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Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde Leefstijl
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Page 1: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Determinants and mechanism from the earliest moment in life and health during the lifecourse?

Gezonde Voeding

&

Gezonde Leefstijl

Page 2: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Pregnancy Birth 1 10 20 40 80 years Prepregnancy

=Preconception

Developmental Origins of Health and Disease

Preconceptie & zwangerschapsperiode zijn ‘window of opportunity’

voor gedragsverandering van huidige en toekomstige generaties

Page 3: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Evidence-based leefstijlinterventies = gedragsverandering

Prochaska & Diclemente’s transtheoretical model:

readiness to behavioral change

Bandura’s social cognitive theory: self-efficacy

Fogg: motivation, ability and triggers

ASE Model: attitude, social influences and self-efficacy

Page 4: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde
Page 5: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

couples contemplating pregnancy

2 consultations < 3 months

personal screening (questionnaires,

anthropometrics, laboratory)

personal advises (intervention)

2007-2012: 3,500 couples

30% reduction in lifestyle risk factors

Hammiche et al, Hum Reprod 2011

>65% enhanced pregnancy chance

Twigt et al, Hum Reprod 2012

Preconception clinic tailored on nutrition and lifestyle

Page 7: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Websites

• 6 billion mobile phones

• 2.3 billion smart phones

• wellness, prevention, self-management

• patient- centered & healthcare professional centered

• 430 pregnancy apps for pregnancy

Tripp et al., Women Birth 2014;27:64-7

Page 8: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Benefits Barriers

At any time and place Effectiveness?

Anonymously Cost effectiveness?

Personalised Reimbursement

Continuous coaching Biomarkers, anthropometrics

Cheap I Interoperability

eHealth care solutions

• 6 billion mobile phones

• 2.3 billion smart phones

• wellness, prevention, self-management

• patient- centered & healthcare professional centered

• 430 pregnancy apps for pregnancy

Tripp et al., Women Birth 2014;27:64-7

Page 9: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde
Page 10: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Smarter Pregnancy Platform 3.0 CE1 Personal lifestyle coaching

Couples and health care professionals

Multifunctional device independent platform:

• Folic acid, vegetables, fruits, smoking, alcohol

• Modules for safe medication use (IVF, CVD..)

hospital appointments, physical exercise

• Vitamine D

• 3 recipes/week, vouchers folic acid, pregnancy test

www.slimmerzwanger.nl www.slimmerzwanger.nl/nl/demo-en.php www.slimmerzwanger.nl/onderzoek

Page 11: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde
Page 12: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde
Page 13: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde
Page 14: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Preconception & antenatal clinic 86% participation 6% no smartphone 8% other reasons Survey 65% compliance 26 weeks coaching 49-74% positive usability

0

10

20

30

40

50

60

Screening Coaching General

%

1 (disagree)

2

3

4

5 (agree)

Survey results 2012-2013

Compliance and usability

Page 15: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Disagree (%) Agree (%)

0 1 2 3

I have more attention for my nutrition 0 14 25 61

I have more attention for my lifestyle 0 15 23 62

Slimmer Zwanger supports me very much 0 27 39 34

I will not take a subscription when I have to pay 0 6 18 77

I like that the program is also for my partner 0 3 51 46

Survey results 2012-2013

Page 16: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Efficacy:

Fruit, vegetables: 20-38%

Folic acid supplement use: 60-71%

Smoking, alcohol: 13-22%

Pregnancy chance: 19% (14-23%)

Cost-efficacy with assumption of 30% effectiveness

3,0% absolute reduction of subfertility € 13.317 per woman

3,4% absolute reduction Big3-outcome € 10.693 per baby

Survey results 2012-2013

(Cost) efficacy

Page 17: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Implementation of eHealth and mHealth from the earliest moment during the lifecourse

Page 20: Determinants and mechanism from the earliest moment in ... · Determinants and mechanism from the earliest moment in life and health during the lifecourse? Gezonde Voeding & Gezonde

Health

professional

Stakeholders

Gen

practitioner

Midwife

Gynecologist

Geneticists

Public

health

Education

Social media

Marketing Parents

Health

Lifestyle

Environment

Occupation

Income

Consumption

Behavior

Child

Health

Lifestyle

Behavior

Anthropometrics

Health data

Biomarkers

DNA

Lifestyle

Health

Biomarkers

DNA

Lifestyle

Behavior


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