DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR BIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 26
1 Week 6 Proof of DNA&RNA as genetic material; Transformation experiments,
Blenders experiments. Seminar
2 Week 5 Properties of genetic material.Modern concept of gene structure.Over lapping
genes, split genes. Discussion
3 Week 6 Constitutive genes, jumping genes, Oncogenes.Types of tumors. Interactive method
4 Week 9 Physical, chemical and biological Carcinogens, chromosomal changes induced
by Carcinogen. Assignments given
Aug - 21
1 Week 6 DNA replication–various modes of replication, Meselson-Stahl’s studies on
replication.Enzymes and Proteins involved in replication. Seminar
2 Week 4 Mechanism of replication –Initiation, polymerization and temination.
Topoisomerases, DNA ligases. Procaryotic and Eucaryotic promoters. Discussion
3 Week 3 Mechanism of transcription and transcriptionalactivators. Posttranscriptional modifications.
Interactive method
4 Week 8 The genetic code. Assignments given
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR BIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working
Days
Week
No.of
Periods Per
week
Topics to be covered
Co-Curricular Activity
Sept - 23
1 Week 6 Universality of the code, redundancy of the code, the decoding system. Seminar
2 Week 4 Protein synthesis: Mechanism and role of various factors involved in Initiation,
elongation and termination of Protein Synthesis. Discussion
3 Week 6 Post translational processing of proteins. Interactive method
4 Week 7 Protein channeling and role of RNA in protein synthesis.
Assignments given
Oct- 26
1 Week 6 Regulation of gene expression at the levels of transcription and translation.
Operon concept; Regulatory genes, structural genes and repressors. Seminar
2 Week 5 Negative and Positive regulation.Regulation of lac, ara and trp operons.
Catabolite repression. Regulation of gene expression in lambda and nif operon. Discussion
3 Week 6 Semester-end Examinations
4 Week 9
Nov- 10 1 Week 5
Semester-end Examinations 2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 302: MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 22
1 Week
2 Week
3 Week
4 Week
July - 26
1 Week 6 Normal microbialflora of human body, host microbei nteractions.Infection
and infection process-routes of transmission of microbes in the body. Seminar
2 Week 5 Description and pathology of diseases caused by bacteria Discussion
3 Week 6 Streptococcus,Pneumococus, Gonococcus, Enterobacteriaceae, E.coli, Salmonella,Shigella,Pseudomonas, Klebsiella
Interactive method
4 Week 9
Proteus, Vibriocholera. Brucella, Haemophilus influenzae; Pathogenic anaerobes: Tetanus, Clostridia, Conynebacteria, Mycobacteria, Spirochaetes.
Assignments given
Aug - 21
1 Week 6 Description and pathology of diseases caused by Aspergillus, Penicillium, Mucomycosis, Blastomycosis, Microsporosis, Rhinosporidium, Epidermophyscosis.
Seminar
2 Week 4 Descriptionandpathology of diseases caused by hemoflagellates. Discussion
3 Week 3 Leishmania donavani, L.tropica, Trypanosoma gambiense; intestinal
flagellates. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 302: MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4 Week 8 Trichomonas, Giardia, Entamoebahistolytica, malarialparasites, Helminthes; Ascarislumbricoides, Hookworm, pinworm, Filarialparasites.
Seminar
Sept - 23
1 Week 6
Laboratory diagnosis of Common infective syndromes and parasitic manifestations; Methods of transmission and role of vectors-biology of vectors. (1) Housefly (2) Mosquitoes (3) sandfly. Need and significance of epidemiological studies
Discussion
2 Week 4
Epidemiological investigationsto identify adisease,Principles of chemotherapy,Anti bacterial drugs(Penicillin,Streptomycin,Sulfonamides and Polymyxins),Anti fungal drugs(Nystatin) ,and Antiviralagents, (Robovirin)Problems.
Interactive method
3 Week 6 Drug resistance and drug sensitivity.Drugresistance in bacteria. Assignments given
4 Week 7 Viral diseases:pathology and lab diagnosis of diseases caused by pox viruses;herpes virus(chickenpox-zoster);orthomyxo and paramyxo viruses; Seminar
Oct- 26
1 Week 6 Adenovirus, other respiratory viruses, (Influenza, Rhyno) viruses affecting nervous system (ex: Poliovirus, Rabiesvirus), enterovirus, reovirus, viralhepatitis, HIV.
Discussion
2 Week 5 Interferon–Nomenclature, types&classification, Inductionofinterferon, typesof inducers.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 9
Nov- 10 1 Week 5
Semester-end Examinations
2 Week 5
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 303: BIOSTATISTICS&BIOINFORMATICS Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 26
1 Week 6 Biostatistics:Measures of Central tendency and distribution–mean,median, mode,range,standard de viation,variance
Seminar
2 Week 5 Basic principles of probability theory, Bayes theorem, Normal distribution, statistical inference–Types of errors and levels of significance.
Discussion
3 Week 6 Comparison of variance (F-test), small sample test,t-test for comparison of means,chi square test.Analysis of variance–one way and two way, multiple comprises.
Interactive method
4 Week 9 .Correlation and Linear regression.intraduction to hidden markov models. Assignments given
Aug - 21
1 Week 6 Introduction to biological databases: NCBI, EMBL, EXPASY, PIR, And Pfam. Seminar
2 Week 4 Concept of World Wide Web: HTML, HTPP.Similarity measures-Euclidean, Mahalanobis distance, Editdistance, similarity matrices (PAM, BLOSUM) Searching sequenc databases using BLAST.
Discussion
3 Week 3 Pair wise sequence alignment using dynamic programming (Needleman–Wunsch & Smith–Waterman algorithms.
Interactive method
4 Week 8 Multiple sequence alignment–progressive alignment–profiles–multi dimensional dynamic programming.
Assignments given
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 303: BIOSTATISTICS&BIOINFORMATICS Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Sept - 23
1 Week 6 Genomics and proteomics: Molecular phylogenetics: Construction of phyto genetic trees using parsimony method and branch & bound method.
Seminar
2 Week 4 Clustering methods–UPGMA & neighbor-joining, Analysis of gene expression data by clustering.
Discussion
3 Week 6 Gene prediction–Statistical approaches–Similarity based approaches gene
annotation. Interactive method
4 Week 7 Fragment assembly, peptide sequencing using mass and spectroscopy data.Comparative genomics. Assignments given
Oct- 26
1 Week 6 Modeling: Protein secondary structure prediction–Chou Fasman rules– neural networks–discriminant analysis. Prediction of transmembrane segments in membrane proteins.
Seminar
2 Week 5 Protein 3Dstructure prediction–homology–threading– potential energy functions–energy minimization–molecular dynamics–simulated annealing.
Discussion
3 Week 6 Semester-end Examinations
4 Week 9
Nov- 10
1 Week 5 Semester-end Examinations
2 Week 5
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 304: MOLECULARBIOTECHNOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June
1 Week
2 Week
3 Week
4 Week
July – 26
1 Week 6 r-DNA technology-Isolation of nucleic acids,DNA sequencing maxam-Gilbert
And Di-deoxymethods. Seminar
2 Week 5 Restriction endonucleases, restriction maps Southern, Northern blotting and western blotting.
Discussion
3 Week 6 DNA finger printing, PCR-principle, types, application.
Interactive method
4 Week 9 Cloning vectors-Plasmids, Cosmids and bacteriophages. Ligases-DNA ligases, ligation of fragments with cohesive ends & bluntends. Assignments given
Aug - 21
1 Week 6 Homopolymer tailing, Cloning strategies–shot gun experiments, gene libraries.
Seminar
2 Week 4 Isolation of poly mRNA, synthesis of c-DNA,cloning of c-DNA in bacteria. Discussion
3 Week 3
Isolation of cloned genes, identification of recombinants, structural and functional analysis of recombinants.
Interactive method
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 304: MOLECULARBIOTECHNOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4 Week 8 Gene expression-expression of cloned genes in bacteria, yeast, plant and animal cells.
Seminar
Sept - 23
1 Week 6 Application of recombinant DNA technology in biology, plant, medicine, genetic diseases, gene therapy.
Discussion
2 Week 4 Genitically engineered micro organisams and intellectual property rights. Interactive method
3 Week 6 Nucleic acid probe technology, DNA micro array–printing of oligonucleotides
and PCR products on glass slides, and nitrocellulose paper. Assignments given
4 Week 7 Whole genome analysis for global patterns of gene expression using fluorescent-labelled c-DNA or end labeled RNA probes. Seminar
Oct- 26
1 Week 6 Analysis of single nucleotide polymorphism susing DNA chips. Discussion
2 Week 5 Protein microarray, advantages and disadvantages of DNA and protein microarrays. Interactive method
3 Week 6 Semester-end Examinations
4 Week 9
Nov- 10
1 Week 5 Semester-end Examinations
2 Week 5
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401: FERMENTATION TECHNOLOGY & INDUSTRIAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 An introduction to fermentation processes–the range of fermentation processes. Microorganism’s used in industrial microbiological processes–the isolation
Seminar
4 Week 8 Maintenance and strain improvement of industrially important microorganisms.
Discussion
Dec - 23
1 Week 6 Screening methods, isolation of autotrophicmutants. Interactive method
2 Week 5 Media and materials required for industrial microbiological processes, Antifoams.
Assignments given
3 Week 6 Microbial growth kinetics, batch culture, continuous culture, fed batch culture and Dual or multiple fermentations.
Seminar
4 Week 6 Inoculum development for large-scale processes. Design of fermentor. Discussion
Jan - 19
1 Week 5 Construction and maintenance of aseptic conditions. Control of various parameters.Sterilization of media.Types of fermentors and fermentations.
Interactive method
2 Week 3 Computer application in fermentation technology. Recovery and purification of fermentation products Fermentation Economics.
Assignments given
3 Week 2 Production of ethylalcohol, beer & wine. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401: FERMENTATION TECHNOLOGY & INDUSTRIAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Week 9 Enzyme probe biosensores, bio chips, Biofilms, biosurfactants,
Biotransformation, PetroleumMicrobiology. Seminar
Feb - 21
1 Week 6 Microbial leaching-role of microorganisms in the recovery of minerals (uranium, copper) from ores.
Discussion
2 Week 4 Microbial products from genetically modified (cloned) organismsex:
insulin. Interactive method
3 Week 6 Microbial groups involved in biogas production, design of digester. Assignments given
4 Week 5 Patenting: Conceptanditscomposition&protectionofrightandtheirlimitation.
Seminar
Mar - 22 1 Week 6 Intellectual propertyrights (IPR). Discussion
2 Week 5 Patentingbiotechnologyinventions.
Interactive method
3 Week 4 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 402: ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Basic concepts of Ecology and Environment–Biologicalspectrumatlevelsof organization & realm of ecology. Ecosystem–Concept, components, food chains, food webs and tropic levels.
Seminar
4 Week 8 Energy transfer efficiencies between tropic levels. Biological factors influencing the growth.
Discussion
Dec - 23
1 Week 6 Survival of microorganisms-inter reactions of microbial population andc ommunity dynamics–Growth in closed environment and in open environments.
Interactive method
2 Week 5 The kinetic properties of competition between microbial populations.Kinetic principles of prey predator relationship.
Assignments given
3 Week 6 Aquatic environment: Fresh water microorganisms, their zonation and characteristics.
Seminar
4 Week 6 Saltwater, oceans, estuaries, microorganismtheir zonation and characteristics. Discussion
Jan - 19
1 Week 5 Faecal pollution of waters–water bore diseases, indicator organisms. Interactive method
2 Week 3 IMVIC test, Determination of water potability by MPN and sanitary examination.
Assignments given
3 Week 2 Atmospheric Environment: Dispersal of airborne microorganisms. Air Sampling principles and techniques.
Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 402: ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 9 Air spora: Concepts and components, indoor and outdoor air spora. Diurnal periodicity patterns.Seasonal periodicity patterns.Verticalprofiles. Seminar
Feb - 21
1 Week 6 Microorganisms and chemical pollutants:methyl mercury,trimethyl arsine, hydrogen sulphide, acid rain water,carbon monoxide, ammonia, nitrate, nitrogen oxides, nitrosamines,Eutrophication,algaltoxins.
Discussion
2 Week 4 Microorganisms and sewagetreatment: Interactive method
3 Week 6 COD, BOD&DO, tricklingfilters, activatedsludgeprocess, oxidationponds; sludge
treatment (anaerobicdigestion). Assignments given
4 Week 5 Bioremediation Technology–Microbial degradation of oil spills, pesticides and detergents, Biofouling.
Seminar
1 Week 6
Fate of genetically engineered microorganisms in the environment. Environmental impact assessment studies.
Discussion
Mar - 22 2 Week 5 Deterioration of materials–paper, textiles, painted surfaces, prevention of microbial deterioration.
Interactive method
3 Week 4 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403: FOOD MICROBIOLOGY & AGRICULTURAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Microbiology of foods–Microbial flora of fresh foods, grains, fruits, vegetables, milk, meat,eggs and fish and their in festation by bacteria,fungi and viruses.
Seminar
4 Week 8 Microbiological examination of foods-microscopic techniques and cultural techniques.Direct microscopic examination, total colony counts and differential enumeration.
Discussion
Dec - 23
1 Week 6 Identification of specific groups–Bacteria, Viruses, Fungi and Protozoa. Interactive method
2 Week 5 Microbial spoilage of milk, food, types of spoilage organisms, food poisoning. Myco toxins and bacterial toxins.
Assignments given
3 Week 6 Food processing & preservation. Seminar
4 Week 6 Microorganisms as food–single cell protein, yeast, algae and fungal biomass production.
Discussion
Jan - 19
1 Week 5 Soil micobiology. Soil structure, soil profile, Physico-chemical conditions, Microbial composition.
Interactive method
2 Week 3 Sampling techniques. Assignments given
3 Week 2 Role of Microorganisms in organicmatter decomposition. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403: FOOD MICROBIOLOGY & AGRICULTURAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 9 Bio-geo chemical cycles–Carbon cycle, Nitrogen cycle–Nitrogen fixation. Nitrification, de-nitrification, sulpher, iron and phosphorus cycles. Seminar
Feb - 21
1 Week 6 Rhizosphere–Rhizosphere Microorganisms, Biochelators (Siderophores).
Discussion
2 Week 4 Biofertilizers–Introduction, biofertilizers using nitrogen fixing microbes. Interactive method
3 Week 6 Phosphate solubilization-Rhizobium, Azato bacter, Azospirillum Assignments given
4 Week 5 Soil bactria-Anabaena Symbiosis. Seminar
1 Week 6
Blue green algae, Mycorrihiza, Biopesticides–toxins from Bacillus thuringiensis.
Discussion
Mar - 22 2 Week 5 Psuedomonas syringae, Biological Control–Use of Baculovirus, NPV virus, protozoa & fungi in biological control.
Interactive method
3 Week 4 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 404: PHARMACEUTICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13 3 Week 5 Chemical disinfectants, antiseptics and preservatives. Seminar
4 Week 8 Antifungal antibiotics, Production of antibiotics–Penicillin, Streptomycin. Discussion
Dec - 23
1 Week 6 Erythromycin, bacitracin and tetracycline. Interactive method
2 Week 5 Mechanism of action of antibiotics–the bacterial cell wall, protein synthesis, chromosome function & replication. Assignments given
3 Week 6 Bacterial resistence to antibiotics –intrinsic & acquired resistence, biochemical mechanisam of resistance.
Seminar
4 Week 6 Assay of antibiotics–Penicillin, Streptomycin. Discussion
Jan - 19
1 Week 5 Industrial Production of Enzymes–amylases, Proteases. Interactive method
2 Week 3 Organic acids-lactic acid, citric acid. Assignments given
3 Week 2 Amino acids–L-lysine, L-glutamicacid; Food supplements and hormones. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2013-14
Department: P.G.MICROBIOLIGY Paper: MB: 404: PHARMACEUTICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 9 Production of VitaminB12. Microbial transformation of sterioids & non sterioids. Seminar
Feb - 21
1 Week 6 Analytical Microbiology–microbiological assays of Vitamins (Riboflavin, B12). Discussion
2 Week 4 Microbiological assays of Aminoacids (lysine, tryptophan). Interactive method
3 Week 6 Ecology of Microorganisms as it effectsthe pharmaceutical industry. Assignments given
4 Week 5 Microbial spoilage &preservation of medicines using antimicrobial agents. Seminar
1 Week 6 Control of microbial risk in medicines.
Discussion
Mar - 22 2 Week 5 Contamination of non-sterile pharmaceuticals in hospital & community environments.
Interactive method
3 Week 4 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR BIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Proof of DNA&RNA as genetic material; Transformation experiments,
Blenders experiments. Seminar
2 Week 5 Properties of genetic material.Modern concept of gene structure.Over lapping
genes, split genes. Discussion
3 Week 6 Constitutive genes, jumping genes, Oncogenes.Types of tumors. Interactive method
4 Week 8 Physical, chemical and biological Carcinogens, chromosomal changes induced
by Carcinogen. Assignments given
Aug - 21
1 Week 6 DNA replication–various modes of replication, Meselson-Stahl’s studies on
replication.Enzymes and Proteins involved in replication. Seminar
2 Week 4 Mechanism of replication –Initiation, polymerization and temination.
Topoisomerases, DNA ligases. Procaryotic and Eucaryotic promoters. Discussion
3 Week 4 Mechanism of transcription and transcriptionalactivators. Posttranscriptional modifications.
Interactive method
4 Week 7 The genetic code. Assignments given
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR BIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working
Days
Week
No.of
Periods Per
week
Topics to be covered
Co-Curricular Activity
Sept - 23
1 Week 6 Universality of the code, redundancy of the code, the decoding system. Seminar
2 Week 5 Protein synthesis: Mechanism and role of various factors involved in Initiation,
elongation and termination of Protein Synthesis. Discussion
3 Week 6 Post translational processing of proteins. Interactive method
4 Week 6 Protein channeling and role of RNA in protein synthesis.
Assignments given
Oct- 19
1 Week 1 Regulation of gene expression at the levels of transcription and translation.
Operon concept; Regulatory genes, structural genes and repressors. Seminar
2 Week 5 Negative and Positive regulation.Regulation of lac, ara and trp operons.
Catabolite repression. Regulation of gene expression in lambda and nif operon. Discussion
3 Week 6 Semester-end Examinations
4 Week 7
Nov- 10 1 Week 5
Semester-end Examinations 2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 302: MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Normal microbialflora of human body, host microbei nteractions.Infection
and infection process-routes of transmission of microbes in the body. Seminar
2 Week 5 Description and pathology of diseases caused by bacteria Discussion
3 Week 6 Streptococcus,Pneumococus, Gonococcus, Enterobacteriaceae, E.coli, Salmonella,Shigella,Pseudomonas, Klebsiella
Interactive method
4 Week 8
Proteus, Vibriocholera. Brucella, Haemophilus influenzae; Pathogenic anaerobes: Tetanus, Clostridia, Conynebacteria, Mycobacteria, Spirochaetes.
Assignments given
Aug - 21
1 Week 6 Description and pathology of diseases caused by Aspergillus, Penicillium, Mucomycosis, Blastomycosis, Microsporosis, Rhinosporidium, Epidermophyscosis.
Seminar
2 Week 4 Descriptionandpathology of diseases caused by hemoflagellates. Discussion
3 Week 4 Leishmania donavani, L.tropica, Trypanosoma gambiense; intestinal
flagellates. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 302: MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4 Week 7 Trichomonas, Giardia, Entamoebahistolytica, malarialparasites, Helminthes; Ascarislumbricoides, Hookworm, pinworm, Filarialparasites.
Seminar
Sept - 23
1 Week 6
Laboratory diagnosis of Common infective syndromes and parasitic manifestations; Methods of transmission and role of vectors-biology of vectors. (1) Housefly (2) Mosquitoes (3) sandfly. Need and significance of epidemiological studies
Discussion
2 Week 5
Epidemiological investigationsto identify adisease,Principles of chemotherapy,Anti bacterial drugs(Penicillin,Streptomycin,Sulfonamides and Polymyxins),Anti fungal drugs(Nystatin) ,and Antiviralagents, (Robovirin)Problems.
Interactive method
3 Week 6 Drug resistance and drug sensitivity.Drugresistance in bacteria. Assignments given
4 Week 6 Viral diseases:pathology and lab diagnosis of diseases caused by pox viruses;herpes virus(chickenpox-zoster);orthomyxo and paramyxo viruses; Seminar
Oct- 19
1 Week 1 Adenovirus, other respiratory viruses, (Influenza, Rhyno) viruses affecting nervous system (ex: Poliovirus, Rabiesvirus), enterovirus, reovirus, viralhepatitis, HIV.
Discussion
2 Week 5 Interferon–Nomenclature, types&classification, Inductionofinterferon, typesof inducers.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Nov- 10 1 Week 5
Semester-end Examinations
2 Week 5
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 303: BIOSTATISTICS&BIOINFORMATICS Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Biostatistics:Measures of Central tendency and distribution–mean,median, mode,range,standard de viation,variance
Seminar
2 Week 5 Basic principles of probability theory, Bayes theorem, Normal distribution, statistical inference–Types of errors and levels of significance.
Discussion
3 Week 6 Comparison of variance (F-test), small sample test,t-test for comparison of means,chi square test.Analysis of variance–one way and two way, multiple comprises.
Interactive method
4 Week 8 .Correlation and Linear regression.intraduction to hidden markov models. Assignments given
Aug - 21
1 Week 6 Introduction to biological databases: NCBI, EMBL, EXPASY, PIR, And Pfam. Seminar
2 Week 4 Concept of World Wide Web: HTML, HTPP.Similarity measures-Euclidean, Mahalanobis distance, Editdistance, similarity matrices (PAM, BLOSUM) Searching sequenc databases using BLAST.
Discussion
3 Week 4 Pair wise sequence alignment using dynamic programming (Needleman–Wunsch & Smith–Waterman algorithms.
Interactive method
4 Week 7 Multiple sequence alignment–progressive alignment–profiles–multi dimensional dynamic programming.
Assignments given
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 303: BIOSTATISTICS&BIOINFORMATICS Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Sept - 23
1 Week 6 Genomics and proteomics: Molecular phylogenetics: Construction of phyto genetic trees using parsimony method and branch & bound method.
Seminar
2 Week 5 Clustering methods–UPGMA & neighbor-joining, Analysis of gene expression data by clustering.
Discussion
3 Week 6 Gene prediction–Statistical approaches–Similarity based approaches gene
annotation. Interactive method
4 Week 6 Fragment assembly, peptide sequencing using mass and spectroscopy data.Comparative genomics. Assignments given
Oct- 19
1 Week 1 Modeling: Protein secondary structure prediction–Chou Fasman rules– neural networks–discriminant analysis. Prediction of transmembrane segments in membrane proteins.
Seminar
2 Week 5 Protein 3Dstructure prediction–homology–threading– potential energy functions–energy minimization–molecular dynamics–simulated annealing.
Discussion
3 Week 6 Semester-end Examinations
4 Week 7
Nov- 10
1 Week 5 Semester-end Examinations
2 Week 5
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 304: MOLECULARBIOTECHNOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June
1 Week
2 Week
3 Week
4 Week
July – 25
1 Week 6 r-DNA technology-Isolation of nucleic acids,DNA sequencing maxam-Gilbert
And Di-deoxymethods. Seminar
2 Week 5 Restriction endonucleases, restriction maps Southern, Northern blotting and western blotting.
Discussion
3 Week 6 DNA finger printing, PCR-principle, types, application.
Interactive method
4 Week 8 Cloning vectors-Plasmids, Cosmids and bacteriophages. Ligases-DNA ligases, ligation of fragments with cohesive ends & bluntends. Assignments given
Aug - 21
1 Week 6 Homopolymer tailing, Cloning strategies–shot gun experiments, gene libraries.
Seminar
2 Week 4 Isolation of poly mRNA, synthesis of c-DNA,cloning of c-DNA in bacteria. Discussion
3 Week 4
Isolation of cloned genes, identification of recombinants, structural and functional analysis of recombinants.
Interactive method
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 304: MOLECULARBIOTECHNOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4 Week 7 Gene expression-expression of cloned genes in bacteria, yeast, plant and animal cells.
Seminar
Sept - 23
1 Week 6 Application of recombinant DNA technology in biology, plant, medicine, genetic diseases, gene therapy.
Discussion
2 Week 5 Genitically engineered micro organisams and intellectual property rights. Interactive method
3 Week 6 Nucleic acid probe technology, DNA micro array–printing of oligonucleotides
and PCR products on glass slides, and nitrocellulose paper. Assignments given
4 Week 6 Whole genome analysis for global patterns of gene expression using fluorescent-labelled c-DNA or end labeled RNA probes. Seminar
Oct- 19
1 Week 1 Analysis of single nucleotide polymorphism susing DNA chips. Discussion
2 Week 5 Protein microarray, advantages and disadvantages of DNA and protein microarrays. Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Nov- 10
1 Week 5 Semester-end Examinations
2 Week 5
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401: FERMENTATION TECHNOLOGY & INDUSTRIAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 6 An introduction to fermentation processes–the range of fermentation processes. Microorganism’s used in industrial microbiological processes–the isolation
Seminar
4 Week 7 Maintenance and strain improvement of industrially important microorganisms.
Discussion
Dec - 24
1 Week 6 Screening methods, isolation of autotrophicmutants. Interactive method
2 Week 5 Media and materials required for industrial microbiological processes, Antifoams.
Assignments given
3 Week 6 Microbial growth kinetics, batch culture, continuous culture, fed batch culture and Dual or multiple fermentations.
Seminar
4 Week 7 Inoculum development for large-scale processes. Design of fermentor. Discussion
Jan - 17
1 Week 5 Construction and maintenance of aseptic conditions. Control of various parameters.Sterilization of media.Types of fermentors and fermentations.
Interactive method
2 Week 2 Computer application in fermentation technology. Recovery and purification of fermentation products Fermentation Economics.
Assignments given
3 Week 3 Production of ethylalcohol, beer & wine. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401: FERMENTATION TECHNOLOGY & INDUSTRIAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Week 7 Enzyme probe biosensores, bio chips, Biofilms, biosurfactants,
Biotransformation, PetroleumMicrobiology. Seminar
Feb - 22
1 Week 6 Microbial leaching-role of microorganisms in the recovery of minerals (uranium, copper) from ores.
Discussion
2 Week 5 Microbial products from genetically modified (cloned) organismsex:
insulin. Interactive method
3 Week 5 Microbial groups involved in biogas production, design of digester. Assignments given
4 Week 6 Patenting: Conceptanditscomposition&protectionofrightandtheirlimitation.
Seminar
Mar - 22 1 Week 5 Intellectual propertyrights (IPR). Discussion
2 Week 5 Patentingbiotechnologyinventions.
Interactive method
3 Week 5 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 402: ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 6 Basic concepts of Ecology and Environment–Biologicalspectrumatlevelsof organization & realm of ecology. Ecosystem–Concept, components, food chains, food webs and tropic levels.
Seminar
4 Week 7 Energy transfer efficiencies between tropic levels. Biological factors influencing the growth.
Discussion
Dec - 24
1 Week 6 Survival of microorganisms-inter reactions of microbial population andc ommunity dynamics–Growth in closed environment and in open environments.
Interactive method
2 Week 5 The kinetic properties of competition between microbial populations.Kinetic principles of prey predator relationship.
Assignments given
3 Week 6 Aquatic environment: Fresh water microorganisms, their zonation and characteristics.
Seminar
4 Week 7 Saltwater, oceans, estuaries, microorganismtheir zonation and characteristics. Discussion
Jan - 17
1 Week 5 Faecal pollution of waters–water bore diseases, indicator organisms. Interactive method
2 Week 2 IMVIC test, Determination of water potability by MPN and sanitary examination.
Assignments given
3 Week 3 Atmospheric Environment: Dispersal of airborne microorganisms. Air Sampling principles and techniques.
Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 402: ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 7 Air spora: Concepts and components, indoor and outdoor air spora. Diurnal periodicity patterns.Seasonal periodicity patterns.Verticalprofiles. Seminar
Feb - 22
1 Week 6 Microorganisms and chemical pollutants:methyl mercury,trimethyl arsine, hydrogen sulphide, acid rain water,carbon monoxide, ammonia, nitrate, nitrogen oxides, nitrosamines,Eutrophication,algaltoxins.
Discussion
2 Week 5 Microorganisms and sewagetreatment: Interactive method
3 Week 5 COD, BOD&DO, tricklingfilters, activatedsludgeprocess, oxidationponds; sludge
treatment (anaerobicdigestion). Assignments given
4 Week 6 Bioremediation Technology–Microbial degradation of oil spills, pesticides and detergents, Biofouling.
Seminar
1 Week 5
Fate of genetically engineered microorganisms in the environment. Environmental impact assessment studies.
Discussion
Mar - 22 2 Week 5 Deterioration of materials–paper, textiles, painted surfaces, prevention of microbial deterioration.
Interactive method
3 Week 5 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403: FOOD MICROBIOLOGY & AGRICULTURAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 6 Microbiology of foods–Microbial flora of fresh foods, grains, fruits, vegetables, milk, meat,eggs and fish and their in festation by bacteria,fungi and viruses.
Seminar
4 Week 7 Microbiological examination of foods-microscopic techniques and cultural techniques.Direct microscopic examination, total colony counts and differential enumeration.
Discussion
Dec - 24
1 Week 6 Identification of specific groups–Bacteria, Viruses, Fungi and Protozoa. Interactive method
2 Week 5 Microbial spoilage of milk, food, types of spoilage organisms, food poisoning. Myco toxins and bacterial toxins.
Assignments given
3 Week 6 Food processing & preservation. Seminar
4 Week 7 Microorganisms as food–single cell protein, yeast, algae and fungal biomass production.
Discussion
Jan - 17
1 Week 5 Soil micobiology. Soil structure, soil profile, Physico-chemical conditions, Microbial composition.
Interactive method
2 Week 2 Sampling techniques. Assignments given
3 Week 3 Role of Microorganisms in organicmatter decomposition. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403: FOOD MICROBIOLOGY & AGRICULTURAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 7 Bio-geo chemical cycles–Carbon cycle, Nitrogen cycle–Nitrogen fixation. Nitrification, de-nitrification, sulpher, iron and phosphorus cycles. Seminar
Feb - 22
1 Week 6 Rhizosphere–Rhizosphere Microorganisms, Biochelators (Siderophores).
Discussion
2 Week 5 Biofertilizers–Introduction, biofertilizers using nitrogen fixing microbes. Interactive method
3 Week 5 Phosphate solubilization-Rhizobium, Azato bacter, Azospirillum Assignments given
4 Week 6 Soil bactria-Anabaena Symbiosis. Seminar
1 Week 5
Blue green algae, Mycorrihiza, Biopesticides–toxins from Bacillus thuringiensis.
Discussion
Mar - 22 2 Week 5 Psuedomonas syringae, Biological Control–Use of Baculovirus, NPV virus, protozoa & fungi in biological control.
Interactive method
3 Week 5 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 404: PHARMACEUTICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13 3 Week 6 Chemical disinfectants, antiseptics and preservatives. Seminar
4 Week 7 Antifungal antibiotics, Production of antibiotics–Penicillin, Streptomycin. Discussion
Dec – 24
1 Week 6 Erythromycin, bacitracin and tetracycline. Interactive method
2 Week 5 Mechanism of action of antibiotics–the bacterial cell wall, protein synthesis, chromosome function & replication. Assignments given
3 Week 6 Bacterial resistence to antibiotics –intrinsic & acquired resistence, biochemical mechanisam of resistance.
Seminar
4 Week 7 Assay of antibiotics–Penicillin, Streptomycin. Discussion
Jan – 17
1 Week 5 Industrial Production of Enzymes–amylases, Proteases. Interactive method
2 Week 2 Organic acids-lactic acid, citric acid. Assignments given
3 Week 3 Amino acids–L-lysine, L-glutamicacid; Food supplements and hormones. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2014-15
Department: P.G.MICROBIOLIGY Paper: MB: 404: PHARMACEUTICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 7 Production of VitaminB12. Microbial transformation of sterioids & non sterioids. Seminar
Feb – 22
1 Week 6 Analytical Microbiology–microbiological assays of Vitamins (Riboflavin, B12). Discussion
2 Week 5 Microbiological assays of Aminoacids (lysine, tryptophan). Interactive method
3 Week 5 Ecology of Microorganisms as it effectsthe pharmaceutical industry. Assignments given
4 Week 6 Microbial spoilage &preservation of medicines using antimicrobial agents. Seminar
1 Week 5 Control of microbial risk in medicines.
Discussion
Mar - 22 2 Week 5 Contamination of non-sterile pharmaceuticals in hospital & community environments.
Interactive method
3 Week 5 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR BIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Proof of DNA&RNA as genetic material; Transformation experiments,
Blenders experiments. Seminar
2 Week 5 Properties of genetic material.Modern concept of gene structure.Over lapping
genes, split genes. Discussion
3 Week 5 Constitutive genes, jumping genes, Oncogenes.Types of tumors. Interactive method
4 Week 9 Physical, chemical and biological Carcinogens, chromosomal changes induced
by Carcinogen. Assignments given
Aug - 22
1 Week 6 DNA replication–various modes of replication, Meselson-Stahl’s studies on
replication.Enzymes and Proteins involved in replication. Seminar
2 Week 5 Mechanism of replication –Initiation, polymerization and temination.
Topoisomerases, DNA ligases. Procaryotic and Eucaryotic promoters. Discussion
3 Week 5 Mechanism of transcription and transcriptionalactivators. Posttranscriptional modifications.
Interactive method
4 Week 6 The genetic code. Assignments given
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR BIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working
Days
Week
No.of
Periods Per
week
Topics to be covered
Co-Curricular Activity
Sept - 23
1 Week 5 Universality of the code, redundancy of the code, the decoding system. Seminar
2 Week 5 Protein synthesis: Mechanism and role of various factors involved in Initiation,
elongation and termination of Protein Synthesis. Discussion
3 Week 5 Post translational processing of proteins. Interactive method
4 Week 8 Protein channeling and role of RNA in protein synthesis.
Assignments given
Oct- 19
1 Week 5 Regulation of gene expression at the levels of transcription and translation.
Operon concept; Regulatory genes, structural genes and repressors. Seminar
2 Week 5 Negative and Positive regulation.Regulation of lac, ara and trp operons.
Catabolite repression. Regulation of gene expression in lambda and nif operon. Discussion
3 Week 3 Semester-end Examinations
4 Week 6
Nov- 9 1 Week 5
Semester-end Examinations 2 Week 4
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 302: MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Normal microbialflora of human body, host microbei nteractions.Infection
and infection process-routes of transmission of microbes in the body. Seminar
2 Week 5 Description and pathology of diseases caused by bacteria Discussion
3 Week 5 Streptococcus,Pneumococus, Gonococcus, Enterobacteriaceae, E.coli, Salmonella,Shigella,Pseudomonas, Klebsiella
Interactive method
4 Week 9
Proteus, Vibriocholera. Brucella, Haemophilus influenzae; Pathogenic anaerobes: Tetanus, Clostridia, Conynebacteria, Mycobacteria, Spirochaetes.
Assignments given
Aug - 22
1 Week 6 Description and pathology of diseases caused by Aspergillus, Penicillium, Mucomycosis, Blastomycosis, Microsporosis, Rhinosporidium, Epidermophyscosis.
Seminar
2 Week 5 Descriptionandpathology of diseases caused by hemoflagellates. Discussion
3 Week 5 Leishmania donavani, L.tropica, Trypanosoma gambiense; intestinal
flagellates. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 302: MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4 Week 6 Trichomonas, Giardia, Entamoebahistolytica, malarialparasites, Helminthes; Ascarislumbricoides, Hookworm, pinworm, Filarialparasites.
Seminar
Sept - 23
1 Week 5
Laboratory diagnosis of Common infective syndromes and parasitic manifestations; Methods of transmission and role of vectors-biology of vectors. (1) Housefly (2) Mosquitoes (3) sandfly. Need and significance of epidemiological studies
Discussion
2 Week 5
Epidemiological investigationsto identify adisease,Principles of chemotherapy,Anti bacterial drugs(Penicillin,Streptomycin,Sulfonamides and Polymyxins),Anti fungal drugs(Nystatin) ,and Antiviralagents, (Robovirin)Problems.
Interactive method
3 Week 5 Drug resistance and drug sensitivity.Drugresistance in bacteria. Assignments given
4 Week 8 Viral diseases:pathology and lab diagnosis of diseases caused by pox viruses;herpes virus(chickenpox-zoster);orthomyxo and paramyxo viruses; Seminar
Oct- 19
1 Week 5 Adenovirus, other respiratory viruses, (Influenza, Rhyno) viruses affecting nervous system (ex: Poliovirus, Rabiesvirus), enterovirus, reovirus, viralhepatitis, HIV.
Discussion
2 Week 5 Interferon–Nomenclature, types&classification, Inductionofinterferon, typesof inducers.
Interactive method
3 Week 3 Semester-end Examinations
4 Week 6
Nov- 9 1 Week 5
Semester-end Examinations
2 Week 4
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 303: BIOSTATISTICS&BIOINFORMATICS Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Biostatistics:Measures of Central tendency and distribution–mean,median, mode,range,standard de viation,variance
Seminar
2 Week 5 Basic principles of probability theory, Bayes theorem, Normal distribution, statistical inference–Types of errors and levels of significance.
Discussion
3 Week 5 Comparison of variance (F-test), small sample test,t-test for comparison of means,chi square test.Analysis of variance–one way and two way, multiple comprises.
Interactive method
4 Week 9 .Correlation and Linear regression.intraduction to hidden markov models. Assignments given
Aug - 22
1 Week 6 Introduction to biological databases: NCBI, EMBL, EXPASY, PIR, And Pfam. Seminar
2 Week 5 Concept of World Wide Web: HTML, HTPP.Similarity measures-Euclidean, Mahalanobis distance, Editdistance, similarity matrices (PAM, BLOSUM) Searching sequenc databases using BLAST.
Discussion
3 Week 5 Pair wise sequence alignment using dynamic programming (Needleman–Wunsch & Smith–Waterman algorithms.
Interactive method
4 Week 6 Multiple sequence alignment–progressive alignment–profiles–multi dimensional dynamic programming.
Assignments given
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 303: BIOSTATISTICS&BIOINFORMATICS Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Sept - 23
1 Week 5 Genomics and proteomics: Molecular phylogenetics: Construction of phyto genetic trees using parsimony method and branch & bound method.
Seminar
2 Week 5 Clustering methods–UPGMA & neighbor-joining, Analysis of gene expression data by clustering.
Discussion
3 Week 5 Gene prediction–Statistical approaches–Similarity based approaches gene
annotation. Interactive method
4 Week 8 Fragment assembly, peptide sequencing using mass and spectroscopy data.Comparative genomics. Assignments given
Oct- 19
1 Week 5 Modeling: Protein secondary structure prediction–Chou Fasman rules– neural networks–discriminant analysis. Prediction of transmembrane segments in membrane proteins.
Seminar
2 Week 5 Protein 3Dstructure prediction–homology–threading– potential energy functions–energy minimization–molecular dynamics–simulated annealing.
Discussion
3 Week 3 Semester-end Examinations
4 Week 6
Nov- 9
1 Week 5 Semester-end Examinations
2 Week 4
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 304: MOLECULARBIOTECHNOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 10
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 r-DNA technology-Isolation of nucleic acids,DNA sequencing maxam-Gilbert
And Di-deoxymethods. Seminar
2 Week 5 Restriction endonucleases, restriction maps Southern, Northern blotting and western blotting.
Discussion
3 Week 5 DNA finger printing, PCR-principle, types, application.
Interactive method
4 Week 9 Cloning vectors-Plasmids, Cosmids and bacteriophages. Ligases-DNA ligases, ligation of fragments with cohesive ends & bluntends. Assignments given
Aug - 22
1 Week 6 Homopolymer tailing, Cloning strategies–shot gun experiments, gene libraries.
Seminar
2 Week 5 Isolation of poly mRNA, synthesis of c-DNA,cloning of c-DNA in bacteria. Discussion
3 Week 5
Isolation of cloned genes, identification of recombinants, structural and functional analysis of recombinants.
Interactive method
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 304: MOLECULARBIOTECHNOLOGY Class: MSC MICROBIOLOGY Semester: III
Signature of the Lecturer Signature of the HOD Signature of the Principal
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4 Week 6 Gene expression-expression of cloned genes in bacteria, yeast, plant and animal cells.
Seminar
Sept - 23
1 Week 5 Application of recombinant DNA technology in biology, plant, medicine, genetic diseases, gene therapy.
Discussion
2 Week 5 Genitically engineered micro organisams and intellectual property rights. Interactive method
3 Week 5 Nucleic acid probe technology, DNA micro array–printing of oligonucleotides
and PCR products on glass slides, and nitrocellulose paper. Assignments given
4 Week 8 Whole genome analysis for global patterns of gene expression using fluorescent-labelled c-DNA or end labeled RNA probes. Seminar
Oct- 19
1 Week 5 Analysis of single nucleotide polymorphism susing DNA chips. Discussion
2 Week 5 Protein microarray, advantages and disadvantages of DNA and protein microarrays. Interactive method
3 Week 3 Semester-end Examinations
4 Week 6
Nov- 9
1 Week 5 Semester-end Examinations
2 Week 4
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401: FERMENTATION TECHNOLOGY & INDUSTRIAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 An introduction to fermentation processes–the range of fermentation processes. Microorganism’s used in industrial microbiological processes–the isolation
Seminar
4 Week 8 Maintenance and strain improvement of industrially important microorganisms.
Discussion
Dec - 24
1 Week 6 Screening methods, isolation of autotrophicmutants. Interactive method
2 Week 5 Media and materials required for industrial microbiological processes, Antifoams.
Assignments given
3 Week 6 Microbial growth kinetics, batch culture, continuous culture, fed batch culture and Dual or multiple fermentations.
Seminar
4 Week 7 Inoculum development for large-scale processes. Design of fermentor. Discussion
Jan - 17
1 Week 5 Construction and maintenance of aseptic conditions. Control of various parameters.Sterilization of media.Types of fermentors and fermentations.
Interactive method
2 Week 1 Computer application in fermentation technology. Recovery and purification of fermentation products Fermentation Economics.
Assignments given
3 Week 4 Production of ethylalcohol, beer & wine. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401: FERMENTATION TECHNOLOGY & INDUSTRIAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Week 7 Enzyme probe biosensores, bio chips, Biofilms, biosurfactants,
Biotransformation, PetroleumMicrobiology. Seminar
Feb - 23
1 Week 6 Microbial leaching-role of microorganisms in the recovery of minerals (uranium, copper) from ores.
Discussion
2 Week 5 Microbial products from genetically modified (cloned) organismsex:
insulin. Interactive method
3 Week 5 Microbial groups involved in biogas production, design of digester. Assignments given
4 Week 7 Patenting: Conceptanditscomposition&protectionofrightandtheirlimitation.
Seminar
Mar - 23 1 Week 5 Intellectual propertyrights (IPR). Discussion
2 Week 5 Patentingbiotechnologyinventions.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 402: ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Basic concepts of Ecology and Environment–Biologicalspectrumatlevelsof organization & realm of ecology. Ecosystem–Concept, components, food chains, food webs and tropic levels.
Seminar
4 Week 8 Energy transfer efficiencies between tropic levels. Biological factors influencing the growth.
Discussion
Dec - 24
1 Week 6 Survival of microorganisms-inter reactions of microbial population andc ommunity dynamics–Growth in closed environment and in open environments.
Interactive method
2 Week 5 The kinetic properties of competition between microbial populations.Kinetic principles of prey predator relationship.
Assignments given
3 Week 6 Aquatic environment: Fresh water microorganisms, their zonation and characteristics.
Seminar
4 Week 7 Saltwater, oceans, estuaries, microorganismtheir zonation and characteristics. Discussion
Jan - 17
1 Week 5 Faecal pollution of waters–water bore diseases, indicator organisms. Interactive method
2 Week 1 IMVIC test, Determination of water potability by MPN and sanitary examination.
Assignments given
3 Week 4 Atmospheric Environment: Dispersal of airborne microorganisms. Air Sampling principles and techniques.
Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 402: ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 7 Air spora: Concepts and components, indoor and outdoor air spora. Diurnal periodicity patterns.Seasonal periodicity patterns.Verticalprofiles. Seminar
Feb - 23
1 Week 6 Microorganisms and chemical pollutants:methyl mercury,trimethyl arsine, hydrogen sulphide, acid rain water,carbon monoxide, ammonia, nitrate, nitrogen oxides, nitrosamines,Eutrophication,algaltoxins.
Discussion
2 Week 5 Microorganisms and sewagetreatment: Interactive method
3 Week 5 COD, BOD&DO, tricklingfilters, activatedsludgeprocess, oxidationponds; sludge
treatment (anaerobicdigestion). Assignments given
4 Week 7 Bioremediation Technology–Microbial degradation of oil spills, pesticides and detergents, Biofouling.
Seminar
1 Week 5
Fate of genetically engineered microorganisms in the environment. Environmental impact assessment studies.
Discussion
Mar - 23 2 Week 5 Deterioration of materials–paper, textiles, painted surfaces, prevention of microbial deterioration.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403: FOOD MICROBIOLOGY & AGRICULTURAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Microbiology of foods–Microbial flora of fresh foods, grains, fruits, vegetables, milk, meat,eggs and fish and their in festation by bacteria,fungi and viruses.
Seminar
4 Week 8 Microbiological examination of foods-microscopic techniques and cultural techniques.Direct microscopic examination, total colony counts and differential enumeration.
Discussion
Dec - 24
1 Week 6 Identification of specific groups–Bacteria, Viruses, Fungi and Protozoa. Interactive method
2 Week 5 Microbial spoilage of milk, food, types of spoilage organisms, food poisoning. Myco toxins and bacterial toxins.
Assignments given
3 Week 6 Food processing & preservation. Seminar
4 Week 7 Microorganisms as food–single cell protein, yeast, algae and fungal biomass production.
Discussion
Jan - 17
1 Week 5 Soil micobiology. Soil structure, soil profile, Physico-chemical conditions, Microbial composition.
Interactive method
2 Week 1 Sampling techniques. Assignments given
3 Week 4 Role of Microorganisms in organicmatter decomposition. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403: FOOD MICROBIOLOGY & AGRICULTURAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 7 Bio-geo chemical cycles–Carbon cycle, Nitrogen cycle–Nitrogen fixation. Nitrification, de-nitrification, sulpher, iron and phosphorus cycles. Seminar
Feb - 23
1 Week 6 Rhizosphere–Rhizosphere Microorganisms, Biochelators (Siderophores).
Discussion
2 Week 5 Biofertilizers–Introduction, biofertilizers using nitrogen fixing microbes. Interactive method
3 Week 5 Phosphate solubilization-Rhizobium, Azato bacter, Azospirillum Assignments given
4 Week 7 Soil bactria-Anabaena Symbiosis. Seminar
1 Week 5
Blue green algae, Mycorrihiza, Biopesticides–toxins from Bacillus thuringiensis.
Discussion
Mar - 23 2 Week 5 Psuedomonas syringae, Biological Control–Use of Baculovirus, NPV virus, protozoa & fungi in biological control.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 404: PHARMACEUTICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Chemical disinfectants, antiseptics and preservatives. Seminar
4 Week 8 Antifungal antibiotics, Production of antibiotics–Penicillin, Streptomycin. Discussion
Dec - 24
1 Week 6 Erythromycin, bacitracin and tetracycline. Interactive method
2 Week 5 Mechanism of action of antibiotics–the bacterial cell wall, protein synthesis, chromosome function & replication. Assignments given
3 Week 6 Bacterial resistence to antibiotics –intrinsic & acquired resistence, biochemical mechanisam of resistance.
Seminar
4 Week 7 Assay of antibiotics–Penicillin, Streptomycin. Discussion
Jan - 17
1 Week 5 Industrial Production of Enzymes–amylases, Proteases. Interactive method
2 Week 1 Organic acids-lactic acid, citric acid. Assignments given
3 Week 4 Amino acids–L-lysine, L-glutamicacid; Food supplements and hormones. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2015-16
Department: P.G.MICROBIOLIGY Paper: MB: 404: PHARMACEUTICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: IV
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
4Week 7 Production of VitaminB12. Microbial transformation of sterioids & non sterioids. Seminar
Feb - 23
1 Week 6 Analytical Microbiology–microbiological assays of Vitamins (Riboflavin, B12). Discussion
2 Week 5 Microbiological assays of Aminoacids (lysine, tryptophan). Interactive method
3 Week 5 Ecology of Microorganisms as it effectsthe pharmaceutical industry. Assignments given
4 Week 7 Microbial spoilage &preservation of medicines using antimicrobial agents. Seminar
1 Week 5 Control of microbial risk in medicines.
Discussion
Mar - 23 2 Week 5 Contamination of non-sterile pharmaceuticals in hospital & community environments.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Class: MSC MICROBIOLOGY Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401 FERMENTATION TECHNOLOGY AND INDUSTRIAL MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 An introduction to fermentation processes – the range of fermentation processes. Seminar
4 Week 8 Microorganisms used in industrial microbiological processes – isolation,
preservation and strain improvement of industrially important microorganisms. Discussion
Dec - 24
1 Week 6 Screening methods, isolation of autotrophic mutants; Interactive method
2 Week 4 Media and materials required for industrial microbiological processes –
Antifoams. Assignments given
3 Week 6 Microbial growth kinetics, batch culture, continuous culture, fed batch culture
and Dual or multiple fermentations. Seminar
4 Week 8 Inoculum development for large-scale processes. Discussion
Jan - 19
1 Week 5 Design of fermenter- Construction and maintenance of aseptic conditions. Interactive method
2 Week 3 Control of various parameters.Sterilization of media. Assignments given
3 Week 3 Control of various parameters.Sterilization of media. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Class: MSC MICROBIOLOGY Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401 FERMENTATION TECHNOLOGY AND INDUSTRIAL MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Computer application in fermentation technology; Recovery and purification of
fermentation products; Fermentation Economics. Seminar
Feb - 20
1 Week 5 Production of ethyl alcohol, beer & wine. Discussion
2 Week 4 Enzyme probe biosensors, biochips, biofilms, bio surfactants, Biotransformation,
Petroleum Microbiology. Interactive method
3 Week 6 Microbial leaching- role of microorganisms in the recovery of minerals
(uranium, copper) from ores. Assignments given
4 Week 5 Microbial products from genetically modified (cloned) organisms ex: insulin; Seminar
Mar - 25
1 Week 6 Microbial groups involved in biogas production, design of digester. Discussion
2 Week 5
Patenting- Concept and its composition & protection of right and their
limitation, intellectual property rights (IPR); patenting biotechnology inventions.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 402 ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 Basic concepts of Ecology and Environment – Biological spectrum at levels of
organization & realm of ecology Seminar
4 Week 8 Ecosystem – Concept, components, food chains, food webs and tropic levels;
Energy transfer efficiencies between tropic levels. Discussion
Dec - 24
1 Week 6 Biological factors influencing the growth and survival of microorganisms- inter
reactions of microbial population and community dynamics – Growth in closed
environments and in open environments.
Interactive method
2 Week 4 The kinetic properties of competition between microbial populations; Kinetic
principles of preypredator relationship. Assignments given
3 Week 6 Aquatic environment- Fresh water microorganisms, their zonation and
characteristics- Salt water, oceans, estuaries. Seminar
4 Week 8 Microorganism their zonation and characteristics-Faecal pollution of waters –
water borne diseases. Discussion
Jan - 19
1 Week 5 Indicator organisms; IMVIC test, sanitary examination of water; Atmospheric
Environment- Dispersal of airborne microorganisms. Interactive method
2 Week 3 Air Sampling principles and techniques; Air spora- Concepts and components,
indoor and outdoor air spora; Diurnal periodicity patterns; Seasonal periodicity
patterns; Vertical profiles.
Assignments given
3 Week 3 Microorganisms and pollution- Microbial production of methyl mercury,
trimethyl arsine, hydrogen sulphide. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 402 ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Acid rain water, carbon monoxide, ammonia, nitrate, nitrogen
oxides.nitrosamines, Eutrophication, algal toxins. Seminar
Feb - 20
1 Week 5 Microorganisms and sewage treatment- COD, BOD & DO, trickling filters
activated sludge process. Discussion
2 Week 4 Oxidation ponds; sludge treatment. Interactive method
3 Week 6 Bioremediation Technology – Microbial degradation of oil spills, pesticides and
detergents, Biofoulin. Assignments given
4 Week 5 Fate of genetically engineered microorganisms in the environment. Seminar
Mar - 25
1 Week 6 Environmental impact assessment studies. Discussion
2 Week 5 Deterioration of materials – paper, textiles, painted surfaces, prevention of
microbial deterioration. Seminar
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403 FOOD AND AGRICULTURE MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 Microbiology of foods – Microbial flora of fresh foods, grains, fruits, vegetables,
milk, meat, eggs and fish and their infestation by bacteria, fungi and viruses. Seminar
4 Week 8 Microbiological examination of foods- microscopic techniques and cultural
techniques. Discussion
Dec - 24
1 Week 6 Direct microscopic examination, total colony counts and differential
enumeration. Interactive method
2 Week 4 Identification of specific groups – Bacteria, Viruses, Fungi and Protozoa. Assignments given
3 Week 6 Microbial spoilage of milk, food, types of spoilage organisms, food poisoning,
mycotoxins and bacterial toxins. Seminar
4 Week 8 Food processing & preservation- Methods of food preservation, Aseptic
handling, pasteurization of milk, refrigeration and freezing, dehydration, osmotic
pressure.
Discussion
Jan - 19
1 Week 5 Chemicals – organic acids, nitrates, nitrites and cresols; Radiation – UV light, Y-
irradiation. Interactive method
2 Week 3 Fermented foods – preparation of Yogurt, streptococcus species, Lactobacillus
bulgaricus. Assignments given
3 Week 3 Manufacture of cheese, Pencillium; Fermented soybean products. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403 FOOD AND AGRICULTURE MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Microorganisms as food – single cell protein, yeast, algae and fungal biomass
production. Seminar
Feb - 20
1 Week 5 Soil Environment- Microorganisms, soil structure, soil profile, Physico-chemical
conditions, Microbial composition, sampling techniques. Discussion
2 Week 4
Role of microorganisms in organic matter decomposition,Bio-geo chemical
cycles – Carbon cycle, Nitrogen cycle – Nitrogen fixation, nitrification,
denitrification, sulphur, iron and phosphorus cycles.
Interactive method
3 Week 6 Rhizosphere – Rhizosphere Microorganisms, Biochelators (Siderophores) Assignments given
4 Week 5 Biofertilizers – Introduction, biofertilizers using nitrogen fixing microbes –
phosphate solubilization- Rhizobium, Azatobacter, Azospirillum,Azolla Seminar
Mar - 25
1 Week 6 Anabaena Symbiosis, blue green algae, Mycorrihiza, Biopesticides – toxins from
Bacillus thuringiensis, Psuedomonassyringae. Discussion
2 Week 5 Biological Control – Use of Baculovirus, NPV virus, protozoa & fungi in
biological control. Seminar
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 404 BIOSTATISTICS AND RESEARCH METHODOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 Elements of Biostatistics: Introduction to Biostatistics; Methods of representation
of statistical data; Data - Data types, collection of data, classification and
tabulation, population and sample designs.
Seminar
4 Week 8 Random and Non- random sampling methods, Handling of bulky data-
construction a histogram- interpretation of histogram. Discussion
Dec - 24
1 Week 6 Measures of Central tendency and distribution – mean, median, mode, Measures
of variation - Range, quartile deviation, mean deviation and standard deviation. Interactive method
2 Week 4 Coefficient of variation; Concept of Probability-Basic principles of probability
theory, Bayes theorem. Assignments given
3 Week 6 Normal distribution, statistical inference – Addition and multiplication theories,
conditional probability and probability distributors; Binomial, poission and
normal distribution.
Seminar
4 Week 8 Statistical applications in biology- Experimental designs; measures of
dispersion- standard deviation, standard error; Concept of correlation and
linear regression.
Discussion
Jan - 19
1 Week 5 Regression coefficients and properties; Types of errors and levels of
significance. Interactive method
2 Week 3 Tests of significance- Comparison of variance (F-test), small sample test,
Student’s "t" test, Paired and unpaired t test, chi square test. Assignments given
3 Week 3 Analysis of variance (ANOVA) – one way and two way, multiple
comparisons; Introduction to hidden Markov models. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 404 BIOSTATISTICS AND RESEARCH METHODOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Basics of Research Methodology - Literature survey, origin and identification of
problem, Formulation hypothesis based on existing information, Validation of
hypothesis.
Seminar
Feb - 20
1 Week 5 Designing experimental techniques for validating the hypothesis, Execution of
designed experiments. Discussion
2 Week 4 Analysis of data, Interpretation of research findings, Preparation of PhD thesis,
Oral presentation. Interactive method
3 Week 6
Methodology for writing science report- Compilation of experimental record,
program of writing, use of vocabulary, art of illustration, technical report
writing, editing and correcting, and manuscript writing for publication in peer
reviewed scientific journals.
Assignments given
4 Week 5 Research Project submission and execution- Preparation of informal proposal,
modified proposal and formal proposal. Seminar
Mar - 25
1 Week 6
Experimental design and Collection of results, submission of progress report
(year wise) and submission of technical report (Format- Title page, Introduction,
Aims of the proposal/research, methodology, results, references,
acknowledgments, budgetary preparation).
Discussion
2 Week 5 Submission of final technical report, Patenting and intellectual property rights. Seminar
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 24
1 Week 5 DNA & RNA as genetic material; Transformation experiments, Blenders
experiments, properties of genetic material Seminar
2 Week 5 Modern concept of gene structure; Overlapping genes, split genes, constitutive
genes, jumping genes, Oncogenes. Discussion
3 Week 6 Types of tumors, physical, chemical and biological Carcinogens, chromosomal
changes induced by Carcinogens Interactive method
4 Week 8 DNA replication –various modes of replication, Meselson-Stahl’s studies on
replication. Assignments given
Aug - 22
1 Week 6 Enzymes and Proteins involved in replication Mechanism of replication –
Initiation, polymerization and termination. Seminar
2 Week 4 Topoisomerases, DNA ligases; Prokaryotic and Eukaryotic promoters. Discussion
3 Week 4 Mechanism of transcription and transcriptional activators; Posttranscriptional
modifications. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
4 Week 8 The genetic code- Deciphering the genetic code; theory of triplet code,
elucidation of base composition of codons. Seminar
Sept - 23
1 Week 5 Protein synthesis- Mechanism and role of various factors involved in Initiation,
elongation and termination of Protein Synthesis, Inhibitors of protein synthesis. Discussion
2 Week 4 Post translational processing of proteins, protein channelling, role of RNA in
protein synthesis. Interactive method
3 Week 6 Regulation of gene expression at the levels of transcription and translation;
Operon concept; Assignments given
4 Week 8 Regulatory genes, structural genes and repressors; Negative and Positive
regulation. Seminar
Oct- 18
1 Week 6 Regulation of lac, ara and trp operons; Catabolite repression; Regulation of
gene expression in lambda and nif operon. Discussion
2 Week 0
3 Week 5 Semester-end Examinations
4 Week 7
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17
Department: P.G.MICROBIOLIGY Paper: MB: 302 GENETIC ENGINEERING Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 24
1 Week 5 r-DNA technology- Isolation of nucleic acids, DNA sequencing, Maxam-
Gilbert and Dideoxy methods. Seminar
2 Week 5 Restriction endonucleases, restriction maps, Southern, Northern and western
blotting. Discussion
3 Week 6 DNA finger printing, PCR- principle, types, application. Interactive method
4 Week 8 Cloning vectors- Plasmids, Cosmids and bacteriophages; Ligases- DNA
ligases, ligation of fragments with cohesive ends & blunt ends. Assignments given
Aug - 22
1 Week 6 Homopolymer tailing, Cloning strategies – shot gun experiments, gene
libraries. Seminar
2 Week 4 Isolation of poly mRNA, synthesis of c-DNA, cloning of cDNA in bacteria. Discussion
3 Week 4 Isolation of cloned genes, identification of recombinants, structural and
functional analysis of recombinants. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17
Department: P.G.MICROBIOLIGY Paper: MB: 302 GENETIC ENGINEERING Class: MSC MICROBIOLOGY Semester: III
4 Week 8 Gene expression- expression of cloned genes in bacteria, yeast, plant and animal
cells. Seminar
Sept - 23
1 Week 5 Applications of recombinant DNA technology in biology, plant, medicine. Discussion
2 Week 4 Applications of recombinant DNA technology in genetic diseases, gene therapy. Interactive method
3 Week 6 Nucleic acid probe technology, DNA micro array – printing of oligonucleotides
and PCR products on glass slides, nitrocellulose paper. Assignments given
4 Week 8 Whole genome analysis for global patterns of gene expression using fluorescent-
labeled c-DNA or end labeled RNA probes. Seminar
Oct- 18
1 Week 6 Analysis of single nucleotide polymorphisms using DNA chips; Protein micro
array, advantages and disadvantages of DNA and protein micro arrays. Discussion
2 Week 0
3 Week 5 Semester-end Examinations
4 Week 7
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Class: MSC MICROBIOLOGY
Department: P.G.MICROBIOLIGY Paper: MB: 303 BIOINFORMATICS, MICROBIAL GENOMICS AND PROTEOMICS Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 24
1 Week 5 Introduction to Biological Databases - Types of databases, Nucleic Acid
Sequence databases, Protein sequence database. Seminar
2 Week 5 Genomics, Transcriptomics, Proteomics and Metabolomics. Discussion
3 Week 6 . Bioinformatics and its applications - Structure-function relationship;
Sequence assembling using computer. Interactive method
4 Week 8 Computer applications in molecular biology, Protein domains and human
genome analysis program (BLAST, FASTA, GCC etc.). Assignments given
Aug - 22
1 Week 6 Databases for nucleic acid and protein sequences (EMBL, GenBank), database
for protein structure (PDB), accessing information (Network expasy, EMB
Net, ICGEB Net).
Seminar
2 Week 4 Proteomics - Proteome, metaproteome, structural proteomics, functional
proteomics; Protein structure analysis, sequence based protein
prediction.
Discussion
3 Week 4 Homology or comparative modeling- Remote homology (Threading),
Protein function prediction- Introduction to the concepts of molecular
modeling.
Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17 Class: MSC MICROBIOLOGY
Department: P.G.MICROBIOLIGY Paper: MB: 303 BIOINFORMATICS, MICROBIAL GENOMICS AND PROTEOMICS Semester: III
4 Week 8 Drug discovery, Structure based drug designing and virtual screening by
automated docking. De novo sequence; Molecular docking, evaluation of
docking prediction.
Seminar
Sept - 23
1 Week 5 Genomics - Whole genome analysis-Preparation of ordered cosmid
libraries, bacterial artificial chromosomal libraries, shotgun libraries and
sequencing, conventional sequencing, automated sequencing.
Discussion
2 Week 4 . Sequence analysis Computational methods, homology algorithm for
proteins and nucleic acids, open reading frames, annotations of genes,
conserved protein motifs related structure / function.
Interactive method
3 Week 6 DNA analyses for repeats (Direct and inverted), palindromes, folding
programmes; Benefits of Pharmacogenomics. Assignments given
4 Week 8 Integration of omic approaches - Application of omic technologies in
bioprospecting, biodegradation and medicine; Systems approaches using high
through put technologies for biomining microorganisms.
Seminar
Oct- 18
1 Week 6 Strategies for the analysis of bacterial biodegradation path ways, Concept of
Laboratory-on-a-chip (LOC); Omic tools. Discussion
2 Week 0
3 Week 5 Semester-end Examinations
4 Week 7
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17
Department: P.G.MICROBIOLIGY Paper: MB: 304 MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 24
1 Week 5 Normal microbial flora of human body, host-microbe interactions; Infection
and infection process- routes of transmission of microbes in the body. Seminar
2 Week 5 Description and pathology of diseases caused by bacteria; Streptococcus,
Pneumococcus, Gonococcus, Enterobacteriaceae, E. coli, Salmonella. Discussion
3 Week 6 Shigella, Pseudomonas, Klebsiella, Proteus, Vibrio cholera; Brucella,
Haemophilus, influenzae. Interactive method
4 Week 8 Pathogenic anaerobes, Tetanus, Clostridia, Corynebacteria, Mycobacteria,
Spirochaetes. Assignments given
Aug - 22
1 Week 6 Description and pathology of diseases caused by Aspergillus, Penicillium,
Mucomycosis, Blastomycosis, Microsporosis, Rhinosporidium,
Epidermophyscosis. Seminar
2 Week 4 Description and pathology of diseases caused by hemoflagellates;
Leishmaniadonavani, L.tropica, Trypanosoma gambiense. Intestinal flagellates Discussion
3 Week 4 Trichomonas, Giardia, Entamoeba histolytica, malarial parasites, Helminthes;
Ascaris lumbricoides, Hook worm, pinworm, Filarial parasites. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2016-17
Department: P.G.MICROBIOLIGY Paper: MB: 304 MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
4 Week 8 Laboratory diagnosis of Common infective syndromes and parasitic
manifestations; Methods of transmission and role of vectors- biology of vectors. Seminar
Sept - 23
1 Week 5 Need and significance of epidemiological studies; Epidemiological
investigations to identify a disease, Principles of chemotherapy. Discussion
2 Week 4 Mode of antibiotics - Penicillin, streptomycin, sulfonamides and Polymyxins. Interactive method
3 Week 6 Antifungal drugs (Nystatin), Antiviral agents (Robovirin); Problems of drug
resistance and drug sensitivity; Drug resistance in bacteria. Assignments given
4 Week 8 Viral diseases- Description, pathology and lab diagnosis of diseases
caused by poxviruses; herpes virus .orthomyxo and paramyxo viruses,
adenovirus.
Seminar
Oct- 18
1 Week 6 Otherrespiratory viruses, viruses affecting nervous system, enterovirus,
reovirus, viral hepatitis, HIV; Interferon – Nomenclature, types
&classification, Induction of interferon, types of inducers.
Discussion
2 Week 0
3 Week 5 Semester-end Examinations
4 Week 7
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Class: MSC MICROBIOLOGY Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401 FERMENTATION TECHNOLOGY AND INDUSTRIAL MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 An introduction to fermentation processes – the range of fermentation processes. Seminar
4 Week 8 Microorganisms used in industrial microbiological processes – isolation,
preservation and strain improvement of industrially important microorganisms. Discussion
Dec - 23
1 Week 5 Screening methods, isolation of autotrophic mutants; Interactive method
2 Week 5 Media and materials required for industrial microbiological processes –
Antifoams. Assignments given
3 Week 6 Microbial growth kinetics, batch culture, continuous culture, fed batch culture
and Dual or multiple fermentations. Seminar
4 Week 7 Inoculum development for large-scale processes. Discussion
Jan - 17
1 Week 5 Design of fermenter- Construction and maintenance of aseptic conditions. Interactive method
2 Week 3 Control of various parameters.Sterilization of media. Assignments given
3 Week 3 Control of various parameters.Sterilization of media. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Class: MSC MICROBIOLOGY Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401 FERMENTATION TECHNOLOGY AND INDUSTRIAL MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 6 Computer application in fermentation technology; Recovery and purification of
fermentation products; Fermentation Economics. Seminar
Feb - 22
1 Week 6 Production of ethyl alcohol, beer & wine. Discussion
2 Week 4 Enzyme probe biosensors, biochips, biofilms, bio surfactants, Biotransformation,
Petroleum Microbiology. Interactive method
3 Week 6 Microbial leaching- role of microorganisms in the recovery of minerals
(uranium, copper) from ores. Assignments given
4 Week 6 Microbial products from genetically modified (cloned) organisms ex: insulin; Seminar
Mar - 23
1 Week 5 Microbial groups involved in biogas production, design of digester. Discussion
2 Week 5
Patenting- Concept and its composition & protection of right and their
limitation, intellectual property rights (IPR); patenting biotechnology inventions.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 402 ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 Basic concepts of Ecology and Environment – Biological spectrum at levels of
organization & realm of ecology Seminar
4 Week 8 Ecosystem – Concept, components, food chains, food webs and tropic levels;
Energy transfer efficiencies between tropic levels. Discussion
Dec - 23
1 Week 5 Biological factors influencing the growth and survival of microorganisms- inter
reactions of microbial population and community dynamics – Growth in closed
environments and in open environments.
Interactive method
2 Week 5 The kinetic properties of competition between microbial populations; Kinetic
principles of preypredator relationship. Assignments given
3 Week 6 Aquatic environment- Fresh water microorganisms, their zonation and
characteristics- Salt water, oceans, estuaries. Seminar
4 Week 7 Microorganism their zonation and characteristics-Faecal pollution of waters –
water borne diseases. Discussion
Jan - 17
1 Week 5 Indicator organisms; IMVIC test, sanitary examination of water; Atmospheric
Environment- Dispersal of airborne microorganisms. Interactive method
2 Week 3 Air Sampling principles and techniques; Air spora- Concepts and components,
indoor and outdoor air spora; Diurnal periodicity patterns; Seasonal periodicity
patterns; Vertical profiles.
Assignments given
3 Week 3 Microorganisms and pollution- Microbial production of methyl mercury,
trimethyl arsine, hydrogen sulphide. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 402 ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 6 Acid rain water, carbon monoxide, ammonia, nitrate, nitrogen
oxides.nitrosamines, Eutrophication, algal toxins. Seminar
Feb - 22
1 Week 6 Microorganisms and sewage treatment- COD, BOD & DO, trickling filters
activated sludge process. Discussion
2 Week 4 Oxidation ponds; sludge treatment. Interactive method
3 Week 6 Bioremediation Technology – Microbial degradation of oil spills, pesticides and
detergents, Biofoulin. Assignments given
4 Week 6 Fate of genetically engineered microorganisms in the environment. Seminar
Mar - 23
1 Week 5 Environmental impact assessment studies. Discussion
2 Week 5 Deterioration of materials – paper, textiles, painted surfaces, prevention of
microbial deterioration. Seminar
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403 FOOD AND AGRICULTURE MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 Microbiology of foods – Microbial flora of fresh foods, grains, fruits, vegetables,
milk, meat, eggs and fish and their infestation by bacteria, fungi and viruses. Seminar
4 Week 8 Microbiological examination of foods- microscopic techniques and cultural
techniques. Discussion
Dec - 23
1 Week 5 Direct microscopic examination, total colony counts and differential
enumeration. Interactive method
2 Week 5 Identification of specific groups – Bacteria, Viruses, Fungi and Protozoa. Assignments given
3 Week 6 Microbial spoilage of milk, food, types of spoilage organisms, food poisoning,
mycotoxins and bacterial toxins. Seminar
4 Week 7 Food processing & preservation- Methods of food preservation, Aseptic
handling, pasteurization of milk, refrigeration and freezing, dehydration, osmotic
pressure.
Discussion
Jan - 17
1 Week 5 Chemicals – organic acids, nitrates, nitrites and cresols; Radiation – UV light, Y-
irradiation. Interactive method
2 Week 3 Fermented foods – preparation of Yogurt, streptococcus species, Lactobacillus
bulgaricus. Assignments given
3 Week 3 Manufacture of cheese, Pencillium; Fermented soybean products. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403 FOOD AND AGRICULTURE MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 6 Microorganisms as food – single cell protein, yeast, algae and fungal biomass
production. Seminar
Feb - 22
1 Week 6 Soil Environment- Microorganisms, soil structure, soil profile, Physico-chemical
conditions, Microbial composition, sampling techniques. Discussion
2 Week 4
Role of microorganisms in organic matter decomposition,Bio-geo chemical
cycles – Carbon cycle, Nitrogen cycle – Nitrogen fixation, nitrification,
denitrification, sulphur, iron and phosphorus cycles.
Interactive method
3 Week 6 Rhizosphere – Rhizosphere Microorganisms, Biochelators (Siderophores) Assignments given
4 Week 6 Biofertilizers – Introduction, biofertilizers using nitrogen fixing microbes –
phosphate solubilization- Rhizobium, Azatobacter, Azospirillum,Azolla Seminar
Mar - 23
1 Week 5 Anabaena Symbiosis, blue green algae, Mycorrihiza, Biopesticides – toxins from
Bacillus thuringiensis, Psuedomonassyringae. Discussion
2 Week 5 Biological Control – Use of Baculovirus, NPV virus, protozoa & fungi in
biological control. Seminar
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 404 BIOSTATISTICS AND RESEARCH METHODOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 14
3 Week 6 Elements of Biostatistics: Introduction to Biostatistics; Methods of representation
of statistical data; Data - Data types, collection of data, classification and
tabulation, population and sample designs.
Seminar
4 Week 8 Random and Non- random sampling methods, Handling of bulky data-
construction a histogram- interpretation of histogram. Discussion
Dec - 23
1 Week 5 Measures of Central tendency and distribution – mean, median, mode, Measures
of variation - Range, quartile deviation, mean deviation and standard deviation. Interactive method
2 Week 5 Coefficient of variation; Concept of Probability-Basic principles of probability
theory, Bayes theorem. Assignments given
3 Week 6 Normal distribution, statistical inference – Addition and multiplication theories,
conditional probability and probability distributors; Binomial, poission and
normal distribution.
Seminar
4 Week 7 Statistical applications in biology- Experimental designs; measures of
dispersion- standard deviation, standard error; Concept of correlation and
linear regression.
Discussion
Jan - 17
1 Week 5 Regression coefficients and properties; Types of errors and levels of
significance. Interactive method
2 Week 3 Tests of significance- Comparison of variance (F-test), small sample test,
Student’s "t" test, Paired and unpaired t test, chi square test. Assignments given
3 Week 3 Analysis of variance (ANOVA) – one way and two way, multiple
comparisons; Introduction to hidden Markov models. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 404 BIOSTATISTICS AND RESEARCH METHODOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 6 Basics of Research Methodology - Literature survey, origin and identification of
problem, Formulation hypothesis based on existing information, Validation of
hypothesis.
Seminar
Feb - 22
1 Week 6 Designing experimental techniques for validating the hypothesis, Execution of
designed experiments. Discussion
2 Week 4 Analysis of data, Interpretation of research findings, Preparation of PhD thesis,
Oral presentation. Interactive method
3 Week 6
Methodology for writing science report- Compilation of experimental record,
program of writing, use of vocabulary, art of illustration, technical report
writing, editing and correcting, and manuscript writing for publication in peer
reviewed scientific journals.
Assignments given
4 Week 6 Research Project submission and execution- Preparation of informal proposal,
modified proposal and formal proposal. Seminar
Mar - 23
1 Week 5
Experimental design and Collection of results, submission of progress report
(year wise) and submission of technical report (Format- Title page, Introduction,
Aims of the proposal/research, methodology, results, references,
acknowledgments, budgetary preparation).
Discussion
2 Week 5 Submission of final technical report, Patenting and intellectual property rights. Seminar
3 Week 6 Semester-end Examinations
4 Week 7
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 DNA & RNA as genetic material; Transformation experiments, Blenders
experiments, properties of genetic material Seminar
2 Week 5 Modern concept of gene structure; Overlapping genes, split genes, constitutive
genes, jumping genes, Oncogenes. Discussion
3 Week 6 Types of tumors, physical, chemical and biological Carcinogens, chromosomal
changes induced by Carcinogens Interactive method
4 Week 8 DNA replication –various modes of replication, Meselson-Stahl’s studies on
replication. Assignments given
Aug - 21
1 Week 4 Enzymes and Proteins involved in replication Mechanism of replication –
Initiation, polymerization and termination. Seminar
2 Week 4 Topoisomerases, DNA ligases; Prokaryotic and Eukaryotic promoters. Discussion
3 Week 5 Mechanism of transcription and transcriptional activators; Posttranscriptional
modifications. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
4 Week 8 The genetic code- Deciphering the genetic code; theory of triplet code,
elucidation of base composition of codons. Seminar
Sept - 18
1 Week 5 Protein synthesis- Mechanism and role of various factors involved in Initiation,
elongation and termination of Protein Synthesis, Inhibitors of protein synthesis. Discussion
2 Week 5 Post translational processing of proteins, protein channelling, role of RNA in
protein synthesis. Interactive method
3 Week 6 Regulation of gene expression at the levels of transcription and translation;
Operon concept; Assignments given
4 Week 2 Regulatory genes, structural genes and repressors; Negative and Positive
regulation. Seminar
Oct- 22
1 Week 5 Regulation of lac, ara and trp operons; Catabolite repression; Discussion
2 Week 5 Regulation of gene expression in lambda and nif operon.. Assignments given
3 Week 4 Semester-end Examinations
4 Week 8
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18
Department: P.G.MICROBIOLIGY Paper: MB: 302 GENETIC ENGINEERING Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 r-DNA technology- Isolation of nucleic acids, DNA sequencing, Maxam-
Gilbert and Dideoxy methods. Seminar
2 Week 5 Restriction endonucleases, restriction maps, Southern, Northern and western
blotting. Discussion
3 Week 6 DNA finger printing, PCR- principle, types, application. Interactive method
4 Week 8 Cloning vectors- Plasmids, Cosmids and bacteriophages; Ligases- DNA
ligases, ligation of fragments with cohesive ends & blunt ends. Assignments given
Aug - 21
1 Week 4 Homopolymer tailing, Cloning strategies – shot gun experiments, gene
libraries. Seminar
2 Week 4 Isolation of poly mRNA, synthesis of c-DNA, cloning of cDNA in bacteria. Discussion
3 Week 5 Isolation of cloned genes, identification of recombinants, structural and
functional analysis of recombinants. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18
Department: P.G.MICROBIOLIGY Paper: MB: 302 GENETIC ENGINEERING Class: MSC MICROBIOLOGY Semester: III
4 Week 8 Gene expression- expression of cloned genes in bacteria, yeast, plant and animal
cells. Seminar
Sept - 18
1 Week 5 Applications of recombinant DNA technology in biology, plant, medicine. Discussion
2 Week 5 Applications of recombinant DNA technology in genetic diseases, gene therapy. Interactive method
3 Week 6 Nucleic acid probe technology, DNA micro array – printing of oligonucleotides
and PCR products on glass slides, nitrocellulose paper. Assignments given
4 Week 2 Whole genome analysis for global patterns of gene expression using fluorescent-
labeled c-DNA or end labeled RNA probes. Seminar
Oct- 22
1 Week 5 Analysis of single nucleotide polymorphisms using DNA chips. Discussion
2 Week 5 Protein micro array, advantages and disadvantages of DNA and protein micro
arrays. Assignments given
3 Week 4 Semester-end Examinations
4 Week 8
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Class: MSC MICROBIOLOGY
Department: P.G.MICROBIOLIGY Paper: MB: 303 BIOINFORMATICS, MICROBIAL GENOMICS AND PROTEOMICS Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Introduction to Biological Databases - Types of databases, Nucleic Acid
Sequence databases, Protein sequence database. Seminar
2 Week 5 Genomics, Transcriptomics, Proteomics and Metabolomics. Discussion
3 Week 6 . Bioinformatics and its applications - Structure-function relationship;
Sequence assembling using computer. Interactive method
4 Week 8 Computer applications in molecular biology, Protein domains and human
genome analysis program (BLAST, FASTA, GCC etc.). Assignments given
Aug - 21
1 Week 4 Databases for nucleic acid and protein sequences (EMBL, GenBank), database
for protein structure (PDB), accessing information (Network expasy, EMB
Net, ICGEB Net).
Seminar
2 Week 4 Proteomics - Proteome, metaproteome, structural proteomics, functional
proteomics; Protein structure analysis, sequence based protein
prediction.
Discussion
3 Week 5 Homology or comparative modeling- Remote homology (Threading),
Protein function prediction- Introduction to the concepts of molecular
modeling.
Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18 Class: MSC MICROBIOLOGY
Department: P.G.MICROBIOLIGY Paper: MB: 303 BIOINFORMATICS, MICROBIAL GENOMICS AND PROTEOMICS Semester: III
4 Week 8 Drug discovery, Structure based drug designing and virtual screening by
automated docking. De novo sequence; Molecular docking, evaluation of
docking prediction.
Seminar
Sept - 18
1 Week 5 Genomics - Whole genome analysis-Preparation of ordered cosmid
libraries, bacterial artificial chromosomal libraries, shotgun libraries and
sequencing, conventional sequencing, automated sequencing.
Discussion
2 Week 5 . Sequence analysis Computational methods, homology algorithm for
proteins and nucleic acids, open reading frames, annotations of genes,
conserved protein motifs related structure / function.
Interactive method
3 Week 6 DNA analyses for repeats (Direct and inverted), palindromes, folding
programmes; Benefits of Pharmacogenomics. Assignments given
4 Week 2 Integration of omic approaches - Application of omic technologies in
bioprospecting, biodegradation and medicine. Seminar
Oct- 22
1 Week 5 Systems approaches using high through put technologies for biomining
microorganisms Discussion
2 Week 5 Strategies for the analysis of bacterial biodegradation path ways, Concept of
Laboratory-on-a-chip (LOC); Omic tools.
3 Week 4 Semester-end Examinations
4 Week 8
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18
Department: P.G.MICROBIOLIGY Paper: MB: 304 MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Normal microbial flora of human body, host-microbe interactions; Infection
and infection process- routes of transmission of microbes in the body. Seminar
2 Week 5 Description and pathology of diseases caused by bacteria; Streptococcus,
Pneumococcus, Gonococcus, Enterobacteriaceae, E. coli, Salmonella. Discussion
3 Week 6 Shigella, Pseudomonas, Klebsiella, Proteus, Vibrio cholera; Brucella,
Haemophilus, influenzae. Interactive method
4 Week 8 Pathogenic anaerobes, Tetanus, Clostridia, Corynebacteria, Mycobacteria,
Spirochaetes. Assignments given
Aug - 21
1 Week 4 Description and pathology of diseases caused by Aspergillus, Penicillium,
Mucomycosis, Blastomycosis, Microsporosis, Rhinosporidium,
Epidermophyscosis. Seminar
2 Week 4 Description and pathology of diseases caused by hemoflagellates;
Leishmaniadonavani, L.tropica, Trypanosoma gambiense. Intestinal flagellates Discussion
3 Week 5 Trichomonas, Giardia, Entamoeba histolytica, malarial parasites, Helminthes;
Ascaris lumbricoides, Hook worm, pinworm, Filarial parasites. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2017-18
Department: P.G.MICROBIOLIGY Paper: MB: 304 MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
4 Week 8 Laboratory diagnosis of Common infective syndromes and parasitic
manifestations; Methods of transmission and role of vectors- biology of vectors. Seminar
Sept - 18
1 Week 5 Need and significance of epidemiological studies; Epidemiological
investigations to identify a disease, Principles of chemotherapy. Discussion
2 Week 5 Mode of antibiotics - Penicillin, streptomycin, sulfonamides and Polymyxins. Interactive method
3 Week 6 Antifungal drugs (Nystatin), Antiviral agents (Robovirin); Problems of drug
resistance and drug sensitivity; Drug resistance in bacteria. Assignments given
4 Week 2 Viral diseases- Description, pathology and lab diagnosis of diseases
caused by poxviruses; herpes virus .orthomyxo and paramyxo viruses,
adenovirus.
Seminar
Oct- 22
1 Week 5 Otherrespiratory viruses, viruses affecting nervous system, enterovirus,
reovirus, viral hepatitis. Discussion
2 Week 5 Interferon – Nomenclature, types &classification, Induction of interferon,
types of inducers.
3 Week 4 Semester-end Examinations
4 Week 8
Nov- 11 1 Week 6
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Class: MSC MICROBIOLOGY Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401 FERMENTATION TECHNOLOGY AND INDUSTRIAL MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 An introduction to fermentation processes – the range of fermentation processes. Seminar
4 Week 8 Microorganisms used in industrial microbiological processes – isolation,
preservation and strain improvement of industrially important microorganisms. Discussion
Dec - 23
1 Week 6 Screening methods, isolation of autotrophic mutants; Interactive method
2 Week 6 Media and materials required for industrial microbiological processes –
Antifoams. Assignments given
3 Week 5 Microbial growth kinetics, batch culture, continuous culture, fed batch culture
and Dual or multiple fermentations. Seminar
4 Week 6 Inoculum development for large-scale processes. Discussion
Jan - 18
1 Week 5 Design of fermenter- Construction and maintenance of aseptic conditions. Interactive method
2 Week 4 Control of various parameters.Sterilization of media. Assignments given
3 Week 1 Control of various parameters.Sterilization of media. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Class: MSC MICROBIOLOGY Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 401 FERMENTATION TECHNOLOGY AND INDUSTRIAL MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Computer application in fermentation technology; Recovery and purification of
fermentation products; Fermentation Economics. Seminar
Feb - 21
1 Week 6 Production of ethyl alcohol, beer & wine. Discussion
2 Week 4 Enzyme probe biosensors, biochips, biofilms, bio surfactants, Biotransformation,
Petroleum Microbiology. Interactive method
3 Week 5 Microbial leaching- role of microorganisms in the recovery of minerals
(uranium, copper) from ores. Assignments given
4 Week 6 Microbial products from genetically modified (cloned) organisms ex: insulin; Seminar
Mar - 24
1 Week 5 Microbial groups involved in biogas production, design of digester. Discussion
2 Week 5
Patenting- Concept and its composition & protection of right and their
limitation, intellectual property rights (IPR); patenting biotechnology inventions.
Interactive method
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 402 ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Basic concepts of Ecology and Environment – Biological spectrum at levels of
organization & realm of ecology Seminar
4 Week 8 Ecosystem – Concept, components, food chains, food webs and tropic levels;
Energy transfer efficiencies between tropic levels. Discussion
Dec - 23
1 Week 6 Biological factors influencing the growth and survival of microorganisms- inter
reactions of microbial population and community dynamics – Growth in closed
environments and in open environments.
Interactive method
2 Week 6 The kinetic properties of competition between microbial populations; Kinetic
principles of preypredator relationship. Assignments given
3 Week 5 Aquatic environment- Fresh water microorganisms, their zonation and
characteristics- Salt water, oceans, estuaries. Seminar
4 Week 6 Microorganism their zonation and characteristics-Faecal pollution of waters –
water borne diseases. Discussion
Jan - 18
1 Week 5 Indicator organisms; IMVIC test, sanitary examination of water; Atmospheric
Environment- Dispersal of airborne microorganisms. Interactive method
2 Week 4 Air Sampling principles and techniques; Air spora- Concepts and components,
indoor and outdoor air spora; Diurnal periodicity patterns; Seasonal periodicity
patterns; Vertical profiles.
Assignments given
3 Week 1 Microorganisms and pollution- Microbial production of methyl mercury,
trimethyl arsine, hydrogen sulphide. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 402 ENVIRONMENTAL MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Acid rain water, carbon monoxide, ammonia, nitrate, nitrogen
oxides.nitrosamines, Eutrophication, algal toxins. Seminar
Feb - 21
1 Week 6 Microorganisms and sewage treatment- COD, BOD & DO, trickling filters
activated sludge process. Discussion
2 Week 4 Oxidation ponds; sludge treatment. Interactive method
3 Week 5 Bioremediation Technology – Microbial degradation of oil spills, pesticides and
detergents, Biofoulin. Assignments given
4 Week 6 Fate of genetically engineered microorganisms in the environment. Seminar
Mar - 24
1 Week 5 Environmental impact assessment studies. Discussion
2 Week 5 Deterioration of materials – paper, textiles, painted surfaces, prevention of
microbial deterioration. Seminar
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403 FOOD AND AGRICULTURE MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Microbiology of foods – Microbial flora of fresh foods, grains, fruits, vegetables,
milk, meat, eggs and fish and their infestation by bacteria, fungi and viruses. Seminar
4 Week 8 Microbiological examination of foods- microscopic techniques and cultural
techniques. Discussion
Dec - 23
1 Week 6 Direct microscopic examination, total colony counts and differential
enumeration. Interactive method
2 Week 6 Identification of specific groups – Bacteria, Viruses, Fungi and Protozoa. Assignments given
3 Week 5 Microbial spoilage of milk, food, types of spoilage organisms, food poisoning,
mycotoxins and bacterial toxins. Seminar
4 Week 6 Food processing & preservation- Methods of food preservation, Aseptic
handling, pasteurization of milk, refrigeration and freezing, dehydration, osmotic
pressure.
Discussion
Jan - 18
1 Week 5 Chemicals – organic acids, nitrates, nitrites and cresols; Radiation – UV light, Y-
irradiation. Interactive method
2 Week 4 Fermented foods – preparation of Yogurt, streptococcus species, Lactobacillus
bulgaricus. Assignments given
3 Week 1 Manufacture of cheese, Pencillium; Fermented soybean products. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 403 FOOD AND AGRICULTURE MICROBIOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Microorganisms as food – single cell protein, yeast, algae and fungal biomass
production. Seminar
Feb - 21
1 Week 6 Soil Environment- Microorganisms, soil structure, soil profile, Physico-chemical
conditions, Microbial composition, sampling techniques. Discussion
2 Week 4
Role of microorganisms in organic matter decomposition,Bio-geo chemical
cycles – Carbon cycle, Nitrogen cycle – Nitrogen fixation, nitrification,
denitrification, sulphur, iron and phosphorus cycles.
Interactive method
3 Week 5 Rhizosphere – Rhizosphere Microorganisms, Biochelators (Siderophores) Assignments given
4 Week 6 Biofertilizers – Introduction, biofertilizers using nitrogen fixing microbes –
phosphate solubilization- Rhizobium, Azatobacter, Azospirillum,Azolla Seminar
Mar - 24
1 Week 5 Anabaena Symbiosis, blue green algae, Mycorrihiza, Biopesticides – toxins from
Bacillus thuringiensis, Psuedomonassyringae. Discussion
2 Week 5 Biological Control – Use of Baculovirus, NPV virus, protozoa & fungi in
biological control. Seminar
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 404 BIOSTATISTICS AND RESEARCH METHODOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
Nov - 13
3 Week 5 Elements of Biostatistics: Introduction to Biostatistics; Methods of representation
of statistical data; Data - Data types, collection of data, classification and
tabulation, population and sample designs.
Seminar
4 Week 8 Random and Non- random sampling methods, Handling of bulky data-
construction a histogram- interpretation of histogram. Discussion
Dec - 23
1 Week 6 Measures of Central tendency and distribution – mean, median, mode, Measures
of variation - Range, quartile deviation, mean deviation and standard deviation. Interactive method
2 Week 6 Coefficient of variation; Concept of Probability-Basic principles of probability
theory, Bayes theorem. Assignments given
3 Week 5 Normal distribution, statistical inference – Addition and multiplication theories,
conditional probability and probability distributors; Binomial, poission and
normal distribution.
Seminar
4 Week 6 Statistical applications in biology- Experimental designs; measures of
dispersion- standard deviation, standard error; Concept of correlation and
linear regression.
Discussion
Jan - 18
1 Week 5 Regression coefficients and properties; Types of errors and levels of
significance. Interactive method
2 Week 4 Tests of significance- Comparison of variance (F-test), small sample test,
Student’s "t" test, Paired and unpaired t test, chi square test. Assignments given
3 Week 1 Analysis of variance (ANOVA) – one way and two way, multiple
comparisons; Introduction to hidden Markov models. Seminar
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Semester: IV
Department: P.G.MICROBIOLIGY Paper: MB: 404 BIOSTATISTICS AND RESEARCH METHODOLOGY Class: MSC MICROBIOLOGY
Month &
No.of
Working Days
Week
No.of
Periods
Per week
Topics to be covered Co-Curricular Activity
4 Week 8 Basics of Research Methodology - Literature survey, origin and identification of
problem, Formulation hypothesis based on existing information, Validation of
hypothesis.
Seminar
Feb - 21
1 Week 6 Designing experimental techniques for validating the hypothesis, Execution of
designed experiments. Discussion
2 Week 4 Analysis of data, Interpretation of research findings, Preparation of PhD thesis,
Oral presentation. Interactive method
3 Week 5
Methodology for writing science report- Compilation of experimental record,
program of writing, use of vocabulary, art of illustration, technical report
writing, editing and correcting, and manuscript writing for publication in peer
reviewed scientific journals.
Assignments given
4 Week 6 Research Project submission and execution- Preparation of informal proposal,
modified proposal and formal proposal. Seminar
Mar - 24
1 Week 5
Experimental design and Collection of results, submission of progress report
(year wise) and submission of technical report (Format- Title page, Introduction,
Aims of the proposal/research, methodology, results, references,
acknowledgments, budgetary preparation).
Discussion
2 Week 5 Submission of final technical report, Patenting and intellectual property rights. Seminar
3 Week 6 Semester-end Examinations
4 Week 8
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 DNA & RNA as genetic material; Transformation experiments, Blenders
experiments, properties of genetic material Seminar
2 Week 5 Modern concept of gene structure; Overlapping genes, split genes, constitutive
genes, jumping genes, Oncogenes. Discussion
3 Week 6 Types of tumors, physical, chemical and biological Carcinogens, chromosomal
changes induced by Carcinogens Interactive method
4 Week 8 DNA replication –various modes of replication, Meselson-Stahl’s studies on
replication. Assignments given
Aug - 24
1 Week 6 Enzymes and Proteins involved in replication Mechanism of replication –
Initiation, polymerization and termination. Seminar
2 Week 5 Topoisomerases, DNA ligases; Prokaryotic and Eukaryotic promoters. Discussion
3 Week 6 Mechanism of transcription and transcriptional activators; Posttranscriptional
modifications. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19
Department: P.G.MICROBIOLIGY Paper: MB: 301: MOLECULAR MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
4 Week 7 The genetic code- Deciphering the genetic code; theory of triplet code,
elucidation of base composition of codons. Seminar
Sept - 21
1 Week 5 Protein synthesis- Mechanism and role of various factors involved in Initiation,
elongation and termination of Protein Synthesis, Inhibitors of protein synthesis. Discussion
2 Week 4 Post translational processing of proteins, protein channelling, role of RNA in
protein synthesis. Interactive method
3 Week 5 Regulation of gene expression at the levels of transcription and translation;
Operon concept; Assignments given
4 Week 7 Regulatory genes, structural genes and repressors; Negative and Positive
regulation. Seminar
Oct- 19
1 Week 5 Regulation of lac, ara and trp operons; Catabolite repression; Discussion
2 Week 5 Regulation of gene expression in lambda and nif operon.. Assignments given
3 Week 0 Semester-end Examinations
4 Week 9
Nov- 9 1 Week 4
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19
Department: P.G.MICROBIOLIGY Paper: MB: 302 GENETIC ENGINEERING Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 r-DNA technology- Isolation of nucleic acids, DNA sequencing, Maxam-
Gilbert and Dideoxy methods. Seminar
2 Week 5 Restriction endonucleases, restriction maps, Southern, Northern and western
blotting. Discussion
3 Week 6 DNA finger printing, PCR- principle, types, application. Interactive method
4 Week 8 Cloning vectors- Plasmids, Cosmids and bacteriophages; Ligases- DNA
ligases, ligation of fragments with cohesive ends & blunt ends. Assignments given
Aug - 24
1 Week 6 Homopolymer tailing, Cloning strategies – shot gun experiments, gene
libraries. Seminar
2 Week 5 Isolation of poly mRNA, synthesis of c-DNA, cloning of cDNA in bacteria. Discussion
3 Week 6 Isolation of cloned genes, identification of recombinants, structural and
functional analysis of recombinants. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19
Department: P.G.MICROBIOLIGY Paper: MB: 302 GENETIC ENGINEERING Class: MSC MICROBIOLOGY Semester: III
4 Week 7 Gene expression- expression of cloned genes in bacteria, yeast, plant and animal
cells. Seminar
Sept - 21
1 Week 5 Applications of recombinant DNA technology in biology, plant, medicine. Discussion
2 Week 4 Applications of recombinant DNA technology in genetic diseases, gene therapy. Interactive method
3 Week 5 Nucleic acid probe technology, DNA micro array – printing of oligonucleotides
and PCR products on glass slides, nitrocellulose paper. Assignments given
4 Week 7 Whole genome analysis for global patterns of gene expression using fluorescent-
labeled c-DNA or end labeled RNA probes. Seminar
Oct- 19
1 Week 5 Analysis of single nucleotide polymorphisms using DNA chips. Discussion
2 Week 5 Protein micro array, advantages and disadvantages of DNA and protein micro
arrays. Assignments given
3 Week 0 Semester-end Examinations
4 Week 9
Nov- 9 1 Week 4
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Class: MSC MICROBIOLOGY
Department: P.G.MICROBIOLIGY Paper: MB: 303 BIOINFORMATICS, MICROBIAL GENOMICS AND PROTEOMICS Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Introduction to Biological Databases - Types of databases, Nucleic Acid
Sequence databases, Protein sequence database. Seminar
2 Week 5 Genomics, Transcriptomics, Proteomics and Metabolomics. Discussion
3 Week 6 . Bioinformatics and its applications - Structure-function relationship;
Sequence assembling using computer. Interactive method
4 Week 8 Computer applications in molecular biology, Protein domains and human
genome analysis program (BLAST, FASTA, GCC etc.). Assignments given
Aug - 24
1 Week 6 Databases for nucleic acid and protein sequences (EMBL, GenBank), database
for protein structure (PDB), accessing information (Network expasy, EMB
Net, ICGEB Net).
Seminar
2 Week 5 Proteomics - Proteome, metaproteome, structural proteomics, functional
proteomics; Protein structure analysis, sequence based protein
prediction.
Discussion
3 Week 6 Homology or comparative modeling- Remote homology (Threading),
Protein function prediction- Introduction to the concepts of molecular
modeling.
Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19 Class: MSC MICROBIOLOGY
Department: P.G.MICROBIOLIGY Paper: MB: 303 BIOINFORMATICS, MICROBIAL GENOMICS AND PROTEOMICS Semester: III
4 Week 7 Drug discovery, Structure based drug designing and virtual screening by
automated docking. De novo sequence; Molecular docking, evaluation of
docking prediction.
Seminar
Sept - 21
1 Week 5 Genomics - Whole genome analysis-Preparation of ordered cosmid
libraries, bacterial artificial chromosomal libraries, shotgun libraries and
sequencing, conventional sequencing, automated sequencing.
Discussion
2 Week 4 . Sequence analysis Computational methods, homology algorithm for
proteins and nucleic acids, open reading frames, annotations of genes,
conserved protein motifs related structure / function.
Interactive method
3 Week 5 DNA analyses for repeats (Direct and inverted), palindromes, folding
programmes; Benefits of Pharmacogenomics. Assignments given
4 Week 7 Integration of omic approaches - Application of omic technologies in
bioprospecting, biodegradation and medicine. Seminar
Oct- 19
1 Week 5 Systems approaches using high through put technologies for biomining
microorganisms Discussion
2 Week 5 Strategies for the analysis of bacterial biodegradation path ways, Concept of
Laboratory-on-a-chip (LOC); Omic tools.
3 Week 0 Semester-end Examinations
4 Week 9
Nov- 9 1 Week 4
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19
Department: P.G.MICROBIOLIGY Paper: MB: 304 MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
Month &
No.of
Working Days
Week
No.of
Periods Per
week
Topics to be covered Co-Curricular Activity
June - 26
1 Week
2 Week
3 Week
4 Week
July - 25
1 Week 6 Normal microbial flora of human body, host-microbe interactions; Infection
and infection process- routes of transmission of microbes in the body. Seminar
2 Week 5 Description and pathology of diseases caused by bacteria; Streptococcus,
Pneumococcus, Gonococcus, Enterobacteriaceae, E. coli, Salmonella. Discussion
3 Week 6 Shigella, Pseudomonas, Klebsiella, Proteus, Vibrio cholera; Brucella,
Haemophilus, influenzae. Interactive method
4 Week 8 Pathogenic anaerobes, Tetanus, Clostridia, Corynebacteria, Mycobacteria,
Spirochaetes. Assignments given
Aug - 24
1 Week 6 Description and pathology of diseases caused by Aspergillus, Penicillium,
Mucomycosis, Blastomycosis, Microsporosis, Rhinosporidium,
Epidermophyscosis. Seminar
2 Week 5 Description and pathology of diseases caused by hemoflagellates;
Leishmaniadonavani, L.tropica, Trypanosoma gambiense. Intestinal flagellates Discussion
3 Week 6 Trichomonas, Giardia, Entamoeba histolytica, malarial parasites, Helminthes;
Ascaris lumbricoides, Hook worm, pinworm, Filarial parasites. Interactive method
Signature of the Lecturer Signature of the HOD Signature of the Principal
DANTULURI NARAYANA RAJU COLLEGE (AUTONOMOUS)
(A College with Potential for Excellence)
Bhimavaram, W.G.Dist, A.P
Annual Curricular Plan for the Academic Year 2018-19
Department: P.G.MICROBIOLIGY Paper: MB: 304 MEDICAL MICROBIOLOGY Class: MSC MICROBIOLOGY Semester: III
4 Week 7 Laboratory diagnosis of Common infective syndromes and parasitic
manifestations; Methods of transmission and role of vectors- biology of vectors. Seminar
Sept - 21
1 Week 5 Need and significance of epidemiological studies; Epidemiological
investigations to identify a disease, Principles of chemotherapy. Discussion
2 Week 4 Mode of antibiotics - Penicillin, streptomycin, sulfonamides and Polymyxins. Interactive method
3 Week 5 Antifungal drugs (Nystatin), Antiviral agents (Robovirin); Problems of drug
resistance and drug sensitivity; Drug resistance in bacteria. Assignments given
4 Week 7 Viral diseases- Description, pathology and lab diagnosis of diseases
caused by poxviruses; herpes virus .orthomyxo and paramyxo viruses,
adenovirus.
Seminar
Oct- 19
1 Week 5 Otherrespiratory viruses, viruses affecting nervous system, enterovirus,
reovirus, viral hepatitis. Discussion
2 Week 5 Interferon – Nomenclature, types &classification, Induction of interferon,
types of inducers.
3 Week 0 Semester-end Examinations
4 Week 9
Nov- 9 1 Week 4
Semester-end Examinations
2 Week 5
Signature of the Lecturer Signature of the HOD Signature of the Principal