CURRICULUM VITAE NAME: Gerhard H. Giebisch, M.D. BORN: Vienna, Austria January 17, 1927 MARRIED: Ilse Riebeth, 1952 Children: 2 CITIZENSHIP: American Citizenship, January 1962 EDUCATION: Elementary and High School, Vienna, Austria M.D., University of Vienna Medical School, 1951 PROFESSIONAL EXPERIENCE: 2004- Sterling Professor Emeritus of Cellular & Molecular Physiology, Yale Univ. School of Medicine 1970- 2004 Sterling Professor of Cellular & Molecular Physiology, Yale University, School of Medicine 1968-1973 Professor and Chairman, Yale University School of Medicine 1965-1968 Professor of Physiology, Cornell University Medical College 1960-1965 Associate Professor of Physiology, Cornell University Medical College 1957-1960 Assistant Professor of Physiology, Cornell University Medical College 1956-1957 Assistant Professor of Pharmacology, University of Vienna Medical School 1955-1956 Instructor in Physiology, Cornell University Medical College 1953-1954 Fellow, Physiology, Cornell University Medical College 1952-1953 Intern, Milwaukee Hospital 1951 Instructor of Pharmacology, University of Vienna Medical School HONORS: Gottschalk Lecturer, 2007 J. Peters Award, 2006 Edward N. Gibbs Memorial Award, NY Academy of Medicine, 2004 Honorary Doctorate, University of Connecticut, 2004 Donald W. Seldin Distinguished Lectureship, National Kidney Foundation, 2004 Honorary Member, International Society of Nephrology, 2001 Honorary Member, The Physiological Society (London) Honorary Doctorate, University of Vienna, 1997 Honorary Member, American Soc. of Nephrology, 1995 Berliner Award, American Soc. of Physiology, 1994 Walter B. Cannon Memorial Lecturer, 1993 Bayliss-Starling Prize Lecturer, 2004 A.N.Richards Award, Int. Soc. of Nephrology, 1993 Distinguished Service Award, Association of Chairmen of Departments of Physiology, 1992 Honorary Doctorate, University of Lausanne, 1991 Ernst Jung-Preis für Medizin, 1990 Volhard Medal, German Nephrological Society, 1988 Deutsche Akademie der Naturforscher Leopoldina, 1988
Transcript
CURRICULUM VITAE NAME: Gerhard H. Giebisch, M.D.
BORN: Vienna, Austria January 17, 1927 MARRIED: Ilse Riebeth, 1952 Children: 2 CITIZENSHIP: American Citizenship, January 1962 EDUCATION: Elementary and High School, Vienna, Austria M.D., University of Vienna Medical School, 1951 PROFESSIONAL EXPERIENCE: 2004- Sterling Professor Emeritus of Cellular & Molecular Physiology, Yale Univ. School
of Medicine 1970- 2004 Sterling Professor of Cellular & Molecular Physiology, Yale University, School of
Medicine 1968-1973 Professor and Chairman, Yale University School of Medicine 1965-1968 Professor of Physiology, Cornell University Medical College 1960-1965 Associate Professor of Physiology, Cornell University Medical College 1957-1960 Assistant Professor of Physiology, Cornell University Medical College 1956-1957 Assistant Professor of Pharmacology, University of Vienna Medical School 1955-1956 Instructor in Physiology, Cornell University Medical College 1953-1954 Fellow, Physiology, Cornell University Medical College 1952-1953 Intern, Milwaukee Hospital 1951 Instructor of Pharmacology, University of Vienna Medical School HONORS: Gottschalk Lecturer, 2007 J. Peters Award, 2006 Edward N. Gibbs Memorial Award, NY Academy of Medicine, 2004 Honorary Doctorate, University of Connecticut, 2004 Donald W. Seldin Distinguished Lectureship, National Kidney Foundation, 2004 Honorary Member, International Society of Nephrology, 2001 Honorary Member, The Physiological Society (London) Honorary Doctorate, University of Vienna, 1997 Honorary Member, American Soc. of Nephrology, 1995 Berliner Award, American Soc. of Physiology, 1994 Walter B. Cannon Memorial Lecturer, 1993 Bayliss-Starling Prize Lecturer, 2004 A.N.Richards Award, Int. Soc. of Nephrology, 1993 Distinguished Service Award, Association of Chairmen of Departments of Physiology, 1992 Honorary Doctorate, University of Lausanne, 1991 Ernst Jung-Preis für Medizin, 1990 Volhard Medal, German Nephrological Society, 1988 Deutsche Akademie der Naturforscher Leopoldina, 1988
President, Society of General Physiologists, 1986-1987 National Academy of Sciences, 1984 American Academy of Arts and Sciences, 1983 Distinguished Service Award, 1983 Cornell University Medical College Alumni Society Honorary Doctorate, University of Connecticut, 2004 Wellcome Visiting Professorship, 1983 Johannes Müller Medal, German Physiological Society, 1980 Council, Society of General Physiology, 1980-1982 Honorary Doctorate, University of Bern, 1979 Advisory Committee, New York Heart Association, 1978-1981 Honorary Doctorate, Uppsala University, 1977 Professor d'Honneur, University of Lausanne, 1974-1975 Faculty Scholar Award, Josiah Macy, Jr. Foundation, 1974-1975 President, American Society of Nephrology, 1971-1972 Recipient, Homer Smith Award, 1971 Executive Committee, Internatl. Nephrological Society, 1969-1981 Renal Disease and Urology Training Grant Study Section, 1970-1973 Section Editor: Kidney and Electrolyte Metabolism, American Journal of Physiology, American
Journal of Appl Physiol, 1967-1969 Editor, Physiological Reviews, 1985-l990 Associate Editor, Physiological Reviews, 1993–2000 Physiology Study Section, Natl. Institutes of Health, 1964-1969, 1982-1984 Council, National Institutes of Diabetes, Digestive Diseases & Kidney Diseases (NIDDK), l988- Council, American Physiological Society, l988-l990 Recipient of Public Health Research Career Award, 1962-1968 Established Investigator of the American Heart Assoc., 1957-1962 Honorary Member: Austrian Academy of Science Austrian Physiological and Nephrological Society Honorary Associate: Society of Physiology of Brazil Editorial Board: Pflügers Archiv, Journal of Membrane Biology, Kidney International,
Physiology, Annual Reviews Honorary Foreign Member, Brazilian National Academy of Medicine MEMBERSHIPS: American Physiological Society Biophysical Society American Society of Nephrology Harvey Society Salt and Water Club Society of Clinical Research German Nephrological Society European Academy of Sciences & Arts Society of General Physiology Austrian Nephrological Society American Society of Clinical Investigators (Honorary Membership) International Society of Nephrology (Honorary Membership)
1. Giebisch, G. and Werner, G. Die Nebennierenrindenhormone. Wiener Zeitschrift für Innere Medizin 32:481-492, 1951.
2. Giebisch, G., Klupp, H. and Rapoport, S. Quecksilberwirkung und osmotische Diurese bein
Hund. Arch. Exp. Path. und Pharmakol. 214:562-578, 1952. 3. Braunsteiner, H., Giebisch, G., Kolder, H. and Werner, G. Untersuchungen über Freisetzung und
Verteilung von adrenocorticotropem Hormon in Parabiosetieren. Arch. Exp. Path. und Pharmakol. 215:210-216, 1952.
4. Braunsteiner, H., Giebisch, G., Kolder, H. and Werner, G. Die Retention von Leukozyten in der
Lunge. Wiener Zeitschrift fur Innere Medizin 33:98-108, 1952. 5. Giebisch, G. Some newer aspects of sodium and water metabolism. Marquette Medical Review
19:70-81, 1954. 6. Giebisch, G., Lauson, H.D. and Pitts, R.F. Renal excretion and volume of distribution of various
dextrans. Am. J. Physiol. 178:168-176, 1954. 7. Giebisch, G., Berger, L. and Pitts, R.F. The extrarenal response to acute acid-base disturbances
of respiratory origin. J. Clin. Invest. 34:231-245, 1955. 8. Giebisch, G., MacLeod, M.B. and Pitts, R.F. Effect of adrenal steroids on renal tubular
reabsorption of bicarbonate. Am. J. Physiol. 183:377-386, 1955. 9. Deutsch, E., Giebisch, G., Muller, A., Scheuba, G. and Thaler, H. Die Wirkung verschiedener
Kumarine und ähnlicher Stoffe auf die Blutgerinnung und die Kapillarpermeabilität. Klinische Medizin 11:133-138, 1956.
10. Giebisch, G., MacLeod, M.B. and Kavaler, F. Renal excretion of radioiodide in the dog. Am. J.
Physiol. 187:529-535, 1956. 11. Giebisch, G. Measurements of pH, chloride and inulin concentrations in proximal tubule fluid
of Necturus. Am. J. Physiol. 185:171-174, 1956. 12. Giebisch, G., Kraupp, O., Pillat, B. and Stormann, H. Die Wirkung der Sulfationen auf das
Membranpotential der isoliert durchströmten Säugetiermuskulatur. Experientia 13:1-6, 1957. 13. Giebisch, G., Kraupp, O., Pillat, B. and Stormann, H. Der Ersatz von extracellularem
Natriumchlorid durch Natriumsulfat bzw. Saccharose und seine Wirkung auf die isoliert durchströmte Säugetiermuskulatur. Pflugers Arch. 265:220-236, 1957.
14. Giebisch, G. Renale und extrarenale Kompensation primär respiratorisch bedingter Störungen
des Elektrolythaushaltes. Wiener Klinische Wochenschrift 69:310-317, 1957.
15. Giebisch, G., Kraupp, O., Pillat, B. and Stormann, H. Einfluss der Chlorionenkonzentration auf Ruhepotential, Kalium und Milchsäurefreisetzung an der isoliert durchströmten Säugetiermuskulatur. Archiv fur Exper. Pathologie und Pharmakologie 232:314-315, 1957.
16. Giebisch, G. and Dorman, P.J. Comparative study of uptake and distribution of Hg203 given as
labelled chlormerodrin (neohydrin). Proc. Soc. Exper. Biol. and Med. 98:50-52, 1958. 17. Pillat, B., Kraupp, O., Giebisch, G. and Stormann, H. Die Abhängigkeit des elektrischen
Ruhepotentials des isoliert durchströmten Säugetiermuskels von der extracellularen Kaliumkonzentration. Pflugers Arch. 266:459-472, 1958.
18. Giebisch, G. Electrical potential measurements on single nephrons of Necturus. J. Cell. Comp.
Physiol. 51:221-239, 1958. 19. Giebisch, G. and Lozano, R. The effects of adrenal steroids and potassium depletion on the
elaboration of an osmotically concentrated urine. J. Clin. Invest. 38:843-853, 1959. 20. Giebisch, G., Windhager, E.E. and Pitts, R.F. Mechanism of urinary acidification. In: Biology
of Pyelonephritis, Boston: Little, Brown & Company, 1960, p. 277-287. 21. Giebisch, G. Measurements of electrical potentials and ion fluxes on single renal tubules.
Circulation 21:879-891, 1960. 22. Giebisch, G. Measurements of electrical potential differences on single nephrons of the
perfused Necturus kidney. J. Gen. Physiol. 44:659-678, 1961. 23. Giebisch, G. The contribution of measurements of electrical phenomena to our knowledge of
renal electrolyte transport. Prog. Cardiovasc. Dis. 3:463-482, 1961. 24. Windhager, E.E. and Giebisch, G. Micropuncture study of renal tubular transfer of sodium
chloride in the rat. Am. J. Physiol. 200:581-590, 1961. 25. Windhager, E.E. and Giebisch, G. Comparison of short-circuit current and net water movement
in single perfused proximal tubules of rat kidney. Nature 191:1205-1206, 1961. 26. Giebisch, G. Kidney, water and electrolyte metabolism. Ann. Rev. Physiol. 24:357, 1962. 27. Giebisch, G. and Windhager, E.E. Characterization of renal tubular transport of sodium and
chloride and water as studied in single nephrons. Am. J. Med. 34:1-6, 1963. 28. Giebisch, G. and Windhager, E.E. Measurement of chloride movement across single proximal
tubules of Necturus kidney. Am. J. Physiol. 204:387-391, 1963. 29. Glabman, S., Klose, R.M. and Giebisch, G. Micropuncture study of ammonium excretion in the
rat. Am. J. Physiol. 205:127, 1963.
30. Malnic, G., Klose, R.M. and Giebisch, G. Micropuncture study of renal potassium excretion in the rat. Am. J. Physiol. 206:674-686, 1964.
31. Giebisch, G., Klose, R.M. and Windhager, E.E. Micropuncture study of hypertonic sodium
chloride loading in the rat. Am. J. Physiol. 206:687-693, 1964. 32. Giebisch, G., Klose, R.M., Malnic, G., Sullivan, W.J. and Windhager, E.E. Sodium movement
across single perfused proximal tubules of rat kidneys. J. Gen. Physiol. 47:1175-1194,1964. 33. Giebisch, G. and Windhager, E.E. Renal tubular transfer of sodium, chloride and potassium.
Am. J. Med. 36:643, 1964. 33a. Strickler, J.C., Thompson, D.D., Klose, R.M. and Giebisch, G. Micropuncture Study of
inorganic phosphate excretion in the rat. J. Clin. Invest. 43: 1596-1607, 1964.
34. Windhager, E.E. and Giebisch, G. Electrophysiology of the nephron. Physiol.Rev. 45:214-244, 1965.
35. Giebisch, G. Studien zum renalen Elektrolyttransport am Einzelnephron. Wiener Klinische
Wochenschrift 770:339-344, 1965. 36. Giebisch, G. Studien zur renalen Kaliumausscheidung. Med. Welt 20:1-20, 1965. 37. Hierholzer, K., Wiederholt, M., Holzgreve, H., Giebisch, G., Klose, R.M. and Windhager, E.E.
Micropuncture study of renal transtubular concentration gradients of sodium and potassium in adrenalectomized rats. Pflugers Arch. 285:193-210, 1965.
38. Giebisch, G., Windhager, E.E. and Malnic, G. Renal control of sodium and potassium of body
fluids. In: Proceedings of the XXIIIrd International Congress of Physiological Sciences, Tokyo; Excerpta Medica International Congress Series, 1965, p. 167-175.
39. Giebisch, G. Effect of ionic substitutions on distal transtubular potential differences of rat
kidney. In: Proceedings of the XXIII International Congress of Physiological Sciences, Tokyo; Excerpta Medica International Congress Series, 1965, p. 560-568.
40. Giebisch, G. and Windhager, E.E. Renal control of sodium in body fluids. Jap. J. Nephrol. 8:1-
13, 1966. 40a. Giebisch, G. Use of micropuncture techniques in the study of electrolyte gradients in single
nephrons. Res. on Pathogenesis of Cystic Fibrosis, 1966, p. 93-111. 41. Malnic, G., Klose, R.M. and Giebisch, G. Micropuncture study of distal tubular potassium and
sodium transport in rat nephron. Am. J. Physiol. 211:529-547, 1966. 41a. Malnic, G., Klose, R.M. and Giebisch, G. Microperfusion study of distal tubular potassium and
sodium transfer in rat kidney. Am. J. Physiol. 211:548-559, 1966.
42. Giebisch, G., Malnic, G., Klose, R.M. and Windhager, E.E. Effect of ionic substitutions on
distal potential differences in rat kidney. Am. J. Physiol. 211:560-568, 1966. 43. Windhager, E.E., Boulpaep, E.L. and Giebisch, G. Electrophysiological studies on single
nephrons. In: Third International Congress of Nephrology, edited by Schreiner, G.E. Basel, New York: S. Karger, 1967, p. 35-47.
44. Giebisch, G., Klose, R.M. and Malnic, G. Renal tubular potassium transport. In: Third Inter-
national Congress of Nephrology, edited by Schrier, G.E. Basel, New York: S. Karger, 1967, p. 62-75.
45. Giebisch, G., Klose, R.M. and Malnic, G. Renal tubular potassium transport. Bull. Swiss Acad.
Sci. 23:287-312, 1967. 46. Giebisch, G. Newer micropuncture studies on sodium transport. Bull. Swiss Acad. Sci. 23:338-
347, 1967. 47. Bahlmann, J., Giebisch, G., Ochwadt, B. and Schoeppe, W. Micropuncture study of isolated
perfused rat kidney. Am. J. Physiol. 212:77-82, 1967. 48. Landwehr, D.M., Klose, R.M. and Giebisch, G. Renal tubular sodium and water reabsorption in
the isotonic sodium chloride loaded rat. Am. J. Physiol. 212:1327-1333, 1967. 49. Wiederholt, M., Hierholzer, K., Windhager, E.E. and Giebisch, G. Microperfusion study of
fluid reabsorption in proximal tubules of the rat kidney. Am. J. Physiol. 213:809-818, 1967. 50. Giebisch, G. and Weidmann, S. Membrane currents in mammalian ventricular heart muscle
fibres using a "voltage-clamp" technique. Helv. Physiol. Acta 25:189-190, 1967. 51. Landwehr, D.M., Schnermann, J., Klose, R.M. and Giebisch, G. Effect of reduction in filtration
rate on renal tubular sodium and water transport. Am. J. Physiol. 215:687-695, 1967. 52. Giebisch, G. Some electrical properties of single renal tubule cells. J. Gen. Physiol. 51:315s-
325s, 1968. 53. Malnic, G., Mello-Aires, M. and Giebisch, G. Der Einfluss des Säure-Basen Gleichgewichtes
auf den distalen Kalium-Transport. Proc VI Symp der Gesellschaft fur Nephrologie 243-246, 1968.
54. Giebisch, G. Functional organization of proximal and distal tubular electrolyte transport.
Nephron 6:260-281, 1969. 55. Giebisch, G. and Malnic, G. The regulation of distal tubular potassium transport. In: Renal
Transport and Diuretics, edited by Thurau, K. and Jahrmärker, H. Berlin, Heidelberg, New York: Springer-Verlag, 1969, p. 123-137.
56. Giebisch, G. Some aspects of renal tubular hydrogen ion transport. Proc. 4th Int. Cong.
Nephrol., Stockholm 1:181-194, 1970. 57. Giebisch, G. Some electrical properties of mammalian distal tubules. In: Electrophysiology of
Epithelial Cells, edited by Giebisch, G. and Frömter, E. Stuttgart, New York: F.K. Schattauer Verlag, 1970, p. 149-152.
58. Giebisch, G. Renal potassium excretion. In: The Kidney: Morphology, Biochemistry, Physi-
ology, edited by Rouilles, C. and Muller, A. New York: Academic Press, 1971, p. 329-382. 59. Wiederholt, M., Sullivan, W.J., Giebisch, G., Curran, P.F. and Solomon, A.K. Potassium and
sodium transport across single distal tubules of Amphiuma. J. Gen. Physiol. 57:495-525,1971. 60. Malnic, G., Mello-Aires, M. and Giebisch, G. Potassium transport across renal distal tubules of
rat kidney during acid-base disturbances. Am. J. Physiol. 221:1192-1208, 1971. 61. Giebisch, G., Boulpaep, E.L. and Whittembury, G. Electrolyte transport in kidney cells. Proc.
Roy. Soc. Lond. B 262:175-196, 1971. 61a. Wright, F.S., Strieder, N., Fowler, N.B., and Giebisch, G. Potassium secretion by distal tubule
after potassium adaptation. Am. J. Physiol. 22l:437-448, l97l. 62. Duarte, C., Chomety, F. and Giebisch, G. The effects of amiloride, ouabain and furosemide
upon distal tubular function in the rat. Am. J. Physiol. 221:632-640, 1971. 63. Wright, F. and Giebisch, G. Glomerular filtration in single nephrons. Kidney Int. 1:201-209,
1972. 64. Malnic, G., Mello-Aires, M. and Giebisch, G. Micropuncture study of renal tubular hydrogen
ion transport during alterations of acid-base equilibrium in the rat. Am. J. Physiol. 222:147-158, 1972.
65. Giebisch, G., Diezi, J., Michoud, P. and Grandchamp, A. The effect of chronic reduction of
GFR on tubular sodium and potassium transport in control and contralaterally nephrectomized rats. In: Satellite Symposium of XXV. International Congress of Physiological Sciences, Munich, (edited by Wirz, H. and Spinelli) R. Karger, 1972, p. 89-95.
66. Malnic, G. and Giebisch, G. Some electrical properties of distal tubular epithelium in the rat.
Am. J. Physiol. 223:797-808, 1972. 67. Malnic, G., de Mello-Aires, M., de Mello, G.B. and Giebisch, G. Acidification of phosphate
buffer in cortical tubules of rat kidney. Pflügers Arch. 331:275-278, 1972. 68. Giebisch, G. Coupled ion and fluid transport in the kidney. New Engl. J. Med. 287:913-919,
1972.
68a. Malnic, G. and Giebisch, G. Mechanism of renal hydrogen ion secretion. Kidney Int. 1: 280-
296, 1972. 69. Diezi, J., Michoud, P., Aceves, J. and Giebisch, G. Micropuncture study of electrolyte transport
across the papillary collecting duct of the rat. Am. J. Physiol. 224:623-634, 1973. 70. Giebisch, G., Sullivan, L.P. and Whittembury, G. Relationship between tubular net Na
reabsorption and peritubular K uptake in the perfused Necturus kidney. J. Physiol. 230:51-74, 1973.
71. Giebisch, G. and Malnic, G. Coupled ion movement across the renal tubule. In: V. Alfred
Benzon Symposium: Transport Mechanisms in Epithelia, Copenhagen: Munksgaard, 1973, p. 537-552.
72. Giebisch, G. and Windhager, E.E. Electrolyte transport across renal tubular membranes. In:
Handbook of Physiology, (edited by Orloff, J. and Berliner, R.W.) Baltimore: Williams & Wilkins, 1973, p. 315-376.
73. Giebisch, G. Some transport properties of amphibian and mammalian nephrons. In: Compar-
ative Physiology, edited by Bolis, L., Schmidt-Nielsen, K. and Maddrell, S.H.P.: North Holland Publishing Co., 1973, p. 241-291.
73a. de Mello-Aires, M., Giebisch, G., ic, G. and Curran, P.F. Kinetics of potassium transport
across single distal tubules of rat kidney. J. Physiol. 232:47-70, 1973. 74. Green, R., Windhager, E.E. and Giebisch, G. Protein oncotic pressure effects on proximal
tubular fluid movement in the rat. Am. J. Physiol. 226:265-276, 1974. 75. Strieder, N., Khuri, R.N., Wiederholt, M. and Giebisch, G. Studies on the renal action of
ouabain in the rat. Effects in the non-diuretic state. Pflugers Arch. 349:91-107, 1974. 76. Giebisch, G. The effects of drugs on electrophysiological properties of kidney tubules. In:
Drugs and Transport Processes, (edited by Callingham, B.A.): Macmillan, 1974, p. 1-15. 77. Giebisch, G. Some recent developments in renal electrolyte transport. A.N. Richards Memorial
Lecture. In: Recent Advances in Renal Physiology and Pharmacology, (edited by Wesson, L.G. and Fanelli, G.M.) Baltimore: University Park Press, 1974, p. 125-148.
78. Green, R. and Giebisch, G. Some problems with the antimony electrode. In: Proceedings of the
Workshop on Ion Selective Microelectrodes, New York: Plenum Press, 1974, p. 43-53. 79. Whittembury, G., Diezi, F., Diezi, J. and Giebisch, G. Some aspects of proximal tubular sodium
chloride reabsorption in Necturus kidney. Kidney Int. 7:293-303, 1975.
80. Khuri, R., Strieder, N., Wiederholt, M. and Giebisch, G. The effects of flow rate and potassium intake on distal tubular potassium transfer. Am. J. Physiol. 228:1249-1261, 1975.
81. Khuri, R., Strieder, N., Wiederholt, M. and Giebisch, G. The effects of graded solute diuresis
on renal tubular sodium transport in the rat. Am. J. Physiol. 228:1262-1268, 1975. 82. Giebisch, G. Some reflections on the mechanism of renal tubular potassium transport. Yale J.
Biol. and Med. 48:315-336, 1975. 82a. Green, R. and Giebisch, G. Ionic requirements of proximal tubular sodium transport. I.
Bicarbonate and chloride. Am. J. Physiol. 229:1205-1215, 1975. 83. Green, R. and Giebisch, G. Some ionic requirements of proximal tubular sodium transport. II.
The role of hydrogen ion secretion. Am. J. Physiol. 229:1216-1226, 1975. 84. Fowler, N., Giebisch, G. and Whittembury, G. Distal tubular tracer microinjection study of
renal tubular potassium transport. Am. J. Physiol. 229:1227-1233, 1975. 84a. Giebisch, G. Renal excretion of strong electrolytes. In: Physiological and Pharmacological
Biochemistry. (Biochemistry, series one, v. 12, MTP International Review of Science.) Blaschko, H., Ed.; Kornberg, H.L. and Phillips, D.C., Consultant Eds. University Park Press, Great Britain, 1975, pp. 101-135.
85. Green, R. and Giebisch, G. Some factors influencing sodium and fluid reabsorption in vivo in
the proximal convoluted tubule of rats. In: Proceedings of the VI International Congress of Nephrology, Basel: Karger, 1976, p. 96-101.
86. Windhager, E. and Giebisch, G. Proximal sodium and fluid transport. Kidney Int. 9:121-133,
1976. 87. Giebisch, G. Effects of diuretics on renal transport of potassium. In: Methods in Pharmacology,
edited by Martinez-Maldonado, M. New York: Plenum Press, 1976, p. 121-164. 88. Diezi, J., Michoud, P., Grandchamp, A. and Giebisch, G. Effects of nephrectomy on renal salt
and water transport in the remaining kidney. Kidney Int. 10:450-462, 1976. 89. Giebisch, G. and Malnic, G. Studies on the mechanism of tubular acidification. The
Physiologist 19:511-524, 1976. 90. Mullen, T.L., Kashgarian, M., Biemesderfer, D., Giebisch, G. and Biber, T.U.L. Ion transport
and structure of urinary bladder epithelium of Amphiuma. Am. J. Physiol. 231:501-508, 1976. 91. Fowler, N., Gonzales, E., Rawlins, F.A., Giebisch, G. and Whittembury, G. Effect of hyper-
tonic urea and mannitol on distal nephron permeability. Pflugers Arch. 368:3-11, 1977.
92. Spring, K.R. and Giebisch, G. Kinetics of Na+ transport in Necturus proximal tubule. J. Gen. Physiol. 70:307-328, 1977.
93. Spring, K.R. and Giebisch, G. Tracer Na fluxes in Necturus proximal tubule. Am. J. Physiol.
232:F461-F470, 1977. 94. Giebisch, G., Malnic, G., de Mello, G., and de Mello-Aires, M. Kinetics of luminal
acidification in cortical tubules of the rat kidney. J. Physiol. 267:571-599, 1977. 95. Cassola, A.C., Giebisch, G. and Malnic, G. Mechanism and components of renal tubular
acidification. J. Physiol. 267:601-624, 1977. 96. Giebisch, G. Effects of diuretics on renal tubular potassium transport. In: Diuretics in Research
and Clinics, edited by Siegenthaler, W., Beckerhoff, R. and Vetter, W. Stuttgart: Georg Thieme, 1977, p. 71-82.
97. Giebisch, G. The distal tubular potassium transport system. In: New Aspects of Renal Function,
edited by Vogel, H.G. and Ullrich, K.J. : Excerpta Medica, 1977, p. 136-146. 98. Giebisch, G. Micropuncture techniques. In: Transport of Ions and Water in Animals, edited by
Oschman, J.L. and Wall, B.J. New York: Academic Press, 1977, p. 28-56. 99. Hayslett, J.P., Boulpaep, E.L., Kashgarian, M. and Giebisch, G. Electrical characteristics of the
mammalian distal tubule: Comparison of Ling-Gerard and macroelectrodes. Kidney Int. 12:324-331, 1977.
99a. Giebisch, G.H. and Their, S.O. Potassium: Physiological and clinical importance. In:
Directions in Cardiovascular Medicine, edited by Siegel, L., Hoechst-Roussel Pharmaceuticals, Inc., Somerville, NJ, 1977, 1-48.
100. Hayslett, J.P., Boulpaep, E.L. and Giebisch, G. Factors influencing transepithelial potential
difference in mammalian distal tubule. Am. J. Physiol. 234:F182-F191, 1978. 101. Berliner, R.W. and Giebisch, G. Body fluids and the excretion of urine. In: Physiological Basis
of Medical Practice, edited by Brobeck Baltimore: Williams & Wilkins, 1978, p. 5-80. 102. Boulpaep, E.L. and Giebisch, G. Flux measurements across renal tubular epithelium. In:
Membrane Transport Processes, edited by Hoffman, J.F. New York: Raven Press, 1978, p. 331-384.
103. Boulpaep, E.L. and Giebisch, G. Electrophysiological measurements on the renal tubule. In:
Methods in Pharmacology, edited by Martinez-Maldonado, M. New York: Plenum Press, 1978, p. 165-193.
104. Giebisch, G. Amiloride effects of distal nephron function. In: Cell Membrane Receptors of Drugs and Hormones, edited by Straub, R.W. and Bolis, L. New York: Raven Press, 1978, p. 337-342.
105. Luke, R.A., Wright, F.S., Fowler, N.S., Kashgarian, M. and Giebisch, G. Effect of potassium
depletion on renal tubular chloride transport in the rat. Kidney Int. 14:414-427, 1978. 106. Wright, F.S. and Giebisch, G. Renal potassium transport: Contributions of individual nephron
segments and populations. Am. J. Physiol. 235:F515-F527, 1978. 107. Graf, J. and Giebisch, G. Intracellular sodium activity and sodium transport in Necturus
gallbladder. J. Membrane Biol. 47:327-355, 1979. 108. Malnic, G. and Giebisch, G. Cellular aspects of renal tubular acidification. In: Membrane
Transport in Biology, edited by Giebisch, G., Tosteson, D. and Ussing, H.H. Heidelberg: Springer Verlag, 1979, p. 229-235.
109. Giebisch, G. Renal potassium transport. In: Membrane Transport in Biology, edited by
Giebisch, G., Tosteson, D. and Ussing, H.H. Heidelberg: Springer Verlag, 1979, p. 215-298. 110. Giebisch, G. and Stanton, B. Potassium transport in the nephron. Ann. Rev. Physiol. 41:241-
256, 1979. 111. Biagi, B. and Giebisch, G. Temperature dependence of transepithelial potential in isolated
perfused rabbit proximal tubules. Am. J. Physiol. 236:F302-F310, 1979. 112. Green, R., Bishop, J.H.V. and Giebisch, G. Ionic requirements of proximal tubular sodium
transport. III. Selective luminal anion substitution. Am. J. Physiol. 236:F268-F277, 1979. 113. Giebisch, G. Renal tubular control of potassium transport. Klin. Wochenschr. 57:1001-1008,
1979. 114. Giebisch, G. Micropuncture techniques. In: Transport of Ions and Water in Animals, edited by
Gupta, B.L., Moreton, R.B., Oshman, J.L. and Wall, B.J. New York: Academic Press, 1979, p. 29-55.
115. Giebisch, G. Principles of ion transport in kidney tubules. In: Comparative Physiology of
Osmoregulation in Animals, edited by Maloiy, G.M.O. New York: Academic Press, 1979, Vol. I, p. 2-82.
116. Stetson, D., Wade, J.B. and Giebisch, G. Morphological alterations in the rat medullary
collecting duct following K+ depletion. Kidney Int. 17:45-56, 1980. 117. Diezi, J., Nenninger, M. and Giebisch, G. Distal tubular function in superficial rat tubules
during volume expansion. Am. J. Physiol. 239:F228-F232, 1980.
118. Giebisch, G. and Malnic, G. Role of buffer characteristics in renal tubular acidification. In: Hydrogen Ion Transport in Epithelia, edited by Schulz, I. Amsterdam: Elsevier, 1980, p. 315-320.
119. Kubota, T., Biagi, B. and Giebisch, G. Intracellular potassium activity measurements in single
proximal tubules of Necturus kidney. In: Current Topics in Membranes and Transport. Volume 13. Cellular Mechanisms of Renal Tubular Ion Transport, edited by Boulpaep, E.L. New York: Academic Press, 1980, p. 63-72.
120. Duplinsky, T.G., Giebisch, G., Gordon, D., Granges, F., Wilcox, C.S. and Kirk, G. Renal acid
elimination by anaestheized rats during saline infusion and mineralocorticosteroid admin-istration. J. Physiol. 305:45-46, 1980.
121. Biagi, B., Gonzalez, E. and Giebisch, G. A kinetic model for ion fluxes in the isolated perfused
tubule. In: Current Topics in Membranes and Transport. Volume 13. Cellular Mechanisms of Renal Tubular Ion Transport, edited by Boulpaep, E.L. New York: Academic Press, 1980, p. 229-243.
122. Giebisch, G. and Hropot, M. Effect of diuretics on renal potassium and hydrogen ion transport.
In: Diuretica I. (edited by F. Krück and A. Schvey) Berlin-Heidelberg-New York: Springer, 1980, p. 42-52.
123. Giebisch, G. Newer aspects of renal tubular potassium transport. In: Contributions to
Nephrology. Volume 21, edited by Berlyne, G.M. Basel: S. Karger, 1980, p. 106-114. 124. Jaeger, P., Karlmark, B., Stanton, B., Kirk, R.G., Duplinsky, T. and Giebisch, G.
Micropuncture study of distal tubule activation of phosphate reabsorption in the rat. In: Phosphate and Minerals in Health and Disease, (edited by Massry, S.G., Ritz, E. and John, H.) New York-London: Plenum Press, 1980, p. 77-82.
125. Giebisch, G. Methods of localizing transport processes using micropuncture techniques:
evidence for nephron heterogeneity. J. Biochem. 12:3-8, 1980. 126. Giebisch, G. and Green, R. Anion-driven fluid movement across the proximal tubular
epithelium. In: Water Transport Across Epithelia, (edited by Ussing, H.H., Bindslev, N. and Sten-Knudsen, O. Munksgaard), Copenhagen: Alfred Benson Symposium, 1981, p. 376-392.
127. Green, R., Moriarty, R.J. and Giebisch, G. Ionic requirements of proximal tubular fluid
reabsorption. IV. Flow dependence of fluid transport. Kidney Int. 20:580-587, 1981. 128. Giebisch, G. Renal control mechanisms of potassium homeostasis. Jap. J. Nephrol. 23:859-
871, 1981. 129. Giebisch, G., Kubota, T. and O'Regan, M.G. Ion-activity measurements in renal tubular
epithelium. In: The Application of Ion-Selective Microelectrodes, (edited by T. Zeuthen): Elsevier, 1981, p. 47-60.
130. Giebisch, G., Cemerikic, D., Oberleithner, H., Guggino, W. and Biagi, B. Ion activity
measurements in single renal tubules. In: Ion Transport in Epithelia, edited by Schultz, S.G. New York: Raven Press, 1981, p. 163-180.
131. Chan, Y.L. and Giebisch, G. Relationship between sodium and bicarbonate transport in the rat
proximal convoluted tubule. Am. J. Physiol. 240:F222-F230, 1981. 132. Oberleithner, H. and Giebisch, G. Mechanism of potassium transport across distal tubular
epithelium of Amphiuma. In: Epithelial Ion and Water Transport, (edited by A.D.D. Macknight and S.P. Leader) New York: Raven Press, 1981, p. 97-105.
133. Stanton, B. and Giebisch, G. Mechanism of urinary potassium excretion. Min. Electr. Metab.
5:100-120, 1981. 134. Giebisch, G., Berliner, R.W. and Malnic, G. Renal transport and control of potassium excre-
tion. In: The Kidney, Philadelphia: Saunders, 1981, p. 408-439. 135. Graf, J., Lewis, S.A. and Giebisch, G. On the effects of Amphotericin B and ouabain on the
electrical potentials of Necturus gallbladder. J. Membrane Biol. 60:167-169, 1981. 136. Biagi, B., Kubota, T., Sohtell, M. and Giebisch, G. Intracellular potentials in rabbit proximal
tubules perfused in vitro. Am. J. Physiol. 240:F200-F210, 1981. 137. Biagi, B.A., Sohtell, M. and Giebisch, G. Intracellular potassium activity in the rabbit proximal
straight tubule. Am. J. Physiol. 241:F677-F686, 1981. 138. Stanton, B.A., Biemesderfer, D., Wade, J.B. and Giebisch, G. Structural and functional study
of the rat distal nephron: Effects of potassium adaptation and depletion. Kidney Int. 19:36-48, 1981.
139. Giebisch, G. Problems of epithelial potassium transport: Special consideration of the nephron.
Fed. Proc. 40:2395-2397, 1981. 140. Costa Silva, V.L., Campiglia, S.S., deMello-Aires, M., Malnic, G. and Giebisch, G. Role of
luminal buffers in renal tubular acidification. J. Membrane Biol. 63:13-24, 1981. 141. Karlmark, B., Jaeger, P., Fein, H. and Giebisch, G. Coulometric acid-base titration in nanoliter
samples with glass and antimony electrodes. Am. J. Physiol. 242:F95-F99, 1982. 142. Chan, Y.L., Biagi, B. and Giebisch, G. Control mechanisms of bicarbonate transport across the
rat proximal convoluted tubule. Am. J. Physiol. 242:F532-F543, 1982. 143. O'Regan, M.G., Malnic, G. and Giebisch, G. Cell pH and luminal acidification in Necturus
proximal tubule. J. Membrane Biol. 69:99-106, 1982.
144. Oberleithner, H., Guggino, W. and Giebisch, G. Mechanism of distal tubular chloride transport in Amphiuma kidney. Am. J. Physiol. 242:F331-F339, 1982.
145. Wilcox, C., Cemerikic, D. and Giebisch, G. Differential effects of acute mineralo- and
glucocorticosteroid administration on renal acid elimination. Kidney Int. 21:546-556, 1982. 146. Guggino, W.B., Boulpaep, E.L. and Giebisch, G. Electrical properties of chloride transport
across the Necturus proximal tubule. J. Membrane Biol. 65:185-196, 1982. 147. Guggino, W.B., Windhager, E.E., Boulpaep, E.L. and Giebisch, G. Cellular and paracellular
resistances of the Necturus proximal tubule. J. Membrane Biol. 67:143-154, 1982. 148. Stanton, B. and Giebisch, G. Effect of pH on potassium transport by renal distal tubule. Am. J.
Physiol. 242:F544-F551, 1982. 149. Cemerikic, D., Wilcox, C.S. and Giebisch, G. Intracellular potential and K-activity in rat
�kidney proximal tubular cells in acidosis and K +” depletion. J. Membrane Biol. 69:159-165, 1982.
150. Stanton, B.A. and Giebisch, G. Potassium transport by renal distal tubule: Effect of potassium
loading. Am. J. Physiol. 243:F487-F493, 1982. 151. Giebisch, G. Renal tubular control of potassium transport. In: Membranes and Transport.
Volume 2, edited by Martonosi. New York: Plenum Publishing Corporation, 1982, p. 217-224. 152. Biemesderfer, D., Stanton, B., Kashgarian, M. and Giebisch, G. The ultrastructure of the distal
tubule of Amphiuma: A TEM and SEM study. In: 40th Ann. Proc. Electron Microscopy Soc. Amer., edited by Bailey, G.W. Washington, D.C., 1982, p. 170-171.
153. Oberleithner, H., Lang, F., Wang, W. and Giebisch, G. Effects of inhibition of chloride
transport in intracellular sodium activity on distal amphibian nephron. Pflugers Arch. 394:55-60, 1982.
154. Oberleithner, H., Giebisch, G. and Lang, F. Cellular mechanism of the furosemide-sensitive
transport system in the kidney. Klin. Wochenschr. 60:1173-1179, 1982. 155. Stanton, B.A. and Giebisch, G. Regulation of potassium homeostasis. In: Functional Regu-
lation at the Cellular and Molecular Levels, (edited by Corradino, P.A.) New York: Elsevier, 1982, p. 259-284.
156. Giebisch, G. Kaliummangelsyndrome durch Diuretika. In: Diuretika II, edited by Kruck, F.
and Schrey, A. Munich: Verlag Wolf und Sohn, 1982, p. 120-136. 157. Oberleithner, H., Guggino, W. and Giebisch, G. The effect of furosemide on luminal sodium,
chloride transport and potassium transport in the early distal tubule of Amphiuma kidney: Effects of potassium adaptation. Pflügers Arch. 396:27-33, 1983.
158. Kubota, T., Biagi, B.A. and Giebisch, G. Intracellular potassium activity measurements in
single proximal tubules of Necturus kidney. J. Membrane Biol. 73:51-60, 1983. 159. Kubota, T., Biagi, B.A. and Giebisch, G. Effect of acid-base disturbances on basolateral
membrane potential and intracellular potassium activity in the proximal tubule of Necturus. J. Membrane Biol. 73:61-68, 1983.
160. Guggino, W.B., London, R., Boulpaep, E.L. and Giebisch, G. Chloride transport across the
basolateral cell membrane of the Necturus proximal tubule: Dependence on bicarbonate and sodium. J. Membrane Biol. 71:227-240, 1983.
161. Koeppen, B. and Giebisch, G. Mineralocorticoid regulation of sodium and potassium transport
by the cortical collecting duct. In: Regulation and Development of Membrane Transport Processes, edited by Graves, S.J. New York: John Wiley & Sons, 1983, p. 89-104.
162. Oberleithner, H., Greger, R., Neuman, S., Lang, F., Giebisch, G. and Deetjen, P. Omission of
luminal potassium reduces cellular chloride in early distal tubule of amphibian kidney. Pflugers Arch. 398:18-22, 1983.
163. Oberleithner, H., Guggino, W. and Giebisch, G. Potassium transport in the early distal tubule
of Amphiuma kidney: Effects of potassium adaptation. Pflugers Arch. 396:185-191, 1983. 164. Koeppen, B.M., Biagi, B.A. and Giebisch, G. Intracellular microelectrode characterizaion of
the rabbit cortical collecting duct. Am. J. Physiol. 244:F35-F47, 1983. 165. Koeppen, B., Biagi, B.A. and Giebisch, G. Electrophysiology of mammalian renal tubule:
Inferences from intracellular microelectrode studies. Ann. Rev. Physiol. 45:497-517, 1983. 166. Karlmark, B., Jaeger, P. and Giebisch, G. Luminal buffer transport in rat cortical tubule:
relationship to potassium metabolism. Am. J. Physiol. 245:F584-F592, 1983. 167. Jaeger, P., Karlmark, B. and Giebisch, G. Ammonium transport in rat cortical tubule:
relationship to potassium metabolism. Am. J. Physiol. 245:F593-F600, 1983. 168. Jaeger, P., Bonjour, J.-P., Karlmark, B., Stanton, B., Kirk, R.G., Duplinsky, T. and Giebisch,
G. Influence of acute potassium loading on renal phosphate transport in the rat kidney. Am. J. Physiol. 245:F601-F605, 1983.
169. Chan, Y.L., Malnic, G. and Giebisch, G. Passive driving forces of proximal tubular fluid and
bicarbonate transport: gradient dependence of H+ secretion. Am. J. Physiol. 245:F622-F633, 1983.
170. London, R., Cohen, B., Guggino, W.B. and Giebisch, G. Regulation of intracellular chloride
activity during perfusion with hypertonic solutions in the Necturus proximal tubule. J. Membrane Biol. 75:253-258, 1983.
171. Cohen, B., Giebisch, G., Hansen, L.L., Teuscher, U. and Wiederholt, M. Relationship between
peritubular membrane potential and net fluid reabsorption in the distal renal tubule of Amphiuma. J. Physiol. 348:115-134, 1984.
172. Giebisch, G. A discussion of special transport functions in epithelia: Chairman's introduction.
In: Information and Energy Transduction in Biological Membranes, pgs. 389-390, l984. 173. Field, M., Stanton, B.A. and Giebisch, G. Influence of ADH on renal potassium handling: a
micropuncture and microperfusion study. Kidney Int. 25:502-511, 1984. 174. Green, R. and Giebisch, G. Luminal hypotonicity: a driving force for fluid absorption from the
proximal tubule. Am. J. Physiol. 246:F167-F174, 1984. 175. Guggino, W.B. and Giebisch, G. Mechanism of chloride transport across the basolateral cell
membrane of the nephron segment: The Necturus proximal tubule and the Amphiuma diluting segment. Fed. Proc. 43:2473-2487, 1984.
176. Hunter, M., Lopes, A.G., Boulpaep, E.L. and Giebisch, G. Single channel recordings of
calcium-activated potassium channels in the apical membrane of rabbit cortical collecting tubules. Proc. Natl. Acad. Sci. USA 81:4237- 4239, 1984.
177. Matsumura, Y., Cohen, B., Guggino, W.B. and Giebisch, G. Electrical effects of potassium
and bicarbonate on proximal tubule cells of Necturus. J. Membrane Biol. 79:145-152, 1984. 178. Matsumura, Y., Cohen, B., Guggino, W.B. and Giebisch, G. Regulation of the basolateral
potassium conductance of the Necturus proximal tubule. J. Membrane Biol. 79:153-161, 1984. 179. Wilcox, C.S., Granges, F., Kirk, G., Gordon, D. and Giebisch, G. Effects of saline infusion on
titratable acid generation and ammonia secretion. Am. J. Physiol. 247:F506-F519, 1984. 180. Cohen, B. and Giebisch, G. Relationship between potassium and conductance and transport in
renal tubular epithelium. In: Information and Energy Transduction in Biological Membranes, (edited by Helmreich, E.J.M. and Passow, H.) New York: Alan R. Liss, Inc., pgs. 391-401, l984.
181. Field, M.J. and Giebisch, G. Renal aspects of potassium homeostasis. In: Frontiers in
Physiological Research, edited by Garlick, D.G. and Korner, D.I. Australian Academy of Science, 1984, p. 180-192.
182. Field, M.J., Stanton, B.A. and Giebisch, G. Differential acute effects of aldosterone, dexa-
methasone, and hyperkalemia on distal tubular potassium secretion in the rat kidney. J. Clin. Invest. 74:1792-1802, 1984.
183. Field, M.J., Fowler, N. and Giebisch, G. Effects of enantiomers of indacrinone (MK-196) on cation transport by the loop of Henle and distal tubule studied by microperfusion in vivo. J. Pharmacol. Exptl. Therap. 230:62-68, 1984.
and Giebisch, G. Discovery and development of the (aminomethylaryloxy) acetic acid diuretics. In: Diuretics, (edited by Puschett, J.B.) Elsevier Science Publishing Co., Inc., 1984, p. 21-29.
185. Field, M.J., Fowler, N. and Giebisch, G. Tubular sites of action and relative potencies of the
enantiomers of indacrinone (MK-196). In: Diuretics, (edited by Puschett, J.B.) Elsevier Science Publishing Co., Inc., p. 352-354, l984.
186. Stanton, B., Giebisch, G., Klein-Robbenhaar, G., Wade, J. and DeFronzo, R.A. Effects of
adrenalectomy and chronic adrenal corticosteroid replacement on potassium transport in rat kidney. J. Clin. Invest. 75:1317-1326, 1985.
187. Wright, F.S. and Giebisch, G. Regulation of potassium excretion. In: The Kidney: Physiology
and Pathophysiology, edited by Seldin, D.W. and Giebisch, G. New York: Raven Press, 1985, p. 1223-1249.
188. Koeppen, B., Giebisch, G. and Malnic, G. Mechanism and regulation of renal tubular acidi-
fication. In: The Kidney: Physiology and Pathophysiology, edited by Seldin, D.W. and Gie-bisch, G. New York: Raven Press, 1985, p. 1491-1525.
189. Field, M.J. and Giebisch, G. Hormonal control of renal potassium excretion. Kidney Int.
27:379-387, 1985. 190. Stanton, B., Janzen, A., Klein-Robbenhaar, G., DeFronzo, R.A., Giebisch, G. and Wade, J.
Ultrastructure of rat initial collecting tubule: Effect of adrenal corticosteroid treatment. J. Clin. Invest. 75:1327-1334, 1985.
191. Koeppen, B. and Giebisch, G. Cellular electrophysiology of potassium transport in the
mammalian cortical collecting tubule. Pflügers Arch. 405:S143-S146, 1985. 192. Zalups, R., Stanton, B., Wade, J. and Giebisch, G. Structural adaptation of initial collecting
tubule following reduction in renal mass. Kidney Int. 27:636-642, 1985. 193. Chuckman, L., Parks, J.A., Bunnell, P.R., Plattner, J.J., Field, M.J. and Giebisch, G.H. Aryloxy
Acetic Esters. A new class of high-ceiling diuretics. Journal of Medicinal Chemistry 28:589-594, 1985.
194. Giebisch, G. The use of a diuretic agent as a probe to investigate site and mechanism of ion
transport processes. Arzneim.-Forsch./Drug. Res. 35:336-342, 1985.
195. Gullans, S.R., Avison, M.J., Ogino, T., Giebisch, G. and Shulman, R.G. NMR measurements of intracellular sodium in the rabbit proximal tubule. Am. J. Physiol. 249:F160-F168, 1985.
196. Guggino, W.B., Oberleithner, H. and Giebisch, G. Relationship between cell volume and ion
transport in the early distal tubule of the Amphiuma kidney. J. Gen. Physiol. 86:31-58, 1985. 197. Hropot, M., Fowler, N., Karlmark, B. and Giebisch, G. Tubular action of diuretics: Distal
effects on electrolyte transport and acidification. Kidney Int. 28:477-489, 1985. 198. Oberleithner, H., Guggino, W. and Giebisch, G. Resistance properties of the diluting segment
of the Amphiuma kidney: Influence of potassium adaptation. J. Membrane Biol. 88:139-147, 1985.
199. Giebisch, G. Mechanism of renal tubular acidification. Klin. Woch. 64:853-861, 1985. 200. Seldin, D. and Giebisch, G., Eds. The Kidney: Physiology and Pathophysiology, Vol. I, Raven
Press, New York, l985. 200a. Koeppen, B.M. and Giebisch, G.H. Mineralocorticoid regulation of sodium and potassium
transport by the rcortical collecting duct. In: Regulation & Development of Membrane Transport Processes, J.S. Graves, ed., Vol. 39, Society of Gen. Physiologists and John Wiley & Sons, New York, 1985, pp. 89-104.
201. Schild, L. Giebisch, G., Karniski, L. and Aronson, P.S. Chloride transport in the mammalian
proximal tubule. Pflügers Arch. 407:S156-S159, 1986. 202. Giebisch, G. and Aronson, P.S. The proximal nephron. In: Physiology of Membrane Disorders,
(edited by Andreoli, T.E., Hoffman, J.F., Fanestil, D.D. and Schultz, S.G.) New York: Plenum Publishing Corp., 1986, p. 669-700.
203. Giebisch, G. Physiology of Potassium Metabolism. In: Potassium in Cardiovascular and Renal
Medicine: Arrhythmias, Myocardial Infarction, and Hypertension, (edited by Whelton, P.K., Whelton, A. and Walker, W.G.) New York: Marcel Dekker, Inc., 1986, p. 3-22.
204. Rossetti, L., Klein-Robbenhaar, G., Giebisch, G., Smith, D., and Defronzo, R. Effect of Insulin
and Renal Potassium Metabolism. Am. J. Physiol. 2l: F60-F64, l987. 205. Hunter, M., Lopes, A.G., Boulpaep, E. and Giebisch, G. Regulation of single potassium
channels from apical membrane of rabbit collecting tubule. Am. J. Physiol. 251:F725-F733, 1986.
206. Capasso, G., Kinne, R., Malnic, G. and Giebisch, G. Renal bicarbonate reabsorption in the rat.
I. Effects of hypokalemia and carbonic anhydrase. J. Clin. Invest. 78:1558-1567, 1986.
207. Giebisch, G. Endocrine regulation of potassium transport. In: Endocrine Regulation of Potassium Transport, edited by Krück, F. and Thurau, K. Berlin, Heidelberg: Springer-Verlag, 1986, p. 89-103.
208. Thurau, K., Beck, F., Dorge, A., and Giebisch, G. Electron microbe analysis of different
rubidium uptake into cells of the distal nephron. l986. 209. Muto, S., Sansom, S., and Giebisch, G. Na-Dependent Effect of DOCA on cellular transport
properties of cortical collecting ducts from adrenalectomized rabbits. Am. J. Physiol., l986. 210. Lang, F., Oberleithner, H. and Giebisch, G. Electrophysiological heterogeneity of proximal
convoluted tubules in Amphiuma kidney. Am. J. Physiol. 251:F1063-F1072, 1986. 211. Better, O.S., Guckian, V., Giebisch, G., and Green, R. The Effect of Sodium Taruocholate on
Proximal Tubular Reabsorption in the Rat Kidney. Clinical Science, 72:l39-l4l, l987. 212. Giebisch, G. and Koeppen, B. Transport of sodium and potassium across the epithelium of the
distal nephron. In: Diuretics II: Chemistry, Pharmacology, and Clinical Applications, (edited by Puschett, J. B. and Greenberg, A.): Elsevier Science Publishing Co., Inc., 1987, p. 121-130.
213. Stanton, B., Pan, L., Deetjen, H., Guckian, V. and Giebisch, G. Independent effects of
aldosterone and potassium on induction of potassium adaptation in rat kidney. J. Clin. Invest. 79:198-206, 1987.
214. Schild, L., Giebisch, G., Karniski, L. and Aronson, P.S. Effect of formate on volume reab-
sorption in the rabbit proximal tubule. J. Clin. Invest. 79:32-38, 1987. 215. Hunter, M., Kawahara, K. and Giebisch, G. Potassium channels along the nephron. Federation
Proceedings 45:1223-1249, 1986. 216. Giebisch, G. Cell models of potassium transport in the renal tubule. In: Current Topics in
Membranes and Transport. Volume 28. Potassium Transport: Physiology and Pathology, (edited by Giebisch, G.) New York: Academic Press, 1987, p. 133-183.
�217. Stanton, B., Omerovic, A., Koeppen, B. and Giebisch, G. Electroneutral H +” secretion in
distal tubule of Amphiuma. Am. J. Physiol. 252:F691-F699, 1987. 218. Avison, M.J., Gullans, S.R., Ogino, T., Giebisch, G. and Shulman, R.G. Measurement of Na+
K+ coupling ratio of Na+ K+ ATPase in rabbit proximal tubules. Am. J. Physiol. 253:C126-C136, 1987.
219. Hunter, M. and Giebisch, G. Multi-barrelled K channels in renal tubules. Nature 327:522-524,
1987. 220. Better, O.S., Guckian, V., Giebisch, G. and Green, R. The effect of sodium taurocholate on
proximal tubular reabsorption in the rat kidney. Clinical Science 72:139-141, 1987.
221. Capasso, G., Jaeger, P., Giebisch, G., Guckian, V. and Malnic, G. Renal bicarbonate reab-
sorption in the rat. II. Distal tubule load dependence and effect of hypokalemia. J. Clin. Invest. 80:409-414, 1987.
222. Kawahara, K., Hunter, M. and Giebisch, G. Potassium channels in Necturus proximal tubule.
Am. J. Physiol. 253:F488-F494, 1987. 223. Giebisch, G., Guckian, V.A., Klein-Robbenhaar, G. and Klein-Robbenhaar, M.T. Renal
clearance and micropuncture studies of nisoldipine effects in spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 9:S24-S31, 1987.
224. Berliner, R.W. and Giebisch, G. Robert Franklin Pitts, 1908-1977. In: Biographical Memoirs,
Volume 57, Washington,D.C.: The National Academy Press, 1987, p. 323-344. 225. Maunsbach, A.B., Giebisch, G.H. and Stanton, B.A. Effects of flow rate on proximal tubule
ultrastructure. Am. J. Physiol. 253:F582-F587, 1987. 226. Muto, S., Giebisch, G., and Sansom, S. Effects of adrenalectomy on CCD: evidence for
differential response of two cell types. Am. J. Physiol. 253:F742-F752, 1987. 227. Sansom, S., Muto, S. and Giebisch, G. Na-dependent effects of DOCA on cellular transport
properties of CCDs from ADX rabbits. Am. J. Physiol. 253:F753-F759, 1987. 228. Horisberger, J.D., Hunter, M., Stanton, B. and Giebisch, G. The collecting tubule of
Amphiuma. I. Electrophysiological characterization. Am. J. Physiol. 253:F1263-F1272, 1987. 229. Horisberger, J.D., Hunter, M., Stanton, B. and Giebisch, G. The collecting tubule of
Amphiuma. II. Effects of potassium adaptation. Am. J. Physiol. 253:F1273-F1282, 1987. 230. Giebisch, G. Transport of electrolytes across renal tubules. In: Renal Physiology: People and
Ideas, (edited by Gottschalk, C.W., Berliner, R.W. and Giebisch, G.) Bethesda: American Physiological Society, 1987, p. 165- 216.
231. Hunter, M., Kawahara, K. and Giebisch, G. Calcium-activated epithelial potassium channels.
Mineral Electrolyte Metab. 14:48-57, 1988. 232. Muto, S., Sansom, S. and Giebisch, G. Effects of a high potassium diet on electrical properties
of cortical collecting ducts from adrenalectomized rabbits. J. Clin. Invest. 81:376-380, 1988. 233. Schild, L., Green, R. and Giebisch, G. Chloride transport in the proximal renal tubule. Ann.
Rev. Physiol. 50:97-110, 1988. 234. Beck, F.X., Dörge, A., Blumner, E., Giebisch, G. and Thurau, K. Cell rubidium uptake: A
method for studying functional heterogeneity in the nephron. Kidney Int. 33:642-651, 1988.
235. Horisberger, J.D. and Giebisch, G. Potassium-sparing diuretics. Renal Physiol. 10:198-220, 1987.
236. Muto, S., Giebisch, G. and Sansom, S. An acute increase of peritubular K stimulates K
transport through cell pathways of CCT. Am. J. Physiol. 255:F108-F114, 1988. 237. Hunter, M. and Giebisch, G. Calcium-activated K-channels of Amphiuma early distal tubule:
inhibition by ATP. Pflugers Arch. 412:331-333, 1988. 238. Guggino, W.B., Oberleithner, H. and Giebisch, G. The amphibian diluting segment. Am. J.
Physiol. 254:F615-F627, 1988. 239. Hunter, M., Oberleithner, H., Henderson, R.M. and Giebisch, G. Whole-cell potassium
currents in single early distal tubule cells. Am. J. Physiol. 255:F699-F703, 1988. 240. Ridderstrale, Y., Kashgarian, M., Koeppen, B., Giebisch, G., Stetson, D., Ardito, T. and
Stanton, B. Morphological heterogeneity of the rabbit collecting duct. Kidney Int. 34:655-670, 1988.
241. Velazquez, H. and Giebisch, G. Effect of diuretics on specific transport systems: Potassium.
Seminars in Nephrology 8:295-305, 1988. 242. Avison, M.J., Gullans, S.R., Ogino, T. and Giebisch, G. Na+ and K+ fluxes stimulated by Na+-
coupled glucose transport: evidence for a Ba2+- insensitive K+ efflux pathway in rabbit proximal tubules. J. Membrane Biol. 105:197-205, 1988.
243. Horisberger, J.-D. and Giebisch, G. Voltage dependence of the basolateral membrane
conductance in the Amphiuma collecting tubule. J. Membrane Biol. 105:257-263, 1988. 244. Horisberger, J.-D. and Giebisch, G. Intracellular Na+ and K+ activities and membrane
conductances in the collecting tubule of Amphiuma. J. Gen. Physiol. 92:643-655, 1988. 245. Gullans, S.R., Kone, B.C., Avison, M.J., and Giebisch, G. Succinate alters respiration,
membrane potential and intracellular K+ in proximal tubule. Am. J. Physiol. 255:F1170-F1177, 1988.
246. Beck, F.X., Dörge, A., Giebisch, G., Thurau, K. Renal excretion of rubidium and potassium:
An electron microprobe and clearance study. Kidney Int. 34:455-462, 1988. 247. Field, M.J., and Giebisch, G. Mechanisms of segmental potassium reabsorption and secretion.
In: The Regulation of Potassium Balance, edited by D.W. Seldin and G. Giebisch. Raven Press, Ltd., New York, 1989.
248. Giebisch, G., Schild, L., and Green, R. Mechanism of chloride transport across the mammalian
proximal tubule. Nephrology 1:179-189, 1988.
249. Sansom, S.C., Agulian, S., Muto, S., Illig, V., and Giebisch, G. K activity of CCD principal cells from normal and DOCA-treated rabbits. Am. J. Physiol. 256:F136-Fl42, l988.
250. Seldin, D. and Giebisch, G., Eds. The Regulation of Acid-Base Balance, Raven Press, New
York, l989. 251. Biemesderfer, D., Stanton, B., Wade, J.B., Kashgarian, M., Giebisch, G. Ultrastructure of
Amphiuma distal nephron: evidence for cellular heterogeneity. Am. J. Physiol. 256: C849-C857, 1989.
252. Malnic, G., Berliner, R.W., and Giebisch, G. Flow dependence of K+ secretion in cortical distal
tubules of the rat. Am. J. Physiol. 256: F932-F941, 1989. 253. Giebisch, G. Physiologie de la balance du potassium. Médecine et Hygiène 47:791-798, 1989. 254. Beck, F.-X., Dörge, A., Giebisch, G., and Thurau, K. Studies on the mechanism of rubidium-
induced kaliuresis. Kidney Int. 36:175-182, 1989. 255. Horisberger, J.-D., and Giebisch, G. Na-K Pump Current in the Amphiuma Collecting Tubule.
J. Gen. Physiol. 94:493-5l0, l989. 256. Chan, Y.L., Malnic, G., and Giebisch, G. Renal Bicarbonate Reabsorption in the Rat. III.
Distal Tubule Perfusion Study of Load Dependence and Bicarbonate Permeability. J. Clin. Invest. 84:93l-938, l989.
257. Geibel, J., Giebisch, G., and Boron, W.F. Effects of Acetate on Luminal Acidification
Processes in the S3 Segment of the Rabbit Proximal Tubule. Am. J. Physiol. 26:F586-F594, l989.
258. Geibel, J., Giebisch, G., and Boron, W.F. Basolateral sodium-coupled acid-base transport
mechanisms of the rabbit proximal tubule. Am. J. Physiol. 257:F790-F797, 1989. 259. Green, R., and Giebisch, G. Reflection coefficients and water permeability in rat proximal
tubule. Am. J. Physiol. 26:F658-F668, 1989. 260. Green, G., and Giebisch, G. Osmotic forces driving water reabsorption in the proximal tubule
of the rat kidney. Am. J. Physiol. 26:F669-F675, 1989. 260a. Sansom, S.C., and Giebisch, G. Potassium Homeostasis. In: Textbook of Nephrology, 2nd
ed. (S.G. Massry and R.J. Glassock, eds.) Williams and Wilkins, Baltimore, MD, 1989, pp. 257-266.
261. Field, M.J., and Giebisch, G. Physiologic Actions of Aldosterone on the Kidney. Hypertension:
Pathophysiology, Diagnosis, and Management. (edited by H. Laragh and B. H. Brenner) Raven Press, Chapter 79, 1273-1285, 1990.
262. Wang, W., Henderson, R.M., Geibel, J., White, S., and Giebisch, G. Mechanism of Aldos-terone-Induced Increase of K+ Conductance in Early Distal Renal Tubule Cells of the Frog. J. Mem. Biol. 111:277-289, 1989.
263. Wang, W., White, S., Geibel, J., and Giebisch, G. A Potassium Channel in the Thick
Ascending Limb of Henle's Loop of Rabbit Kidney. Am. J. Physiol. 258:F244-F253, 1990. 264. Schild, L., Aronson, P.S., and Giebisch, G. Effects of apical membrane chloride/formate
exchange on cell volume in the rabbit proximal convoluted tubule. Am. J. Physiol. 258:F530-F536, 1990.
265. Wade, J.B., Stanton, B.A., Field, M.J., Kashgarian, M., and Giebisch, G. Morphological and
Physiological Responses to Aldosterone: Time Course and Sodium Dependence. Am. J. Physiol. 259:F88-F94, 1990.
266. Wang, W., Schwab, A., and Giebisch, G. The regulation of the small conductance K+ channel
in the apical membrane of rat cortical collecting tubule. Am. J. Physiol. 259:F494-F502, 1990. 267. Giebisch, G., Hunter, M., Kawahara, K. Apical potassium channels in Amphiuma diluting
segment: effect of barium. J. Physiol. 420:313-323, 1990. 268. Malnic, G., Berliner, R.W., Giebisch, G. Distal Perfusion Studies: Transport Stimulation of
Native Tubule Fluid. Am. J. Physiol. 27:F1523-F1527, 1990. 269. Giebisch, G., Malnic, G., Berliner, R.W. Renal Transport and Control of Potassium Excretion.
In: The Kidney (edited by B. Brenner and F.C. Rector), 4th Edition, Saunders, 1990 Chapter 8, pgs. 283-317.
270. Giebisch, G. Distal Nephron Effects of Diuretics. In: Diuretics III: Chemistry, Pharmacology,
and Clinical Applications. Proc. 3rd Int. Conf. on Diuretics, Mexico, 1989 (edited by J.B. Puschett and A. Greenberg) pp. 667-677, Elsevier, New York, 1990.
271. Beck, F.X., Ring, T., Dörge, A., Giebisch, G. and Thurau, K. Effects of Diuretics on the
Cellular Handling of Potassium as Analyzed by Electron Microprobe Analysis. In: Diuretics III: Chemistry, Pharmacology, and Clinical Applications. Proc. 3rd Int. Conf. on Diuretics, Mexico, 1989 (edited by J.B. Puschett and A. Greenberg) pp. 678-684, Elsevier, New York, 1990.
272. Geibel, J., Zweifach, A., White, S., Wang, W., and Giebisch, G. K+ Channels of the
Mitochondrial injury: an early event in cisplatin toxicity to renal proximal tubules. Amer. J. Physiol. 258:F1181-F1187, 1990.
274. Beck, F.-X., Dörge, A., Giebisch, G., and Thurau, K. Effect of diuretics on cell potassium transport: An electron microprobe study. Kidney Int. 37:1423-1428, 1990.
275. Giebisch, G. Single Nephron Studies on the Action of Furosemide. In: Lasix - 25th
Anniversary Symposium, December 1989, pgs. 17-30, 1990. 276. Kawahara, K., Hunter, M., & Giebisch, G. Calcium-activated potassium channels in the
luminal membrane of Amphiuma diluting segment: voltage-dependent block by intracellular Na+ upon depolarisation. Pflügers Archiv 416:422-427, 1990.
277. Geibel, J., Giebisch, G. & Boron, W. F. Angiotensin II stimulates both Na+-H+ exchange and
Na+/HCO3- cotransport in the rabbit proximal tubule. Proc. Natl. Acad. Sci. 87:79l7-7920,
1990. 278. Malnic, G., Lopes, A.G., Cassola, A.C., Berardi, A.L., Mello Aires, M., & Giebisch, G. pH-
Stat Experiments in Proximal Renal Tubules. J. Mem. Biol. 118:121-130, 1990. 279. Kurtzman, N.A., Gonzalez, J., DeFronzo, R., & Giebisch, G. A Patient with Hyperkalemia
and Metabolic Acidosis. Amer. J. Kidney Dis. 15:333-356, 1990. 280. Berliner, R.W., & Giebisch, G. The Development of Renal Physiology since 1950. Am. J.
Kidney Dis. 16:530-535, 1990. 281. Beck, J.S., Breton, S., Mairbäurl, H., Laprade, R. and Giebisch, G. The Relationship Between
Sodium Transport and Intracellular ATP in the Isolated Perfused Rabbit Proximal Convoluted Tubule. Am. J. Physiol. 261:F634-F639, 1991.
282. Beck, J.S., Breton, S., Laprade, R. and Giebisch, G. Volume Regulation and Intracellular
Calcium in the Rabbit Proximal Convoluted Tubule. Am. J. Physiol. 29:F861-F867, 1991. 283. Wang, W. and Giebisch, G. Dual effect of ATP on the apical small conductance K+ channel
of the rat cortical collecting duct. J. Gen. Physiol. 98:35-61, 1991. 284. Schild, L., Aronson, P.S., and Giebisch, G. Basolateral transport pathways for K+ and Cl in
rabbit proximal tubule: effects on cell volume. Am. J. Physiol. 260:F101-F109, 1991. 285. Capasso, G., Unwin, R. and Giebisch, G. Role of the loop of Henle in urinary acidification.
Kidney Int. 40:S33-S35, 1991. 286. Capasso, G., Unwin, R., Agulian, S., and Giebisch, G. Bicarbonate transport along the loop of
Henle: I. Microperfusion studies of load and inhibitor sensitivity. J. Clin. Invest. 88:430-437, 1991.
287. Green, R., Giebisch, G., Unwin, R. and Weinstein, A.M. Coupled water transport by rat
proximal tubule. Am. J. Physiol. 261:F1046-F1054, 1991.
288. Capasso, G., Unwin, R., and Geibisch, G. Reabsorption of Bicarbonate Along the Nephron: Importance of Potassium. In: Nephrology (edited by M. Hatano), pp. 234-241, Springer-Verlag, Tokyo, 1991.
289. Wang, W. and Giebisch, G. The role of potassium and sodium channel in renal tubule
electrolyte transport. Japanese Journal of Nephrology, 33 (5):448-462, 1991. 290. Capasso, G., Unwin, R., Cianci, F., De Tommaso, G., De Santo, N.G., and Giebisch. G.
Regulation of bicarbonate transport along the distal nephron: effects of hormones, denervation and acid-base disturbances. Acid-Base Balance - Molecular, Cellular and Clinical Aspects. G. A. Borelli Conference Editorial Bios. pp. 125-134, 1991.
291. Giebisch, G. Renale Kontrolle der Kaliumhomöostase. Walter Siegenthaler und Rudolf Haas
Georg Thieme Verlag, Stuttgart, New York 3:20-25, 1991. 292. Welling, P., and Giebisch, G. Mineralocorticoid effects on the principal cell. Aldosterone:
Fundamental Aspects, J.P. Bonvalet, N.Farman, M. Lombes, M.E. Fatestin-Oblin, Eds. Colloque INSERM/John Libbey, Eurotext 215:305-135, 1991.
293. Zweifach, A., Desir, G.V., Aronson, P.S., and Giebisch, G. A Ca-activated K channel from
rabbit renal brush-border membrane vesicles in planar lipid bilayers. Am. J. Physiol. 261:F187-F196, 1991.
294. Wang, W. and Giebisch, G. Dual modulation of renal ATP- � �sensitive K + channel by
protein kinase A and C. Proc. Natl. Acad. Sci. 88:9722-9725, 1991. 295. Strieter, J., Weinstein, A.M., Giebisch, G.H. and Stephenson, J.L. Regulation of K Transport
in a Mathematical Model of the Cortical Collecting Tubule. Am. J. Physiol. 263:F1076-F1086, l992.
296. Strieter, J., Stephenson, J.L., Giebisch, G.H. and Weinstein, A.M. A Mathematical Model of
the Cortical Collecting Tubule of the Rabbit. Am. J. Physiol., 263:F1063-F1075, l992. 297. Wang, W., Cassola, A. and Giebisch, G. Arachidonic acid inhibits the K+ secretory channel of
cortical collecting duct of rat kidney. Am. J. Physiol. 31:F554-F559, 1992. 298. Beck, J.S., Breton, S., Giebisch, G., and Laprade, R. Potassium Conductance Regulation by
pH in Rabbit Proximal Convoluted Tubules. Am. J. Physiol. 263:F453-F458, 1992. 299. Wang, W., Sackin, H. and Giebisch, G. Renal potassium channels and their regulation. Ann.
Rev. Physiol. 54:81-90, 1992. 300. Lacchini, M.L.S., Lopes, A.G., Malnic, G. and Giebisch, G. Cisplatinum - Induced Lesion of
Proximal Tubule Acidification in the Rat. Renal Physiol. and Biochem. 15:106-112, 1992.
301. Okusa, M.D., Unwin, R.J., Velazquez, H., Giebisch, G., & Wright, F.S. Active Potassium Absorption by the Renal Distal Tubule. Am. J. Physiol., 31:F488-F493, 1992.
302. Beck, F.-X., Giebisch, G. and Thurau, K. Effect of K depletion on renal K and Rb excretion:
Evidence for activation of K reabsorption. Kidney International 42:272-278, 1992. 303. Stanton, B.A. and Giebisch, G. Renal potassium transport. In: Handbook of
Physiology:Renal Physiology, E. Windhager, ed., Oxford University Press, 813-874, 1992. 304. Wright, F. and Giebisch, G. Regulation of potassium excretion. In: The Kidney, 2nd Ed.,
Seldin and Giebisch, eds., Chapter 61, Raven Press, p. 2209, 1992. 305. Tsuchiya, K., Wang, W., Giebisch, G. and Welling, P.A. ATP is a coupling-modulator of
parallel Na/K ATPase-K channel activity in the renal proximal tubule. Proc. Natl. Acad. Sci. 89:6418-6422, 1992.
306. Wang, T., Giebisch, G. and Aronson, P.S. Effects of formate and oxalate on volume
absorption in rat proximal tubule. Am. J. Physiol. 263:F37-F42, 1992. 307. Zweifach, A., Desir, G.V., Aronson, P.S. and Giebisch, G. Inhibition of Ca-Activated K+
Channels from Renal Microvillus Membrane Vesicles by Amiloride Analogs. J. Membrane Biol. 128:115-122, 1992.
308. Breton, S., Beck, J.S., Cardinal, J., Giebisch, G. and Laprade, R. Involvement and source of
calcium in volume regulatory decrease of the proximal convoluted tubule. Am. J. Physiol. 263:F656-F664, 1992.
309. White, S., Boulpaep, E. and Giebisch, G. Differentiated transport properties of primary
cultured distal nephron. Cellular Physiol. and Biochem. 2:323-335, 1992. 310. Misler, S. and Giebisch, G. ATP-Sensitive Potassium Channels: Implications for
Pathophysiology and Pharmacology. Current Opinion in Nephrology and Hypertension 1:21-33, 1992.
311. Wang, T., Malnic, G., Giebisch, G. and Chan, Y.L. Renal Bicarbonate Absorption in the Rat:
4. Bicarbonate Transport Mechanisms in the Early and Late Distal Tubule. J. Clin. Invest. 91:2776-2784, 1993.
312. Giebisch, G., Klein-Robbenhaar, G., Klein-Robbenhaar, J., Ratheiser, K. and Unwin, R.
Renal and extrarenal sites of action of diuretics. Cardiovascular Drugs and Therapy 7:11-21, 1993.
313. Schwab, A., Geibel, J., Wang, W., Oberleithner, H. and Giebisch, G. Mechanism of activa-
tion of K channels by Minoxidil-sulfate in fused MDCK-cells. J. Membr. Biol. 132:125-136, l993.
314. Giebisch, G. Diuretic Action of Potassium Channel Blockers. Eur. J. Clin. Pharm.44 (Suppl. 1):S3-S5, 1993.
315. Giebisch, G., Wang, T. and Aronson, P.S. Chloride Transport Pathways in the Mammalian
Proximal Tubule. In: Isotonic Transport in Leaky Epithelia, Ussing, Fischbarg, Sten-Knudsen, Larsen, Willumsen and Thaysen, Eds., Alfred Benzon Symposium 34, Copenhagen, 1993, pp. 131-146.
316. Korbmacher, C., Boulpaep, E.L., Giebisch, G. and Geibel, J. Endothelin increases
intracellular calcium concentration in M-l mouse cortical collecting duct cells by a dual mechanism. Am. J. Physiol. 265:C349-C357, 1993.
317. Korbmacher, C., Segal, A.S., Fejes-Toth, G., Giebisch, G. and Boulpaep, E.L. Whole-cell
currents in single and confluent M-1 mouse cortical collecting duct cells. J. Gen. Physiol. 102:761-793, 1993.
318. Wang, T., Agulian, S.K., Giebisch, G. and Aronson, P.S. Effects of Formate and Oxalate on
Chloride Absorption in the Rat Distal Tubule. Am. J. Physiol. 264:F730-F736, 1993. 319. Welling, P.A., Caplan, M. and Giebisch, G. Aldosterone-mediated Na/K ATPase expression
is 1 isoform specific in the renal cortical collecting duct. J. Biol Chem. 268:23469-23476, 1993.
320. Brady, H.R., Zeidel, M.L., Kone, B.C., Giebisch, G., and Gullans, S.R. Differential actions of
cisplatin in proximal tubule and inner medullary collecting duct cells. J. Pharm. Exptl. Thera. 265:1421-1428, 1993.
321. Wang, W., Geibel, J. and Giebisch, G. Mechanism of apical K+-channel modulation in principal renal tubule cells: Effect of inhibition of basolateral Na+-K+-ATPase. J. Gen. Physiol. 101:673-694, 1993.
322. Cassola, A.C., Giebisch, G. and Wang, W. Vasopressin increases the density of apical low-
conductance K+ channels in rat CCD. Am. J. Physiol. 264:F502-F509, 1993. 323. Giebisch, G. and Wang, W. Properties of renal potassium channels and their regulation. In:
Diuretics IV: Chemistry, Pharmacology and Clinical Applications. J.B. Puschett and A. Greenberg, eds. Elsevier Science Publishers, pp. 79l-800, l993.
324. Giebisch, G. and Klein-Robbenhaar, G. Recent Studies on the Characterization of Loop
Diuretics. J. Cardiovasc. Pharmacol. 22 (Suppl. 3):S1-S10, 1993. 325. Oberleithner, H., Giebisch, G., and Geibel, J. Imaging the lamellipodium of migrating
epithelial cells in vivo by atomic force microscopy. Pflügers Arch. 425:506-510, 1993. 325a. Clinical Disturbances of Water Metabolism. D.W. Seldin and G. Giebisch, eds. Raven
Press, New York, 1993.
326. Giebisch, G. Acceptance of the 1993 A. N. Richards Award. Kidney Int. 45 (Suppl.
44):S110-S111, 1994. 327. Hropot, M., Klaus, E., Unwin, R. and Giebisch, G. Diminished Diuretic and Natriuretic
Response to Furosemide in Potassium-Depleted Rats. Renal Physiol. Biochem. 17:10-20, 1994.
328. Oberleithner, H., Schwab., A., Wang, W., Giebisch, G., Hume, F. and Geibel, J. Living Renal
Epithelial Cells Imaged by Atomic Force Microscopy. Nephron 66:8-13, 1994. 329. Capasso, G., Unwin, R., Ciani, F., De Santo, N.G., De Tommaso, G., Russo, F. and Geibisch,
G. Bicarbonate Transport Along the Loop of Henle: II. Effects of Acid-Base, Dietary and Neurohumoral Determinants. J. Clin. Invest. 94:30, 1994.
330. Wang, W., McNicholas, C.M., Segal, A.S., and Giebisch, G. A novel approach allows
identification of K channels in the lateral membrane of rat CCD. Am. J. Physiol. 266:F813-F822, 1994.
331. Capasso, G., Malnic, G., Wang, T. and Giebisch, G. Acidification in mammalian cortical
distal tubule. Kidney Int. 45:1543-1554, 1994. 332. Sansom, S.C. and Giebisch, G.H. Control of Potassium Excretion. In: Textbook of Ne-
phrology, Third Edition, Massry & Glassock, Eds., Williams & Wilkins, Baltimore, Ch. 19.1, pp. 293-304, 1994.
333. Field, M.J., Berliner, R.W. and Giebisch, G. Regulation of renal potassium metabolism. In:
Textbook of Nephrology: Clinical Disorders of Fluid and Electrolyte Metabolism. R. Narins, Ed. 5th Ed., McGraw Hill, pp. 147-174, 1994.
334. Unwin, R., Capasso, G. and Giebisch, G. Potassium and sodium transport along the loop of
Henle: Effects of altered dietary potassium intake. Kidney Int. 46:1092-1099, 1994. 335. Wang, W-H., Cassola, A. and Giebisch, G. Involvement of actin cytoskeleton in modulation
of apical K channel activity in rat collecting duct. Am. J. Physiol. 167:F592-F598, 1994. 336. McNicholas, C.M., Wang, W., Ho, K., Hebert, S.C. and Giebisch, G. Regulation of ROMK1
337. Wang, T., Segal, A.S., Giebisch, G. and Aronson, P.S. Stimulation of Chloride Transport by
cAMP in the Rat Proximal Tubule. Am. J. Physiol. 268:F204-F210, 1995. 338. Kubokawa, M., Wang, W., McNicholas, C.M. and Giebisch, G. Role of Ca2+/calmodulin-
dependent protein kinase II in Ca2+-induced K+ channel inhibition in rat CCD principal cell. Am. J. Physiol. 268:F211-F219, 1995.
339. Unwin, R., Capasso, G. and Giebisch, G. Bicarbonate transport along the loop of Henle:
effects of adrenal steroids. Am. J. Physiol. 268:F234-F239, 1995. 340. Giebisch, G. Renal potassium channels: An overview. Kidney Int. 48:1004-1009, 1995. 341. Wang, T., Wang, W-H., Klein-Robbenhaar, J. and Giebisch, G. Effects of glyburide on renal
tubule transport and K channel activity. J. Renal Physiol. and Biochem. 18:169-182, 1995. 342. Wang, T., Wang, W-H., Klein-Robbenhaar, G. and Giebisch, G. Effects of a novel K ATP
channel blocker on renal tubule function and K channel activity. J. Exper. Pharmacol. and Therap. 273:1382-1389, 1995.
343. Kubokawa, M., McNicholas, C.M., Higgins, M.A., Wang, W-H. and Giebisch, G. Regulation
of renal ATP-sensitive K+ channel by membrane-bound protein phosphatases in rat principal tubule cell. Am. J. Physiol. 269:F355-F362, 1995.
344. Ohno, A., Beck, F-X., Pfaller, W., Giebisch, G. and Wang, T. The effects of chronic
hyperfiltration on proximal tubule bicarbonate transport and cell electrolytes. Kidney Int. 48:712-721, 1995.
345. Oberleithner, H., Brinckmann, E., Giebisch, G. and Geibel, J. Visualizing life on biomem-
branes by atomic force microscopy. Kidney Int. 48:923-929, 1995. 346. Unwin, R.J., Capasso, G., Giebisch, G., Shirley, D.G. and Walter, S.J. Loop of Henle (LOH)
potassium transport and the urinary concentrating mechanism. In Acid Base and Electrolyte Balance, Vol. II. N.G. DeSanto and G. Capasso, eds., Inst. Ital. Per gli Studi Filosofici, 1996.
347. McNicholas, C.M., Yang, Y. Giebisch, G. and Hebert, S.C. Molecular Site for Nucleotide
Binding on an ATP-sensitive Renal K+ channel (ROMK2). Am. J. Physiol. 40:F275-F285, 1996.
348. Giebisch, G. and Wang, W. Potassium Transport: From Clearance to Channels and Pumps.
Kidney Int. 49:1624-1631, 1996. 349. Wang, T., Egbert, A.L. Jr., Abbiati, T., Aronson, P.S. and Giebisch, G. Mechanisms of
Stimulation of Proximal Tubule Chloride Transport by Formate and Oxalate. Am. J. Physiol. 40:F446-F450, 1996.
350. Tsuchiya, K., Giebisch, G. and Welling, P.A. Aldosterone-dependent regulation of Na-K-
ATPase subunit mRNA in the rat CCD: competitive PCR analysis. Am. J. Physiol. 271: F7-F15, 1996.
351. McNicholas, C.M., Guggino, W.B., Schwiebert, E.M., Hebert, S.C., Giebisch, G. and Egan,
M.E. Sensitivity of a Cloned Renal K+ Channel (ROMK2) to the Inhibitory Sulfonylurea
Compound, Glibenclamide, is Enhanced by Co-expression with the ATP-binding Cassette Transporter CFTR. Proc. Natl. Acad. Sci. 93:8083-8088, 1996.
352. Wang, T. and Giebisch, G. Effects of Angiotensin II on Electrolyte Transport in the Early and
Late Distal Tubule in Rat Kidney. Am. J. Physiol. 271:F143-F149, 1996. 353. Giebisch, G. The Role of Potassium Channels in Renal Function. In: Proceedings of the
Symposium in Honor of John Young's 60th Birthday, A. Dinudom and P. Komwatana, eds., Univ. of Sydney Printing Service, NSW, Australia, 1996, pp 115-121.
354. Aleo, M.D., Wang, T., Giebisch, G., Sanders, M.J., Walsh, A.H. and Lopez-Anaya, A. Model
Development and Analysis of Tenidap-Induced Proteinuria in the Rat. J. Pharm. and Exper. Therap. 279:1318-1326, 1996.
355. Giebisch, G. The Control of Potassium Homeostasis by Pumps and Channels: New Insights
and Molecular Mechanisms. Publikationen der Jung-Stiftung für Wissenschaft und Forschung, pp. 159-164, 1996.
356. Giebisch, G., Malnic, G. and Berliner, R.W. Control of renal potassium excretion. In The
Kidney, 5th ed., B.M. Brenner and F.C. Rector, eds. W.B. Saunders, Philadelphia, PA, 1996, pp. 371-407.
357. Wang, W., Hebert, S.C., and Giebisch, G. Renal K Channels: Structure and Function. Ann.
Rev. Physiol. 59:413-416, 1997. 358. Lu, M., Giebisch, G. and Wang, W. Nitric oxide-induced hyperpolarization stimulates low-
conductance Na+ channel of rat CCD. Am. J. Physiol. 272:F498-F504, 1997. 359. Wu, M-S., Biemesderfer, D., Giebisch, G. and Aronson, P.S. Role of NHE3 in Mediating
Renal Brush Border Na+-H+ Exchange: Adaptation to Metabolic Acidosis. J. Biol. Chem. 271:32749-32752, 1997.
360. Alpern, R., Giebisch, G. and Seldin, D. Renal Electrolyte Transport and its Regulation. In
Clinical Diuretics and Pharmacology, D. Seldin and G. Giebisch, eds., Academic Press, San Diego, pp. 31-74, 1997.
361. Giebisch, G. Recent Advances in the Field of Renal Potassium Excretion: What Can we
Learn from Potassium Channels? Yale J. Biol. and Med. 70:311-322, 1997. 362. Merot, J., Giebisch, G. and Geibel, J. Intracellular acidification induces Cl/HCO3 exchange
activity in the basolateral membrane of ß-intercalated cells of the rabbit cortical collecting duct. J. Memb. Biol. 159:253-262, 1997.
Giebisch, G. and Egan, M.E. A Functional CFTR-NBF1 is Required for ROMK2-CFTR Interaction. Am. J. Physiol. 273:F843-F848, 1997.
364. Wang, T., Egbert, A.L. Jr., Aronson, P.S., and Giebisch, G. Effect of Metabolic Acidosis on
NaCl Transport in the Proximal Tubule. Am. J. Physiol. 274:F1015-F1019, 1998. 365. Lu, M., Giebisch, G. and Wang, W-H. Nitric oxide links the apical Na+ transport to the
basolateral K+ conductance in the rat CCD. J. Gen. Physiol. 110:717-726, 1997. 366. Aronson, P.S. and Giebisch, G. Mechanisms of chloride transport in the proximal tubule.
Am. J. Physiol. 273:F179-F192, 1997. 367. McNicholas, C.M., MacGregor, G.G., Islas, L.D., Yang, Y., Hebert, S.C. and Giebisch, G.
pH-dependent modulation of the cloned renal K+ channel, ROMK. Am. J. Physiol. 275:F972-F981, 1998.
368. Muto, S., Asano, Y., Seldin, D. and Giebisch, G. Basolateral Na+ pump modulates apical Na+
and K+ conductances in rabbit cortical collecting ducts. Am. J. Physiol. 276:F143-F158, 1999. 369. MacGregor, G.G., Xu, J.Z., McNicholas, C.M., Giebisch, G. and Hebert, S.C. Partially active
channels produced by PKA site mutation of the cloned renal K+ channel, ROMK2 (Kir1.2). Am. J. Physiol. 275: F415-F422, 1998.
370. Wang, T., Courtois-Coutry, N., Giebisch, G. and Caplan, M.J. A Tyrosine-Based Signal
Regulates H/K-ATPase Mediated Potassium Resorption in the Kidney. Am. J. Physiol. 275:F818-F826, 1998.
371. Unwin, R.J., Capasso, G., Giebisch, G., Shirley, D.G. and Walter, S.J. Loop of Henle (LOH)
Potassium Transport and the Urinary Concentrating Mechanism. In Acid-Base and Electrolyte Balance, DeSanto and Capasso, eds., Inst. Ital. Per gli Studi Filosofici, 1995 (Proc. 2nd Borelli Cong., July 1995) pp 243-256.
372. Shirley, D.G., Walter, S.J., Unwin, R.J. and Giebisch, G. Contribution of Na+/H+ exchange to
sodium reabsorption in the thick ascending limb of Henle: A microperfusion study in rats. J. Physiol. 513:243-249, 1998.
373. Giebisch, G. Renal potassium transport: Mechanisms and regulation. Am. J. Physiol.
274:F817-833, 1998. 374. Schultheis, P.J., Clarke, L.L., Meneton, P., Miller, M.L., Soleimani, M., Harline, M., Riddle,
T., Duffy, J., Doetschman, T., Wang, T., Giebisch, G., Aronson, P., Lorenz, J. and Shull, G.E. Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nature Genetics 19 (3): 282-285, 1998.
375. Giebisch, G. Commentary on Renal Tubular Secretion of Potassium in the Normal Dog by R.
W. Berliner and T. J. Kennedy, Jr., J. Am. Soc. Neph. 9:1341-1345, 1998.
376. Pfaller, W., Seppi, T., Ohno, A., Giebisch, G. and Beck, F.X. Quantitative morphology of renal cortical structures during compensatory hypertrophy. Exp. Nephrol. 6: 308-319, 1998.
377. Wagner, C.A., Giebisch, G., Lang, F. and Geibel, J.P. Angiotensin II stimulates vesicular H+-
ATPase in rat proximal tubular cells. Proc. Natl. Acad. Sci. USA 95:9665-9668, 1998. 378. Wang, T. and Giebisch, G. Tubule function in transgenic mice. Exp. Nephrol. 6: 447-453,
1998. 379. Bailey, M., Capasso, G., Agulian, S., Giebisch, G. and Unwin, R. The relationship between
distal tubular proton secretion and dietary potassium depletion: evidence for upregulation of H+-ATPase. Nephrology, Dialysis and Transplantation 14:1435-1440, 1999.
380. Giebisch, G. and Berliner, R.W. Origins of Renal Physiology in the USA. Am. J. Nephrol.
19:266-273, 1999. 381. Wang, T., Yang, C-L., Abbiati, T., Schultheis, P.J., Shull, G.E., Giebisch, G. and Aronson,
P.S. Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. Am. J. Physiol. 277:F298-F302, 1999.
382. Giebisch, G., Malnic, G., and Berliner, R.W. Control of Renal Potassium Excretion. In The
Kidney, 6th edition, Barry M. Brenner, ed., W. B. Saunders, pp. 417-454, 1999. 383. Muto, S., Asano, Y., Seldin, D. and Giebisch, G. Basolateral Na+ pump modulates apical Na+
and K+ conductances in rabbit cortical collecting ducts. Am. J. Physiol. 276: F143-F158, 1999.
384. Giebisch, G. Physiological Roles of Renal Potassium Channels. Seminars in Nephrol.19:458-
471, 1999. 385. Grishin, A.V., Reinhard, J., Dunbar, L.A., Courtois-Coutry, N., Wang, T., Giebisch, G. and
Caplan, M.J. Nongastric H+, K+-ATPase: Cell Biologic and Functional Properties. Sem. in Nephrol. 19: 421-430, 1999.
386. Unwin, R.J., Walter, S.J., Giebisch, G., Capasso, G. and Shirley, D.G. Localisation of diuretic
effects along the loop of Henle in vivo. Clinical Sci. 98:481-488, 2000. 387. Leipziger, J., Cooper, G.J., Xu, J., Hebert, S.C. and Giebisch, G. PKA site mutations of
ROMK2 channels shift the pH-dependence to more alkaline values. Am. J. Physiol. 279: F919-F926, 2000.
388. Wang, W., Lerea, K.M., Chan, M. and Giebisch, G. Protein tyrosine kinase regulates the
number of renal secretory K channels. Am. J. Physiol., 278: F165-F171, 2000. 389. Giebisch, G., Wang, W. and Hebert, S. ATP-dependent potassium channels in the kidney. In:
Handbook of Experimental Pharmacology, Pharmacology of Ionic Channel Function. M.
Endo, M. Mishina, and Y. Kurachi, Eds., Springer-Verlag, Germany, Chapter 10, 2000, pp 243-264.
390. Malnic, G., Muto, S. and Giebisch, G. Regulation of Potassium Excretion. In The Kidney:
Physiology and Pathophysiology, 3rd edition, D. Seldin and G. Giebisch, eds., Lippincott-Raven Press, Chapter 58, 2000, pp 1575-1613.
391. Giebisch, G. Canaux potassiques et rein. Néphrologie 21:223-228, 2000. 392. Lu, Ming, MacGregor, Gordon G., Wang, Wenhui, and Giebisch, Gerhard. Extracellular
ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney. J. Gen. Physiol. 116: 299-310, 2000.
393. Giebisch, G. Author commentary. In Milestones in Nephrology: Micropuncture study of
renal potassium excretion in the rat. J. Am. Soc. Nephrol. 11: 1354-1369, 2000. 394. Giebisch, G. and Wang, W. Renal tubule potassium channels: Function, regulation and
structure. Acta Physiol. Scand. 170: 153-173, 2000. 395. Sansom, S.C., Muto, S. and Giebisch, G. Control of Potassium Excretion. In The Textbook
of Nephrology, 4th edition, Lippincott, Williams and Wilkins, Philadelphia, PA 2001, pp 276-288.
S.C., Giebisch, G. and Wang, W-H. Regulation of ROMK1 channels by protein tyrosine kinase and tyrosine phosphatase. J. Biol. Chem.276:7156-7163, 2001.
397. Knauf, F., Thomson, R.B., Yang, C-L., Mentone, S.A., Giebisch, G. and Aronson, P.
Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc. Natl. Acad. Sci. 98:9425-9430, 2001.
398. Eickelberg, O., Geibel, J., Seebach, F., Giebisch, G. and Kashgarian, M. Potassium-induced
HSP-72 expression is mediated via rapid calcium influx in renal epithelial cells. Am. J. Physiol. 281: F280-F287, 2001.
399. Dong, K., Xu, J., Vanoye, C.G., Welch, R., MacGregor, G., Giebisch, G.H. and Hebert, S.C.
An amino acid triplet in the NH2 terminus of rat ROMK1 determines interaction with SUR2B. J. Biol. Chem. 47:44347-44353, 2001.
400. Giebisch, G. Renal potassium channels: Function, regulation, and structure. Kidney Int. 60:
436-445, 2001. 401. Wang, T., Yang, C-L., Abbiati, T., Shull, G.E., Giebisch, G. and Aronson, P.S. Essential role
of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule. Am. J. Physiol. 281(2):F288-F292, 2001.
402. Wang, T., Hropot, M., Aronson, P.S. and Giebisch, G. Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron. Am. J. Physiol. 281:F1117-F1122, 2001.
403. MacGregor, G.G., Dong, K., Vanoye, C.G., Tang, L., Giebisch, G. and Hebert, S.C.
Nucleotides and phospholipids compete for binding to the C-terminus of KATP channels. Proc. Natl. Acad. Sci. USA 99:2726-2731, 2002.
404. Lin, D-H., Sterling, H., Lerea, K.M., Welling, P., Jin, L., Giebisch, G. and Wang, W-H. K
depletion increases the protein tyrosine kinase-mediated phosphorylation of ROMK. Am. J. Physiol.283:F671-F677, 2002.
405. Berliner, R.W. and Giebisch, G. Remembrances of renal potassium transport. J. Memb. Biol.
184:225-232, 2002. 406. Vanoye, C.G., MacGregor, G.G., Dong, K., Tang, L., Hall, A.E., Lu, M., Giebisch, G. and
Hebert, S.C. The carboxyl-termini of KATP channels bind nucleotides. J. Biol. Chem. 277:23260-23270, 2002.
407. Giebisch, G. The scientific achievements of R. F. Pitts and V. du Vigneaud. Am. J. Nephrol
22: 186-191, 2002. 408. Capasso, G., Unwin, R., Rizzo, M., Pica, A. and Giebisch, G. Bicarbonate transport along the
loop of Henle: Molecular mechanisms and regulation. J. Nephrol. 15: S88-S96, 2002. 409. Wagner, C.A., Finberg, K.E., Stehberger, P.A., Lifton, R.P., Giebisch, G.H., Aronson, P.S.
and Geibel, J.P. Regulation of the expression of the Cl- /anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int. 62:2109-2117, 2002.
410. Giebisch, G. A trail of research on potassium. Kidney Int. 62: 1498-1512, 2002. 411. Karniski, L.P., Wang, T., Everett, L.A., Green, E.D., Giebisch, G. and Aronson, P.A.
Formate-stimulated NaCl absorption in the proximal tubule is independent of the pendrin protein. Am. J. Physiol. 283: F952-F956, 2002.
412. Wang, T., Giebisch, G. and Aronson, P.S. Use of transgenic animals to study renal acid-base
transport. J. Nephrol. 15: S151-S160, 2002. 413. Lu, M., Wang, T., Yan, Q., Yang, X., Dong, K., Knepper, M.A., Wang, W-H., Giebisch, G.,
Shull, G.E. and Hebert, S.C. Absence of small-conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter’s) knockout mice. J. Biol. Chem. 277:37881-37887, 2002.
414. Lu, M., Hebert, S.C. and Giebisch, G. Hydrolyzable ATP and PIP2 modulate the small-
conductance K+ channel in apical membranes of rat cortical collecting duct. J. Gen. Physiol. 120: 603-615, 2002.
415. Beck, F.-X., Neuhofer, W., Dörge, Shull, G.E., Giebisch, G. and Wang, T. Intracellular Na concentration and Rb uptake in proximal convoluted tubule (PCT) cells and abundance of Na/K-ATPase α1-subunit in NHE3-/- mice. Pflüger’s Arch. 446:100-105, 2003.
416. Amorim, J.B.O., Bailey, M.A., Musa-Aziz, R., Giebisch, G. and Malnic, G. Role of luminal
anion and pH in distal tubule potassium secretion. Am. J. Physiol. 53:F381-F388, 2003. 417. Giebisch, G., Hebert, S.C. and Wang, W. New aspects of renal potassium transport. Pflugers
Arch. 446: 289-297, 2003. 418. Wang, T., Sterling, H., Shao, W.A., Yan, QS, Bailey, M.A., Giebisch, G. and Wang, W.H.
Inhibition of heme oxygenase decreases sodium and fluid absorption in the loop of Henle. Am. J. Physiol. 285:F484-F485, 2003.
419. Wagner, C.A., Lükewille, U., Valles, P., Breton, S., Brown, D., Giebisch, G.H. and Geibel,
J.P. A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse. Pflugers Arch. 446: 623-632, 2003.
420. Muto, S., Asano, Y., Wang, WH., Seldin, D. and Giebisch, G. Activity of the basolateral K+
channels is coupled to the Na-K-ATPase in the cortical collecting duct. Am. J. Physiol. 285:F945-F954, 2003.
J.P. and Wagner, C.A. Localization and regulation of the ATP6V0A4 (a4) vacuolar H+-ATPase subunit defective in an inherited form of distal renal tubular acidosis. J. Am. Soc. Nephrol. 14: 3027-3038, 2003.
MacGregor, G.G., Giebisch, G., Hebert, S.C. and Lifton, R.P. WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. Nature Genetics 35(4): 372-376, 2003.
423. Beck, F.-X., Neuhofer, W., Dörge, A., Giebisch, G. and Wang, T. Intracellular Na
concentration and Rb uptake in proximal convoluted tubule cells and abundance of Na/K-ATPase α1-subunit in NHE3-/- mice. Pflüger’s Arch. 446: 100-105, 2003.
424. Bailey, M.A., Giebisch, G., Abbiati, T., Aronson, P.S. and Wang, T. NHE2-mediated
bicarbonate reabsorption in the distal tubule of NHE3 null mice. J. Physiol. 561.3, 765-775, 2004.
425. Malnic, G., Bailey, M.A. and Giebisch, G. Control of Renal Potassium Transport. In: The
Kidney, 7th ed., B. Brenner and F.C. Rector, eds., W.B. Saunders, London, Chapter 10, pp 453-496, 2004.
426. Giebisch, G. Homer Smith’s Contribution to Renal Physiology. J. Nephrology 17: 159-65,
2004.
427. Lu, M., Wang, T., Yan, Q., Wang, W., Giebisch, G. and Hebert, S.C. ROMK is required for expression of the 70ps channel in the thick ascending limb. Am. J. Physiol. 286:F490-F495, 2004.
428. Lin, D.H., Sterling, H., Yang, B., Hebert, S.C., Giebisch, G. and Wang, W-H. Protein
tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct. Am. J. Physiol. 286: F881-F892, 2004.
of vacuolar H+ ATPases in intercalated renal tubule cells by aldosterone. Proc. Nat’l. Acad. Sci. 101: 2636-2641, 2004.
430. Giebisch, G. Two classical papers in acid-base physiology – Contributions of R.F. Pitts, R.S.
Alexander and W. D. Lotspeich. Am. J. Physiol. 287; F864-F865, 2004. 431. Hebert, S.C. and Giebisch, G. Roderick MacKinnon, M.D. honored by 2003 prize in
chemistry for his work on elucidating the structure of ion channels. J. Am. Soc. Nephrol. 15: 1096-1097, 2004.
432. Hebert, S.C., Desir, G., Giebisch, G., and Wang, W.H. Molecular diversity and regulation of
renal potassium channels. Physiological Reviews 85: 319-371, 2005. 433. Giebisch, G. Challenges to potassium metabolism: Internal distribution and external balance.
Wiener Klinische Wochenschrift 116/11-12: 353-366, 2004. 434. Giebisch, G. Heini Murer: Congratulations on his 60th birthday. Pflüger’s Arch. 448: 557-
560, 2004. 435. Kahle, K. T., MacGregor, G. G., Wilson, F. H., Van Hoek, A.N., Brown, D., Ardito, T.,
Kashgarian, M., Giebisch, G., Hebert, S. C., Boulpaep. E.L. and Lifton, R.P. Paracellular Cl- permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension. Proc. Natl. Acad. Sci. 101: 14877-14882, 2004.
436. Lin, D-H., Sterling, H., Wang, Z., Babilonia, E., Yang, B., Dong, K., Hebert, S.C.,
Giebisch, G. And Wang, W-H. ROMK1 channel activity is regulated by monoubiquitination. Proc. Natl. Acad. Sci. USA 102:4306-4311, 2005.
437. O’Connell, A.D., Leng, Q., Dong, K., MacGregor, G.G., Giebisch, G. and Hebert, S.C.
Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK). Proc. Natl. Acad. Sci. 102:9954-9959, 2005.
G., Geibel, J.P. and Lifton, R.P. The B1-subunit of the H+ ATPase is required for maximal urinary acidification. Proc. Natl. Acad. Sci. USA 102: 13616-13621, 2005.
439. Bailey, M.A., Cantone, A., Yan, Q., MacGregor, G.G., Leng, Q., Amorim, J.B.O., Wang, T., Hebert, S.C., Giebisch, G. and Malnic, G. Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter’s syndrome and in adaptation to a high-K diet. Kidney Int 70:51-59, 2006.
440. Li, D., Wang, Z., Sun, P., Jin, Y., Lin, D-H., Hebert, S.C., Giebisch, G. and Wang, W-H.
Inhibition of mitogen-activated protein kinase stimulates the Ca2+-dependent big conductance K channels (BK) in the cortical collecting duct. Proc. Natl. Acad. Sci. USA 103:19569-19574, 2006.
441. Leng, Q., MacGregor, G.G , Dong, K., Giebisch, G., and Hebert, S.C. Subunit-subunit
interactions are critical for proton sensitivity of ROMK: Evidence in support of an intermolecular gating mechanism. Proc. Natl. Acad. Sci, USA 103: 1982-1987, 2006.
442. Lu, M., Leng, Q., Egan, M.E., Caplan, M.J., Boulpaep, E.L., Giebisch, G.H. and Hebert, S.C.
CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney. J. Clin. Invest. 116: 797-807, 2006.
C.M., Lifton, R.P. and Hebert, S.C. WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalemia, regulates the K+ channel ROMK1 (Kir1.1). J. Physiol. 571: 275-286, 2006.
Giebisch, G., Han, Z-G., and Wang, W-H. Inhibitor of growth 4 (ING4) is up-regulated by a low K intake and suppresses renal outer medullary K channels (ROMK) by MAPK stimulation. Proc. Natl. Acad. Sci. 104: 9517-9522, 2007.
445. Hebert, S.C. and Giebisch, G. Response to “Reemergence of the maxi K+ as a K+ secretory
channel.” Kidney Int. 71:1322-1325, 2007. 446. Giebisch, G., Krapf, R. and Wagner, C. Renal and extrarenal regulation of potassium.
Kidney Int. 72: 397-410, 2007. 447. Malnic, G., Muto, S. and Giebisch, G. Regulation of Potassium Excretion. In The Kidney:
Physiology and Pathophysiology, 4th edition. R. Alpern and S. Hebert, eds. Elsevier, Inc., San Diego, CA 2007.
448. Lu, M., Dong, K., Egan, M.E., Giebisch, G.H., Boulpaep, E.L. and Hebert, S.C. Mouse cystic
fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proc. Nat’l. Acad. Sci. 107 (13):6082-6087, 2010.
449. Kahle, K.T., A.M., Rinehart, J., Giebisch, G., Gamba, G., Hebert S.C. and Lifton, R.P. A
novel protein kinase signaling pathway essential for blood pressure regulation in humans. Trends in Endocrinol. & Metabolism 19(3): 91-95, 2008.
450. Malnic, G., Muto, S. and Giebisch, G. Regulation of Potassium Excretion. In: The Kidney: Physiology and Pathophysiology, Hebert S.C. and Alpern, R., eds., Elsevier, Calif., 2008, pp. 1301-1348.
451. Yan, Q., Yang, X., Cantone, A., Giebisch, G., Hebert, S. and Wang, T. Female ROMK null
mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production. AJP-Regulatory, Integrative and Comparative Physiology 295:R997-R1004, 2008.
452. Wang, W-H. and Giebisch, G. Regulation of potassium (K) handling in the renal collecting
duct. Pflugers Arch., on line, 2008. 453. Cantone, A., Yang, X., Yan, Q., Giebisch, G., Hebert, S.C. and Wang, T. Mouse model of
type II Bartter’s syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity. Am. J. Physiol. 294: F1366-F1372, 2008.
454. Wagner, C.A., Loffing-Cueni, D., Yan, Q., Schulz, N., Fakitsas, P., Carrel, M., Wang, T.,
Verrey, F., Geibel, J.P., Giebisch, G., Hebert, S.C. and Loffing, J. Mouse model of type II Bartter’s syndrome. II. Altered expression of renal sodium- and water-transporting proteins. Am. J. Physiol. 294:F1373-F1380, 2008.
455. Muto, S., Tsuruoka, S., Miyata, Y., Fujimura, A., Kusano, E., Wang, W., Seldin, D. And
Giebisch, G. Basolateral Na+/H+ exchange maintains potassium secretion during diminished sodium transport in the rabbit cortical collecting duct. Kidney Int. 75:25-30, 2009.
456. Moe, O, Giebisch, G. and Seldin, D. Logic of the Kidney. In: Genetic Diseases of the
Kidney, Lifton, R.P., Somlo, S., Giebisch, G.H., and Seldin, D.W., eds., Elsevier, San Diego, CA, Chapter 4, pp 39-76. 2009.
457. Aronson, P. and Giebisch, G. Proximal renal tubular acidosis. In: Genetic Diseases of the
Kidney, Lifton, R.P., Somlo, S., Giebisch, G.H., and Seldin, D.W., eds., Elsevier, San Diego, CA, Chapter 11, pp 199-212, 2009.
458. Giebisch, G.H. Steven C. Hebert: a personal dedication. Kidney Int. 75:3-4, 2009. 459. Knauf, H., Mutschler, E., Velazquez, H. And Giebisch, G. Torasemide significantly reduces
thiazide-induced potassium- and magnesium-loss despite supra-additive natriuresis. Eur. J. Clin. Pharmacol., 65:465-472, 2009.
460. Lin, D-H., Yue, P., Pan, C-Y., Sun, P., Zhang, X., Han, Z., Roos, M., Caplan, M., Giebisch,
G. and Wang, W. POSH stimulates the ubiquitination and clathrin-independent endocytosis of ROMK1 channels. J. Biol. Chem. 284:29614-29624, 2009.
461. Watschinger, B. and Giebisch, G. Laudatio auf Prof. Dr. Gerhard Giebisch anlässlich der
Verleihung der Ehrenmitgliedschaft der ÖGIM. Wiener klin. Wochenschrift 15-16/2008:514-517, 2009.
462. Yue, P., Lin, D-H., Pan, C-Y., Leng, Q., Giebisch, G. and Wang, W-H. Src family protein
tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels. Proc. Natl. Acad. Sci. 106:15061-15066, 2009.
463. Stanton, B.A. and Giebisch, G.H. Essays on APS Classic Papers: Renal Potassium
Transport: The pioneering studies of Gerhard Giebisch. Am. J. Physiol. 298:F233-F234, 2010.
464. Giebisch, G. and Wang, W-H. Potassium transport – An update. J. Nephrol., 23: (S16): S97-
S104, 2010. 465. Giebisch, G. A long affair with renal tubules. Annual Review of Physiology, 73:1-28, 2011. 466. Aronson, P.S. and Giebisch, G. Effects of pH on Potassium: New Explanations for Old
Observations. Journal of American Society of Nephrology 22:1981-1989, 2011. 467. Wagner, C.A., Mohebbi, N., Uhlig, U., Giebisch, G.H., Breton, S., Brown, D. and Geibel, J.P.
Angiotensin II stimulates H+-ATPase activity in intercalated cells from isolated mouse connecting tubules and cortical collecting ducts. Cellular Physiology and Biochemistry 28:513-520, 2011.
468. Malnic, G., Giebisch, G., Muto, S., Wang, W., Bailey, M.A., and Satlin, L.M. Regulation of
K+ excretion. In The Kidney: Physiology and Pathophysiology, 5th edition. R. J. Alpern, O. W. Moe and M. Caplan, eds. Elsevier, Inc., San Diego, CA. In press, 2012.
469. Giebisch, G.H. and Wingo, C.S. Renal K Homeostasis: A Short Historical Perspective.
![[Clarinet_Institute] Klose 25 Daily Exercises for Sax.pdf](https://static.documents.pub/doc/80x56/545aa489b1af9f40378b59d2/clarinetinstitute-klose-25-daily-exercises-for-saxpdf.jpg)
![[Clarinet_Institute] Klose 25 Daily Exercises for Sax(1).pdf](https://static.documents.pub/doc/80x56/56d6bcec1a28ab30168c01cc/clarinetinstitute-klose-25-daily-exercises-for-sax1pdf.jpg)
