Kingdom of Saudi Kingdom of Saudi ArabiaArabia
King Fahd HospitalJeddah
Internal Medical Department
Dengue Dengue FeverFever By: Dr.wail Bajhmoum
Wednesday 21/5/2008 ; 16/5/1429
Background
Frequency
Race ; Sex and Age
Transmission
Mortality/Morbidity
Clinical Presentation
Treatment
Our hospital statistic
BackgroundBackground
Dengue fever–like illnesses were described in Chinese medical writings dating back to 265 AD.
In 1789, Benjamin Rush, MD, published an account of a dengue fever epidemic that had occurred in Philadelphia in 1780.
The first epidemic of dengue hemorrhagic fever was described in Manila in 1953.
FrequencyFrequency Dengue virus causes about 100
million cases of acute febrile disease annually, including more than 500,000 reported cases of DHF/DSS.
Currently, dengue is endemic in 112 countries.
Race ; Age and SexRace ; Age and Sex
Ethnicity is nonspecific
All ages are susceptible.
Both sexes have the same incidence, however, fewer cases have been reported more in men than in women.
TransmissionTransmission
o by mosquito vectors Aedes aegypti in the sub-tropical and tropical Americas
Aedes albopictus in Asia
Aedes Aegypti the Dengue VectorAedes Aegypti the Dengue Vector
Mortality/MorbidityMortality/Morbidity
• Treated DHF/DSS is associated with a 3% mortality rate.
• Untreated DHF/DSS is associated with a 50% mortality rate.
Clinical PresentationClinical Presentation
Rash – petechial, diffuse erythematous or morbilliform
Hemorrhagic manifestations – epistaxis, petechiae, gum bleeding
Leukopenia Thrombocytopenia Lymphadenopathy
Breakbone fever
Infection can lead to DHF, resulting in renal failure and DSS
TreatmentTreatment
No vaccine available, treatment is supportive
Our hospital statistic
Range of Patients Age
10 30 50
Year
Pati
en
t
21 - 34 Year
% Male Vs. %Female Patients
27%
73%
Positive IgM Vs.
Nigative Patients
Positive IgM
Patients, 72%
Negative IgM
Patients, 28%
% Saudi Vs. Non Saudi w ith
Positive IgM
Non Saudi 51%
Saudi 49%
4 Months Patients Vs.
Total Patients
11
60
%Male Vs. %Female with
PositiveIgM
Female 33%
Male 67%
Thank you