Cutaneous Manifestation of Cardiovascular Disease

Done byMohammad Binhussein

Dermatologists may be the first physician to diagnose an underlying cardiovascular disease

skin findings inaddition to general dermatologic signs

suggestive of cardiovasculardisease

1. Infective endocarditis2. Acute rheumatic fever3. Cholesterol embolization syndrome4. Lipid disorders5. Kawasaki disease6. Pseudoxanthoma elasticum

Infective endocarditis

Osler nodes

Infective endocarditis

Janeway lesions

Risk Factor?

heart valvesdegenerative valve diseaseprosthetic valvesintravenous drug userecent cardiac or dental surgerymitral valve prolapse and rheumatic heart disease

Causative Organism?

Usually caused by viridans streptococci & staphylococci

postinfectious sequela of a group A β-hemolytic streptococcal pharyngitis

Acute rheumatic fever

Acute rheumatic fever

Erythema marginatum

Cholesterol embolization syndrome

Livedo reticularis

Describe?

red or blue, mottled, netlike discoloration

Xanthelasma

Lipid Disorder

soft yellow macules or plaques

Describe?

Premature development may indicate familial hypercholesterolemia

Pseudoxanthoma elasticum

genetic disorder ofconnective tissue affecting the skin,

eyes, and cardiovascular

plucked chicken skin

Kawasaki

immune-mediated vasculitismucocutaneous lymph node syndromefever lasting 5 or more days without explanation combinedwith at least 4 of the 5 principal clinical features, as follows:

(1 )bilateral conjunctival injection, (2) oral mucous membranechanges, (3) peripheral extremity changes, (4) polymorphousrash, and (5) cervical lymphadenopathy

LEOPARD syndrome

The lentigines are dark brown irregularly shaped macules ranging in size from pinpoint to 5 cm with involvement of the face, neck, and upper trunk

Cardiocutaneous lentiginosis syndrome and multiple lentigines syndrome, is an autosomal dominant disorder of variable penetrance

stands for Lentigines, ECG changes, Ocular telorism, Pulmonary valve stenosis, Abnormal genitalia, Retardation of growth, and Deafness.