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A.acetic  -Keto glutaric Pyrole Proto-

porphyrin

Protoporphyrin III + Fe2+ Heme

4 Heme + Globin Hemoglobin

Krebs

Glycin

Sự thành lập Hemoglobin

4.66% 0.34%

5% 94%

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Globin chain synthesis

Wee ! "onth 3 # $b Goer

&  'ξ'()

$b Po*lan+ &  'ε'(

"onth 3 "onth 6 # $b, &  'γ'(

"onth 6 nant # $b,↓

 ) $bA↑

A+ult # $bA &  ' '( /95% $bA' 

& 

'δ

'( 3%

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 Ý nghĩa xét nghiệm

Một trong 3 xét nghiệm căn bản nhằm đánh giátình trng thi!" má" # Hct$ %&'$ Hb (

 

MCV !"l#

  MCH !pg#

  MCHC !g$%#

H&t

'(C

Hb'(C

H&tHb

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PH)*G PH,P -. H/M.G%.(I

0ahli1Hellige Cyanmethemoglobin

PP 0o m3 PP -o 3ang

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 -5nh l67ng hemoglobin

b8ng ph69ng ph:p ;o m3

!0ahli1Hellige#

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<1 g3y=n t>&

Hb !m:3 ton ph?n#

HCl @A< <@B

&iD Hematine

/E Pha long

0o m3 aAHematine $ ;>& J

 -K& Jt 3L tr& tiJp tr=n Nng nghiệm !g$Dl#

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21 EOng &O

(

;o m30ahli

Hellige

 -Qa thRy tinh ;>& J

Sng nghiệm 0ahli !gT#

Pipette 0ahli

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U1 Ho: &ht

ChlohyDri&a&iD @A<

6W&Ct

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41 (ệnh phXm

MaY mao 3Ln Z ho[& m:3 tĩnh m\&h

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h] HCl @A< ^o Nngnghiệm 0ahli _Jn ^\&h

2gT

`im tra t=n ( l>& _c3 Nng m:3

 (6W&& <d Ch3Xn b5

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 (6W& 2d iJn hnh phLn ng

Eng pipette 0ahli hYt2@f% m:3%a3 ;\&h m:3 Dnhngoi pipetteA

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Phn phNi m:3 ^oNng nghiệm & ;jn

HCl @A<

Eng _Qa thRy tinhtrn _c3 m:3 HCl

@A<

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%63 kdHYt D3ng D5&h trong Nng nghiệm tr:ng

;\&h m:3 trong pipette 21U l?n

rong 3: trnh phn phNi m:3 trn

_c3 tr:nh hng &ho ni bKt trong Nng

nghiệmA

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S)" *+,$ -./ Hb bi!nthành )0Hem)tine mà"

n1" 2m

 45 67n trong *+ph8t

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<A9h) lo:ng bằng

n;<c c=t

2A>rộn đ?"

UASo mà" @<i thA6

tinh m"

>i!p tBc ph)

lo:ng n!"

mà" phản

Cng ch;)

trDng @<i mà"

thA6 tinh m"

<A

2A

UA

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 (6W& Ud -K& Jt 3L

 -K& Jt 3L tr& tiJp

tr=n thn Nng nghiệm

!&on ;N n8m ngang ^Wim[t _:y &ong &Ra D3ng

D5&h trong Nng nghiệm#

 -9n ^5 tnhd gT g$<@@ml(

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q1 (iện l3n

r5 ;N bnh th3sngd

E r emd

E + 09 ;inh _R th:ngd <UAu v 2 g$Dl

E + r U th:ng t3i d wAu v 2 g$DlE + r em < t3i d <2A@ v 2 g$Dl

E g6si lWnd

E + am d <4 1 < g$Dl !<q v 2#

E + d <2 1 <q g$Dl !<4 v 2#

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q1 (iezn l3azn

Hemoglobin giLmd thiJ3 m:3

Hemoglonin t{ngd

E + -a h|ng &?3A

E + Hb t{ng giLd hi th& hiện b8ng pp 0ahli ^Wi m}3

m:3 & ~(C •<@@A@@@$mmU  `€ Hb t{ng u1<@T ;o

^Wi gi: tr5 th&A

%63 kd HbF &3L bo thai Met1Hb ^ mt ;N D}n x3t

&Ra Hb hng biJn thnh a&iD HematineA

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1 g3y=n nhn ;ai l?m

Eo DOng &Od thRy tinh m}3 hng &h3XnA

Eo ha &htd HCl 3: thsi h\n hng _Yng n|ng _A

Eo ‚ th3td

Sng nghiệm & bKtA

 -K& Jt 3L ^i ^A

0o m3 hng _R _ic3 iện :nh ;:ngA