Digital Imaging and Communications in Medicine...

1 Digital Imaging and Communications in Medicine2 (DICOM)

3 Sup 187 - Preclinical Small Animal Imaging Acquisition Context

4 DICOM Standards Committee - Working Group 30 - Small Animal Imaging

5 1300 N. 17th Street Suite 17526 Rosslyn7 VA8 222099 USA10

11 Status: Letter Ballot12 Publication date 2015/09/15

13 This supplement is prepared pursuant to work item: 2015-05-A14 Copyright © 2015 NEMA

1 Table of Contents2 Document History .................................................................................................................................................. 73 ....................................................................................................................................................................... 74 Closed Issues ....................................................................................................................................................... 85 ....................................................................................................................................................................... 86 Scope and Field of Application ................................................................................................................................ 107 DICOM PS3.16. Content Mapping Resource .............................................................................................................. 118 A. Structured Reporting Templates (Normative) ...................................................................................................... 119 Acquisition Context SR IOD Templates. ........................................................................................................... 1110 TID ttt01. Preclinical Small Animal Image Acquisition Context ............................................................................ 1111 TID ttt10. Biosafety Conditions .................................................................................................................... 1412 TID ttt21. Animal Housing .......................................................................................................................... 1413 TID ttt22. Animal Feeding ........................................................................................................................... 1714 TID ttt30. Anesthesia ................................................................................................................................. 1815 TID ttt31. Medications and Mixture Medications .............................................................................................. 2016 TID ttt40. Heating Conditions ...................................................................................................................... 2117 TID ttt50. Circadian Effects ......................................................................................................................... 2218 TID ttt70. Physiological Monitoring Performed During Procedure ........................................................................ 2219 TID ttt82. Exogenous Substance Administration .............................................................................................. 2320 TID 9002. Medication, Substance, Environmental Exposure .................................................................................. 2421 C. Acquisition Context Module and Protocol Context Templates (Normative) ................................................................ 2622 TID 3471. PET Covariates Acquisition Context ................................................................................................... 2623 B. DCMR Context Groups (Normative) .................................................................................................................. 2724 ................................................................................................................................................................. 2725 CID yesnoonly. Yes-No Only .......................................................................................................................... 2726 CID presentabsentonly. Present-Absent Only ..................................................................................................... 2727 CID bsl01. Biosafety Levels ............................................................................................................................ 2728 CID bsl02. Biosafety Control Reasons .............................................................................................................. 2829 CID sex01. Sex - Male Female or Both ............................................................................................................. 2830 CID rom01. Animal Room Types ..................................................................................................................... 2831 CID dsp01. Device Reuse .............................................................................................................................. 2932 CID bed01. Animal Bedding Material ................................................................................................................ 2933 CID she01. Animal Shelter Types .................................................................................................................... 2934 CID fed01. Animal Feed Types ........................................................................................................................ 2935 CID fed02. Animal Feed Sources ..................................................................................................................... 3036 CID fed03. Animal Feeding Methods ................................................................................................................ 3037 CID wat01. Water Types ................................................................................................................................ 3138 CID ans01. Anesthesia Category Code Type for Small Animal Anesthesia ............................................................... 3139 CID aqi01. Anesthesia Category Code Type from Anesthesia Quality Initiative (AQI) .................................................. 3140 CID ans02. Anesthesia Induction Code Type for Small Animal Anesthesia ............................................................... 3241 CID aqi02. Anesthesia Induction Code Type from Anesthesia Quality Initiative (AQI) .................................................. 3242 CID ans03. Anesthesia Maintenance Code Type for Small Animal Anesthesia .......................................................... 3243 CID aqi03. Anesthesia Maintenance Code Type from Anesthesia Quality Initiative (AQI) ............................................. 3344 CID ans04. Airway Management Method Code Type for Small Animal Anesthesia ..................................................... 3345 CID aqi04. Airway Management Method Code Type from Anesthesia Quality Initiative (AQI) ....................................... 3346 CID ans05. Airway Management Sub-Method Code Type for Small Animal Anesthesia .............................................. 3447 CID aqi05. Airway Management Sub-Method Code Type from Anesthesia Quality Initiative (AQI) ................................. 3448 CID ans06. Medication Type Code Type for Small Animal Anesthesia ..................................................................... 3449 CID aqi06. Medication Type Code Type from Anesthesia Quality Initiative (AQI) ........................................................ 3550 CID ans07. Medication for Small Animal Anesthesia ............................................................................................ 3751 CID ans08. Inhalational Anesthesia Agents for Small Animal Anesthesia ................................................................. 3752 CID ans09. Injectable Anesthesia Agents for Small Animal Anesthesia .................................................................... 3853 CID ans09b. Premedication Agents for Small Animal Anesthesia ........................................................................... 3854 CID ans10. Neuromuscular Blocking Agents for Small Animal Anesthesia ................................................................ 3955 CID ans11. Ancillary Medications for Small Animal Anesthesia .............................................................................. 3956 CID ans11b. Carrier Gases for Small Animal Anesthesia ...................................................................................... 3957 CID ans11c. Local Anesthetics for Small Animal Anesthesia ................................................................................. 4058 CID ans12. Phase of Procedure Requiring Anesthesia ......................................................................................... 40

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60 Page 2Sup 187 - Preclinical Small Animal Imaging Acquisition Context

1 CID ans13. Phase of Surgical Procedure Requiring Anesthesia ............................................................................. 402 CID ans14. Phase of Imaging Procedure Requiring Anesthesia ............................................................................. 413 CID pha01. Phase of Animal Handling .............................................................................................................. 414 CID hea01. Heating Method ........................................................................................................................... 415 CID hea02. Temperature Sensor Device Component Type for Small Animal Procedures ............................................ 426 CID exo01. Exogenous Substance Types .......................................................................................................... 427 CID exo05. Exogenous Substance ................................................................................................................... 438 CID exo10. Tumor Graft Histologic Type ........................................................................................................... 439 CID exo11. Fibrils ......................................................................................................................................... 4410 CID exo12. Viruses ....................................................................................................................................... 4411 CID exo13. Cytokines .................................................................................................................................... 4412 CID exo14. Toxins ........................................................................................................................................ 4513 CID exo30. Exogenous Substance Administration Sites ....................................................................................... 4514 CID exo50. Exogenous Substance Tissue of Origin ............................................................................................. 4515 CID proc01. Preclinical Small Animal Imaging Procedures .................................................................................... 4616 CID pri. Position Reference Indicator for Frame of Reference ................................................................................ 4717 CID 11. Route of Administration ...................................................................................................................... 4718 CID 100. Quantitative Diagnostic Imaging Procedures ......................................................................................... 4819 CID 230. Yes-No .......................................................................................................................................... 4820 CID 244. Laterality ........................................................................................................................................ 4921 CID 6092. Quantitative Concepts for Usage, Exposure ......................................................................................... 4922 CID 6046. Units of Follow-up Interval ................................................................................................................ 4923 CID 6090. Relative Usage, Exposure Amount .................................................................................................... 4924 CID 6091. Relative Frequency of Event Values ................................................................................................... 5025 CID 6093. Qualitative Concepts for Usage, Exposure Amount ............................................................................... 5026 CID 6094. Qualitative Concepts for Usage, Exposure Frequency ........................................................................... 5027 D. Controlled Terminology Definitions (Normative) .................................................................................................. 5128 ................................................................................................................................................................. 5129 ................................................................................................................................................................. 5130 DICOM PS3.17. Explanatory Information ................................................................................................................... 5631 ..................................................................................................................................................................... 5632 XXXX. Preclinical Small Animal Imaging Acquisition Context (Informative) ............................................................... 5633 ............................................................................................................................................................. 5634 XXXX.1. ................................................................................................................................................ 5635 XXXX.1.1. Example of housing and anesthesia for PET-CT .......................................................................... 5636 XXXX.1.2. Example of exogenous substance administration to encode tumor cell line ........................................ 6237 XXXX.1.3. Informative References ........................................................................................................... 6338 DICOM PS3.3. Information Object Definitions ............................................................................................................. 6439 3. Definitions ................................................................................................................................................... 6440 A. Composite Information Object Definitions (Normative) .......................................................................................... 6441 A.35.x. Acquisition Context SR IOD .................................................................................................................. 6442 A.35.x.1. Acquisition Context SR Information Object Description ........................................................................ 6443 A.35.x.2. Acquisition Context SR IOD Entity-Relationship Model ........................................................................ 6444 A.35.x.3. Acquisition Context SR IOD Module Table ........................................................................................ 6445 A.35.x.3.1. Acquisition Context SR IOD Content Constraints ......................................................................... 6546 A.35.x.3.1.1. Value Type .................................................................................................................... 6547 A.35.x.3.1.2. Relationship Constraints .................................................................................................. 6548 A.35.x.3.1.3. Template Constraints ...................................................................................................... 6549 DICOM PS3.4. Service Class Specifications .............................................................................................................. 6650 B. Storage Service Class (Normative) ................................................................................................................... 6651 B.3.1.4. Related General SOP Classes (A-ASSOCIATE-RQ) ................................................................................ 6652 B.5. Standard SOP Classes ............................................................................................................................ 6653 B.5.1.5. Structured Reporting Storage SOP Classes ............................................................................................ 6654 I. Media Storage Service Class (Normative) ........................................................................................................... 6655 I.4. Media Storage Standard SOP Classes ........................................................................................................ 6756 I.4.1.2. Structured Reporting Storage SOP Classes ............................................................................................. 6757 DICOM PS3.6. Data Dictionary ............................................................................................................................... 6858 A. Registry of DICOM Unique Identifiers (UIDs) (Normative) ...................................................................................... 6859 ..................................................................................................................................................................... 6860 DICOM PS3.2. Conformance .................................................................................................................................. 69

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1 A. DICOM Conformance Statement Template (Normative) ........................................................................................ 69

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1 List of Tables2 TID ttt01. Preclinical Small Animal Image Acquisition Context ........................................................................................ 123 TID ttt10. Biosafety Conditions ................................................................................................................................ 144 TID ttt21. Animal Housing ...................................................................................................................................... 145 TID ttt22. Animal Feeding ....................................................................................................................................... 176 TID ttt30. Anesthesia ............................................................................................................................................. 187 TID ttt31. Medications and Mixture Medications .......................................................................................................... 208 TID ttt40. Heating Conditions .................................................................................................................................. 219 TID ttt50. Circadian Effects ..................................................................................................................................... 2210 TID ttt70. Physiological Monitoring Performed During Procedure .................................................................................... 2211 TID ttt82. Parameters ............................................................................................................................................ 2312 TID ttt82. Exogenous Substance Administration .......................................................................................................... 2313 TID 9002. Parameters ........................................................................................................................................... 2514 TID 9002. Medication, Substance, Environmental Exposure .......................................................................................... 2515 TID 3471. PET Covariates Acquisition Context ........................................................................................................... 2616 CID yesnoonly. Yes-No Only .................................................................................................................................. 2717 CID presentabsentonly. Present-Absent Only ............................................................................................................. 2718 CID bsl01. Biosafety Levels .................................................................................................................................... 2719 CID bsl02. Biosafety Control Reasons ...................................................................................................................... 2820 CID sex01. Sex - Male Female or Both ..................................................................................................................... 2821 CID rom01. Animal Room Types ............................................................................................................................. 2822 CID dsp01. Device Reuse ...................................................................................................................................... 2923 CID bed01. Animal Bedding Material ........................................................................................................................ 2924 CID she01. Animal Shelter Types ............................................................................................................................ 2925 CID fed01. Animal Feed Types ................................................................................................................................ 3026 CID fed02. Animal Feed Sources ............................................................................................................................. 3027 CID fed03. Animal Feeding Methods ........................................................................................................................ 3028 CID wat01. Water Types ........................................................................................................................................ 3129 CID ans01. Anesthesia Category Code Type for Small Animal Anesthesia ....................................................................... 3130 CID aqi01. Anesthesia Category Code Type from Anesthesia Quality Initiative (AQI) .......................................................... 3131 CID ans02. Anesthesia Induction Code Type for Small Animal Anesthesia ....................................................................... 3232 CID aqi02. Anesthesia Induction Code Type from Anesthesia Quality Initiative (AQI) .......................................................... 3233 CID ans03. Anesthesia Maintenance Code Type for Small Animal Anesthesia .................................................................. 3234 CID aqi03. Anesthesia Maintenance Code Type from Anesthesia Quality Initiative (AQI) ..................................................... 3335 CID ans04. Airway Management Method Code Type for Small Animal Anesthesia ............................................................. 3336 CID aqi04. Airway Management Method Code Type from Anesthesia Quality Initiative (AQI) ............................................... 3337 CID ans05. Airway Management Sub-Method Code Type for Small Animal Anesthesia ...................................................... 3438 CID aqi05. Airway Management Sub-Method Code Type from Anesthesia Quality Initiative (AQI) ......................................... 3439 CID ans06. Medication Type Code Type for Small Animal Anesthesia ............................................................................. 3540 CID aqi06. Medication Type Code Type from Anesthesia Quality Initiative (AQI) ................................................................ 3541 CID ans07. Medication for Small Animal Anesthesia .................................................................................................... 3742 CID ans08. Inhalational Anesthesia Agents for Small Animal Anesthesia ......................................................................... 3743 CID ans09. Injectable Anesthesia Agents for Small Animal Anesthesia ............................................................................ 3844 CID ans09b. Premedication Agents for Small Animal Anesthesia ................................................................................... 3945 CID ans10. Neuromuscular Blocking Agents for Small Animal Anesthesia ........................................................................ 3946 CID ans11. Ancillary Medications for Small Animal Anesthesia ...................................................................................... 3947 CID ans11b. Carrier Gases for Small Animal Anesthesia .............................................................................................. 3948 CID ans11c. Local Anesthetics for Small Animal Anesthesia ......................................................................................... 4049 CID ans12. Phase of Procedure Requiring Anesthesia ................................................................................................. 4050 CID ans13. Phase of Surgical Procedure Requiring Anesthesia ..................................................................................... 4051 CID ans14. Phase of Imaging Procedure Requiring Anesthesia ..................................................................................... 4152 CID pha01. Phase of Animal Handling ...................................................................................................................... 4153 CID hea. Heating Method ....................................................................................................................................... 4254 CID hea02. Temperature Sensor Device Component Type for Small Animal Procedures .................................................... 4255 CID exo01. Exogenous Substance Types .................................................................................................................. 4256 CID exo05. Exogenous Substance ........................................................................................................................... 4357 CID exo10. Tumor Graft Histologic Type ................................................................................................................... 4358 CID exo11. Fibrils ................................................................................................................................................. 44

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1 CID exo12. Viruses ............................................................................................................................................... 442 CID exo13. Cytokines ............................................................................................................................................ 453 CID exo14. Toxins ................................................................................................................................................ 454 CID exo30. Exogenous Substance Administration Sites ............................................................................................... 455 CID exo50. Exogenous Substance Tissue of Origin ..................................................................................................... 456 CID proc01. Preclinical Small Animal Imaging Procedures ............................................................................................ 467 CID pri. Position Reference Indicator for Frame of Reference ........................................................................................ 478 CID 11. Route of Administration .............................................................................................................................. 479 CID 100. Quantitative Diagnostic Imaging Procedures ................................................................................................. 4810 CID 230. Yes-No .................................................................................................................................................. 4811 CID 244. Laterality ................................................................................................................................................ 4912 CID 6092. Quantitative Concepts for Usage, Exposure ................................................................................................. 4913 CID 6046. Units of Follow-up Interval ........................................................................................................................ 4914 CID 6090. Relative Usage, Exposure Amount ............................................................................................................ 5015 CID 6091. Relative Frequency of Event Values ........................................................................................................... 5016 CID 6093. Qualitative Concepts for Usage, Exposure Amount ....................................................................................... 5017 CID 6094. Qualitative Concepts for Usage, Exposure Frequency ................................................................................... 5018 D-1. DICOM Controlled Terminology Definitions ......................................................................................................... 5119 A.35.x-1. Acquisition Context SR IOD Modules ........................................................................................................... 6420 A.35.x-2. Relationship Content Constraints for Acquisition Context SR IOD ...................................................................... 6521 B.3-3. Standard and Related General SOP Classes .................................................................................................... 6622 B.5-1. Standard SOP Classes ................................................................................................................................. 6623 I.4-1. Media Storage Standard SOP Classes .............................................................................................................. 6724 A-1. UID Values ................................................................................................................................................... 6825 A-3. Context Group UID Values ............................................................................................................................... 6826 A.1-2. UID Values ................................................................................................................................................. 69

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1 Document History2 ContentDateD o c u m e n t3 Version4 First draft2014/12/15015 Expand description of housing and handling; add anesthesia model derived from relevant6 parts of AQI schema.

2015/01/0402

7 Revised description based on 2015/01/16 t/con discussion and other feedback; improve8 anesthesia medications model and include mixtures; remove biosafety (BSL) information9 and Specific Pathogen Free (SPF) status monitoring since they does not affect interpretation;10 removed animal positioning during acquisition; remove unchanged PS3.3 Annex C sections

2015/03/1403

11 Reorganize by procedure-related phase, factor feeding out of housing, add more phases12 (including induction, preparation), add start/end dates and times for housing (esp. for13 interventions), fill out heating conditions, assign codes, restore BSL information, add detailed14 example.

2015/03/2404

15 Update after WG6 first read, and assigned supplement number 187.2015/03/250516 Add context groups for premed and local anesthetics, more inhalational and injectable17 anesthetics, restore open issue about single value for housing unit air changes etc., add18 depth for bedding, enrichment manufacturer.

2015/04/0906

19 Draft for WG 6 Review before Public Comment2015/06/030720 Public Comment.2015/06/170821 Post public Comment - add exogenous substances2015/08/020922 Post public Comment - update exogenous substances (include stereotactic coordinates,23 laterality, distinguish role of therapy from model, generalize concept for tumor cell graft to24 just tumor graft), update relationship constraints, add missing PS3.4 stuff, populate SCT25 and UMLS codes in context group tables.

2015/08/0410

26 Add DSC work item number, resolve public comments (none), open issues, to do list.2015/09/011127 Generalize definitions and rename context group related to grafts, since not just cell28 suspension grafted (may be chunks of tissue); add position reference indicator for stereotactic29 coordinates.

2015/09/0112

30 Make animal feeding invocation 1-n to handle supplements and treats; extend feeding mode31 to include restricted diet and treats; add brain and tumor to administration site and intratumor32 to route of administration. Add outline of interconnected templates in lieu of separate figure33 (since it can be hyperlinked and conveys the same information). Update anesethesia example34 to split out different induction methods into separate examples. Checked IOD Value Type35 and Relationship Constraint tables against new templates as well as invoked standard36 templates. Extended list of procedure codes to cover brain. Populated exogenous substance37 context groups. Closed all open issues and removed section. Completed TODO items and38 removed section.

2015/09/1313

39 Incorporate WG 6 day 1 feedback for letter ballot.2015/09/141440 Letter ballot text.2015/09/1515

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1 Closed Issues2 A Structured Report is used to encode the Acquisition Context, rather than encoding the information in the images in3 new Modules or the generic Acquisition Context Module.

1

4 Existing SR templates in PS3.16 make use of the concept of acquisition context, especially for cardiovascular waveform5 acquisitions, but TID 3530 "Hemodynamic Acquisition Context", for example, is too specific and lacks relevant content6 for reuse in this supplement.

2

7 The acquisition context SR templates are added to Annex A of PS3.16, not Annex C, despite the latter being entitled8 "Acquisition and Protocol Context Templates". Annex A is for Structured Report templates, which these are, as distinct9 from the templates for the Acquisition Context Module's Acquisition Context Sequence (0040,0555) Attribute that are10 defined in Annex C. Accordingly, Annex C is renamed to indicate that it applies only to Acquisition Context Module11 templates.

3

12 Depth is needed for bedding, since weight/volume are not useful unless cage dimensions are also known.413 Do need separate manufacturer for rack/cage bottom/lid. Need product name and code but not serial #. Do not need14 to factor out into common macro. Noted that manufacturers products and names may change over time.

5

15 Coding or defining quantity of enrichment material is currently beyond the state of the art. For now, text description,16 manufacturer and present or not is sufficient.

6

17 It is important to record the presence and type of devices to increase animal activity in cage because this may affect18 metabolism. Coding it is not necessary, and a text description and present or not is sufficient.

7

19 The full set of AQI route types does not need to be added to CID 11. The only specific route that needs to be added for20 small animals is retro-orbital.

8

21 Codes for local anesthetics have not been added, since systemic anesthetics are usually utilized.922 There is a need to model mixtures of anesthetic agents, so re-use the AQI MixtureMedications mechanism in the23 anesthesia record.

10

24 Specific Pathogen Free status monitoring information is not described, because it does not affect interpretation.1125 Animal positioning during acquisition is not included since it will be encoded in the images and there is no need to26 replicate it.

12

27 Feeding and watering are described separately from housing description.1328 WG6: Do not use "Procedure Reported", since we are not producing a "report" for the procedure; use Procedure Code29 instead, which can be inherited from TID 1005 Procedure Context via TID 1001 Observation Context.

14

30 We need not need to include number of passages of a cell line in exogenous substances.1531 A laterality modifier (left or right) is needed for the site of exogenous substance administration.1632 Stereotactic surgical coordinates are need for exogenous substances, e.g., that have been administered to the brain.1733 Species and strain identification is not described (replicated) in the observation context templates; rather it is encoded34 in DICOM Attributes in the top level data set (CP 1478).

18

35 A specific context group for imaging procedures for preclinical small animals is needed and has been populated, since36 the range of concepts needed is small and preclinical acquisition and management systems may not have access to37 an ordering/scheduling system to provide codes via a worklist. LOINC codes are used preferentially when available.

19

38 An IOD and SOP Class specific to the Acquisition Context root templates is required, since a generic SR SOP Class is39 thought not to be sufficient for the use case. The IOD and SOP Class are described as being specific to Acquisition40 Context in general, but not specifically Preclinical Small Animal Acquisition Context, in order to allow reuse for other for41 other purposes that might require acquisition context.

20

42 The SR Document Title (root container node) is specific to Preclinical Small Animal Acquisition Context, rather than43 being a generic Acquisition Context title, which qualifies the use of the generic IOD and SOP Class to be the more44 specific use case.

21

45 No cross-references are defined between the Acquisition Context SR instance and the acquired images, since they will46 likely be produced by different systems; commonality of the Study Instance UID should suffice (and that can be obtained47 via Modality Worklist (MWL)). If there is no MWL, then commonality of Study Date and Study Time may be the best that48 can be achieved (without merging/coercion at post-processing time).

22

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1 Acquisition Context is not modeled as part of Procedure Context per se, since the latter is used mainly for identification,2 not description, of the procedure, and burying the acquisition context detail inside Procedure Context would be confusing.

23

3 The scope of what to encode is largely confined to significant factors that affect imaging outcome (e.g., metabolic effects),4 and which do not replicate imaging technique information that is (or should be) encoded in the images themselves (e.g.,5 reconstruction technique, image processing, timing of one image relative to another, subject positioning in the scanner,6 and information related to contrast and/or radiopharmaceutical injection. Other substances administered that are related7 to the anesthesia and/or other aspects of the procedure (e.g., cardiovascular agents) may be described in the Acquisition8 Context, as may exogenous substances (e.g., injected tumor cells) that are part of the experimental paradigm as opposed9 to being related to the imaging procedure per se.

24

10 With respect to acquisition timing, no special synchronization mechanisms are needed, beyond those already standardized11 in the Synchronization Module.

25

12 All of the subordinate templates that described the acquisition context are optional, since it is expected that different13 experiments will have different requirements for what needs to be populated, and different deployments will have different14 capabilities and priorities with respect to what can and needs to be recorded (by this mechanism). Also, there is no15 prohibition on creating multiple different instances for the same animal and acquisition, e.g., one to describe handling,16 one to describe anesthesia and another to describe exogenous substances (such as tumor cells), particularly since this17 information may be generated by different systems.

26

18 The human (AQI) anesthesia model has been followed fairly closely ... this is thought to be sufficient and appropriate19 for small animals as well as humans and has been reviewed by the working group (WG25). Additional concepts specific20 to routes of administration and other values sets that are used only in animals have been added where necessary.

27

21 The TID 9002 “Medication, Substance, Environmental Exposure” is used as the basis for a specialized TID ttt8222 “Exogenous Substance Administration” template, but not for anesthesia medications, for which the AQI model is used23 as a basis.

28

24 The relatively simple description of Circadian effects is thought to be sufficient without being overly complicated.2925 The short list of coded feed types is thought to be sufficient for now and may be extended later if necessary (CID fed0126 “Animal Feed Types”).

30

27 Limited types of physiological monitoring that were used, are described (ECG and respiration) and are thought to be28 sufficient (see TID ttt70 “Physiological Monitoring Performed During Procedure”)? If monitoring is recorded and included29 with the study in DICOM form, it is encoded elsewhere (e.g., in waveform instances).

31

30 As is common practice with other generic templates, medication-related units have not been more constrained and are31 left to the discretion of the implementer or user (e.g., as per AQI CommonUnit type, or specific to each invocation, e.g.,32 concentration, volume).

32

33 Covariates that require measurement (such as blood glucose measurements for PET) are not included since other34 mechanisms are available and intended to be reused per human imaging practice (e.g., the existing Acquisition Context35 templates intended for encoding in the images, such as TID 3471 “PET Covariates Acquisition Context”).

33

36 There is no need to record total number or rows and columns in cage rack, nor which housing units are populated versus37 empty?

34

38 There is no need to record explicitly that transport cage is the same as home cage (+/- different lid).3539 There is no need to describe more about the imaging carrier/sled/chamber, such as whether it is completely enclosed40 or not, whether there is a bite bar, presence or absence or number of stereotactic fixation points, presence or absence41 of limb ties, or the presence or absence of fiducial markers.

36

42 There is no need for a more sophisticated model of biological sex for animals and handlers than m/f/mixed, e.g., for43 transsexual handlers or animal experiments on such things.

37

44 The Classification code for exogenous substances is left unconstrained, and specific new content items have been45 added for tissue and taxonomic rank (species) of origin, since the single concept of Classification was not sufficient46 (indeed its intent in the original TID 9002 “Medication, Substance, Environmental Exposure” from which it is inherited47 remains mysterious).

38

48 A single value for housing unit air changes, average temperature, humidity and airflow is sufficient; based on feedback49 received, a range is not needed, since even though a range may be specified in procedures and requirements, for an50 actual instance, a nominal value (normally within the procedurally required range) can be recorded.

39

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1 Scope and Field of Application2 This Supplement defines use-cases and templates for storage of information related to acquisition of small animal images during3 preclinical research.

4 Acquisition Context is a "description of the conditions present during data acquisition" (quoted from the text of PS3.3 Section C.7.6.145 Acquisition Context Module).

6 Traditionally, all attributes that describe an image acquisition are defined as specific Attributes (Data Elements) in a modality-specific7 IOD. This approach works extremely well when image objects have very specific applications and when the domain from which the8 descriptive concepts are drawn is well understood and clearly defined. When the visible light image object family was introduced, an9 alternative and more general mechanism was added to the standard, using lists of coded name-value pairs to specify acquisition10 content information, rather than depending on SOP-class-specific sets of traditional Attributes. The name-value pairs are encoded in11 the Acquisition Context Module. Using coded entries has benefits and disadvantages. One of the advantages is the ability to use12 coding schemes defined by other organizations to define names and value sets for concepts. The "acquisition context" idea was in-13 troduced to DICOM by Dean Bidgood and is well described in his article on the subject: Bidgood WD, Bray B, Brown N, Mori AR,14 Spackman KA, Golichowski A, et al. Image Acquisition Context: Procedure Description Attributes for Clinically Relevant Indexing and15 Selective Retrieval of Biomedical Images. Journal of the American Medical Informatics Association : JAMIA. 1998 Aug 17;6(1):61–75.16 available at http://www.ncbi.nlm.nih.gov/pubmed/9925229.

17 Both approaches assume that the Acquisition Context is known prior to encoding the image in DICOM, and that it is known to the18 device encoding the DICOM image (the modality). In some cases, information about the acquisition that is relevant to the interpretation19 of the imaging may not be known to the modality. This is particularly the case in small animal preclinical research, where a myriad of20 factors that affect quantitative analysis need to be recorded, which would be overwhelming if required to be captured at the modality21 console user interface. Though it would be possible to add this information by post-processing of the acquired images, WG 30 has22 concluded that it is preferable to encode the Acquisition Context in a separate standalone composite instance.

23 The type of information to be recorded needs to be in a structured form, and many of the concepts are expected to be available in24 external lexicons. This is particularly the case for descriptions of experimental conditions, animal physiology and animal handling.25 Accordingly, the DICOM Structured Report (SR) mechanism is a natural choice of encoding. The Acquisition Context Module in the26 images will remain unpopulated.

27 The Acquisition Context SR instances will usually be in the same Study as the acquired images.

28 This supplement defines a new DICOM SR root template and supporting templates, as well as an IOD and SOP Class specific to that29 template to facilitate interoperability.

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http://www.ncbi.nlm.nih.gov/pubmed/9925229

1 DICOM PS3.16 Content Mapping Resource2 A Structured Reporting Templates (Normative)3 Amend DICOM PS3.16 - Content Mapping Resource - Structured Reporting Templates to add the following:

4 Acquisition Context SR IOD Templates

5 The Templates that comprise the Acquisition Context SR are interconnected as follows:

6 • TID ttt01 “Preclinical Small Animal Image Acquisition Context”

7 • TID 1204 "Language of Content Item and Descendants"

8 • TID 1001 "Observation Context"

9 • TID ttt10 “Biosafety Conditions”

10 • TID ttt21 “Animal Housing”

11 • TID ttt22 “Animal Feeding”

12 • TID ttt40 “Heating Conditions”

13 • TID ttt50 “Circadian Effects”

14 • TID ttt70 “Physiological Monitoring Performed During Procedure”

15 • TID ttt30 “Anesthesia”

16 • TID ttt31 “Medications and Mixture Medications”

17 • TID 9002 “Medication, Substance, Environmental Exposure”

18 • TID ttt82 “Exogenous Substance Administration”

19 TID ttt01 Preclinical Small Animal Image Acquisition Context20 This root template encodes a description of the conditions present during and related to data acquisition for a single imaging procedure.

21 Note

22 1. It is not expected that a single instance be used to describe the entire life of an animal, unless it is sacrificed after a23 single procedure. Rather, separate instances will be used for separate procedures, though there may be some duplication24 of common information, such as about the home cage environment.

25 2. It is expected that an SR instance encoded using this template will be contained in the same Study as other instances26 created during the procedure, e.g. with a common Study Instance UID. If this is not practical, e.g., due to recording on27 a separate device without use of a shared Modality Worklist, then commonality of other Study level attributes may be28 necessary to link procedures (and possibly coerce the Study Instance UID to a common value).

29 Type:30 Extensible

31 Order:32 Non-Significant

33 Root:34 Yes

35 - Draft -


1 Table TID ttt01. Preclinical Small Animal Image Acquisition Context

2 Value Set ConstraintConditionReq3 Type

VMConcept NameVTRel withParent

NL

4 Root nodeM1EV (ddd001, DCM,5 "Preclinical Small Animal6 Imaging Acquisition Context")

CONTAINER1

7 M1DTID 1204 "Language of8 Content Item and9 Descendants"

INCLUDEHASCONCEPTMOD

>2

10 M1DTID 1001 "Observation11 Context"

INCLUDEHAS OBSCONTEXT

>3

12 U1DTID ttt10 “Biosafety13 Conditions”

INCLUDECONTAINS>5

14 M1-nEV (ddd005, DCM, "Animal15 handling during specified16 phase")

CONTAINERCONTAINS>6

17 DCID pha01 “Phase of18 Animal Handling”

M1EV (ddd006, DCM, "Phase ofanimal handling")

CODECONTAINS>>7

19 U1EV (111526, DCM,20 "DateTime Started")

DATETIMECONTAINS>>8

21 U1EV (111527, DCM,22 "DateTime Ended")

DATETIMECONTAINS>>9

23 U1DTID ttt21 “Animal Housing”INCLUDECONTAINS>>1024 U1-nDTID ttt22 “Animal Feeding”INCLUDECONTAINS>>1125 U1DTID ttt40 “Heating26 Conditions”

INCLUDECONTAINS>>12

27 U1DTID ttt50 “Circadian Effects”INCLUDECONTAINS>>1328 U1DTID ttt70 “Physiological29 Monitoring Performed During30 Procedure”

INCLUDECONTAINS>>14

31 U1DTID ttt30 “Anesthesia”INCLUDECONTAINS>1532 $ContainerConcept = EV33 (10160-0, LN, "History Of34 Medication Use")

35 $CodeConcept = EV36 (111516, DCM,37 "Medication Type")

38 $Route = DCID 11 “Route39 of Administration”

U1DTID 9002 “Medication,Substance, EnvironmentalExposure”

INCLUDECONTAINS>16

40 - Draft -


http://s.details.loinc.org/LOINC/10160-0.html




NL

3 $ContainerConcept = EV4 (ddd400, DCM,5 "Exogenous substance")

6 $CodeConcept = DCID7 exo01 “Exogenous8 Substance Types”

9 $CodeValue = DCID exo0510 “Exogenous Substance”

11 $Route = DCID 11 “Route12 of Administration”

13 $Site = DCID exo30

14 $TissueOfOrigin = DCID15 exo50

16 $TaxonomicRankOfOrigin17 = DCID 7454 "Animal18 Taxonomic Rank Values"

U1DTID ttt82 “ExogenousSubstance Administration”

INCLUDECONTAINS>17

19 Content Item Descriptions

20 A single pre-coordinated code describing the general type of imaging procedure can be described using TID21 1005 Row 9 Procedure Code (included in TID 1001). For small animal (as opposed to human) imaging, this will22 likely describe a whole body acquisition in a modality-specific manner and the use of contrast and/or23 radiopharmaceutical. E.g., whole body FDG PET, or whole body DCE-MRI.

24 May be redundant with (or default to) the value present in the top level data set in Procedure Code Sequence25 (0008,1032) of the General Study Module.

26 Species and strain identification is not described in TID 1001; rather it is encoded in DICOM Attributes in the top27 level data set.

Row 3

28 The biosafety conditions are expected to be consistent across all phases of handling, so are not described29 separately per-phase.

Row 5

30 The period of time during which the phase is defined, i.e., during which the animal was managed in the specified31 conditions. This may be more important for interpretation for some phases (e.g., transport) than others (e.g., at32 rest in the home cage), and hence is optional.

Rows 8-9

33 The outline of subordinate templates follows the pattern of categories of Animal Housing, Care, and Physiologic34 Monitoring information described in [Stout et al 2013].

Rows 10-14

35 Animal feeding is 1-n to allow encoding of dietary supplements and treats in addition to the regular diet.Row 1136 A single anesthesia event is normally assumed for a single procedure, though the template included can include37 multiple pre-, intra- and post-procedure descriptions.

Row 15

38 Used to describe pharmaceuticals administered that are not described elsewhere, in particular, those that are39 not described as anesthesia medications, and those that are not described in the images (e.g., contrast,40 radiopharmaceuticals). This includes therapy (such as chemotherapy, immunotherapy) and similar interventions41 that may be the subject of the research.

42 The value set of $CodeValue is not defined, given the vast range of possible codes and coding schemes for43 drugs or medicaments that might be used. Nor are value sets for $Classification or $Site defined.

Row 16

44 - Draft -


1 Used to describe non-pharmaceutical exogenous substances administered, such as cells or other tumor graft,2 fibrils, viruses, cytokines and toxins that describe the "model" upon which the research is being performed, as3 distinct from the "therapeutic intervention" (Row 16) that may be the purpose of the research. The Classification4 parameter is not constrained by any value set.

Row 17

5 TID ttt10 Biosafety Conditions6 This template encodes a description of the biosafety conditions applicable to research small animals.

7 Type:8 Extensible


11 Table TID ttt10. Biosafety Conditions

12 Value Set ConstraintConditionReq TypeVMConcept NameVTRel with ParentNL13 M1EV (ddd010, DCM, "Biosafety14 conditions")

CONTAINER1

15 DCID bsl01 “Biosafety16 Levels”

U1EV (F-0061F, SRT, "Biosafetylevel")

CODECONTAINS>2

17 DCID bsl02 “Biosafety18 Control Reasons”

U1EV (ddd011, DCM, "Reasonfor biosafety controls")

CODECONTAINS>2

19 U1EV (121106,20 DCM,"Comment")

TEXTCONTAINS>4


22 A brief description of any pertinent or unusual biosafety requirements.Row 4

23 TID ttt21 Animal Housing24 This template encodes a description of housing of animals, e.g., in home cages, holders for imaging, etc., over an interval during25 which environmental and handling conditions are relatively homogenous.

26 Note

27 1. Only "static" parameters of the design and setup are recorded, and "nominal" values for environmental conditions such28 as humidity and temperature, but not "dynamic" parameters that might vary during one housing interval, and potentially29 be monitored, such as oxygen or ammonia levels, temperature, humidity, urine or fecal corticosterone levels, etc.

30 2. Values for product names and codes are expected to be accurate at the time the information is recorded, recognizing31 that products may evolve over time.



36 Table TID ttt21. Animal Housing


VMConcept NameVTRel with ParentNL

39 M1EV (ddd120, DCM, "Animal40 housing")

CONTAINER1

41 DCID rom01 “Animal42 Room Types”

U1EV (ddd121, DCM, "Animalroom type")

CODECONTAINS>2

43 U1EV (ddd121b, DCM, "Animal44 room identifier")

TEXTCONTAINS>2b

45 - Draft -




3 E.g., "Innovive, San4 Diego, CA".

U1EV (ddd125, DCM, "Housingmanufacturer")

TEXTCONTAINS>3

5 E.g., "Innorack IVC6 Mouse 3.5".

U1EV (ddd126, DCM, "Housingrack product name")

TEXTCONTAINS>4

7 U1EV (ddd127, DCM, "Housing8 rack product code")

TEXTCONTAINS>5

9 E.g., "Innocage Mouse".U1EV (ddd128, DCM, "Housing10 unit product name")

TEXTCONTAINS>6

11 E.g., "M-BTM".U1EV (ddd129, DCM, "Housing12 unit product code")

TEXTCONTAINS>7

13 E.g., "Innocage IVC14 Mouse Large Filter".

U1EV (ddd130, DCM, "Housingunit lid product name")

TEXTCONTAINS>8

15 E.g., "MV6".U1EV (ddd131, DCM, "Housing16 unit lid product code")

TEXTCONTAINS>9

17 UNITS = EV ({racks},18 UCUM, "racks")

U1EV (ddd140, DCM, "Number ofracks per room")

NUMCONTAINS>10

19 UNITS = EV ({housing20 units}, UCUM, "housing21 units") or EV ({cages},22 UCUM, "cages")

U1EV (ddd141, DCM, "Number ofhousing units per rack")

NUMCONTAINS>11

23 U1EV (ddd142, DCM, "Housing24 unit location in rack")

TEXTCONTAINS>12

25 UNITS = EV ({animals},26 UCUM, "animals")

U1EV (ddd143, DCM, "Number ofanimals within same housing

27 unit")

NUMCONTAINS>13

28 DCID sex01 “Sex - Male29 Female or Both”

U1EV (ddd144, DCM, "Sex ofanimals within same housing

30 unit")

CODECONTAINS>14

31 DCID sex01 “Sex - Male32 Female or Both”

U1EV (ddd145, DCM, "Sex ofhandler")

CODECONTAINS>15

33 UNITS = EV (d, UCUM,34 "days")

U1EV (ddd150, DCM, "Totalduration in housing")

NUMCONTAINS>16


U1EV (ddd151, DCM, "Housingchange interval")

NUMCONTAINS>17

37 UNITS = EV (h, UCUM,38 "hours")

U1EV (ddd152, DCM, "Manualhandling interval")

NUMCONTAINS>18

39 U1EV (ddd153, DCM, "Housing40 unit movement")

TEXTCONTAINS>19

41 UNITS = EV (cm,42 UCUM, "cm")

U1EV (ddd160, DCM, "Housingunit width")

NUMCONTAINS>20


U1EV (ddd161, DCM, "Housingunit height")

NUMCONTAINS>21


U1EV (ddd162, DCM, "Housingunit length")

NUMCONTAINS>22

47 DCID yesnoonly48 “Yes-No Only”

U1EV (ddd170, DCM, "Housingindividually ventilated")

CODECONTAINS>23

49 UNITS = EV (/h, UCUM,50 "/hour")

U1EV (ddd172, DCM, "Airchanges")

NUMCONTAINS>24

51 - Draft -




3 UNITS = EV (Cel,4 UCUM, "C")

U1EV (C90380, NCIt,"Environmental temperature")

NUMCONTAINS>25

5 UNITS = EV (%, UCUM,6 "%")

U1EV (C90395, NCIt, "Housinghumidity")

NUMCONTAINS>26

7 DCID dsp01 “Device8 Reuse”

U1EV (ddd175, DCM, "Housingunit reuse")

CODECONTAINS>27

9 DCID bed01 “Animal10 Bedding Material”

U1EV (C90366, NCIt, "Beddingmaterial")

CODECONTAINS>28

11 U1EV (C90366, NCIt, "Bedding12 material")

TEXTCONTAINS>29


U1EV (ddd180, DCM, "Beddingmanufacturer")

TEXTCONTAINS>30

15 U1EV (ddd181, DCM, "Bedding16 product name")

TEXTCONTAINS>31

17 U1EV (ddd182, DCM, "Bedding18 product code")

TEXTCONTAINS>32

19 UNITS = EV (ml,20 UCUM, "ml")

U1EV (ddd183, DCM, "Beddingvolume")

NUMCONTAINS>33

21 UNITS = EV (g, UCUM,22 "g")

U1EV (ddd184, DCM, "Beddingmass")

NUMCONTAINS>34

23 UNITS = EV (mm,24 UCUM, mm")

U1EV (ddd185, DCM, "Beddingdepth")

NUMCONTAINS>34b


U1EV (C90365, NCIt, "Beddingchange")

NUMCONTAINS>35

27 DCID presentabsentonly28 “Present-Absent Only”

U1EV (ddd192, DCM, "Enrichmentmaterial present")

CODECONTAINS>36

29 E.g., "Nylabone".U1EV (ddd191, DCM, "Enrichment30 manufacturer")

TEXTCONTAINS>36b

31 U1EV (ddd190, DCM, "Enrichment32 material")

TEXTCONTAINS>37

33 DCID presentabsentonly34 “Present-Absent Only”

U1EV (ddd193, DCM, "Exerciserdevice present")

CODECONTAINS>38

35 E.g., "Innowheel"U1EV (A-17200, SRT, "Exerciser36 device")

TEXTCONTAINS>39

37 DCID she01 “Animal38 Shelter Types”

U1EV (ddd195, DCM, "Sheltertype")

CODECONTAINS>40


U1EV (ddd196, DCM, "Sheltermanufacturer")

TEXTCONTAINS>41

41 E.g., "InnoDome".U1EV (ddd197, DCM, "Shelter42 product name")

TEXTCONTAINS>42

43 E.g., "INNODOME".U1EV (ddd198, DCM, "Shelter44 product code")

TEXTCONTAINS>43

45 U1EV (121106, DCM,"Comment")TEXTCONTAINS>44


47 The type and identifier of the entire room in which, for example, one or more racks of housing units is48 located, not the housing unit itself.

Row 2 and 2b

49 - Draft -


1 The manufacturer is expected to be the same for all housing unit components, rack, bottom and lid.Row 32 The position in the rack is encoded as text since it may be an "identifier" or a description. It is not a set of3 numeric (e.g., row, column) or coded (e.g., top, bottom or middle) values, since there are too many possible4 arrangements.

Row 12

5 The number of animals usually applies to a single housing unit, but may also be used to describe the6 number of animals imaged simultaneously in a multi-animal imaging carrier or support device ("chamber",7 "holder", etc.).

Row 13

8 These may be internal or external dimensions, and are intended to provide an approximation of the living9 space and shape available.

Rows 20-22

10 Description of measured or monitored or nominal values of temperature and humidity. The means of11 maintaining these conditions, if relevant, is described elsewhere (e.g., in the case of peri-procedural12 temperature control, in TID ttt40 “Heating Conditions”).

Rows 25-26

13 The bedding material may be described as a code or text, or both. The codes do not distinguish between14 methods of sterilization of the bedding material (e.g., irradiation, autoclaving or other heat treatment), since15 that is not a relevant factor for image interpretation. The definition of the NCIt concept is "that which16 comprises the place where a subject sleeps".

Rows 28-29

17 The definition of the NCIt concept is "a replacement of the existing materials that make up the sleeping18 area of a subject", and is used here to specify the interval between bedding changes.

Row 35

19 The presence or absence of enrichment material is coded, but the type is not, and may be described as20 text, e.g., "facial tissue", "cotton (nesting material)".

Row 36-37

21 The presence or absence of an exercise device is coded, but the type is not, and may be described as22 text.

Row 38-39

23 TID ttt22 Animal Feeding24 This template encodes a description of feeding and watering of animals, over an interval during which conditions are relatively homo-25 genous.

26 Note

27 1. No specific time interval during which the diet is applicable is described.

28 2. Values for product names and codes are expected to be accurate at the time the information is recorded, recognizing29 that products may evolve over time.



34 Table TID ttt22. Animal Feeding



37 M1EV (PA-00600, SRT,38 "Feeding")

CONTAINER1

39 DCID fed01 “Animal Feed40 Types”

U1EV (C-F5000, SRT, "Animalfeed")

CODECONTAINS>2

41 DCID fed02 “Animal Feed42 Sources”

U1EV (ddd205, DCM, "Feedsource")

CODECONTAINS>3

43 E.g., "Harlan Teklad,44 Madison, WI"

U1EV (ddd200, DCM, "Feedmanufacturer")

TEXTCONTAINS>4

45 E.g., "NIH31 Open46 Formula Mouse/Rat47 Sterilizable Diet".

U1EV (ddd201, DCM, "Feedproduct name")

TEXTCONTAINS>5

48 - Draft -




3 E.g., "7017".U1EV (ddd202, DCM, "Feed4 product code")

TEXTCONTAINS>6

5 DCID fed03 “Animal6 Feeding Methods”

U1EV (C0015746, UMLS,"Feeding method")

CODECONTAINS>7

7 DCID wat01 “Water8 Types”

U1EV (C-10120, SRT, "Water")CODECONTAINS>8

9 DCID fed03 “Animal10 Feeding Methods”

U1EV (C90486, NCIt, "Waterdelivery")

CODECONTAINS>9

11 U1EV (121106, DCM,12 "Comment")

TEXTCONTAINS>10


14 Row

15 TID ttt30 Anesthesia16 This template encodes a description of the anesthesia applied during a procedure (e.g., imaging of research small animals).

17 Note

18 This template combines selected concepts from the AQI schema elements, their complex types, and their children:

19 • AnesthesiaMethodSet (type AnesthesiaMethodSetType). See http://www.aqihq.org/aqischdoc/AnesthesiaMethodSet.html20 and http://www.aqihq.org/aqischdoc/AnesthesiaMethodSetType.html.

21 • AirwayManagementSet (type AirwayManagementSetType). See http://www.aqihq.org/aqischdoc/AirwayManagementSet.html22 and http://www.aqihq.org/aqischdoc/AirwayManagementSetType.html.

23 • MedicationsSet (type MedicationsSetType). See http://www.aqihq.org/aqischdoc/MedicationsSet.html and http://24 www.aqihq.org/aqischdoc/MedicationsSetType.html.

25 Used by permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).



30 Table TID ttt30. Anesthesia



NL

33 M1EV (P1-0512A, SRT,34 "Administration of anesthesia")

CONTAINER1

35 M1EV (ddd300, DCM,36 "Anesthesia Method Set")

CONTAINERCONTAINS>2

37 M1-nEV (ddd301, DCM,38 "Anesthesia Method")

CONTAINERCONTAINS>>3

39 DCID ans0140 “Anesthesia Category41 Code Type for Small42 Animal Anesthesia”

M1EV (ddd302, DCM,"Anesthesia Category")

CODECONTAINS>>>4

43 U1EV (ddd303, DCM,44 "Anesthesia SubCategory")

TEXTCONTAINS>>>5

45 - Draft -


http://www.aqihq.org/aqischdoc/AnesthesiaMethodSet.html

http://www.aqihq.org/aqischdoc/AnesthesiaMethodSetType.html

http://www.aqihq.org/aqischdoc/AirwayManagementSet.html

http://www.aqihq.org/aqischdoc/AirwayManagementSetType.html

http://www.aqihq.org/aqischdoc/MedicationsSet.html

http://www.aqihq.org/aqischdoc/MedicationsSetType.html


http://aqihq.org/



NL

3 U1EV (DF-0068E, SRT,4 "Anesthesia Start Time")

DATETIMECONTAINS>>>6

5 U1EV (DF-0070B, SRT,6 "Anesthesia Finish Time")

DATETIMECONTAINS>>>7

7 DCID ans028 “Anesthesia Induction9 Code Type for Small10 Animal Anesthesia”

U1EV (P1-C0012, SRT,"Anesthesia Induction")

CODECONTAINS>>>8

11 DCID ans0312 “Anesthesia13 Maintenance Code14 Type for Small Animal15 Anesthesia”

U1EV (P1-C001A, SRT,"Anesthesia Maintenance")

CODECONTAINS>>>9

16 U1121106, DCM, "Comment")TEXTCONTAINS>>>1017 M1EV (ddd310, DCM, "Airway18 Management Set")

CONTAINERCONTAINS>11

19 M1-nEV (P0-0409B, SRT, "Airway20 Management")

CONTAINERCONTAINS>>12

21 DCID ans04 “Airway22 Management Method23 Code Type for Small24 Animal Anesthesia”

M1EV (ddd312, DCM, "AirwayManagement Method")

CODECONTAINS>>>13

25 DCID ans05 “Airway26 Management27 Sub-Method Code Type28 for Small Animal29 Anesthesia”

M1EV (ddd313, DCM, "AirwaySub-Management Method")

CODECONTAINS>>>14

30 M1-nEV (ddd320, DCM,31 "Medications Set")

CONTAINERCONTAINS>15

32 DCID ans12 “Phase of33 Procedure Requiring34 Anesthesia”

M1EV (G-7292, SRT, "ProcedurePhase")

CODECONTAINS>>16

35 M1-nDTID ttt31 “Medications and36 Mixture Medications”

INCLUDECONTAINS>>17


38 If this template is used, at least one description of anesthesia method is required. Note that the specific39 agents used are described separately, as intra-operative medications, per the AQI model.

Rows 1-3

40 These correspond to AQI elements that are named "Time" rather than "DateTime", though their value is a41 DateTime; the DICOM naming convention is used here.

Rows 6-7

42 Only inhalational methods of maintenance are included in this row. Absence of this row implies that the43 (non-inhalational) induction method is used for maintenance.

Row 9

44 The comment corresponds to AQI element "Anesthesia Notes".Row 1045 At least one description of airway management is required.

46 The airway management method also serves as the description of the method of inhalational anesthesia47 delivery, even if it does not involve "management" of the "airway" per se (e.g., delivery via nose cone).

Rows 11-13

48 - Draft -


1 In the AQI model, a single AQI MedicationsSet is used in the AQI IntraOp element to describe intra-operative2 medications.

3 This template allows a more general usage, with one or more Medications Set containers, each of which4 may be qualified by the phase of the procedure (pre-operative, intra-operative or post-operative). The purpose5 of the medication (e.g., general anesthetic) is described in the (111516, DCM, "Medication Type") of the6 included TID ttt31 “Medications and Mixture Medications”.

Rows 15-17

7 TID ttt31 Medications and Mixture Medications8 This template encodes a description of medications (including but not limited to anesthetic agents) used during a procedure (e.g.,9 anesthesia for imaging of research small animals).

10 Note

11 This template combines selected concepts from the AQI schema elements, their complex types, and their children:

12 • Medication (type MedicationType). See http://www.aqihq.org/aqischdoc/Medication.html and http://www.aqihq.org/aqischdoc/13 MedicationType.html.

14 • MixtureMedications (type MixtureMedicationType). See http://www.aqihq.org/aqischdoc/MixtureMedications.html and15 http://www.aqihq.org/aqischdoc/MixtureMedicationType.html.

16 Used by permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).



21 Table TID ttt31. Medications and Mixture Medications



24 M1EV (F-04460, SRT,25 "Medication given")

CONTAINER1

26 U1EV (122081, DCM, "Drug27 start")

DATETIMECONTAINS>2

28 U1EV (122082, DCM, "Drug29 end")

DATETIMECONTAINS>3

30 DCID 11 “Route of31 Administration”

M1EV (G-C340, SRT, "Route ofadministration")

CODECONTAINS>4

32 M1-nEV (R-40826, SRT,33 "Mixture")

CONTAINERCONTAINS>5

34 DCID ans07 “Medication35 for Small Animal36 Anesthesia”

XOR Row18

MC1EV (122083, DCM, "Drugadministered")

CODECONTAINS>>6

37 XOR Row38 17

MC1EV (122083, DCM, "Drugadministered")

TEXTCONTAINS>>7

39 DCID ans06 “Medication40 Type Code Type for41 Small Animal42 Anesthesia”

M1EV (111516, DCM,"Medication Type")

CODECONTAINS>>8

43 UNITS = DCID 82 "Units44 of Measurement"

U1EV (G-C0B7, SRT,"Dosage")

NUMCONTAINS>>9

45 UNITS = DCID 82 "Units46 of Measurement"

U1EV (122093, DCM,"Concentration")

NUMCONTAINS>>10

47 - Draft -


http://www.aqihq.org/aqischdoc/Medication.html

http://www.aqihq.org/aqischdoc/MedicationType.html

http://www.aqihq.org/aqischdoc/MedicationType.html

http://www.aqihq.org/aqischdoc/MixtureMedications.html

http://www.aqihq.org/aqischdoc/MixtureMedicationType.html

http://aqihq.org/


2 AQI Medication type and element correspond to (F-04460, SRT, "Medication given") (situation). (See TID 38063 Cath Procedure).

Row 1

4 AQI DoseStart and DoseEnd elements correspond to (122081, DCM, "Drug start") and (122082, DCM, "Drug5 end") respectively. (See CID 3409 Administration of Drugs/Contrast). If the medication is delivered as a bolus,6 the end time is omitted.

Rows 2-3

7 AQI MedicationRoute corresponds to (G-C340, SRT, "Route of administration"). The existing CID 11 “Route of8 Administration” contains a relevant subset of concepts for the enumerated values of AQI9 MedicationRouteCodeType.

Row 4

10 The AQI schema allows the Medication type not only to describe medications with a single component, but also11 to add MixtureMedications children, each of which is encoded following a similar pattern to the contents of12 Medication, though the start and end time and route of administration are shared. This had been modeled by13 allowing every medication to have one or more mixture children. For medications that are not a mixture, a single14 instance of this row defines the medication (even though the mixture container is still used).

Row 5

15 AQI MedicationName and MixtureMedicationName elements correspond to (122083, DCM, "Drug administered").16 (See TID 3806 Cath Procedure). The medication (e.g., anesthesia agent) can be described with a code or text,17 e.g., (F-61B0A, SRT, "Isoflurane") or "isoflurane".

Rows 6, 7

18 Both AQI MedDose (or MixtureMedDose) and DoseUnits (or MixtureDoseUnits) elements are combined in one19 content item. Units are required to be encoded as UCUM but are not otherwise constrained.

Row 9

20 Both AQI MedConcentration (or MixtureMedConcentration) and MedConcentrationUnit (or21 MixtureMedConcentrationUnit) elements are combined in one content item. Units are required to be encoded22 as UCUM but are not otherwise constrained.

Row 10

23 TID ttt40 Heating Conditions24 This template encodes a description of the heating conditions applied prior to, during or after data acquisition (e.g., during imaging25 of research small animals).



30 Table TID ttt40. Heating Conditions



NL

33 M1EV (ddd040, DCM, "Heating34 conditions")

CONTAINER1

35 DCID ans12 “Phase of36 Procedure Requiring37 Anesthesia”

U1EV (G-7292, SRT, "ProcedurePhase")

CODECONTAINS>2

38 DCID hea01 “Heating39 Method”

U1EV (C0018851, UMLS,"Heating")

CODECONTAINS>3

40 DCID yesnoonly “Yes-No41 Only”

U1EV (ddd210, DCM,"Feedback temperature

42 regulation")

CODECONTAINS>4

43 DCID hea02 “Temperature44 Sensor Device Component45 Type for Small Animal46 Procedures”

U1EV (C50304, NCIt,"Temperature sensor devicecomponent")

CODECONTAINS>5

47 UNITS = EV (Cel, UCUM,48 "C")

U1EV (F-021FF, SRT,"Equipment Temperature")

NUMCONTAINS>6


50 - Draft -


1 Phase during which the conditions are applicable may be implicit in the context of invocation of this template2 (e.g., TID ttt01 “Preclinical Small Animal Image Acquisition Context” Row 7), or explicitly specified.

Row 2

3 The definition (from MESH) is "The application of heat to raise the temperature of the environment, ambient4 or local, or systems for accomplishing this effect".

Row 3

5 This is the nominal temperature of the heating device (e.g., heating pad) and/or the set point of the feedback6 regulation device.

Row 6

7 TID ttt50 Circadian Effects8 This template encodes a description of the Circadian effects relevant during data acquisition (e.g., during imaging of research small9 animals).



14 Table TID ttt50. Circadian Effects



NL

17 M1EV (ddd050, DCM, "Circadian18 effects")

CONTAINER1

19 UNITS = EV (h, UCUM,20 "hours") E.g., 24 hours.

U1EV (ddd214, DCM, "Totalduration of light-dark cycle")

NUMCONTAINS>2

21 UNITS = EV (%, UCUM,22 "%") E.g., 50%.

U1EV (C90419, NCIt, "Lightcycle")

NUMCONTAINS>3

23 E.g., "0700".U1-nEV (ddd215, DCM, "Lights on24 time of day")

TIMECONTAINS>4


26 The definition is "the amount of ambient light/darkness to which a subject is exposed in a period of time"; also27 mapped to CDISC "the period of light that a subject is exposed to in a period of time, usually expressed as the28 amount of time in a 24 hour cycle".

Row 3

29 Can only be encoded if the light-dark cycles are aligned to a 24 hour clock. May be multiple if either multiple30 cycles occur during a 24 hour period, or if the cycle is longer than a 24 hour period and a multiple of 24 hours31 in duration.

Row 4

32 TID ttt70 Physiological Monitoring Performed During Procedure33 This template encodes a description of the physiological monitoring performed during a period of time during or related to a data ac-34 quisition procedure (e.g., imaging of research small animals).



39 Table TID ttt70. Physiological Monitoring Performed During Procedure

40 Value Set ConstraintConditionReq TypeVMConcept NameVTRel with41 Parent

NL

42 M1(P0-005ED, SRT,43 "Physiological monitoring")

CONTAINER1

44 - Draft -


1 Value Set ConstraintConditionReq TypeVMConcept NameVTRel with2 Parent

NL


U1EV (P2-31209, SRT,"Electrocardiographic

5 monitoring")

CODECONTAINS>2


U1EV (P2-22010, SRT,"Monitoring of respiration")

CODECONTAINS>3


9 There is no non-surgical procedure non-specific variant of (P2-34122, SRT, "Monitoring of electrocardiogram at10 surgery"). (P2-31209, SRT, "Continuous electrocardiogram monitoring") is intended for non-procedural (e.g.,11 24-hour) monitoring. So a more generic code for any kind of monitoring is used.

Row 2

12 TID ttt82 Exogenous Substance Administration13 This template provides detailed information on a research subject's exposure to exogenous substances. It is a specialization of the14 more general template TID 9002 “Medication, Substance, Environmental Exposure”.

15 Table TID ttt82. Parameters

16 Parameter UsageParameter Name17 Coded term for the concept name of the CONTAINER, identifying it as an exogenous18 substance.

$ContainerConcept

19 Coded term for the concept name of the CODE, identifying the type of substance.$CodeConcept20 Coded term or Context Group for value of the substance.$CodeValue21 Coded term or Context Group for classification of the substance.$Classification22 Coded term or Context Group for the route of administration of the substance.$Route23 Coded term or Context Group for the anatomical site of administration of the substance$Site24 Coded term or Context Group for the tissue of origin of the substance$TissueOfOrigin25 Coded term or Context Group for the taxonomic rank (e.g., species) of origin of the26 substance

$TaxonomicRankOfOrigin

27 Type:28 Extensible29 Order:30 Significant

31 Table TID ttt82. Exogenous Substance Administration



34 M1$ContainerConceptCONTAINER135 $CodeValueM1-n$CodeConceptCODECONTAINS>236 $ClassificationU1EV (G-C032, SRT,37 "Classification")

CODEHAS CONCEPTMOD

>>3

38 DCID 7450 "Person39 Roles"/>

U1EV (111534, DCM, "Roleof person reporting")

CODEHAS OBSCONTEXT

>>4

40 UNITS = DCID 7456 "Units41 of Measure for Age"

U1EV (111524, DCM, "AgeStarted")

NUMHASPROPERTIES

>>5

42 UNITS = DCID 7456 "Units43 of Measure for Age"

U1EV (111525, DCM, "AgeEnded")

NUMHASPROPERTIES

>>6


DATETIMEHASPROPERTIES

>>7

46 - Draft -






>>8

5 UNITS = DCID 6046 “Units6 of Follow-up Interval”

U1EV (G-7290, SRT,"Duration")

NUMHASPROPERTIES

>>9

7 DCID 230 “Yes-No”U1EV (111528, DCM,8 "Ongoing")

CODEHASPROPERTIES

>>10

9 U1EV (111529, DCM, "Brand10 Name")

TEXTHASPROPERTIES

>>11

11 The unit of measure shall12 be quantity per unit of time

U1DCID 6092 “QuantitativeConcepts for Usage,

13 Exposure”

NUMHASPROPERTIES

>>12

14 DCID 6090 “Relative15 Usage, Exposure Amount”

U1DCID 6093 “QualitativeConcepts for Usage,

16 Exposure Amount”

CODEHASPROPERTIES

>>13

17 DCID 6091 “Relative18 Frequency of Event19 Values”

U1DCID 6094 “QualitativeConcepts for Usage,Exposure Frequency”

CODEHASPROPERTIES

>>14

20 $RouteU1EV (G-C340, SRT, "Route21 of administration")

CODEHASPROPERTIES

>>15

22 $SiteU1EV (G-C581, SRT, "Site23 of")

CODEHASPROPERTIES

>>>16

24 DCID 244 “Laterality”IF Row 1625 has26 laterality

MC1EV (G-C171, SRT,"Laterality")

CODEHAS CONCEPTMOD

>>>>17

27 U1EV (ddd450, DCM,28 "Stereotactic coordinates")

SCOORD3DHASPROPERTIES

>>>18

29 DCID pri “Position30 Reference Indicator for31 Frame of Reference”

U1EV (ddd451, DCM,"Position referenceindicator")

CODEHASPROPERTIES

>>>19

32 $TissueOfOriginU1EV (ddd401, DCM, "Tissue33 of origin")

CODEHASPROPERTIES

>>20

34 $TaxonomicRankOfOriginU1EV (ddd402, DCM,35 "Taxonomic rank of origin")

CODEHASPROPERTIES

>>21


37 Classification is inherited from the more general template TID 9002 “Medication, Substance, Environmental38 Exposure”, and may be supplied as a parameter, but is entirely generic and is not used as an alternative to the39 more specific information provided in other rows, for example, Rows 19 and 20, tissue and taxonomic rank of40 origin.

Row 3

41 Brand name may be used for any type of descriptor or identifier. E.g., a particular cell line might have a designated42 name, such as "MDA-MB-468", which designates a particular human breast cancer cell line.

Row 11

43 Amend existing relevant templates in DICOM PS3.16:

44 TID 9002 Medication, Substance, Environmental Exposure

45 This general template provides detailed information on a patient's medication or substance use, or exposure to environmental factors,46 including type and duration of use or exposure.

47 - Draft -


1 Table TID 9002. Parameters

2 Parameter UsageParameter Name3 Coded term for the concept name of the CONTAINER, identifying it as medication, substance,4 or environmental exposure history.

$ContainerConcept

5 Coded term for the concept name of the CODE, identifying it as medication, substance, or6 environmental exposure.

$CodeConcept

7 Coded term or Context Group for value of the medication, substance, or environmental exposure.$CodeValue8 Coded term or Context Group for classification of the medication, substance, or9 environmental exposure.

$Classification

10 Coded term or Context Group for the route of administration of the medication, substance,11 or route of environmental exposure.

$Route

12 Coded term or Context Group for the anatomical site of administration of the medication,13 substance, or anatomical site of environmental exposure.

$Site

14 Type:15 Extensible16 Order:17 Significant

18 Table TID 9002. Medication, Substance, Environmental Exposure



21 M1$ContainerConceptCONTAINER122 $CodeValueM1-n$CodeConceptCODECONTAINS>223 $ClassificationU1EV (G-C032, SRT,24 "Classification")

CODEHAS CONCEPTMOD

>>3

25 DCID 7450 "Person26 Roles"/>

U1EV (111534, DCM, "Roleof person reporting")

CODEHAS OBSCONTEXT

>>4

27 UNITS = EV (a,28 UCUM, "Year") DCID29 7456 "Units of30 Measure for Age"

U1EV (111524, DCM, "Age31 Started")

NUMHASPROPERTIES

>>5

32 UNITS = EV (a,33 UCUM, "Year") DCID34 7456 "Units of35 Measure for Age"

U1EV (111525, DCM, "Age36 Ended")

NUMHASPROPERTIES

>>6



>>7



>>8

41 UNITS = DCID 604642 “Units of Follow-up43 Interval”

U1EV (G-7290, SRT,"Duration")

NUMHASPROPERTIES

>>9

44 DCID 230 “Yes-No”U1EV (111528, DCM,45 "Ongoing")

CODEHASPROPERTIES

>>10

46 U1EV (111529, DCM, "Brand47 Name")

TEXTHASPROPERTIES

>>11

48 The unit of measure49 shall be quantity per50 unit of time

U1DCID 6092 “QuantitativeConcepts for Usage,Exposure”

NUMHASPROPERTIES

>>12

51 - Draft -




3 DCID 6090 “Relative4 Usage, Exposure5 Amount”

U1DCID 6093 “QualitativeConcepts for Usage,Exposure Amount”

CODEHASPROPERTIES

>>13

6 DCID 6091 “Relative7 Frequency of Event8 Values”

U1DCID 6094 “QualitativeConcepts for Usage,Exposure Frequency”

CODEHASPROPERTIES

>>14

9 $RouteU1EV (G-C340, SRT, "Route10 of administration")

CODEHASPROPERTIES

>>15

11 $SiteU1EV (G-C581, SRT, "Site12 of")

CODEHASPROPERTIES

>>>16

13 DCID 244 “Laterality”IF Row 1614 has15 laterality

MC1EV (G-C171, SRT,"Laterality")

CODEHAS CONCEPTMOD

>>>>17


17 No context group is provided for the value set, but it is recommended that values from a standard18 external coding scheme, such as SRT or NDC, be used. Classification is SCT:278201002,19 UMLS:C0008902, and is completely generic; i.e., it does not specifically refer to any particular20 type of classification.

Row 3 "Classification"

21 If both of these content items are instantiated, the concept names selected for each should match. For22 example, use "Relative dose amount" as the concept name for row 13 with "Relative dose frequency"23 as the concept name for row 14.

Rows 13 & 14

24 Even though the concept name is route of administration, it is also used for route of exposure25 in the case of environmental exposure.

Row 15

26 This pattern of route with a site and laterality modifier follows that used in TID 1002227 Radiopharmaceutical Administration Event Data.

Rows 16 and 17

28 Rename Annex in DICOM PS3.16:

29 C Acquisition Context Module and Protocol Context Templates (Normative)30 For reference (unchanged), existing relevant templates in DICOM PS3.16:

31 TID 3471 PET Covariates Acquisition Context

32 Type:33 Extensible34 Order:35 Non-Significant

36 Table TID 3471. PET Covariates Acquisition Context

37 Value Set ConstraintConditionReq TypeVMConcept NameVT38 UNITS = EV (mmol/l,39 UCUM, "mmol/l")

U1(14749-6, LN, "Glucose")NUMERIC1

40 IFF Row 1 is presentMC1(109081, DCM, "Glucose41 Measurement Date")

DATE2

42 IFF Row 1 is presentMC1(109082, DCM, "Glucose43 Measurement Time")

TIME3

44 - Draft -



1 B DCMR Context Groups (Normative)2 Amend DICOM PS3.16 - Content Mapping Resource - Annex B - DCMR Context Groups (Normative) as follows, to add new Context3 Groups for Preclinical Small Animal Imaging Acquisition Contexts:

4 CID yesnoonly Yes-No Only

5 Type:6 Non-Extensible7 Version:8 yyyymmdd

9 Table CID yesnoonly. Yes-No Only

10 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme11 Designator12 C1298907373066001YesR-0038DSRT13 C1298908373067005NoR-00339SRT

14 Note

15 This context group is intended for use rather than CID 230 "Yes-No" when the value (R-0038A, SRT, "Undetermined") is not16 permissible.

17 CID presentabsentonly Present-Absent Only

18 Type:19 Non-Extensible20 Version:21 yyyymmdd

22 Table CID presentabsentonly. Present-Absent Only

23 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme24 Designator25 C015031252101004PresentG-A203SRT26 C0442733272519000AbsentR-4089BSRT

27 Note

28 This context group is intended for use rather than CID 240 "Normal-Abnormal" when the value (R-40271, SRT, "Presence29 Undetermined") is not permissible.

30 CID bsl01 Biosafety Levels


33 Version:34 yyyymmdd

35 Table CID bsl01. Biosafety Levels

36 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme37 Designator38 C1443934409600007Biosafety level 1R-41E4DSRT39 C1443937409603009Biosafety level 2R-41E4ESRT40 C1443938409604003Biosafety level 3R-41E4FSRT41 C1443939409605002Biosafety level 4R-41E50SRT

42 - Draft -


1 CID bsl02 Biosafety Control Reasons

2 Type:3 Extensible


6 Table CID bsl02. Biosafety Control Reasons

7 UMLS Concept Unique IDSNOMED-CT Concept8 ID

Code MeaningCode ValueCoding SchemeDesignator

9 C0079021409595003Biohazardous materialF-61E79SRT10 C000709088376000CarcinogenC-29000SRT11 C0085393370388006Patient immunocompromisedF-00D5FSRT12 C0003069Transgenic animalC0003069UMLS

13 CID sex01 Sex - Male Female or Both



18 Table CID sex01. Sex - Male Female or Both

19 UMLS Concept Unique20 ID

SNOMED-CT ConceptID

Code MeaningCode ValueCoding Scheme Designator

21 MaleMDCM22 FemaleFDCM23 Mixed sexddd146DCM

24 CID rom01 Animal Room Types



29 Table CID rom01. Animal Room Types

30 UMLS Concept31 Unique ID

SNOMED-CT ConceptID


32 Animal housing roomddd370DCM33 Preparation roomddd371DCM34 Imaging procedure roomddd372DCM35 C1532289414485004Induction roomR-305D6SRT36 C0198828398161000Recovery roomR-305C3SRT37 C1443994409688003Isolation roomR-305D3SRT

38 Note

39 1. Only rooms appropriate for animals in the context of in vivo imaging are described (e.g., not necropsy rooms, etc.)

40 2. (R-305C3, SRT, "Recovery room" (synonym of "postoperative anesthesia care unit ") is reused here even though its41 parent is "Location within hospital premises (environment)", which is arguably specifically human. The same is true for42 (R-305D6, SRT, "Induction room") and (R-305D3, SRT, "Isolation room").

43 - Draft -


1 CID dsp01 Device Reuse

2 Type:3 Extensible


6 Table CID dsp01. Device Reuse


SNOMED-CT ConceptID


9 Unusedddd177DCM10 Reusedddd178DCM

11 CID bed01 Animal Bedding Material



16 Table CID bed01. Animal Bedding Material


SNOMED-CTConcept ID


19 Aspen chip beddingddd230DCM20 Aspen shaving beddingddd231DCM21 Corn cob beddingddd232DCM22 Paper-based beddingddd233DCM23 Pine chip beddingddd234DCM24 Pine shaving beddingddd235DCM

25 CID she01 Animal Shelter Types



30 Table CID she01. Animal Shelter Types


SNOMED-CT ConceptID


33 C0549184260413007NoneR-40775SRT34 Iglooddd220DCM35 Red translucent iglooddd221DCM

36 CID fed01 Animal Feed Types



41 - Draft -


1 Table CID fed01. Animal Feed Types


SNOMED-CTConcept ID


4 NIH07ddd271DCM5 NIH31ddd270DCM6 AIN76ddd272DCM7 AIN93Gddd273DCM8 AIN93Mddd274DCM

9 Note

10 This context group includes the open source diets described in Barnard DE et al. Open- and Closed-Formula Laboratory11 Animal Diets and Their Importance to Research. Journal of the American Association for Laboratory Animal Science : JAALAS12 (2009), 48(6), 709–713. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786923/.

13 A more extensive list of NIH-specified diets for small animals (not just mice and rats) can be found at https://web.archive.org/14 web/20100527090853/http://dvrnet.ors.od.nih.gov/diets_info.asp.

15 CID fed02 Animal Feed Sources



20 Table CID fed02. Animal Feed Sources


SNOMED-CTConcept ID


23 Commercial productC1547887UMLS24 Locally manufactured productddd390DCM

25 Note

26 (C1547887, UMLS, "Commercial product") originates from the HL7 V2.5 Chapter 04 blood products description as an attribute27 name rather than a value, but in UMLS is not expressly constrained and has as a parent generic semantic type of "Manufac-28 tured Object".

29 CID fed03 Animal Feeding Methods



34 Table CID fed03. Animal Feeding Methods

35 UMLS Concept Unique IDSNOMED-CT36 Concept ID


37 C1879743ad libitumC64636NCIt38 C0425422Restricted dietC0425422UMLS39 Food treatddd391DCM40 C004128161420007GavagePA-00620SRT

41 - Draft -


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786923/

https://web.archive.org/web/20100527090853/http://dvrnet.ors.od.nih.gov/diets_info.asp

https://web.archive.org/web/20100527090853/http://dvrnet.ors.od.nih.gov/diets_info.asp

1 Note

2 (C0425422, UMLS, "Restricted diet") corresponds to the inactive SNOMED concept of "Dietary restriction NOS"; SNOMED3 currently does not seem to have an active generic concept of a restricted diet, as opposed to many specific types of restricted4 diet. In this context, the intent is to convey that the diet is controlled and restricted to finite quantities (e.g., as opposed to ad5 libitum) without requiring a detailed classification of what components are restricted.

6 CID wat01 Water Types

7 Type:8 Extensible


11 Table CID wat01. Water Types


SNOMED-CT ConceptID


14 C2919405444923006Tap waterC-101E9SRT15 C0790233444883009Distilled waterC-101E8SRT16 Reverse osmosis purified waterddd290DCM17 Reverse osmosis purified, HCl18 acidified water

ddd291DCM

19 CID ans01 Anesthesia Category Code Type for Small Animal Anesthesia



24 Table CID ans01. Anesthesia Category Code Type for Small Animal Anesthesia

25 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme26 Designator27 Include CID aqi01 “Anesthesia Category Code Type from Anesthesia Quality Initiative (AQI)”

28 CID aqi01 Anesthesia Category Code Type from Anesthesia Quality Initiative (AQI)



33 Table CID aqi01. Anesthesia Category Code Type from Anesthesia Quality Initiative (AQI)


SNOMED-CT Concept IDCode MeaningCode ValueCoding SchemeDesignator

36 C000291550697003General anesthesiaP1-C0010SRT37 C034410672641008SedationP1-C0B00SRT38 C0002928231249005Spinal anesthesiaP1-C0208SRT39 C000291318946005Epidural anesthesiaP1-C0220SRT40 C000291127372005Regional anesthesiaP1-C0200SRT41 C0472473386760001Topical local anesthesiaP1-C0037SRT42 C0002921386761002Local anesthesiaP1-C0038SRT43 C1301902398239001Monitored Anesthesia Care44 (MAC)

P1-0512ESRT

45 - Draft -


1 Note

2 This context group contains SNOMED procedure code equivalents of enumerated string concepts for the AQI schema element3 AnesthesiaCategoryCodeType. See http://www.aqihq.org/aqischdoc/AnesthesiaCategoryCodeType.html. Used by permission4 of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).

5 CID ans02 Anesthesia Induction Code Type for Small Animal Anesthesia

6 Type:7 Extensible


10 Table CID ans02. Anesthesia Induction Code Type for Small Animal Anesthesia

11 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme12 Designator13 Include CID aqi02 “Anesthesia Induction Code Type from Anesthesia Quality Initiative (AQI)”

14 C152258338239002Intraperitoneal routeG-D106SRT

15 Note

16 The intraperitoneal route is added to the AQI value set, since that route is used for small animal imaging.

17 CID aqi02 Anesthesia Induction Code Type from Anesthesia Quality Initiative (AQI)



22 Table CID aqi02. Anesthesia Induction Code Type from Anesthesia Quality Initiative (AQI)

23 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme24 Designator25 C0205535112239003By inhalationG-D150SRT26 C152272647625008Intravenous routeG-D101SRT27 C152742537161004Per rectumG-D160SRT28 C155615478421000Intramuscular routeG-D103SRT

29 Note

30 This context group contains SNOMED administration route code equivalents of enumerated string concepts for the AQI31 schema element AnesthesiaInductionCodeType. See http://www.aqihq.org/aqischdoc/AnesthesiaInductionCodeType.html.32 Used by permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).

33 CID ans03 Anesthesia Maintenance Code Type for Small Animal Anesthesia



38 Table CID ans03. Anesthesia Maintenance Code Type for Small Animal Anesthesia

39 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme40 Designator41 Include CID aqi03 “Anesthesia Maintenance Code Type from Anesthesia Quality Initiative (AQI)”

42 - Draft -


http://www.aqihq.org/aqischdoc/AnesthesiaCategoryCodeType.html

http://aqihq.org/

http://www.aqihq.org/aqischdoc/AnesthesiaInductionCodeType.html

http://aqihq.org/

1 CID aqi03 Anesthesia Maintenance Code Type from Anesthesia Quality Initiative (AQI)

2 Type:3 Extensible


6 Table CID aqi03. Anesthesia Maintenance Code Type from Anesthesia Quality Initiative (AQI)


SNOMED-CT ConceptID


9 C0198795112987001Inhalation anesthesia, machine system,10 closed, rebreathing of primary agent

P1-C0020SRT

11 C019879644812007Inhalation anesthesia, machine system,12 closed, no rebreathing of primary agent

P1-C0030SRT

13 Note

14 This context group contains SNOMED procedure code equivalents of enumerated string concepts for the AQI schema element15 AnesthesiaMaintenanceCodeType. See http://www.aqihq.org/aqischdoc/AnesthesiaMaintenanceCodeType.html. Used by16 permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).

17 The AQI value "circle system" corresponds to (P1-C0020, SRT, "Inhalation anesthesia, machine system, closed, rebreathing18 of primary agent").

19 The AQI value "non-rebreathing" corresponds to (P1-C0030, SRT, "Inhalation anesthesia, machine system, closed, no20 rebreathing of primary agent").

21 CID ans04 Airway Management Method Code Type for Small Animal Anesthesia



26 Table CID ans04. Airway Management Method Code Type for Small Animal Anesthesia


SNOMED-CT ConceptID


29 Include CID aqi04 “Airway Management Method Code Type from Anesthesia Quality Initiative (AQI)”

30 Nose coneddd060DCM

31 CID aqi04 Airway Management Method Code Type from Anesthesia Quality Initiative (AQI)



36 Table CID aqi04. Airway Management Method Code Type from Anesthesia Quality Initiative (AQI)


SNOMED-CT ConceptID


39 C0419011243147009Controlled VentilationP2-2290DSRT40 C003520540617009Artificial RespirationP2-22902SRT41 C018463357485005Oxygen TherapyP2-22500SRT42 C0396618424979004Laryngeal Mask Airway (LMA)P0-05DE2SRT43 C3164350447996002Intubation of respiratory tractP0-06211SRT44 C0573976297120004Anesthetic face maskA-00BA2SRT

45 - Draft -


http://www.aqihq.org/aqischdoc/AnesthesiaMaintenanceCodeType.html

http://aqihq.org/


SNOMED-CT ConceptID


3 C0573976297120004Anesthetic face maskA-00BA2SRT4 C0179574Nasal cannuladdd061DCM5 C0393370180640008Via tracheostomyG-D13ESRT

6 Note

7 This context group contains SNOMED procedure or physical object or qualifier value code equivalents of enumerated string8 concepts for the AQI schema element AirwayManagementMethodCodeType. See http://www.aqihq.org/aqischdoc/9 AirwayManagementMethodCodeType.html. Used by permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).

10 CID ans05 Airway Management Sub-Method Code Type for Small Animal Anesthesia



15 Table CID ans05. Airway Management Sub-Method Code Type for Small Animal Anesthesia

16 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme17 Designator18 Include CID aqi05 “Airway Management Sub-Method Code Type from Anesthesia Quality Initiative (AQI)”

19 CID aqi05 Airway Management Sub-Method Code Type from Anesthesia Quality Initiative20 (AQI)



25 Table CID aqi05. Airway Management Sub-Method Code Type from Anesthesia Quality Initiative (AQI)


SNOMED-CT ConceptID


28 C2223982Inverse ratio ventilationC2223982UMLS29 C0019540243154003High frequency ventilationP2-22914SRT30 C3164603448442005Transtracheal jet ventilationP2-22933SRT31 C0419018243156001Continuous flow ventilationP2-22916SRT

32 Note

33 This context group contains SNOMED procedure code equivalents of enumerated string concepts for the AQI schema element34 AirwayManagementSubMethodCodeType. See http://www.aqihq.org/aqischdoc/AirwayManagementSubMethodCodeType.html.35 Used by permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).

36 CID ans06 Medication Type Code Type for Small Animal Anesthesia



41 - Draft -


http://www.aqihq.org/aqischdoc/AirwayManagementMethodCodeType.html


http://aqihq.org/

http://www.aqihq.org/aqischdoc/AirwayManagementSubMethodCodeType.html

http://aqihq.org/

1 Table CID ans06. Medication Type Code Type for Small Animal Anesthesia


SNOMED-CT ConceptID


4 Include CID aqi06 “Medication Type Code Type from Anesthesia Quality Initiative (AQI)”

5 Carrier gasddd330DCM

6 CID aqi06 Medication Type Code Type from Anesthesia Quality Initiative (AQI)

7 Type:8 Extensible


11 Table CID aqi06. Medication Type Code Type from Anesthesia Quality Initiative (AQI)



14 C000255614443002Aminoglycoside antibioticC-52500SRT15 C0026458373297006Beta-Lactam antibioticC-00231SRT16 C0006968396345004Carbapenem antibioticC-002B1SRT17 C3536856373262009Cephalosporin antibioticC-0021CSRT18 C0663241387056004Linezolid antibioticC-00286SRT19 C0023726372677003Lincomycin antibioticC-0023BSRT20 C0003240372480009Macrolide antibioticC-00211SRT21 C0025872372602008Metronidazole antibioticF-616FESRT22 C0003232255631004AntibioticC-5008CSRT23 C0030842373270004Penicillin antibioticC-0021DSRT24 C1533693372722000Quinolone antibioticC-0024CSRT25 C0599503372788003Sulfonamide antibioticC-00257SRT26 C1744619373206009Tetracycline antibioticC-00216SRT27 C0042313372735009Vancomycin antibioticC-0024ESRT28 C000163786308005Adrenergic agentC-68000SRT29 C0304463372795007Alkalinizing agentF-6195ESRT30 C0002771373265006AnalgesicF-6181FSRT31 C0017302373288007General anestheticF-6186ASRT32 C0002934373477003Local anestheticF-6183DSRT33 C170548077671006Antidiuretic hormoneF-B1810SRT34 C0003195372813008AntiarrhythmicF-6196ESRT35 C0242896373246003AnticholinergicF-6180BSRT36 C0003280372862008AnticoagulantF-6199ASRT37 C0003286255632006AnticonvulsantR-F1216SRT38 C0360298372906009Benzodiazepine antagonistF-619EFSRT39 C0304941372708000Anti-heparin agentF-618BASRT40 C0003297372764000AntiemeticF-61943SRT41 C0003308373219008AntifungalF-617EFSRT42 C0003360372806008AntihistamineF-61969SRT43 C00033641182007AntihypertensiveC-81100SRT

44 - Draft -




3 C1579431AntihypoglycemicC1579431UMLS4 C0003286255632006AnticonvulsantR-F1216SRT5 C0004745372798009BarbiturateR-F2B23SRT6 C0005064372664007BenzodiazepineR-F2B1DSRT7 C0001645373254001Beta-blockerF-61814SRT8 C0456388410652009Blood productR-005B3SRT9 C0006280372580007BronchodilatorF-616EBSRT10 C00066755540006CalciumC-14300SRT11 C0006684373304005Calcium channel blockerF-61878SRT12 C0280082373530005Caloric agentF-618D8SRT13 C1720711421148003Cholinergic agentF-620E8SRT14 C0242896373246003Anticholinergic agentF-6180BSRT15 C030422174626007Drug diluentC-50013SRT16 C0012798372695000DiureticF-618AFSRT17 C001493941598000EstrogenF-B2700SRT18 C1268865373461004Gastrointestinal prokineticF-6182CSRT19 C0019593H2 antagonistC0019593UMLS20 C0019120372681003Hemostatic agentF-618A5SRT21 C0020616373299009HypoglycemicF-61873SRT22 C0304509111139005Inotropic agentC-80120SRT23 C0019139373294004Low Molecular Weight HeparinF-6186FSRT24 C002446772717003MagnesiumC-14800SRT25 C0027409Narcotic analgesicC0027409UMLS26 C0027410372656001Narcotic (opiate) antagonistF-6188FSRT27 C004239896329004Nasal decongestantC-97302SRT28 C0027867373250005NeuroMuscular Blocking (NMB)29 - depolarizing

F-6180FSRT

30 C0304435372790002NeuroMuscular Blocking (NMB)31 - non depolarizing

F-61959SRT

32 C0003211372665008NSAIDF-61898SRT33 C0717951398828005Ocular LubricantF-61D70SRT34 C0030094410937004OxytocicF-61E2ASRT35 C1268852372578001Plasma ExpanderF-616E7SRT36 C003282188480006PotassiumC-13500SRT37 C0282685418760000Respiratory stimulantF-6205DSRT38 C0037250372666009Skeletal muscle relaxantF-61899SRT39 C0038317116566001SteroidC-10098SRT40 C004013518220004Thyroid hormoneF-B3000SRT41 C0042402372787008VasodilatorF-61957SRT42 C0042397372881000VasoconstrictorF-619AASRT43 C004289087708000VitaminF-BB000SRT

44 - Draft -


1 Note

2 This context group contains SNOMED substance or product code equivalents of enumerated string concepts for the AQI3 schema element MedicationTypeCodeType. See http://www.aqihq.org/aqischdoc/MedicationTypeCodeType.html. Used by4 permission of the Anesthesia Quality Institute (AQI) (http://aqihq.org/).

5 The AQI value "ABX-Miscellaneous" corresponds to (C-5008C, SRT, "Antibiotic") product, since there is no substance code6 in SNOMED.

7 The AQI value "Vasopressor" corresponds to (F-619AA, SRT, "Vasoconstrictor").

8 No equivalent concepts are included for MedicationTypeCodeType values of NonFormulary antibiotic, Dye, Indigo Carmine9 Red, and Non-Formulary.

10 CID ans07 Medication for Small Animal Anesthesia



15 Table CID ans07. Medication for Small Animal Anesthesia



18 Include CID ans08 “Inhalational Anesthesia Agents for Small Animal Anesthesia”

19 Include CID ans09 “Injectable Anesthesia Agents for Small Animal Anesthesia”

20 Include CID ans09b “Premedication Agents for Small Animal Anesthesia”

21 Include CID ans10 “Neuromuscular Blocking Agents for Small Animal Anesthesia”

22 Include CID ans11 “Ancillary Medications for Small Animal Anesthesia”

23 Include CID ans11b “Carrier Gases for Small Animal Anesthesia”

24 Include CID ans11c “Local Anesthetics for Small Animal Anesthesia”

25 CID ans08 Inhalational Anesthesia Agents for Small Animal Anesthesia



30 Table CID ans08. Inhalational Anesthesia Agents for Small Animal Anesthesia

31 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme32 Designator33 C000701231811003Carbon dioxideC-10520SRT34 C0008238259153006ChloroformC-20830SRT35 C0063252386841003DesfluraneF-61AC9SRT36 C0014994259170003Diethyl etherC-21216SRT37 C0014277387176008EnfluraneF-61A3FSRT38 C0018549387351001HalothaneF-61AFESRT39 C0022180387368002IsofluraneF-61B0ASRT40 C002568811136004MethoxyfluraneC-6A16ASRT41 C0028215111132001Nitrous oxideC-6A118SRT42 C0074414386842005SevofluraneF-61ACASRT

43 - Draft -


http://www.aqihq.org/aqischdoc/MedicationTypeCodeType.html

http://aqihq.org/

1 Note

2 In this context group, SNOMED substance codes are used in preference to product codes, since there is no need to refer3 to specific products or preparations. SNOMED codes are used in preference to other potential sources of pharmaceutical4 related codes, such as from the National Drug Code (NDC) directory.

5 CID ans09 Injectable Anesthesia Agents for Small Animal Anesthesia

6 Type:7 Extensible


10 Table CID ans09. Injectable Anesthesia Agents for Small Animal Anesthesia

11 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme12 Designator13 C0008162277016007AlphachloraloseC-23805SRT14 C0051481125707004AlphadoloneC-6A161SRT15 C0051482AlphaxaloneC0051482UMLS16 C000447796229001AzaperoneC-640A0SRT17 C0006464372901004ButabarbitalR-F2B27SRT18 C0008161273948005Chloral hydrateR-F6E36SRT19 C0012010387264003DiazepamR-F2B2CSRT20 C0013136387146001DroperidolF-61A26SRT21 C0015131387218008EtomidateF-61A66SRT22 C0060473FluanisoneC0060473UMLS23 C0022614373464007KetamineF-6182FSRT24 C0025668373488009MethohexitalF-61848SRT25 C0025856MetomidateC0025856UMLS26 C0026056373476007MidazolamF-6183CSRT27 C0030883372703009PentobarbitalR-F2B1FSRT28 C0033487387423006PropofolF-61B48SRT29 C003985540342009ThiamylalC-6A16BSRT30 C0936073387448009ThiopentalF-61BB2SRT31 C024252296265006TiletamineC-6A190SRT32 C008484784386009TribromoethanolC-6A16ESRT33 C004196472545006Urethane (ethyl carbamate)C-21805SRT34 C024254496230006XylazineC-640B0SRT35 C091785996227004ZolazepamC-64090SRT

36 Note


40 CID ans09b Premedication Agents for Small Animal Anesthesia



45 - Draft -


1 Table CID ans09b. Premedication Agents for Small Animal Anesthesia

2 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme3 Designator4 C000095996218000AcepromazineC-62960SRT5 C0008286387258005ChlorpromazineF-61A7FSRT

6 CID ans10 Neuromuscular Blocking Agents for Small Animal Anesthesia

7 Type:8 Extensible


11 Table CID ans10. Neuromuscular Blocking Agents for Small Animal Anesthesia

12 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme13 Designator14 C0038627372724004SuccinylcholineF-61916SRT15 C0030310373738000PancuroniumF-61639SRT

16 Note


20 CID ans11 Ancillary Medications for Small Animal Anesthesia



25 Table CID ans11. Ancillary Medications for Small Animal Anesthesia

26 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme Designator

27 Note


31 CID ans11b Carrier Gases for Small Animal Anesthesia



36 Table CID ans11b. Carrier Gases for Small Animal Anesthesia

37 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme38 Designator39 C0350411320917000Oxygen gasC-6A102SRT40 C3536832417696007Medical airC-6A148SRT41 C3846005Room airC3846005UMLS

42 - Draft -


1 Note

2 In this context group, though SNOMED substance codes are normally used in preference to product codes, in the case of3 (C-6A102, SRT, "Oxygen gas") there is no corresponding substance that is specifically the gaseous form of oxygen.

4 CID ans11c Local Anesthetics for Small Animal Anesthesia

5 Type:6 Extensible


9 Table CID ans11c. Local Anesthetics for Small Animal Anesthesia

10 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme11 Designator12 C0006400387150008BupivacaineF-61A28SRT13 C0617623346553009Lidocaine + PrilocaineC-80477SRT14 C0023660387480006LidocaineF-61BD0SRT

15 Note

16 • In this context group, SNOMED substance codes are used in preference to product codes, since there is no need to refer17 to specific products or preparations. SNOMED codes are used in preference to other potential sources of pharmaceutical18 related codes, such as from the National Drug Code (NDC) directory.

19 • For Lidocaine + Prilocaine, since it is a mixture of two substances, the code for the product concept is used. The code for20 a mixture of unspecified type is used, rather than a more specific code, e.g., for the so-called "Eutectic Mixture of Local21 Anesthetics (EMLA)", which consists of Lidocaine + Prilocaine. UMLS contains three distinct concepts, (C0059079, UMSL,22 "EMLA"), (C0617623, UMLS, "Lidocaine/Prilocaine") and (C0950567, UMLS, "Eutectic Lidocaine-Prilocaine").

23 CID ans12 Phase of Procedure Requiring Anesthesia



28 Table CID ans12. Phase of Procedure Requiring Anesthesia

29 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme30 Designator31 Include CID ans13 “Phase of Surgical Procedure Requiring Anesthesia”

32 Include CID ans14 “Phase of Imaging Procedure Requiring Anesthesia”

33 Note

34 CID ans13 Phase of Surgical Procedure Requiring Anesthesia



39 Table CID ans13. Phase of Surgical Procedure Requiring Anesthesia

40 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme41 Designator42 C0445204262068006PreoperativeR-413C5SRT43 C0456904277671009IntraoperativeR-400B2SRT

44 - Draft -


1 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme2 Designator3 C0032790262061000PostoperativeR-413B7SRT

4 Note

5 CID ans14 Phase of Imaging Procedure Requiring Anesthesia

6 Type:7 Extensible


10 Table CID ans14. Phase of Imaging Procedure Requiring Anesthesia

11 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme12 Designator13 C0585032307153007Before procedureR-40FB9SRT14 C0585033307154001During procedureR-40FBASRT15 C0580203303110006After procedureR-422A4SRT

16 Note

17 The concepts used in this context group are more general than those for a specific procedure, e.g., surgery, radiotherapy,18 chemotherapy. In SNOMED, the concepts used in this context group are the parent concepts of the surgically-specific concepts19 used in CID ans12 “Phase of Procedure Requiring Anesthesia”. There are no concepts defined specifically for periods related20 to an imaging procedure so the general concepts suffice (in context).

21 CID pha01 Phase of Animal Handling



26 Table CID pha01. Phase of Animal Handling


SNOMED-CTConcept ID


29 In home cageddd101DCM30 During transportddd102DCM31 Staging prior to imagingddd103DCM32 Preparation for imagingddd104DCM33 C0473960241687005Anesthesia inductionP1-C0012SRT34 C0011923363679005Imaging procedureP0-0099ASRT35 C0002908Anesthesia recovery periodC0002908UMLS

36 Note

37 CID hea01 Heating Method



42 - Draft -


1 Table CID hea. Heating Method


SNOMED-CTConcept ID


4 468192005Air heating padR-FDB79SRT5 C033661479811009Electric blanketA-18041SRT6 C018115727812008Electric heating padA-2C140SRT7 Forced air heaterddd250DCM8 C1719899420572009Forced air warming blanketA-17454SRT9 Heated imaging deviceddd251DCM10 Heated patient supportddd252DCM11 Heated water blanketddd253DCM12 C0181514Heat lampC0181514UMLS13 C052120039790008Non-electric heating padA-2C141SRT14 Pre-heated padddd254DCM15 Unheatedddd255DCM16 C018434871384000Warmer deviceA-17450SRT17 C0184351421335007Warming blanketA-17452SRT

18 Note

19 CID hea02 Temperature Sensor Device Component Type for Small Animal Procedures



24 Table CID hea02. Temperature Sensor Device Component Type for Small Animal Procedures


SNOMED-CT ConceptID


27 C0489749307047009Rectal temperatureF-00BB8SRT28 C0039810ThermographyC0039810UMLS29 Carrier temperature sensorddd240DCM

30 Note

31 (C0039810, UMLS, "Thermography") is a general concept that also encompasses diagnostic uses of thermography, in addition32 to simple temperature measurement; only the latter meaning is used here, as is implicit from the context of invocation.

33 CID exo01 Exogenous Substance Types



38 Table CID exo01. Exogenous Substance Types

39 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme40 Designator41 C0181074246345001Graft materialG-C1F9SRT42 Tumor Graftddd460DCM

43 - Draft -


1 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme2 Designator3 C022532888921000FibrilT-1A080SRT4 C004277649872002VirusL-30000SRT5 C007918975777003CytokineF-CB250SRT6 C004054980917008ToxinC-00224SRT

7 Note

8 The specific concept (C22490, NCIt, "Tumor Cell Graft") (UMLS:C1519674) is not used, since grafts may not be cell suspen-9 sions, but rather entire tumors, fragments of tumor tissue, etc. Whether the graft is a xenograft or homograft is not specified,10 and may be encoded elsewhere (e.g., by encoding the species of origin). The non-tumor specific concept (G-C1F9, SRT,11 "Graft material") may be used when the graft is not a tumor (though strictly speaking, it is a SNOMED attribute rather than12 substance; UMLS:C0181074 does not make such a distinction).

13 CID exo05 Exogenous Substance



18 Table CID exo05. Exogenous Substance

19 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme20 Designator21 Include CID exo10 “Tumor Graft Histologic Type”

22 Include CID exo11 “Fibrils”

23 Include CID exo12 “Viruses”

24 Include CID exo13 “Cytokines”

25 Include CID exo14 “Toxins”

26 Note

27 CID exo10 Tumor Graft Histologic Type

28 Type:29 Extensible30 Version:31 yyyymmdd

32 Table CID exo10. Tumor Graft Histologic Type


SNOMED-CT ConceptID


35 C000141835917007AdenocarcinomaM-81403SRT36 C020673570594002Amelanotic melanomaM-87303SRT37 C000411438713004AstrocytomaM-94003SRT38 C0007120Bronchioloalveolar39 adenocarcinoma

C2923NCIt

40 C000709768453008CarcinomaM-80103SRT41 C000714063264007CarcinosarcomaM-89803SRT42 C001063121008007CystadenocarcinomaM-84403SRT43 C001763663634009GlioblastomaM-94403SRT

44 - Draft -



SNOMED-CT ConceptID


3 C1134719408643008Infiltrating ductal carcinoma of4 breast

D0-F0369SRT

5 C020670422687000Large cell carcinomaM-80123SRT6 C002341893143009LeukemiaDC-F4113SRT7 C00252022092003MelanomaM-87203SRT8 C002550062064005MesotheliomaM-90503SRT9 C033424021326004Mixed small cell carcinomaM-80453SRT10 C1266002128632008Non-small cell carcinomaM-80463SRT11 C002946321708004OsteosarcomaM-91803SRT12 C0007134702391001Renal cell carcinomaR-FB83FSRT13 C12614732424003SarcomaM-88003SRT14 C026258474364000Small cell carcinomaM-80413SRT15 C020569765692009Spindle cell carcinomaM-80323SRT16 C000713728899001Squamous cell carcinomaM-80703SRT

17 CID exo11 Fibrils


22 Table CID exo11. Fibrils


SNOMED-CTConcept ID


25 Human alpha synuclein preformed fibrils26 Mouse alpha synuclein preformed fibrils27 Human Tau preformed fibrils28 Mouse Tau preformed fibrils

29 CID exo12 Viruses


34 Table CID exo12. Viruses


SNOMED-CT ConceptID


37 Theiler's murine encephalomyelitis virus38 Adeno-associated viral vectors

39 CID exo13 Cytokines


44 - Draft -


1 Table CID exo13. Cytokines


SNOMED-CT ConceptID


4 Tumor necrosis factor alpha5 Interferon gamma6 Vascular endothelial growth factor

7 CID exo14 Toxins


12 Table CID exo14. Toxins


SNOMED-CT ConceptID


15 Lysophosphatidylcholine16 Ethidium Bromide17 6-hydroxydopamine18 Lipopolysaccharide

19 CID exo30 Exogenous Substance Administration Sites


24 Table CID exo30. Exogenous Substance Administration Sites

25 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme26 Designator27 C023017158602004FlankT-D2310SRT28 C000610412738006BrainT-A0100SRT29 C0027651108369006TumorM-8FFFFSRT

30 Note

31 Since this context group defines the sites, rather than routes of administration, if the exogenous usbstance is administered32 into a tumor, the code for the morphoogic abnormality (M-8FFFF, SRT, "Tumor") is used, rather than the specific concept33 for the route (R-F2CD4, SRT, "Intratumor route") (which may also be present as the value for the separately encoded route34 of administration, if present).

35 CID exo50 Exogenous Substance Tissue of Origin


40 Table CID exo50. Exogenous Substance Tissue of Origin

41 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme42 Designator43 C0003964409615008Ascitic fluidT-D04ACSRT44 C0262950272673000BoneT-D016ESRT45 C000610412738006BrainT-A0100SRT

46 - Draft -


1 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme2 Designator3 C000614176752008BreastT-04000SRT4 C092723221483005Central nervous systemT-A0090SRT5 C000936871854001ColonT-59300SRT6 Embryonic kidneyDCM_ddd801DCM7 C002264664033007KidneyT-71000SRT8 C002410939607008LungT-28000SRT9 C002420238000004LymphT-C6020SRT10 C0024296181768009Lymphatic tissueT-D03C2SRT11 C002420459441001Lymph NodeT-C4000SRT12 C2939419128462008MetastasisDF-00436SRT13 C002993915497006OvaryT-87000SRT14 C003222760046008Pleural effusionD2-80100SRT15 C1278980181422007ProstateT-9200BSRT16 C015367694391008Pulmonary metastasisD2-F1106SRT

17 CID proc01 Preclinical Small Animal Imaging Procedures



22 Table CID proc01. Preclinical Small Animal Imaging Procedures



25 C1830206Whole body CT46305-9LN26 C0202691303653007Head CT24725-4LN27 C1830259426252008MRI whole body46358-8LN28 Brain MRI24590-2LN29 C1715409702767007PET whole body44139-4LN30 C0412493241434002Brain PET44138-6LN31 C1626178229033006Radionuclide scan of whole body42175-0LN32 C058158241440006Radionuclide brain scan24730-4LN33 859201000000109SPECT of whole bodyNBODWNICIP34 C1543694Brain SPECT39632-5LN35 859221000000100SPECT CT of whole bodyNCBDWNICIP36 C020330924135002Ultrasonography of total bodyP5-B0008SRT

37 Note

38 1. The inconsistent pattern of modality and anatomy in the code meaning is present in the original coding scheme (e.g.,39 "Whole body CT" versus "PET whole body"), and not changed, except where necessary (e.g., LN:42175-0 is actually40 just "scan of whole body" in the original, which is insufficient, so "radionuclide" has been added).

41 2. The SNOMED codes for SPECT (+/- CT) of whole body are from the UK National Extension and are not present in the42 current SNOMED International release.

43 - Draft -











1 3. The UMLS codes that map to the SNOMED concepts, when present, are shown, in the cases when UMLS is lacking a2 mapping between the LOINC and SNOMED codes. E.g., (44138-6, LN, "Brain PET") maps directly to (C1715408, UMLS,3 "Multisection:Find:Pt:Brain:Doc:Radnuc.PET"), but (241434002, SCT, "PET Brain Study") maps to (C0412493, UMLS,4 "PET Brain Study"), which is used instead. In general, UMLS does not unify the mappings from LOINC and SNOMED,5 presumably due to the lexical dissimilarity of the terms (i.e., the LOINC mapping seems to be based on the fully-specified6 name rather than the long common name).

7 CID pri Position Reference Indicator for Frame of Reference

8 Type:9 Extensible


12 Table CID pri. Position Reference Indicator for Frame of Reference

13 UMLS Concept Unique IDSNOMED-CT14 Concept ID


15 C0934419Bregma264776FMA16 C0926407Lambda264773FMA

17 Note

18 An FMA code is used for bregma since SNOMED only contains fetal bregma.

19 Amend existing context groups in DICOM PS3.16 to add additional concepts:

20 CID 11 Route of Administration

21 Type:22 Extensible23 Version:24 20100608 yyyymmdd

25 Table CID 11. Route of Administration



28 C152272647625008Intravenous routeG-D101SRT29 C156145158100008Intra-arterial routeG-D102SRT30 C155615478421000Intramuscular routeG-D103SRT31 C152243834206005Subcutaneous routeG-D104SRT32 C152247559593002Intracutaneous routeG-D105SRT33 C152258338239002Intraperitoneal routeG-D106SRT34 C151295760213007Intramedullary routeG-D107SRT35 C067789772607000Intrathecal routeG-D108SRT36 C020552812130007Intra-articular routeG-D109SRT37 C151294389947002Intraepithelial routeG-D111SRT38 C15221686064005Topical routeG-D112SRT39 C152741526643006Oral routeG-D140SRT40 C02055329942002Transluminal routeG-D142SRT41 C152221737737002Intraluminal routeG-D144SRT42 C020553431638007Extraluminal routeG-D146SRT43 C0205535112239003By inhalationG-D150SRT44 C152742537161004Per rectumG-D160SRT

45 - Draft -


http://fme.biostr.washington.edu/FME/index.jsp?fmaid=264776

http://fme.biostr.washington.edu/FME/index.jsp?fmaid=264773



3 C152257016857009Vaginal routeG-D164SRT4 C0595454372463005Intracoronary routeG-D17CSRT5 C1522207372460008Intracardiac routeG-D173SRT6 C1720462420287000Intraventricular route - cardiacR-F2C86SRT7 Retro-orbital routeddd070DCM8 C152201946713006Nasal routeG-D172SRT9 C1522475372464004Intradermal routeG-D17DSRT10 C2960749447122006Intratumor routeR-F2CD4SRT

11 For reference (unchanged) and to allow the hypertext links to work, existing relevant context groups in DICOM PS3.16:

12 CID 100 Quantitative Diagnostic Imaging Procedures


15 Version:16 20141110

17 Table CID 100. Quantitative Diagnostic Imaging Procedures


SNOMED-CTConcept ID


20 C0442974258177008Magnetic resonance imaging guidanceP5-09051SRT21 Multiparametric MRI126020DCM22 Multiparametric MRI of prostate126021DCM23 Multiparametric MRI of whole body126022DCM24 C2315346433139009Dynamic magnetic resonance imaging of25 knee

P5-0907FSRT

26 C2960816446315002Dynamic magnetic resonance imaging of27 pelvis

P5-70694SRT

28 C1715409PET whole body44139-4LN29 C2732676443271005PET/CT FDG imaging of whole bodyP5-080FFSRT30 C2732956443844003PET/CT MET imaging of whole bodyP5-08118SRT31 CT HEAD PERFUSION WITH IV32 CONTRAST

RPID96RADLEX

33 NM HEAD PERFUSION BRAIN SPECTRPID5258RADLEX34 NM HEAD PERFUSION BRAIN PET-CT35 AV-45

RPID5427RADLEX

36 CID 230 Yes-No

37 Type:38 Non-Extensible39 Version:40 20060613

41 Table CID 230. Yes-No

42 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme43 Designator44 C1298907373066001YesR-0038DSRT

45 - Draft -


1 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme2 Designator3 C1298908373067005NoR-00339SRT4 C3536725373068000UndeterminedR-0038ASRT

5 CID 244 Laterality

6 Type:7 Non-Extensible8 Version:9 20030108

10 Table CID 244. Laterality

11 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme12 Designator13 C020509024028007RightG-A100SRT14 C02050917771000LeftG-A101SRT15 C023876751440002Right and leftG-A102SRT16 C020509266459002UnilateralG-A103SRT

17 CID 6092 Quantitative Concepts for Usage, Exposure

18 Type:19 Extensible20 Version:21 20040112

22 Table CID 6092. Quantitative Concepts for Usage, Exposure


SNOMED-CT ConceptID


25 C0178602260911001DosageG-C0B7SRT26 Dose frequency111578DCM27 Rate of exposure111579DCM28 Volume of use111580DCM

29 CID 6046 Units of Follow-up Interval


34 Table CID 6046. Units of Follow-up Interval


SNOMED-CT ConceptID


37 daydUCUM38 weekwkUCUM39 monthmoUCUM40 yearaUCUM

41 CID 6090 Relative Usage, Exposure Amount


46 - Draft -


1 Table CID 6090. Relative Usage, Exposure Amount


SNOMED-CTConcept ID


4 High111575DCM5 Medium111576DCM6 Low111577DCM7 No known exposure111587DCM

8 CID 6091 Relative Frequency of Event Values


13 Table CID 6091. Relative Frequency of Event Values

14 UMLS Concept Unique IDSNOMED-CT Concept IDCode MeaningCode ValueCoding Scheme15 Designator16 C0549178255238004ContinuousR-40377SRT17 C033218370232002FrequentG-7154SRT18 C0439604255218000Mid-frequencyR-40365SRT19 C052111427789000InfrequentG-7155SRT20 C0558288225761000As requiredR-40B16SRT21 C0585347307486002Single eventR-4112FSRT

22 CID 6093 Qualitative Concepts for Usage, Exposure Amount


27 Table CID 6093. Qualitative Concepts for Usage, Exposure Amount


SNOMED-CTConcept ID


30 Relative dose amount111581DCM31 Relative amount of exposure111582DCM32 Relative amount of use111583DCM

33 CID 6094 Qualitative Concepts for Usage, Exposure Frequency


38 Table CID 6094. Qualitative Concepts for Usage, Exposure Frequency


SNOMED-CTConcept ID


41 Relative dose frequency111584DCM42 Relative frequency of exposure111585DCM43 Relative frequency of use111586DCM

44 - Draft -


1 D Controlled Terminology Definitions (Normative)2 Amend DICOM PS3.16 - Content Mapping Resource - Controlled Terminology Definitions to add the following new concepts:

3 Table D-1. DICOM Controlled Terminology Definitions

4 NotesDefinitionCode MeaningCode Value5 A description of the conditions present during acquisition of images6 of small animals during preclinical research.

Preclinical Small Animal ImagingAcquisition Context

ddd001

7 The conditions present related to the handling of an animal during a8 specified phase.

Animal handling during specifiedphase

ddd005

9 A specified phase of handling of an animal (e.g., transport,10 preparation).

Phase of animal handlingddd006

11 A description of biosafety conditions (e.g., present during small animal12 handling for research).

Biosafety conditionsddd010

13 The reason that biosafety controls are in place.Reason for biosafety controlsddd01114 A description of heating conditions (e.g., present during small animal15 handling for research).

Heating conditionsddd040

16 A description of Circadian effects (e.g., present during small animal17 handling for research).

Circadian effectsddd050

18 A form of face mask that fits over the nose used for delivery of19 inhalational anesthesia (usually for small animals)

Nose coneddd060

20 Cannula inserted in the nose used for delivery of inhalational21 anesthesia or other inhaled gases.

Nasal cannuladdd061

22 A route of administration of a substance via the retro-orbital venous23 sinus.

24 Yardeni T et al. (2011). Retro-orbital injections in mice. Lab Animal,25 40(5), 155–160. doi:10.1038/laban0511-155 http://26 www.ncbi.nlm.nih.gov/pmc/articles/PMC3158461/

Retro-orbital routeddd070

27 The phase of handling of an animal that provides their normal28 environment between procedures.

In home cageddd101

29 The phase of handling of an animal that is transport between30 environments.

During transportddd102

31 The phase of handling of an animal that is staging prior to an imaging32 procedure (e.g., after removal from their home environment and33 transport cage, and awaiting preparation, induction or imaging). During34 this phase the animals are not subject to intervention (e.g., injection,35 catheterization) (cf. ddd104, DCM, "Preparation for imaging")).

Staging prior to imagingddd103

36 The phase of handling of an animal that is preparation prior to an37 imaging procedure that involves handling and intervention (e.g., such38 as injection, catheterization) (cf. ddd103, DCM, "Staging prior to39 imaging")).

Preparation for imagingddd104

40 The phase of handling of an animal during which the housing41 conditions are applicable.

Housing roleddd110

42 The manner in which animals are housed.Animal housingddd12043 The room type in which racks of animal cages are housed.Animal room typeddd12144 The identifier of the room in which racks of animal cages are housed.Animal room identifierddd121b45 The manufacturer of the animal housing.Housing manufacturerddd12546 The manufacturer's product name of the animal housing rack.Housing rack product nameddd126

47 - Draft -




1 NotesDefinitionCode MeaningCode Value2 The manufacturer's product code of the animal housing rack.Housing rack product codeddd1273 The manufacturer's product name of the animal housing unit (or4 bottom of unit if separate lid).

Housing unit product nameddd128

5 The manufacturer's product code of the animal housing unit (or bottom6 of unit if separate lid).

Housing unit product codeddd129

7 The manufacturer's product name of the animal housing unit lid.Housing unit lid product nameddd1308 The manufacturer's product code of the animal housing unit lid.Housing unit lid product codeddd1319 The number of animal housing racks per room.Number of racks per roomddd14010 The number of animal housing units per rack.Number of housing units per rackddd14111 The location of the housing unit in the rack.Housing unit location in rackddd14212 The number of animals in a single housing (e.g., in a single cage, or13 in an animal carrier for imaging).

Number of animals within samehousing unit

ddd143

14 The sex of multiple animals contained in a single housing (cage).Sex of animals within same15 housing unit

ddd144

16 The sex of the animal handler(s).Sex of handlerddd14517 A group consisting of individuals of both sexes (both males and18 females). E.g., a group of animals in a cage, group of animal handlers.

Mixed sexddd146

19 The total period of time that a subject spends in specified housing20 conditions.

Total duration in housingddd150

21 The period of time between changes of housing conditions.Housing change intervalddd15122 The period of time between episodes of manual handling of the23 subject.

Manual handling intervalddd152

24 A description of the manner in which the housing unit is moved (e.g.,25 how a cage is transported).

Housing unit movementddd153

26 The width of the housing unit (e.g., cage).Housing unit widthddd16027 The height of the housing unit (e.g., cage).Housing unit heightddd16128 The length of the housing unit (e.g., cage).Housing unit lengthddd16229 Whether or not the housing unit (e.g., cage) is individually ventilated.Housing individually ventilatedddd17030 How frequently the entire volume of air within a defined space is31 replaced (e.g., within an animal cage).

Air changesddd172

32 Whether or not the housing unit has been previously used for different33 animals.

Housing unit reuseddd175

34 The device (e.g., animal housing unit aka. cage) has not previously35 been used for different animals.

Unusedddd177

36 The device (e.g., animal housing unit aka. cage) has previously been37 used for different animals.

Reusedddd178

38 The manufacturer of the bedding material.Bedding manufacturerddd18039 The manufacturer's product name of the bedding material.Bedding product nameddd18140 The manufacturer's product code of the bedding material.Bedding product codeddd18241 The volume of bedding material.Bedding volumeddd18342 The mass of bedding material.Bedding massddd18443 The depth of bedding material.Bedding depthddd18544 Material provided to enrich the environment of a small animal for the45 purpose of reducing stress, improving health and/or improving46 reproducibility of results. E.g., nesting material.

Enrichment materialddd190

47 - Draft -


1 NotesDefinitionCode MeaningCode Value2 The manufacturer of the material provided to enrich the environment3 of a small animal.

Enrichment manufacturerddd191

4 Whether or not material is provided to enrich the environment of a5 small animal for the purpose of reducing stress, improving health6 and/or improving reproducibility of results. E.g., nesting material.

Enrichment material presentddd192

7 Whether or not an exerciser device is present.Exerciser device presentddd1938 The type of shelter provided for small animals within their housing.Shelter typeddd1959 The manufacturer of the small animal shelter.Shelter manufacturerddd19610 The manufacturer's product name of the small animal shelter.Shelter product nameddd19711 The manufacturer's product code of the small animal shelter.Shelter product codeddd19812 The manufacturer of the feed.Feed manufacturerddd20013 The manufacturer's product name of the feed.Feed product nameddd20114 The manufacturer's product code of the feed.Feed product codeddd20215 The source of animal feed.Feed sourceddd20516 Temperature is regulated by feedback from a temperature sensor17 used to control an active heating or cooling device.

Feedback temperature regulationddd210

18 The total duration of single light-dark cycle (e.g., usually 24 hours).Total duration of light-dark cycleddd21419 The time of day when the lights are turned on.Lights on time of dayddd21520 Igloo shaped small animal shelterIglooddd22021 Red translucent igloo-shaped small animal shelterRed translucent iglooddd22122 Animal bedding material made from aspen chips.Aspen chip beddingddd23023 Animal bedding material made from aspen shavings.Aspen shaving beddingddd23124 Animal bedding material made from (milled) corn cobs.Corn cob beddingddd23225 Animal bedding material made from paper.Paper-based beddingddd23326 Animal bedding material made from pine chips.Pine chip beddingddd23427 Animal bedding material made from pine shavings.Pine shaving beddingddd23528 A device for measuring the temperature of the carrier (holder) used29 for small animal imaging as a means of monitoring or regulating the30 animal's temperature (e.g., a non-magnetic thermocouple embedded31 in or attached to the carrier for MRI).

Carrier temperature sensorddd240

32 A method or device that uses forced hot air to maintain the body33 temperature of a subject.

Forced air heaterddd250

34 An imaging device that contains an integrated method of temperature35 regulation for maintaining the body temperature of the imaging subject.

Heated imaging deviceddd251

36 A device that physically supports the patient and contains an37 integrated method of temperature regulation for maintaining the body38 temperature of the imaging subject (e.g., the carrier used for imaging39 a small animal such as a mouse).

Heated patient supportddd252

40 A blanket that uses circulating hot water to maintain the body41 temperature of a subject.

Heated water blanketddd253

42 A pad that is pre-heated before use that is used to maintain the body43 temperature of a subject (e.g., pre-heated in a microwave or44 autoclave).

Pre-heated padddd254

45 No mechanism is used to maintain the body temperature of a subject.Unheatedddd255

46 - Draft -


1 NotesDefinitionCode MeaningCode Value2 NIH Open Formula Rat and Mouse Ration - 18% Crude Protein3 Autoclavable.

4 Specification at http://www.ors.od.nih.gov/sr/dvr/Documents/SSFiles/5 nih31-137j2004.pdf.

NIH31ddd270

6 NIH07 open-formula, natural-ingredient rodent diet.NIH07ddd2717 AIN76 purified diet.AIN76ddd2728 AIN93 growth diet.AIN93Gddd2739 AIN93 maintenance diet.AIN93Mddd27410 Water that has been purified by reverse osmosis.Reverse osmosis purified waterddd29011 Water that has been purified by reverse osmosis and HCl acidified.Reverse osmosis purified, HCl12 acidified water

ddd291

13 Information about different anesthesia methods used during a14 procedure (from AQI Schema AnesthesiaMethodSetType; see http://15 www.aqihq.org/aqischdoc/AnesthesiaMethodSetType.html).

Anesthesia Method Setddd300

16 Information about a single anesthesia method used during a procedure17 (from AQI Schema AnesthesiaMethodType; see http://www.aqihq.org/18 aqischdoc/AnesthesiaMethodType.html).

Anesthesia Methodddd301

19 Category of anesthesia technique used during a procedure (from AQI20 Schema AnesthesiaCategoryCodeType; see http://www.aqihq.org/21 aqischdoc/AnesthesiaCategoryCodeType.html).

Anesthesia Categoryddd302

22 Details of anesthesia technique used during a procedure (from AQI23 Schema AnesthesiaMethodType; see http://www.aqihq.org/aqischdoc/24 AnesthesiaMethodType.html).

Anesthesia SubCategoryddd303

25 Information about airway management used during a procedure (from26 AQI Schema AirwayManagementSetType; see http://www.aqihq.org/27 aqischdoc/AirwayManagementSetType.html).

Airway Management Setddd310

28 Type of airway management used during a procedure (from AQI29 Schema AirwayManagementMethodCodeType; see http://30 www.aqihq.org/aqischdoc/AirwayManagementMethodCodeType.html).

Airway Management Methodddd312

31 Subtype of airway management of airway management used during32 a procedure (from AQI Schema33 AirwayManagementSubMethodCodeType; see http://www.aqihq.org/34 aqischdoc/AirwayManagementSubMethodCodeType.html).

Airway Sub-Management Methodddd313

35 Set of medications applied during the anesthesia (from AQI Schema36 MedicationsSetType; see http://www.aqihq.org/aqischdoc/37 MedicationsSetType.html).

Medications Setddd320

38 A gas that delivers an inhalational anesthetic to a subject (e.g., air,39 oxygen).

Carrier gasddd330

40 A room for keeping and raising animals for observation or research41 (vivarium).

Animal housing roomddd370

42 A room for preparing a subject (such as a research small animal)43 prior to a procedure (such as an imaging procedure).

Preparation roomddd371

44 A room in which an imaging procedure is performed.Imaging procedure roomddd37245 A product that is locally manufactured (i.e., within the facility or46 institution).

Locally manufactured productddd390

47 A food item that is out of the ordinary and provides pleasure.Food treatddd391

48 - Draft -


http://www.ors.od.nih.gov/sr/dvr/Documents/SSFiles/nih31-137j2004.pdf

http://www.ors.od.nih.gov/sr/dvr/Documents/SSFiles/nih31-137j2004.pdf



http://www.aqihq.org/aqischdoc/AnesthesiaMethodType.html














1 NotesDefinitionCode MeaningCode Value2 A substance from a source external to a subject.

3 E.g., a homograft or xenograft (including tumor cells or tissue), fibrils,4 viruses, cytokines or toxins.

Exogenous substanceddd400

5 The tissue from which a substance originated.

6 E.g., the tissue or organ from which a homograft or xenograft7 (including tumor cells or tissue) was obtained.

Tissue of originddd401

8 The taxonomic rank value (e.g., genus, subgenus, species or9 subspecies) from which a substance originated.

10 E.g., the species of animal from which a homograft or xenograft11 (including tumor cells or tissue) was obtained.

Taxonomic rank of originddd402

12 The three dimensional coordinates that identify a (usually small) target13 within the body.

14 E.g., for the purpose of ablation, biopsy, lesion, injection, stimulation,15 implantation or radiosurgery.

Stereotactic coordinatesddd450

16 The part of the imaging target that was used as a reference point17 associated with a specific Frame of Reference.

18 The Position Reference Indicator may or may not coincide with the19 origin of the fixed frame of reference related to the Frame of20 Reference.

21 For a Patient-related Frame of Reference, this is an anatomical22 reference point, often a well-known surface anatomical point.

Position reference indicatorddd451

23 Tumor cells or tissue or other material obtained from a donor intended24 to be implanted in a research subject.

Tumor graftddd460

25 The kidney of an embryo. E.g., used as the source of human26 embryonic kidney cell lines, though the concept is not specifically27 human.

Embryonic Kidneyddd801

28 - Draft -


1 DICOM PS3.17 Explanatory Information2 Amend DICOM PS3.17 - Explanatory Information to add new Annex XXXX - Preclinical Small Animal Imaging Acquisition Context3 as follows:

4 XXXX Preclinical Small Animal Imaging Acquisition Context (Informative)

5 Amend DICOM PS3.17 - Explanatory Information to add new Annex XXX:

6 XXXX.1 7 This Annex describes the use of Preclinical Small Animal Imaging Acquisition Context.

8 XXXX.1.1 Example of housing and anesthesia for PET-CT

9 This Section contains examples for use cases involving imaging of a single animal in a hybrid PET-CT system.

10 The basic use case involves an animal, which:

11 • lives in an individually ventilated home cage with several other animals in the same cage

12 • is (briefly) transported (in its home cage) with its cage mates to the imaging facility, without heating, with an appropriate lid

13 • is removed from its home/transport cage for preparation for imaging, involving insertion of a tail vein cannula, performed on an14 electrically heated pad

15 • is induced by (a) placement in an induction chamber with more concentrated volatile anesthetic, or (b) intraperitoneal injection of16 Ketamine mixture

17 • is placed in a PET-CT compatible imaging sled/carrier/chamber for imaging (of one animal at a time), with anesthesia with Isoflurane18 and Oxygen as the carrier gas, and heated with an electric pad regulated by feedback from a rectal probe

19 • is removed for recovery in a separate cage

20 The content tree structure (when induction is by a volatile anesthetic) would resemble:

21 TIDCode Meaning or Example22 Value

Code Meaning of Concept NameNode

23 TID ttt01Preclinical Small Animal Imaging24 Acquisition Context

1

25 TID 1204EnglishLanguage of Content Item and26 Descendants

1.1

27 TID 1204United StatesCountry of Language1.1.228 TID 1003Doe^JanePerson Observer Name1.229 TID 1005

30 CID 100

PET/CT FDG imaging of whole31 body

Procedure Code1.3

32 TID ttt10Biosafety conditions1.433 TID ttt10

34 CID bsl01

Biosafety level 1Biosafety level1.4.1

35 TID ttt01Animal handling during specified phase1.536 TID ttt01

37 CID pha01

In home cagePhase of animal handling1.5.1

38 - Draft -




3 TID ttt21Animal housing1.5.24 TID ttt21Innovive, San Diego, CAHousing manufacturer1.5.2.15 TID ttt21Innorack IVC Mouse 3.5Housing rack product name1.5.2.26 TID ttt21Innocage Mouse Pre-Bedded7 Corn Cob with Enrichment

Housing unit product name1.5.2.3

8 TID ttt21M-BTM-C8EHousing unit product code1.5.2.49 TID ttt21Innocage IVC Mouse Single10 Filter

Housing unit lid product name1.5.2.5

11 TID ttt21MV1Housing unit lid product code1.5.2.612 TID ttt214 {racks}Number of racks per room1.5.2.713 TID ttt21154 {housing units}Number of housing units per rack1.5.2.814 TID ttt21Row 4 Column 7Housing unit location in rack1.5.2.915 TID ttt215 {animals}Number of animals per housing1.5.2.1016 TID ttt21FemaleSex of animals within housing1.5.2.1117 TID ttt21MixedSex of handler1.5.2.1218 TID ttt21133 daysTotal duration in housing1.5.2.1319 TID ttt217 daysHousing change interval1.5.2.1420 TID ttt2124 hoursManual handling interval1.5.2.1521 TID ttt2123.4 cmHousing unit width1.5.2.1622 TID ttt2114.0 cmHousing unit height1.5.2.1723 TID ttt2137.3 cmHousing unit length1.5.2.1824 TID ttt21

25 CID yesnoonly

YesHousing individually ventilated1.5.2.19

26 TID ttt2150 /hourAir changes1.5.2.2027 TID ttt2122 CEnvironmental temperature1.5.2.2128 TID ttt2150 %Housing humidity1.5.2.2229 TID ttt21

30 CID dsp01

UnusedHousing unit reuse1.5.2.23

31 TID ttt21

32 CID bed01

Corn cob beddingBedding material1.5.2.24

33 TID ttt21450 mlBedding volume1.5.2.2534 TID ttt21Innorichment paper twistsEnrichment material1.5.2.2635 TID ttt21InnowheelExerciser device1.5.2.2736 TID ttt21

37 CID she01

Red translucent iglooShelter1.5.2.28

38 TID ttt21

39 CID she01

Innovive, San Diego, CAShelter manufacturer1.5.2.29

40 TID ttt21

41 CID she01

InnoDomeShelter product name1.5.2.30

42 - Draft -





5 CID pha01

During transportPhase of animal handling1.6.1

6 TID ttt21Animal housing1.6.27 TID ttt21Innovive, San Diego, CAHousing manufacturer1.6.2.18 TID ttt21Innocage Mouse Pre-Bedded9 Corn Cob with Enrichment


10 TID ttt21M-BTM-C8EHousing unit product code1.6.2.311 TID ttt21Innocage Mouse TransportHousing unit lid product name1.6.2.412 TID ttt21MS4Housing unit lid product code1.6.2.513 TID ttt215 {animals}Number of animals per housing1.6.2.614 TID ttt21FemaleSex of animals within housing1.6.2.715 TID ttt40Heating conditions1.6.316 TID ttt40

17 CID hea01

UnheatedHeating1.6.3.1


20 CID pha01

Staging prior to imagingPhase of animal handling1.7.1


23 CID pha01

Preparation for imagingPhase of animal handling1.8.1

24 TID ttt21Animal housing1.8.225 TID ttt21Animal exposed and restrained26 whilst cannulating tail vein

Comment1.8.2.1

27 TID ttt40Heating conditions1.8.328 TID ttt40

29 CID hea01

Electric heating padHeating1.8.3.1

30 TID ttt40

31 CID yesnoonly

NoFeedback temperature regulation1.8.3.2


34 CID pha01

Anesthesia inductionPhase of animal handling1.9.1

35 TID ttt21Animal housing1.9.236 TID ttt21Leica BiosystemsHousing manufacturer1.9.2.137 TID ttt21Gas Anesthesia Induction38 Chamber f/Mouse


39 TID ttt2139481051Housing unit product code1.9.2.340 TID ttt01Animal handling during specified phase1.10

41 - Draft -




3 TID ttt01

4 CID pha01

Imaging procedurePhase of animal handling1.10.1

5 TID ttt01yyyymmddhhssDateTime Started1.10.26 TID ttt01yyyymmddhhssDateTime Ended1.10.37 TID ttt21Animal housing1.10.48 TID ttt21m2m imagingHousing manufacturer1.10.4.19 TID ttt21BioVet Multimodal Mouse10 Chamber


11 TID ttt40Heating conditions1.10.512 TID ttt40

13 CID hea01

Electric heating padHeating1.10.5.1

14 TID ttt40

15 CID yesnoonly

YesFeedback temperature regulation1.10.5.1

16 TID ttt40

17 CID hea02

Rectal temperatureTemperature sensor device component1.10.5.2

18 TID ttt4037 CEquipment Temperature1.10.5.319 TID ttt70Physiological Monitoring1.10.620 TID ttt70

21 CID yesnoonly

YesElectrocardiographic monitoring1.10.6.1

22 TID ttt70

23 CID yesnoonly

NoMonitoring of respiration1.10.6.2


26 CID pha01

Anesthesia recovery periodPhase of animal handling1.11.1

27 TID ttt30Administration of anesthesia1.1228 TID ttt30Anesthesia Method Set1.12.129 TID ttt30Anesthesia Method1.12.1.130 TID ttt30

31 CID ans01

General anesthesiaAnesthesia Category1.12.1.1.1

32 TID ttt30yyyymmddhhssAnesthesia Start Time1.12.1.1.233 TID ttt30yyyymmddhhssAnesthesia Finish Time1.12.1.1.334 TID ttt30

35 CID ans02

By inhalationAnesthesia Induction1.12.1.1.4

36 TID ttt30

37 CID ans03

Inhalation anesthesia, machine38 system, closed, no rebreathing39 of primary agent

Anesthesia Maintenance1.12.1.1.5

40 TID ttt30Airway Management Set1.12.241 TID ttt30Airway Management1.12.2.1

42 - Draft -




3 TID ttt30

4 CID ans04

Nose coneAirway Management Method1.12.2.1.1

5 TID ttt30Medications Set1.12.36 TID ttt30

7 CID ans12

During procedureProcedure Phase1.12.3.1

8 TID ttt31Medication given1.12.3.29 TID ttt31yyyymmddhhssDrug start1.12.3.2.110 TID ttt31yyyymmddhhssDrug end1.12.3.2.211 TID ttt31

12 CID 11

By inhalationRoute of administration1.12.3.2.3

13 TID ttt31Mixture1.12.3.2.414 TID ttt31

15 CID ans07

IsofluraneDrug administered1.12.3.2.4.1

16 TID ttt31

17 CID ans06

General anestheticMedication Type1.12.3.2.4.2

18 TID ttt314 %Concentration1.12.3.2.4.319 TID ttt31Mixture1.12.3.2.520 TID ttt31

21 CID ans07

OxygenDrug administered1.12.3.2.5.1

22 TID ttt31

23 CID ans06

Carrier gasMedication Type1.12.3.2.5.2

24 TID ttt31100 %Concentration1.12.3.2.5.325 TID ttt31Medication given1.12.3.326 TID ttt31yyyymmddhhssDrug start1.12.3.3.127 TID ttt31yyyymmddhhssDrug end1.12.3.3.228 TID ttt31

29 CID 11

By inhalationRoute of administration1.12.3.3.3


32 CID ans07

IsofluraneDrug administered1.12.3.3.4.1

33 TID ttt31

34 CID ans06


35 TID ttt312 %Concentration1.12.3.3.4.336 TID ttt31Mixture1.12.3.3.537 TID ttt31

38 CID ans07

OxygenDrug administered1.12.3.3.5.1

39 - Draft -




3 TID ttt31

4 CID ans06

Carrier gasMedication Type1.12.3.3.5.2

5 TID ttt31100 %Concentration1.12.3.3.5.3

6 The content tree structure when induction is by intra-peritioneal injection might be different in the following way, in that the housing7 during the induction phase does not involve a chamber, and the injected agent is specified, as follows:



10 ............11 TID ttt01Animal handling during specified12 phase

1.9

13 TID ttt01

14 CID pha01

Anesthesia inductionPhase of animal handling1.9.1

15 TID ttt21Animal housing1.9.216 TID ttt21Animal exposed whilst inducing17 anesthesia

Comment1.9.2.1

18 ............19 TID ttt30Administration of anesthesia1.1220 TID ttt30Anesthesia Method Set1.12.121 TID ttt30Anesthesia Method1.12.1.122 TID ttt30

23 CID ans01

General anesthesiaAnesthesia Category1.12.1.1.1

24 TID ttt30yyyymmddhhssAnesthesia Start Time1.12.1.1.225 TID ttt30yyyymmddhhssAnesthesia Finish Time1.12.1.1.326 TID ttt30

27 CID ans02

Intraperitoneal routeAnesthesia Induction1.12.1.1.4

28 TID ttt30

29 CID ans03

Inhalation anesthesia, machine30 system, closed, no rebreathing31 of primary agent

Anesthesia Maintenance1.12.1.1.5

32 ............33 TID ttt30Medications Set1.12.334 TID ttt30

35 CID ans12

During procedureProcedure Phase1.12.3.1

36 TID ttt31Medication given1.12.3.237 TID ttt31yyyymmddhhssDrug start1.12.3.2.138 TID ttt31

39 CID 11

Intraperitoneal routeRoute of administration1.12.3.2.2


42 CID ans07

KetamineDrug administered1.12.3.2.3.1

43 - Draft -




3 TID ttt31

4 CID ans06


5 TID ttt31nn mgDosage1.12.3.2.3.26 TID ttt31Mixture1.12.3.2.47 TID ttt31

8 CID ans07

MedetomidineDrug administered1.12.3.2.4.1

9 TID ttt31

10 CID ans06


11 TID ttt31nn mgDosage1.12.3.2.4.212 ............

13 XXXX.1.2 Example of exogenous substance administration to encode tumor cell line

14 Only the exogenous substance information is included in this example and content describing animal handling, anesthesia information,15 etc. is excluded for clarity. Indeed, given the optionality of the other content, it would be possible to create an Acquisition Context SR16 instance that describes only the exogenous substance information and nothing else.

17 The content tree structure would resemble:



20 TID ttt01Preclinical Small Animal Imaging21 Acquisition Context

1

22 TID 1204EnglishLanguage of Content Item and23 Descendants

1.1

24 TID 1204United StatesCountry of Language1.1.225 TID 1003Doe^JanePerson Observer Name1.226 ............27 TID ttt82Exogenous substance1.n28 TID ttt82

29 CID exo01

30 CID exo10

AdenocarcinomaTumor Cell Graft1.n.1

31 TID ttt82

32 CID 7456 "Units of Measure for Age"

6 weekAge Started1.n.2

33 TID ttt82yyyymmddhhssDateTime Started1.n.334 TID ttt82MDA-MB-468Brand name1.n.435 TID ttt82

36 CID 6092

10E6 {cells}Dosage1.n.5

37 TID ttt82

38 CID 6094

39 CID 6091

Single eventRelative dose frequency1.n.6

40 - Draft -




3 TID ttt82

4 CID 11

Subcutaneous routeRoute of Administration1.n.7

5 TID ttt82

6 CID exo30

FlankSite of1.n.7.1

7 TID ttt82

8 CID 244

LeftLaterality1.n.7.1.1

9 TID ttt82

10 CID exo50

BreastTissue of origin1.n.8

11 TID ttt82

12 CID 7454 "Animal Taxonomic Rank13 Values"

homo sapiensTaxonomic rank of origin1.n.9

14 XXXX.1.3 Informative References

15 XXXX.1.3.1 Method Descriptions

16 [Stout et al 2013] Molecular Imaging. Stout D, Berr SS, LeBlanc A, Kalen JD, Osborne D, Price J, Schiffer W, Kuntner C, and Wall J.17 2013. 12. 7. 1-15. “Guidance for Methods Descriptions Used in Preclinical Imaging Papers”. http://mi.deckerpublishing.com/18 index.php/article/guidance-for-methods-descriptions-used-in-preclinical-imaging-papers .

19 [David et al 2013a] Comparative Medicine. David JM, Chatziioannou AF, Taschereau R, Wang H, and Stout DB. 2013. 63. 5. 386–91.20 “The Hidden Cost of Housing Practices: Using Noninvasive Imaging to Quantify the Metabolic Demands of Chronic Cold21 Stress of Laboratory Mice”. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796748/ .

22 [David et al 2013b] Journal of the American Association for Laboratory Animal Science. David JM, Knowles S, Lamkin DM, and Stout23 DB. 2013. 52. 6. 738–44. “Individually Ventilated Cages Impose Cold Stress on Laboratory Mice: A Source of Systemic Ex-24 perimental Variability”. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838608/ .

25 [Rosenbaum et al 2009] Journal of the American Association for Laboratory Animal Science. Rosenbaum MD. 2009. 48. 6. 763–73.26 “Effects of Cage-Change Frequency and Bedding Volume on Mice and Their Microenvironment”. http://www.ncbi.nlm.nih.gov/27 pmc/articles/PMC2786931/ .

28 [Fueger et al 2006] Journal of Nuclear Medicine. Fueger BJ. 2006. 47. 6. 999–1006. “Impact of Animal Handling on the Results of29 18F-FDG PET Studies in Mice”. http://jnm.snmjournals.org/content/47/6/999 .

30 [Dandekar et al 2007] Journal of Nuclear Medicine. Dandekar M. 2007. 48. 4. 602–7. “Reproducibility of 18F-FDG microPET Studies31 in Mouse Tumor Xenografts”. 10.2967/jnumed.106.036608. http://jnm.snmjournals.org/content/48/4/602 .

32 [Lee et al 2005] Journal of Nuclear Medicine. Lee KH. 2005. 46. 9. 1531–36. “Effects of Anesthetic Agents and Fasting Duration on33 18F-FDG Biodistribution and Insulin Levels in Tumor-Bearing Mice”. http://jnm.snmjournals.org/content/46/9/1531 .

34 [Balcombe et al 2004] Journal of the American Association for Laboratory Animal Science. Balcombe JP. 2004. 43. 6. 42–51.35 “Laboratory Routines Cause Animal Stress”. .

36 [Van der Meer et al 2004] Journal of the American Association for Laboratory Animal Science. Van der Meer E. 2004. 38. 4. 376–83.37 “Short-term effects of a disturbed light–dark cycle and environmental enrichment on aggression and stress-related parameters38 in male mice”. http://www.animalexperiments.info/resources/Studies/Animal-impacts/Stress.-Balcombe-et-al-2004./39 Stress-Balcombe-et-al-2004.pdf .

40 [Tabata et al 1998] Laboratory Animals. Tabata H. 1998. 32. 2. 143–48. “Comparison of Effects of Restraint, Cage Transportation,41 Anaesthesia and Repeated Bleeding on Plasma Glucose Levels between Mice and Rats”. 10.1258/002367798780599983.42 http://lan.sagepub.com/content/32/2/143 .

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http://mi.deckerpublishing.com/index.php/article/guidance-for-methods-descriptions-used-in-preclinical-imaging-papers

http://mi.deckerpublishing.com/index.php/article/guidance-for-methods-descriptions-used-in-preclinical-imaging-papers





http://jnm.snmjournals.org/content/47/6/999



http://www.animalexperiments.info/resources/Studies/Animal-impacts/Stress.-Balcombe-et-al-2004./Stress-Balcombe-et-al-2004.pdf

http://www.animalexperiments.info/resources/Studies/Animal-impacts/Stress.-Balcombe-et-al-2004./Stress-Balcombe-et-al-2004.pdf

http://lan.sagepub.com/content/32/2/143

1 DICOM PS3.3 Information Object Definitions2 3 Definitions3 Amend DICOM PS3.3 - Information Object Definitions - Section 3 - Definitions, to add definition of Acquisition Context.

4 For the purposes of this Standard the following definitions apply.

5 3.8 DICOM Information Object

6 Acquisition Context A description of the conditions present during data acquisition.

7 A Composite Information Object Definitions (Normative)8 Amend DICOM PS3.3 - Information Object Definitions - Annex A - Composite Information Object Definitions (Normative), to add9 Acquisition Context IOD Modules to A.1.4 Overview of the Composite IOD Module Content.

10 Amend DICOM PS3.3 - Information Object Definitions - Annex A - Composite Information Object Definitions (Normative) as follows,11 to add a new Acquisition Context Structured Report IOD:

12 A.35.x Acquisition Context SR IOD

13 A.35.x.1 Acquisition Context SR Information Object Description14 The Acquisition Context SR IOD is used to represent the description of the conditions present during data acquisition of other data15 that is stored separately (such as images).

16 A.35.x.2 Acquisition Context SR IOD Entity-Relationship Model17 The E-R Model in Section A.1.2 applies to the Acquisition Context SR IOD.

18 A.35.x.3 Acquisition Context SR IOD Module Table19 Table A.35.x-1 specifies the Modules of the Acquisition Context SR IOD.

20 Table A.35.x-1. Acquisition Context SR IOD Modules

21 UsageReferenceModuleIE22 MC.7.1.1PatientPatient23 UC.7.1.3Clinical Trial Subject24 MC.7.2.1General StudyStudy25 UC.7.2.2Patient Study26 UC.7.2.3Clinical Trial Study27 MC.17.1SR Document SeriesSeries28 UC.7.3.2Clinical Trial Series29 C - Required if time30 synchronization was applied

C.7.4.2SynchronizationFrame ofReference

31 MC.7.5.1General EquipmentEquipment32 MC.7.5.2Enhanced General Equipment33 MC.17.2SR Document GeneralDocument34 MC.17.3SR Document Content

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1 UsageReferenceModuleIE2 MC.12.1SOP Common

3 A.35.x.3.1 Acquisition Context SR IOD Content Constraints

4 A.35.x.3.1.1 Value Type

5 Value Type (0040,A040) in Content Sequence (0040,A730) of the SR Document Content Module is constrained to the following6 Enumerated Values (see Table C.17.3-7 for Value Type definitions):

7 Enumerated Values:

8 TEXT9 CODE10 NUM11 DATETIME12 DATE13 TIME14 UIDREF15 PNAME16 SCOORD3D17 CONTAINER

18 A.35.x.3.1.2 Relationship Constraints

19 Relationships between Content Items in the content of this IOD shall be conveyed in the by-value mode. See Table C.17.3-8 for Re-20 lationship Type definitions.

21 Note

22 Relationships by-reference are forbidden. Therefore, Referenced Content Item Identifier (0040,DB73) is not present in any23 of the Content Items within the SR Document Content Module.

24 Table A.35.x-2 specifies the relationship constraints of this IOD.

25 Table A.35.x-2. Relationship Content Constraints for Acquisition Context SR IOD

26 Target Value TypeRelationship Type (Enumerated Values)Source Value Type27 CODE, CONTAINER, DATETIME, NUM, PNAME,28 TEXT, UIDREF

CONTAINSCONTAINER

29 CODE, DATE, DATETIME, PNAME, TEXT, TIME,30 UIDREF

HAS OBS CONTEXTCONTAINER

31 CODEHAS OBS CONTEXTCODE32 CODE, TEXT33 1HAS CONCEPT MODany type34 CODE, DATETIME, NUM, SCOORD3D, TEXTHAS PROPERTIESCODE

35 Note

36 The HAS CONCEPT MOD relationship is used to modify the meaning of the Concept Name of a Source Content Item, for37 example to provide a more descriptive explanation, a different language translation, or to define a post-coordinated concept.

38 A.35.x.3.1.3 Template Constraints

39 The document may be constructed from Baseline TID ttt01 “Preclinical Small Animal Image Acquisition Context” invoked at the root40 node.

41 Note

42 This IOD maybe used with other Templates defined for Acquisition Context.

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1 DICOM PS3.4 Service Class Specifications2 B Storage Service Class (Normative)3 Amend DICOM PS3.4 - Service Class Specifications - Annex B - Storage Service Class (Normative) as follows:

4 B.3.1.4 Related General SOP Classes (A-ASSOCIATE-RQ)

5 ...

6 Table B.3-3. Standard and Related General SOP Classes

7 Related General SOP Class NameSOP Class Name8 ......9 Enhanced SRRadiopharmaceutical Radiation Dose10 SR11 Comprehensive SR12 Comprehensive 3D SR13 Extensible SR14 Enhanced SR (see note)Acquisition Context SR15 Comprehensive SR (see note)16 Comprehensive 3D SR17 Extensible SR18 ......

19 Note

20 The Acquisition Context SR may be encoded as Enhanced or Comprehensive only if it does not contain stereotactic21 coordinates (SCOORD3D).

22 B.5 Standard SOP Classes

23 ...

24 Table B.5-1. Standard SOP Classes

25 IOD Specification (defined in PS3.3)SOP Class UIDSOP Class Name26 .........27 Acquisition Context SR IOD1.2.840.10008.5.1.4.1.1.nnnnn1Acquisition Context SR Storage28 .........

29 B.5.1.5 Structured Reporting Storage SOP Classes

30 The requirements of Annex O apply to the following SOP Classes:

31 • ...

32 • Acquisition Context SR

33 I Media Storage Service Class (Normative)34 Amend DICOM PS3.4 - Service Class Specifications - Annex I - Media Storage Service Class (Normative) as follows:

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1 I.4 Media Storage Standard SOP Classes

2 ...

3 Table I.4-1. Media Storage Standard SOP Classes

4 IOD Specification (defined in PS3.3)SOP Class UIDSOP Class Name5 .........6 Acquisition Context SR IOD1.2.840.10008.5.1.4.1.1.nnnnn1Acquisition Context SR Storage7 .........

8 I.4.1.2 Structured Reporting Storage SOP Classes

9 The requirements of Annex O apply to the following SOP Classes:

10 • ...

11 • Acquisition Context SR

12 - Draft -


1 DICOM PS3.6 Data Dictionary2 A Registry of DICOM Unique Identifiers (UIDs) (Normative)3 Amend DICOM PS3.6 - Data Dictionary - Annex A - Registry of DICOM Unique Identifiers (UIDs) as follows:

4 Table A-1. UID Values

5 PartUID TYPEUID NAMEUID Value6 ............7 PS3.4SOP ClassAcquisition Context SR Storage1.2.840.10008.5.1.4.1.1.nnnnn18 ............

9 Table A-3. Context Group UID Values

10 Context Group NameContext IdentifierContext UID11 .........

12 - Draft -


1 DICOM PS3.2 Conformance2 A DICOM Conformance Statement Template (Normative)3 Amend DICOM PS3.2 - Conformance - Annex A - DICOM Conformance Statement Template (Normative) as follows:

4 Table A.1-2. UID Values

5 CategoryUID NameUID Value6 .........7 TransferAcquisition Context SR Storage SOP Class1.2.840.10008.5.1.4.1.1.nnnnn18 .........

9 - Draft -


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