CCurriculum urriculum VVitaeitae

Dr. Christian Arnold

PERSONAL INFORMATION

Date of Birth: 22.07.1984

Place of Birth: Borna

Nationality: German

Marital status: unmarried, no children

Address: Arthur-Hoffmann-Straße 25, 04107 Leipzig

Phone: 0160 / 2170407

E-Mail: chrarnold@web.de

UNIVERSITY EDUCATION

10/2009 – 02/2014 Doctorate at the Interdisciplinary Centre for Bioinformatics (IZBI) and the Professur für Bioinformatik, Leipzig University

Topic of the dissertation: „The Eukaryotic Chromatin Computer – Components, Mode of Action, Properties, Tasks, Computational Power, and Disease Relevance“

Degree: Doctorate of Natural Sciences (Dr. rer. nat.) with grade summa cum laude (distinguished, 0)

10/2003 – 06/2008 Study of computer science with a focus on life sciences and bioinformatics, Leipzig University

Topic of the diploma thesis: „Phylogenetic Targeting: A Systematic Approach and  Computer  Program   for  Targeting  Research  Effort   in  Comparative  Evolutionary  Biology“

Degree: Computer scientist (Diplom-Informatiker – Dipl.-Inf.) with grade 1.2 (A)

SCHOOL EDUCATION

08/1996 – 07/2003 Secondary school (Gymnasium) at Rudolf-Hildebrand-Schule, Markkleeberg

Degree: Abitur with grade 1.8

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SELECTED PROFESSIONAL EXPERIENCE (INCLUDING STAYS ABROAD)

Staff Bioinformaticiansince 10/2014

European Molecular Biology Laboratory, Heidelberggeneral Bioinformatics (e.g. RNA-Seq data analysis, programming, statistical analyses, guidance)

Research Associate01/2014 – 03/2014

Leipzig University (Interdisciplinary Centre for Bioinformatics – IZBI)several bioinformatics projects (e.g., mapping of genomic coordinates between species, completion of existing projects)

Research Associate12/2011 – 01/2013

Leipzig University (Institute for Medical Informatics, Statistics and Epidemiology – IMISE)Reconstructing the evolution of t(14;18)-positive lymphomas

Guest Researchersince 11/2011

Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig (RNomics group)Evaluation of microarray data of Alzheimer's disease, design of custom expression microarrays

Employeesince 11/2009

Privatinstitut Dr. MatzPerson responsible for the IT and all IT-related tasks as well as project implementation (e.g., website creation and maintenance, video editing and creation of custom DVDs, data backup)

Research Associate and Doctoral Candidate10/2009 – 02/2014

Leipzig University (Interdisciplinary Centre for Bioinformatics – IZBI)Research in the area of epigenetics, algorithm development, simulation and evaluation of biological models and hypotheses, genome annotations, gene regulation, non-coding RNAs

automated processing, analysis, and evaluation of complex data via custom bioinformatics pipelines

Person responsible for the website of the Professur für Bioinformatik (departmental website) from 05/2011 – 02/2014

Teaching experience (giving lectures, exercise instructor, supervising a diploma thesis, tutor at the summer school Programming for Evolutionary Biology)

Research Associate08/2009 – 08/2013

Harvard University, Cambridge, MA, USA (Department of Human Evolutionary Biology)Continuation and extension of existing projects such as the 10kTrees Project (http://10ktrees.fas.harvard.edu)

Research Fellow and Lab Manager08/2008 – 07/2009

Harvard University, Cambridge, MA, USA (Department of Human Evolutionary Biology)Lab manager, general bioinformatics, working with databases, programming, phylogenetics, basic research in the field of „phylogenetic comparative methods“

Research Associate and Graduate Student05/2007 – 06/2008

Max Planck Institute for Evolutionary Anthropology, Leipzig (Department of Primatology)general bioinformatics with a particular focus on phylogenetics and the genetics of sleep

Student Assistant04/2006 – 03/2007

Leipzig University (Faculty of Mathematics and Computer Science)Correction of the exercises of the lectures „Analytical Geometry“ and „Introduction to Linear Algebra“

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LANGUAGE SKILLS

German native language

English business fluent speaking and writing skills

French fluent speaking and writing skills

SELECTED COMPUTER LITERACY

Programming and scripting languages

several years of work experience in R, Perl, C, PHP, AWK, HTML, SQL, CSS, JavaScript and Java

Operating systems several years of work experience with Linux, Windows and Mac OS

Office several years of work experience in MS Office (Word, Excel, Powerpoint), LibreOffice / OpenOffice (Writer, Calc, Draw), LaTeX

Image processing and drawing programs

several years of work experience in LibreOffice Draw, GIMP, CorelDraw

Databases several years of work experience in SQL

General capabilities Algorithm development with a particular focus on performance; automated, database-assisted or custom bioinformatics pipeline-controlled evaluation of complex biological data; data visualization; automated statistical evaluation; fast learning of new technologies and capabilities

FURTHER EDUCATION, QUALIFIKATIONS & AWARDS

05/10 Privatinstitut Dr. MatzParticipation at a two-day training seminar with the topic „Acting strongly and persuasively in complex situations” (Content: Improvement of decision-making and responsibility in different work-related situations, identification of developmental potential)

07/08 Leipzig University Best of class 2008 (Computer Science)

since 05/2002 Driving licence class B

LEISURE

Hobbies playing chess, learning languages and language tandem, volleyball, creative work (in particular with pictures), learning new capabilities and competences, traveling

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PUBLICATIONS AND PUBLICATIONS IN PREPARATION

[1]   Fritz J, Hummel J, Kienzle E, Arnold C, Nunn CL, Clauss M. 2009. Comparative chewing efficiency in mammalian herbivores. Oikos 118:1623-1632.

[2] Nunn CL, Arnold C, Matthews LJ, Borgerhoff Mulder M. 2010. Simulating Trait Evolution for Cross-Cultural Comparison. Philosophical Transactions of the Royal Society of London B 365:3807-3819.

[3] Arnold C, Nunn CL. 2010. Phylogenetic Targeting of Research Effort in Evolutionary Biology. American Naturalist 176:601-612.

[4] Arnold C, Stadler, PF. 2010. Polynomial algorithms for the Maximal Pairing Problem: Efficient phylogenetic targeting on arbitrary trees. Algorithms for Molecular Biology 5:25.

[5] Arnold C, Matthews LJ, Nunn CL. 2010. The 10kTrees Website: A New Online Resource for Primate Phylogeny. Evolutionary Anthropology 19:114-118.

[6] Matthews LJ, Arnold C, Machanda Z, Nunn CL. 2011 Primate extinction risk and historical patterns of speciation and extinction in relation to body mass. Proc. R. Soc. B. 278(1709): 1256-1263.

[7]   Nunn CL, Ezenwa VO, Arnold C, Koenig W. 2011. Mutualism or parasitism? Using a phylogenetic approach to characterize the oxpecker-ungulate relationship. Evolution 65(5):1297-304.

[8] Arnold C, Stadler PF, Prohaska SJ. 2013. Chromatin Computation: Epigenetic Inheri-tance as a Pattern Reconstruction Problem. Journal of Theoretical Biology 336(7): 61-74.

[9] Arnold C, Externbrink F, Hackermüller J, Reiche K. 2013. Design of Custom Expression Microarrays in the Post-ENCODE Era. Journal of Biotechnology 189:154–156.

[10] Löffler M, Kreuz M, Haake A, Hasenclever D, Trautmann H, Arnold C, Winter W, Klapper W, Scholtysik R, Rosolowski M, Hoffmann S, Ammerpohl O, Szczepanowski M, Herrmann D, Küppers R, Pott C, Siebert R. 2014. Genomic and epigenomic co-evolution in follicular lymphomas. Leukemia doi: 10.1038/leu.2014.209. [Epub ahead of print].

[11] Arnold C, Stadler PF, Prohaska SJ. 2014. The Eukaryotic Chromatin Computer: Tasks, Components, Properties, Computational Power. in preparation.

[12] Arnold C, Stadler PF, Hackermüller J, Reiche K, Arendt T, Überham U. 2014. Diverse Differential Expression of Chromatin-Associated Transcripts in Alzheimer's Disease. in preparation.

CONFERENCES, TALKS, LECTURES AND SEMINARS

Since 2009, I participated at eleven conferences in five different countries. I presented own performances to other participants at nine conferences (talk or poster presentation). In addition, I gave several lectures and attended an academic summer school as a tutor. A complete list of all visited conferences, conference contributions, talks, and own courses/seminars is available upon request.

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