Low-Cost Miniature Fiber-Optic Extrinsic Fabry-Perot Interferometric Pressure Sensor

for Biomedical Applications

[European Conference on Biomedical Optics, 2013]

Sven Poeggel, Daniele Tosi, Gabriel Leen, Elfed Lewis

University of Limerick, IrelandOptical Fibre Sensors Research Centre (OFSRC)

Problem

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

In-vivo pressure measurementHigh accuracy (1 mmHg or below)Minimum invasiveness (size, weight)Low-cost disposable probeImmunity to EMI

FIBER-OPTIC

Extrinsic FP Interferometer

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

EFPI: Fiber-optic Fabry-Perot interferometric sensor based on all-silica glass structure: (1) launch fiber, (2) diaphragm, (3) capillary + FBG

Capillary

Launch SM fiber

Diaphragm MM fiber

AIR-GAP

dL

FiberBragg

Grating(FBG)

Air-gap length LFP Spectrum ~ S0 + k cos[4πL/λ]

d Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

EFPI principle

L

Pressure

Air-gap length L = L0 - Sp ΔPFP Spectrum ~ S0 + k cos[4π(L - Sp

ΔP)/λ]Temperature: L = L0 - Sp ΔP + ST ΔT ⇒ FBG

L0 - Sp ΔP

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

EFPI principle

L

EFPI/FBG spectrum

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

EFPI

FBG

FBG FBG detectiondetection

EFPI/FBG system

ASE sourceASE source

SpectrometeSpectrometerr

1530-1600 nm

1520-1596 nm

CouplerCoupler

3 dB1x4 switch

ServerServer

EFPI

EFPI

EFPI

EFPI+FBG

DAQ DAQ (LabVIEW)(LabVIEW) Pressure

Temperature

} Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

EFPI EFPI detectiondetection

Probe Probe calibrationcalibration

Performance chartUL

EFPI/FBGDruck

DPI 601

St. JudePressureW

ire

Opsens OPP-M

Technology

Fiber optic,

EFPI/FBGFluidic Guidewire

Fiber optic, EFPI

Diameter 0.2 mm (>1 mm) 0.35 mm 0.55 mm

Accuracy 0.2 mmHg 2 mmHg 2 mmHg 2 mmHg

Speed 100 Hz 50 Hz 25 Hz 20/250 Hz

Stability0.6

mmHg/hr2.6

mmHg/hr>5

mmHg/hr4.0

mmHg/hr

Temperature

Compens. 0.5°C

None None None

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

Burette test

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

Burette test

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

RMSE = 2.29 mmH2O = = 0.21 mmHg

Heart simulator

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

Heart simulator

Interrogator/processing

Heart pumping

Sensor positioning

(short access)

EFPI spectrumPressure meas.

Spectrometer

ASE source

Heart pumping inle

tFiber inlet

Heart simulator

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

QuickTime™ and a decompressor

are needed to see this picture.

QuickTime™ and a decompressor

are needed to see this picture.

Time (s)

Pressure (mmHg)

Ventricular assist

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

Polymer Core,Cleveland Clinic, US

Mar 2013FPI positioningVentricular

assist

Reference (fluidic)

Pressure readout

Ventricular assist

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick

Pressure (mmHg)

QuickTime™ and a decompressor

are needed to see this picture.

QuickTime™ and a decompressor

are needed to see this picture.

Polymer Core,Cleveland Clinic, US

Mar 2013

Daniele Tosi - Optical Fibre Sensors Research Centre - project portfolio - UL2013

Urodynamics

InterrogatorInterrogator

Differential pressure measurement

Bladder outlet obstruction (BOO) diagnostic

Daniele Tosi - Optical Fibre Sensors Research Centre - project portfolio - UL2013

Other applicationsRobotic surgeryPressure force sensors - 2D/3D1mmHg accuracy, stability over several hours Miniature size ⍉ 125/80/(40) μm

Intra-aortic balloon (IAB) pumpingInstantaneous pressure detection1mmHg accuracy, stability over long operation timeSize, form factor, redundancy, placement (⍉ 200 μm)

Intra-chranial pressure (ICP)ICP 1 to 20 mmHg

≲0.1 mmHg accuracy, stability over minutes

Miniature size ⍉ 200/125/80 μm

Acknowledgments

‣ Cleveland Clinic and Pointec Medical

‣ FP7 Marie Curie (299985-PROBESENSE)

‣ Science Foundation Ireland (RFP/ECE2898)

‣ Enterprise Ireland (IP-2012-0166-Y)

‣ University of Limerick, MSSI and CES depts.

Daniele Tosi - Optical Fibre Sensors Research Centre (OFSRC) - University of Limerick