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1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures None Learning Objectives By the end of the workshop, participants will be able to: Describe common obstacles in the diagnosis and treatment of depression in the Asian elderly Describe cultural aspects of communication Understand key differentiating features between Major Depression and Dementia Outline Epidemiology Obstacles to diagnosis Cultural aspects of communication Depression vs. Dementia
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Page 1: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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9/18/2017

Depression in the Asian Elderly

Descartes Li, M.D.Clinical ProfessorUniversity of California, San Francisco

disclosures None

Learning Objectives

By the end of the workshop, participants will be able to:• Describe common obstacles in the diagnosis and

treatment of depression in the Asian elderly• Describe cultural aspects of communication• Understand key differentiating features between Major

Depression and Dementia

Outline

EpidemiologyObstacles to diagnosis

Cultural aspects of communicationDepression vs. Dementia

Page 2: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Outline

EpidemiologyObstacles to diagnosis

Cultural aspects of communicationDepression vs. Dementia

Case Vignette

An 80-year-old monolingual Chinese retired male plumber is brought in by his wife for evaluation of depression.

What is the likelihood he is depressed?

Depression in Among Asian Americans

Survey of 1,747 adults, 18-65 years of agePredictive factors: social stress, measured by past traumatic events and recent negative life events.

Takeuchi et al. Lifetime and Twelve-Month Prevalence Rates of Major Depressive Episodes and Dysthymia Among Chinese Americans in Los

Angeles. Am J Psychiatry 1998; 155:1407–1414.

Lifetime rates: 12-month rates

6.9% MDE5.2% dysthymia

3.4% MDE0.9% dysthymia

Depression in Among Aged Asian Americans

• Groups divided in to 18-29, 30-49, 50-65 • Age 50-65 twice as likely to have

depressive or dysthymic episode• Immigration at age 41-65, three times

more at risk for depression than 0-20, and two times 21-40.

Takeuchi et al. Lifetime and Twelve-Month Prevalence Rates of Major Depressive Episodes and Dysthymia Among Chinese Americans in Los

Angeles. Am J Psychiatry 1998; 155:1407–1414.

Page 3: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Prevalence Rate of Depression in Chinese elderly (in China)

Community-dwelling elderly

11.6%

Elderly medical inpatients 18.1%

P<0.001

Li N et al. Prevalence of depression and its associated factors among Chinese elderly people: A comparison study between community-based population and hospitalized population. Psychiatry Res. 2016 Sep 30;243:87-91. doi: 10.1016/j.psychres.2016.05.030. Epub 2016 May 27.

Depression in Among Aged Asian Americans

• Population Study of Chinese Elderly in Chicago (PINE) study,

• U.S. Chinese older adults aged 60 years and above, n = 3159

• phq-9

Dong X, Chen R, Li C, Simon MA. Understanding depressive symptoms among community-dwelling Chinese older adults in the Greater Chicago area. J Aging Health. 2014;26:1155–1171. doi:10.1177/0898264314527611

Depression in Among Aged Asian Americans

Dong X, Chen R, Li C, Simon MA. Understanding depressive symptoms among community-dwelling Chinese older adults in the Greater Chicago area. J Aging Health. 2014;26:1155–1171. doi:10.1177/0898264314527611

Severity PHQ-9 score

Prevalence in past two weeks

Minimal 1-4 37.3%Mild 5-9 13.3%Moderate 10-14 2.8%Severe >15 1.1%

Depression in Among Aged Asian Americans

3.5% of the participants had suicidal thoughts in the last 2 weeks.

Dong X, Chen R, Li C, Simon MA. Understanding depressive symptoms among community-dwelling Chinese older adults in the Greater Chicago area. J Aging Health. 2014;26:1155–1171. doi:10.1177/0898264314527611

Risk factors: Older age, being female, not being married , lower income, having been in the community for fewer years, lower overall health status, poorer quality of life, and worsening health status over the last year were positively correlated with any depressive symptoms.

Page 4: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Case Vignette

An 80-year-old monolingual Chinese retired male plumber is brought in by his wife for evaluation of “low energy”.

What is the likelihood he is depressed?

Very likely

Outline

EpidemiologyObstacles to diagnosis

Cultural aspects of communicationDepression vs. Dementia

Case Vignette

An 80-year-old monolingual Chinese retired male plumber is brought in by his wife for evaluation of low energy.

What are the most common obstacles in your assessment?

Common problems in evaluation and management of depression

in the Asian elder:

• Co-morbid medical problems• Interview barriers: linguistic, cultural• Differentiating between depression and

dementia• Definition of depression and stigma• Differentiating between major depressive

disorder and “situational” depression

Page 5: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Common problems in evaluation and management of depression

in the Asian elder:

• Co-morbid medical problems• Interview barriers: linguistic, cultural• Differentiating between depression

and dementia• Definition of depression and stigma• Differentiating between major depressive

disorder and “situational” depression

Case Vignette

A 81-year-old monolingual Vietnamese woman with recent heart attack presents in your outpatient clinic with depression for 4 weeks. She reports 5 pound weight loss, little energy or interest in life, poor sleep, feelings of worthlessness/hopelessnes, and thoughts of death and suicide.

Case Vignette(continued)

She has been taking aspirin, atorvastatin, metoprolol, lisinoprilfor the past four weeks. She also uses zolpidem (Ambien) frequently to calm her nerves and for sleep. Her husband reports that her current depressive symptoms are very similar to the ones she experienced three years earlier when she was hospitalized for depression.

What are common causes of depressed mood?

Case Vignette(continued)

Discussion:a. recent diagnosis (Adj rxn)b. this could be a recurrence (MDD) c. Due to a General Medical Conditiond. multiple medications can cause

depression (Substance-induced Mood Disorder)

e. Overuse of zolpidem (Substance abuse)

Page 6: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Outline

EpidemiologyObstacles to diagnosis

Cultural aspects of communicationDepression vs. Dementia

Cultural Identity

Cultural Aspects of Communication

• Direct vs. indirect(video)

• Verbal vs. non-verbal emphasis(taking the history)

Joy Luck Club, 3min

https://youtu.be/WhtjwGZlaew

Page 7: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Elements of non-verbal communication

• Kinesics (eye contact, facial expression)

• Proxemics• Paralanguage (silences,

rhythm and time)• Objectics• Emotional Expressivity

(“inhibited” or “repressed” in a cultural context)

https://en.wikipedia.org/wiki/Nonverbal_communication (basic Wikipedia introduction to the topic)

https://www.helpguide.org/articles/relationships-communication/nonverbal-communication.htm

Website developed with Harvard Health Publications, with several more useful links at the bottom

Outline

EpidemiologyObstacles to diagnosis

Cultural aspects of communicationDepression vs. Dementia

Case Vignette71yo man

complains of poor memory and depressed mood.

How would you differentiate between dementia and depression?

Major Neurocognitive Disorder

Cognitive impairment due to depression

Insight Not aware Aware and concerned

Course Slow, often subtle (onset over month/years)

More rapid(onset over days and weeks)

Social skills Maintained Lost

Memory Loss of recent, not remote memory. Random memory loss

Effort Fair Poor, or variable

Bottom Line:

May not be distinguishable, or may be co-morbid

Page 8: Depression in Asian Elderly 20170916 - UCSF CME1 9/18/2017 Depression in the Asian Elderly Descartes Li, M.D. Clinical Professor University of California, San Francisco disclosures

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Montreal Cognitive Assessment Test

(MoCA)Google: “Mocatest.org”

Outline

EpidemiologyObstacles to diagnosis

Cultural aspects of communicationDepression vs. Dementia

San Francisco Bay Area Mental Heath Resources

Richmond Area Multi-Services3626 Balboa Street San Francisco, CA 94121 (415) 668-5955 [email protected]

Chinatown/North Beach Mental Health Services729 Filbert StreetPh: 415-352-2000

Asian Community Mental Health Services310 - 8th Street, Suite 201 Oakland, CA 94607 (510) 451-6729 www.acmhs.org

On Lok Senior Health Services1333 Bush Street San Francisco, CA 94109 (415) 292-8888 [email protected]

ReferencesAmerican Association of Retired Persons Minority Affairs Initiative. (1987). A Portrait of Older Minorities.

Washington, DC: AARP. Hendricks, J., & Hendricks, C. D. (1986). Aging in Mass Society: Myths and Realities. Boston: Little, Brown

and Co. Kii, T. (1984). Asians. In E. B. Palmore (Ed.), Handbook on the Aged in the United States. Westport, CT:

Greenwood Press. Kim, P. (1990). "Asian-American Families and the Elderly." In M. S. Harper (Ed.), Minority Aging: Essential

Curricula Content for Selected Health and Allied Health Professions. Health Resources and Services Administration, Department of Health and Human Services. DHHS Publication No. HRS-(P-DV-90-4). Washington, DC: U.S. Government Printing Office.

Manuel, R., & Reid, J. (1982). "A Comparative Demographic Profile of the Minority and Nonminority Aged." In R. Manuel (Ed.),Minority Aging. Westport, CT: Greenwood Press.

Sakauye, K. (1990). "Differential Diagnosis, Medication, Treatment and Outcomes: Asian American Elderly. " In M. S. Harper (Ed.), Minority Aging: Essential Curricula Content for Selected Health and Allied Health Professions (pp.-331-340). Health Resources and Services Administration, Department of Health and Human Services. DHHS Publication No. HRS (P-DV-90-4). Washington, DC: U.S. Government Printing Office.

• Culture, Illness and Care, by Kleinman A, Eisenberg L, and Good B. Annals of Internal Medicine, 1978, 88:251-258.

• Behavioral Health Care of Asian Americans. Western Journal of Medicine Sept 2002; 176: 217-279.• Working with Interpreters, by Faust, S, and Drickey R. The Journal of Family Practice, 1986, 22: 131-

138.• Mental Health Care for Asian Americans and Pacific Islanders. – from Mental Health: Culture, Race, and

Ethnicity. Supplement to Mental Health: A Report of the Surgeon General. (2001). U.S. Department of Health and Human Services, Public Health Service.

• Working with Asian Americans: A Guide for Clinicians. Ed. Evelyn Lee. The Guilford Press 1997.

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Thank you!


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