediated alternative signalling pathway in cells of the

immune system. Current Trends in Immunology. Vol.3.

74. Nakashima I, Kato M, Akhand AA, Kato M, Du J, Liu W, Hossain K, Suzuki H, Wu J, Takeda

K, Kakeuchi K, Yoshihara M (1999). Oxidative Stress and signal transduction in the immune

system. Recent Research Developments in Immunology. 1:283-96.

Book Chapter

1. Khaled Hossain, M.M. Hasibuzzaman, Seiichiro Himeno (2018). Characteristicsand Health

Effects of Arsenic Exposure in Bangladesh. Arsenic Contamination in Asia. Springer-Nature.