December 4-6, 2011Omni Shoreham Hotel | Washington, D.C.

FACULTYN. Scott Adzick, MD Surgeon-in-ChiefChildren’s Hospital of PhiladelphiaC. Everett Koop Professor of Pediatric Surgery University of Pennsylvania School of MedicinePhiladelphia, PA

Dale C. Alverson, MD Professor of Pediatrics and Regents’ ProfessorProfessor, Health Sciences Center Library and Informatics CenterMedical Director, Center for Telehealth and Cybermedicine ResearchUniversity of New Mexico Health Sciences CenterAlbuquerque, NM

Eduardo Bancalari, MD Chief, Newborn ServiceJackson Memorial Hospital Professor of Pediatrics/Director, Division of Neonatology University of Miami Miller School of MedicineMiami, FL

Myriam Peralta Carcelen, MD, MPHDirector UAB Newborn Follow Up ClinicProfessor of PediatricsUniversity of Alabama at BirminghamBirmingham, AL

Charles Michael Cotten, MD, MHScDirector of Clinical Research Duke University Medical CenterAssociate Professor of PediatricsDuke University School of MedicineDurham, NC

Maureen Hack, MB ChBProfessor of Pediatrics Case Western Reserve UniversityCleveland, OH

Rosemary D. Higgins, MD Program Scientist Neonatal Research Network NICHDBethesda, MD

Terrie Inder, MB ChB, MDThe Division of Newborn MedicineSt. Louis Children’s HospitalProfessor in Pediatrics Washington University in St. LouisSt. Louis, MO

Sandra Juul, MD, PhDProfessor of Pediatrics University of Washington Seattle, WA

Paolo Manzoni, MDSenior Faculty StaffNeonatology and NICU St. Anna Hospital Torino, Italy

Mary Ellen McCann, MD, MPH Senior Associate in Anesthesiology Children’s Hospital Boston Assistant Professor of Anesthesiology Harvard Medical School Boston, MA

David W.A. Milligan, MD, FRCPCHConsultant NeonatologistRoyal Victoria Infirmary Honorary Clinical LecturerNewcastle University Newcastle, England

Helen Mintz-Hittner, MD Pediatric OphthalmologistChildren’s Memorial Hermann Hospital Professor in Ophthalmology and Visual ScienceUniversity of Texas Health Science Center at Houston-Medical School Houston, TX

Graham E. Quinn, MD, MSCEProfessor of OphthalmologyChildren’s Hospital of PhiladelphiaProfessor of Ophthalmology Scheie Eye InstituteUniversity of Pennsylvania Philadelphia, PA

Roberto Romero, MDChief, Perinatology Research Branch NICHDNational Institutes of Health Detroit, MI

Barbara Schmidt, MD Professor of Pediatrics and Kristine Sandberg Knisely Chair in NeonatologySenior Scholar, Center for Clinical Epidemiology & BiostatisticsUniversity of Pennsylvania, School of Medicine Philadelphia, PA

Seetha Shankaran, MD Director, Division of Neonatal/Perinatal MedicineChildren’s Hospital of Michigan and Hutzel Women’s HospitalProfessor of PediatricsWayne State University School of Medicine Detroit, MI

Atul Singhal, MD Honorary Consultant Pediatrician Great Ormond Street HospitalProfessor of Pediatric Nutrition UCL Institute of Child Health London, England

Gautham K. Suresh, MD, DM, MSAttending Physician, NeonatologistDartmouth-Hitchcock Medical CenterAssociate Professor of Pediatrics and Community and Family MedicineDartmouth Medical SchoolHanover, NH

Robert C. Tasker, MBBS, MD, FRCPChair and Director, Neurocritical CareChildren’s Hospital Boston Professor of Neurology and AnesthesiaHarvard Medical School Boston, MA

Marianne Thoresen, MD, PhDConsultant NeonatologistSt. Michael’s Hospital Professor of Neonatal NeuroscienceUniversity of Bristol Bristol, England

Yvonne E. Vaucher, MD, MPHFollow-Up PI NICHD Neonatal Research NetworkSUPPORT Trial Clinical Professor of Pediatrics-RetiredUniversity of California, San DiegoSan Diego, CA

Betty Vohr, MD Director, Neonatal Follow-Up Clinic Women and Infants Hospital Professor of Pediatrics Warren Alpert Medical School of Brown University Providence, RI

Ronald Wapner, MD Vice Chair of Research Columbia University Professor of OB/GYNColumbia University Medical Center/ NY Presbyterian Hospital New York, NY

Warren W. Wasiewski, MDChief Medical OfficerInfacare Pharmaceutical Corp. Trevose, PA

Mervin C. Yoder, MD Neonatology – Department of PediatricsRiley Hospital for Children and Community North Hospital Professor of Pediatrics and Director of the Herman B. Wells Center for Pediatric Research Indiana University School of Medicine Indianapolis, IN

MODERATORS

David Edwards, DSc, FMedSciWeston Professor of Neonatal MedicineDirector, Centre for the Developing Brain Imperial CollegeLondon, England

Avroy A. Fanaroff, MDEliza Henry Barnes Professor of NeonatologyRainbow Babies and Children's HospitalProfessor of PediatricsCWRU School of MedicineCleveland, Ohio

Jay S. Greenspan, MD, MBARobert L. Brent Professor and ChairmanDepartment of PediatricsNemours/Alfred I. duPont Hospital for Children/Thomas Jefferson UniversityWilmington, DE

Terrie Inder, MB ChB, MDThe Division of Newborn MedicineSt. Louis Children’s HospitalProfessor in Pediatrics Washington University in St. LouisSt. Louis, MO

Alan H. Jobe, MD, PhDDirector, Division of Perinatal Biology Cincinnati Children’s Hospital Medical CenterProfessor of Pediatrics University of Cincinnati

Cincinnati, OH M. Jeffrey Maisels, MD, DScPhysician-in-ChiefBeaumont Children’s HospitalProfessor and Chair Department of Pediatrics Oakland University William Beaumont School of Medicine Royal Oak, MI

Andrew R. Wilkinson, MB ChB, FRCP, FRCPCHProfessor of Paediatrics and Perinatal MedicineOxford UniversityNeonatal Unit, Women's CentreJohn Radcliffe HospitalOxford, England

PROGRAM DIRECTORSJay S. Greenspan, MD, MBARobert L. Brent Professor and ChairmanDepartment of PediatricsNemours/Alfred I. duPont Hospital for Children/Thomas Jefferson University

Jerold F. Lucey, MD, FAAPProfessor of Pediatrics, EmeritusWallace Professor of Neonatology, EmeritusUniversity of VermontEditor-in-Chief, Pediatrics, Emeritus

Sunday, December 42:00 – 6:00 p.m. Registration at West Registration Desk

6:00 – 7:00 p.m. Reception – Empire Room

Monday, December 5

7:00 a.m. Registration at West Registration Desk/ Continental Breakfast

7:45 a.m. Doors open

8:15 a.m. Welcome and Introductions Jerold F. Lucey, MD Jay S. Greenspan, MD, MBA

Current Interest Moderator Andrew R. Wilkinson, MB ChB, FRCP, FRCPCH8:30 a.m. Late Effects of Anesthesia in Infants* Mary Ellen McCann, MD, MPH

9:00 a.m. Prenatal Surgery for Spina Bifida- N. Scott Adzick, MDMOMS Trial*

9:30 a.m. Cord Blood Storage – Pro and Con* Mervin C. Yoder, MD

10:00 a.m. Coffee Break/Poster Viewing**

Green Apples! Promising but? Moderator M. Jeffrey Maisels, MD, DSc10:30 a.m. Neonatal Hyperbilirubinemia – Stanate®* Warren W. Wasiewski, MD

11:00 a.m. Cost-effectiveness of routine Gautham K. Suresh, MD, DM, MS bilirubin screening

11:10 a.m. Audience Questions and Comments M. Jeffrey Maisels, MD, DSc

11:30 a.m. Autologous Cord Blood Cells for HIE Charles Michael Cotten, MD, MHSC

Noon Lunch (on your own)/Poster Viewing**

PerinatologyModerator Jay S. Greenspan, MD, MBA

1:30 p.m. Antenatal Steroids: What has Happened Ronald Wapner, MDSince Liggins and Howie

2:00 p.m. The Role of Progesterone in the Roberto Romero, MD Prevention of Preterm Birth

2:30 p.m. Discussion & Audience Questions Roberto Romero, MDRonald Wapner, MD

3:00 p.m. Coffee Break/Poster Viewing**

The FutureModerator Terrie Inder, MB ChB, MD

3:30 p.m. Oxygenation Targets: Eduardo Bancalari, MD Can They be Achieved?*

4:00 p.m. What’s New in Imaging* Terrie Inder, MB ChB, MD

4:30 p.m. A Brave New World: Dale C. Alverson, MDTelemedicine and eHealth in Neonatology*

5:00 p.m. Adjourn

5:30 – 6:30 p.m. Reception in the Empire Room – Meet a Robot!

Tuesday, December 6

7:00 a.m. Registration at West Registration Desk/ Continental Breakfast

7:30 a.m. Doors open

Current Interest Moderator Alan H. Jobe, MD, PhD8:00 a.m. Bevacizumab – Treatment for ROP Helen Mintz-Hittner, MD

8:20 a.m. Point-Counterpoint Graham E. Quinn, MD, MSCE Helen Mintz-Hittner, MD

8:30 a.m. Audience Questions (time permitting)

8:35 a.m. Follow-up – Seetha Shankaran, MD 7 Years of Brain Cooling NICHD Trial*

9:05 a.m. Long Term Follow-up: Creative Panel Discussion:Measures to Ensure Maximal Return Maureen Hack, MB ChB

Rosemary D. Higgins, MDSeetha Shankaran, MDBetty Vohr, MD

9:30 a.m. Getting the Most Out of David W. A. Milligan, MD, FRCPCHFollow-up Programmes*

10:00 a.m. Coffee Break/Poster Viewing **

Brain Cooling Plus What?Moderator David Edwards, DSc, FMedSci

10:30 a.m. Update on EPO Neuroprotection – Sandra Juul, MD, PhDHas its Time Come?*

11:00 a.m. Review of Adult Brain Cooling* Robert C. Tasker, MBBS, MD, FRCP

11:30 a.m. Brain Cooling and Xenon Marianne Thoresen, MD, PhD

11:50 a.m. Panel Discussion – Current Thoughts Panel Discussion:on the Future of Brain Cooling Plus David Edwards, DSc, FMedSciOther Possible Therapies Terrie Inder, MB ChB, MD

Marianne Thoresen, MD, PhD12:30 p.m. Lunch (on your own)/Poster Viewing**

NutritionModerator Avroy A. Fanaroff, MD

1:30 p.m. Early Nutrition and Atul Singhal, MDLong-term Risk of Obesity*

2:00 p.m. Lactoferrin in Preterm Neonates* Paolo Manzoni, MD

2:30 p.m. Caffeine for Apnea of Prematurity Trial: Barbara Schmidt, MD Outcomes at Age 5 Years*

3:00 p.m. NICHD Support Trial Follow-Up Outcomes Myriam Peralta Carcelen, MD, MPH Yvonne E. Vaucher, MD, MPH

3:40 p.m. Discussion & Audience Questions

4:00 p.m. Adjourn

* Talk includes 10 minutes for audience questions and discussion. ** Breaks include music and slides by Sheldon Korones, MD.

SCHEDULE December 4-6, 2011

PostersPosters will be accepted for continuous display during Coffee Breaks and before and after Receptions. Posters must be on a subject that is beingpresented at the meeting. For more information on abstract requirements and submission, please check our website – www.HotTopics.org

General InformationCourse Overview The goal of this meeting is to review current levels of evidenceand practice in the areas of neonatology and perinatology. Theprogram will include talks and discussion on the newest researchin the prevention and treatment of complications in the neonate,as well as long-term follow-up for the NICU graduate.

Site The program will be held at the Omni Shoreham Hotel inWashington, D.C. The four-diamond Omni Shoreham is nestledon 11 acres in picturesque Rock Creek Park in the northwestsection of the city, and is only steps away from the National Zoo.The hotel is located 8 miles from Reagan National Airport and28 Miles from Dulles International Airport.

Accommodations Rooms have been reserved at the Omni Shoreham Hotel at aspecial conference rate of $203 per night single or doubleoccupancy, not including sales tax. Please make your reservationsthrough the Omni Shoreham Hotel’s Reservation Department at(202) 234-0700, (800) THE-OMNI or (800) 843-6664.

Reservations can also be faxed to (202) 756-5145. Please ask to beassigned to the Hot Topics in Neonatology® room block in orderto receive the special conference rate. The conference rate is onlyavailable for reservations made before Thursday, November 10,2011 and is based on availability.

Americans with Disabilities Act In accordance with the Americans with Disabilities Act, theNemours/Alfred I. DuPont Hospital for Children will providemodifications in teaching methodologies to accommodateindividual needs. To request disability accommodations, contactthe Office of Continuing Medical Education at least 15 days inadvance of the program at (302) 651-6750.

FeesThe conference registration fee is $750 for the General SessionRoom and $500 for the Audio/Visual Room. There is a specialrate of $450 for nurses and fellows in the AV room only. None ofthe above registration fees include AMA PRA Category 1Credit™, but all include the course materials and refreshmentsnoted on the schedule.

Accreditation Nemours is accredited by the Accreditation Council forContinuing Medical Education (ACCME) to provide continuingmedical education for physicians.

Nemours designates this live activity for a maximum of 12.0AMA PRA Category 1 Credits™. Physicians should only claimthe credit commensurate with the extent of their participation inthe activity.

AMA PRA Category 1 Credit™To register for AMA PRA Category 1 Credit™, please choose the credit section on the registration form. There will be anadditional charge of $50.

RegistrationAdvance registration is required and should be received byNovember 14, 2011. All registrations received by this date will beconfirmed via email. Registration is limited and will be honoredin the order of the date received.

To Register with a Check: Return the completed registration form with full payment to theContinuing Medical Education Office, Nemours, P.O. Box 269,Wilmington, DE 19899, USA. Please make check payable in U.S.dollars to “Nemours.”

To Register with a Credit Card:If you are paying by MasterCard, VISA, American Express orDiscover Card, please complete the registration form foundonline at www.hottopics.org.

Cancellation Policy A refund less a $100 processing fee will be given for WRITTENcancellations received before November 1, 2011. No refunds will be given after this date. Nemours is not responsible forcancellation or change fees assessed by hotels, airlines or travelagencies.

Disclosure Policy As a provider accredited by the ACCME, Nemours must ensurebalance, independence, objectivity and scientific rigor in itseducational activities. All faculty involved in the development ofCME content are required to disclose to Nemours their relevantfinancial relationships. An individual has a relevant financialrelationship if he/she has a financial relationship in any amountoccurring in the last 12 months with a commercial interest whoseproducts or services are discussed in the CME activity contentover which the individual has control. Nemours has policies inplace to resolve potential financial conflicts of interest. Relevantfinancial relationships will be disclosed to the activity audience.

Commercial Support This program may be supported in part by unrestrictededucational grants in accordance with ACCME Standards. At thetime of this printing, a list of commercial supporters was notavailable. Appropriate acknowledgement will be given to allexhibitors and supporters in conference materials and at the timeof the meeting.

FOR MORE INFORMATIONContact: Karen BidusNemours/Alfred I. duPont Hospital for Children Office of Continuing Medical Education(302) 651-6752 | info@hottopics.org

Name: ___________________________________________________________________________________________

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Title/Degree:_______________________________________________________________________________________

Profession/Specialty: _________________________________________________________________________________

Employer/Practice:__________________________________________________________________________________

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Address to which confirmation should be mailed: _____________________________________________________________

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REGISTRATION FORM

December 4-6, 2011Omni Shoreham Hotel

Washington, D.C.

REGISTRATION DEADLINE: FOR MORE INFORMATIONKaren Bidus (302) 651-6752 | info@hottopics.org

REGISTERING WITH A CREDIT CARD? Visit HotTopics.org for easy online registration.

SEND FORM WITH CHECK TO:NemoursOffice of Continuing Medical EducationP.O. Box 269, Wilmington, DE 19899 USAMake check payable in U.S. dollars to “Nemours.”Please include registrant’s name on the check.

Fees: Full payment is due with registration

o $750 Registration only (does not include CME)

o $450 for NNP/Fellow Special Rate – AV room only (does not include CME)

o $500 Audio/Visual Room (does not include CME)

o $ 50 for AMA PRA Category 1 Credit(s)™

Syllabus format: Please select oneo CD/DVD o Print

NOVEMBER 14, 2011

c/o The Nemours FoundationContinuing Medical EducationP.O. Box 269Wilmington, DE 19899 USA

For over 30 years, Hot Topics has been THE premiere neonatal conference withmore than 1,000 neonatologists and perinatologists attending each year.

SCHEDULED TOPICS INCLUDE:

Late Effects of Anesthesia in InfantsPrenatal Surgery for Spina Bifida-MOMS TrialPrevention of Preterm Birth

Visit PedsEducation.orgYour source for Continuing Medical Education from Nemours©2011 The Nemours Foundation. Nemours is a registered trademark of the Nemours Foundation.

December 4-6, 2011Omni Shoreham Hotel | Washington, D.C.Top Speakers and Distinguished Guest DiscussantsCritical Reviews and Debate about Promising New TherapiesPoster Sessions

Stem Cells for HIETelemedicineBrain Cooling

Jerold F. Lucey, MD and Jay S. Greenspan, MD invite you to attend